{
	"name":"sky01011",
	"children":[
	{
		"name":"Precursor biosynthesis",
		"children":[
		{
			"name":"Transferase\/Dehydrogenase",
			"children":[
			{
				"name":"D0C37_05370 UDP-N-acetylglucosamine 1-carboxyvinyltransferase\tK00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]"
			},
			{
				"name":"D0C37_10950 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase\tK00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]"
			},
			{
				"name":"D0C37_20120 UDP-N-acetylmuramate dehydrogenase\tK00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]"
			}
			]
		},
		{
			"name":"Amino acid ligase",
			"children":[
			{
				"name":"D0C37_05085 UDP-N-acetylmuramate--L-alanine ligase\tK01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]"
			},
			{
				"name":"D0C37_25850 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase\tK01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]"
			},
			{
				"name":"D0C37_25835 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase\tK01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]"
			},
			{
				"name":"D0C37_07810 D-alanine--D-alanine ligase\tK01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]"
			}
			]
		},
		{
			"name":"Racemase",
			"children":[
			{
				"name":"D0C37_20580 alr; alanine racemase\tK01775 alr; alanine racemase [EC:5.1.1.1]"
			},
			{
				"name":"D0C37_01475 glutamate racemase\tK01776 murI; glutamate racemase [EC:5.1.1.3]"
			}
			]
		},
		{
			"name":"Carboxypeptidase",
			"children":[
			{
				"name":"D0C37_03730 LD-carboxypeptidase\tK01297 ldcA; muramoyltetrapeptide carboxypeptidase [EC:3.4.17.13]"
			}
			]
		},
		{
			"name":"Glycosyltransferase",
			"children":[
			{
				"name":"D0C37_25845 phospho-N-acetylmuramoyl-pentapeptide-transferase\tK01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]"
			},
			{
				"name":"D0C37_25860 murG; undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase\tK02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]"
			}
			]
		},
		{
			"name":"Diphosphatase",
			"children":[
			{
				"name":"D0C37_29595 undecaprenyl-diphosphate phosphatase\tK06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]"
			},
			{
				"name":"D0C37_15225 phosphatase PAP2 family protein\tK19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27]"
			}
			]
		},
		{
			"name":"Flippase",
			"children":[
			{
				"name":"D0C37_07995 murJ; murein biosynthesis integral membrane protein MurJ\tK03980 murJ; putative peptidoglycan lipid II flippase"
			},
			{
				"name":"D0C37_16510 murJ; murein biosynthesis integral membrane protein MurJ\tK03980 murJ; putative peptidoglycan lipid II flippase"
			}
			]
		}
		]
	},
	{
		"name":"Peptidoglycan biosynthesis and degradation",
		"children":[
		{
			"name":"Glycosyltransferase\/DD-Transpeptidase (Class A PBP)",
			"children":[
			{
				"name":"D0C37_22270 penicillin-binding protein\tK05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]"
			}
			]
		},
		{
			"name":"DD-Transpeptidase (Class B PBP)",
			"children":[
			{
				"name":"D0C37_23415 mrdA; penicillin-binding protein 2\tK05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]"
			},
			{
				"name":"D0C37_25830 penicillin-binding protein 2\tK03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]"
			},
			{
				"name":"D0C37_09205 penicillin-binding protein 2\tK05364 pbpA; penicillin-binding protein A"
			},
			{
				"name":"D0C37_16285 penicillin-binding protein 2\tK05364 pbpA; penicillin-binding protein A"
			}
			]
		},
		{
			"name":"DD-Carboxypeptidase\/DD-Endopeptidase (Low molecular weight PBP)",
			"children":[
			{
				"name":"D0C37_12765 D-alanyl-D-alanine carboxypeptidase\tK07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5\/6) [EC:3.4.16.4]"
			},
			{
				"name":"D0C37_16125 D-alanyl-D-alanine carboxypeptidase\tK07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5\/6) [EC:3.4.16.4]"
			},
			{
				"name":"D0C37_21275 DUF5136 domain-containing protein\tK07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5\/6) [EC:3.4.16.4]"
			},
			{
				"name":"D0C37_31800 D-alanyl-D-alanine carboxypeptidase\tK07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5\/6) [EC:3.4.16.4]"
			},
			{
				"name":"D0C37_18820 dacB; D-alanyl-D-alanine carboxypeptidase\/D-alanyl-D-alanine-endopeptidase\tK07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase\/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-]"
			}
			]
		},
		{
			"name":"Glycosyltransferase",
			"children":[
			{
				"name":"D0C37_09200 FtsW\/RodA\/SpoVE family cell cycle protein\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
			},
			{
				"name":"D0C37_16280 FtsW\/RodA\/SpoVE family cell cycle protein\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
			},
			{
				"name":"D0C37_25855 ftsW; putative lipid II flippase FtsW\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
			},
			{
				"name":"D0C37_23420 rodA; rod shape-determining protein RodA\tK05837 rodA; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
			}
			]
		},
		{
			"name":"Transpeptidase"
		},
		{
			"name":"Carboxypeptidase",
			"children":[
			{
				"name":"D0C37_29265 D-alanyl-D-alanine dipeptidase\tK08641 vanX; zinc D-Ala-D-Ala dipeptidase [EC:3.4.13.22]"
			},
			{
				"name":"D0C37_00945 peptidase M15\tK08640 E3.4.17.14; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14]"
			},
			{
				"name":"D0C37_08280 peptidase M15\tK08640 E3.4.17.14; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14]"
			}
			]
		},
		{
			"name":"Endopeptidase",
			"children":[
			{
				"name":"D0C37_09225 hypothetical protein\tK21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-]"
			},
			{
				"name":"D0C37_14445 glycoside hydrolase\tK21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-]"
			},
			{
				"name":"D0C37_19800 NlpC\/P60 family protein\tK21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-]"
			},
			{
				"name":"D0C37_20910 NlpC\/P60 family protein\tK21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-]"
			},
			{
				"name":"D0C37_20935 glycoside hydrolase\tK21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-]"
			},
			{
				"name":"D0C37_25570 hypothetical protein\tK21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-]"
			},
			{
				"name":"D0C37_25575 NlpC\/P60 family protein\tK21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-]"
			}
			]
		},
		{
			"name":"Sortase",
			"children":[
			{
				"name":"D0C37_16305 class E sortase\tK07284 srtA; sortase A [EC:3.4.22.70]"
			}
			]
		},
		{
			"name":"Lytic transglycosylase",
			"children":[
			{
				"name":"D0C37_28810 mltG; endolytic transglycosylase MltG\tK07082 mltG; peptidoglycan lytic transglycosylase G [EC:4.2.2.29]"
			}
			]
		},
		{
			"name":"Amidase",
			"children":[
			{
				"name":"D0C37_24645 N-acetylmuramoyl-L-alanine amidase\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
			}
			]
		},
		{
			"name":"Structural protein"
		}
		]
	}
	]
}