{
	"name":"spo04131",
	"children":[
	{
		"name":"Exocytosis",
		"children":[
		{
			"name":"Calcium ion-dependent exocytosis",
			"children":[
			{
				"name":"Synaptotagmins"
			},
			{
				"name":"Septins",
				"children":[
				{
					"name":"2543516 spn1; mitotic septin Spn1\tK16944 SEPT7; septin 7"
				}
				]
			},
			{
				"name":"DOC-2 proteins"
			},
			{
				"name":"Acrosomal exocytosis proteins",
				"children":[
				{
					"name":"2539517 ksg1; serine\/threonine protein kinase Ksg1\tK06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]"
				}
				]
			},
			{
				"name":"Phospholipases",
				"children":[
				{
					"name":"2541439 plc1; phosphoinositide phospholipase C Plc1\tK05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]"
				},
				{
					"name":"2542065 pld1; phospholipase D Pld1\tK01115 PLD1_2; phospholipase D1\/2 [EC:3.1.4.4]"
				}
				]
			},
			{
				"name":"Kinases and associated proteins",
				"children":[
				{
					"name":"2542231 its3; 1-phosphatidylinositol-4-phosphate 5-kinase Its3\tK00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]"
				},
				{
					"name":"2539997 shk1; PAK-like kinase Shk1\tK04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]"
				},
				{
					"name":"2541473 ppk11; PAK-like kinase Ppk11\tK08838 STK24_25_MST4; serine\/threonine-protein kinase 24\/25\/MST4 [EC:2.7.11.1]"
				},
				{
					"name":"2542746 sid1; PAK-like GC kinase Sid1\tK08838 STK24_25_MST4; serine\/threonine-protein kinase 24\/25\/MST4 [EC:2.7.11.1]"
				},
				{
					"name":"2543111 ndk1; nucleoside diphosphate kinase Ndk1\tK00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]"
				},
				{
					"name":"2540792 kin1; MARK\/PAR-1 kinase Kin1\tK19852 KIN1_2; serine\/threonine protein kinase KIN1\/2 [EC:2.7.11.1]"
				}
				]
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"2542523 ncs1; calcium-binding protein\tK19932 NCS1; neuronal calcium sensor"
				}
				]
			}
			]
		},
		{
			"name":"Small GTPases and associated proteins",
			"children":[
			{
				"name":"Rab GTPases",
				"children":[
				{
					"name":"2543280 ypt2; GTPase Ypt2\tK07901 RAB8A; Ras-related protein Rab-8A"
				}
				]
			},
			{
				"name":"Rab associated proteins",
				"children":[
				{
					"name":"2542611 cam2; myosin I light chain Cam2\tK02183 CALM; calmodulin"
				},
				{
					"name":"2543039 cam1; calmodulin Cam1\tK02183 CALM; calmodulin"
				},
				{
					"name":"2541930 sec2; guanyl-nucleotide exchange factor Sec2\tK19940 SEC2; Rab guanine nucleotide exchange factor SEC2"
				},
				{
					"name":"2538850 sec1; SNARE-binding protein Sec1\tK15292 STXBP1; syntaxin-binding protein 1"
				},
				{
					"name":"2542372 sro7; Lgl family protein\tK08518 STXBP5; syntaxin-binding protein 5"
				},
				{
					"name":"2540823 dss4; guanyl-nucleotide exchange factor\tK19952 RABIF; guanine nucleotide exchange factor"
				},
				{
					"name":"2539298 gyp3; GTPase-activating protein Gyp3\tK19953 GRTP1; TBC1 domain family member 6"
				},
				{
					"name":"2540535 SPOM_SPBC215.01; GTPase-activating protein\tK19951 TBC1D8_9; TBC1 domain family member 8\/9"
				},
				{
					"name":"2541112 pex5; peroxisomal targeting signal receptor Pex5\tK13342 PEX5; peroxin-5"
				},
				{
					"name":"2539612 mrs6; Rab geranylgeranyltransferase escort protein\tK23460 CHM; Rab proteins geranylgeranyltransferase component A"
				},
				{
					"name":"2539343 bet4; Rab geranylgeranyltransferase alpha subunit\tK14050 RABGGTA; geranylgeranyl transferase type-2 subunit alpha [EC:2.5.1.60]"
				},
				{
					"name":"2543284 ptb1; geranylgeranyltransferase type 2 beta subunit Ptb1\tK05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]"
				},
				{
					"name":"2539705 rav1; RAVE complex subunit Rav1\tK24155 DMXL; rabconnectin-3a"
				}
				]
			},
			{
				"name":"Rho GTPases",
				"children":[
				{
					"name":"2543027 cdc42; Rho family GTPase Cdc42\tK04393 CDC42; cell division control protein 42"
				}
				]
			},
			{
				"name":"Other small GTPases and associated proteins"
			}
			]
		},
		{
			"name":"Tethering complex",
			"children":[
			{
				"name":"Exocyst complex",
				"children":[
				{
					"name":"2538952 sec6; exocyst complex subunit Exo3\tK06110 EXOC3; exocyst complex component 3"
				},
				{
					"name":"2539407 sec8; exocyst complex subunit Exo4\tK06111 EXOC4; exocyst complex component 4"
				},
				{
					"name":"2542843 sec10; exocyst complex subunit Sec10\tK19984 EXOC5; exocyst complex component 5"
				},
				{
					"name":"2538937 sec15; exocyst complex subunit Sec15\tK19985 EXOC6; exocyst complex component 6"
				},
				{
					"name":"2540127 exo70; exocyst complex subunit Exo70\tK07195 EXOC7; exocyst complex component 7"
				}
				]
			},
			{
				"name":"Exocyst complex assembly proteins",
				"children":[
				{
					"name":"2543058 dss1; proteasome receptor\/ubiquitin ligase adaptor Dss1\tK10881 SHFM1; 26 proteasome complex subunit DSS1"
				},
				{
					"name":"2541940 cdc8; tropomyosin\tK17945 TPM1_2; tropomyosin, fungi type"
				}
				]
			}
			]
		},
		{
			"name":"Others",
			"children":[
			{
				"name":"Exomer complex",
				"children":[
				{
					"name":"2541978 cfr1; CHS5-like protein Cfr1\tK19877 CHS5; chitin biosynthesis protein CHS5"
				},
				{
					"name":"2540240 bch1; ChAPs family protein\tK19881 BUD7; Chs5-Arf1p-binding protein BUD7\/BCH1"
				}
				]
			},
			{
				"name":"ER-PM contacts associated proteins",
				"children":[
				{
					"name":"2539288 tcb1; tricalbin, C2 domain protein (phospholipid binding) ER-plasma membrane tethering protein Tcb1\tK28063 ESYT; extended synaptotagmin"
				},
				{
					"name":"2539477 tcb2; tricalbin, C2 domain protein (phospholipid binding) ER-plasma membrane tethering protein Tcb2\tK28063 ESYT; extended synaptotagmin"
				},
				{
					"name":"2542267 tcb3; tricalbin\tK28063 ESYT; extended synaptotagmin"
				},
				{
					"name":"2540009 scs2; VAP family protein\tK29085 SCS2_22; vesicle-associated membrane protein-associated protein"
				},
				{
					"name":"2542179 scs22; VAMP\/synaptobrevin-associated protein family protein\tK29085 SCS2_22; vesicle-associated membrane protein-associated protein"
				}
				]
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"2542423 pep7; FYVE tethering component Pep7\tK12481 RBSN; rabenosyn-5"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"SNARE",
		"children":[
		{
			"name":"Syntaxin (Qa)",
			"children":[
			{
				"name":"Stx-PM",
				"children":[
				{
					"name":"2539377 psy1; plasma membrane SNARE Psy1\tK08486 STX1B_2_3; syntaxin 1B\/2\/3"
				}
				]
			},
			{
				"name":"Stx-Endo"
			},
			{
				"name":"Stx-TGN \/ EE",
				"children":[
				{
					"name":"2543436 tlg2; SNARE protein Tlg2\tK08489 STX16; syntaxin 16"
				}
				]
			},
			{
				"name":"Stx-cisGolgi",
				"children":[
				{
					"name":"2541263 sed5; SNARE protein Sed5\tK08490 STX5; syntaxin 5"
				}
				]
			},
			{
				"name":"Stx-sER"
			},
			{
				"name":"Stx-rER",
				"children":[
				{
					"name":"2538886 ufe1; SNARE protein Ufe1\tK08492 STX18; syntaxin 18"
				}
				]
			}
			]
		},
		{
			"name":"SNAP-25[N] (Qb)",
			"children":[
			{
				"name":"Vti1",
				"children":[
				{
					"name":"2540970 vti1; SNARE protein Vti1\tK08493 VTI1; vesicle transport through interaction with t-SNAREs 1"
				}
				]
			},
			{
				"name":"NPSN"
			},
			{
				"name":"Gos1 (Gos28)",
				"children":[
				{
					"name":"2542969 gos1; SNARE protein Gos1\tK08495 GOSR1; golgi SNAP receptor complex member 1"
				}
				]
			},
			{
				"name":"Bos1 \/ Membrin",
				"children":[
				{
					"name":"2541965 bos1; SNARE protein Bos1\tK08496 GOSR2; golgi SNAP receptor complex member 2"
				}
				]
			},
			{
				"name":"Sec20",
				"children":[
				{
					"name":"2541996 sec20; SNARE protein Sec20\tK08497 SEC20; protein transport protein SEC20"
				}
				]
			}
			]
		},
		{
			"name":"SNAP-25[C] (Qc)",
			"children":[
			{
				"name":"STX6",
				"children":[
				{
					"name":"2540973 tlg1; SNARE protein Tgl1\tK08499 TLG1; member of the syntaxin family of t-SNAREs"
				}
				]
			},
			{
				"name":"STX8",
				"children":[
				{
					"name":"2542946 fsv1; SNARE Stx8\tK08501 STX8; syntaxin 8"
				},
				{
					"name":"2538847 vsl1; SNARE protein Vam7\tK08502 VAM7; regulator of vacuolar morphogenesis"
				}
				]
			},
			{
				"name":"STX10"
			},
			{
				"name":"Bet1",
				"children":[
				{
					"name":"2542068 bet1; SNARE protein Bet1\tK08504 BET1; blocked early in transport 1"
				}
				]
			},
			{
				"name":"Sft1",
				"children":[
				{
					"name":"2542585 sft1; SNARE protein Sft1\tK08505 SFT1; protein transport protein SFT1"
				}
				]
			},
			{
				"name":"Syp7"
			},
			{
				"name":"Use1"
			}
			]
		},
		{
			"name":"SNAP-25 (Qb,c)",
			"children":[
			{
				"name":"SNAP-23"
			},
			{
				"name":"SNAP-25",
				"children":[
				{
					"name":"2540623 sec9; protein transport protein\tK19950 SEC9; protein transport protein SEC9"
				}
				]
			},
			{
				"name":"SNAP-29"
			},
			{
				"name":"SNAP-47"
			}
			]
		},
		{
			"name":"VAMP, Ykt6, Sec22 (R)",
			"children":[
			{
				"name":"VAMP",
				"children":[
				{
					"name":"2541731 syb1; synaptobrevin family receptor\tK08513 VAMP4; vesicle-associated membrane protein 4"
				}
				]
			},
			{
				"name":"Ykt6",
				"children":[
				{
					"name":"2539873 ykt6; SNARE protein Ykt6\tK08516 YKT6; synaptobrevin homolog YKT6"
				}
				]
			},
			{
				"name":"Sec22",
				"children":[
				{
					"name":"2540308 sec22; SNARE protein Sec22\tK08517 SEC22; vesicle transport protein SEC22"
				}
				]
			},
			{
				"name":"Tomosyn",
				"children":[
				{
					"name":"2542372 sro7; Lgl family protein\tK08518 STXBP5; syntaxin-binding protein 5"
				}
				]
			},
			{
				"name":"Putative SNAREs"
			}
			]
		},
		{
			"name":"SNARE associated proteins",
			"children":[
			{
				"name":"Syntaxin-binding proteins",
				"children":[
				{
					"name":"2538850 sec1; SNARE-binding protein Sec1\tK15292 STXBP1; syntaxin-binding protein 1"
				},
				{
					"name":"2539096 sly1; SNARE-binding protein Sly1\tK19998 SCFD1; sec1 family domain-containing protein 1"
				}
				]
			},
			{
				"name":"Palmitoyltransferases",
				"children":[
				{
					"name":"2539719 swf1; palmitoyltransferase Swf1\tK20003 ZDHHC4; palmitoyltransferase ZDHHC4 [EC:2.3.1.225]"
				},
				{
					"name":"2541757 akr1; palmitoyltransferase Akr1\tK20032 ZDHHC13_17; palmitoyltransferase ZDHHC13\/17 [EC:2.3.1.225]"
				}
				]
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"2542410 sec18; secretory pathway protein Sec18\tK06027 NSF; vesicle-fusing ATPase [EC:3.6.4.6]"
				},
				{
					"name":"2543488 sec17; alpha SNAP\tK15296 NAPA; alpha-soluble NSF attachment protein"
				},
				{
					"name":"2542427 atg24; autophagy associated protein Atg24\tK17919 SNX4; sorting nexin-4"
				},
				{
					"name":"2539722 snx41; sorting nexin Snx41\tK21996 SNX41_42; sorting nexin-41\/42"
				},
				{
					"name":"3361544 gpp74; golgi phosphoprotein 3\tK15620 GOLPH3; golgi phosphoprotein 3"
				},
				{
					"name":"2542744 cdc48; AAA family ATPase involved in ubiquitin-mediated protein degradation Cdc48\tK13525 VCP; transitional endoplasmic reticulum ATPase"
				},
				{
					"name":"2543170 ubx3; UBX domain-containing protein Ubx3\tK14012 NSFL1C; UBX domain-containing protein 1"
				},
				{
					"name":"2540161 vts1; RNA hairpin-binding protein\tK27407 VTS1; RNA-binding protein VTS1"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Endocytosis",
		"children":[
		{
			"name":"Clathrin-mediated endocytosis",
			"children":[
			{
				"name":"Clathrin",
				"children":[
				{
					"name":"2542078 chc1; clathrin heavy chain Chc1\tK04646 CLTC; clathrin heavy chain"
				}
				]
			},
			{
				"name":"Dynamin",
				"children":[
				{
					"name":"2540159 dnm1; mitochondrial dynamin family scission GTPase Dnm1\tK17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]"
				}
				]
			},
			{
				"name":"AP-2 complex",
				"children":[
				{
					"name":"2541162 apl3; AP-2 adaptor complex subunit Alp3\tK11824 AP2A; AP-2 complex subunit alpha"
				},
				{
					"name":"2541527 apm4; AP-2 adaptor complex subunit Apm4\tK11826 AP2M1; AP-2 complex subunit mu-1"
				},
				{
					"name":"2541086 aps2; AP-2 adaptor complex subunit Aps2\tK11827 AP2S1; AP-2 complex subunit sigma-1"
				}
				]
			},
			{
				"name":"Other core components",
				"children":[
				{
					"name":"2540862 syp1; cytoskeletal protein Syp1\tK20042 FCHO; F-BAR domain only protein"
				},
				{
					"name":"2539390 ent1; epsin\tK12471 EPN; epsin"
				},
				{
					"name":"2539421 ent3; ENTH\/VHS domain-containing protein Ent3\tK12471 EPN; epsin"
				},
				{
					"name":"2540824 ede1; EPS15 repeat-containing family actin cortical patch component protein\tK12472 EPS15; epidermal growth factor receptor substrate 15"
				},
				{
					"name":"2540702 yap18; ENTH\/VHS domain protein\tK20044 PICALM; phosphatidylinositol-binding clathrin assembly protein"
				},
				{
					"name":"2540633 hob1; BAR adaptor protein Hob1\tK12562 AMPH; amphiphysin"
				},
				{
					"name":"2542338 shd1; Sla1 family protein Shd1\tK20046 SLA1; actin cytoskeleton-regulatory complex protein SLA1"
				},
				{
					"name":"5802955 pan1; actin cortical patch component protein PanI\tK20047 PAN1; actin cytoskeleton-regulatory complex protein PAN1"
				},
				{
					"name":"2539902 end3; actin cortical patch component End3\tK20048 END3; actin cytoskeleton-regulatory complex protein END3"
				},
				{
					"name":"2539225 ssa2; heat shock protein Ssa2\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"2540199 sks2; ribosome-associated molecular chaperone Sks2\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"2542875 ssa1; heat shock protein Ssa1\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				}
				]
			},
			{
				"name":"Low-density lipoprotein receptor (LDLR) family proteins"
			},
			{
				"name":"LDLR adaptor proteins",
				"children":[
				{
					"name":"2542231 its3; 1-phosphatidylinositol-4-phosphate 5-kinase Its3\tK00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]"
				}
				]
			},
			{
				"name":"GPCR adaptor proteins",
				"children":[
				{
					"name":"2540833 any1; arrestin-related substrate adaptor Any1\tK20059 LDB19; arrestin-related trafficking adapter 1"
				},
				{
					"name":"2542260 any2; arrestin-related substrate adaptor Any2\tK20059 LDB19; arrestin-related trafficking adapter 1"
				},
				{
					"name":"2540410 aly2; arrestin Aly1-like protein\tK20061 ALY1_2; arrestin-related trafficking adapter 3\/6"
				},
				{
					"name":"2541205 aly1; arrestin-related trafficking adapter\tK20061 ALY1_2; arrestin-related trafficking adapter 3\/6"
				},
				{
					"name":"2539284 aly3; arrestin-related substrate adaptor Aly3\tK20062 ART4_5_7; arrestin-related trafficking adapter 4\/5\/7"
				},
				{
					"name":"2542940 rod1; arrestin\/PY protein 1\tK20062 ART4_5_7; arrestin-related trafficking adapter 4\/5\/7"
				}
				]
			},
			{
				"name":"Receptor tyrosine kinase (RTK) adaptor proteins"
			},
			{
				"name":"Inositol 5-phosphatases",
				"children":[
				{
					"name":"2540270 syj1; inositol-1,4,5-trisphosphate 5-phosphatase 1\tK20279 SYNJ; synaptojanin [EC:3.1.3.36]"
				},
				{
					"name":"2541098 syj2; inositol-1,4,5-trisphosphate 5-phosphatase 2\tK20279 SYNJ; synaptojanin [EC:3.1.3.36]"
				}
				]
			},
			{
				"name":"Kinases",
				"children":[
				{
					"name":"2539030 ppk38; Ark1\/Prk1 family protein kinase Ppk38\tK08853 AAK; AP2-associated kinase [EC:2.7.11.1]"
				},
				{
					"name":"2541109 ppk30; Ark1\/Prk1 family protein kinase Ppk30\tK08853 AAK; AP2-associated kinase [EC:2.7.11.1]"
				},
				{
					"name":"2541327 ppk32; serine\/threonine protein kinase Ppk32\tK17541 SCYL2; SCY1-like protein 2"
				}
				]
			},
			{
				"name":"Ubiquitin E3 ligases",
				"children":[
				{
					"name":"2539956 pub3; HECT-type ubiquitin-protein ligase Pub3\tK10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]"
				},
				{
					"name":"2541818 pub1; HECT-type ubiquitin-protein ligase E3 Pub1\tK10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]"
				},
				{
					"name":"2542432 pub2; HECT-type ubiquitin-protein ligase E3 Pub2\tK10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]"
				}
				]
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"2543336 end4; clathrin adaptor End4\tK20040 HIP1R; huntingtin-interacting protein 1-related protein"
				},
				{
					"name":"2543041 cnx1; calnexin Cnx1\tK08054 CANX; calnexin"
				}
				]
			}
			]
		},
		{
			"name":"Lipid raft mediated endocytosis",
			"children":[
			{
				"name":"Caveolin-mediated endocytosis",
				"children":[
				{
					"name":"2540159 dnm1; mitochondrial dynamin family scission GTPase Dnm1\tK17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]"
				},
				{
					"name":"2539649 pck2; protein kinase C (PKC)-like Pck2\tK02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]"
				},
				{
					"name":"2542293 pck1; protein kinase C (PKC)-like Pck1\tK02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]"
				}
				]
			},
			{
				"name":"Flotillin-dependent endocytosis"
			},
			{
				"name":"GRAF1-dependent endocytosis",
				"children":[
				{
					"name":"2543027 cdc42; Rho family GTPase Cdc42\tK04393 CDC42; cell division control protein 42"
				},
				{
					"name":"2540899 arf1; ADP-ribosylation factor-like protein Arf1\tK07937 ARF1_2; ADP-ribosylation factor 1\/2"
				}
				]
			},
			{
				"name":"Arf6-dependent endocytosis",
				"children":[
				{
					"name":"2539937 arf6; ADP-ribosylation factor-like protein Arf6\tK07941 ARF6; ADP-ribosylation factor 6"
				}
				]
			},
			{
				"name":"RhoA-dependent endocytosis",
				"children":[
				{
					"name":"2541612 rho1; Rho family GTPase Rho1\tK04513 RHOA; Ras homolog gene family, member A"
				},
				{
					"name":"2542013 rho5; Rho family GTPase Rho5\tK04513 RHOA; Ras homolog gene family, member A"
				},
				{
					"name":"2540159 dnm1; mitochondrial dynamin family scission GTPase Dnm1\tK17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]"
				}
				]
			}
			]
		},
		{
			"name":"Phagocytosis",
			"children":[
			{
				"name":"Fc receptors"
			},
			{
				"name":"Integrins (complement receptors)"
			},
			{
				"name":"Opsonins"
			},
			{
				"name":"Toll-like receptors"
			},
			{
				"name":"C-lectin receptors"
			},
			{
				"name":"Scavenger receptors"
			},
			{
				"name":"Coronins"
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"2539659 myo1; myosin I myo1\tK10356 MYO1; myosin I"
				}
				]
			}
			]
		},
		{
			"name":"Macropinocytosis",
			"children":[
			{
				"name":"Ras GTPases",
				"children":[
				{
					"name":"2542285 ras1; GTPase Ras1\tK07827 KRAS; GTPase KRas"
				},
				{
					"name":"2543027 cdc42; Rho family GTPase Cdc42\tK04393 CDC42; cell division control protein 42"
				}
				]
			},
			{
				"name":"Kinases",
				"children":[
				{
					"name":"2543444 pik3; phosphatidylinositol 3-kinase Pik3\tK00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]"
				},
				{
					"name":"2541154 fab1; 1-phosphatidylinositol-3-phosphate 5-kinase Fab1\tK00921 PIKFYVE; 1-phosphatidylinositol-3-phosphate 5-kinase [EC:2.7.1.150]"
				},
				{
					"name":"2539997 shk1; PAK-like kinase Shk1\tK04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]"
				}
				]
			},
			{
				"name":"Phospholipase C",
				"children":[
				{
					"name":"2541439 plc1; phosphoinositide phospholipase C Plc1\tK05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]"
				}
				]
			},
			{
				"name":"Sorting nexins",
				"children":[
				{
					"name":"2539552 vps5; retromer complex subunit Vps5\tK17917 SNX1_2; sorting nexin-1\/2"
				}
				]
			},
			{
				"name":"Others"
			}
			]
		},
		{
			"name":"Bin\/Amphiphysin\/Rvs (BAR) family proteins",
			"children":[
			{
				"name":"N-BAR proteins",
				"children":[
				{
					"name":"2540633 hob1; BAR adaptor protein Hob1\tK12562 AMPH; amphiphysin"
				},
				{
					"name":"2541160 hob3; BAR adaptor protein Hob3\tK20120 BIN3; bridging integrator 3"
				}
				]
			},
			{
				"name":"F-BAR proteins",
				"children":[
				{
					"name":"2539679 bzz1; diacylglycerol-binding protein Bzz1\tK20121 FNBP1; formin-binding protein 1"
				},
				{
					"name":"2540862 syp1; cytoskeletal protein Syp1\tK20042 FCHO; F-BAR domain only protein"
				},
				{
					"name":"2540635 rga7; Rho-type GTPase-activating protein Rga7\tK20643 RGD1; Rho GTPase-activating protein RGD1"
				}
				]
			},
			{
				"name":"I-BAR proteins"
			}
			]
		},
		{
			"name":"Rab GTPases and associated proteins",
			"children":[
			{
				"name":"Rab GTPases",
				"children":[
				{
					"name":"2542248 ypt5; GTPase Ypt5\tK07888 RAB5B; Ras-related protein Rab-5B"
				}
				]
			},
			{
				"name":"Rab associated proteins",
				"children":[
				{
					"name":"2540886 vps901; putative guanyl-nucleotide exchange factor Vps901\tK20131 RABGEF1; Rab5 GDP\/GTP exchange factor"
				},
				{
					"name":"2542423 pep7; FYVE tethering component Pep7\tK12481 RBSN; rabenosyn-5"
				},
				{
					"name":"2543444 pik3; phosphatidylinositol 3-kinase Pik3\tK00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]"
				},
				{
					"name":"2539996 vps15; serine\/threonine protein kinase Vps15\tK08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]"
				},
				{
					"name":"2541485 vps45; vacuolar sorting protein Vps45\tK12479 VPS45; vacuolar protein sorting-associated protein 45"
				}
				]
			}
			]
		},
		{
			"name":"Arf GTPases and associated proteins",
			"children":[
			{
				"name":"Arf GTPases",
				"children":[
				{
					"name":"2540899 arf1; ADP-ribosylation factor-like protein Arf1\tK07937 ARF1_2; ADP-ribosylation factor 1\/2"
				},
				{
					"name":"2539937 arf6; ADP-ribosylation factor-like protein Arf6\tK07941 ARF6; ADP-ribosylation factor 6"
				}
				]
			},
			{
				"name":"Arf associated proteins",
				"children":[
				{
					"name":"2542671 SPOM_SPAC824.09C; GTPase-activating protein\tK12486 SMAP; stromal membrane-associated protein"
				}
				]
			}
			]
		},
		{
			"name":"Others",
			"children":[
			{
				"name":"Fucosyltransferase"
			},
			{
				"name":"EFR3-PI4KIII alpha complex and associated proteins",
				"children":[
				{
					"name":"2540883 stt4; 1-phosphatidylinositol 4-kinase Stt4\tK00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]"
				},
				{
					"name":"2538740 efr3; protein efr3\tK21842 EFR3; protein EFR3"
				},
				{
					"name":"2543221 ypp1; cargo transport protein Ypp1\tK21845 YPP1; cargo-transport protein YPP1"
				}
				]
			},
			{
				"name":"Insulin-like growth factor-binding proteins"
			},
			{
				"name":"Others"
			}
			]
		}
		]
	},
	{
		"name":"Endosome - Lysosome transport",
		"children":[
		{
			"name":"Rab GTPases and associated proteins",
			"children":[
			{
				"name":"Rab GTPases",
				"children":[
				{
					"name":"2542248 ypt5; GTPase Ypt5\tK07888 RAB5B; Ras-related protein Rab-5B"
				},
				{
					"name":"2540763 ypt7; GTPase Ypt7\tK07897 RAB7A; Ras-related protein Rab-7A [EC:3.6.5.2]"
				},
				{
					"name":"2543411 ypt71; GTPase Ypt71\tK07897 RAB7A; Ras-related protein Rab-7A [EC:3.6.5.2]"
				}
				]
			},
			{
				"name":"FTS\/Hook\/FHIP (FHF) complex"
			},
			{
				"name":"FERRY complex"
			},
			{
				"name":"Rab associated proteins",
				"children":[
				{
					"name":"2542072 bop1; ubiquitin-protein ligase E3\tK11982 RNF115_126; E3 ubiquitin-protein ligase RNF115\/126 [EC:2.3.2.27]"
				},
				{
					"name":"2543444 pik3; phosphatidylinositol 3-kinase Pik3\tK00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]"
				},
				{
					"name":"2540175 pre6; 20S proteasome complex subunit alpha 4 Pre6\tK02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]"
				},
				{
					"name":"2543609 gyp7; GTPase-activating protein Gyp7\tK20168 TBC1D15; TBC1 domain family member 15"
				},
				{
					"name":"2539612 mrs6; Rab geranylgeranyltransferase escort protein\tK23460 CHM; Rab proteins geranylgeranyltransferase component A"
				},
				{
					"name":"2539343 bet4; Rab geranylgeranyltransferase alpha subunit\tK14050 RABGGTA; geranylgeranyl transferase type-2 subunit alpha [EC:2.5.1.60]"
				},
				{
					"name":"2543284 ptb1; geranylgeranyltransferase type 2 beta subunit Ptb1\tK05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]"
				},
				{
					"name":"2543572 SPOM_SPAC4G8.04; GTPase-activating protein\tK20176 SGSM3; small G protein signaling modulator 3"
				},
				{
					"name":"3361544 gpp74; golgi phosphoprotein 3\tK15620 GOLPH3; golgi phosphoprotein 3"
				}
				]
			}
			]
		},
		{
			"name":"Arf GTPases and associated proteins",
			"children":[
			{
				"name":"Arf GTPases"
			},
			{
				"name":"BLOC-one-related complex (BORC)"
			},
			{
				"name":"N-acetyl transferase complex C (NatC)",
				"children":[
				{
					"name":"2539835 naa30; NatC N-acetyltransferase complex catalytic subunit Naa30\tK00670 NAA30; N-alpha-acetyltransferase 30 [EC:2.3.1.256]"
				},
				{
					"name":"2539689 naa35; NatC N-acetyltransferase complex subunit Mak10\tK20823 NAA35; N-alpha-acetyltransferase 35, NatC auxiliary subunit"
				},
				{
					"name":"2541272 naa38; putative NatC N-acetyltransferase non-catalytic subunit Naa38\tK20824 NAA38; N-alpha-acetyltransferase 38, NatC auxiliary subunit"
				}
				]
			},
			{
				"name":"Other Arf associated proteins"
			}
			]
		},
		{
			"name":"Endosomal sorting complexes required for transport (ESCRT)",
			"children":[
			{
				"name":"ESCRT-0 complex",
				"children":[
				{
					"name":"2542403 sst4; ESCRT 0 complex subunit sst4\tK12182 HGS; hepatocyte growth factor-regulated tyrosine kinase substrate"
				},
				{
					"name":"2540055 hse1; ESCRT-0 subunit protein HSE1\tK04705 STAM; signal transducing adaptor molecule"
				}
				]
			},
			{
				"name":"ESCRT-I complex",
				"children":[
				{
					"name":"2542429 vps28; ESCRT I complex subunit Vps28\tK12184 VPS28; ESCRT-I complex subunit VPS28"
				}
				]
			},
			{
				"name":"ESCRT-II complex",
				"children":[
				{
					"name":"2541147 dot2; ESCRT II complex subunit Dot2\tK12188 SNF8; ESCRT-II complex subunit VPS22"
				},
				{
					"name":"2540828 vps25; ESCRT II complex subunit Vps25\tK12189 VPS25; ESCRT-II complex subunit VPS25"
				},
				{
					"name":"2540981 vps36; ESCRT II complex subunit Vps36\tK12190 VPS36; ESCRT-II complex subunit VPS36"
				}
				]
			},
			{
				"name":"ESCRT-III complex",
				"children":[
				{
					"name":"2539670 did2; ESCRT III complex subunit Did2\tK12197 CHMP1; charged multivesicular body protein 1"
				},
				{
					"name":"2543521 did4; ESCRT III complex subunit Did4\tK12191 CHMP2A; charged multivesicular body protein 2A"
				},
				{
					"name":"2542234 vps24; ESCRT III complex subunit Vps24\tK12193 VPS24; charged multivesicular body protein 3"
				},
				{
					"name":"2542922 vps32; ESCRT III complex subunit Vps32\tK12194 CHMP4A_B; charged multivesicular body protein 4A\/B"
				},
				{
					"name":"2538774 vps60; sorting protein Vps60\tK12198 CHMP5; charged multivesicular body protein 5"
				},
				{
					"name":"2540725 vps20; ESCRT III complex subunit Vps20\tK12195 CHMP6; charged multivesicular body protein 6"
				},
				{
					"name":"2539983 cmp7; ESCRT III complex subunit\tK15053 CHMP7; charged multivesicular body protein 7"
				},
				{
					"name":"2542054 vps4; AAA family ATPase Vps4\tK12196 VPS4; vacuolar protein-sorting-associated protein 4"
				}
				]
			},
			{
				"name":"ESCRT associated proteins",
				"children":[
				{
					"name":"2541947 alx1; BRO1 domain-containing protein\tK12200 PDCD6IP; programmed cell death 6-interacting protein"
				}
				]
			}
			]
		},
		{
			"name":"Tethering complex",
			"children":[
			{
				"name":"CORVET complex",
				"children":[
				{
					"name":"2539519 vps3; GTPase regulator Vps3\tK20177 VPS3; vacuolar protein sorting-associated protein 3"
				},
				{
					"name":"2542136 vps8; WD repeat-containing protein Vps8\tK20178 VPS8; vacuolar protein sorting-associated protein 8"
				},
				{
					"name":"2542307 SPOM_SPAC16A10.03C; Pep5\/Vps11-like zinc finger domain-containing protein\tK20179 VPS11; vacuolar protein sorting-associated protein 11"
				},
				{
					"name":"2543359 vps11; HOPs complex subunit Pep5\/Vps11\tK20179 VPS11; vacuolar protein sorting-associated protein 11"
				},
				{
					"name":"2541533 vps16; HOPS complex subunit Vps16\tK20180 VPS16; vacuolar protein sorting-associated protein 16"
				},
				{
					"name":"2539053 pep3; ubiquitin-protein ligase E3\tK20181 VPS18; vacuolar protein sorting-associated protein 18"
				},
				{
					"name":"2539880 vps33; HOPS\/CORVET complex subunit, vacuolar sorting protein Vps33\tK20182 VPS33A; vacuolar protein sorting-associated protein 33A"
				}
				]
			},
			{
				"name":"Hops complex",
				"children":[
				{
					"name":"2542307 SPOM_SPAC16A10.03C; Pep5\/Vps11-like zinc finger domain-containing protein\tK20179 VPS11; vacuolar protein sorting-associated protein 11"
				},
				{
					"name":"2543359 vps11; HOPs complex subunit Pep5\/Vps11\tK20179 VPS11; vacuolar protein sorting-associated protein 11"
				},
				{
					"name":"2541533 vps16; HOPS complex subunit Vps16\tK20180 VPS16; vacuolar protein sorting-associated protein 16"
				},
				{
					"name":"2539053 pep3; ubiquitin-protein ligase E3\tK20181 VPS18; vacuolar protein sorting-associated protein 18"
				},
				{
					"name":"2539880 vps33; HOPS\/CORVET complex subunit, vacuolar sorting protein Vps33\tK20182 VPS33A; vacuolar protein sorting-associated protein 33A"
				},
				{
					"name":"2541859 vam6; guanyl-nucleotide exchange factor Vam6\tK20183 VPS39; Vam6\/Vps39-like protein vacuolar protein sorting-associated protein 39"
				},
				{
					"name":"2542058 vps41; HOPS complex subunit Vps41\tK20184 VPS41; vacuolar protein sorting-associated protein 41"
				}
				]
			}
			]
		},
		{
			"name":"Acidification regulators",
			"children":[
			{
				"name":"Rabconnectin-3 complex",
				"children":[
				{
					"name":"2539705 rav1; RAVE complex subunit Rav1\tK24155 DMXL; rabconnectin-3a"
				}
				]
			},
			{
				"name":"RAVE complex",
				"children":[
				{
					"name":"2539705 rav1; RAVE complex subunit Rav1\tK24155 DMXL; rabconnectin-3a"
				},
				{
					"name":"2540917 skp1; SCF ubiquitin ligase complex subunit Skp1\tK03094 SKP1; S-phase kinase-associated protein 1"
				}
				]
			}
			]
		},
		{
			"name":"Others",
			"children":[
			{
				"name":"AP-3 complex",
				"children":[
				{
					"name":"2542857 apl5; AP-3 adaptor complex subunit Apl5\tK12396 AP3D; AP-3 complex subunit delta"
				},
				{
					"name":"2541771 apl6; AP-3 adaptor complex subunit Apl6\tK12397 AP3B; AP-3 complex subunit beta"
				},
				{
					"name":"2541119 apm3; AP-3 adaptor complex subunit Apm3\tK12398 AP3M; AP-3 complex subunit mu"
				},
				{
					"name":"2542114 aps3; AP-3 adaptor complex subunit Aps3\tK12399 AP3S; AP-3 complex subunit sigma"
				}
				]
			},
			{
				"name":"BLOC-1 complex"
			},
			{
				"name":"BLOC-1 complex (yeast)"
			},
			{
				"name":"BLOC-2 complex"
			},
			{
				"name":"BLOC-3 complex"
			},
			{
				"name":"Ferlins"
			},
			{
				"name":"Lysosomal membrane proteins",
				"children":[
				{
					"name":"2538749 SPOM_SPCC1672.11C; P-type ATPase P5 type\tK13526 ATP13A2; cation-transporting P-type ATPase 13A2 [EC:7.2.2.-]"
				},
				{
					"name":"2542076 cta5; Ca(2+)\/Mn(2+)-transporting P-type ATPase P5 type Cta5\tK13526 ATP13A2; cation-transporting P-type ATPase 13A2 [EC:7.2.2.-]"
				}
				]
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"2542459 aut12; autophagy associated protein Aut12\tK20195 MON1; vacuolar fusion protein MON1"
				},
				{
					"name":"2540837 ubp4; ubiquitin hydrolase Ubp4\tK11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]"
				},
				{
					"name":"2542606 sst2; AMSH-like ubiquitin-specific protease\tK11866 STAMBP; STAM-binding protein [EC:3.4.19.12]"
				},
				{
					"name":"2543247 vps55; protein Vps55\tK28212 LEPROT; OB-RGRP\/VPS55 family protein"
				},
				{
					"name":"2541244 vps68; sorting protein Vps68\tK29023 VPS68; vacuolar protein sorting-associated protein 68"
				},
				{
					"name":"2542724 vps1; dynamin family protein Vps1\tK23481 VPS1; vacuolar protein sorting-associated protein 1"
				},
				{
					"name":"2540571 lvs1; beige protein 1\tK24781 BPH1; beige protein homolog 1"
				},
				{
					"name":"2539213 ear1; SPRY domain membrane protein, specificity factor required for ubiquitination Ear1\tK28544 SSH4; SSH4 family protein"
				},
				{
					"name":"2540811 rcr1; protein Rcr1\tK28545 RCR; protein RCR"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Protein recycling",
		"children":[
		{
			"name":"Rab GTPases and associated proteins",
			"children":[
			{
				"name":"Rab GTPases",
				"children":[
				{
					"name":"2542113 ypt4; GTPase Ypt4\tK07880 RAB4B; Ras-related protein Rab-4B"
				},
				{
					"name":"2542219 ypt3; Rab11 family GTPase Ypt3\tK07904 RAB11A; Ras-related protein Rab-11A"
				}
				]
			},
			{
				"name":"Rab4 associated proteins",
				"children":[
				{
					"name":"2542423 pep7; FYVE tethering component Pep7\tK12481 RBSN; rabenosyn-5"
				},
				{
					"name":"2542427 atg24; autophagy associated protein Atg24\tK17919 SNX4; sorting nexin-4"
				}
				]
			},
			{
				"name":"Rab11 associated proteins",
				"children":[
				{
					"name":"2543641 wdr44; WD repeat-containing protein\tK20241 WDR44; WD repeat-containing protein 44"
				},
				{
					"name":"2540716 sec13; GATOR2-SEACAT complex\/COPII-coated vesicle component\/nuclear pore outer ring WD repeat protein Sec13\tK14004 SEC13; protein transport protein SEC13"
				},
				{
					"name":"2538937 sec15; exocyst complex subunit Sec15\tK19985 EXOC6; exocyst complex component 6"
				},
				{
					"name":"3361544 gpp74; golgi phosphoprotein 3\tK15620 GOLPH3; golgi phosphoprotein 3"
				}
				]
			},
			{
				"name":"Other Rab GTPase associated proteins",
				"children":[
				{
					"name":"2540886 vps901; putative guanyl-nucleotide exchange factor Vps901\tK20131 RABGEF1; Rab5 GDP\/GTP exchange factor"
				},
				{
					"name":"2543580 rad51; RecA family recombinase Rad51\/Rhp51\tK04482 RAD51; DNA repair protein RAD51"
				}
				]
			}
			]
		},
		{
			"name":"Others",
			"children":[
			{
				"name":"Glutamate receptor-interacting proteins (GRIPs)"
			},
			{
				"name":"GRIP associated proteins"
			},
			{
				"name":"EARP complex",
				"children":[
				{
					"name":"2540233 vps52; GARP complex subunit Vps52\tK20298 VPS52; vacuolar protein sorting-associated protein 52"
				},
				{
					"name":"2542930 vps53; GARP complex subunit Vps53\tK20299 VPS53; vacuolar protein sorting-associated protein 53"
				}
				]
			},
			{
				"name":"WASH complex",
				"children":[
				{
					"name":"2542679 acp1; F-actin-capping protein alpha subunit\tK10364 CAPZA; F-actin-capping protein subunit alpha"
				},
				{
					"name":"2543390 acp2; F-actin-capping protein beta subunit acp2\tK10365 CAPZB; F-actin-capping protein subunit beta"
				}
				]
			},
			{
				"name":"Retriever complex",
				"children":[
				{
					"name":"2542802 vps29; retromer complex subunit Vps29\tK18467 VPS29; vacuolar protein sorting-associated protein 29"
				}
				]
			},
			{
				"name":"CCC complex"
			},
			{
				"name":"Others"
			}
			]
		}
		]
	},
	{
		"name":"Endosome - Golgi transport",
		"children":[
		{
			"name":"Rab GTPases and associated proteins",
			"children":[
			{
				"name":"Rab GTPases",
				"children":[
				{
					"name":"2540763 ypt7; GTPase Ypt7\tK07897 RAB7A; Ras-related protein Rab-7A [EC:3.6.5.2]"
				},
				{
					"name":"2543411 ypt71; GTPase Ypt71\tK07897 RAB7A; Ras-related protein Rab-7A [EC:3.6.5.2]"
				}
				]
			},
			{
				"name":"Retromer subcomplex",
				"children":[
				{
					"name":"2539462 vps35; retromer complex subunit Vps35\tK18468 VPS35; vacuolar protein sorting-associated protein 35"
				},
				{
					"name":"2542802 vps29; retromer complex subunit Vps29\tK18467 VPS29; vacuolar protein sorting-associated protein 29"
				},
				{
					"name":"2543395 vps26; retromer complex arrestin related endocytic adaptor ubunit Vps26\tK18466 VPS26A_B; vacuolar protein sorting-associated protein 26A\/B"
				}
				]
			},
			{
				"name":"Rab associated proteins",
				"children":[
				{
					"name":"3361544 gpp74; golgi phosphoprotein 3\tK15620 GOLPH3; golgi phosphoprotein 3"
				},
				{
					"name":"2540535 SPOM_SPBC215.01; GTPase-activating protein\tK19951 TBC1D8_9; TBC1 domain family member 8\/9"
				},
				{
					"name":"2540516 vps1301; lipid transfer protein\tK19525 VPS13A_C; vacuolar protein sorting-associated protein 13A\/C"
				}
				]
			}
			]
		},
		{
			"name":"Arf GTPases and associated proteins",
			"children":[
			{
				"name":"Arf GTPases",
				"children":[
				{
					"name":"2540899 arf1; ADP-ribosylation factor-like protein Arf1\tK07937 ARF1_2; ADP-ribosylation factor 1\/2"
				}
				]
			},
			{
				"name":"Arf GTPase associated proteins",
				"children":[
				{
					"name":"2539181 SPOM_SPCC622.14; GTPase-activating protein\tK12492 ARFGAP1; ADP-ribosylation factor GTPase-activating protein 1"
				},
				{
					"name":"2541825 glo3; ARF GTPase-activating protein\tK12493 ARFGAP2_3; ADP-ribosylation factor GTPase-activating protein 2\/3"
				},
				{
					"name":"2542671 SPOM_SPAC824.09C; GTPase-activating protein\tK12486 SMAP; stromal membrane-associated protein"
				},
				{
					"name":"2539865 cnt5; centaurin Cnt5\tK12488 ASAP; Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein"
				},
				{
					"name":"2542107 sec72; Sec7 domain-containing protein sec72\tK18442 ARFGEF; brefeldin A-inhibited guanine nucleotide-exchange protein"
				},
				{
					"name":"2543610 sec71; Sec7 domain-containing protein sec71\tK18442 ARFGEF; brefeldin A-inhibited guanine nucleotide-exchange protein"
				},
				{
					"name":"2540746 gea1; guanyl-nucleotide exchange factor\tK18443 GBF1; golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1"
				}
				]
			}
			]
		},
		{
			"name":"Tethering complex",
			"children":[
			{
				"name":"Conserved oligomeric Golgi (COG) complex",
				"children":[
				{
					"name":"2539758 cog3; COG complex subunit Cog3\tK20290 COG3; conserved oligomeric Golgi complex subunit 3"
				},
				{
					"name":"2539017 cog4; COG complex subunit Cog4\tK20291 COG4; conserved oligomeric Golgi complex subunit 4"
				},
				{
					"name":"2541207 cog6; COG complex subunit Cog6\tK20293 COG6; conserved oligomeric Golgi complex subunit 6"
				},
				{
					"name":"2539796 cog8; COG complex subunit Cog8\tK20295 COG8; conserved oligomeric Golgi complex subunit 8"
				}
				]
			},
			{
				"name":"GARP complex",
				"children":[
				{
					"name":"2540233 vps52; GARP complex subunit Vps52\tK20298 VPS52; vacuolar protein sorting-associated protein 52"
				},
				{
					"name":"2542930 vps53; GARP complex subunit Vps53\tK20299 VPS53; vacuolar protein sorting-associated protein 53"
				},
				{
					"name":"2541725 vps54; GARP complex subunit Vps54\tK17600 VPS54; vacuolar protein sorting-associated protein 54"
				}
				]
			},
			{
				"name":"TRAPP complex II",
				"children":[
				{
					"name":"2543335 bet5; TRAPP complex subunit Bet5\tK20300 TRAPPC1; trafficking protein particle complex subunit 1"
				},
				{
					"name":"2539833 trs20; TRAPP complex subunit Trs20\tK20301 TRAPPC2; trafficking protein particle complex subunit 2"
				},
				{
					"name":"2542766 tca17; TRAPP complex subunit 2-like protein\tK20301 TRAPPC2; trafficking protein particle complex subunit 2"
				},
				{
					"name":"2543570 bet3; TRAPP complex subunit Bet3\tK20302 TRAPPC3; trafficking protein particle complex subunit 3"
				},
				{
					"name":"2540976 trs23; TRAPP complex subunit Trs23\tK20303 TRAPPC4; trafficking protein particle complex subunit 4"
				},
				{
					"name":"2540014 trs31; TRAPP complex subunit Trs31\tK20280 TRAPPC5; trafficking protein particle complex subunit 5"
				},
				{
					"name":"2542905 trs33; TRAPP complex subunit Trs33\tK20304 TRAPPC6; trafficking protein particle complex subunit 6"
				},
				{
					"name":"2539665 trs8501; TRAPP complex subunit Trs85\tK20305 TRAPPC8; trafficking protein particle complex subunit 8"
				},
				{
					"name":"2539876 SPOM_SPBC1734.07C; TRAPP III complex subunit Trs8502\tK20305 TRAPPC8; trafficking protein particle complex subunit 8"
				},
				{
					"name":"2542375 trs120; TRAPP complex subunit Trs120\tK20306 TRAPPC9; trafficking protein particle complex subunit 9"
				},
				{
					"name":"2538961 trs130; TRAPP complex subunit Trs130\tK20307 TRAPPC10; trafficking protein particle complex subunit 10"
				}
				]
			}
			]
		},
		{
			"name":"Others",
			"children":[
			{
				"name":"AP-1 complex",
				"children":[
				{
					"name":"2539311 apl4; AP-1 adaptor complex gamma subunit Apl4\tK12391 AP1G1; AP-1 complex subunit gamma-1"
				},
				{
					"name":"2541306 apm1; AP-1 adaptor complex mu subunit Apm1\tK12393 AP1M; AP-1 complex subunit mu"
				}
				]
			},
			{
				"name":"AP-3 complex",
				"children":[
				{
					"name":"2542857 apl5; AP-3 adaptor complex subunit Apl5\tK12396 AP3D; AP-3 complex subunit delta"
				},
				{
					"name":"2541771 apl6; AP-3 adaptor complex subunit Apl6\tK12397 AP3B; AP-3 complex subunit beta"
				},
				{
					"name":"2541119 apm3; AP-3 adaptor complex subunit Apm3\tK12398 AP3M; AP-3 complex subunit mu"
				},
				{
					"name":"2542114 aps3; AP-3 adaptor complex subunit Aps3\tK12399 AP3S; AP-3 complex subunit sigma"
				}
				]
			},
			{
				"name":"AP-4 complex"
			},
			{
				"name":"GGA",
				"children":[
				{
					"name":"2540570 gga22; adaptin\tK12404 GGA; ADP-ribosylation factor-binding protein GGA"
				}
				]
			},
			{
				"name":"Aftiphilin\/p200\/gamma-synergin complex"
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"2542065 pld1; phospholipase D Pld1\tK01115 PLD1_2; phospholipase D1\/2 [EC:3.1.4.4]"
				},
				{
					"name":"2540883 stt4; 1-phosphatidylinositol 4-kinase Stt4\tK00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]"
				},
				{
					"name":"2542231 its3; 1-phosphatidylinositol-4-phosphate 5-kinase Its3\tK00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]"
				},
				{
					"name":"2541154 fab1; 1-phosphatidylinositol-3-phosphate 5-kinase Fab1\tK00921 PIKFYVE; 1-phosphatidylinositol-3-phosphate 5-kinase [EC:2.7.1.150]"
				},
				{
					"name":"2542208 gdt2; GDT1-like protein\tK23541 TMEM165; Ca2+\/H+ antiporter, TMEM165\/GDT1 family"
				},
				{
					"name":"2543369 SPOM_SPAPB1A10.07C; sphingolipid biosynthesis protein\tK23544 SERINC1; serine incorporator 1"
				},
				{
					"name":"2541210 snx3; sorting nexin Snx3\tK17918 SNX3_12; sorting nexin-3\/12"
				},
				{
					"name":"2543124 mvp1; sorting nexin Mvp1\tK17922 SNX8; sorting nexin-8"
				},
				{
					"name":"2541486 SPOM_SPAC23D3.13C; guanyl-nucleotide exchange factor\tK26678 MON2; protein MON2"
				},
				{
					"name":"2543220 dop1; family protein DOPEY\tK26680 DOP1; protein dopey"
				},
				{
					"name":"2541539 SPOM_SPAP27G11.12; uncharacterized protein\tK27894 HID1; protein HID1"
				},
				{
					"name":"2542168 ftp105; Ubp5 interacting protein Ftp10\tK27894 HID1; protein HID1"
				},
				{
					"name":"2542733 tvp15; COPI-coated vesicle-associated protein\tK26750 TVP15; golgi apparatus membrane protein TVP15"
				},
				{
					"name":"2540256 SPOM_SPBC32F12.12C; golgi membrane protein involved in vesicle-mediated transport\tK26751 TVP18; golgi apparatus membrane protein TVP18"
				},
				{
					"name":"2540332 tvp23; putative transport protein Tvp23\tK26752 TVP23; golgi apparatus membrane protein TVP23"
				},
				{
					"name":"2539871 SPOM_SPBC1711.09C; SNARE-associated protein\tK26753 TVP38; golgi apparatus membrane protein TVP38"
				},
				{
					"name":"2542724 vps1; dynamin family protein Vps1\tK23481 VPS1; vacuolar protein sorting-associated protein 1"
				},
				{
					"name":"2539861 vps10; vacuolar protein sorting receptor vps10\tK28985 PEP1; vacuolar protein sorting\/targeting protein 10"
				},
				{
					"name":"2543324 vps17; retromer complex subunit Vps17\tK28986 VPS17; vacuolar protein sorting-associated protein 17"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Endoplasmic reticulum (ER) - Golgi transport",
		"children":[
		{
			"name":"Forward pathways",
			"children":[
			{
				"name":"Coat protein complex II (COP-II)",
				"children":[
				{
					"name":"2540439 sar1; ADP-ribosylation factor Sar1\tK07953 SAR1; GTP-binding protein SAR1 [EC:3.6.5.-]"
				},
				{
					"name":"2540716 sec13; GATOR2-SEACAT complex\/COPII-coated vesicle component\/nuclear pore outer ring WD repeat protein Sec13\tK14004 SEC13; protein transport protein SEC13"
				},
				{
					"name":"2541273 sec31; COPII-coated vesicle-associated protein Sec31\tK14005 SEC31; protein transport protein SEC31"
				},
				{
					"name":"2538699 sec231; COPII cargo receptor subunit Sec23a\tK14006 SEC23; protein transport protein SEC23"
				},
				{
					"name":"2541164 sec2302; COPII cargo receptor subunit Sec23b\tK14006 SEC23; protein transport protein SEC23"
				},
				{
					"name":"2540710 sfb3; COPII-coated vesicle-associated protein Sfb3\tK14007 SEC24; protein transport protein SEC24"
				},
				{
					"name":"2541601 sec24; coincidence detector Sec24\/Sfb2 subunit\tK14007 SEC24; protein transport protein SEC24"
				},
				{
					"name":"2540996 spo14; GDP\/GTP exchange factor Spo14\tK14003 PREB; prolactin regulatory element-binding protein"
				},
				{
					"name":"2542678 sec16; multidomain vesicle coat component Sec16\tK20353 SEC16; COPII coat assembly protein SEC16"
				}
				]
			},
			{
				"name":"TRAPP complex I",
				"children":[
				{
					"name":"2543335 bet5; TRAPP complex subunit Bet5\tK20300 TRAPPC1; trafficking protein particle complex subunit 1"
				},
				{
					"name":"2539833 trs20; TRAPP complex subunit Trs20\tK20301 TRAPPC2; trafficking protein particle complex subunit 2"
				},
				{
					"name":"2542766 tca17; TRAPP complex subunit 2-like protein\tK20301 TRAPPC2; trafficking protein particle complex subunit 2"
				},
				{
					"name":"2543570 bet3; TRAPP complex subunit Bet3\tK20302 TRAPPC3; trafficking protein particle complex subunit 3"
				},
				{
					"name":"2540976 trs23; TRAPP complex subunit Trs23\tK20303 TRAPPC4; trafficking protein particle complex subunit 4"
				},
				{
					"name":"2540014 trs31; TRAPP complex subunit Trs31\tK20280 TRAPPC5; trafficking protein particle complex subunit 5"
				},
				{
					"name":"2542905 trs33; TRAPP complex subunit Trs33\tK20304 TRAPPC6; trafficking protein particle complex subunit 6"
				}
				]
			},
			{
				"name":"p24 family proteins",
				"children":[
				{
					"name":"2540028 erp5; COPII-coated vesicle-associated protein Erp5\/Erp6\tK20346 TMED4_9_11; p24 family protein alpha"
				},
				{
					"name":"2539350 emp24; COPII-coated vesicle-associated protein Emp24\tK20347 TMED2; p24 family protein beta-1"
				},
				{
					"name":"2541782 erv25; COPII-coated vesicle-associated protein Erv25\tK20352 TMED10; p24 family protein delta-1"
				}
				]
			},
			{
				"name":"PDI family proteins",
				"children":[
				{
					"name":"2541460 pdi1; protein disulfide isomerase\tK09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]"
				},
				{
					"name":"2542270 pdi2; ER protein disulfide isomerase Pdi2\tK09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]"
				},
				{
					"name":"2542841 mpd1; thioredoxin family protein\tK09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]"
				}
				]
			},
			{
				"name":"Rab GTPases",
				"children":[
				{
					"name":"2539784 ypt1; GTPase Ypt1\tK07874 RAB1A; Ras-related protein Rab-1A"
				}
				]
			},
			{
				"name":"Rab associated proteins",
				"children":[
				{
					"name":"2539170 yip3; Rab GTPase-binding protein\tK20359 RABAC1; PRA1 family protein 1"
				},
				{
					"name":"2541149 gyp10; GTPase-activating protein Gyp10\tK20372 TBC1D20; TBC1 domain family member 20"
				},
				{
					"name":"2540892 gyp1; GTPase-activating protein Gyp1\tK20360 TBC1D22; TBC1 domain family member 2"
				},
				{
					"name":"2540356 hrf1; COPII-coated vesicle-associated protein Hrf1\tK20362 YIF1; protein transport protein YIF1"
				},
				{
					"name":"2542215 yos1; transport protein Yos1\tK22939 IER3IP1; immediate early response 3-interacting protein 1"
				},
				{
					"name":"2542708 uso1; ER to Golgi tether Uso1\tK20361 USO1; intracellular protein transport protein USO1"
				}
				]
			},
			{
				"name":"ER-Golgi intermediate compartment (ERGIC) proteins",
				"children":[
				{
					"name":"2538834 SPOM_SPCC126.08C; lectin family glycoprotein receptor\tK10082 LMAN2; lectin, mannose-binding 2"
				},
				{
					"name":"2541719 mns1; mannosyl-oligosaccharide 1,2-alpha-mannosidase\tK23741 MAN1B; endoplasmic reticulum Man9GlcNAc2 1,2-alpha-mannosidase [EC:3.2.1.209]"
				},
				{
					"name":"2540311 erv41; COPII-coated vesicle-associated protein Erv41\tK20366 ERGIC2; endoplasmic reticulum-Golgi intermediate compartment protein 2"
				},
				{
					"name":"2541538 erv46; COPII-coated vesicle-associated protein Erv46\tK20367 ERGIC3; endoplasmic reticulum-Golgi intermediate compartment protein 3"
				},
				{
					"name":"2542639 cor1; cornichon family protein\tK20368 CNIH; protein cornichon"
				},
				{
					"name":"2543081 erv14; cornichon family protein Erv14\tK20368 CNIH; protein cornichon"
				},
				{
					"name":"2539516 erv29; cargo receptor protein\tK20369 ERV29; ER-derived vesicles protein"
				},
				{
					"name":"2541815 bip1; ER heat shock protein BiP\tK09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:5.6.1.10]"
				},
				{
					"name":"2541774 rer1; Rer1 family protein\tK29081 RER1; Rer1 family protein"
				}
				]
			}
			]
		},
		{
			"name":"Retrieval pathways",
			"children":[
			{
				"name":"Coat protein complex I (COP-I)",
				"children":[
				{
					"name":"2541412 cop1; coatomer alpha subunit protein\tK05236 COPA; coatomer subunit alpha"
				},
				{
					"name":"2539798 sec26; coatomer beta subunit Sec26\tK17301 COPB1; coatomer subunit beta"
				},
				{
					"name":"2540050 sec27; coatomer beta' subunit protein\tK17302 COPB2; coatomer subunit beta'"
				},
				{
					"name":"2542247 sec21; coatomer gamma subunit Sec21\tK17267 COPG; coatomer subunit gamma"
				},
				{
					"name":"2538953 ret2; coatomer delta subunit Ret2\tK20471 COPD; coatomer subunit delta"
				},
				{
					"name":"2540317 sec28; coatomer epsilon subunit protein\tK17268 COPE; coatomer subunit epsilon"
				},
				{
					"name":"2539522 ret3; coatomer zeta subunit protein\tK20472 COPZ; coatomer subunit zeta"
				}
				]
			},
			{
				"name":"NRZ (DSL1) complex",
				"children":[
				{
					"name":"2541081 drp1; RINT1 family protein\tK20474 RINT1; RAD50-interacting protein 1"
				},
				{
					"name":"2541492 sec39; secretory pathway protein Sec39\tK20475 SEC39; protein transport protein SEC39"
				}
				]
			},
			{
				"name":"Golgi to ER traffic proteins (GET)",
				"children":[
				{
					"name":"2540893 get1; GET complex subunit Get1\tK22384 GET1; tail-anchored protein insertion receptor"
				},
				{
					"name":"2542928 get3; GET complex ATPase subunit Get3\tK01551 arsA; arsenite\/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]"
				},
				{
					"name":"2538767 get4; protein Get4\tK23387 GET4; golgi to ER traffic protein 4"
				}
				]
			},
			{
				"name":"Rab GTPases"
			},
			{
				"name":"Rab associated proteins",
				"children":[
				{
					"name":"2542510 ric1; Rab-specific(Ryh1\/Ypt6) Ric1-Rgp1 guanyl-nucleotide exchange factor subunit Ric1\/Sat4\tK20476 RIC1; RAB6A-GEF complex partner protein 1"
				},
				{
					"name":"2540214 erd2; HDEL receptor\tK10949 KDELR; ER lumen protein retaining receptor"
				},
				{
					"name":"2542423 pep7; FYVE tethering component Pep7\tK12481 RBSN; rabenosyn-5"
				},
				{
					"name":"2540892 gyp1; GTPase-activating protein Gyp1\tK20360 TBC1D22; TBC1 domain family member 2"
				}
				]
			}
			]
		},
		{
			"name":"Others",
			"children":[
			{
				"name":"Oxysterol-binding proteins",
				"children":[
				{
					"name":"2540357 osh2; sterol transfer protein Osh2\tK20456 OSBP; oxysterol-binding protein 1"
				},
				{
					"name":"2541796 osh3; sterol transfer protein Osh3\tK20463 OSBPL3_6_7; oxysterol-binding protein-related protein 3\/6\/7"
				},
				{
					"name":"2539266 osh6; oxysterol binding protein\tK22285 OSBPL8; oxysterol-binding protein-related protein 8"
				},
				{
					"name":"2540206 osh41; oxysterol binding protein\tK20465 OSBPL9_10_11; oxysterol-binding protein-related protein 9\/10\/11"
				},
				{
					"name":"2540947 osh42; oxysterol binding protein\tK20465 OSBPL9_10_11; oxysterol-binding protein-related protein 9\/10\/11"
				},
				{
					"name":"2541093 oss1; oxysterol binding protein\tK20465 OSBPL9_10_11; oxysterol-binding protein-related protein 9\/10\/11"
				}
				]
			},
			{
				"name":"FXYD proteins"
			},
			{
				"name":"YIPF proteins",
				"children":[
				{
					"name":"2541426 yip5; Rab GTPase-binding protein\tK22940 YIPF1_2; protein YIPF1\/2"
				},
				{
					"name":"2539076 SPOM_SPCC61.04C; Rab GTPase-binding protein\tK20363 YIPF5_7; protein YIPF5\/7"
				},
				{
					"name":"2543575 SPOM_SPAC644.13C; Rab GTPase-binding protein\tK22943 YIPF6; protein YIPF6"
				}
				]
			},
			{
				"name":"ER membrane protein complex",
				"children":[
				{
					"name":"2542716 emc1; protein Emc1\tK23562 EMC1; ER membrane protein complex subunit 1"
				},
				{
					"name":"2539872 oca3; TPR repeat-containing protein Oca3\tK23563 EMC2; ER membrane protein complex subunit 2"
				},
				{
					"name":"2539739 emc3; protein Emc3\tK23564 EMC3; ER membrane protein complex subunit 3"
				},
				{
					"name":"2539075 emc4; chaperone EMC4\tK23565 EMC4; ER membrane protein complex subunit 4"
				},
				{
					"name":"2538978 emc6; protein Emc6\tK23567 EMC6; ER membrane protein complex subunit 6"
				}
				]
			},
			{
				"name":"SEC61 complex",
				"children":[
				{
					"name":"2540769 sec6102; translocon subunit Sec61-like protein\tK10956 SEC61A; protein transport protein SEC61 subunit alpha"
				},
				{
					"name":"2541037 sec61; translocon alpha subunit Sec61\tK10956 SEC61A; protein transport protein SEC61 subunit alpha"
				},
				{
					"name":"2540282 sbh1; translocon beta subunit Sbh1\tK09481 SEC61B; protein transport protein SEC61 subunit beta"
				},
				{
					"name":"2543140 sss1; translocon gamma subunit Sss1\tK07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins"
				}
				]
			},
			{
				"name":"TRAP complex"
			},
			{
				"name":"Multi-pass translocon (MPT) complex",
				"children":[
				{
					"name":"2540360 SPOM_SPBC2G5.01; Ca(2+) binding protein\tK24962 CCDC47; PAT complex subunit CCDC47"
				}
				]
			},
			{
				"name":"Post-GPI attachment to proteins factors (PGAP)",
				"children":[
				{
					"name":"2542981 bst1; GPI inositol deacylase\tK05294 PGAP1; GPI inositol-deacylase [EC:3.-.-.-]"
				},
				{
					"name":"2543664 pga3; GPI-phospholipase A2 activity regulator\tK23553 PGAP3; post-GPI attachment to proteins factor 3"
				},
				{
					"name":"2541744 ted1; phosphoprotein phosphatase\tK23362 MPPE1; ethanolamine phosphate phosphodiesterase [EC:3.1.-.-]"
				},
				{
					"name":"2543429 SPOM_SPAC630.12; lipid phosphatase\tK23362 MPPE1; ethanolamine phosphate phosphodiesterase [EC:3.1.-.-]"
				}
				]
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"2539096 sly1; SNARE-binding protein Sly1\tK19998 SCFD1; sec1 family domain-containing protein 1"
				},
				{
					"name":"2539923 tts1; tetra-spanning protein 1\tK20724 TMEM33; transmembrane protein 33"
				},
				{
					"name":"2543427 arv1; Arv1-like family protein Arv1\tK21848 ARV1; lipid intermediate transporter"
				},
				{
					"name":"2541866 SPOM_SPAC23H3.11C; glucosidase\tK21850 KRE6; beta-glucan synthesis-associated protein KRE6"
				},
				{
					"name":"3361544 gpp74; golgi phosphoprotein 3\tK15620 GOLPH3; golgi phosphoprotein 3"
				},
				{
					"name":"2538940 lnp1; protein lunapark\tK23292 LNPK; endoplasmic reticulum junction formation protein lunapark"
				},
				{
					"name":"2539373 ins1; INSIG domain protein\tK26681 INSIG; insulin-induced protein"
				},
				{
					"name":"2541926 sey1; GTP-binding protein Sey1\tK22698 SEY1; protein SEY1 [EC:3.6.5.-]"
				},
				{
					"name":"2540553 nvj2; uncharacterized protein\tK29087 NVJ2; nucleus-vacuole junction protein 2"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Autophagy",
		"children":[
		{
			"name":"Autophagosome formation proteins",
			"children":[
			{
				"name":"ULK complex",
				"children":[
				{
					"name":"2543425 atg13; autophagy-associated protein kinase regulatory subunit Atg13\tK08331 ATG13; autophagy-related protein 13"
				},
				{
					"name":"2542723 atg101; protein Atg101\tK19730 ATG101; autophagy-related protein 101"
				}
				]
			},
			{
				"name":"Atg1 complex",
				"children":[
				{
					"name":"2539461 atg1; autophagy serine\/threonine protein kinase Atg1\tK08269 ULK2; serine\/threonine-protein kinase ULK2 [EC:2.7.11.1]"
				},
				{
					"name":"2543425 atg13; autophagy-associated protein kinase regulatory subunit Atg13\tK08331 ATG13; autophagy-related protein 13"
				},
				{
					"name":"2543011 atg17; autophagy-associated protein kinase activator Atg17\tK08329 ATG17; autophagy-related protein 17"
				}
				]
			},
			{
				"name":"PI3K complex",
				"children":[
				{
					"name":"2543444 pik3; phosphatidylinositol 3-kinase Pik3\tK00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]"
				},
				{
					"name":"2539996 vps15; serine\/threonine protein kinase Vps15\tK08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]"
				},
				{
					"name":"3361548 atg6; beclin family protein\tK08334 BECN; beclin"
				}
				]
			},
			{
				"name":"ATG9 transmembrane protein",
				"children":[
				{
					"name":"2539850 atg9; autophagy-associated protein Atg9\tK17907 ATG9; autophagy-related protein 9"
				}
				]
			},
			{
				"name":"Atg18-Atg2 complex",
				"children":[
				{
					"name":"2542180 SPOM_SPAC589.07C; WD repeat-containing protein Atg1801\tK17908 WIPI1_2; autophagy-related protein 18"
				},
				{
					"name":"3361214 atg2; autophagy-associated protein Atg2\tK17906 ATG2; autophagy-related protein 2"
				}
				]
			},
			{
				"name":"Atg12 conjugation proteins",
				"children":[
				{
					"name":"2542368 atg12; autophagy-associated ubiquitin-like modifier Atg12\tK08336 ATG12; ubiquitin-like protein ATG12"
				},
				{
					"name":"2540790 atg7; E1 Atg8 and Atg12 E1 activating enzyme Atg7\tK08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7"
				},
				{
					"name":"2541913 atg10; autophagy C terminal domain family protein\tK17888 ATG10L; ubiquitin-like-conjugating enzyme ATG10"
				},
				{
					"name":"2540814 atg5; autophagy-associated protein Atg5\tK08339 ATG5; autophagy-related protein 5"
				}
				]
			},
			{
				"name":"Atg8 conjugation proteins",
				"children":[
				{
					"name":"2541386 atg8; autophagy-associated protein Atg8\tK08341 GABARAP; GABA(A) receptor-associated protein"
				},
				{
					"name":"2542182 atg4; Atg8 deconjugator Atg4\tK08342 ATG4; cysteine protease ATG4 [EC:3.4.22.-]"
				},
				{
					"name":"2540790 atg7; E1 Atg8 and Atg12 E1 activating enzyme Atg7\tK08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7"
				},
				{
					"name":"2541025 atg3; autophagy-associated protein Atg3\tK08343 ATG3; ubiquitin-like-conjugating enzyme ATG3"
				}
				]
			}
			]
		},
		{
			"name":"Cytoplasm to vacuolar targeting (CVT) pathway",
			"children":[
			{
				"name":"Selective cargos",
				"children":[
				{
					"name":"2543485 ams1; alpha-mannosidase\tK01191 MAN2C1; alpha-mannosidase [EC:3.2.1.24]"
				},
				{
					"name":"2543605 ape4; aspartyl metalloaminopeptidase Ape4\tK01267 DNPEP; aspartyl aminopeptidase [EC:3.4.11.21]"
				}
				]
			},
			{
				"name":"Cargo receptors"
			},
			{
				"name":"Scaffold protein"
			},
			{
				"name":"Other Cvt associated proteins",
				"children":[
				{
					"name":"2539722 snx41; sorting nexin Snx41\tK21996 SNX41_42; sorting nexin-41\/42"
				},
				{
					"name":"2542427 atg24; autophagy associated protein Atg24\tK17919 SNX4; sorting nexin-4"
				},
				{
					"name":"2541924 atg15; autophagy-associated lipase Atg15\tK17900 ATG15; lipase ATG15 [EC:3.1.1.3]"
				},
				{
					"name":"2541010 vac8; protein Vac8\tK08332 VAC8; vacuolar protein 8"
				}
				]
			}
			]
		},
		{
			"name":"Mitophagy",
			"children":[
			{
				"name":"Cargo receptors"
			},
			{
				"name":"Scaffold proteins"
			},
			{
				"name":"PINK1-Parkin associated proteins",
				"children":[
				{
					"name":"2539859 fzo1; dynamin-like GTPase fzo1\tK06030 MFN2; mitofusin 2 [EC:3.6.5.-]"
				}
				]
			},
			{
				"name":"Other mitophagy associated  proteins",
				"children":[
				{
					"name":"2542634 hxk1; hexokinase 1\tK00844 HK; hexokinase [EC:2.7.1.1]"
				},
				{
					"name":"2543607 hxk2; hexokinase 2\tK00844 HK; hexokinase [EC:2.7.1.1]"
				},
				{
					"name":"2539524 inh1; ATPase inhibitor\tK22255 ATPIF1; ATPase inhibitor, mitochondrial"
				},
				{
					"name":"2540502 tom7; mitochondrial TOM complex subunit Tom7\tK17771 TOM7; mitochondrial import receptor subunit TOM7"
				}
				]
			}
			]
		},
		{
			"name":"Pexophagy",
			"children":[
			{
				"name":"Selective cargos",
				"children":[
				{
					"name":"2541734 pex3; peroxin-3 peroxisome import protein\tK13336 PEX3; peroxin-3"
				}
				]
			},
			{
				"name":"Cargo receptors"
			},
			{
				"name":"Other pexophagy associated proteins",
				"children":[
				{
					"name":"2542437 pex6; peroxin-6\tK13339 PEX6; peroxin-6 [EC:3.6.4.-]"
				}
				]
			}
			]
		},
		{
			"name":"Aggrephagy",
			"children":[
			{
				"name":"Cargo receptors"
			},
			{
				"name":"Scaffold proteins"
			},
			{
				"name":"Other aggrephagy associated proteins",
				"children":[
				{
					"name":"2542744 cdc48; AAA family ATPase involved in ubiquitin-mediated protein degradation Cdc48\tK13525 VCP; transitional endoplasmic reticulum ATPase"
				},
				{
					"name":"2540821 clr3; class 2 histone deacetylase Clr3\tK11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]"
				}
				]
			}
			]
		},
		{
			"name":"Xenophagy",
			"children":[
			{
				"name":"Cargo receptors"
			},
			{
				"name":"Other xenophagy associated proteins"
			}
			]
		},
		{
			"name":"ER-phagy",
			"children":[
			{
				"name":"ER-phagy recepters",
				"children":[
				{
					"name":"2542396 sec62; translocation subcomplex subunit Sec62\tK12275 SEC62; translocation protein SEC62"
				}
				]
			},
			{
				"name":"Other ER-phagy associated proteins",
				"children":[
				{
					"name":"2543041 cnx1; calnexin Cnx1\tK08054 CANX; calnexin"
				},
				{
					"name":"2542688 dap1; cytochrome P450 regulator Dap1\tK17278 PGRMC1_2; membrane-associated progesterone receptor component"
				}
				]
			},
			{
				"name":"ER stress-related proteins",
				"children":[
				{
					"name":"2541815 bip1; ER heat shock protein BiP\tK09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:5.6.1.10]"
				},
				{
					"name":"2543455 tif211; translation initiation factor eIF2 alpha subunit\tK03237 EIF2S1; translation initiation factor 2 subunit 1"
				}
				]
			}
			]
		},
		{
			"name":"Chaperone mediated autophagy (CMA)",
			"children":[
			{
				"name":"Selective cargos",
				"children":[
				{
					"name":"2543020 caa1; aspartate aminotransferase\tK14454 GOT1; aspartate aminotransferase, cytoplasmic [EC:2.6.1.1]"
				},
				{
					"name":"2540547 tdh1; glyceraldehyde-3-phosphate dehydrogenase Tdh1\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
				},
				{
					"name":"2540975 gpd3; glyceraldehyde 3-phosphate dehydrogenase Gpd3\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
				},
				{
					"name":"2542085 gpm1; monomeric 2,3-bisphosphoglycerate (BPG)-dependent phosphoglycerate mutase (PGAM), Gpm1\tK01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]"
				},
				{
					"name":"2543557 pyk1; pyruvate kinase\tK00873 PK; pyruvate kinase [EC:2.7.1.40]"
				},
				{
					"name":"2542667 dsk2; UBA domain protein Dph1\/Dsk2\tK04523 UBQLN; ubiquilin"
				}
				]
			},
			{
				"name":"Cargo receptors"
			},
			{
				"name":"Chaperones",
				"children":[
				{
					"name":"2539225 ssa2; heat shock protein Ssa2\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"2540199 sks2; ribosome-associated molecular chaperone Sks2\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"2542875 ssa1; heat shock protein Ssa1\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"2543539 hsp90; Hsp90 chaperone\tK04079 HSP90A; molecular chaperone HtpG"
				}
				]
			},
			{
				"name":"Co-chaperones"
			},
			{
				"name":"Other CMA associated proteins",
				"children":[
				{
					"name":"2539035 tef101; translation elongation factor EF-1 alpha Ef1a-a\tK03231 EEF1A; elongation factor 1-alpha"
				},
				{
					"name":"2539917 tef103; translation elongation factor EF-1 alpha Ef1a-c\tK03231 EEF1A; elongation factor 1-alpha"
				},
				{
					"name":"2541984 tef102; translation elongation factor EF-1 alpha Ef1a-b\tK03231 EEF1A; elongation factor 1-alpha"
				},
				{
					"name":"2542465 cpy1; vacuolar carboxypeptidase Y\tK13289 CTSA; cathepsin A (carboxypeptidase C) [EC:3.4.16.5]"
				}
				]
			}
			]
		},
		{
			"name":"Other autophagy associated proteins",
			"children":[
			{
				"name":"RNautophagy\/DNautophagy"
			},
			{
				"name":"Micronucleophagy",
				"children":[
				{
					"name":"2541010 vac8; protein Vac8\tK08332 VAC8; vacuolar protein 8"
				}
				]
			},
			{
				"name":"Midbophagy"
			},
			{
				"name":"Glycophagy"
			},
			{
				"name":"TRIM-directed selective autophagy"
			},
			{
				"name":"ER-mitochondria tethering complex",
				"children":[
				{
					"name":"2539859 fzo1; dynamin-like GTPase fzo1\tK06030 MFN2; mitofusin 2 [EC:3.6.5.-]"
				}
				]
			},
			{
				"name":"mTORC1 complex",
				"children":[
				{
					"name":"2540473 tor1; TORC2 serine\/threonine protein kinase Tor1\tK07203 MTOR; serine\/threonine-protein kinase mTOR [EC:2.7.11.1]"
				},
				{
					"name":"2540720 tor2; TORC1 serine\/threonine protein kinase Tor2\tK07203 MTOR; serine\/threonine-protein kinase mTOR [EC:2.7.11.1]"
				},
				{
					"name":"2540645 wat1; TORC1\/2 complex WD repeat protein Wat1\/Lst8\tK08266 MLST8; target of rapamycin complex subunit LST8"
				},
				{
					"name":"2542404 mip1; WD repeat-containing protein\tK07204 RAPTOR; regulatory associated protein of mTOR"
				}
				]
			},
			{
				"name":"mTORC2 complex",
				"children":[
				{
					"name":"2540473 tor1; TORC2 serine\/threonine protein kinase Tor1\tK07203 MTOR; serine\/threonine-protein kinase mTOR [EC:2.7.11.1]"
				},
				{
					"name":"2540720 tor2; TORC1 serine\/threonine protein kinase Tor2\tK07203 MTOR; serine\/threonine-protein kinase mTOR [EC:2.7.11.1]"
				},
				{
					"name":"2540645 wat1; TORC1\/2 complex WD repeat protein Wat1\/Lst8\tK08266 MLST8; target of rapamycin complex subunit LST8"
				},
				{
					"name":"2542972 sin1; MAP kinase-interacting protein Sin1\tK20410 MAPKAP1; target of rapamycin complex 2 subunit MAPKAP1\/AVO1"
				},
				{
					"name":"2539845 ste20; target of rapamycin complex 2 subunit ste20\tK08267 RICTOR; rapamycin-insensitive companion of mTOR"
				},
				{
					"name":"2538963 bit61; Protor homolog, Bit61\tK25577 BIT61_2; target of rapamycin complex 2 subunit BIT61\/BIT2"
				}
				]
			},
			{
				"name":"SEACIT\/GATOR1 complex",
				"children":[
				{
					"name":"2540559 iml1; GATOR1-SEACIT GTPase activating complex subunit Iml1\tK20404 DEPDC5; SEA\/GATOR complex protein SEA1\/DEPDC5"
				},
				{
					"name":"2541840 npr2; Npr2\/3 complex subunit Npr2\tK20405 NPRL2; nitrogen permease regulator 2"
				},
				{
					"name":"2541073 npr3; Npr2\/3 complex subunit Npr3\tK20406 NPRL3; nitrogen permease regulator 3"
				}
				]
			},
			{
				"name":"SEACAT\/GATOR2 complex",
				"children":[
				{
					"name":"2543518 sea2; SEACAT complex subunit Sea2\tK20408 WDR24; SEA\/GATOR complex protein SEA2\/WDR24"
				},
				{
					"name":"2541877 sea3; SEA complex subunit Sea3\tK20409 WDR59; SEA\/GATOR complex protein SEA3\/WDR59"
				},
				{
					"name":"3361381 sea4; GATOR2-SEACAT complex ubiquitin-protein ligase E3 subunit Sea4\tK20407 MIOS; SEA\/GATOR complex protein SEA4\/MIOS"
				},
				{
					"name":"2541682 seh1; GATOR2-SEACAT complex WD repeat subunit Seh1\tK14299 SEH1; nucleoporin SEH1"
				},
				{
					"name":"2540716 sec13; GATOR2-SEACAT complex\/COPII-coated vesicle component\/nuclear pore outer ring WD repeat protein Sec13\tK14004 SEC13; protein transport protein SEC13"
				}
				]
			},
			{
				"name":"KICSTOR complex"
			},
			{
				"name":"Rab GTPases",
				"children":[
				{
					"name":"2539784 ypt1; GTPase Ypt1\tK07874 RAB1A; Ras-related protein Rab-1A"
				},
				{
					"name":"2543280 ypt2; GTPase Ypt2\tK07901 RAB8A; Ras-related protein Rab-8A"
				}
				]
			},
			{
				"name":"Rab associated proteins"
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"2540072 ppa2; serine\/threonine protein phosphatase PP2A catalytic subunit Ppa2\tK04382 PPP2C; serine\/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]"
				},
				{
					"name":"2542052 ppa1; serine\/threonine protein phosphatase PP2A catalytic subunit Ppa1\tK04382 PPP2C; serine\/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]"
				},
				{
					"name":"2539161 tap42; TAP42-like family protein\tK17606 IGBP1; immunoglobulin-binding protein 1"
				},
				{
					"name":"2540836 vps38; phophatidylinositol 3-kinase complex subunit Vps38\tK21249 UVRAG; UV radiation resistance-associated gene protein"
				},
				{
					"name":"2541826 atg22; vacuolar amino acid transmembrane transporter Atg22\tK06902 UMF1; MFS transporter, UMF1 family"
				},
				{
					"name":"2543612 avt3; vacuolar amino acid transmembrane transporter Avt3\tK14209 SLC36A; solute carrier family 36 (proton-coupled amino acid transporter)"
				},
				{
					"name":"9407312 vma21; vacuolar H+-ATPase assembly protein Vma21\tK23952 VMA21; vacuolar ATPase assembly integral membrane protein VMA21"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Others",
		"children":[
		{
			"name":"NADPH oxidases (Nox) and associated proteins",
			"children":[
			{
				"name":"NADPH oxidases"
			},
			{
				"name":"Nox associated proteins"
			}
			]
		},
		{
			"name":"Actin-binding proteins",
			"children":[
			{
				"name":"Myosins",
				"children":[
				{
					"name":"2539659 myo1; myosin I myo1\tK10356 MYO1; myosin I"
				},
				{
					"name":"2538846 myo52; myosin type V\tK10357 MYO5; myosin V"
				},
				{
					"name":"2540560 myo51; myosin type V\tK10357 MYO5; myosin V"
				}
				]
			},
			{
				"name":"Arp2\/3 complex",
				"children":[
				{
					"name":"2540002 arc1; ARP2\/3 actin-organizing complex WD repeat subunit Sop2\tK05757 ARPC1A_B; actin related protein 2\/3 complex, subunit 1A\/1B"
				},
				{
					"name":"2542287 arc2; ARP2\/3 actin-organizing complex subunit Arc34\tK05758 ARPC2; actin related protein 2\/3 complex, subunit 2"
				},
				{
					"name":"2540144 arc3; ARP2\/3 actin-organizing complex subunit Arc21\tK05756 ARPC3; actin related protein 2\/3 complex, subunit 3"
				},
				{
					"name":"2541767 arc4; ARP2\/3 actin-organizing complex subunit Arc4\tK05755 ARPC4; actin related protein 2\/3 complex, subunit 4"
				},
				{
					"name":"2542275 arc5; ARP2\/3 actin-organizing complex subunit Arc5\tK05754 ARPC5; actin related protein 2\/3 complex, subunit 5"
				},
				{
					"name":"5802965 arp2; ARP2\/3 actin-organizing complex actin-related protein subunit Arp2\tK17260 ACTR2; actin-related protein 2"
				},
				{
					"name":"2543233 arp3; ARP2\/3 actin-organizing complex actin-related protein subunit Arp3\tK18584 ACTR3; actin-related protein 3"
				}
				]
			},
			{
				"name":"Nucleation-promoting factors (NPFs)",
				"children":[
				{
					"name":"2543589 wsp1; actin assembly factor\tK23612 WASL; neural Wiskott-Aldrich syndrome protein"
				},
				{
					"name":"2542979 abp1; cofilin\/tropomyosin family protein abp1\tK20520 DBNL; drebrin-like protein"
				},
				{
					"name":"5802955 pan1; actin cortical patch component protein PanI\tK20047 PAN1; actin cytoskeleton-regulatory complex protein PAN1"
				},
				{
					"name":"2540633 hob1; BAR adaptor protein Hob1\tK12562 AMPH; amphiphysin"
				},
				{
					"name":"2542338 shd1; Sla1 family protein Shd1\tK20046 SLA1; actin cytoskeleton-regulatory complex protein SLA1"
				},
				{
					"name":"2542019 bbc1; SH3 domain-containing protein\tK20521 BBC1; myosin tail region-interacting protein MTI1"
				},
				{
					"name":"2539945 lsb1; SH3 domain-containing protein\tK20522 LSB1_2; LAS seventeen-binding protein 1\/2"
				},
				{
					"name":"2543305 lsb4; actin cortical patch component Lsb4\tK20523 SH3YL1; SH3 domain-containing YSC84-like protein 1"
				},
				{
					"name":"2540327 lsb5; protein lsb5\tK20524 LSB5; LAS seventeen-binding protein 5"
				},
				{
					"name":"3361531 lsb6; 1-phosphatidylinositol 4-kinase Lsb6\tK13711 PI4K2; phosphatidylinositol 4-kinase type 2 [EC:2.7.1.67]"
				}
				]
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"2543526 cdc3; profilin\tK05759 PFN; profilin"
				},
				{
					"name":"2541738 adf1; cofilin\tK05765 CFL; cofilin"
				},
				{
					"name":"2538829 cap1; adenylyl cyclase-associated protein Cap1\tK17261 CAP1_2; adenylyl cyclase-associated protein"
				},
				{
					"name":"2543446 stg1; SM22\/transgelin-like actin-modulating protein Stg1\tK20526 TAGLN; transgelin"
				}
				]
			}
			]
		},
		{
			"name":"Mucins",
			"children":[
			{
				"name":"Membrane bound mucins"
			},
			{
				"name":"Secretory mucins"
			}
			]
		},
		{
			"name":"MARVEL domain-containing proteins"
		},
		{
			"name":"Specific organelles associated proteins",
			"children":[
			{
				"name":"Melanosome"
			},
			{
				"name":"Auto phagosome"
			},
			{
				"name":"Lipid droplets",
				"children":[
				{
					"name":"2540872 fit1; CoA pyrophosphatase (FIT) family lipid storage protein\tK28100 FITM2; fat storage-inducing transmembrane protein 2 [EC:3.6.1.-]"
				}
				]
			},
			{
				"name":"Mitochondrion"
			}
			]
		},
		{
			"name":"Rho GTPase associated proteins",
			"children":[
			{
				"name":"Rho GTPase-activating proteins",
				"children":[
				{
					"name":"2540635 rga7; Rho-type GTPase-activating protein Rga7\tK20643 RGD1; Rho GTPase-activating protein RGD1"
				},
				{
					"name":"2542682 rga2; putative Rho-type GTPase-activating protein Rga2\tK08773 RALBP1; RalA-binding protein 1"
				}
				]
			},
			{
				"name":"Rho guanine nucleotide exchange factors (GEFs)"
			}
			]
		}
		]
	}
	]
}