{
	"name":"ssc03400",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair",
				"children":[
				{
					"name":"100155050 MGMT; methylated-DNA--protein-cysteine methyltransferase isoform X3\tK00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]"
				},
				{
					"name":"100520333 ALKBH2; DNA oxidative demethylase ALKBH2\tK10859 ALKBH2; DNA oxidative demethylase [EC:1.14.11.33]"
				},
				{
					"name":"100624169 ALKBH3; alpha-ketoglutarate-dependent dioxygenase alkB homolog 3\tK10860 ALKBH3; mRNA N1-methyladenine demethylase [EC:1.14.11.54]"
				},
				{
					"name":"100625273 ASCC3; activating signal cointegrator 1 complex subunit 3 isoform X1\tK18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4]"
				}
				]
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"100519979 UNG; uracil-DNA glycosylase\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"100517790 CCNO; cyclin-O\tK10861 UDG2; uracil-DNA glycosylase 2 [EC:3.2.2.-]"
					},
					{
						"name":"100155184 TDG; G\/T mismatch-specific thymine DNA glycosylase\tK20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]"
					},
					{
						"name":"100525334 MPG; DNA-3-methyladenine glycosylase\tK03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]"
					},
					{
						"name":"100153912 SMUG1; single-strand selective monofunctional uracil DNA glycosylase isoform X2\tK10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]"
					},
					{
						"name":"100513867 MUTYH; adenine DNA glycosylase isoform X1\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
					},
					{
						"name":"110256288 MBD4; methyl-CpG-binding domain protein 4 isoform X1\tK10801 MBD4; methyl-CpG-binding domain protein 4 [EC:3.2.2.-]"
					},
					{
						"name":"100155036 OGG1; LOW QUALITY PROTEIN: N-glycosylase\/DNA lyase\tK03660 OGG1; N-glycosylase\/DNA lyase [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"100155341 NEIL1; endonuclease 8-like 1 isoform X1\tK10567 NEIL1; endonuclease VIII-like 1 [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"100624483 NEIL2; endonuclease 8-like 2\tK10568 NEIL2; endonuclease VIII-like 2 [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"100156631 NEIL3; endonuclease 8-like 3 isoform X1\tK10569 NEIL3; endonuclease VIII-like 3 [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"100516255 NTHL1; endonuclease III-like protein 1 isoform X7\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases",
					"children":[
					{
						"name":"100154728 APEX1; DNA-(apurinic or apyrimidinic site) lyase\tK10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]"
					},
					{
						"name":"100519003 APEX2; DNA-(apurinic or apyrimidinic site) lyase 2\tK10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]"
					}
					]
				},
				{
					"name":"Long Patch-BER factors",
					"children":[
					{
						"name":"DNA polymerase delta complex",
						"children":[
						{
							"name":"100525752 POLD1; DNA polymerase delta catalytic subunit isoform X2\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
						},
						{
							"name":"100514809 POLD2; DNA polymerase delta subunit 2\tK02328 POLD2; DNA polymerase delta subunit 2"
						},
						{
							"name":"100626052 POLD3; DNA polymerase delta subunit 3\tK03504 POLD3; DNA polymerase delta subunit 3"
						},
						{
							"name":"100736957 POLD4; DNA polymerase delta subunit 4\tK03505 POLD4; DNA polymerase delta subunit 4"
						}
						]
					},
					{
						"name":"DNA polymerase epsilon complex",
						"children":[
						{
							"name":"100620959 POLE; DNA polymerase epsilon catalytic subunit A\tK02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]"
						},
						{
							"name":"100521651 POLE2; DNA polymerase epsilon subunit 2 isoform X1\tK02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]"
						},
						{
							"name":"100517450 POLE3; DNA polymerase epsilon subunit 3\tK02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]"
						},
						{
							"name":"100517646 POLE4; DNA polymerase epsilon subunit 4 isoform X1\tK03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]"
						}
						]
					},
					{
						"name":"692192 PCNA; proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"100517749 FEN1; flap endonuclease 1\tK04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]"
					},
					{
						"name":"100520434 LIG1; DNA ligase 1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					}
					]
				},
				{
					"name":"Short Patch-BER factors",
					"children":[
					{
						"name":"100526021 POLB; LOW QUALITY PROTEIN: DNA polymerase beta\tK02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]"
					},
					{
						"name":"100519604 XRCC1; DNA repair protein XRCC1 isoform X1\tK10803 XRCC1; DNA-repair protein XRCC1"
					},
					{
						"name":"100626381 LIG3; DNA ligase 3\tK10776 LIG3; DNA ligase 3 [EC:6.5.1.1]"
					}
					]
				},
				{
					"name":"Other BER factors",
					"children":[
					{
						"name":"100153247 TDP1; tyrosyl-DNA phosphodiesterase 1 isoform X3\tK10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]"
					},
					{
						"name":"387596 APTX; aprataxin\tK10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]"
					},
					{
						"name":"100516073 APLF; aprataxin and PNK-like factor isoform X1\tK13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-]"
					},
					{
						"name":"100522442 PNKP; bifunctional polynucleotide phosphatase\/kinase isoform X1\tK08073 PNKP; bifunctional polynucleotide phosphatase\/kinase [EC:3.1.3.32 2.7.1.78]"
					},
					{
						"name":"445521 HMGB1; high mobility group protein B1\tK10802 HMGB1; high mobility group protein B1"
					},
					{
						"name":"100153781 POLL; DNA polymerase lambda isoform X1\tK03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]"
					},
					{
						"name":"100621034 PARP1; LOW QUALITY PROTEIN: poly [ADP-ribose] polymerase 1\tK24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]"
					},
					{
						"name":"100518917 PARP2; poly [ADP-ribose] polymerase 2\tK28005 PARP2; poly [ADP-ribose] polymerase 2 [EC:2.4.2.30]"
					},
					{
						"name":"100620838 PARP3; poly [ADP-ribose] polymerase 3 isoform X1\tK10798 PARP3_4; protein mono-ADP-ribosyltransferase 3\/4 [EC:2.4.2.-]"
					},
					{
						"name":"100738726 PARP4; poly [ADP-ribose] polymerase 4\tK10798 PARP3_4; protein mono-ADP-ribosyltransferase 3\/4 [EC:2.4.2.-]"
					}
					]
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors",
					"children":[
					{
						"name":"XPC-HR23B-CETN2 complex",
						"children":[
						{
							"name":"100514251 XPC; DNA repair protein complementing XP-C cells isoform X8\tK10838 XPC; xeroderma pigmentosum group C-complementing protein"
						},
						{
							"name":"100153668 RAD23B; UV excision repair protein RAD23 homolog B\tK10839 RAD23; UV excision repair protein RAD23"
						},
						{
							"name":"100524483 RAD23A; UV excision repair protein RAD23 homolog A isoform X1\tK10839 RAD23; UV excision repair protein RAD23"
						},
						{
							"name":"606742 CETN2; centrin-2\tK10840 CETN2; centrin-2"
						}
						]
					},
					{
						"name":"Cul4-DDB2 complex",
						"children":[
						{
							"name":"110260638 RBX1; E3 ubiquitin-protein ligase RBX1 isoform X1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
						},
						{
							"name":"100513454 CUL4B; cullin-4B isoform X3\tK10609 CUL4; cullin 4"
						},
						{
							"name":"100517912 CUL4A; cullin-4A\tK10609 CUL4; cullin 4"
						},
						{
							"name":"100522239 DDB1; LOW QUALITY PROTEIN: DNA damage-binding protein 1\tK10610 DDB1; DNA damage-binding protein 1"
						},
						{
							"name":"100513197 DDB2; DNA damage-binding protein 2 isoform X2\tK10140 DDB2; DNA damage-binding protein 2"
						}
						]
					},
					{
						"name":"NER4 complex"
					}
					]
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase II complex",
						"children":[
						{
							"name":"100737040 POLR2A; LOW QUALITY PROTEIN: DNA-directed RNA polymerase II subunit RPB1\tK03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]"
						},
						{
							"name":"397001 POLR2B; DNA-directed RNA polymerase II subunit RPB2\tK03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]"
						},
						{
							"name":"100620737 POLR2C; DNA-directed RNA polymerase II subunit RPB3\tK03011 RPB3; DNA-directed RNA polymerase II subunit RPB3"
						},
						{
							"name":"100737579 POLR2D; DNA-directed RNA polymerase II subunit RPB4 isoform X1\tK03012 RPB4; DNA-directed RNA polymerase II subunit RPB4"
						},
						{
							"name":"100623333 POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1\tK03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1"
						},
						{
							"name":"100737214 POLR2F; DNA-directed RNA polymerases I, II, and III subunit RPABC2\tK03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2"
						},
						{
							"name":"100620235 POLR2G; DNA-directed RNA polymerase II subunit RPB7\tK03015 RPB7; DNA-directed RNA polymerase II subunit RPB7"
						},
						{
							"name":"100628241 POLR2H; DNA-directed RNA polymerases I, II, and III subunit RPABC3\tK03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3"
						},
						{
							"name":"414403 POLR2I; DNA-directed RNA polymerase II subunit RPB9 isoform 1\tK03017 RPB9; DNA-directed RNA polymerase II subunit RPB9"
						},
						{
							"name":"100156985 DNA-directed RNA polymerases I, II, and III subunit RPABC5-like\tK03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5"
						},
						{
							"name":"100511241 POLR2L; DNA-directed RNA polymerases I, II, and III subunit RPABC5\tK03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5"
						},
						{
							"name":"100521614 POLR2J; DNA-directed RNA polymerase II subunit RPB11-a\tK03008 RPB11; DNA-directed RNA polymerase II subunit RPB11"
						},
						{
							"name":"100524560 POLR2K; DNA-directed RNA polymerases I, II, and III subunit RPABC4\tK03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4"
						}
						]
					},
					{
						"name":"Cul4-CSA complex",
						"children":[
						{
							"name":"110260638 RBX1; E3 ubiquitin-protein ligase RBX1 isoform X1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
						},
						{
							"name":"100513454 CUL4B; cullin-4B isoform X3\tK10609 CUL4; cullin 4"
						},
						{
							"name":"100517912 CUL4A; cullin-4A\tK10609 CUL4; cullin 4"
						},
						{
							"name":"100522239 DDB1; LOW QUALITY PROTEIN: DNA damage-binding protein 1\tK10610 DDB1; DNA damage-binding protein 1"
						},
						{
							"name":"100524405 ERCC8; DNA excision repair protein ERCC-8 isoform X1\tK10570 ERCC8; DNA excision repair protein ERCC-8"
						}
						]
					},
					{
						"name":"Other TCR factor",
						"children":[
						{
							"name":"106504057 ERCC6; LOW QUALITY PROTEIN: DNA excision repair protein ERCC-6\tK10841 ERCC6; DNA excision repair protein ERCC-6"
						},
						{
							"name":"110262039 UVSSA; UV-stimulated scaffold protein A isoform X1\tK23720 UVSSA; UV-stimulated scaffold protein A"
						},
						{
							"name":"100519241 ELOF1; transcription elongation factor 1 homolog\tK25829 ELOF1; transcription elongation factor 1"
						}
						]
					}
					]
				},
				{
					"name":"TFIIH complex",
					"children":[
					{
						"name":"100517918 ERCC3; TFIIH basal transcription factor complex helicase XPB subunit\tK10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]"
					},
					{
						"name":"100049685 ERCC2; TFIIH basal transcription factor complex helicase XPD subunit isoform X1\tK10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]"
					},
					{
						"name":"100525504 GTF2H1; general transcription factor IIH subunit 1\tK03141 TFIIH1; transcription initiation factor TFIIH subunit 1"
					},
					{
						"name":"100625544 GTF2H2; general transcription factor IIH subunit 2\tK03142 TFIIH2; transcription initiation factor TFIIH subunit 2"
					},
					{
						"name":"100152121 GTF2H3; general transcription factor IIH subunit 3 isoform X1\tK03143 TFIIH3; transcription initiation factor TFIIH subunit 3"
					},
					{
						"name":"100144458 GTF2H4; general transcription factor IIH subunit 4\tK03144 TFIIH4; transcription initiation factor TFIIH subunit 4"
					},
					{
						"name":"100739493 GTF2H5; general transcription factor IIH subunit 5\tK10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit"
					},
					{
						"name":"100310797 CDK7; cyclin-dependent kinase 7\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]"
					},
					{
						"name":"100310796 CCNH; cyclin-H\tK06634 CCNH; cyclin H"
					},
					{
						"name":"100310799 MNAT1; CDK-activating kinase assembly factor MAT1\tK10842 MNAT1; CDK-activating kinase assembly factor MAT1"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"100525428 RPA1; replication protein A 70 kDa DNA-binding subunit\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"100514295 RPA2; replication protein A 32 kDa subunit\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"100624116 RPA3; replication protein A 14 kDa subunit\tK10740 RPA3; replication factor A3"
					}
					]
				},
				{
					"name":"Other NER factors",
					"children":[
					{
						"name":"100522779 XPA; DNA repair protein complementing XP-A cells\tK10847 XPA; DNA-repair protein complementing XP-A cells"
					},
					{
						"name":"100286808 ERCC1; DNA excision repair protein ERCC-1\tK10849 ERCC1; DNA excision repair protein ERCC-1"
					},
					{
						"name":"100516427 ERCC4; LOW QUALITY PROTEIN: DNA repair endonuclease XPF\tK10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]"
					},
					{
						"name":"102163752 ERCC5; DNA repair protein complementing XP-G cells\tK10846 ERCC5; DNA excision repair protein ERCC-5"
					},
					{
						"name":"100520434 LIG1; DNA ligase 1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					},
					{
						"name":"100157608 MMS19; MMS19 nucleotide excision repair protein homolog\tK15075 MET18; DNA repair\/transcription protein MET18\/MMS19"
					},
					{
						"name":"110256859 CCDC117; coiled-coil domain-containing protein 117 isoform X1\tK27967 CCDC117; coiled-coil domain-containing protein 117"
					},
					{
						"name":"100738991 CIAO1; probable cytosolic iron-sulfur protein assembly protein CIAO1 isoform X2\tK24730 CIAO1; cytosolic iron-sulfur protein assembly protein CIAO1"
					},
					{
						"name":"100156836 FAM96A; MIP18 family protein FAM96A isoform X1\tK26403 CIAO2; cytosolic iron-sulfur assembly component 2"
					},
					{
						"name":"100627721 FAM96B; mitotic spindle-associated MMXD complex subunit MIP18\tK26403 CIAO2; cytosolic iron-sulfur assembly component 2"
					},
					{
						"name":"100511787 CUL3; cullin-3 isoform X1\tK03869 CUL3; cullin 3"
					},
					{
						"name":"100525708 CUL5; cullin-5 isoform X1\tK10612 CUL5; cullin 5"
					},
					{
						"name":"100153381 ELOC; elongin-C\tK03872 ELOC; elongin-C"
					},
					{
						"name":"100519651 ELOB; elongin-B\tK03873 ELOB; elongin-B"
					},
					{
						"name":"100620801 ELOA; elongin-A\tK15076 ELOA; elongin-A"
					},
					{
						"name":"100517710 UBAP2L; ubiquitin-associated protein 2-like isoform X11\tK26545 UBAP2; ubiquitin-associated protein 2"
					},
					{
						"name":"100525603 UBAP2; ubiquitin-associated protein 2 isoform X4\tK26545 UBAP2; ubiquitin-associated protein 2"
					}
					]
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors",
					"children":[
					{
						"name":"100337661 MSH2; DNA mismatch repair protein Msh2\tK08735 MSH2; DNA mismatch repair protein MSH2"
					},
					{
						"name":"100512158 MSH3; LOW QUALITY PROTEIN: DNA mismatch repair protein Msh3\tK08736 MSH3; DNA mismatch repair protein MSH3"
					},
					{
						"name":"100624450 MSH6; DNA mismatch repair protein Msh6 isoform X2\tK08737 MSH6; DNA mismatch repair protein MSH6"
					}
					]
				},
				{
					"name":"MutL homologs",
					"children":[
					{
						"name":"100513383 PMS1; PMS1 protein homolog 1 isoform X1\tK10864 PMS1; DNA mismatch repair protein PMS1"
					},
					{
						"name":"100337665 MLH1; DNA mismatch repair protein Mlh1\tK08734 MLH1; DNA mismatch repair protein MLH1"
					},
					{
						"name":"100514342 PMS2; mismatch repair endonuclease PMS2 isoform X1\tK10858 PMS2; DNA mismatch repair protein PMS2"
					}
					]
				},
				{
					"name":"DNA polymerase delta complex",
					"children":[
					{
						"name":"100525752 POLD1; DNA polymerase delta catalytic subunit isoform X2\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
					},
					{
						"name":"100514809 POLD2; DNA polymerase delta subunit 2\tK02328 POLD2; DNA polymerase delta subunit 2"
					},
					{
						"name":"100626052 POLD3; DNA polymerase delta subunit 3\tK03504 POLD3; DNA polymerase delta subunit 3"
					},
					{
						"name":"100736957 POLD4; DNA polymerase delta subunit 4\tK03505 POLD4; DNA polymerase delta subunit 4"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"100525428 RPA1; replication protein A 70 kDa DNA-binding subunit\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"100514295 RPA2; replication protein A 32 kDa subunit\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"100624116 RPA3; replication protein A 14 kDa subunit\tK10740 RPA3; replication factor A3"
					}
					]
				},
				{
					"name":"RFC (replication factor C)",
					"children":[
					{
						"name":"100511271 RFC1; replication factor C subunit 1 isoform X2\tK10754 RFC1; replication factor C subunit 1"
					},
					{
						"name":"100620242 RFC2; replication factor C subunit 2 isoform X1\tK10755 RFC2_4; replication factor C subunit 2\/4"
					},
					{
						"name":"106504063 RFC4; replication factor C subunit 4 isoform X1\tK10755 RFC2_4; replication factor C subunit 2\/4"
					},
					{
						"name":"100153965 RFC5; replication factor C subunit 5\tK10756 RFC3_5; replication factor C subunit 3\/5"
					},
					{
						"name":"100156440 RFC3; replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
					}
					]
				},
				{
					"name":"Other MMR factors",
					"children":[
					{
						"name":"692192 PCNA; proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"100512301 EXO1; exonuclease 1 isoform X1\tK10746 EXO1; exonuclease 1 [EC:3.1.-.-]"
					},
					{
						"name":"445521 HMGB1; high mobility group protein B1\tK10802 HMGB1; high mobility group protein B1"
					},
					{
						"name":"100520434 LIG1; DNA ligase 1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					},
					{
						"name":"100519285 WDR76; WD repeat-containing protein 76 isoform X2\tK24755 WDR76; WD repeat-containing protein 76"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"MRN(MRX) complex",
					"children":[
					{
						"name":"100516687 MRE11; LOW QUALITY PROTEIN: double-strand break repair protein MRE11\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"100522666 RAD50; DNA repair protein RAD50\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					},
					{
						"name":"100153233 NBN; nibrin isoform X1\tK10867 NBN; nibrin"
					}
					]
				},
				{
					"name":"BRCA1-core complex",
					"children":[
					{
						"name":"100049662 BRCA1; breast cancer type 1 susceptibility protein isoform X15\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"100511662 BARD1; BRCA1-associated RING domain protein 1\tK10683 BARD1; BRCA1-associated RING domain protein 1"
					}
					]
				},
				{
					"name":"BRCA1-A complex",
					"children":[
					{
						"name":"100049662 BRCA1; breast cancer type 1 susceptibility protein isoform X15\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"100524450 ABRAXAS1; BRCA1-A complex subunit Abraxas isoform X1\tK20774 FAM175A; BRCA1-A complex subunit Abraxas"
					},
					{
						"name":"100037949 UIMC1; BRCA1-A complex subunit RAP80\tK20775 UIMC1; BRCA1-A complex subunit RAP80"
					},
					{
						"name":"100620886 BABAM1; BRISC and BRCA1-A complex member 1\tK20776 BABAM; BRISC and BRCA1-A complex member 1"
					},
					{
						"name":"100623966 BABAM2; BRCA1-A complex subunit BRE isoform X1\tK12173 BRE; BRCA1-A complex subunit BRE"
					},
					{
						"name":"100516948 BRCC3; lys-63-specific deubiquitinase BRCC36\tK11864 BRCC3; BRCA1\/BRCA2-containing complex subunit 3 [EC:3.4.19.-]"
					}
					]
				},
				{
					"name":"BRCA1-B complex",
					"children":[
					{
						"name":"100049662 BRCA1; breast cancer type 1 susceptibility protein isoform X15\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"100525359 BRIP1; LOW QUALITY PROTEIN: Fanconi anemia group J protein\tK15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]"
					},
					{
						"name":"100626645 TOPBP1; DNA topoisomerase 2-binding protein 1 isoform X5\tK10728 TOPBP1; topoisomerase (DNA) II binding protein 1"
					}
					]
				},
				{
					"name":"BRCA1-C complex",
					"children":[
					{
						"name":"100049662 BRCA1; breast cancer type 1 susceptibility protein isoform X15\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"100621518 RBBP8; DNA endonuclease RBBP8 isoform X2\tK20773 RBBP8; DNA endonuclease RBBP8 [EC:3.1.-.-]"
					},
					{
						"name":"100516687 MRE11; LOW QUALITY PROTEIN: double-strand break repair protein MRE11\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"100522666 RAD50; DNA repair protein RAD50\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					},
					{
						"name":"100153233 NBN; nibrin isoform X1\tK10867 NBN; nibrin"
					}
					]
				},
				{
					"name":"BRCA complex",
					"children":[
					{
						"name":"100049662 BRCA1; breast cancer type 1 susceptibility protein isoform X15\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"100624979 BRCA2; LOW QUALITY PROTEIN: breast cancer type 2 susceptibility protein\tK08775 BRCA2; breast cancer 2 susceptibility protein"
					},
					{
						"name":"100523630 PALB2; partner and localizer of BRCA2 isoform X3\tK10897 PALB2; partner and localizer of BRCA2"
					},
					{
						"name":"100141309 RAD51; DNA repair protein RAD51 homolog 1\tK04482 RAD51; DNA repair protein RAD51"
					}
					]
				},
				{
					"name":"RecA family proteins",
					"children":[
					{
						"name":"100141309 RAD51; DNA repair protein RAD51 homolog 1\tK04482 RAD51; DNA repair protein RAD51"
					},
					{
						"name":"100519785 RAD51B; DNA repair protein RAD51 homolog 2 isoform X3\tK10869 RAD51L1; RAD51-like protein 1"
					},
					{
						"name":"100518577 RAD51C; DNA repair protein RAD51 homolog 3 isoform X5\tK10870 RAD51L2; RAD51-like protein 2"
					},
					{
						"name":"100626849 RAD51D; DNA repair protein RAD51 homolog 4 isoform X1\tK10871 RAD51L3; RAD51-like protein 3"
					},
					{
						"name":"100514260 XRCC2; DNA repair protein XRCC2 isoform X1\tK10879 XRCC2; DNA-repair protein XRCC2"
					},
					{
						"name":"100522195 XRCC3; DNA repair protein XRCC3 isoform X2\tK10880 XRCC3; DNA-repair protein XRCC3"
					}
					]
				},
				{
					"name":"Rad52 family proteins",
					"children":[
					{
						"name":"100141308 RAD52; DNA repair protein RAD52 homolog\tK10873 RAD52; DNA repair and recombination protein RAD52"
					},
					{
						"name":"100625662 LOW QUALITY PROTEIN: RAD52 motif-containing protein 1-like\tK10874 RDM1; RAD52 motif-containing protein 1"
					}
					]
				},
				{
					"name":"Rad54 family proteins",
					"children":[
					{
						"name":"100141305 RAD54L; DNA repair and recombination protein RAD54-like\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]"
					},
					{
						"name":"100520639 RAD54L2; helicase ARIP4 isoform X1\tK10876 RAD54L2; RAD54-like protein 2 [EC:5.6.2.-]"
					},
					{
						"name":"100513148 RAD54B; LOW QUALITY PROTEIN: DNA repair and recombination protein RAD54B\tK10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-]"
					}
					]
				},
				{
					"name":"RecQ family DNA helicases",
					"children":[
					{
						"name":"100621847 RECQL; ATP-dependent DNA helicase Q1\tK10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]"
					},
					{
						"name":"100512139 WRN; Werner syndrome ATP-dependent helicase isoform X1\tK10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4]"
					},
					{
						"name":"100141304 BLM; Bloom syndrome protein\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"100524433 RECQL4; ATP-dependent DNA helicase Q4 isoform X1\tK10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]"
					},
					{
						"name":"100626380 RECQL5; ATP-dependent DNA helicase Q5 isoform X1\tK10902 RECQL5; ATP-dependent DNA helicase Q5 [EC:5.6.2.4]"
					}
					]
				},
				{
					"name":"Bloom's syndrome complex (BTR)",
					"children":[
					{
						"name":"100141304 BLM; Bloom syndrome protein\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"100155140 TOP3B; LOW QUALITY PROTEIN: DNA topoisomerase 3-beta-1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"110256129 TOP3A; DNA topoisomerase 3-alpha isoform X1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"100517963 RMI1; recQ-mediated genome instability protein 1\tK10990 RMI1; RecQ-mediated genome instability protein 1"
					},
					{
						"name":"100518832 RMI2; recQ-mediated genome instability protein 2\tK15365 RMI2; RecQ-mediated genome instability protein 2"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"100525428 RPA1; replication protein A 70 kDa DNA-binding subunit\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"100514295 RPA2; replication protein A 32 kDa subunit\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"100624116 RPA3; replication protein A 14 kDa subunit\tK10740 RPA3; replication factor A3"
					}
					]
				},
				{
					"name":"Protein phosphatase 4",
					"children":[
					{
						"name":"110260085 PPP4C; serine\/threonine-protein phosphatase 4 catalytic subunit\tK15423 PPP4C; serine\/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"100151752 PPP4R1L; uncharacterized protein PPP4R1L isoform X1\tK15424 PPP4R1; serine\/threonine-protein phosphatase 4 regulatory subunit 1"
					},
					{
						"name":"100624877 PPP4R1; serine\/threonine-protein phosphatase 4 regulatory subunit 1 isoform X1\tK15424 PPP4R1; serine\/threonine-protein phosphatase 4 regulatory subunit 1"
					},
					{
						"name":"100626659 PPP4R2; serine\/threonine-protein phosphatase 4 regulatory subunit 2 isoform X1\tK15425 PPP4R2; serine\/threonine-protein phosphatase 4 regulatory subunit 2"
					},
					{
						"name":"100157672 PPP4R3A; serine\/threonine-protein phosphatase 4 regulatory subunit 3A isoform X2\tK17491 SMEK; protein phosphatase 4 regulatory subunit 3"
					},
					{
						"name":"100512224 PPP4R3B; serine\/threonine-protein phosphatase 4 regulatory subunit 3B\tK17491 SMEK; protein phosphatase 4 regulatory subunit 3"
					},
					{
						"name":"100737576 PPP4R4; serine\/threonine-protein phosphatase 4 regulatory subunit 4 isoform X1\tK15426 PPP4R4; serine\/threonine-protein phosphatase 4 regulatory subunit 4"
					}
					]
				},
				{
					"name":"AP-5 complex",
					"children":[
					{
						"name":"100511736 AP5B1; AP-5 complex subunit beta-1\tK19022 AP5B1; AP-5 complex subunit beta-1"
					},
					{
						"name":"100153219 AP5M1; AP-5 complex subunit mu-1 isoform X1\tK19023 AP5M1; AP-5 complex subunit mu-1"
					},
					{
						"name":"100524719 AP5S1; AP-5 complex subunit sigma-1 isoform X1\tK19024 AP5S1; AP-5 complex subunit sigma-1"
					},
					{
						"name":"100513142 AP5Z1; AP-5 complex subunit zeta-1\tK19025 AP5Z1; AP-5 complex subunit zeta-1"
					}
					]
				},
				{
					"name":"SMC5-SMC6 complex",
					"children":[
					{
						"name":"100515003 SMC5; structural maintenance of chromosomes protein 5 isoform X1\tK22803 SMC5; structural maintenance of chromosomes protein 5"
					},
					{
						"name":"100517523 SMC6; structural maintenance of chromosomes protein 6\tK22804 SMC6; structural maintenance of chromosomes protein 6"
					},
					{
						"name":"100518964 FAM84A; protein FAM84A\tK22805 FAM84A; protein FAM84A"
					},
					{
						"name":"100626278 NSMCE1; non-structural maintenance of chromosomes element 1 homolog isoform X1\tK22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]"
					},
					{
						"name":"106509960 NSMCE2; E3 SUMO-protein ligase NSE2 isoform X1\tK22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]"
					},
					{
						"name":"100620354 NSMCE3; non-structural maintenance of chromosomes element 3 homolog\tK22823 NSMCE3; non-structural maintenance of chromosomes element 3"
					},
					{
						"name":"100153999 NSMCE4A; non-structural maintenance of chromosomes element 4 homolog A\tK22825 NSMCE4; non-structural maintenance of chromosomes element 4"
					},
					{
						"name":"100514233 EID3; EP300-interacting inhibitor of differentiation 3\tK22826 EID3; EP300-interacting inhibitor of differentiation 3"
					},
					{
						"name":"100522125 SLF1; SMC5-SMC6 complex localization factor protein 1 isoform X1\tK26126 SLF1; SMC5-SMC6 complex localization factor protein 1"
					},
					{
						"name":"110256637 SMC5-SMC6 complex localization factor protein 2 isoform X1\tK26127 SLF2; SMC5-SMC6 complex localization factor protein 2"
					},
					{
						"name":"100513398 SIMC1; SUMO-interacting motif-containing protein 1 isoform X1\tK28408 SIMC1; SUMO-interacting motif-containing protein 1"
					}
					]
				},
				{
					"name":"Other HR factors",
					"children":[
					{
						"name":"100516510 EME1; crossover junction endonuclease EME1\tK10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]"
					},
					{
						"name":"100521548 EME2; LOW QUALITY PROTEIN: probable crossover junction endonuclease EME2\tK10883 EME2; crossover junction endonuclease EME2"
					},
					{
						"name":"100155300 EXD2; exonuclease 3'-5' domain-containing protein 2 isoform X1\tK20777 EXD2; exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1]"
					},
					{
						"name":"100511000 MUS81; crossover junction endonuclease MUS81 isoform X3\tK08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]"
					},
					{
						"name":"100155621 SEM1; 26S proteasome complex subunit SEM1\tK10881 SHFM1; 26 proteasome complex subunit DSS1"
					},
					{
						"name":"100157025 SFR1; swi5-dependent recombination DNA repair protein 1 homolog\tK10992 SFR1; Swi5-dependent recombination DNA repair protein 1"
					},
					{
						"name":"100621669 SLX1A; structure-specific endonuclease subunit SLX1\tK15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]"
					},
					{
						"name":"100515719 SLX4; structure-specific endonuclease subunit SLX4 isoform X1\tK10484 BTBD12; structure-specific endonuclease subunit SLX4 (BTB\/POZ domain-containing protein 12)"
					},
					{
						"name":"100517338 GEN1; flap endonuclease GEN homolog 1\tK15338 GEN1; holliday junction resolvase GEN1\/YEN1 [EC:3.1.-.-]"
					},
					{
						"name":"100522412 SPG11; spatacsin isoform X1\tK19026 SPG11; spatacsin"
					},
					{
						"name":"100155869 ZFYVE26; LOW QUALITY PROTEIN: zinc finger FYVE domain-containing protein 26\tK19027 ZFYVE26; zinc finger FYVE domain-containing protein 26"
					},
					{
						"name":"100157339 RAD51AP1; RAD51-associated protein 1\tK20778 RAD51AP1; RAD51-associated protein 1"
					},
					{
						"name":"100626322 NUCKS1; nuclear ubiquitous casein and cyclin-dependent kinase substrate 1\tK28888 NUCKS1; nuclear ubiquitous casein and cyclin-dependent kinase substrate 1"
					},
					{
						"name":"100154823 MORF4L1; mortality factor 4-like protein 1 isoform X2\tK11339 MORF4L1; mortality factor 4-like protein 1"
					},
					{
						"name":"100154500 deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like\tK22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]"
					},
					{
						"name":"100625562 FIGNL1; fidgetin-like protein 1\tK22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]"
					},
					{
						"name":"106510091 SPIDR; DNA repair-scaffolding protein isoform X1\tK22806 SPIDR; DNA repair-scaffolding protein"
					},
					{
						"name":"100623936 FAM84B; protein FAM84B\tK22810 FAM84B; protein FAM84B"
					},
					{
						"name":"100623177 BRAT1; BRCA1-associated ATM activator 1 isoform X1\tK23112 BRAT1; BRCA1-associated ATM activator 1"
					},
					{
						"name":"100621858 C13H21orf2; protein C21orf2 isoform X1\tK23456 CFAP410; cilla- and flagella-associated protein"
					},
					{
						"name":"100526035 HDGFL2; hepatoma-derived growth factor-related protein 2 isoform X3\tK25065 HDGFL2; hepatoma-derived growth factor-related protein 2"
					},
					{
						"name":"100625779 ZSWIM7; zinc finger SWIM domain-containing protein 7\tK25770 ZSWIM7; zinc finger SWIM domain-containing protein 7"
					},
					{
						"name":"100515253 SWSAP1; ATPase SWSAP1\tK25771 SWSAP1; ATPase SWSAP1"
					},
					{
						"name":"100621182 EMSY; BRCA2-interacting transcriptional repressor EMSY isoform X7\tK25790 EMSY; BRCA2-interacting transcriptional repressor EMSY"
					},
					{
						"name":"100621369 HSF2BP; heat shock factor 2-binding protein isoform X1\tK25791 HSF2BP; heat shock factor 2-binding protein"
					},
					{
						"name":"100513056 MMS22L; protein MMS22-like isoform X1\tK26125 MMS22L; protein MMS22-like"
					},
					{
						"name":"100153638 TONSL; tonsoku-like protein isoform X2\tK09257 NFKBIL2; NF-kappa-B inhibitor-like protein 2"
					},
					{
						"name":"100525295 BOD1L1; biorientation of chromosomes in cell division protein 1-like 1 isoform X2\tK27262 BOD1L1; biorientation of chromosomes in cell division protein 1-like 1"
					},
					{
						"name":"100523000 PARPBP; PCNA-interacting partner isoform X2\tK27412 PARPBP; PCNA-interacting partner"
					},
					{
						"name":"100514980 C12H17orf53; uncharacterized protein C17orf53 homolog isoform X1\tK27803 HROB; homologous recombination OB-fold protein"
					},
					{
						"name":"100154307 MCM8; DNA helicase MCM8\tK10737 MCM8; DNA helicase MCM8 [EC:5.6.2.4]"
					},
					{
						"name":"100519693 MCM9; LOW QUALITY PROTEIN: DNA helicase MCM9\tK10738 MCM9; DNA helicase MCM9 [EC:5.6.2.4]"
					},
					{
						"name":"100622274 HNRNPUL1; LOW QUALITY PROTEIN: heterogeneous nuclear ribonucleoprotein U-like protein 1\tK15047 HNRNPUL1; heterogeneous nuclear ribonucleoprotein U-like protein 1"
					},
					{
						"name":"100620658 HNRNPUL2; LOW QUALITY PROTEIN: heterogeneous nuclear ribonucleoprotein U-like protein 2\tK28611 HNRNPUL2; heterogeneous nuclear ribonucleoprotein U-like protein 2"
					},
					{
						"name":"100518897 MRNIP; MRN complex-interacting protein isoform X1\tK28623 MRNIP; MRN complex-interacting protein"
					},
					{
						"name":"100627173 CXHXorf57; uncharacterized protein CXorf57 homolog\tK29002 RADX; RPA-related protein RADX"
					},
					{
						"name":"100515053 RBM6; RNA-binding protein 6 isoform X1\tK29038 RBM6; RNA-binding protein 6"
					}
					]
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"DNA-PK complex",
					"children":[
					{
						"name":"100154200 XRCC6; X-ray repair cross-complementing protein 6\tK10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1"
					},
					{
						"name":"100514133 XRCC5; X-ray repair cross-complementing protein 5 isoform X1\tK10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2"
					},
					{
						"name":"100156379 PRKDC; DNA-dependent protein kinase catalytic subunit isoform X1\tK06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]"
					}
					]
				},
				{
					"name":"MRX complex",
					"children":[
					{
						"name":"100516687 MRE11; LOW QUALITY PROTEIN: double-strand break repair protein MRE11\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"100522666 RAD50; DNA repair protein RAD50\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					}
					]
				},
				{
					"name":"DNA Ligase 4 complex",
					"children":[
					{
						"name":"100155891 LIG4; DNA ligase 4\tK10777 LIG4; DNA ligase 4 [EC:6.5.1.1]"
					},
					{
						"name":"100514895 XRCC4; DNA repair protein XRCC4 isoform X1\tK10886 XRCC4; DNA-repair protein XRCC4"
					},
					{
						"name":"110255182 NHEJ1; LOW QUALITY PROTEIN: non-homologous end-joining factor 1\tK10980 NHEJ1; non-homologous end-joining factor 1"
					}
					]
				},
				{
					"name":"X-family DNA polymerases",
					"children":[
					{
						"name":"100153781 POLL; DNA polymerase lambda isoform X1\tK03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]"
					},
					{
						"name":"100515113 POLM; DNA-directed DNA\/RNA polymerase mu isoform X1\tK03513 POLM; DNA polymerase mu [EC:2.7.7.7]"
					},
					{
						"name":"100518694 DNTT; DNA nucleotidylexotransferase isoform X2\tK00977 DNTT; DNA nucleotidylexotransferase [EC:2.7.7.31]"
					},
					{
						"name":"100526021 POLB; LOW QUALITY PROTEIN: DNA polymerase beta\tK02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]"
					}
					]
				},
				{
					"name":"Other NHEJ factors",
					"children":[
					{
						"name":"387596 APTX; aprataxin\tK10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]"
					},
					{
						"name":"100516073 APLF; aprataxin and PNK-like factor isoform X1\tK13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-]"
					},
					{
						"name":"100512855 DCLRE1C; protein artemis\tK10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-]"
					},
					{
						"name":"100157860 TDP2; tyrosyl-DNA phosphodiesterase 2\tK19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]"
					},
					{
						"name":"100627122 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1 isoform X1\tK23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1"
					},
					{
						"name":"100511862 PWWP domain-containing protein MUM1 isoform X1\tK23386 PWWP3; PWWP domain-containing DNA repair factor 3"
					},
					{
						"name":"100739251 MUM1L1; PWWP domain-containing protein MUM1L1\tK23386 PWWP3; PWWP domain-containing DNA repair factor 3"
					},
					{
						"name":"110257701 PWWP domain-containing protein MUM1L1-like\tK23386 PWWP3; PWWP domain-containing DNA repair factor 3"
					},
					{
						"name":"110257816 PWWP domain-containing protein MUM1L1-like\tK23386 PWWP3; PWWP domain-containing DNA repair factor 3"
					},
					{
						"name":"110258085 CUNH9orf142; protein PAXX isoform X1\tK25772 PAXX; protein PAXX"
					},
					{
						"name":"100523873 C18H7orf49; modulator of retrovirus infection homolog isoform X3\tK26155 CYREN; cell cycle regulator of non-homologous end joining"
					},
					{
						"name":"100511444 JMJD8; jmjC domain-containing protein 8\tK25792 JMJD8; jumonji domain-containing protein 8"
					},
					{
						"name":"100739819 C17H20orf196; uncharacterized protein C20orf196 homolog isoform X1\tK26128 SHLD1; shieldin complex subunit 1"
					},
					{
						"name":"100625894 FAM35A; protein FAM35A isoform X1\tK26129 SHLD2; shieldin complex subunit 2"
					},
					{
						"name":"100514664 BEND4; BEN domain-containing protein 4 isoform X1\tK27845 BEND4; BEN domain-containing protein 4"
					},
					{
						"name":"100515778 IFFO1; intermediate filament family orphan 1 isoform X1\tK28738 IFFO; non-homologous end joining factor IFFO"
					},
					{
						"name":"100737107 IFFO2; intermediate filament family orphan 2 isoform X1\tK28738 IFFO; non-homologous end joining factor IFFO"
					}
					]
				}
				]
			},
			{
				"name":"FA (Fanconi anemia) pathway",
				"children":[
				{
					"name":"FA core complex",
					"children":[
					{
						"name":"100621453 FANCA; Fanconi anemia group A protein isoform X4\tK10888 FANCA; fanconi anemia group A protein"
					},
					{
						"name":"100156438 FANCB; Fanconi anemia group B protein\tK10889 FANCB; fanconi anemia group B protein"
					},
					{
						"name":"102158362 FANCC; Fanconi anemia group C protein isoform X2\tK10890 FANCC; fanconi anemia group C protein"
					},
					{
						"name":"100519701 FANCF; Fanconi anemia group F protein\tK10893 FANCF; fanconi anemia group F protein"
					},
					{
						"name":"100511060 FANCG; Fanconi anemia group G protein isoform X2\tK10894 FANCG; fanconi anemia group G protein"
					},
					{
						"name":"100526164 FANCL; E3 ubiquitin-protein ligase FANCL isoform X1\tK10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]"
					},
					{
						"name":"100155917 FANCM; Fanconi anemia group M protein isoform X1\tK10896 FANCM; fanconi anemia group M protein"
					},
					{
						"name":"100621643 FAAP24; Fanconi anemia core complex-associated protein 24\tK10898 FAAP24; fanconi anemia-associated protein"
					},
					{
						"name":"100625661 FAAP100; LOW QUALITY PROTEIN: Fanconi anemia core complex-associated protein 100\tK10993 FAAP100; fanconi anemia core complex 100 kDa subunit"
					}
					]
				},
				{
					"name":"FA core complex binding factors",
					"children":[
					{
						"name":"100499567 HES1; transcription factor HES-1\tK06054 HES1; hairy and enhancer of split 1"
					},
					{
						"name":"100522376 APITD1; centromere protein S\tK11511 APITD1; centromere protein S"
					},
					{
						"name":"100525658 UBE2T; ubiquitin-conjugating enzyme E2 T isoform X1\tK13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]"
					}
					]
				},
				{
					"name":"Bloom's syndrome complex (BTR)",
					"children":[
					{
						"name":"100141304 BLM; Bloom syndrome protein\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"100155140 TOP3B; LOW QUALITY PROTEIN: DNA topoisomerase 3-beta-1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"110256129 TOP3A; DNA topoisomerase 3-alpha isoform X1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"100517963 RMI1; recQ-mediated genome instability protein 1\tK10990 RMI1; RecQ-mediated genome instability protein 1"
					},
					{
						"name":"100518832 RMI2; recQ-mediated genome instability protein 2\tK15365 RMI2; RecQ-mediated genome instability protein 2"
					}
					]
				},
				{
					"name":"FANCD2-I complex",
					"children":[
					{
						"name":"100522343 FANCD2; Fanconi anemia group D2 protein isoform X1\tK10891 FANCD2; fanconi anemia group D2 protein"
					},
					{
						"name":"100156260 FANCI; Fanconi anemia group I protein\tK10895 FANCI; fanconi anemia group I protein"
					}
					]
				},
				{
					"name":"Downstream FA components",
					"children":[
					{
						"name":"100049662 BRCA1; breast cancer type 1 susceptibility protein isoform X15\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"100624979 BRCA2; LOW QUALITY PROTEIN: breast cancer type 2 susceptibility protein\tK08775 BRCA2; breast cancer 2 susceptibility protein"
					},
					{
						"name":"100525359 BRIP1; LOW QUALITY PROTEIN: Fanconi anemia group J protein\tK15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]"
					},
					{
						"name":"100523630 PALB2; partner and localizer of BRCA2 isoform X3\tK10897 PALB2; partner and localizer of BRCA2"
					}
					]
				},
				{
					"name":"Other FA pathway factors",
					"children":[
					{
						"name":"100525727 FAN1; fanconi-associated nuclease 1 isoform X4\tK15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]"
					},
					{
						"name":"100141309 RAD51; DNA repair protein RAD51 homolog 1\tK04482 RAD51; DNA repair protein RAD51"
					},
					{
						"name":"100518577 RAD51C; DNA repair protein RAD51 homolog 3 isoform X5\tK10870 RAD51L2; RAD51-like protein 2"
					},
					{
						"name":"100514221 TELO2; telomere length regulation protein TEL2 homolog isoform X1\tK11137 TELO2; telomere length regulation protein"
					},
					{
						"name":"100523071 USP1; ubiquitin carboxyl-terminal hydrolase 1\tK11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]"
					},
					{
						"name":"100518629 WDR48; WD repeat-containing protein 48 isoform X1\tK15361 WDR48; WD repeat-containing protein 48"
					}
					]
				}
				]
			},
			{
				"name":"Other DSBR factors",
				"children":[
				{
					"name":"Protein phosphatase 6",
					"children":[
					{
						"name":"100153256 PPP6C; serine\/threonine-protein phosphatase 6 catalytic subunit\tK15498 PPP6C; serine\/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"100514409 PPP6R1; LOW QUALITY PROTEIN: serine\/threonine-protein phosphatase 6 regulatory subunit 1\tK15499 PPP6R1; serine\/threonine-protein phosphatase 6 regulatory subunit 1"
					},
					{
						"name":"100517282 PPP6R2; serine\/threonine-protein phosphatase 6 regulatory subunit 2\tK15500 PPP6R2; serine\/threonine-protein phosphatase 6 regulatory subunit 2"
					},
					{
						"name":"100524129 PPP6R3; serine\/threonine-protein phosphatase 6 regulatory subunit 3 isoform X1\tK15501 PPP6R3; serine\/threonine-protein phosphatase 6 regulatory subunit 3"
					},
					{
						"name":"100152333 ANKRD28; serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A\tK15502 ANKRD28; serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A"
					},
					{
						"name":"100620944 ANKRD44; serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B isoform X6\tK15503 ANKRD44; serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B"
					},
					{
						"name":"100519313 ANKRD52; serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C isoform X1\tK15504 ANKRD52; serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C"
					}
					]
				},
				{
					"name":"Ubiquitin ligases",
					"children":[
					{
						"name":"100153408 RNF8; E3 ubiquitin-protein ligase RNF8 isoform X2\tK10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]"
					},
					{
						"name":"102167889 LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF168\tK20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31]"
					},
					{
						"name":"110256406 RNF168; E3 ubiquitin-protein ligase RNF168 isoform X1\tK20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31]"
					},
					{
						"name":"100739168 RNF169; E3 ubiquitin-protein ligase RNF169\tK20805 RNF169; E3 ubiquitin-protein ligase RNF169 [EC:2.3.2.31]"
					},
					{
						"name":"100737018 HERC2; E3 ubiquitin-protein ligase HERC2 isoform X1\tK10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]"
					}
					]
				},
				{
					"name":"Others",
					"children":[
					{
						"name":"100522033 WRAP53; telomerase Cajal body protein 1\tK23314 WRAP53; telomerase Cajal body protein 1"
					},
					{
						"name":"100621246 TPRN; taperin\tK24164 TPRN; taperin"
					},
					{
						"name":"100513075 ZCWPW1; zinc finger CW-type PWWP domain protein 1 isoform X2\tK24688 ZCWPW1; zinc finger CW-type PWWP domain protein 1"
					},
					{
						"name":"100517617 WDR70; WD repeat-containing protein 70 isoform X1\tK24752 WDR70; WD repeat-containing protein 70"
					},
					{
						"name":"100519285 WDR76; WD repeat-containing protein 76 isoform X2\tK24755 WDR76; WD repeat-containing protein 76"
					},
					{
						"name":"106504109 HMCES; embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein\tK28434 HMCES; abasic site processing protein HMCES"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases",
				"children":[
				{
					"name":"100153104 POLH; DNA polymerase eta isoform X2\tK03509 POLH; DNA polymerase eta [EC:2.7.7.7]"
				},
				{
					"name":"100525374 POLI; DNA polymerase iota isoform X1\tK03510 POLI; DNA polymerase iota [EC:2.7.7.7]"
				},
				{
					"name":"100518650 POLK; LOW QUALITY PROTEIN: DNA polymerase kappa\tK03511 POLK; DNA polymerase kappa [EC:2.7.7.7]"
				},
				{
					"name":"100522795 REV1; DNA repair protein REV1 isoform X1\tK03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]"
				}
				]
			},
			{
				"name":"B-family DNA polymerases",
				"children":[
				{
					"name":"100513963 REV3L; DNA polymerase zeta catalytic subunit isoform X1\tK02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]"
				}
				]
			},
			{
				"name":"A-family DNA polymerase",
				"children":[
				{
					"name":"102157420 POLN; DNA polymerase nu isoform X1\tK16618 POLN; DNA polymerase nu [EC:2.7.7.7]"
				}
				]
			},
			{
				"name":"Rad6 epistasis group",
				"children":[
				{
					"name":"100154142 UBE2A; ubiquitin-conjugating enzyme E2 A\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]"
				},
				{
					"name":"100156381 ubiquitin-conjugating enzyme E2 B-like isoform X1\tK10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]"
				},
				{
					"name":"100513527 UBE2B; ubiquitin-conjugating enzyme E2 B\tK10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]"
				},
				{
					"name":"100217383 RAD18; E3 ubiquitin-protein ligase RAD18\tK10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]"
				},
				{
					"name":"100520979 HLTF; helicase-like transcription factor isoform X1\tK15711 SMARCA3; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]"
				},
				{
					"name":"100512077 UBE2V1; ubiquitin-conjugating enzyme E2 variant 1\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"100627960 UBE2V2; ubiquitin-conjugating enzyme E2 variant 2\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"100154647 ubiquitin-conjugating enzyme E2 N-like\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				},
				{
					"name":"100519842 UBE2N; LOW QUALITY PROTEIN: ubiquitin-conjugating enzyme E2 N\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				}
				]
			},
			{
				"name":"Other TLS factors",
				"children":[
				{
					"name":"692192 PCNA; proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
				},
				{
					"name":"100514810 PCLAF; PCNA-associated factor\tK28763 PCLAF; PCNA-associated factor"
				},
				{
					"name":"100523000 PARPBP; PCNA-interacting partner isoform X2\tK27412 PARPBP; PCNA-interacting partner"
				},
				{
					"name":"100155479 SPRTN; sprT-like domain-containing protein Spartan\tK24051 SPRTN; SprT-like domain-contaning protein Spartan"
				},
				{
					"name":"100621048 GCNA; acidic repeat-containing protein\tK26957 GCNA; germ cell nuclear acidic protein"
				},
				{
					"name":"100301558 DPPA5; developmental pluripotency-associated 5 protein\tK28975 DPPA5; developmental pluripotency-associated protein 5"
				}
				]
			}
			]
		},
		{
			"name":"Check point factors",
			"children":[
			{
				"name":"Rad9-Hus1-Rad1 complex",
				"children":[
				{
					"name":"100512330 RAD9A; cell cycle checkpoint control protein RAD9A isoform X1\tK10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]"
				},
				{
					"name":"100738069 RAD9B; cell cycle checkpoint control protein RAD9B isoform X1\tK10995 RAD9B; cell cycle checkpoint control protein RAD9B"
				},
				{
					"name":"100192318 HUS1; checkpoint protein HUS1\tK10903 HUS1; HUS1 checkpoint protein"
				},
				{
					"name":"100513318 RAD1; cell cycle checkpoint protein RAD1\tK02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]"
				}
				]
			},
			{
				"name":"HRAD17(Rad24)-RFC complex",
				"children":[
				{
					"name":"100515763 RAD17; cell cycle checkpoint protein RAD17 isoform X1\tK06662 HRAD17; cell cycle checkpoint protein"
				},
				{
					"name":"100620242 RFC2; replication factor C subunit 2 isoform X1\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"106504063 RFC4; replication factor C subunit 4 isoform X1\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"100153965 RFC5; replication factor C subunit 5\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"100156440 RFC3; replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
				}
				]
			},
			{
				"name":"Rad17-Mec3-Ddc1 complex",
				"children":[
				{
					"name":"100513318 RAD1; cell cycle checkpoint protein RAD1\tK02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]"
				}
				]
			},
			{
				"name":"FPC (fork protection complex)",
				"children":[
				{
					"name":"100153268 TIPIN; TIMELESS-interacting protein\tK10998 TIPIN; replication fork protection complex subunit TIPIN\/Csm3\/Swi3"
				},
				{
					"name":"100525928 CLSPN; claspin isoform X1\tK25773 CLSPN; claspin"
				}
				]
			},
			{
				"name":"Triple T complex",
				"children":[
				{
					"name":"100514221 TELO2; telomere length regulation protein TEL2 homolog isoform X1\tK11137 TELO2; telomere length regulation protein"
				},
				{
					"name":"100154931 TTI1; LOW QUALITY PROTEIN: TELO2-interacting protein 1 homolog\tK20403 TTI1; TELO2-interacting protein 1"
				},
				{
					"name":"100526252 TTI2; TELO2-interacting protein 2\tK23115 TTI2; TELO2-interacting protein 2"
				}
				]
			},
			{
				"name":"BAG6-UBL4A-GET4 complex",
				"children":[
				{
					"name":"100153950 BAG6; large proline-rich protein BAG6\tK23390 BAG6; large proline-rich protein BAG6"
				},
				{
					"name":"100157648 UBL4B; ubiquitin-like protein 4B\tK23388 UBL4; ubiquitin-like protein 4"
				},
				{
					"name":"100622730 UBL4A; ubiquitin-like protein 4A isoform X1\tK23388 UBL4; ubiquitin-like protein 4"
				},
				{
					"name":"100520727 GET4; Golgi to ER traffic protein 4 homolog isoform X1\tK23387 GET4; golgi to ER traffic protein 4"
				}
				]
			},
			{
				"name":"SOSS complex",
				"children":[
				{
					"name":"100152330 INTS3; integrator complex subunit 3\tK13140 INTS3; integrator complex subunit 3 (SOSS complex subunit A)"
				},
				{
					"name":"100154321 NABP2; SOSS complex subunit B1\tK28889 NABP; SOSS complex subunit B"
				},
				{
					"name":"100155066 NABP1; SOSS complex subunit B2\tK28889 NABP; SOSS complex subunit B"
				},
				{
					"name":"100513906 INIP; SOSS complex subunit C\tK28890 INIP; SOSS complex subunit C"
				}
				]
			},
			{
				"name":"Other check point factors",
				"children":[
				{
					"name":"100516227 ATR; serine\/threonine-protein kinase ATR\tK06640 ATR; serine\/threonine-protein kinase ATR [EC:2.7.11.1]"
				},
				{
					"name":"100523399 ATRIP; ATR-interacting protein\tK10905 ATRIP; ATR interacting protein"
				},
				{
					"name":"100622990 ETAA1; ewing's tumor-associated antigen 1 isoform X1\tK28856 ETAA1; Ewing's tumor-associated antigen 1"
				},
				{
					"name":"100101922 ATM; serine-protein kinase ATM\tK04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]"
				},
				{
					"name":"397276 TP53; cellular tumor antigen p53\tK04451 TP53; tumor protein p53"
				},
				{
					"name":"100511709 CHEK1; serine\/threonine-protein kinase Chk1\tK02216 CHEK1; serine\/threonine-protein kinase CHEK1 [EC:2.7.11.1]"
				},
				{
					"name":"100192447 CHEK2; serine\/threonine-protein kinase Chk2\tK06641 CHEK2; serine\/threonine-protein kinase CHEK2 [EC:2.7.11.1]"
				},
				{
					"name":"100737380 CDC25A; M-phase inducer phosphatase 1 isoform X1\tK06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]"
				},
				{
					"name":"100329127 CDC25B; M-phase inducer phosphatase 2\tK05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]"
				},
				{
					"name":"100144474 CDC25C; M-phase inducer phosphatase 3\tK05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]"
				},
				{
					"name":"100048964 YWHAQ; 14-3-3 protein theta\tK16197 YWHAB_Q_Z; 14-3-3 protein beta\/theta\/zeta"
				},
				{
					"name":"100153160 YWHAB; 14-3-3 protein beta\/alpha\tK16197 YWHAB_Q_Z; 14-3-3 protein beta\/theta\/zeta"
				},
				{
					"name":"780440 YWHAZ; 14-3-3 protein zeta\/delta\tK16197 YWHAB_Q_Z; 14-3-3 protein beta\/theta\/zeta"
				},
				{
					"name":"100155504 YWHAH; 14-3-3 protein eta\tK16198 YWHAG_H; 14-3-3 protein gamma\/eta"
				},
				{
					"name":"100523057 YWHAG; 14-3-3 protein gamma\tK16198 YWHAG_H; 14-3-3 protein gamma\/eta"
				},
				{
					"name":"100620600 YWHAE; 14-3-3 protein epsilon isoform X1\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"100521067 NAV2; neuron navigator 2 isoform X1\tK19483 NAV2; neuron navigator 2 [EC:5.6.2.4]"
				},
				{
					"name":"100048934 WEE2; wee1-like protein kinase 2\tK06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]"
				},
				{
					"name":"100521487 WEE1; wee1-like protein kinase isoform X1\tK06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]"
				},
				{
					"name":"100620648 PER1; period circadian protein homolog 1 isoform X1\tK21944 PER1; period circadian protein 1"
				},
				{
					"name":"100154609 PER2; period circadian protein homolog 2 isoform X1\tK02633 PER2; period circadian protein 2"
				},
				{
					"name":"100627898 PER3; period circadian protein homolog 3 isoform X1\tK21945 PER3; period circadian protein 3"
				},
				{
					"name":"100144453 MDC1; mediator of DNA damage checkpoint protein 1\tK20780 MDC1; mediator of DNA damage checkpoint protein 1"
				},
				{
					"name":"100158187 PLS3; LOW QUALITY PROTEIN: plastin-3\tK17336 PLS3; plastin-3"
				},
				{
					"name":"100522657 AEN; apoptosis-enhancing nuclease\tK18340 AEN; apoptosis-enhancing nuclease [EC:3.1.-.-]"
				},
				{
					"name":"397250 PLK3; serine\/threonine-protein kinase PLK3\tK08862 PLK3; polo-like kinase 3 [EC:2.7.11.21]"
				},
				{
					"name":"100523719 PLK5; inactive serine\/threonine-protein kinase PLK5 isoform X4\tK19596 PLK5; inactive serine\/threonine-protein kinase PLK5"
				},
				{
					"name":"100156672 NEK5; serine\/threonine-protein kinase Nek5 isoform X1\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]"
				},
				{
					"name":"100520589 NEK1; serine\/threonine-protein kinase Nek1 isoform X1\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]"
				},
				{
					"name":"106504146 NEK4; serine\/threonine-protein kinase Nek4 isoform X1\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]"
				},
				{
					"name":"100622627 NEK10; serine\/threonine-protein kinase Nek10 isoform X1\tK20879 NEK10; serine\/threonine-protein kinase Nek10 [EC:2.7.11.1]"
				},
				{
					"name":"100739585 NEK11; serine\/threonine-protein kinase Nek11 isoform X1\tK20880 NEK11; serine\/threonine-protein kinase Nek11 [EC:2.7.11.1]"
				},
				{
					"name":"100620553 DONSON; protein downstream neighbor of Son\tK22422 DONSON; protein downstream neighbor of Son"
				},
				{
					"name":"100513584 KANK3; KN motif and ankyrin repeat domain-containing protein 3 isoform X1\tK22808 KANK; KN motif and ankyrin repeat domain-containing protein"
				},
				{
					"name":"100523255 KANK4; KN motif and ankyrin repeat domain-containing protein 4 isoform X1\tK22808 KANK; KN motif and ankyrin repeat domain-containing protein"
				},
				{
					"name":"100626649 KANK1; KN motif and ankyrin repeat domain-containing protein 1 isoform X1\tK22808 KANK; KN motif and ankyrin repeat domain-containing protein"
				},
				{
					"name":"110255324 KANK2; KN motif and ankyrin repeat domain-containing protein 2 isoform X1\tK22808 KANK; KN motif and ankyrin repeat domain-containing protein"
				},
				{
					"name":"100519570 KLLN; LOW QUALITY PROTEIN: killin\tK23389 KLLN; killin"
				},
				{
					"name":"100625890 SLFN11; schlafen family member 11 isoform X1\tK24458 SLFN11; schlafen family member 11 [EC:3.6.-.-]"
				},
				{
					"name":"100154336 CHMP4C; charged multivesicular body protein 4c\tK24782 CHMP4C; charged multivesicular body protein 4C"
				},
				{
					"name":"100625338 VPS4B; vacuolar protein sorting-associated protein 4B\tK12196 VPS4; vacuolar protein-sorting-associated protein 4"
				},
				{
					"name":"100627841 VPS4A; vacuolar protein sorting-associated protein 4A\tK12196 VPS4; vacuolar protein-sorting-associated protein 4"
				},
				{
					"name":"100154961 ZFYVE19; abscission\/NoCut checkpoint regulator\tK24778 ZFYVE19; abscission\/NoCut checkpoint regulator"
				},
				{
					"name":"100524888 SDE2; LOW QUALITY PROTEIN: protein SDE2 homolog\tK25059 SDE2; replication stress response regulator SDE2"
				},
				{
					"name":"100515537 KRCC1; lysine-rich coiled-coil protein 1\tK29003 KRCC1; lysine-rich coiled-coil protein 1"
				}
				]
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerases",
				"children":[
				{
					"name":"110256415 POLQ; DNA polymerase theta isoform X1\tK02349 POLQ; DNA polymerase theta [EC:2.7.7.7]"
				},
				{
					"name":"100520635 MYBBP1A; myb-binding protein 1A isoform X2\tK02331 POL5; DNA polymerase phi [EC:2.7.7.7]"
				},
				{
					"name":"100515586 PRIMPOL; DNA-directed primase\/polymerase protein isoform X1\tK22761 PRIMPOL; DNA-directed primase\/polymerase protein [EC:2.7.7.102 2.7.7.7]"
				}
				]
			},
			{
				"name":"Nucleases",
				"children":[
				{
					"name":"100155669 TREX1; three-prime repair exonuclease 1\tK10790 TREX1; three prime repair exonuclease 1 [EC:3.1.11.2]"
				},
				{
					"name":"100621378 TREX2; three prime repair exonuclease 2\tK10791 TREX2; three prime repair exonuclease 2 [EC:3.1.11.2]"
				},
				{
					"name":"100156734 DCLRE1A; DNA cross-link repair 1A protein\tK15340 DCLRE1A; DNA cross-link repair 1A protein"
				},
				{
					"name":"100516672 DCLRE1B; 5' exonuclease Apollo\tK15341 DCLRE1B; DNA cross-link repair 1B protein [EC:3.1.-.-]"
				},
				{
					"name":"100511388 EXO5; exonuclease V\tK17815 EXO5; exonuclease V [EC:3.1.-.-]"
				},
				{
					"name":"100157618 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 isoform X1\tK25861 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 [EC:5.6.2.- 3.1.-.-]"
				},
				{
					"name":"100620785 ANKLE1; LOW QUALITY PROTEIN: ankyrin repeat and LEM domain-containing protein 1\tK21411 ANKLE1; ankyrin repeat and LEM domain-containing protein 1"
				}
				]
			},
			{
				"name":"Helicases",
				"children":[
				{
					"name":"100524635 HELQ; helicase POLQ-like isoform X8\tK19178 HELQ; POLQ-like helicase [EC:5.6.2.4]"
				},
				{
					"name":"100515232 ERCC6L2; DNA excision repair protein ERCC-6-like 2 isoform X1\tK20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-]"
				}
				]
			},
			{
				"name":"PSO4 complex",
				"children":[
				{
					"name":"100144769 PRPF19; pre-mRNA-processing factor 19\tK10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]"
				},
				{
					"name":"100153900 CDC5L; cell division cycle 5-like protein\tK12860 CDC5L; pre-mRNA-splicing factor CDC5\/CEF1"
				},
				{
					"name":"100154006 BCAS2; pre-mRNA-splicing factor SPF27\tK12861 BCAS2; pre-mRNA-splicing factor SPF27"
				},
				{
					"name":"100514171 PLRG1; pleiotropic regulator 1\tK12862 PLRG1; pleiotropic regulator 1"
				}
				]
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"100621855 NUDT15; LOW QUALITY PROTEIN: nucleotide triphosphate diphosphatase NUDT15\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"100624718 NUDT1; 7,8-dihydro-8-oxoguanine triphosphatase\tK17816 NUDT1; 8-oxo-dGTP diphosphatase \/ 2-hydroxy-dATP diphosphatase [EC:3.6.1.55 3.6.1.56]"
				},
				{
					"name":"100156061 NUDT18; 8-oxo-dGDP phosphatase NUDT18\tK17817 NUDT18; 8-oxo-dGDP phosphatase [EC:3.6.1.58]"
				},
				{
					"name":"100621123 DUT; deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial isoform X1\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				},
				{
					"name":"102166900 RRM1; LOW QUALITY PROTEIN: ribonucleoside-diphosphate reductase large subunit\tK10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]"
				},
				{
					"name":"100157205 RRM2B; ribonucleoside-diphosphate reductase subunit M2 B isoform X2\tK10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]"
				},
				{
					"name":"100316853 RRM2; ribonucleoside-diphosphate reductase subunit M2\tK10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair",
				"children":[
				{
					"name":"100155050 MGMT; methylated-DNA--protein-cysteine methyltransferase isoform X3\tK00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]"
				}
				]
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"100519979 UNG; uracil-DNA glycosylase\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"100153912 SMUG1; single-strand selective monofunctional uracil DNA glycosylase isoform X2\tK10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]"
					},
					{
						"name":"100525334 MPG; DNA-3-methyladenine glycosylase\tK03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]"
					},
					{
						"name":"100513867 MUTYH; adenine DNA glycosylase isoform X1\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
					},
					{
						"name":"100516255 NTHL1; endonuclease III-like protein 1 isoform X7\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases"
				},
				{
					"name":"RecJ"
				},
				{
					"name":"DNA ligase"
				},
				{
					"name":"DNA polymerase I"
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors"
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase complex (RNAP)"
					},
					{
						"name":"TRCF (transcription-repair coupling factor)"
					}
					]
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors"
				},
				{
					"name":"Molecular matchmaker"
				},
				{
					"name":"Strand discrimination factor"
				},
				{
					"name":"DNA exonucleases"
				},
				{
					"name":"DNA polymerase III holoenzyme"
				},
				{
					"name":"DNA ligase"
				},
				{
					"name":"Other MMR factors",
					"children":[
					{
						"name":"100512994 SSBP1; single-stranded DNA-binding protein, mitochondrial isoform X1\tK03111 ssb; single-strand DNA-binding protein"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"RecBC pathway proteins"
				},
				{
					"name":"RecFOR pathway proteins"
				},
				{
					"name":"AddAB pathway proteins"
				},
				{
					"name":"Other HR factor"
				},
				{
					"name":"Archaeal homologous recombinant proteins"
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"Two-component NHEJ DNA repair complex"
				},
				{
					"name":"SHIIR (short-homology-independent illegitimate recombination)",
					"children":[
					{
						"name":"Facilitator"
					},
					{
						"name":"Supressor"
					}
					]
				},
				{
					"name":"SHDIR (short-homology-dependent illegitimate recombination)",
					"children":[
					{
						"name":"RecET pathway"
					},
					{
						"name":"Facilitator"
					},
					{
						"name":"Supressor"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases"
			},
			{
				"name":"Other SOS response factors",
				"children":[
				{
					"name":"100512994 SSBP1; single-stranded DNA-binding protein, mitochondrial isoform X1\tK03111 ssb; single-strand DNA-binding protein"
				}
				]
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerase"
			},
			{
				"name":"DNA helicases"
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"100621855 NUDT15; LOW QUALITY PROTEIN: nucleotide triphosphate diphosphatase NUDT15\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"100621123 DUT; deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial isoform X1\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				}
				]
			},
			{
				"name":"Others"
			}
			]
		}
		]
	}
	]
}