+D	AMR gene	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Antimicrobial Resistance Genes - Bacillus subtilis subsp. subtilis 168</h2>
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A<b>Gene variants</b>
B  beta-Lactamase genes
C    Class A [MT]
C    Class D [MT]
C    Class C [MT]
C    Class B [MT]
B  Aminoglycoside resistance genes
C    N-Acetyltransferases
D      BSU21630 yokD; AAC(3) family N-acetyltransferase	K00662 aacC; aminoglycoside 3-N-acetyltransferase [EC:2.3.1.81] 
C    Other acetyltransferases
D      BSU40740 yyaR; hypothetical protein	K19273 sat4; streptothricin acetyltransferase [EC:2.3.-.-] 
C    O-Nucleotidyltransferases
D      BSU26790 aadK; aminoglycoside 6-adenylyltransferase	K05593 aadK; aminoglycoside 6-adenylyltransferase [EC:2.7.7.-] 
C    O-Phosphotransferases
C    16S rRNA methyltransferases
B  Tetracycline resistance genes
C    Transporters
D      BSU40770 tetB; tetracycline resistance protein	K08168 tetB; MFS transporter, DHA2 family, metal-tetracycline-proton antiporter 
C    Others
B  Macrolide resistance genes
C    23S rRNA methyltransferases
C    Transporters
D      BSU05610 vmlR; nucleotide-binding protein ExpZ	K18231 msr; macrolide transport system ATP-binding/permease protein 
C    Others
D      BSU02520 ycbJ; hypothetical protein	K06979 mph; macrolide phosphotransferase 
B  Phenicol resistance genes
C    Transporters
C    Acetyltransferases
C    Phosphotransferase
C    23S rRNA methyltransferase
B  Sulfonamide resistance genes
C    Dihydropteroate synthase
B  Trimethoprim resistance genes
C    Dihydrofolate reductases
B  Quinolone resistance genes
C    Transporter
C    Other
B  Rifamycin resistance genes
C    ADP-ribosyl transferases
C    Oxygenases
B  Fosfomycin resistance genes
C    Transferases
C    Others
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A<b>Gene sets</b>
B  beta-Lactam resistance modules
C    Methicillin resistance [MD:M00625]
C    beta-Lactam resistance, Bla system [MD:M00627]
D      BSU18800 penP; beta-lactamase	K17836 penP; beta-lactamase class A [EC:3.5.2.6] 
C    Imipenem resistance, repression of porin OprD [MD:M00745]
B  Vancomycin resistance modules
C    Vancomycin resistance, D-Ala-D-Lac type [MD:M00651]
D      BSU19620 yodJ; carboxypeptidase YodJ	K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] 
C    Vancomycin resistance, D-Ala-D-Ser type [MD:M00652]
D      B  Tetracycline resistance
C    Tetracycline resistance, efflux pump Tet38 [MD:M00704]
D      BSU40770 tetB; tetracycline resistance protein	K08168 tetB; MFS transporter, DHA2 family, metal-tetracycline-proton antiporter 
B  CAMP resistance modules
C    Cationic antimicrobial peptide (CAMP) resistance, dltABCD operon [MD:M00725]
D      BSU38500 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1	K03367 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13] 
D      BSU38510 dltB; protein DltB	K03739 dltB; membrane protein involved in D-alanine export 
D      BSU38520 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2	K14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13] 
D      BSU38530 dltD; poly D-alanine transfer protein DltD	K03740 dltD; D-alanine transfer protein 
C    Cationic antimicrobial peptide (CAMP) resistance, lysyl-phosphatidylglycerol (L-PG) synthase MprF [MD:M00726]
D      BSU08425 mprF; phosphatidylglycerol lysyltransferase	K14205 mprF; phosphatidylglycerol lysyltransferase [EC:2.3.2.3] 
C    Cationic antimicrobial peptide (CAMP) resistance, VraFG transporter [MD:M00730]
C    Cationic antimicrobial peptide (CAMP) resistance, protease PgtE [MD:M00744]
B  Multipdrug resistance modules
C    Multidrug resistance, efflux pump MexAB-OprM [MD:M00718]
C    Multidrug resistance, efflux pump MexCD-OprJ [MD:M00639]
C    Multidrug resistance, efflux pump MexEF-OprN [MD:M00641]
C    Multidrug resistance, efflux pump MexJK-OprM [MD:M00642]
C    Multidrug resistance, efflux pump MexXY-OprM [MD:M00643]
C    Multidrug resistance, efflux pump MexPQ-OpmE [MD:M00769]
C    Multidrug resistance, efflux pump AdeABC [PATH:map01501] [MD:M00649]
C    Multidrug resistance, efflux pump AcrEF-TolC [MD:M00696]
C    Multidrug resistance, efflux pump MdtEF-TolC [MD:M00697]
C    Multidrug resistance, efflux pump BpeEF-OprC [MD:M00698]
C    Multidrug resistance, efflux pump AbcA [MD:M00700]
D      BSU05370 ydfD; GntR family transcriptional regulator	K18907 norG; GntR family transcriptional regulator, regulator for abcA and norABC 
D      BSU34820 bmrA; multidrug resistance ABC transporter ATP-binding/permease protein BmrA	K18104 abcA; ATP-binding cassette, subfamily B, bacterial AbcA/BmrA [EC:7.6.2.2] 
C    Multidrug resistance, efflux pump NorB [MD:M00702]
D      BSU05370 ydfD; GntR family transcriptional regulator	K18907 norG; GntR family transcriptional regulator, regulator for abcA and norABC 
C    Multidrug resistance, efflux pump QacA [MD:M00714]
C    Multidrug resistance, efflux pump MepA [MD:M00705]
C    Multidrug resistance, repression of porin OmpF [MD:M00746]
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#Last updated: December 28, 2017
#<br>See also: Antimicrobial resistance in <a href="/kegg/genome/pathogen.html">KEGG Pathogen</a>