+E Polyketide biosynthesis proteins KO
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Polyketide Biosynthesis Proteins - Escherichia coli O6:K15:H31 536 (UPEC)
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APolyketide synthase (PKS)
B Modular type I PKS
C cis-AT PKS
D Erythronolide PKS
D Oleandomycin synthase
D Pikromycin PKS
D Avermectin PKS
D Tylactone synthase
D Protomycinolide IV synthase
D Niddamycin PKS
D Rapamycin PKS
D Immunomycin PKS
D Ansamitocin PKS
D Rifamycin PKS
D Polyene macrolide PKS
D Pimaricinolide synthase
D Candicidin PKS
D Soraphen PKS
D Stigmatellin PKS
D Mycolactone PKS
D Coelimycin PKS
D Aureothin PKS
D Spectinabilin PKS
D Phthiocerol / Phenolphthiocerol PKS
C trans-AT PKS
D Bacillanene hybrid PKS-NRPS
D Chivosazol hybrid PKS-NRPS
E ------ chiPKS; chivosazol hybrid polyketide synthase / nonribosomal peptide synthetase [SCL:sce4137 sce4136 sce4135 sce4134 sce4133]
D Macrolactin PKS
D Difficidin PKS
D Rhizoxin hybrid PKS-NRPS
D Myxovirescin hybrid PKS-NRPS
E ------ taPKS; myxovirescin biosynthesis, hybrid polyketide synthase / nonribosomal peptide synthetase [MXA:MXAN_3935 MXAN_3933 MXAN_3932]
D Albicidin synthase, hybrid PKS-NRPS
E ------ albXIII; albicidin synthase trans-acting acyltransferase AlbXIII [XAL:XALC_1516]
E ------ albPKS; albicidin synthase, hybrid polyketide synthase / nonribosomal peptide synthetase [XAL:XALC_1529 XALC_1532 XALC_1523]
D Etnangien PKS
E ------ etnPKS; etnangien polyketide synthase [SCL:sce3188 sce3189 sce3190 sce3191 sce3192 sce3193]
B Iterative type I PKS
C Fungal nonreducing PKS (NR-PKS)
C Fungal partially reducing PKS (PR-PKS)
C Fungal highly reducing PKS (HR-PKS)
C Fungal hybrid type
D Zearalenone synthase
D Asperfuranone NR/HR-PKS
E ------ AFOE; asperfuranone biosynthesis, nonreducing iterative type I polyketide synthase AfoE [ANI:ANIA_01034]
E ------ AFOG; asperfuranone biosynthesis, highly reducing iterative type I polyketide synthase AfoG [ANI:ANIA_01036]
C Bacterial type
B Type II PKS
C C9-C14 cyclized polyketide type
D Spore pigment PKS
C C7-C14 cyclized polyketide type
D Octaketide PKS
D Nonaketide PKS
D Decaketide PKS
B Type III PKS
C Plant type
C Fungal type
C Bacterial type
D ------ arsB; alkylresorcinol synthase [AVN:Avin_29550]
D ------ arsC; alkylpyrone synthase [AVN:Avin_29530]
B PKS-NRPS hybrid
C Bacterial type (modular)
D Myxalamid hybrid PKS-NRPS
D Myxothiazol hybrid PKS-NRPS
E ------ mtaPKS; myxothiazol hybrid polyketide synthase / nonribosomal peptide synthetase [SUR:STAUR_4014 STAUR_4015 STAUR_4016 STAUR_4017 STAUR_4018 STAUR_4019]
D Coronatine hybrid PKS-NRPS
D Microcystin synthetase
D Epothilone synthetase
D Bleomycin synthetase
D Colibactin synthetase
E ECP_1967 non-ribosomal peptide synthetase K26572 clbN; colibactin biosynthesis nonribosomal peptide synthase
E ECP_1979 putative polyketide synthase K26573 clbB; colibactin biosynthesis hybrid nonribosomal peptide/polyketide synthase
E ECP_1978 putative polyketide synthase K26574 clbC; colibactin biosynthesis polyketide synthase
E ECP_1973 probable peptide synthetase protein K26565 clbH; colibactin biosynthesis nonribosomal peptide synthase
E ECP_1972 probable polyketide synthase protein K26575 clbI; colibactin biosynthesis polyketide synthase
E ECP_1971 putative non-ribosomal peptide synthase K26578 clbJ; colibactin biosynthesis nonribosomal peptide synthase
E ECP_1970 putative non-ribosomal peptide synthase K26577 clbK; colibactin biosynthesis hybrid nonribosomal peptide/polyketide synthase
E ECP_1966 putative polyketide synthase K26576 clbO; colibactin biosynthesis polyketide synthase
C Fungal type (trans-ER, iterative)
D Aspyridone synthetase
C Fungal type (iterative)
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ANonribosomal peptide synthetase (NRPS)
B Linear NRPS
C ------ EASA; emericellamide biosynthesis, nonribosomal peptide synthetase EasA [ANI:ANIA_02545]
C ------ lgrABCD; linear pentadecapeptide gramicidin synthetase [BBE:BBR47_28920 BBR47_28930 BBR47_28940 BBR47_29500]
C ------ mcnABCE; cyanopeptolin synthetase [MAR:MAE_60030 MAE_60020 MAE_60010 MAE_60000]
C ACV synthetase
C Bacitracin synthetase
C Viomycin synthetase
C Pristinamycin I synthetase
C Tyrocidine synthetase
C Surfactin family lipopeptide synthetase
C Iturin family lipopeptide synthetase
C Fengycin family lipopeptide synthetase
C Arthrofactin type cyclic lipopeptide synthetase
C Vancomycin synthetase
C Nocardicin synthetase
C Bialaphos synthetase
C L-2-amino-4-methoxy-trans-3-butenoic acid synthetase
B Iterative NRPS
C Enterobactin synthetase
D ECP_0627 Isochorismatase K01252 entB; bifunctional isochorismate lyase / aryl carrier protein [EC:3.3.2.1 6.3.2.14]
D ECP_0614 enterobactin synthetase component D K02362 entD; enterobactin synthetase component D / holo-[acyl-carrier protein] synthase [EC:6.3.2.14 2.7.8.7]
D ECP_0626 2,3-dihydroxybenzoate-AMP ligase K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71]
D ECP_0618 enterobactin synthetase component F K02364 entF; L-serine---[L-seryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.72]
D ECP_0629 hypothetical protein YbdB K24147 entH; proofreading thioesterase EntH
C Bacillibactin synthetase
D ECP_0627 Isochorismatase K01252 entB; bifunctional isochorismate lyase / aryl carrier protein [EC:3.3.2.1 6.3.2.14]
D ECP_0626 2,3-dihydroxybenzoate-AMP ligase K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71]
C Gramicidin synthetase
B Nonlinear NRPS
C Yersiniabactin synthetase
D ECP_1943 yersiniabactin biosynthetic protein K04786 irp1; yersiniabactin nonribosomal peptide/polyketide synthase
D ECP_1942 yersiniabactin biosynthetic protein K04784 irp2; yersiniabactin nonribosomal peptide synthetase
D ECP_1946 yersiniabactin siderophore biosynthetic protein YbtE K04783 irp5; yersiniabactin salicyl-AMP ligase [EC:6.3.2.-]
C Pyochelin synthetase
C Mycobactin synthetase
C Vibriobactin synthetase
D ECP_0627 Isochorismatase K01252 entB; bifunctional isochorismate lyase / aryl carrier protein [EC:3.3.2.1 6.3.2.14]
D ECP_0626 2,3-dihydroxybenzoate-AMP ligase K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71]
C Myxochelin synthetase
D ECP_0626 2,3-dihydroxybenzoate-AMP ligase K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71]
D ECP_0627 Isochorismatase K01252 entB; bifunctional isochorismate lyase / aryl carrier protein [EC:3.3.2.1 6.3.2.14]
C Petrobacin synthetase
C Syringomycin synthetase
C Vanchrobactin synthetase
D ECP_0627 Isochorismatase K01252 entB; bifunctional isochorismate lyase / aryl carrier protein [EC:3.3.2.1 6.3.2.14]
D ECP_0626 2,3-dihydroxybenzoate-AMP ligase K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71]
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APolyketide tailoring proteins
B Hydrolase
B Ketoreductase
B Oxygenase
B Methylase
B Glycosyltransferase
B Halogenase
B beta-Branched incorporating proteins
B Others
C ECP_1964 putative thioesterase K26570 clbQ; colibactin biosynthesis thioesterase
C ECP_1969 probable amidase K26571 clbL; colibactin biosynthesis amidase
C ECP_1965 hypothetical protein K26579 clbP; colibactin biosynthesis peptidase
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ANonribosomal peptide tailoring proteins
B Reductase
C ECP_1944 yersiniabactin biosynthetic protein YbtU K04785 irp3; yersiniabactin synthetase, thiazolinyl reductase component
B Thioesterase
C ECP_1945 yersiniabactin biosynthetic protein YbtT K05374 irp4; yersiniabactin synthetase, thioesterase component
B Oxygenase
B Glycosyltransferase
B Aminotransferase
B Others
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#[ COMPOUND | BRITE | KEGG2 | KEGG ]
#Last updated: June 19, 2024