+C Lipid biosynthesis protein #

  Lipid Biosynthesis Proteins

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AFatty acid synthase B Animal type C K00665 FASN; fatty acid synthase, animal type [EC:2.3.1.85] B Yeast type C K00668 FAS1; fatty acid synthase subunit beta, fungi type [EC:2.3.1.86] C K00667 FAS2; fatty acid synthase subunit alpha, fungi type [EC:2.3.1.86] B Bacteria type C K11533 fas; fatty acid synthase, bacteria type [EC:2.3.1.-] B Component type C K00645 fabD, MCAT, MCT1; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] C K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180] C K18473 fabY; acetoacetyl-[acyl-carrier protein] synthase [EC:2.3.1.180] C K00647 fabB; 3-oxoacyl-[acyl-carrier-protein] synthase I [EC:2.3.1.41] C K09458 fabF, OXSM, CEM1; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] C K00059 fabG, OAR1; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] C K01716 fabA; 3-hydroxyacyl-[acyl-carrier protein] dehydratase / trans-2-decenoyl-[acyl-carrier protein] isomerase [EC:4.2.1.59 5.3.3.14] C K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59] C K16363 lpxC-fabZ; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase / 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:3.5.1.108 4.2.1.59] C K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10] C K02371 fabK; enoyl-[acyl-carrier protein] reductase II [EC:1.3.1.9] C K10780 fabL; enoyl-[acyl-carrier protein] reductase III [EC:1.3.1.104] C K00209 fabV, ter; enoyl-[acyl-carrier protein] reductase / trans-2-enoyl-CoA reductase (NAD+) [EC:1.3.1.9 1.3.1.44] C K18474 fabM; trans-2-decenoyl-[acyl-carrier protein] isomerase [EC:5.3.3.14] C K10251 HSD17B12, KAR, IFA38; 17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase [EC:1.1.1.62 1.1.1.330] C K10703 HACD, PHS1, PAS2; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134] C K07753 PECR; peroxisomal trans-2-enoyl-CoA reductase [EC:1.3.1.38] C K10258 TER, TSC13, CER10; very-long-chain enoyl-CoA reductase [EC:1.3.1.93] C K01071 MCH; medium-chain acyl-[acyl-carrier-protein] hydrolase [EC:3.1.2.21] C K10782 FATA; fatty acyl-ACP thioesterase A [EC:3.1.2.14] C K10781 FATB; fatty acyl-ACP thioesterase B [EC:3.1.2.14 3.1.2.21] C K01074 PPT; palmitoyl-protein thioesterase [EC:3.1.2.22] C K01068 ACOT1_2_4; acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2] C K11993 ACOT6; acyl-CoA thioesterase 6 [EC:3.1.2.-] C K17360 ACOT7; acyl-coenzyme A thioesterase 7 [EC:3.1.2.2] C K17361 ACOT9; acyl-coenzyme A thioesterase 9 [EC:3.1.2.-] C K12417 ACOT11; acyl-CoA thioesteraes 11 [EC:3.1.2.-] C K17362 ACOT13; acyl-coenzyme A thioesterase 13 [EC:3.1.2.-] C K10804 tesA; acyl-CoA thioesterase I [EC:3.1.2.- 3.1.2.2 3.1.1.2 3.1.1.5] C K10805 tesB; acyl-CoA thioesterase II [EC:3.1.2.-] C K10806 yciA; acyl-CoA thioesterase YciA [EC:3.1.2.-] C K12500 tesC; thioesterase III [EC:3.1.2.-] C K11608 mtfabH; mycobacterial beta-ketoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.301] C K11609 kasA; meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase I [EC:2.3.1.293] C K27070 kasB; meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase II [EC:2.3.1.294] C K11610 mabA; beta-ketoacyl ACP reductase [EC:1.1.1.100] C K27071 hadA; meromycolic acid (3R)-3-hydroxyacyl-[acyl carrier protein] dehydratase HadA [EC:4.2.1.-] C K27072 hadB; meromycolic acid (3R)-3-hydroxyacyl-[acyl carrier protein] dehydratase HadB [EC:4.2.1.-] C K27073 hadC; meromycolic acid (3R)-3-hydroxyacyl-[acyl carrier protein] dehydratase HadC [EC:4.2.1.-] C K27074 hadD; meromycolic acid (3R)-3-hydroxyacyl-[acyl carrier protein] dehydratase HadD [EC:4.2.1.-] C K11611 inhA; meromycolic acid enoyl-[acyl-carrier-protein] reductase [EC:1.3.1.118] # ADesaturase B First C K00507 SCD, desC; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1] C K03921 FAB2, SSI2, desA1; acyl-[acyl-carrier-protein] desaturase [EC:1.14.19.2 1.14.19.11 1.14.19.26] C K03922 desA2; acyl-[acyl-carrier-protein] desaturase [EC:1.14.19.2] C K22769 desA3; NADPH-dependent stearoyl-CoA 9-desaturase [EC:1.14.19.-] B Omega C K10256 FAD2; omega-6 fatty acid desaturase / acyl-lipid omega-6 desaturase (Delta-12 desaturase) [EC:1.14.19.6 1.14.19.22] C K10255 FAD6, desA; acyl-lipid omega-6 desaturase (Delta-12 desaturase) [EC:1.14.19.23 1.14.19.45] C K10257 FAD3, FAD7, FAD8, desB; acyl-lipid omega-3 desaturase [EC:1.14.19.25 1.14.19.35 1.14.19.36] C K10225 FADS3; fatty acid desaturase 3 (Delta-13 desaturase) [EC:1.14.19.-] B Front-end C K00508 E1.14.19.3; linoleoyl-CoA desaturase [EC:1.14.19.3] C K10224 FADS1; acyl-CoA (8-3)-desaturase (Delta-5 desaturase) [EC:1.14.19.44] C K10226 FADS2; acyl-CoA 6-desaturase (Delta-6 desaturase) [EC:1.14.19.3] C K12418 DES4, des1; acyl-lipid (7-3)-desaturase (Delta-4 desaturase) [EC:1.14.19.31] B Sphingolipid C K04712 DEGS; sphingolipid 4-desaturase/C4-monooxygenase [EC:1.14.19.17 1.14.18.5] B Other C K12419 FADS6; fatty acid desaturase 6 [EC:1.14.19.-] # AElongase B LCFA C K10245 ELO2; fatty acid elongase 2 [EC:2.3.1.199] C K10246 ELO3; fatty acid elongase 3 [EC:2.3.1.199] B PUFA C K10247 ELOVL1; elongation of very long chain fatty acids protein 1 [EC:2.3.1.199] C K10205 ELOVL2; elongation of very long chain fatty acids protein 2 [EC:2.3.1.199] C K10249 ELOVL4; elongation of very long chain fatty acids protein 4 [EC:2.3.1.199] C K10244 ELOVL5; elongation of very long chain fatty acids protein 5 [EC:2.3.1.199] C K10203 ELOVL6; elongation of very long chain fatty acids protein 6 [EC:2.3.1.199] C K10250 ELOVL7; elongation of very long chain fatty acids protein 7 [EC:2.3.1.199] B Unclassified C K10248 ELOVL3; elongation of very long chain fatty acids protein 3 [EC:2.3.1.199] # APolyketide synthase B Modular PKS C K10817 eryAI; 6-deoxyerythronolide-B synthase EryAI [EC:2.3.1.94] C K04786 irp1, HMWP1; yersiniabactin nonribosomal peptide/polyketide synthase C K04784 irp2, HMWP2; yersiniabactin nonribosomal peptide synthetase C K11628 mas; mycocerosic acid synthase [EC:2.3.1.111] C K12430 pks1_15; 4-hydroxyphenylalkanoate synthase [EC:2.3.1.261] C K12431 pks2; phthioceranic/hydroxyphthioceranic acid synthase [EC:2.3.1.287] C K12436 pks12; mycoketide-CoA synthase [EC:2.3.1.295] C K12437 pks13; polyketide synthase 13 C K13611 pksJ, baeJ; bacillaene biosynthesis, polyketide synthase / nonribosomal peptide synthetase PksJ/BaeJ C K13612 pksL, baeL; bacillaene polyketide synthase PksL/BaeL C K13613 pksM, baeM; bacillaene polyketide synthase PksM/BaeM C K13614 pksN, baeN; bacillaene biosynthesis, polyketide synthase / nonribosomal peptide synthetase PksN/BaeN C K13615 pksR, baeR; bacillaene polyketide synthase PksR/BaeR C K12440 ppsA; phthiocerol/phenolphthiocerol synthesis type-I polyketide synthase A [EC:2.3.1.292] C K12441 ppsB; phthiocerol/phenolphthiocerol synthesis type-I polyketide synthase B [EC:2.3.1.292] C K12442 ppsC; phthiocerol/phenolphthiocerol synthesis type-I polyketide synthase C [EC:2.3.1.292] C K12443 ppsD; phthiocerol/phenolphthiocerol synthesis type-I polyketide synthase D [EC:2.3.1.292] C K12444 ppsE; phthiocerol/phenolphthiocerol synthesis type-I polyketide synthase E [EC:2.3.1.292] B Component type C K05551 actI1, oxyA, tcmK, snoa1, aknB, mtmP; minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235] C K05552 actI2, oxyB, tcmL, snoa2, aknC, mtmK; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.- 2.3.1.260 2.3.1.235] C K05553 actI3, oxyC, tcmM, snoa3, aknD, mtmS; minimal PKS acyl carrier protein C K12420 actIII, oxyJ, snoaD, aknA; ketoreductase [EC:1.1.1.-] C K05554 actVII; aromatase [EC:4.2.1.-] C K04790 mbtC; mycobactin polyketide synthetase MbtC C K04791 mbtD; mycobactin polyketide synthetase MbtD # AAcyl-CoA synthetase B Short/medium chain acyl-CoA synthetase C K01895 ACSS1_2, acs; acetyl-CoA synthetase [EC:6.2.1.1] C K01908 ACSS3, prpE; propionyl-CoA synthetase [EC:6.2.1.17] C K01907 AACS, acsA; acetoacetyl-CoA synthetase [EC:6.2.1.16] C K23756 ACSM1, LAE; medium-chain acyl-CoA ligase / lipoate-activating enzyme [EC:6.2.1.2] C K01896 ACSM; medium-chain acyl-CoA synthetase [EC:6.2.1.2] C K23617 ACSF2; medium-chain acyl-CoA ligase, mitochondrial [EC:6.2.1.2] C K01913 AAE7, ACN1; acetate/butyrate---CoA ligase [EC:6.2.1.1 6.2.1.2] C K23618 AAE11_12; acyl-activating enzyme 11/12 [EC:6.2.1.2 6.2.1.-] C K01905 acdA; acetate---CoA ligase (ADP-forming) subunit alpha [EC:6.2.1.13] C K22224 acdB; acetate---CoA ligase (ADP-forming) subunit beta [EC:6.2.1.13] C K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13] C K12507 fadK; acyl-CoA synthetase [EC:6.2.1.-] C K13776 atuH; citronellyl-CoA synthetase [EC:6.2.1.-] B Long/very long chain acyl-CoA synthetase C K01897 ACSL, fadD; long-chain acyl-CoA synthetase [EC:6.2.1.3] C K15013 ACSBG; long-chain-fatty-acid--CoA ligase ACSBG [EC:6.2.1.3] C K03822 K03822; putative long chain acyl-CoA synthase [EC:6.2.1.-] C K12422 fadD10; long chain fatty acid CoA ligase FadD10 [EC:6.2.1.-] C K12425 fadD23; long-chain fatty acid adenylase/transferase FadD23 [EC:6.2.1.57] C K12426 fadD26; long-chain fatty acid adenylase/transferase FadD26 [EC:6.2.1.59] C K12427 fadD28; long-chain fatty acid adenylyltransferase FadD28 [EC:6.2.1.49] C K21059 fadD29; 4-hydroxyphenylalkanoate adenylyltransferase [EC:6.2.1.51] C K12429 fadD36; fatty acid CoA ligase FadD36 C K08745 SLC27A1_4, FATP1_4; solute carrier family 27 (fatty acid transporter), member 1/4 [EC:6.2.1.-] C K08746 SLC27A2, FACVL1, FATP2; solute carrier family 27 (fatty acid transporter), member 2 [EC:6.2.1.- 6.2.1.3] C K08772 SLC27A3, FATP3; solute carrier family 27 (fatty acid transporter), member 3 [EC:6.2.1.-] B Unknown C K12421 fadD9; fatty acid CoA ligase FadD9 C K12423 fadD21; fatty acid CoA ligase FadD21 C K12424 fadD22; 4-hydroxybenzoate adenylyltransferase [EC:6.2.1.50] C K12428 fadD32; fatty acid CoA ligase FadD32 C K00142 AASDH; acyl-CoA synthetase [EC:6.2.1.-] C K23875 tmlU; marinolic acid---CoA ligase [EC:6.2.1.60] C K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-] # APhospholipid acyltransferase B GPAT C K00629 GPAT1_2; glycerol-3-phosphate O-acyltransferase 1/2 [EC:2.3.1.15] C K13506 GPAT3_4, AGPAT9, AGPAT6; glycerol-3-phosphate O-acyltransferase 3/4 [EC:2.3.1.15] C K13507 GAT; glycerol-3-phosphate O-acyltransferase / dihydroxyacetone phosphate acyltransferase [EC:2.3.1.15 2.3.1.42] C K00630 ATS1; glycerol-3-phosphate O-acyltransferase [EC:2.3.1.15] C K13508 GPAT; glycerol-3-phosphate acyltransferase [EC:2.3.1.15 2.3.1.198] C K00631 plsB; glycerol-3-phosphate O-acyltransferase [EC:2.3.1.15] C K03621 plsX; phosphate acyltransferase [EC:2.3.1.274] C K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275] B LPAAT/LPLAT C K13509 AGPAT1_2; lysophosphatidate acyltransferase [EC:2.3.1.51] C K13699 ABHD5, CGI-58; abhydrolase domain-containing protein 5 [EC:2.3.1.51] C K13513 LCLAT1, AGPAT8; lysocardiolipin and lysophospholipid acyltransferase [EC:2.3.1.- 2.3.1.51] C K13511 TAZ; monolysocardiolipin acyltransferase [EC:2.3.1.-] C K13517 MBOAT1_2; lysophospholipid acyltransferase 1/2 [EC:2.3.1.51 2.3.1.-] C K13519 LPT1, ALE1; lysophospholipid acyltransferase [EC:2.3.1.51 2.3.1.23 2.3.1.-] C K13523 AGPAT3_4; lysophosphatidic acid acyltransferase / lysophosphatidylinositol acyltransferase [EC:2.3.1.51 2.3.1.-] C K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] C K13510 LPCAT1_2; lysophosphatidylcholine acyltransferase / lyso-PAF acetyltransferase [EC:2.3.1.23 2.3.1.67] C K13512 LPCAT4, AGPAT7; lysophospholipid acyltransferase [EC:2.3.1.23 2.3.1.-] C K13514 LPGAT1; lysophosphatidylglycerol acyltransferase 1 [EC:2.3.1.-] C K13515 LPCAT3, MBOAT5; lysophospholipid acyltransferase 5 [EC:2.3.1.23 2.3.1.-] C K13516 MBOAT7; lysophospholipid acyltransferase 7 [EC:2.3.1.-] # AOthers B Multifunctional type C K12432 pks3_4; mycolipanoate synthase [EC:2.3.1.252] C K12433 pks5; polyketide synthase 5 C K12434 pks7; polyketide synthase 7 C K12435 pks8; polyketide synthase 8 C K12439 pks17; polyketide synthase 17 B Component type C K12445 K12445; trans enoyl reductase [EC:1.3.1.-] ! #
#[ COMPOUND | BRITE | KEGG2 | KEGG ]
#Last updated: November 27, 2023 #
Desaturase/elongase family classification based on Hashimoto et al. (2008)