+D Messenger RNA Biogenesis KO
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Prokaryotic Defense System - Klebsiella pneumoniae Kp52.145
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ACRISPR-Cas system
B Universal Cas proteins
C BN49_1005 unnamed protein product; highly similar to CRISPR-associated protein Cas1 from Escherichia coli O139:H28 strain E24377A - ETEC (tr|A7ZQJ8) K15342 cas1; CRISP-associated protein Cas1
C BN49_1006 unnamed protein product; highly similar to CRISPR-associated protein Cas2 from Escherichia coli O55:H7 strain CB9615 - EPEC (tr|D3QPV1) K09951 cas2; CRISPR-associated protein Cas2
B Type I CRISPR-Cas system
C Type I signiture cas proteins
D BN49_0998 unnamed protein product; highly similar to CRISPR-associated helicase Cas3 from Escherichia coli B171 (tr|B3WM41) K07012 cas3; CRISPR-associated endonuclease/helicase Cas3 [EC:3.1.-.- 5.6.2.4]
C Subtype I-A factors
C Subtype I-B factors
C Subtype I-C factors
C Subtype I-D factors
C Subtype I-E factors
D BN49_0999 unnamed protein product; highly similar to putative uncharacterized protein from Escherichia coli O17:K52:H18 strain UMN026 - ExPEC (tr|B7N6Z3) K19123 casA; CRISPR system Cascade subunit CasA
D BN49_1000 unnamed protein product; highly similar to CRISPR-associated protein from Escherichia coli O44:H18 strain 042 - EAEC (tr|D3GRU1) K19046 casB; CRISPR system Cascade subunit CasB
D BN49_1001 unnamed protein product; highly similar to CRISPR-associated protein, Cse4 family from Escherichia coli O55:H7 strain CB9615 - EPEC (tr|D3QPV5) K19124 casC; CRISPR system Cascade subunit CasC
D BN49_1002 unnamed protein product; highly similar to CRISPR-associated protein from Escherichia coli O44:H18 strain 042 - EAEC (tr|D3GRT9) K19125 casD; CRISPR system Cascade subunit CasD
D BN49_1003 unnamed protein product; highly similar to N-terminal of putative CRISPR-associated protein, Cse3 family from Escherichia coli O55:H7 strain CB9615 - EPEC (tr|D3QPV3) K19126 casE; CRISPR system Cascade subunit CasE
C Subtype I-F factors
C Subtype I-U factors
B Type II CRISPR-Cas system
C Type II signiture cas proteins
C Subtype II-A factors
C Subtype II-B factors
B Type III CRISPR-Cas system
C Type III signiture cas proteins
C Subtype III-A factors
C Subtype III-B factors
C Subtype III-U factors
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ARestriction and modification system (R-M system)
B Type I R-M system
B Type II R-M system
C Restriction endonucleases
C DNA methyltransferases
D BN49_2606 unnamed protein product; weakly similar to C-terminal region of probable DNA methyltransferase from Escherichia coli O111:H-strain 11128 - EHEC (tr|C8UR62) K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D BN49_1940 unnamed protein product; highly similar to putative site-specific DNA-methyltransferase adenine-specific from Escherichia coli O81 (tr|B7MYU7) K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D BN49_0359 unnamed protein product; highly similar to DNA adenine methylase from from Escherichia coli strain K12 (sp|P0AEE8) K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D BN49_3534 dcm; highly similar to cytosine-specific methyltransferase from Escherichia coli strain UTI89 - UPEC (tr|Q1RAH9) K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
B Type III R-M system
B Type IV R-M system
C BN49_2617 unnamed protein product; highly similar to putative prophage endonuclease from Escherichia coli O44:H18 strain 042 - EAEC (tr|D3GYF4) K07451 mcrA; 5-methylcytosine-specific restriction enzyme A [EC:3.1.21.-]
C BN49_2260 unnamed protein product; similar to putative phage endonuclease from Escherichia coli O44:H18 strain 042 - EAEC (tr|D3GYY4) K07451 mcrA; 5-methylcytosine-specific restriction enzyme A [EC:3.1.21.-]
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AToxin-antitoxin system (TA system)
B Type I TA system
C Hok-Sok
D BN49_1031 unnamed protein product; highly similar to C-terminal region of small toxic membrane polypeptide from Escherichia coli O55:H7 strain CB9615 - EPEC (tr|D3QPV9) K18922 hokE; protein HokE
C SymE-SymR
D BN49_1074 unnamed protein product; similar to putative exported protein from Citrobacter rodentium (tr|D2TLE1) K19048 symE; toxic protein SymE
C Ldr-Rdl
C TisB-IstR
C Ibs-Sib
C ShoB-OhsC
C RalR-RalA
B Type II TA system
C MazF-MazE
C ChpB-ChpS
C YhaV-PrlF
C RelE/StbE-RelB/StbD
D BN49_pI0106 unnamed protein product; highly similar to uncharacterized RelE-like protein from Escherichia coli (sp|Q60228) K06218 relE; mRNA interferase RelE/StbE
D BN49_4793 relE; similar to putative RelE protein from Escherichia coli B088 (tr|D6I4C4) K06218 relE; mRNA interferase RelE/StbE
D BN49_4794 relB; highly similar to putative RelB protein from Salmonella typhi (tr|Q8XES7) K18918 relB; RHH-type transcriptional regulator, rel operon repressor / antitoxin RelB
D BN49_pI0107 unnamed protein product; highly similar to toxin-antitoxin system, antitoxin component, PHD family from Escherichia coli MS 185-1 (tr|D8C8X9) K18923 stbD; antitoxin StbD
D BN49_pII0007 unnamed protein product; similar to toxin-antitoxin system, antitoxin component, PHD family from Escherichia coli H299 (tr|F4W3J0) K18923 stbD; antitoxin StbD
C YafQ-dinJ
C YoeB-YefM
C HipA-HipB
D BN49_2775 hipA; similar to protein HipA from Escherichia coli strain K12 (sp|P23874) K07154 hipA; serine/threonine-protein kinase HipA [EC:2.7.11.1]
D BN49_2774 hipB; similar to HTH-type transcriptional regulator HipB from Escherichia coli strain K12 (sp|P23873) K15773 hipB; HTH-type transcriptional regulator / antitoxin HipB
C HicA-HicB
C YafO-YafN
C Hha-TomB
D BN49_pI0083 unnamed protein product; highly similar to putative hemolysin expression modulating protein from Providencia rettgeri DSM 1131 (tr|D4C185) K05839 hha; haemolysin expression modulating protein
D BN49_1416 hha; highly similar to hemolysin expression modulating protein from Escherichia coli strain UTI89 - UPEC (tr|Q1RF76) K05839 hha; haemolysin expression modulating protein
D BN49_1417 ybaJ; highly similar to putative uncharacterized protein YbaJ from Escherichia coli strain UTI89 - UPEC (tr|Q1RF75) K19162 tomB; hha toxicity modulator TomB
C PspC-PspB
D BN49_2439 unnamed protein product; highly similar to phage shock protein C from Escherichia coli O1:K1 - APEC (tr|A1AAR9) K03973 pspC; phage shock protein C
D BN49_2438 unnamed protein product; highly similar to phage shock protein B from Escherichia coli O55:H7 strain CB9615 - EPEC (tr|D3QRT2|) K03970 pspB; phage shock protein B
C CcdB-CcdA
D BN49_2963 ccdB; similar to putative CcdB protein from Enterobacter cloacae subsp. cloacae (tr|D6DQX7) K19163 ccdB; toxin CcdB
C ParE-ParD
C Doc-Phd
D BN49_0302 unnamed protein product; similar to death on curing protein from Enterobacteria phage P1 (sp|Q06259) K07341 doc; death on curing protein
D BN49_0301 yhhV; highly similar to prevent-host-death family protein from Klebsiella variicola strain At-22 (tr|D3RD82) and to uncharacterized protein YhhV from Salmonella typhimurium (sp|P40819) K19165 phd; antitoxin Phd
C HigB-HigA
D BN49_pI0025 unnamed protein product; similar to putative HTH-type transcriptional regulator YgjM from Escherichia coli O81 strain ED1a (tr|B7MYL6) K18831 higA; HTH-type transcriptional regulator / antitoxin HigA
C MqsR-MqsA
C VapC-VapB
D BN49_pI0089 vagD; highly similar to virulence-associated protein VagD from Escherichia coli (tr|B1VCL4) K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-]
D BN49_pI0090 vagC; highly similar to virulence-associated protein VagC from Salmonella dublin (sp|Q05459) K18829 mvpT; antitoxin VapB
C PezT-PezA
C YobL-YobK
C YokI-YokJ
C YqcG-YqcF
C YxiD-YxxD
C FitB-FitA
C BC_0920-BC_0921
C Type II TA system related factors
D BN49_4779 yjgK; highly similar to putative uncharacterized protein YjgK from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (tr|A6THH5) K19334 tabA; biofilm protein TabA
D BN49_1884 unnamed protein product; highly similar to putative uncharacterized protein from Klebsiella pneumoniae NTUH-K2044 (tr|C4X5W7) K13650 mcbA; MqsR-controlled colanic acid and biofilm protein A
D BN49_2159 yceP; highly similar to putative uncharacterized protein YceP from Escherichia coli strain UTI89 - UPEC (tr|Q1RD97) K12148 bssS; biofilm regulator BssS
D BN49_1920 bssR; similar to biofilm regulator BssR from Salmonella enterica (tr|B5PFM9) K19688 bssR; biofilm regulator BssR
D BN49_2197 unnamed protein product; highly similar to putative uncharacterized protein from Escherichia coli O150:H5 strain SE15 (tr|D2NHC8) K12151 bhsA; multiple stress resistance protein BhsA
D BN49_4241 unnamed protein product; highly similar to cell division protein FtsZ from Escherichia coli strain UTI89 - UPEC (tr|Q1RGA0) K03531 ftsZ; cell division protein FtsZ
D BN49_0461 mreB; highly similar to putative rod shape-determining protein MreB from Citrobacter sp. (tr|C1MA49) K03569 mreB; rod shape-determining protein MreB and related proteins
D BN49_0671 parC; highly similar to DNA topoisomerase 4 subunit A from Shigella flexneri (sp|P0AFI4) K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]
D BN49_0664 parE; highly similar to DNA topoisomerase 4 subunit B from Salmonella typhimurium (sp|P0A2I5) K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]
D BN49_3964 gltX; highly similar to glutamyl-tRNA synthetase from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TC43) K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
B Type III TA system
C AbiQ system
B Type IV TA system
C YeeV-YeeU
C CptA-CptB
D BN49_0764 unnamed protein product; highly similar to putative uncharacterized protein from Escherichia coli O150:H5 strain SE15 (tr|D2NM57) K19168 cptA; toxin CptA
D BN49_0763 ygfY; highly similar to putative uncharacterized protein YgfY from Escherichia coli strain UTI89 - UPEC (tr|Q1R7D4) K09159 cptB; antitoxin CptB
B Type V TA system
C GhoT-GhoS
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ADNA phosphothiolation system
B Sulfur modification proteins
C BN49_4070 iscS; highly similar to cysteine desulfurase from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TCF1) K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
B DNA phosphorothioation-dependent restriction proteins
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: October 9, 2020