+E Ribosome biogenesis KO
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Ribosome Biogenesis - Klebsiella pneumoniae Kp52.145
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AEukaryotic type
B Sno RNPs
C Box C/D snoRNPs
C Box H/ACA snoRNPs
B 90S particles
C U3 small nucleolar RNA-associated proteins
C Helicases
C GTPase
C RNase
D BN49_4101 rnc; highly similar to ribonuclease 3 from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TCI1) K03685 rnc; ribonuclease III [EC:3.1.26.3]
C Kinase
C Other 90S particles
B Pre-40S particles
C Kinases
C Export and cytoplasmic maturation factors
C Other pre-40S particles
B Pre-60S particles
C Helicases
C GTPases
C RNases
D BN49_4871 orn; highly similar to oligoribonuclease from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TH79) K13288 orn; oligoribonuclease [EC:3.1.-.-]
D RNase MRP
C Kinases
C Export and cytoplasmic maturation factors
C 5-FMC complex
C Ribosome quality control proteins
C Other pre-60S particles
B Other ribosome biogenesis factors
C BN49_4100 era; highly similar to GTP-binding protein Era homolog from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TCI0) K03595 era; GTPase
C BN49_0526 obg; highly similar to GTPase Obg from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TEK2) K03979 obgE; GTPase [EC:3.6.5.-]
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AProkaryotic type
B Sno RNPs
C Box C/D snoRNPs
C Box H/ACA snoRNPs
B rRNA transcription factors
C BN49_3568 unnamed protein product; highly similar to putative transcriptional regulator from Escherichia coli (tr|C0J1H7) K06204 dksA; DnaK suppressor protein
C BN49_4195 dksA; highly similar to DnaK suppressor protein from Escherichia coli strain UTI89 - UPEC (tr|Q1RG45) K06204 dksA; DnaK suppressor protein
C BN49_0540 nusA; highly similar to transcription elongation protein from Escherichia coli O44:H18 strain 042 - EAEC (tr|D3GXR0) K02600 nusA; transcription termination/antitermination protein NusA
C BN49_1342 nusB; highly similar to N utilization substance protein B homolog from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6T5E9) K03625 nusB; transcription antitermination protein NusB
C BN49_4480 nusG; highly similar to transcription antitermination protein NusG from Salmonella typhimurium (sp|P0AA02) K02601 nusG; transcription termination/antitermination protein NusG
B rRNA modification factors
C 16S rRNA modification factors
D BN49_3833 unnamed protein product; highly similar to pseudouridine synthase from Escherichia coli O6:K15:H31 strain 536 - UPEC (tr|Q0TFQ6) K06183 rsuA; 16S rRNA pseudouridine516 synthase [EC:5.4.99.19]
D BN49_4292 rsmA; highly similar to ribosomal RNA small subunit methyltransferase A from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6T4I7) K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]
D BN49_0429 rsmB; highly similar to ribosomal RNA small subunit methyltransferase B from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TEU2) K03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176]
D BN49_4368 rsmC; highly similar to ribosomal RNA small subunit methyltransferase C from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6THY6) K00564 rsmC; 16S rRNA (guanine1207-N2)-methyltransferase [EC:2.1.1.172]
D BN49_0286 unnamed protein product; highly similar to predicted methyltransferase from Escherichia coli O111:H-strain 11128 - EHEC (tr|C8UHU5) K08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171]
D BN49_0723 unnamed protein product; highly similar to putative uncharacterized protein ECs3822 from Escherichia coli O157:H7 (tr|Q8XCW3) K09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193]
D BN49_3456 rsmF; highly similar to ribosomal RNA small subunit methyltransferase F from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TB06) K11392 rsmF; 16S rRNA (cytosine1407-C5)-methyltransferase [EC:2.1.1.178]
D BN49_5062 rsmG; highly similar to ribosomal RNA small subunit methyltransferase G from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TG44) K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]
D BN49_4254 rsmH; highly similar to ribosomal RNA small subunit methyltransferase H from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6T4M5) K03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199]
D BN49_0563 rsmI; highly similar to ribosomal RNA small subunit methyltransferase I from Escherichia coli 3030-1 (tr|G1ZP72) K07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198]
D BN49_0255 unnamed protein product; highly similar to UPF0341 protein KPN78578_38250 from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TFB5) K15984 rsmJ; 16S rRNA (guanine1516-N2)-methyltransferase [EC:2.1.1.242]
C 23S rRNA modification factors
D BN49_3443 rlmA; highly similar to ribosomal RNA large subunit methyltransferase A from Escherichia coli strain K12 (sp|P36999) K00563 rlmA1; 23S rRNA (guanine745-N1)-methyltransferase [EC:2.1.1.187]
D BN49_4853 rlmB; highly similar to hypothetical tRNA-rRNA methyltransferase YjfH from Escherichia coli O6:K15:H31 (tr|Q0T9L3) K03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185]
D BN49_0530 rlmE; highly similar to ribosomal RNA large subunit methyltransferase E from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TEJ8) K02427 rlmE; 23S rRNA (uridine2552-2'-O)-methyltransferase [EC:2.1.1.166]
D BN49_1886 rlmF; highly similar to ribosomal RNA large subunit methyltransferase F from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6T6Q1) K06970 rlmF; 23S rRNA (adenine1618-N6)-methyltransferase [EC:2.1.1.181]
D BN49_0596 rlmG; highly similar to ribosomal RNA large subunit methyltransferase G from Klebsiella pneumoniae strain 342 (sp|B5XTX7) K11391 rlmG; 23S rRNA (guanine1835-N2)-methyltransferase [EC:2.1.1.174]
D BN49_1728 rlmH; highly similar to ribosomal RNA large subunit methyltransferase H from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6T697) K00783 rlmH; 23S rRNA (pseudouridine1915-N3)-methyltransferase [EC:2.1.1.177]
D BN49_2090 rlmI; highly similar to ribosomal RNA large subunit methyltransferase I from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6T766) K06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191]
D BN49_0252 yhiR; highly similar to putative DNA (exogenous) processing protein from Escherichia coli O7:K1 strain IAI39 - ExPEC (tr|B7NNC1) K07115 rlmJ; 23S rRNA (adenine2030-N6)-methyltransferase [EC:2.1.1.266]
D BN49_2072 rlmL; highly similar to ribosomal RNA large subunit methyltransferase L from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6T742) K12297 rlmKL; 23S rRNA (guanine2069-N7)-methyltransferase / 23S rRNA (guanine2445-N2)-methyltransferase [EC:2.1.1.264 2.1.1.173]
D BN49_0955 rlmM; highly similar to ribosomal RNA large subunit methyltransferase M from Klebsiella pneumoniae strain 342 (sp|B5XUY0) K06968 rlmM; 23S rRNA (cytidine2498-2'-O)-methyltransferase [EC:2.1.1.186]
D BN49_4056 rlmN; highly similar to ribosomal RNA large subunit methyltransferase N from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TCD6) K06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192]
D BN49_0987 rlmD; highly similar to 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TD57) K03215 rumA; 23S rRNA (uracil1939-C5)-methyltransferase [EC:2.1.1.190]
D BN49_1986 rlmC; highly similar to 23S rRNA (uracil-5-)-methyltransferase from Citrobacter koseri (sp|A8AIQ7) K03212 rumB; 23S rRNA (uracil747-C5)-methyltransferase [EC:2.1.1.189]
D BN49_3379 unnamed protein product; highly similar to pseudouridine synthase from Yersinia bercovieri (tr|C4RYK9) K06177 rluA; tRNA pseudouridine32 synthase / 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]
D BN49_4283 rluA; highly similar to ribosomal large subunit pseudouridine synthase A from Shigella flexneri (sp|P0AA38) K06177 rluA; tRNA pseudouridine32 synthase / 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]
D BN49_2403 rluB; highly similar to ribosomal large subunit pseudouridine synthase B from Shigella flexneri (sp|P59815) K06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22]
D BN49_2171 rluC; highly similar to ribosomal large subunit pseudouridine synthase C from Salmonella typhimurium (sp|Q8ZQ16) K06179 rluC; 23S rRNA pseudouridine955/2504/2580 synthase [EC:5.4.99.24]
D BN49_1181 rluD; highly similar to ribosomal large subunit pseudouridine synthase D from Salmonella typhimurium (sp|P65836) K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23]
D BN49_2232 rluE; highly similar to ribosomal large subunit pseudouridine synthase E from Escherichia coli O6 (sp|Q8FIB6) K06181 rluE; 23S rRNA pseudouridine2457 synthase [EC:5.4.99.20]
D BN49_5024 rluF; highly similar to ribosomal large subunit pseudouridine synthase F from Shigella flexneri (sp|Q83IR6) K06182 rluF; 23S rRNA pseudouridine2604 synthase [EC:5.4.99.21]
D BN49_4113 yfiF; highly similar to hypothetical tRNA-rRNA methyltransferase YfiF from Escherichia coli O6:K15:H31 strain 536 - UPEC (tr|Q0TEQ7) K03214 yfiF; RNA methyltransferase, TrmH family [EC:2.1.1.-]
B ribosomal protein modification factors
C BN49_4366 rimI; highly similar to ribosomal-protein-alanine acetyltransferase from Escherichia coli strain ATCC 33849 - DSM 4235 - NCIB 12045 - K12 - DH1 (tr|C9QSU8) K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266]
C BN49_2164 rimJ; highly similar to ribosomal-protein-alanine acetyltransferase from Escherichia coli O55:H7 strain CB9615 - EPEC (tr|D3QQ61) K03790 rimJ; [ribosomal protein S5]-alanine N-acetyltransferase [EC:2.3.1.267]
C BN49_3912 unnamed protein product; similar to putative GCN5-related N-acetyltransferase from Enterobacter cloacae (tr|D5C691) K03790 rimJ; [ribosomal protein S5]-alanine N-acetyltransferase [EC:2.3.1.267]
C BN49_1979 rimK; highly similar to ribosomal protein S6 modification protein from Klebsiella pneumoniae strain 342 (sp|B5XYN4) K05844 rimK; ribosomal protein S6--L-glutamate ligase [EC:6.3.2.-]
C BN49_3039 rimL; similar to ribosomal-protein-serine acetyltransferase from Escherichia coli strain K12 (sp|P13857) K03817 rimL; ribosomal-protein-serine acetyltransferase [EC:2.3.1.-]
C BN49_1167 rimM; highly similar to ribosome maturation factor RimM from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TCL6) K02860 rimM; 16S rRNA processing protein RimM
C BN49_1918 rimO; highly similar to ribosomal protein S12 methylthiotransferase RimO from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6T6T1) K14441 rimO; ribosomal protein S12 methylthiotransferase [EC:2.8.4.4]
C BN49_2032 unnamed protein product; highly similar to putative uncharacterized protein from Escherichia coli E22 (tr|B3I7Y4) K09136 ycaO; ribosomal protein S12 methylthiotransferase accessory factor
C BN49_0452 prmA; highly similar to ribosomal protein L11 methyltransferase from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TES6) K02687 prmA; ribosomal protein L11 methyltransferase [EC:2.1.1.-]
C BN49_3937 yfcB; highly similar to uncharacterized adenine-specific methylase YfcB from Salmonella typhimurium (sp|P0A293) K07320 prmB; ribosomal protein L3 glutamine methyltransferase [EC:2.1.1.298]
C BN49_2223 unnamed protein product; highly similar to putative uncharacterized protein ECs1573 from Escherichia coli O157:H7 (tr|Q8X776) K18850 ycfD; 50S ribosomal protein L16 3-hydroxylase [EC:1.14.11.47]
C BN49_4702 unnamed protein product; highly similar to Cupin family protein from Klebsiella pneumoniae strain 342 (tr|B5Y2J1) K18850 ycfD; 50S ribosomal protein L16 3-hydroxylase [EC:1.14.11.47]
B rRNA processing factors
C BN49_4101 rnc; highly similar to ribonuclease 3 from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TCI1) K03685 rnc; ribonuclease III [EC:3.1.26.3]
C BN49_2170 rne; highly similar to ribonuclease E from Escherichia coli O157:H7 str. TW14588 (tr|B6ZZX1) K08300 rne; ribonuclease E [EC:3.1.26.12]
C BN49_0465 rng; highly similar to ribonuclease G from Escherichia coli strain UTI89 - UPEC (tr|Q1R693) K08301 rng; ribonuclease G [EC:3.1.26.-]
C BN49_0720 ruvX; highly similar to putative holliday junction resolvase from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TDV8) K07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-]
B rRNA helicases
C BN49_0547 deaD; highly similar to cold-shock DEAD box protein A from Klebsiella pneumoniae (sp|P33906) K05592 deaD; ATP-dependent RNA helicase DeaD [EC:3.6.4.13]
C BN49_2501 dbpA; highly similar to ATP-independent RNA helicase DbpA from Escherichia coli strain K12 (sp|P21693) K05591 dbpA; ATP-dependent RNA helicase DbpA [EC:3.6.4.13]
C BN49_4110 srmB; highly similar to ATP-dependent RNA helicase SrmB from Escherichia coli O6 (tr|Q8FF13) K05590 srmB; ATP-dependent RNA helicase SrmB [EC:3.6.4.13]
B GTPases
C BN49_4100 era; highly similar to GTP-binding protein Era homolog from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TCI0) K03595 era; GTPase
C BN49_4872 rsgA; highly similar to putative ribosome biogenesis GTPase RsgA from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TH78) K06949 rsgA; ribosome biogenesis GTPase / thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]
C BN49_4050 engA; highly similar to GTP-binding protein EngA from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TCD0) K03977 engA; GTPase
C BN49_0526 obg; highly similar to GTPase Obg from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TEK2) K03979 obgE; GTPase [EC:3.6.5.-]
C BN49_4861 hflX; highly similar to predicted HflX protein, putative GTP-binding protein from Salmonella enteritidis PT4 (tr|B5R0P0) K03665 hflX; GTPase
B Other maturation factors
C BN49_0435 rimN; highly similar to putative ribosome maturation factor RimN from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TET6) K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
C BN49_0109 spoT; highly similar to bifunctional (P)ppGpp synthetase II-guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase from Salmonella enterica (tr|E8H0E6) K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]
C BN49_0542 rbfA; highly similar to ribosome-binding factor A from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TEI6) K02834 rbfA; ribosome-binding factor A
C BN49_0539 rimP; highly similar to ribosome maturation factor RimP from Enterobacter sp. strain 638 (sp|A4WEY5) K09748 rimP; ribosome maturation factor RimP
C BN49_1457 ybcJ; highly similar to putative uncharacterized protein ECs0590 from Escherichia coli O157:H7 (tr|Q8XCT7) K14761 ybcJ; ribosome-associated protein
C BN49_1729 ybeB; highly similar to putative uncharacterized protein YbeB from Escherichia coli strain UTI89 - UPEC (tr|Q1RES5) K09710 ybeB; ribosome-associated protein
C BN49_1744 unnamed protein product; highly similar to putative metalloprotease KPN78578_06730 from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6T6B3) K07042 ybeY; probable rRNA maturation factor
C BN49_0529 yhbY; highly similar to hypothetical RNA binding protein from Escherichia coli O6:K15:H31 strain 536 - UPEC (tr|Q0TCT0) K07574 yhbY; RNA-binding protein
C BN49_0165 yibL; highly similar to putative uncharacterized protein YibL from Escherichia coli O55:H7 strain CB9615 - EPEC (tr|D3QV27) K14762 yibL; ribosome-associated protein
C BN49_4807 yjgA; highly similar to putative uncharacterized protein YjgA from Escherichia coli strain B - REL606 (tr|C6UL12) K09889 yjgA; ribosome-associated protein
C BN49_0507 unnamed protein product; highly similar to probable sigma(54) modulation protein from Klebsiella oxytoca (sp|P17161) K05808 yhbH; putative sigma-54 modulation protein
C BN49_1179 yhbH; highly similar to putative YhbH sigma 54 modulator from Escherichia coli strain UTI89 - UPEC (tr|Q1R8C7) K05809 raiA; ribosome-associated inhibitor A
C BN49_2944 sra; similar to stationary-phase-induced ribosome-associated protein from Salmonella typhimurium (sp|Q7CQJ0) K02972 sra; stationary-phase-induced ribosome-associated protein
C BN49_3351 engD; highly similar to GTP-dependent nucleic acid-binding protein EngD from Escherichia coli O55:H7 strain CB9615 - EPEC (tr|D3QQX6) K06942 ychF; ribosome-binding ATPase
C BN49_2173 yceD; highly similar to putative uncharacterized protein YceD from Escherichia coli strain UTI89 - UPEC (tr|Q1RD69) K07040 yceD; DUF177 domain-containing protein
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ARelated small nucleolar RNAs
B Box C/D snoRNAs
C SnoRNAs involved in processing reactions
C SnoRNAs act as guides for 2'-O-ribose methylation
B Box H/ACA snoRNAs
C SnoRNAs involved in processing reactions
C SnoRNAs act as guides for pseudouridynation
B Other snoRNA
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: November 4, 2022