+F Chromosome and associated proteins KO
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Chromosome and Associated Proteins - Klebsiella pneumoniae Kp52.145
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AEukaryotic type
B Sister chromatid cohesion proteins
C Cohesin complex
C Adherin complex
C CTF18-RFC complex
C Fork protection complex
C Other sister chromatid cohesion factors
B Meiosis-specific proteins
C Cohesin complex and associated proteins
C Synaptonemal complex
C DSB formation-related proteins
C Others
B Nucleosome assembly factors
C Histones
C Histone chaperones
D Nucleoplasmins
D NAPs (Nucleosome assembly proteins)
D CAF-1
D FACT complex
D Other Histone chaperones and regulators
C HMG (high mobility group) proteins
B Histone modification proteins
C HATs (histone acetyltransferases)
C HAT complexes
D PCAF complex
D STAGA complex
D TFTC complex
D TIP60 complex
D HBO1 complex
D MOZ/MORF complex
D SAGA complex
D SLIK complex
D ADA-HAT complex
D HAT-A2 complex
D ATAC complex
D HATB complex
D NSL complex
D MSL complex
D NuA3 complex
D NuA4 complex
D SAS complex
C HDACs (histone deacetylases)
D Class I HDACs
D Class II HDACs
D SIRTs (sirtuins, class III HDACs)
D Class IV HDACs
C HDAC complexes
D Sin3A-HDAC complex
D BRAF-HDAC complex
D REST complex
D Other HDAC associated proteins
C HMTs (histone methyltransferases)
D HKMTs (histone lysine methyltransferases)
D PRMTs (protein arginine metyltransferases)
C HMT complexes
D COMPASS/SET1 complex
D COMPASS/SET1 complex (yeast)
D MLL-HCF complex
D MLL3/MLL4 complex
D Dot1-containing complex
C Histone demethylases
C Polycomb group proteins
D PRC1 (polycomb repressive complex 1)
D PRC2-EZH1 complex
D PRC2-EZH2 complex
D AUTS2-polycomb complex
D Other polycomb group proteins
C Sir proteins
C Other histone modification proteins
B Chromosome condensation proteins
C Condensin I
C Condensin II
C Other regulators of chromosome condensation
B Centromeric chromatin formation proteins
C Kinetochore proteins
D Centromere proteins
D CPC (chromosomal passenger complex)
D KMN network proteins
E MIS12 complex
E NDC80 complex
D Mis6 complex
D COMA complex
D NMS complex
E NDC80 complex
E MIND kinetochore complex
D MIS16-MIS18 complex
D DASH complex
D CBF3 complex
D Others
C SAC (spindle assembly checkpoint) factors
D Core SAC proteins
D Motor proteins
E RZZ complex
E Dynein complex
D Protein kinases
D Others
C Other centromeric chromatin formation proteins
D Shugoshin
D PP2A (protein phosphatase 2A)
B Heterochromatin formation proteins
C HP1 (heterochromatin protein 1)
C MBPs (metylated DNA binding proteins)
C Other heterochromatin formation proteins
D BN49_3534 dcm; highly similar to cytosine-specific methyltransferase from Escherichia coli strain UTI89 - UPEC (tr|Q1RAH9) K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
B Gene silencing
C RISC (RNA-induced silencing complex)
C piRNA pathway
C RNA interference (RNAi) pathway
D RITS (RNA-induced transcriptional silencing) complex
D RDRC (RNA-directed RNA polymerase complex)
D Other RNAi proteins
C microRNA pathway
D Microprocessor complex
E BN49_4101 rnc; highly similar to ribonuclease 3 from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TCI1) K03685 rnc; ribonuclease III [EC:3.1.26.3]
D RISC loading complex
D Other miRNA pathway proteins
C Transposable elements
B Centrosome formation proteins
C Centriole proteins
C Pericentriolar materials (PCM)
D Centriolar satellite
D Other PCM proteins
C Cyclins
C Kinases and associated factors
D Kinase anchoring protein
C Microtubules and associated factors
D gamma-tubulin ring complex
D Other tubulins
D Dynactin complex
D BRISC complex
D Microtubule-associated proteins
C Augmin complex
C Centrosome duplication proteins
D Centriole replication proteins
D Regulators of centriole replication
D Other centrosome duplication proteins
C Nde1-Su48 complex
C LINC complex
C 3M complex
C Other centriole associated proteins
C Spindle formation proteins
B Sister chromatid separation proteins
C Securin and associated proteins
C Separase
C APC/C complex
C Aurora kinases
D Regulators of Aurora kinases
C TACC proteins
C Polo kinases
C Early mitotic inhibitors
B Chromatin remodeling factors
C BAF complex
C PBAF complex
C GBAF(ncBAF) complex
C CHRAC complex
C RSF complex
C WICH complex
C B-WICH complex
C NORC complex
C BRF complex
C NuRD complex
C NuRF complex
C NuRF complex (fruit fly)
C CERF complex
C SRCAP complex
C INO80 complex
C INO80 complex (yeast)
C RSC complex
C SWI/SNF complex
C SWR1 complex
C ASTRA complex
C Other chromatin remodeling factors
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AProkaryotic type
B Nucleoid associated proteins
C HNS (histone-like nucleoid structuring protein)
D BN49_pII0094 unnamed protein product; similar to putative histone family protein nucleoid-structuring protein H-NS from Pantoea sp (tr|C8Q7K8) K03746 hns; DNA-binding protein H-NS
D BN49_3310 hns; highly similar to Hns transcriptional dual regulator from Escherichia coli strain UTI89 - UPEC (tr|Q1RCK0) K03746 hns; DNA-binding protein H-NS
D BN49_1125 unnamed protein product; highly similar to DNA-binding protein H-NS from Escherichia coli O55:H7 strain CB9615 - EPEC (tr|D3QPM0) K11685 stpA; DNA-binding protein StpA
C HU (heat unstable protein)
D BN49_1376 hupB; highly similar to DNA-binding protein HU-beta, NS1 (HU-1) from Escherichia coli strain UTI89 - UPEC (tr|Q1RF95) K03530 hupB; DNA-binding protein HU-beta
C IHF (integration host factor)
D BN49_3282 unnamed protein product; highly similar to integration host factor subunit alpha from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TAI1) K04764 ihfA; integration host factor subunit alpha
D BN49_2038 ihfB; highly similar to integration host factor subunit beta from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6T704) K05788 ihfB; integration host factor subunit beta
C Other nucleoid associated proteins
D BN49_4921 cbpA; highly similar to curved DNA-binding protein from Citrobacter koseri (sp|A8AI78) K05516 cbpA; curved DNA-binding protein
D BN49_4922 cbpM; highly similar to putative chaperone-modulator protein CbpM from Escherichia coli E22 (tr|B3I7K0) K18997 cbpM; chaperone modulatory protein CbpM
D BN49_4345 rob; highly similar to right origin-binding protein from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (tr|A6TI10) K05804 rob; AraC family transcriptional regulator, mar-sox-rob regulon activator
D BN49_1154 unnamed protein product; highly similar to putative transcriptional regulator, AraC family from Enterobacter cloacae (tr|D6DNF1) K05804 rob; AraC family transcriptional regulator, mar-sox-rob regulon activator
D BN49_0001 dnaA; highly similar to chromosomal replication initiator protein DnaA from Klebsiella pneumoniae strain 342 (sp|B5XT51) K02313 dnaA; chromosomal replication initiator protein
D BN49_0560 diaD; highly similar to DnaA initiator-associating protein DiaA from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TEG8) K12961 diaA; DnaA initiator-associating protein
D BN49_2089 hspQ; highly similar to heat shock protein HspQ from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6T765) K11940 hspQ; heat shock protein HspQ
D BN49_1891 dps; highly similar to DNA protection during starvation protein from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6T6Q6) K04047 dps; starvation-inducible DNA-binding protein
D BN49_0450 fis; highly similar to global DNA-binding transcriptional dual regulator Fis from Escherichia coli O111:H-strain 11128 - EHEC (tr|C8UGL9) K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
D BN49_4862 hfq; highly similar to host factor-I protein from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TH87) K03666 hfq; host factor-I protein
D BN49_0741 iciA; highly similar to chromosome initiation inhibitor from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TDS6) K05596 iciA; LysR family transcriptional regulator, chromosome initiation inhibitor
D BN49_3317 unnamed protein product; highly similar to putative transcriptional regulator, AsnC family from Enterobacter cancerogenus (tr|D2ZDA6) K03719 lrp; Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein
D BN49_2020 lrp; highly similar to leucine-responsive regulatory protein from Salmonella typhimurium (sp|P0A2S0) K03719 lrp; Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein
D BN49_2057 unnamed protein product; highly similar to putative leucine response regulator from Salmonella typhimurium (tr|Q8ZQB2) K03719 lrp; Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein
D BN49_3840 ndpA; highly similar to nucleoid-associated protein NdpA from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TBS0) K06899 ndpA; nucleoid-associated protein
B Chromosome partitioning proteins
C MukBEF complex
D BN49_2050 mukB; highly similar to chromosome partition protein MukB from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6T716) K03632 mukB; chromosome partition protein MukB
D BN49_2049 mukE; highly similar to chromosome partition protein MukE from Escherichia coli O157:H7 strain EC4115 - EHEC (tr|B5YT57) K03804 mukE; chromosome partition protein MukE
D BN49_2048 mukF; highly similar to chromosome partition protein MukF from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6T714) K03633 mukF; chromosome partition protein MukF
C Condensin-like complex
C Divisome proteins
D BN49_4242 ftsA; highly similar to ATP-binding cell division protein, septation process, complexes with FtsZ, associated with junctions of inner and outer membranes from Escherichia coli strain UTI89 - UPEC (tr|Q1RGA1) K03590 ftsA; cell division protein FtsA
D BN49_1016 ftsB; highly similar to cell division protein FtsB homolog from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TD40) K05589 ftsB; cell division protein FtsB
D BN49_0288 ftsE; highly similar to cell division ATP-binding membrane protein FtsE from Escherichia coli strain UTI89 - UPEC (tr|Q1R5F7) K09812 ftsE; cell division transport system ATP-binding protein
D BN49_3444 ftsI; highly similar to penicillin-binding protein-3 from Salmonella choleraesuis (tr|Q57NH5) K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]
D BN49_4252 pbp3; highly similar to peptidoglycan synthetase (penicillin-binding protein 3) from Escherichia coli O44:H18 (tr|D3H465) K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]
D BN49_2021 ftsK; highly similar to DNA translocase FtsK from Shigella flexneri (sp|Q83S00) K03466 ftsK; DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family
D BN49_4253 ftsL; highly similar to putative cell division protein FtsL from Escherichia coli O6:K15:H31 (tr|Q0TLQ6) K03586 ftsL; cell division protein FtsL
D BN49_4628 ftsN; highly similar to essential cell division protein from Escherichia coli O157:H7 (tr|Q8X789) K03591 ftsN; cell division protein FtsN
D BN49_4243 ftsQ; highly similar to membrane anchored protein involved in growth of wall at septum from Escherichia coli O7:K1 strain IAI39 - ExPEC (tr|B7NHJ9) K03589 ftsQ; cell division protein FtsQ
D BN49_4247 ftsW; highly similar to cell division protein FtsW from Escherichia coli strain UTI89 - UPEC (tr|Q1RGA6) K03588 ftsW; cell division protein FtsW
D BN49_0289 ftsX; highly similar to cell division membrane protein from Escherichia coli strain UTI89 - UPEC (tr|Q1R5F8) K09811 ftsX; cell division transport system permease protein
D BN49_4241 unnamed protein product; highly similar to cell division protein FtsZ from Escherichia coli strain UTI89 - UPEC (tr|Q1RGA0) K03531 ftsZ; cell division protein FtsZ
D BN49_3969 zipA; highly similar to cell division protein ZipA homolog from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TC48) K03528 zipA; cell division protein ZipA
D BN49_0745 zapA; highly similar to cell division protein ZapA from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TDS2) K09888 zapA; cell division protein ZapA
D BN49_0098 zapB; highly similar to cell division protein ZapB from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TFR0) K09892 zapB; cell division protein ZapB
D BN49_2070 unnamed protein product; highly similar to putative uncharacterized protein from Escherichia coli (tr|C3TFV2) K18657 zapC; cell division protein ZapC
D BN49_4235 unnamed protein product; highly similar to UPF0289 protein KPN78578_01040 from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6T4P4) K18778 zapD; cell division protein ZapD
D BN49_2918 unnamed protein product; weakly similar to putative ATPase, AFG1 family from Pseudomonas aeruginosa (tr|A6VBS5) K06916 zapE; cell division protein ZapE
D BN49_0489 unnamed protein product; highly similar to putative ATPase, AFG1 family from Escherichia coli strain SMS-3-5 - SECEC (tr|B1LGJ8) K06916 zapE; cell division protein ZapE
D BN49_4834 oapA; similar to putative opacity-associated protein A from Escherichia coli (tr|C6ECD8). It presents the OapA N-terminal and LysM domains according to Pfam. K07269 ytfB; cell division protein YtfB
D BN49_0883 amiC; highly similar to N-acetylmuramoyl-L-alanine amidase AmiC from Escherichia coli strain UTI89 - UPEC (tr|Q1R7J7) K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]
D BN49_3989 amiA; highly similar to N-acetylmuramoyl-l-alanine amidase I from Escherichia coli O150:H5 strain SE15 (tr|D2NL12) K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]
D BN49_4865 amiB; highly similar to putative N-acetylmuramoyl-L-alanine amidase AmiB from Escherichia coli strain UTI89 - UPEC (tr|Q1R391) K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]
D BN49_1419 acrA; highly similar to acriflavine resistance protein A from Escherichia coli O6 (tr|Q8CWA9) K03585 acrA; membrane fusion protein, multidrug efflux system
D BN49_0069 unnamed protein product; highly similar to acriflavine resistance protein A from Escherichia coli O6 K03585 acrA; membrane fusion protein, multidrug efflux system
C Inhibitors of FtsZ assembly
D BN49_3423 minC; highly similar to probable septum site-determining protein MinC from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TAX3) K03610 minC; septum site-determining protein MinC
D BN49_3424 minD; highly similar to cell division inhibitor, membrane ATPase MinD from Escherichia coli strain UTI89 - UPEC (tr|Q1RCS2) K03609 minD; septum site-determining protein MinD
D BN49_3425 minE; highly similar to cell division topological specificity factor from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TAX5) K03608 minE; cell division topological specificity factor
D BN49_2081 sulA; highly similar to cell division inhibitor SulA from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6T752) K13053 sulA; cell division inhibitor SulA
D BN49_0124 slmA; highly similar to HTH-type protein SlmA from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TFN2) K05501 slmA; TetR/AcrR family transcriptional regulator
C Other chromosome partitioning proteins
D BN49_1764 seqA; highly similar to negative modulator of initiation of replication from Escherichia coli O44:H18 strain 042 - EAEC (tr|D3GXD9) K03645 seqA; negative modulator of initiation of replication
D BN49_0461 mreB; highly similar to putative rod shape-determining protein MreB from Citrobacter sp. (tr|C1MA49) K03569 mreB; rod shape-determining protein MreB and related proteins
D BN49_0462 mreC; highly similar to putative rod shape-determining protein MreC from Escherichia coli strain K12 (sp|P16926) K03570 mreC; rod shape-determining protein MreC
D BN49_0463 mreD; highly similar to putative rod shape-determining protein MreD from Salmonella dublin (tr|B5FIV0) K03571 mreD; rod shape-determining protein MreD
D BN49_1726 rodA; highly similar to rod shape-determining protein RodA from Escherichia coli O55:H7 strain CB9615 - EPEC (tr|D3QLS6) K05837 rodA; rod shape determining protein RodA
D BN49_pI0104 parA; highly similar to putative plasmid partition protein A from Salmonella enterica (tr|B5P979) K03496 parA; chromosome partitioning protein
D BN49_pII0013 sopA; highly similar to plasmid partition protein A from Escherichia coli strain K12 (sp|P62556) K03496 parA; chromosome partitioning protein
D BN49_pI0015 unnamed protein product; highly similar to putative ParB-like partition protein from Salmonella enterica (tr|B5MTX8) K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
D BN49_pII0012 sopB; highly similar to plasmid partition protein B from Escherichia coli strain K12 (sp|P62558) K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
D BN49_2600 unnamed protein product; similar to putative chromosome partitioning protein gp35 from Burkholderia phage KS9 (tr|C7BGF1) K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
D BN49_0671 parC; highly similar to DNA topoisomerase 4 subunit A from Shigella flexneri (sp|P0AFI4) K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]
D BN49_0664 parE; highly similar to DNA topoisomerase 4 subunit B from Salmonella typhimurium (sp|P0A2I5) K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]
D BN49_5061 mnmG; highly similar to tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TG45) K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D BN49_5062 rsmG; highly similar to ribosomal RNA small subunit methyltransferase G from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TG44) K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]
D BN49_4553 xerC; highly similar to tyrosine recombinase XerC from Salmonella typhimurium (sp|P55888) K03733 xerC; integrase/recombinase XerC
D BN49_0766 xerD; highly similar to site-specific tyrosine recombinase from Escherichia coli O7:K1 strain IAI39 - ExPEC (tr|B7NW35) K04763 xerD; integrase/recombinase XerD
D BN49_3776 unnamed protein product; highly similar to putative ATPase from Escherichia coli strain UTI89 - UPEC (tr|Q1R9V9) K03593 mrp; ATP-binding protein involved in chromosome partitioning
D BN49_0370 unnamed protein product; highly similar to probable adenosine monophosphate-protein transferase Fic from Salmonella typhimurium (sp|P20751) K04095 fic; cell filamentation protein, protein adenylyltransferase [EC:2.7.7.108]
D BN49_4689 engB; highly similar to probable GTP-binding protein EngB from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TG68) K03978 engB; GTP-binding protein
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: January 17, 2023