+E Messenger RNA Biogenesis KO
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Messenger RNA Biogenesis - Nothoprocta perdicaria (Chilean tinamou)
%
!
AEukaryotic type
B mRNA processing factors
C 5' end processing
D Capping factors
E 112948219 RNMT; mRNA cap guanine-N7 methyltransferase K00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56]
E 112946564 RNGTT; mRNA-capping enzyme isoform X1 K13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]
E 112944097 CDK7; cyclin-dependent kinase 7 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E 112957548 CMTR1; cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 K14589 CMTR1; cap1 methyltransferase [EC:2.1.1.57]
E 112943265 CMTR2; cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 K14590 CMTR2; cap2 methyltransferase [EC:2.1.1.296]
E 112952852 RAMAC; RNMT-activating mRNA cap methyltransferase subunit isoform X1 K18708 FAM103A1; RNMT-activating mini protein
D Cap binding complex
E 112948919 NCBP1; nuclear cap-binding protein subunit 1 K12882 NCBP1; nuclear cap-binding protein subunit 1
E 112947467 NCBP2; nuclear cap-binding protein subunit 2 K12883 NCBP2; nuclear cap-binding protein subunit 2
E 112948677 nuclear cap-binding protein subunit 2 K12883 NCBP2; nuclear cap-binding protein subunit 2
C 3' end processing
D Pre-mRNA cleavage factor Im (CFIm)
E 112943194 NUDT21; cleavage and polyadenylation specificity factor subunit 5 K14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5
E 112952738 CPSF7; cleavage and polyadenylation specificity factor subunit 7 K14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6/7
E 112958823 CPSF6; cleavage and polyadenylation specificity factor subunit 6 isoform X1 K14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6/7
D Pre-mRNA cleavage factor IIm (CFIIm)
E 112948016 CLP1; polyribonucleotide 5'-hydroxyl-kinase Clp1 K14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]
E 112943685 PCF11; pre-mRNA cleavage complex 2 protein Pcf11 isoform X1 K14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11
D Cleavage and polyadenylation specificity factor (CPSF) complex
E 112953572 CPSF2; cleavage and polyadenylation specificity factor subunit 2 K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E 112945463 CPSF3; cleavage and polyadenylation specificity factor subunit 3 isoform X1 K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E 112959855 CPSF4; cleavage and polyadenylation specificity factor subunit 4 K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4
E 112945304 CPSF4L; putative cleavage and polyadenylation specificity factor subunit 4-like protein K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4
E 112942652 FIP1L1; pre-mRNA 3'-end-processing factor FIP1 K14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1
E 112947062 pre-mRNA 3'-end-processing factor FIP1-like K14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1
E 112949216 WDR33; pre-mRNA 3' end processing protein WDR33 isoform X1 K15542 PFS2; polyadenylation factor subunit 2
E 112953011 WDR82; WD repeat-containing protein 82 K14962 WDR82; COMPASS component SWD2
E 112949378 PPP1CC; serine/threonine-protein phosphatase PP1-gamma catalytic subunit K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 112957826 PPP1CA; serine/threonine-protein phosphatase PP1-alpha catalytic subunit K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 112953209 PPP1CB; serine/threonine-protein phosphatase PP1-beta catalytic subunit K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 112957372 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]
D Cleavage stimulation factor (CSTF) complex
E 112949717 CSTF1; cleavage stimulation factor subunit 1 K14406 CSTF1; cleavage stimulation factor subunit 1
E 112944485 CSTF2; cleavage stimulation factor subunit 2 K14407 CSTF2; cleavage stimulation factor subunit 2
E 112948865 CSTF3; cleavage stimulation factor subunit 3 K14408 CSTF3; cleavage stimulation factor subunit 3
D U7-dependent histone pre-mRNA processing factors
E 112955036 SNRPB; small nuclear ribonucleoprotein-associated proteins B and B' isoform X1 K11086 SNRPB; small nuclear ribonucleoprotein B and B'
E 112946047 SNRPD3; small nuclear ribonucleoprotein Sm D3 K11088 SNRPD3; small nuclear ribonucleoprotein D3
E 112959263 SNRPE; small nuclear ribonucleoprotein E K11097 SNRPE; small nuclear ribonucleoprotein E
E 112959454 SNRPF; small nuclear ribonucleoprotein F K11098 SNRPF; small nuclear ribonucleoprotein F
E 112950497 SNRPG; small nuclear ribonucleoprotein G K11099 SNRPG; small nuclear ribonucleoprotein G
E 112950931 LSM10; U7 snRNA-associated Sm-like protein LSm10 K25591 LSM10; U7 snRNA-associated Sm-like protein LSm10
E 112954348 LSM11; U7 snRNA-associated Sm-like protein LSm11 K25592 LSM11; U7 snRNA-associated Sm-like protein LSm11
E 112953572 CPSF2; cleavage and polyadenylation specificity factor subunit 2 K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E 112945463 CPSF3; cleavage and polyadenylation specificity factor subunit 3 isoform X1 K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E 112944485 CSTF2; cleavage stimulation factor subunit 2 K14407 CSTF2; cleavage stimulation factor subunit 2
E 112943044 SLBP; histone RNA hairpin-binding protein K18710 SLBP; histone RNA hairpin-binding protein
E 112943052 uncharacterized protein LOC112943052 isoform X1 K18710 SLBP; histone RNA hairpin-binding protein
E 112953211 oocyte-specific histone RNA stem-loop-binding protein 2-like K18710 SLBP; histone RNA hairpin-binding protein
E 112946571 CASP8AP2; CASP8-associated protein 2 K25593 CASP8AP2; CASP8-associated protein 2
D DRB sensitivity inducing factor (DSIF) complex
E 112956705 SUPT4H1; transcription elongation factor SPT4 K15171 SUPT4H1; transcription elongation factor SPT4
E 112957729 SUPT5H; transcription elongation factor SPT5 K15172 SUPT5H; transcription elongation factor SPT5
D N6-methyltransferase complex
E 112955612 METTL3; N6-adenosine-methyltransferase catalytic subunit K05925 METTL3; mRNA m6A methyltransferase catalytic subunit [EC:2.1.1.348]
E 112943446 METTL14; N6-adenosine-methyltransferase non-catalytic subunit K23960 METTL14; mRNA m6A methyltransferase non-catalytic subunit
E 112944107 METTL4; methyltransferase-like protein 4 K24174 METTL4; N(6)-adenine-specific DNA methyltransferase [EC:2.1.1.72]
E 112956853 METTL16; U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase K11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346]
E 112951983 WTAP; pre-mRNA-splicing regulator WTAP K22824 WTAP; pre-mRNA-splicing regulator WTAP
E 112956483 VIRMA; protein virilizer homolog K22910 VIRMA; protein virilizer
E 112949123 RBM15B; putative RNA-binding protein 15B K13190 RBM15; RNA-binding protein 15
E 112944599 RBM15; RNA-binding protein 15 K13190 RBM15; RNA-binding protein 15
E 112950351 ZC3H13; zinc finger CCCH domain-containing protein 13 isoform X1 K22909 ZC3H13; zinc finger CCCH domain-containing protein 13
E 112953374 CBLL1; E3 ubiquitin-protein ligase Hakai isoform X1 K15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]
D Poly(A) addition factors
E 112956952 PAPOLA; poly(A) polymerase alpha isoform X1 K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
E 112944934 PAPOLG; poly(A) polymerase gamma isoform X1 K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
E 112945185 TENT2; poly(A) RNA polymerase GLD2 isoform X1 K14079 PAPD4; poly(A) RNA polymerase GLD2 [EC:2.7.7.19]
D Negative regulators of mRNA 3' end processing
E 112956001 BARD1; BRCA1-associated RING domain protein 1 K10683 BARD1; BRCA1-associated RING domain protein 1
E 112951744 RBM26; RNA-binding protein 26 isoform X1 K13192 RBM26; RNA-binding protein 26
E 112945012 FTO; alpha-ketoglutarate-dependent dioxygenase FTO K19469 FTO; mRNA N6-methyladenine demethylase [EC:1.14.11.53]
E 112959929 ALKBH5; RNA demethylase ALKBH5 K10767 ALKBH5; mRNA N6-methyladenine demethylase [EC:1.14.11.53]
E 112959577 TARDBP; TAR DNA-binding protein 43 K23600 TARDBP; TAR DNA-binding protein 43
C Other processing factors
D 112954613 DHX40; probable ATP-dependent RNA helicase DHX40 K18711 DHX40; ATP-dependent RNA helicase DHX40 [EC:3.6.4.13]
D 112958561 KIN; DNA/RNA-binding protein KIN17 isoform X1 K13102 KIN; DNA/RNA-binding protein KIN17
D 112951770 METTL8; methyltransferase-like protein 8 isoform X1 K24975 METTL8; mRNA N(3)-methylcytidine methyltransferase METTL8 [EC:2.1.1.-]
D 112955731 METTL22; methyltransferase-like protein 22 isoform X1 K23040 METTL22; methyltransferase-like protein 22 [EC:2.1.1.-]
D 112946570 TENT5A; terminal nucleotidyltransferase 5A K23033 TENT5A_B; terminal nucleotidyltransferase 5A/B [EC:2.7.7.-]
D 112950892 TENT5B; terminal nucleotidyltransferase 5B K23033 TENT5A_B; terminal nucleotidyltransferase 5A/B [EC:2.7.7.-]
D 112960136 TENT5C; terminal nucleotidyltransferase 5C K23034 TENT5C; terminal nucleotidyltransferase 5C [EC:2.7.7.19]
D 112942306 TENT5D; terminal nucleotidyltransferase 5D isoform X1 K23035 TENT5D; terminal nucleotidyltransferase 5D [EC:2.7.7.19]
D 112951919 ZC3H14; zinc finger CCCH domain-containing protein 14 isoform X1 K23038 ZC3H14; zinc finger CCCH domain-containing protein 14
B mRNA surveillance and transport factors
C Transport factors
D EJC complex
E 112953586 RBM8A; RNA-binding protein 8A K12876 RBM8A; RNA-binding protein 8A
E 112943791 MAGOH; protein mago nashi homolog K12877 MAGOH; protein mago nashi
E 112945272 ALYREF; THO complex subunit 4 K12881 THOC4; THO complex subunit 4
E 112956989 DDX39B; spliceosome RNA helicase DDX39B K12812 DDX39B; ATP-dependent RNA helicase UAP56/SUB2 [EC:3.6.4.13]
E 112942948 EIF4A3; eukaryotic initiation factor 4A-III K13025 EIF4A3; ATP-dependent RNA helicase [EC:3.6.4.13]
E 112958787 CCDC174; coiled-coil domain-containing protein 174 isoform X1 K25178 CCDC174; coiled-coil domain-containing protein 174
E 112949016 CASC3; protein CASC3 K14323 CASC3; protein CASC3
E 112950112 SAP18; histone deacetylase complex subunit SAP18 K14324 SAP18; histone deacetylase complex subunit SAP18
E 112957981 PNN; pinin K13114 PNN; pinin
E 112950437 RNPS1; RNA-binding protein with serine-rich domain 1 K14325 RNPS1; RNA-binding protein with serine-rich domain 1
E 112950725 SRRM1; serine/arginine repetitive matrix protein 1 K13171 SRRM1; serine/arginine repetitive matrix protein 1
D TREX complex
E 112944038 THOC1; THO complex subunit 1 isoform X1 K12878 THOC1; THO complex subunit 1
E 112944487 THOC2; THO complex subunit 2 K12879 THOC2; THO complex subunit 2
E 112954410 THOC3; THO complex subunit 3 K12880 THOC3; THO complex subunit 3
E 112945272 ALYREF; THO complex subunit 4 K12881 THOC4; THO complex subunit 4
E 112950366 THOC5; THO complex subunit 5 homolog K13174 THOC5; THO complex subunit 5
E 112958784 THOC7; THO complex subunit 7 homolog K13176 THOC7; THO complex subunit 7
D TREX-2 complex
E 112951594 PCID2; PCI domain-containing protein 2 K23801 PCID2; nuclear mRNA export protein PCID2/THP1
E 112944760 SEM1; 26S proteasome complex subunit SEM1 K10881 SHFM1; 26 proteasome complex subunit DSS1
E 112960343 ENY2; transcription and mRNA export factor ENY2 K11368 ENY2; enhancer of yellow 2 transcription factor
E 112947041 centrin-2 K10840 CETN2; centrin-2
E 112947042 caltractin-like K10840 CETN2; centrin-2
E 112949430 CETN3; centrin-3 K16466 CETN3; centrin-3
E 112955280 MCM3AP; germinal-center associated nuclear protein K24317 MCM3AP; germinal-center associated nuclear protein [EC:2.3.1.48]
D Nuclear pore complex
E 112951119 TPR; nucleoprotein TPR isoform X1 K09291 TPR; nucleoprotein TPR
E 112949694 RAE1; mRNA export factor K14298 RAE1; mRNA export factor
E 112958642 SEC13; protein SEC13 homolog K14004 SEC13; protein transport protein SEC13
E 112946625 NUP37; nucleoporin Nup37 K14302 NUP37; nuclear pore complex protein Nup37
E 112953771 NUP85; nuclear pore complex protein Nup85 K14304 NUP85; nuclear pore complex protein Nup85
E 112951664 NUP43; nucleoporin Nup43 K14305 NUP43; nuclear pore complex protein Nup43
E 112956886 NUP50; nuclear pore complex protein Nup50 K14295 NUP50; nuclear pore complex protein Nup50
E 112950267 NUP54; nucleoporin p54 K14308 NUP54; nuclear pore complex protein Nup54
E 112944479 NUP62CL; nucleoporin-62 C-terminal-like protein K14306 NUP62; nuclear pore complex protein Nup62
E 112956735 NUP88; nuclear pore complex protein Nup88 K14318 NUP88; nuclear pore complex protein Nup88
E 112943250 NUP93; nuclear pore complex protein Nup93 K14309 NUP93; nuclear pore complex protein Nup93
E 112955769 NUP98; nuclear pore complex protein Nup98-Nup96 isoform X1 K14297 NUP98; nuclear pore complex protein Nup98-Nup96
E 112958839 NUP107; nuclear pore complex protein Nup107 K14301 NUP107; nuclear pore complex protein Nup107
E 112959354 NUP133; nuclear pore complex protein Nup133 K14300 NUP133; nuclear pore complex protein Nup133
E 112955843 NUP188; nucleoporin NUP188 homolog K14311 NUP188; nuclear pore complex protein Nup188
E 112953906 NUP153; nuclear pore complex protein Nup153 K14296 NUP153; nuclear pore complex protein Nup153
E 112946141 NUP155; nuclear pore complex protein Nup155 isoform X1 K14312 NUP155; nuclear pore complex protein Nup155
E 112954040 NUP160; nuclear pore complex protein Nup160 K14303 NUP160; nuclear pore complex protein Nup160
E 112958240 NUP35; nucleoporin NUP35 K14313 NUP35; nuclear pore complex protein Nup53
E 112959486 NUP205; nuclear pore complex protein Nup205 isoform X1 K14310 NUP205; nuclear pore complex protein Nup205
E 112950648 NUP210L; nuclear pore membrane glycoprotein 210-like K14314 NUP210; nuclear pore complex protein Nup210
E 112953121 NUP210; nuclear pore membrane glycoprotein 210 K14314 NUP210; nuclear pore complex protein Nup210
E 112955880 NUP214; nuclear pore complex protein Nup214 isoform X1 K14317 NUP214; nuclear pore complex protein Nup214
E 112956678 nuclear envelope pore membrane protein POM 121C-like K14316 POM121; nuclear pore complex protein Nup121
E 112956308 NUP58; nucleoporin p58/p45 K14307 NUPL1; nucleoporin p58/p45
E 112942421 NUPL2; nucleoporin-like protein 2 K14321 NUPL2; nucleoporin-like protein 2
E 112943318 NDC1; nucleoporin NDC1 K14315 NDC1; nucleoporin NDC1
E 112948225 SEH1L; nucleoporin SEH1 K14299 SEH1; nucleoporin SEH1
E 112943325 RGPD4; ranBP2-like and GRIP domain-containing protein 4 isoform X1 K12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]
E 112944901 SENP2; sentrin-specific protease 2 K03345 SENP2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]
E 112952241 AAAS; aladin K14320 AAAS; aladin
E 112949430 CETN3; centrin-3 K16466 CETN3; centrin-3
E 112955976 GLE1; nucleoporin GLE1 K18723 GLE1; nucleoporin GLE1
E 112958221 nuclear RNA export factor 1-like K14284 NXF; nuclear RNA export factor
E 112944534 NXT2; NTF2-related export protein 2 isoform X1 K14285 NXT1_2; NTF2-related export protein 1/2
D Ran-mediated transport factors
E 112945908 RAN; GTP-binding nuclear protein Ran K07936 RAN; GTP-binding nuclear protein Ran
E 112948289 ANP32A; acidic leucine-rich nuclear phosphoprotein 32 family member A K18646 ANP32A_C_D; acidic leucine-rich nuclear phosphoprotein 32 family member A/C/D
E 112949083 acidic leucine-rich nuclear phosphoprotein 32 family member B isoform X1 K18647 ANP32B; acidic leucine-rich nuclear phosphoprotein 32 family member B
E 112943932 ELAVL1; ELAV-like protein 1 isoform X1 K13088 ELAVL1; ELAV-like protein 1
E 112953300 ELAVL2; ELAV-like protein 2 isoform X1 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 112942945 ELAVL4; ELAV-like protein 4 isoform X1 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 112954403 FAF2; FAS-associated factor 2 K18726 FAF2; FAS-associated factor 2
E 112947635 VCP; transitional endoplasmic reticulum ATPase K13525 VCP; transitional endoplasmic reticulum ATPase
E 112957808 VCPKMT; protein-lysine methyltransferase METTL21D isoform X1 K21806 VCPKMT; protein N-lysine methyltransferase METTL21D [EC:2.1.1.-]
E 112958962 XPO1; exportin-1 K14290 XPO1; exportin-1
E 112952926 XPO7; exportin-7 K18460 XPO7; exportin-7
E 112944290 RANBP17; ran-binding protein 17 K24115 RANBP17; Ran-binding protein 17
E 112946466 RANGAP1; ran GTPase-activating protein 1 K14319 RANGAP1; Ran GTPase-activating protein 1
E 112945381 TAF15; TATA-binding protein-associated factor 2N K14651 TAF15; transcription initiation factor TFIID subunit 15
D eIF4F and regulatory proteins
E 112954414 EIF4E1B; eukaryotic translation initiation factor 4E type 1B K03259 EIF4E; translation initiation factor 4E
E 112952005 EIF4E; eukaryotic translation initiation factor 4E K03259 EIF4E; translation initiation factor 4E
E 112952529 EIF4E2; eukaryotic translation initiation factor 4E type 2 isoform X1 K03259 EIF4E; translation initiation factor 4E
E 112952469 EIF4A2; eukaryotic initiation factor 4A-II K03257 EIF4A; translation initiation factor 4A
E 112943573 EIF4G2; eukaryotic translation initiation factor 4 gamma 2 K03260 EIF4G; translation initiation factor 4G
E 112957349 EIF4G3; eukaryotic translation initiation factor 4 gamma 3 K03260 EIF4G; translation initiation factor 4G
E 112952410 EIF4G1; eukaryotic translation initiation factor 4 gamma 1 K03260 EIF4G; translation initiation factor 4G
E 112955323 EIF4B; eukaryotic translation initiation factor 4B isoform X1 K03258 EIF4B; translation initiation factor 4B
E 112956736 EIF4H; eukaryotic translation initiation factor 4H isoform X1 K24086 EIF4H; translation initiation factor 4H
E 112950756 EIF4EBP1; eukaryotic translation initiation factor 4E-binding protein 1 K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
E 112944320 EIF4EBP3; eukaryotic translation initiation factor 4E-binding protein 3 K18645 EIF4EBP3; eukaryotic translation initiation factor 4E binding protein 3
E 112945909 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter isoform X1 K18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter
E 112954991 ANGEL1; protein angel homolog 1 K18729 ANGEL; protein angel
E 112955146 ANGEL2; protein angel homolog 2 K18729 ANGEL; protein angel
E 112952578 FXR1; fragile X mental retardation syndrome-related protein 1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 112946955 FMR1; synaptic functional regulator FMR1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 112954275 CYFIP2; cytoplasmic FMR1-interacting protein 2 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 112943123 CYFIP1; cytoplasmic FMR1-interacting protein 1 isoform X1 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 112954356 GEMIN5; gem-associated protein 5 K13133 GEMIN5; gem associated protein 5
E 112943076 TACC3; transforming acidic coiled-coil-containing protein 3 K14283 TACC3; transforming acidic coiled-coil-containing protein 3
E 112954488 CPEB4; cytoplasmic polyadenylation element-binding protein 4 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 112951272 CPEB1; cytoplasmic polyadenylation element-binding protein 1 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 112957612 CPEB3; cytoplasmic polyadenylation element-binding protein 3 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 112958518 CPEB2; cytoplasmic polyadenylation element-binding protein 2 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 112950339 DDX3X; ATP-dependent RNA helicase DDX3X K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:3.6.4.13]
E 112949200 GIGYF2; GRB10-interacting GYF protein 2 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 112949635 PABPC1L; polyadenylate-binding protein 1-like K13126 PABPC; polyadenylate-binding protein
E 112956525 PABPC1; polyadenylate-binding protein 1 K13126 PABPC; polyadenylate-binding protein
E 112950747 PABPC4; polyadenylate-binding protein 4 K13126 PABPC; polyadenylate-binding protein
E 112945890 PAIP1; polyadenylate-binding protein-interacting protein 1 K14322 PAIP1; polyadenylate-binding protein-interacting protein 1
E 112952060 DEAF1; deformed epidermal autoregulatory factor 1 homolog isoform X1 K23041 DEAF1; deformed epidermal autoregulatory factor 1
E 112944498 MCTS1; malignant T-cell-amplified sequence 1 isoform X1 K07575 MCTS; malignant T-cell-amplified sequence
E 112945892 DENR; density-regulated protein K24272 DENR; density-regulated protein
D APOBEC1-ACF complex
E 112948415 A1CF; APOBEC1 complementation factor isoform X1 K24978 A1CF; APOBEC1 complementation factor
D Other transport factors
E 112955598 PYM1; partner of Y14 and mago K14294 WIBG; partner of Y14 and mago
E 112956392 heterogeneous nuclear ribonucleoprotein A1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 112958248 HNRNPA3; heterogeneous nuclear ribonucleoprotein A3 isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 112954712 MSI2; RNA-binding protein Musashi homolog 2 isoform X1 K14411 MSI; RNA-binding protein Musashi
E 112945980 MSI1; RNA-binding protein Musashi homolog 1 isoform X1 K14411 MSI; RNA-binding protein Musashi
E 112946912 DAZAP1; DAZ-associated protein 1 isoform X1 K14411 MSI; RNA-binding protein Musashi
E 112954907 HBS1L; HBS1-like protein K14416 HBS1; elongation factor 1 alpha-like protein
E 112945863 PELO; protein pelota homolog K06965 PELO; protein pelota
E 112949944 PABPN1L; embryonic polyadenylate-binding protein 2 K14396 PABPN1; polyadenylate-binding protein 2
E 112959578 ATP-dependent RNA helicase DDX19B K18655 DDX19; ATP-dependent RNA helicase DDX19/DBP5 [EC:3.6.4.13]
E 112955759 DDX25; ATP-dependent RNA helicase DDX25 isoform X1 K18656 DDX25; ATP-dependent RNA helicase DDX25 [EC:3.6.4.13]
E 112954237 SARNP; SAP domain-containing ribonucleoprotein K18732 SARNP; SAP domain-containing ribonucleoprotein
E 112951863 RCC1; regulator of chromosome condensation K11493 RCC1; regulator of chromosome condensation
E 112949081 la-related protein 6-like K18733 LARP6; la-related protein 6
E 112958646 LARP6; la-related protein 6 K18733 LARP6; la-related protein 6
E 112944340 PURA; transcriptional activator protein Pur-alpha K21772 PURA; transcriptional activator protein Pur-alpha
E 112953825 POLDIP3; polymerase delta-interacting protein 3 isoform X1 K22414 POLDIP3; polymerase delta-interacting protein 3
E 112959264 ZC3H11A; LOW QUALITY PROTEIN: zinc finger CCCH domain-containing protein 11A K22415 ZC3H11; zinc finger CCCH domain-containing protein 11
E 112958819 LENG8; leukocyte receptor cluster member 8 K23802 LENG8; SAC3 family protein LENG8/THP3
E 112951297 PATL2; protein PAT1 homolog 2 K24823 PATL2; protein PAT1 homolog 2
C Surveillance factors
D Surveillance complex
E 112944321 ETF1; eukaryotic peptide chain release factor subunit 1 K03265 ETF1; peptide chain release factor subunit 1
E 112950422 GSPT1; eukaryotic peptide chain release factor GTP-binding subunit ERF3A K03267 ERF3; peptide chain release factor subunit 3
E 112946882 UPF1; regulator of nonsense transcripts 1 isoform X1 K14326 UPF1; regulator of nonsense transcripts 1 [EC:3.6.4.13 5.6.2.3]
E 112942395 UPF2; regulator of nonsense transcripts 2 isoform X1 K14327 UPF2; regulator of nonsense transcripts 2
E 112947109 UPF3B; regulator of nonsense transcripts 3B K14328 UPF3; regulator of nonsense transcripts 3
E 112954970 UPF3A; regulator of nonsense transcripts 3A K14328 UPF3; regulator of nonsense transcripts 3
D Protein phosphatase 2A
E 112953464 PPP2CB; serine/threonine-protein phosphatase 2A catalytic subunit beta isoform K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E 112952396 PPP2CA; serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E 112942999 PPP2R2C; protein phosphatase 2, regulatory subunit B, gamma K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 112944711 PPP2R2D; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 112950678 PPP2R2A; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform isoform X1 K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 112953161 PPP2R2B; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform isoform X1 K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 112953484 PPP2R3A; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 112943129 PPP2R3B; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta isoform X1 K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 112958031 PPP2R3C; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 112959671 PPP2R5E; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 112949327 PPP2R5D; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform isoform X1 K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 112955163 PPP2R5A; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 112956925 PPP2R5C; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X1 K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
D Other surveillance factors
E 112960045 SMG1; serine/threonine-protein kinase SMG1 K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
E 112953589 SMG5; protein SMG5 K11125 SMG5; protein SMG5
E 112954719 SMG6; telomerase-binding protein EST1A isoform X1 K11124 SMG6; protein SMG6 [EC:3.1.-.-]
E 112951521 SMG7; protein SMG7 isoform X1 K14409 SMG7; protein SMG7
E 112954646 SMG8; protein SMG8 K18734 SMG8; protein SMG8
E 112949200 GIGYF2; GRB10-interacting GYF protein 2 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 112959402 SECISBP2; selenocysteine insertion sequence-binding protein 2 K19539 SECISBP2; selenocysteine insertion sequence-binding protein 2
E 112956543 DHX34; probable ATP-dependent RNA helicase DHX34 K20101 DHX34; ATP-dependent RNA helicase DHX34 [EC:3.6.4.13]
E 112947771 GTPBP1; GTP-binding protein 1 K24887 GTPBP1; GTP-binding protein 1
C Factors involved in mRNA localization
D Cargo complex
E 112951039 PUM3; pumilio homolog 3 K14844 PUF6; pumilio homology domain family member 6
E 112947718 MYO5B; unconventional myosin-Vb isoform X1 K10357 MYO5; myosin V
E 112943919 unconventional myosin-Vb-like K10357 MYO5; myosin V
E 112952853 MYO5A; unconventional myosin-Va isoform X1 K10357 MYO5; myosin V
E 112952868 MYO5C; LOW QUALITY PROTEIN: unconventional myosin-Vc K10357 MYO5; myosin V
E 112948137 BICD1; protein bicaudal D homolog 1 K18739 BICD; protein bicaudal D
E 112953021 BICD2; protein bicaudal D homolog 2 K18739 BICD; protein bicaudal D
E 112942504 EXD1; piRNA biogenesis protein EXD1 isoform X1 K18740 EXD1; exonuclease 3'-5' domain-containing protein 1
D Factors that have mRNA localization signals
E 112959944 ACTB; actin, cytoplasmic 1 K05692 ACTB_G1; actin beta/gamma 1
E 112950999 actin K05692 ACTB_G1; actin beta/gamma 1
E 112945270 ACTG1; actin, cytoplasmic 2 K05692 ACTB_G1; actin beta/gamma 1
E 112947642 MBP; myelin basic protein K17269 MBP; myelin basic protein
E 112947391 VIM; vimentin K07606 VIM; vimentin
E 112959422 MYC; myc proto-oncogene protein K04377 MYC; Myc proto-oncogene protein
E 112946883 GDF1; embryonic growth/differentiation factor 1 K05495 GDF1; growth differentiation factor 1
E 112945995 T-box-containing protein TBX6L-like K10180 TBX6; T-box protein 6
E 112957130 NANOS1; nanos homolog 1 K18741 NANOS1; protein nanos 1
D Trans-acting binding proteins
E 112956072 FUBP3; far upstream element-binding protein 3 K13210 FUBP; far upstream element-binding protein
E 112946108 FUBP1; far upstream element-binding protein 1 isoform X1 K13210 FUBP; far upstream element-binding protein
E 112958392 KHSRP; far upstream element-binding protein 2 K13210 FUBP; far upstream element-binding protein
E 112949502 EEF1A2; elongation factor 1-alpha 2 K03231 EEF1A; elongation factor 1-alpha
E 112957593 EEF1A1; elongation factor 1-alpha 1 K03231 EEF1A; elongation factor 1-alpha
E 112956624 EEF1G; elongation factor 1-gamma K03233 EEF1G; elongation factor 1-gamma
E 112942434 HNRNPA2B1; heterogeneous nuclear ribonucleoproteins A2/B1 isoform X1 K13158 HNRNPA2B1; heterogeneous nuclear ribonucleoprotein A2/B1
E 112947873 AGFG1; arf-GAP domain and FG repeat-containing protein 1 isoform X1 K15044 AGFG1; Arf-GAP domain and FG repeats-containing protein 1
E 112942819 STAU2; double-stranded RNA-binding protein Staufen homolog 2 isoform X1 K17597 STAU; double-stranded RNA-binding protein Staufen
E 112949508 STAU1; double-stranded RNA-binding protein Staufen homolog 1 isoform X1 K17597 STAU; double-stranded RNA-binding protein Staufen
E 112942420 IGF2BP3; insulin-like growth factor 2 mRNA-binding protein 3 K13197 IGF2BP3; insulin-like growth factor 2 mRNA-binding protein 3
E 112946915 PTBP1; polypyrimidine tract-binding protein 1 K13218 PTBP1; polypyrimidine tract-binding protein 1
E 112954488 CPEB4; cytoplasmic polyadenylation element-binding protein 4 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 112951272 CPEB1; cytoplasmic polyadenylation element-binding protein 1 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 112957612 CPEB3; cytoplasmic polyadenylation element-binding protein 3 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 112958518 CPEB2; cytoplasmic polyadenylation element-binding protein 2 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
D Other mRNA localization factors
E 112952578 FXR1; fragile X mental retardation syndrome-related protein 1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 112946955 FMR1; synaptic functional regulator FMR1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 112954275 CYFIP2; cytoplasmic FMR1-interacting protein 2 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 112943123 CYFIP1; cytoplasmic FMR1-interacting protein 1 isoform X1 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 112952256 PCBP2; poly(rC)-binding protein 2 isoform X1 K13162 PCBP2; poly(rC)-binding protein 2
E 112947534 poly(rC)-binding protein 3-like isoform X1 K21444 PCBP3_4; poly(rC)-binding protein 3/4
E 112955568 PCBP3; poly(rC)-binding protein 3 K21444 PCBP3_4; poly(rC)-binding protein 3/4
E 112953109 PCBP4; poly(rC)-binding protein 4 K21444 PCBP3_4; poly(rC)-binding protein 3/4
E 112943494 CAPRIN1; caprin-1 K18743 CAPRIN1; caprin-1
E 112948139 CAPRIN2; caprin-2 isoform X1 K18744 CAPRIN2; caprin-2
E 112957395 YBX1; nuclease-sensitive element-binding protein 1 isoform X1 K09276 YBX1; Y-box-binding protein 1
C mRNA cycle factors
D Common to processing body (P body) and stress granule
E 112947902 XRN1; 5'-3' exoribonuclease 1 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E 112954014 AGO2; protein argonaute-2 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 112950728 protein argonaute-1 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 112950834 protein argonaute-4 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 112950835 protein argonaute-3 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 112954414 EIF4E1B; eukaryotic translation initiation factor 4E type 1B K03259 EIF4E; translation initiation factor 4E
E 112952005 EIF4E; eukaryotic translation initiation factor 4E K03259 EIF4E; translation initiation factor 4E
E 112952529 EIF4E2; eukaryotic translation initiation factor 4E type 2 isoform X1 K03259 EIF4E; translation initiation factor 4E
E 112946882 UPF1; regulator of nonsense transcripts 1 isoform X1 K14326 UPF1; regulator of nonsense transcripts 1 [EC:3.6.4.13 5.6.2.3]
E 112950339 DDX3X; ATP-dependent RNA helicase DDX3X K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:3.6.4.13]
E 112948070 DDX6; probable ATP-dependent RNA helicase DDX6 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:3.6.4.13]
E 112953574 MEX3A; RNA-binding protein MEX3A K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 112952807 MEX3B; RNA-binding protein MEX3B K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 112946958 MEX3C; RNA-binding E3 ubiquitin-protein ligase MEX3C K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 112956375 FASTK; fas-activated serine/threonine kinase K08290 FASTK; Fas-activated serine/threonine kinase [EC:2.7.11.8]
E 112949572 LSM14B; protein LSM14 homolog B K18749 LSM14; protein LSM14
E 112945000 LSM14A; protein LSM14 homolog A isoform X1 K18749 LSM14; protein LSM14
E 112952256 PCBP2; poly(rC)-binding protein 2 isoform X1 K13162 PCBP2; poly(rC)-binding protein 2
E 112957395 YBX1; nuclease-sensitive element-binding protein 1 isoform X1 K09276 YBX1; Y-box-binding protein 1
E 112943621 LIMD1; LIM domain-containing protein 1 K16682 AJUBA; LIM domain-containing protein
E 112944999 WTIP; Wilms tumor protein 1-interacting protein K16682 AJUBA; LIM domain-containing protein
E 112944590 MOV10; putative helicase MOV-10 K18422 MOV10; helicase MOV-10 [EC:3.6.4.13]
E 112950744 PNRC2; proline-rich nuclear receptor coactivator 2 K18751 PNRC2; proline-rich nuclear receptor coactivator 2
E 112944754 TNPO1; transportin-1 K18752 TNPO1; transportin-1
E 112960045 SMG1; serine/threonine-protein kinase SMG1 K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
E 112953589 SMG5; protein SMG5 K11125 SMG5; protein SMG5
E 112954719 SMG6; telomerase-binding protein EST1A isoform X1 K11124 SMG6; protein SMG6 [EC:3.1.-.-]
E 112951521 SMG7; protein SMG7 isoform X1 K14409 SMG7; protein SMG7
E 112946392 ZFP36L1; mRNA decay activator protein ZFP36L1 K18753 ZFP36L; butyrate response factor
E 112950738 LIN28A; protein lin-28 homolog A K18754 LIN28; protein lin-28
E 112945125 LIN28B; protein lin-28 homolog B K18754 LIN28; protein lin-28
E 112943012 HTT; huntingtin isoform X1 K04533 HD; huntingtin
E 112948132 IPO8; importin-8 K18755 IPO8; importin-8
E 112950487 BICC1; protein bicaudal C homolog 1 K18756 BICC1; protein bicaudal C
E 112956392 heterogeneous nuclear ribonucleoprotein A1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 112958248 HNRNPA3; heterogeneous nuclear ribonucleoprotein A3 isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 112946238 PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X1 K04345 PKA; protein kinase A [EC:2.7.11.11]
E 112954412 LARP1; la-related protein 1 isoform X1 K18757 LARP1; la-related protein 1
E 112958160 LARP1B; la-related protein 1B isoform X1 K18757 LARP1; la-related protein 1
E 112949414 ATXN2; ataxin-2 isoform X1 K23625 ATXN2_2L; ataxin 2/2L
D P-body specific factors
E 112958913 DCP2; m7GpppN-mRNA hydrolase isoform X1 K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E 112953137 DCP1A; mRNA-decapping enzyme 1A K12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]
E 112958309 DCP1B; mRNA-decapping enzyme 1B isoform X1 K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]
E 112952908 LSM1; U6 snRNA-associated Sm-like protein LSm1 K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E 112958794 LSM3; U6 snRNA-associated Sm-like protein LSm3 K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 112946875 LSM4; U6 snRNA-associated Sm-like protein LSm4 K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4
E 112958472 LSM5; U6 snRNA-associated Sm-like protein LSm5 K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
E 112950184 LSM6; U6 snRNA-associated Sm-like protein LSm6 K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E 112943873 LSM7; U6 snRNA-associated Sm-like protein LSm7 K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E 112942320 LSM8; LSM8 homolog, U6 small nuclear RNA associated K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8
E 112955098 KLC4; kinesin light chain 4 isoform X1 K10407 KLC; kinesin light chain
E 112955353 KLC1; kinesin light chain 1 isoform X1 K10407 KLC; kinesin light chain
E 112947718 MYO5B; unconventional myosin-Vb isoform X1 K10357 MYO5; myosin V
E 112943919 unconventional myosin-Vb-like K10357 MYO5; myosin V
E 112952853 MYO5A; unconventional myosin-Va isoform X1 K10357 MYO5; myosin V
E 112952868 MYO5C; LOW QUALITY PROTEIN: unconventional myosin-Vc K10357 MYO5; myosin V
E 112947853 tubulin alpha-5 chain-like K07374 TUBA; tubulin alpha
E 112954233 tubulin alpha-1B chain K07374 TUBA; tubulin alpha
E 112954234 tubulin alpha-1A chain K07374 TUBA; tubulin alpha
E 112951603 tubulin alpha-3 chain K07374 TUBA; tubulin alpha
E 112951604 tubulin alpha-3 chain-like isoform X1 K07374 TUBA; tubulin alpha
E 112952427 tubulin alpha-3 chain K07374 TUBA; tubulin alpha
E 112958323 TUBA8; tubulin alpha-8 chain K07374 TUBA; tubulin alpha
E 112959211 tubulin alpha-8 chain K07374 TUBA; tubulin alpha
E 112954488 CPEB4; cytoplasmic polyadenylation element-binding protein 4 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 112951272 CPEB1; cytoplasmic polyadenylation element-binding protein 1 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 112957612 CPEB3; cytoplasmic polyadenylation element-binding protein 3 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 112958518 CPEB2; cytoplasmic polyadenylation element-binding protein 2 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 112954356 GEMIN5; gem-associated protein 5 K13133 GEMIN5; gem associated protein 5
E 112943076 TACC3; transforming acidic coiled-coil-containing protein 3 K14283 TACC3; transforming acidic coiled-coil-containing protein 3
E 112960007 TNRC6A; trinucleotide repeat-containing gene 6A protein K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 112957653 TNRC6C; trinucleotide repeat-containing gene 6C protein isoform X1 K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 112946441 TNRC6B; trinucleotide repeat-containing gene 6B protein K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 112943274 CNOT1; CCR4-NOT transcription complex subunit 1 isoform X1 K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E 112958828 CNOT2; CCR4-NOT transcription complex subunit 2 isoform X1 K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E 112958982 CNOT3; CCR4-NOT transcription complex subunit 3 K12580 CNOT3; CCR4-NOT transcription complex subunit 3
E 112959479 CNOT4; CCR4-NOT transcription complex subunit 4 isoform X1 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
E 112954282 CNOT6; CCR4-NOT transcription complex subunit 6 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 112950265 CNOT6L; CCR4-NOT transcription complex subunit 6-like K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 112954281 CNOT8; CCR4-NOT transcription complex subunit 8 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 112942582 CNOT7; CCR4-NOT transcription complex subunit 7 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 112952511 DIS3L2; DIS3-like exonuclease 2 K18758 DIS3L2; DIS3-like exonuclease 2 [EC:3.1.13.-]
E 112955626 PAN2; PAN2-PAN3 deadenylation complex catalytic subunit PAN2 K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]
E 112956293 PAN3; PAN2-PAN3 deadenylation complex subunit PAN3 isoform X1 K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
E 112953698 TOB1; protein Tob1 K14443 TOB; protein Tob/BTG
E 112948727 BTG4; protein BTG4 K14443 TOB; protein Tob/BTG
E 112944137 BTG1; protein BTG1 K14443 TOB; protein Tob/BTG
E 112946475 TOB2; protein Tob2 K14443 TOB; protein Tob/BTG
E 112953119 protein BTG1-like K14443 TOB; protein Tob/BTG
E 112959197 BTG2; protein BTG2 K14443 TOB; protein Tob/BTG
E 112945909 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter isoform X1 K18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter
E 112956836 PATL1; protein PAT1 homolog 1 K12617 PATL1; DNA topoisomerase 2-associated protein PAT1
E 112951030 EDC3; enhancer of mRNA-decapping protein 3 K12615 EDC3; enhancer of mRNA-decapping protein 3
E 112943229 EDC4; enhancer of mRNA-decapping protein 4 K12616 EDC4; enhancer of mRNA-decapping protein 4
E 112942395 UPF2; regulator of nonsense transcripts 2 isoform X1 K14327 UPF2; regulator of nonsense transcripts 2
E 112947109 UPF3B; regulator of nonsense transcripts 3B K14328 UPF3; regulator of nonsense transcripts 3
E 112954970 UPF3A; regulator of nonsense transcripts 3A K14328 UPF3; regulator of nonsense transcripts 3
E 112952632 TRIM71; E3 ubiquitin-protein ligase TRIM71 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
E 112956623 POLR2G; DNA-directed RNA polymerase II subunit RPB7 K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
E 112957570 EIF2AK2; interferon-induced, double-stranded RNA-activated protein kinase K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
E 112942587 ZAR1; LOW QUALITY PROTEIN: zygote arrest protein 1 K18762 ZAR1; zygote arrest protein 1
E 112956336 ZAR1L; ZAR1-like protein K18762 ZAR1; zygote arrest protein 1
E 112949798 YTHDF1; YTH domain-containing family protein 1 isoform X1 K20102 YTHDF; YTH domain-containing family protein
E 112944782 YTHDF3; YTH domain-containing family protein 3 K20102 YTHDF; YTH domain-containing family protein
E 112951870 YTHDF2; YTH domain-containing family protein 2 K20102 YTHDF; YTH domain-containing family protein
D Stress granule specific factors
E 112950397 TIA1; nucleolysin TIA-1 isoform X1 K13201 TIA1; nucleolysin TIA-1/TIAR
E 112957164 TIAL1; nucleolysin TIAR isoform X1 K13201 TIA1; nucleolysin TIA-1/TIAR
E 112949635 PABPC1L; polyadenylate-binding protein 1-like K13126 PABPC; polyadenylate-binding protein
E 112956525 PABPC1; polyadenylate-binding protein 1 K13126 PABPC; polyadenylate-binding protein
E 112950747 PABPC4; polyadenylate-binding protein 4 K13126 PABPC; polyadenylate-binding protein
E 112942819 STAU2; double-stranded RNA-binding protein Staufen homolog 2 isoform X1 K17597 STAU; double-stranded RNA-binding protein Staufen
E 112949508 STAU1; double-stranded RNA-binding protein Staufen homolog 1 isoform X1 K17597 STAU; double-stranded RNA-binding protein Staufen
E 112952578 FXR1; fragile X mental retardation syndrome-related protein 1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 112946955 FMR1; synaptic functional regulator FMR1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 112943932 ELAVL1; ELAV-like protein 1 isoform X1 K13088 ELAVL1; ELAV-like protein 1
E 112954299 G3BP1; ras GTPase-activating protein-binding protein 1 isoform X1 K17265 G3BP1; Ras GTPase-activating protein-binding protein 1 [EC:5.6.2.3 3.6.4.13]
E 112950069 G3BP2; ras GTPase-activating protein-binding protein 2 isoform X1 K24983 G3BP2; Ras GTPase-activating protein-binding protein 2
E 112952413 EIF2A; eukaryotic translation initiation factor 2A isoform X1 K15026 EIF2A; translation initiation factor 2A
E 112959884 EIF3B; eukaryotic translation initiation factor 3 subunit B K03253 EIF3B; translation initiation factor 3 subunit B
E 112952469 EIF4A2; eukaryotic initiation factor 4A-II K03257 EIF4A; translation initiation factor 4A
E 112942948 EIF4A3; eukaryotic initiation factor 4A-III K13025 EIF4A3; ATP-dependent RNA helicase [EC:3.6.4.13]
E 112955323 EIF4B; eukaryotic translation initiation factor 4B isoform X1 K03258 EIF4B; translation initiation factor 4B
E 112943573 EIF4G2; eukaryotic translation initiation factor 4 gamma 2 K03260 EIF4G; translation initiation factor 4G
E 112957349 EIF4G3; eukaryotic translation initiation factor 4 gamma 3 K03260 EIF4G; translation initiation factor 4G
E 112952410 EIF4G1; eukaryotic translation initiation factor 4 gamma 1 K03260 EIF4G; translation initiation factor 4G
E 112960385 RPS6KA6; ribosomal protein S6 kinase alpha-6 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 112950735 RPS6KA1; ribosomal protein S6 kinase alpha-1 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 112951968 RPS6KA2; ribosomal protein S6 kinase alpha-2 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 112958156 RPS6KA3; ribosomal protein S6 kinase alpha-3 isoform X1 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 112955061 receptor of activated protein C kinase 1-like K14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein
E 112956027 TRAF2; TNF receptor-associated factor 2 isoform X1 K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
E 112958221 nuclear RNA export factor 1-like K14284 NXF; nuclear RNA export factor
E 112943178 TDRD3; tudor domain-containing protein 3 isoform X1 K18404 TDRD3; tudor domain-containing protein 3
E 112944271 LARP4B; la-related protein 4B isoform X1 K18763 LARP4; la-related protein 4
E 112950303 LARP4; la-related protein 4 isoform X1 K18763 LARP4; la-related protein 4
B mRNA degradation factors
C 5'-3' decay
D Decapping complex
E 112953137 DCP1A; mRNA-decapping enzyme 1A K12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]
E 112958309 DCP1B; mRNA-decapping enzyme 1B isoform X1 K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]
E 112958913 DCP2; m7GpppN-mRNA hydrolase isoform X1 K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E 112948070 DDX6; probable ATP-dependent RNA helicase DDX6 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:3.6.4.13]
E 112951030 EDC3; enhancer of mRNA-decapping protein 3 K12615 EDC3; enhancer of mRNA-decapping protein 3
E 112943229 EDC4; enhancer of mRNA-decapping protein 4 K12616 EDC4; enhancer of mRNA-decapping protein 4
E 112956836 PATL1; protein PAT1 homolog 1 K12617 PATL1; DNA topoisomerase 2-associated protein PAT1
D Lsm complex
E 112952908 LSM1; U6 snRNA-associated Sm-like protein LSm1 K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E 112958794 LSM3; U6 snRNA-associated Sm-like protein LSm3 K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 112946875 LSM4; U6 snRNA-associated Sm-like protein LSm4 K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4
E 112958472 LSM5; U6 snRNA-associated Sm-like protein LSm5 K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
E 112950184 LSM6; U6 snRNA-associated Sm-like protein LSm6 K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E 112943873 LSM7; U6 snRNA-associated Sm-like protein LSm7 K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E 112942320 LSM8; LSM8 homolog, U6 small nuclear RNA associated K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8
D 5' exonucleases
E 112947902 XRN1; 5'-3' exoribonuclease 1 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E 112947212 XRN2; 5'-3' exoribonuclease 2 K12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]
D Other 5'-3' decay factors
E 112947250 DCPS; m7GpppX diphosphatase K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
E 112953769 HELZ; probable helicase with zinc finger domain isoform X1 K25168 HELZ; helicase with zinc finger domain [EC:3.6.4.-]
C 3'-5' decay
D Core exosome factors
E 112957098 EXOSC1; exosome complex component CSL4 K07573 CSL4; exosome complex component CSL4
E 112956109 EXOSC2; exosome complex component RRP4 K03679 RRP4; exosome complex component RRP4
E 112950449 EXOSC3; exosome complex component RRP40 K03681 RRP40; exosome complex component RRP40
E 112958815 exosome complex component RRP46-like K12590 RRP46; exosome complex component RRP46
E 112943628 EXOSC7; exosome complex component RRP42 K12589 RRP42; exosome complex component RRP42
E 112942891 EXOSC8; exosome complex component RRP43 K12586 RRP43; exosome complex component RRP43
E 112950228 EXOSC9; exosome complex component RRP45 isoform X1 K03678 RRP45; exosome complex component RRP45
D Exosome cofactors
E 112951752 DIS3; exosome complex exonuclease RRP44 K12585 DIS3; exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-]
E 112948318 DIS3L; DIS3-like exonuclease 1 isoform X1 K18681 DIS3L; DIS3-like exonuclease 1 [EC:3.1.13.-]
E 112959528 EXOSC10; exosome component 10 K12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-]
E 112942933 C1D; nuclear nucleic acid-binding protein C1D K12592 C1D; exosome complex protein LRP1
E 112949886 MPHOSPH6; M-phase phosphoprotein 6 K12593 MPHOSPH6; M-phase phosphoprotein 6, animal type
E 112955361 probable ATP-dependent RNA helicase DDX60 K20103 DDX60; ATP-dependent RNA helicase DDX60 [EC:3.6.4.13]
D TRAMP complex
E 112955266 TENT4A; non-canonical poly(A) RNA polymerase PAPD7 isoform X1 K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
E 112944953 TENT4B; non-canonical poly(A) RNA polymerase PAPD5 K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
E 112946282 ZCCHC7; zinc finger CCHC domain-containing protein 7 K12597 AIR1_2; protein AIR1/2
E 112945734 MTREX; exosome RNA helicase MTR4 K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:3.6.4.13]
D Ski complex
E 112951405 TTC37; tetratricopeptide repeat protein 37 K12600 SKI3; superkiller protein 3
E 112946721 WDR61; WD repeat-containing protein 61 K12602 WDR61; WD repeat-containing protein 61
D Ccr4-NOT complex
E 112954282 CNOT6; CCR4-NOT transcription complex subunit 6 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 112950265 CNOT6L; CCR4-NOT transcription complex subunit 6-like K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 112943274 CNOT1; CCR4-NOT transcription complex subunit 1 isoform X1 K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E 112958828 CNOT2; CCR4-NOT transcription complex subunit 2 isoform X1 K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E 112958982 CNOT3; CCR4-NOT transcription complex subunit 3 K12580 CNOT3; CCR4-NOT transcription complex subunit 3
E 112959479 CNOT4; CCR4-NOT transcription complex subunit 4 isoform X1 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
E 112954281 CNOT8; CCR4-NOT transcription complex subunit 8 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 112942582 CNOT7; CCR4-NOT transcription complex subunit 7 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 112959498 CNOT9; CCR4-NOT transcription complex subunit 9 isoform X1 K12606 RCD1; CCR4-NOT transcription complex subunit 9
E 112952628 CNOT10; CCR4-NOT transcription complex subunit 10 K12607 CNOT10; CCR4-NOT transcription complex subunit 10
D Pan complex
E 112955626 PAN2; PAN2-PAN3 deadenylation complex catalytic subunit PAN2 K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]
E 112956293 PAN3; PAN2-PAN3 deadenylation complex subunit PAN3 isoform X1 K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
D Other 3'-5' decay factors
E 112955698 PARN; poly(A)-specific ribonuclease PARN K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]
E 112951986 PNLDC1; poly(A)-specific ribonuclease PNLDC1 isoform X1 K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]
E 112952364 DHX36; ATP-dependent RNA helicase DHX36 K14442 DHX36; ATP-dependent RNA helicase DHX36 [EC:3.6.4.13]
E 112953698 TOB1; protein Tob1 K14443 TOB; protein Tob/BTG
E 112948727 BTG4; protein BTG4 K14443 TOB; protein Tob/BTG
E 112944137 BTG1; protein BTG1 K14443 TOB; protein Tob/BTG
E 112946475 TOB2; protein Tob2 K14443 TOB; protein Tob/BTG
E 112953119 protein BTG1-like K14443 TOB; protein Tob/BTG
E 112959197 BTG2; protein BTG2 K14443 TOB; protein Tob/BTG
E 112950172 NOCT; nocturnin K18764 NOCT; nocturnin [EC:3.1.3.108]
E 112953434 ERI1; 3'-5' exoribonuclease 1 K18416 THEX1; 3'-5' exoribonuclease 1 [EC:3.1.-.-]
E 112959842 ERI2; ERI1 exoribonuclease 2 K18417 ERI2; ERI1 exoribonuclease 2 [EC:3.1.-.-]
E 112947250 DCPS; m7GpppX diphosphatase K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
E 112944067 PDE12; 2',5'-phosphodiesterase 12 K19612 PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-]
E 112946702 IREB2; iron-responsive element-binding protein 2 K22416 IREB2; iron-responsive element-binding protein 2
E 112953769 HELZ; probable helicase with zinc finger domain isoform X1 K25168 HELZ; helicase with zinc finger domain [EC:3.6.4.-]
C Other degradation factors
D RNases
E 112942294 ZC3H12B; probable ribonuclease ZC3H12B K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
E 112943772 ZC3H12C; probable ribonuclease ZC3H12C K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
E 112950822 ZC3H12A; endoribonuclease ZC3H12A K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
#
AProkaryotic type
B Bacterial mRNA degradation factors
C RNA degradosome components
D Ribonucreases
E 112951328 DROSHA; ribonuclease 3 K03685 rnc; ribonuclease III [EC:3.1.26.3]
E 112948079 REXO2; oligoribonuclease, mitochondrial K13288 orn; oligoribonuclease [EC:3.1.-.-]
D Helicases
D Other RNA degradosome components
E 112960082 ENO2; gamma-enolase K01689 ENO; enolase [EC:4.2.1.11]
E 112957010 ENO4; enolase 4 K01689 ENO; enolase [EC:4.2.1.11]
E 112957383 ENO1; alpha-enolase K01689 ENO; enolase [EC:4.2.1.11]
E 112942789 PNPT1; polyribonucleotide nucleotidyltransferase 1, mitochondrial K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
E 112944267 PFKP; ATP-dependent 6-phosphofructokinase, platelet type K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
E 112944865 PFKL; ATP-dependent 6-phosphofructokinase, liver type K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
E 112952237 PFKM; ATP-dependent 6-phosphofructokinase, muscle type isoform X1 K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
C Other RNA degradation factors
D Chaperones
E 112944310 HSPA9; stress-70 protein, mitochondrial K04043 dnaK; molecular chaperone DnaK
E 112955660 HSPD1; 60 kDa heat shock protein, mitochondrial K04077 groEL; chaperonin GroEL
D Others
D Bacterial Small RNA Regulators
B Archeal mRNA degradation factors
C Exosome components
D Core exosome
E 112956109 EXOSC2; exosome complex component RRP4 K03679 RRP4; exosome complex component RRP4
E 112957098 EXOSC1; exosome complex component CSL4 K07573 CSL4; exosome complex component CSL4
D Cofactors
E 112943628 EXOSC7; exosome complex component RRP42 K12589 RRP42; exosome complex component RRP42
D Others
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: February 7, 2022