+E Polyketide biosynthesis proteins KO #

  Polyketide Biosynthesis Proteins - Streptomyces spongiicola

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APolyketide synthase (PKS) B Modular type I PKS C cis-AT PKS D Erythronolide PKS D Oleandomycin synthase D Pikromycin PKS D Avermectin PKS D Tylactone synthase D Protomycinolide IV synthase D Niddamycin PKS D Rapamycin PKS D Immunomycin PKS D Ansamitocin PKS D Rifamycin PKS D Polyene macrolide PKS D Pimaricinolide synthase D Candicidin PKS D Soraphen PKS D Stigmatellin PKS D Mycolactone PKS D Coelimycin PKS D Aureothin PKS D Spectinabilin PKS D Phthiocerol / Phenolphthiocerol PKS C trans-AT PKS D Bacillanene hybrid PKS-NRPS D Chivosazol hybrid PKS-NRPS E ------ chiPKS; chivosazol hybrid polyketide synthase / nonribosomal peptide synthetase [SCL:sce4137 sce4136 sce4135 sce4134 sce4133] D Macrolactin PKS D Difficidin PKS D Rhizoxin hybrid PKS-NRPS D Myxovirescin hybrid PKS-NRPS E ------ taPKS; myxovirescin biosynthesis, hybrid polyketide synthase / nonribosomal peptide synthetase [MXA:MXAN_3935 MXAN_3933 MXAN_3932] D Albicidin synthase, hybrid PKS-NRPS E ------ albXIII; albicidin synthase trans-acting acyltransferase AlbXIII [XAL:XALC_1516] E ------ albPKS; albicidin synthase, hybrid polyketide synthase / nonribosomal peptide synthetase [XAL:XALC_1529 XALC_1532 XALC_1523] D Etnangien PKS E ------ etnPKS; etnangien polyketide synthase [SCL:sce3188 sce3189 sce3190 sce3191 sce3192 sce3193] B Iterative type I PKS C Fungal nonreducing PKS (NR-PKS) C Fungal partially reducing PKS (PR-PKS) C Fungal highly reducing PKS (HR-PKS) C Fungal hybrid type D Zearalenone synthase D Asperfuranone NR/HR-PKS E ------ AFOE; asperfuranone biosynthesis, nonreducing iterative type I polyketide synthase AfoE [ANI:ANIA_01034] E ------ AFOG; asperfuranone biosynthesis, highly reducing iterative type I polyketide synthase AfoG [ANI:ANIA_01036] C Bacterial type B Type II PKS C C9-C14 cyclized polyketide type D Spore pigment PKS E DDQ41_09730 beta-ACP synthase K14667 whiEIII; minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.-] E DDQ41_09735 ketosynthase chain-length factor K14668 whiEIV; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.-] E DDQ41_09740 curamycin polyketide synthase K14669 whiEV; minimal PKS acyl carrier protein E DDQ41_07365 polyketide cyclase K14670 whiEVI; aromatase E DDQ41_09745 polyketide cyclase K14670 whiEVI; aromatase E DDQ41_07340 TcmI family type II polyketide cyclase K14671 whiEVII; cyclase E DDQ41_09750 TcmI family type II polyketide cyclase K14671 whiEVII; cyclase C C7-C14 cyclized polyketide type D Octaketide PKS E DDQ41_07350 beta-ACP synthase K05551 actI1; minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E DDQ41_07355 ketosynthase chain-length factor K05552 actI2; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E DDQ41_07360 acyl carrier protein K05553 actI3; minimal PKS acyl carrier protein D Nonaketide PKS E DDQ41_07350 beta-ACP synthase K05551 actI1; minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E DDQ41_07355 ketosynthase chain-length factor K05552 actI2; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E DDQ41_07360 acyl carrier protein K05553 actI3; minimal PKS acyl carrier protein D Decaketide PKS E DDQ41_07350 beta-ACP synthase K05551 actI1; minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E DDQ41_07355 ketosynthase chain-length factor K05552 actI2; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E DDQ41_07360 acyl carrier protein K05553 actI3; minimal PKS acyl carrier protein B Type III PKS C Plant type C Fungal type C Bacterial type D DDQ41_26490 type III polyketide synthase K19580 rppA; 1,3,6,8-tetrahydroxynaphthalene synthase [EC:2.3.1.233] D ------ arsB; alkylresorcinol synthase [AVN:Avin_29550] D ------ arsC; alkylpyrone synthase [AVN:Avin_29530] B PKS-NRPS hybrid C Bacterial type (modular) D Myxalamid hybrid PKS-NRPS D Myxothiazol hybrid PKS-NRPS E ------ mtaPKS; myxothiazol hybrid polyketide synthase / nonribosomal peptide synthetase [SUR:STAUR_4014 STAUR_4015 STAUR_4016 STAUR_4017 STAUR_4018 STAUR_4019] D Coronatine hybrid PKS-NRPS D Microcystin synthetase D Epothilone synthetase D Bleomycin synthetase D Colibactin synthetase C Fungal type (trans-ER, iterative) D Aspyridone synthetase C Fungal type (iterative) # ANonribosomal peptide synthetase (NRPS) B Linear NRPS C ------ EASA; emericellamide biosynthesis, nonribosomal peptide synthetase EasA [ANI:ANIA_02545] C ------ lgrABCD; linear pentadecapeptide gramicidin synthetase [BBE:BBR47_28920 BBR47_28930 BBR47_28940 BBR47_29500] C ------ mcnABCE; cyanopeptolin synthetase [MAR:MAE_60030 MAE_60020 MAE_60010 MAE_60000] C ACV synthetase C Bacitracin synthetase C Viomycin synthetase C Pristinamycin I synthetase C Tyrocidine synthetase C Surfactin family lipopeptide synthetase C Iturin family lipopeptide synthetase C Fengycin family lipopeptide synthetase C Arthrofactin type cyclic lipopeptide synthetase C Vancomycin synthetase C Nocardicin synthetase D DDQ41_16145 antibiotic synthesis protein MbtH K05375 mbtH; MbtH protein D DDQ41_25575 MbtH family protein K05375 mbtH; MbtH protein C Bialaphos synthetase C L-2-amino-4-methoxy-trans-3-butenoic acid synthetase B Iterative NRPS C Enterobactin synthetase D DDQ41_28735 4'-phosphopantetheinyl transferase K02362 entD; enterobactin synthetase component D / holo-[acyl-carrier protein] synthase [EC:6.3.2.14 2.7.8.7] D DDQ41_25540 2,3-dihydroxybenzoate-AMP ligase K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] C Bacillibactin synthetase D DDQ41_25540 2,3-dihydroxybenzoate-AMP ligase K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] C Gramicidin synthetase B Nonlinear NRPS C Yersiniabactin synthetase C Pyochelin synthetase C Mycobactin synthetase C Vibriobactin synthetase D DDQ41_25540 2,3-dihydroxybenzoate-AMP ligase K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] C Myxochelin synthetase D DDQ41_25540 2,3-dihydroxybenzoate-AMP ligase K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] C Petrobacin synthetase C Syringomycin synthetase C Vanchrobactin synthetase D DDQ41_25540 2,3-dihydroxybenzoate-AMP ligase K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] # APolyketide tailoring proteins B Hydrolase C DDQ41_30995 4-hydroxybenzoyl-CoA thioesterase K15315 sgcE10; enediyne core biosynthesis thioesterase B Ketoreductase B Oxygenase C DDQ41_00860 cytochrome P450 K20420 ncsB3; 2-hydroxy-5-methyl-1-naphthoate 7-hydroxylase [EC:1.14.15.31] C DDQ41_21455 cytochrome P450 K20420 ncsB3; 2-hydroxy-5-methyl-1-naphthoate 7-hydroxylase [EC:1.14.15.31] C DDQ41_30005 cytochrome P450 K20420 ncsB3; 2-hydroxy-5-methyl-1-naphthoate 7-hydroxylase [EC:1.14.15.31] C DDQ41_30940 cytochrome P450 K20420 ncsB3; 2-hydroxy-5-methyl-1-naphthoate 7-hydroxylase [EC:1.14.15.31] C DDQ41_30925 Pyoverdin chromophore biosynthetic protein pvcC K21184 sgcC; two-component FAD-dependent monooxygenase [EC:1.14.14.15 1.14.14.-] C DDQ41_30650 hydrolase K21159 sgcF; epoxide hydrolase C DDQ41_07345 cupin domain-containing protein K14673 whiEII; putative monooxygenase C DDQ41_09725 protein in whiE locus K14673 whiEII; putative monooxygenase C DDQ41_09715 monooxygenase K14672 whiEVIII; putative polyketide hydroxylase B Methylase C DDQ41_09755 methyltransferase K14251 oxyF; C-methyltransferase [EC:2.1.1.-] B Glycosyltransferase B Halogenase B beta-Branched incorporating proteins B Others C DDQ41_28830 cyclodehydratase K14627 actVI3; dehydratase [EC:4.2.1.-] C DDQ41_31030 enediyne biosynthesis protein K21160 sgcE2; enediyne biosynthesis protein E2 C DDQ41_31025 enediyne biosynthesis protein K21161 sgcE3; enediyne biosynthesis protein E3 C DDQ41_31020 RNA-binding protein K21162 sgcE4; enediyne biosynthesis protein E4 C DDQ41_31015 enediyne biosynthesis protein K21163 sgcE5; enediyne biosynthesis protein E5 C DDQ41_30985 cytochrome P450 K21164 sgcE7; enediyne biosynthesis protein E7 C DDQ41_30970 regulator K21165 sgcE8; enediyne biosynthesis protein E8 C DDQ41_30965 glucose-methanol-choline oxidoreductase K21166 sgcE9; enediyne biosynthesis protein E9 C DDQ41_30960 TIGR03084 family protein K21167 sgcE11; enediyne biosynthesis protein E11 C DDQ41_30920 hypothetical protein K21186 sgcC5; condensation enzyme C DDQ41_30990 flavin reductase K21185 sgcE6; flavin reductase # ANonribosomal peptide tailoring proteins B Reductase B Thioesterase B Oxygenase B Glycosyltransferase B Aminotransferase B Others C DDQ41_20935 aspartate racemase K01779 racD; aspartate racemase [EC:5.1.1.13] ! #
#[ COMPOUND | BRITE | KEGG2 | KEGG ]
#Last updated: June 19, 2024