+E Enzyme KO #

  Enzymes - Yersinia rochesterensis

% ! A1. Oxidoreductases B 1.1 Acting on the CH-OH group of donors C 1.1.1 With NAD+ or NADP+ as acceptor D 1.1.1.1 alcohol dehydrogenase E CH54_1031 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1] E CH54_551 aldehyde dehydrogenase family protein K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] D 1.1.1.2 alcohol dehydrogenase (NADP+) E CH54_3064 zinc-binding dehydrogenase family protein K13979 yahK; alcohol dehydrogenase (NADP+) [EC:1.1.1.2] D 1.1.1.3 homoserine dehydrogenase E CH54_1848 aspartate kinase domain protein K12524 thrA; bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3] E CH54_2693 aspartate kinase domain protein K12525 metL; bifunctional aspartokinase / homoserine dehydrogenase 2 [EC:2.7.2.4 1.1.1.3] D 1.1.1.4 (R,R)-butanediol dehydrogenase D 1.1.1.6 glycerol dehydrogenase E CH54_1894 iron-containing alcohol dehydrogenase family protein K00005 gldA; glycerol dehydrogenase [EC:1.1.1.6] D 1.1.1.7 propanediol-phosphate dehydrogenase D 1.1.1.8 glycerol-3-phosphate dehydrogenase (NAD+) D 1.1.1.9 D-xylulose reductase D 1.1.1.10 L-xylulose reductase D 1.1.1.11 D-arabinitol 4-dehydrogenase D 1.1.1.12 L-arabinitol 4-dehydrogenase D 1.1.1.13 L-arabinitol 2-dehydrogenase D 1.1.1.14 L-iditol 2-dehydrogenase D 1.1.1.15 D-iditol 2-dehydrogenase D 1.1.1.16 galactitol 2-dehydrogenase D 1.1.1.17 mannitol-1-phosphate 5-dehydrogenase E CH54_2468 mannitol dehydrogenase Rossmann domain protein K00009 mtlD; mannitol-1-phosphate 5-dehydrogenase [EC:1.1.1.17] D 1.1.1.18 inositol 2-dehydrogenase E CH54_2365 hypothetical protein K00010 iolG; myo-inositol 2-dehydrogenase / D-chiro-inositol 1-dehydrogenase [EC:1.1.1.18 1.1.1.369] D 1.1.1.19 glucuronate reductase D 1.1.1.20 glucuronolactone reductase D 1.1.1.21 aldose reductase D 1.1.1.22 UDP-glucose 6-dehydrogenase E CH54_556 nucleotide sugar dehydrogenase family protein K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22] D 1.1.1.23 histidinol dehydrogenase E CH54_979 hisD; histidinol dehydrogenase K00013 hisD; histidinol dehydrogenase [EC:1.1.1.23] D 1.1.1.24 quinate/shikimate dehydrogenase (NAD+) D 1.1.1.25 shikimate dehydrogenase (NADP+) E CH54_2214 aroE; shikimate dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25] D 1.1.1.26 glyoxylate reductase D 1.1.1.27 L-lactate dehydrogenase D 1.1.1.28 D-lactate dehydrogenase E CH54_360 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein K03778 ldhA; D-lactate dehydrogenase [EC:1.1.1.28] D 1.1.1.29 glycerate dehydrogenase D 1.1.1.30 3-hydroxybutyrate dehydrogenase D 1.1.1.31 3-hydroxyisobutyrate dehydrogenase D 1.1.1.34 hydroxymethylglutaryl-CoA reductase (NADPH) D 1.1.1.35 3-hydroxyacyl-CoA dehydrogenase E CH54_3859 fadJ; fatty oxidation complex, alpha subunit FadJ K01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3] E CH54_2852 fadB; fatty oxidation complex, alpha subunit FadB K01825 fadB; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase [EC:1.1.1.35 4.2.1.17 5.1.2.3 5.3.3.8] D 1.1.1.36 acetoacetyl-CoA reductase D 1.1.1.37 malate dehydrogenase E CH54_2000 mdh; malate dehydrogenase, NAD-dependent K00024 mdh; malate dehydrogenase [EC:1.1.1.37] D 1.1.1.38 malate dehydrogenase (oxaloacetate-decarboxylating) E CH54_1004 malic enzyme, NAD binding domain protein K00027 ME2; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38] D 1.1.1.39 malate dehydrogenase (decarboxylating) D 1.1.1.40 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) E CH54_1317 malic enzyme, NAD binding domain protein K00029 maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40] D 1.1.1.41 isocitrate dehydrogenase (NAD+) D 1.1.1.42 isocitrate dehydrogenase (NADP+) E CH54_119 icd; isocitrate dehydrogenase, NADP-dependent K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42] D 1.1.1.43 phosphogluconate 2-dehydrogenase D 1.1.1.44 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) E CH54_986 gnd; 6-phosphogluconate dehydrogenase K00033 PGD; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343] D 1.1.1.45 L-gulonate 3-dehydrogenase D 1.1.1.46 L-arabinose 1-dehydrogenase D 1.1.1.47 glucose 1-dehydrogenase [NAD(P)+] D 1.1.1.48 D-galactose 1-dehydrogenase D 1.1.1.49 glucose-6-phosphate dehydrogenase (NADP+) E CH54_612 zwf; glucose-6-phosphate dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363] D 1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) D 1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase D 1.1.1.52 3alpha-hydroxycholanate dehydrogenase (NAD+) D 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase D 1.1.1.54 allyl-alcohol dehydrogenase D 1.1.1.55 lactaldehyde reductase (NADPH) D 1.1.1.56 ribitol 2-dehydrogenase D 1.1.1.57 fructuronate reductase E CH54_4005 mannitol dehydrogenase Rossmann domain protein K00040 uxuB; fructuronate reductase [EC:1.1.1.57] D 1.1.1.58 tagaturonate reductase E CH54_3079 mannitol dehydrogenase Rossmann domain protein K00041 uxaB; tagaturonate reductase [EC:1.1.1.58] D 1.1.1.59 3-hydroxypropionate dehydrogenase D 1.1.1.60 2-hydroxy-3-oxopropionate reductase E CH54_2078 2-hydroxy-3-oxopropionate reductase K00042 garR; 2-hydroxy-3-oxopropionate reductase [EC:1.1.1.60] D 1.1.1.61 4-hydroxybutyrate dehydrogenase D 1.1.1.62 17beta-estradiol 17-dehydrogenase D 1.1.1.64 testosterone 17beta-dehydrogenase (NADP+) D 1.1.1.65 pyridoxine 4-dehydrogenase D 1.1.1.66 omega-hydroxydecanoate dehydrogenase D 1.1.1.67 mannitol 2-dehydrogenase D 1.1.1.69 gluconate 5-dehydrogenase E CH54_3942 short chain dehydrogenase family protein K00046 idnO; gluconate 5-dehydrogenase [EC:1.1.1.69] D 1.1.1.71 alcohol dehydrogenase [NAD(P)+] D 1.1.1.72 glycerol dehydrogenase (NADP+) D 1.1.1.73 octanol dehydrogenase D 1.1.1.75 (R)-aminopropanol dehydrogenase D 1.1.1.76 (S,S)-butanediol dehydrogenase D 1.1.1.77 lactaldehyde reductase D 1.1.1.78 methylglyoxal reductase (NADH) D 1.1.1.79 glyoxylate reductase (NADP+) E CH54_2481 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein K00090 ghrB; glyoxylate/hydroxypyruvate/2-ketogluconate reductase [EC:1.1.1.79 1.1.1.81 1.1.1.215] E CH54_644 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein K12972 ghrA; glyoxylate/hydroxypyruvate reductase [EC:1.1.1.79 1.1.1.81] D 1.1.1.80 isopropanol dehydrogenase (NADP+) D 1.1.1.81 hydroxypyruvate reductase E CH54_2481 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein K00090 ghrB; glyoxylate/hydroxypyruvate/2-ketogluconate reductase [EC:1.1.1.79 1.1.1.81 1.1.1.215] E CH54_644 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein K12972 ghrA; glyoxylate/hydroxypyruvate reductase [EC:1.1.1.79 1.1.1.81] D 1.1.1.82 malate dehydrogenase (NADP+) D 1.1.1.83 D-malate dehydrogenase (decarboxylating) D 1.1.1.84 dimethylmalate dehydrogenase D 1.1.1.85 3-isopropylmalate dehydrogenase E CH54_1797 leuB; 3-isopropylmalate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85] D 1.1.1.86 ketol-acid reductoisomerase (NADP+) E CH54_2733 ilvC; ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] D 1.1.1.87 homoisocitrate dehydrogenase D 1.1.1.88 hydroxymethylglutaryl-CoA reductase D 1.1.1.90 aryl-alcohol dehydrogenase D 1.1.1.91 aryl-alcohol dehydrogenase (NADP+) D 1.1.1.92 oxaloglycolate reductase (decarboxylating) D 1.1.1.93 tartrate dehydrogenase D 1.1.1.94 glycerol-3-phosphate dehydrogenase [NAD(P)+] E CH54_2663 ketopantoate reductase PanE/ApbA family protein K00057 gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94] D 1.1.1.95 phosphoglycerate dehydrogenase E CH54_3399 ACT domain protein K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D 1.1.1.96 diiodophenylpyruvate reductase D 1.1.1.97 3-hydroxybenzyl-alcohol dehydrogenase D 1.1.1.98 (R)-2-hydroxy-fatty-acid dehydrogenase D 1.1.1.99 (S)-2-hydroxy-fatty-acid dehydrogenase D 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase E CH54_387 short chain dehydrogenase family protein K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] E CH54_78 fabG; 3-oxoacyl-[acyl-carrier-protein] reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] E CH54_1658 short chain dehydrogenase family protein K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] D 1.1.1.101 acylglycerone-phosphate reductase D 1.1.1.102 3-dehydrosphinganine reductase D 1.1.1.103 L-threonine 3-dehydrogenase E CH54_2656 tdh; L-threonine 3-dehydrogenase K00060 tdh; threonine 3-dehydrogenase [EC:1.1.1.103] D 1.1.1.104 4-oxoproline reductase D 1.1.1.105 all-trans-retinol dehydrogenase (NAD+) D 1.1.1.106 pantoate 4-dehydrogenase D 1.1.1.107 pyridoxal 4-dehydrogenase D 1.1.1.108 carnitine 3-dehydrogenase D 1.1.1.110 aromatic 2-oxoacid reductase D 1.1.1.111 3-(imidazol-5-yl)lactate dehydrogenase D 1.1.1.112 indanol dehydrogenase D 1.1.1.113 L-xylose 1-dehydrogenase D 1.1.1.114 apiose 1-reductase D 1.1.1.115 ribose 1-dehydrogenase (NADP+) D 1.1.1.116 D-arabinose 1-dehydrogenase (NAD+) D 1.1.1.117 D-arabinose 1-dehydrogenase [NAD(P)+] D 1.1.1.118 glucose 1-dehydrogenase (NAD+) D 1.1.1.119 glucose 1-dehydrogenase (NADP+) D 1.1.1.120 galactose 1-dehydrogenase (NADP+) D 1.1.1.121 aldose 1-dehydrogenase (NAD+) D 1.1.1.122 D-threo-aldose 1-dehydrogenase D 1.1.1.123 sorbose 5-dehydrogenase (NADP+) D 1.1.1.124 fructose 5-dehydrogenase (NADP+) D 1.1.1.125 2-deoxy-D-gluconate 3-dehydrogenase D 1.1.1.126 2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase D 1.1.1.127 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase E CH54_232 kduD; 2-deoxy-D-gluconate 3-dehydrogenase K00065 kduD; 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase [EC:1.1.1.127] D 1.1.1.129 L-threonate 3-dehydrogenase D 1.1.1.130 3-dehydro-L-gulonate 2-dehydrogenase D 1.1.1.131 mannuronate reductase D 1.1.1.132 GDP-mannose 6-dehydrogenase D 1.1.1.133 dTDP-4-dehydrorhamnose reductase D 1.1.1.134 dTDP-6-deoxy-L-talose 4-dehydrogenase (NADP+) D 1.1.1.135 GDP-6-deoxy-D-talose 4-dehydrogenase D 1.1.1.136 UDP-N-acetylglucosamine 6-dehydrogenase D 1.1.1.137 ribitol-5-phosphate 2-dehydrogenase D 1.1.1.138 mannitol 2-dehydrogenase (NADP+) D 1.1.1.140 sorbitol-6-phosphate 2-dehydrogenase E CH54_1379 short chain dehydrogenase family protein K00068 srlD; sorbitol-6-phosphate 2-dehydrogenase [EC:1.1.1.140] E CH54_1647 3-beta hydroxysteroid dehydrogenase/isomerase family protein K00068 srlD; sorbitol-6-phosphate 2-dehydrogenase [EC:1.1.1.140] D 1.1.1.141 15-hydroxyprostaglandin dehydrogenase (NAD+) D 1.1.1.142 D-pinitol dehydrogenase D 1.1.1.143 sequoyitol dehydrogenase D 1.1.1.144 perillyl-alcohol dehydrogenase D 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase D 1.1.1.146 11beta-hydroxysteroid dehydrogenase D 1.1.1.147 16alpha-hydroxysteroid dehydrogenase D 1.1.1.148 estradiol 17alpha-dehydrogenase D 1.1.1.149 20alpha-hydroxysteroid dehydrogenase D 1.1.1.150 21-hydroxysteroid dehydrogenase (NAD+) D 1.1.1.151 21-hydroxysteroid dehydrogenase (NADP+) D 1.1.1.152 3alpha-hydroxy-5beta-androstane-17-one 3alpha-dehydrogenase D 1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming) D 1.1.1.154 ureidoglycolate dehydrogenase D 1.1.1.156 glycerol 2-dehydrogenase (NADP+) D 1.1.1.157 3-hydroxybutyryl-CoA dehydrogenase D 1.1.1.159 7alpha-hydroxysteroid dehydrogenase D 1.1.1.160 dihydrobunolol dehydrogenase D 1.1.1.162 erythrulose reductase D 1.1.1.163 cyclopentanol dehydrogenase D 1.1.1.164 hexadecanol dehydrogenase D 1.1.1.165 2-alkyn-1-ol dehydrogenase D 1.1.1.166 hydroxycyclohexanecarboxylate dehydrogenase D 1.1.1.167 hydroxymalonate dehydrogenase D 1.1.1.168 2-dehydropantolactone reductase (Re-specific) D 1.1.1.169 2-dehydropantoate 2-reductase E CH54_3673 2-dehydropantoate 2-reductase family protein K00077 panE; 2-dehydropantoate 2-reductase [EC:1.1.1.169] D 1.1.1.170 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating) D 1.1.1.172 2-oxoadipate reductase D 1.1.1.173 L-rhamnose 1-dehydrogenase D 1.1.1.174 cyclohexane-1,2-diol dehydrogenase D 1.1.1.175 D-xylose 1-dehydrogenase D 1.1.1.176 12alpha-hydroxysteroid dehydrogenase D 1.1.1.177 glycerol-3-phosphate 1-dehydrogenase (NADP+) D 1.1.1.178 3-hydroxy-2-methylbutyryl-CoA dehydrogenase D 1.1.1.179 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming) D 1.1.1.181 cholest-5-ene-3beta,7alpha-diol 3beta-dehydrogenase D 1.1.1.183 geraniol dehydrogenase (NADP+) D 1.1.1.184 carbonyl reductase (NADPH) D 1.1.1.185 L-glycol dehydrogenase D 1.1.1.186 dTDP-galactose 6-dehydrogenase D 1.1.1.187 GDP-4-dehydro-D-rhamnose reductase D 1.1.1.188 prostaglandin-F synthase D 1.1.1.189 prostaglandin-E2 9-reductase D 1.1.1.190 indole-3-acetaldehyde reductase (NADH) D 1.1.1.191 indole-3-acetaldehyde reductase (NADPH) D 1.1.1.192 long-chain-alcohol dehydrogenase D 1.1.1.193 5-amino-6-(5-phosphoribosylamino)uracil reductase E CH54_3663 ribD; riboflavin biosynthesis protein RibD K11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193] D 1.1.1.194 coniferyl-alcohol dehydrogenase D 1.1.1.195 cinnamyl-alcohol dehydrogenase D 1.1.1.196 15-hydroxyprostaglandin-D dehydrogenase (NADP+) D 1.1.1.197 15-hydroxyprostaglandin dehydrogenase (NADP+) D 1.1.1.198 (+)-borneol dehydrogenase D 1.1.1.199 (S)-usnate reductase D 1.1.1.200 aldose-6-phosphate reductase (NADPH) D 1.1.1.201 7beta-hydroxysteroid dehydrogenase (NADP+) D 1.1.1.202 1,3-propanediol dehydrogenase D 1.1.1.203 uronate dehydrogenase D 1.1.1.205 IMP dehydrogenase E CH54_1441 guaB; inosine-5'-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205] D 1.1.1.206 tropinone reductase I D 1.1.1.207 (-)-menthol dehydrogenase D 1.1.1.208 (+)-neomenthol dehydrogenase D 1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase D 1.1.1.210 3beta(or 20alpha)-hydroxysteroid dehydrogenase D 1.1.1.211 long-chain-3-hydroxyacyl-CoA dehydrogenase D 1.1.1.212 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) D 1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific) D 1.1.1.214 2-dehydropantolactone reductase (Si-specific) D 1.1.1.215 gluconate 2-dehydrogenase E CH54_2481 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein K00090 ghrB; glyoxylate/hydroxypyruvate/2-ketogluconate reductase [EC:1.1.1.79 1.1.1.81 1.1.1.215] D 1.1.1.216 farnesol dehydrogenase (NADP+) D 1.1.1.217 benzyl-2-methyl-hydroxybutyrate dehydrogenase D 1.1.1.218 morphine 6-dehydrogenase D 1.1.1.219 dihydroflavonol 4-reductase D 1.1.1.220 6-pyruvoyltetrahydropterin 2'-reductase D 1.1.1.221 vomifoliol dehydrogenase D 1.1.1.223 isopiperitenol dehydrogenase D 1.1.1.224 mannose-6-phosphate 6-reductase D 1.1.1.225 chlordecone reductase D 1.1.1.226 4-hydroxycyclohexanecarboxylate dehydrogenase D 1.1.1.227 (-)-borneol dehydrogenase D 1.1.1.228 (+)-sabinol dehydrogenase D 1.1.1.229 diethyl 2-methyl-3-oxosuccinate reductase D 1.1.1.230 3alpha-hydroxyglycyrrhetinate dehydrogenase D 1.1.1.231 15-hydroxyprostaglandin-I dehydrogenase (NADP+) D 1.1.1.232 15-hydroxyicosatetraenoate dehydrogenase D 1.1.1.233 N-acylmannosamine 1-dehydrogenase D 1.1.1.234 flavanone 4-reductase D 1.1.1.235 8-oxocoformycin reductase D 1.1.1.236 tropinone reductase II D 1.1.1.237 hydroxyphenylpyruvate reductase D 1.1.1.238 12beta-hydroxysteroid dehydrogenase D 1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) D 1.1.1.240 N-acetylhexosamine 1-dehydrogenase D 1.1.1.241 6-endo-hydroxycineole dehydrogenase D 1.1.1.243 carveol dehydrogenase D 1.1.1.244 methanol dehydrogenase D 1.1.1.245 cyclohexanol dehydrogenase D 1.1.1.247 codeinone reductase (NADPH) D 1.1.1.248 salutaridine reductase (NADPH) D 1.1.1.250 D-arabinitol 2-dehydrogenase D 1.1.1.251 galactitol-1-phosphate 5-dehydrogenase D 1.1.1.252 tetrahydroxynaphthalene reductase D 1.1.1.254 (S)-carnitine 3-dehydrogenase D 1.1.1.255 mannitol dehydrogenase D 1.1.1.256 fluoren-9-ol dehydrogenase D 1.1.1.257 4-(hydroxymethyl)benzenesulfonate dehydrogenase D 1.1.1.258 6-hydroxyhexanoate dehydrogenase D 1.1.1.259 3-hydroxypimeloyl-CoA dehydrogenase D 1.1.1.260 sulcatone reductase D 1.1.1.261 sn-glycerol-1-phosphate dehydrogenase D 1.1.1.262 4-hydroxythreonine-4-phosphate dehydrogenase E CH54_1816 pdxA; 4-hydroxythreonine-4-phosphate dehydrogenase PdxA K00097 pdxA; 4-hydroxythreonine-4-phosphate dehydrogenase [EC:1.1.1.262] D 1.1.1.263 1,5-anhydro-D-fructose reductase D 1.1.1.264 L-idonate 5-dehydrogenase D 1.1.1.265 3-methylbutanal reductase D 1.1.1.266 dTDP-4-dehydro-6-deoxyglucose reductase D 1.1.1.267 1-deoxy-D-xylulose-5-phosphate reductoisomerase E CH54_3524 dxr; 1-deoxy-D-xylulose 5-phosphate reductoisomerase K00099 dxr; 1-deoxy-D-xylulose-5-phosphate reductoisomerase [EC:1.1.1.267] D 1.1.1.268 2-(R)-hydroxypropyl-CoM dehydrogenase D 1.1.1.269 2-(S)-hydroxypropyl-CoM dehydrogenase D 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase D 1.1.1.271 GDP-L-fucose synthase D 1.1.1.272 D-2-hydroxyacid dehydrogenase (NADP+) D 1.1.1.273 vellosimine dehydrogenase D 1.1.1.274 2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming) D 1.1.1.275 (+)-trans-carveol dehydrogenase D 1.1.1.276 serine 3-dehydrogenase (NADP+) D 1.1.1.277 3beta-hydroxy-5beta-steroid dehydrogenase D 1.1.1.278 3beta-hydroxy-5alpha-steroid dehydrogenase D 1.1.1.279 (R)-3-hydroxyacid-ester dehydrogenase D 1.1.1.280 (S)-3-hydroxyacid-ester dehydrogenase D 1.1.1.281 GDP-4-dehydro-6-deoxy-D-mannose reductase D 1.1.1.282 quinate/shikimate dehydrogenase [NAD(P)+] D 1.1.1.283 methylglyoxal reductase (NADPH) D 1.1.1.284 S-(hydroxymethyl)glutathione dehydrogenase E CH54_1031 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1] D 1.1.1.285 3''-deamino-3''-oxonicotianamine reductase D 1.1.1.286 isocitrate---homoisocitrate dehydrogenase D 1.1.1.287 D-arabinitol dehydrogenase (NADP+) D 1.1.1.288 xanthoxin dehydrogenase D 1.1.1.289 sorbose reductase D 1.1.1.290 4-phosphoerythronate dehydrogenase E CH54_3888 hypothetical protein K03473 pdxB; erythronate-4-phosphate dehydrogenase [EC:1.1.1.290] D 1.1.1.291 2-hydroxymethylglutarate dehydrogenase D 1.1.1.292 1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming) D 1.1.1.294 chlorophyll(ide) b reductase D 1.1.1.295 momilactone-A synthase D 1.1.1.296 dihydrocarveol dehydrogenase D 1.1.1.297 limonene-1,2-diol dehydrogenase D 1.1.1.298 3-hydroxypropionate dehydrogenase (NADP+) D 1.1.1.299 malate dehydrogenase [NAD(P)+] D 1.1.1.300 NADP-retinol dehydrogenase D 1.1.1.301 D-arabitol-phosphate dehydrogenase D 1.1.1.302 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase D 1.1.1.303 diacetyl reductase [(R)-acetoin forming] D 1.1.1.304 diacetyl reductase [(S)-acetoin forming] D 1.1.1.305 UDP-glucuronic acid dehydrogenase (UDP-4-keto-hexauronic acid decarboxylating) E CH54_266 3-beta hydroxysteroid dehydrogenase/isomerase family protein K10011 arnA; UDP-4-amino-4-deoxy-L-arabinose formyltransferase / UDP-glucuronic acid dehydrogenase (UDP-4-keto-hexauronic acid decarboxylating) [EC:2.1.2.13 1.1.1.305] D 1.1.1.306 S-(hydroxymethyl)mycothiol dehydrogenase D 1.1.1.307 D-xylose reductase [NAD(P)H] D 1.1.1.308 sulfopropanediol 3-dehydrogenase D 1.1.1.309 phosphonoacetaldehyde reductase (NADH) D 1.1.1.310 (S)-sulfolactate dehydrogenase D 1.1.1.311 (S)-1-phenylethanol dehydrogenase D 1.1.1.312 2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase D 1.1.1.313 sulfoacetaldehyde reductase (NADPH) D 1.1.1.315 11-cis-retinol dehydrogenase D 1.1.1.316 L-galactose 1-dehydrogenase D 1.1.1.317 perakine reductase D 1.1.1.318 eugenol synthase D 1.1.1.319 isoeugenol synthase D 1.1.1.320 benzil reductase [(S)-benzoin forming] D 1.1.1.321 benzil reductase [(R)-benzoin forming] D 1.1.1.322 (-)-endo-fenchol dehydrogenase D 1.1.1.323 (+)-thujan-3-ol dehydrogenase D 1.1.1.324 8-hydroxygeraniol dehydrogenase D 1.1.1.325 sepiapterin reductase (L-threo-7,8-dihydrobiopterin forming) D 1.1.1.326 zerumbone synthase D 1.1.1.327 5-exo-hydroxycamphor dehydrogenase D 1.1.1.328 nicotine blue oxidoreductase D 1.1.1.329 2-deoxy-scyllo-inosamine dehydrogenase D 1.1.1.330 very-long-chain 3-oxoacyl-CoA reductase D 1.1.1.331 secoisolariciresinol dehydrogenase D 1.1.1.332 chanoclavine-I dehydrogenase D 1.1.1.333 decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose 2-reductase D 1.1.1.334 methylecgonone reductase D 1.1.1.335 UDP-N-acetyl-2-amino-2-deoxyglucuronate dehydrogenase D 1.1.1.336 UDP-N-acetyl-D-mannosamine dehydrogenase E CH54_2753 nucleotide sugar dehydrogenase family protein K02472 wecC; UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase [EC:1.1.1.336] D 1.1.1.337 L-2-hydroxycarboxylate dehydrogenase (NAD+) D 1.1.1.338 (2R)-3-sulfolactate dehydrogenase (NADP+) D 1.1.1.339 dTDP-6-deoxy-L-talose 4-dehydrogenase (NAD+) D 1.1.1.340 1-deoxy-11beta-hydroxypentalenate dehydrogenase D 1.1.1.341 CDP-abequose synthase D 1.1.1.342 CDP-paratose synthase D 1.1.1.343 phosphogluconate dehydrogenase (NAD+-dependent, decarboxylating) E CH54_986 gnd; 6-phosphogluconate dehydrogenase K00033 PGD; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343] D 1.1.1.344 dTDP-6-deoxy-L-talose 4-dehydrogenase [NAD(P)+] D 1.1.1.345 D-2-hydroxyacid dehydrogenase (NAD+) D 1.1.1.346 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming) E CH54_3134 aldo/keto reductase family protein K06221 dkgA; 2,5-diketo-D-gluconate reductase A [EC:1.1.1.346] E CH54_3298 aldo/keto reductase family protein K06221 dkgA; 2,5-diketo-D-gluconate reductase A [EC:1.1.1.346] E CH54_1594 aldo/keto reductase family protein K06222 dkgB; 2,5-diketo-D-gluconate reductase B [EC:1.1.1.346] D 1.1.1.347 geraniol dehydrogenase (NAD+) D 1.1.1.348 (3R)-2'-hydroxyisoflavanone reductase D 1.1.1.349 norsolorinic acid ketoreductase D 1.1.1.350 ureidoglycolate dehydrogenase (NAD+) D 1.1.1.351 phosphogluconate dehydrogenase [NAD(P)+-dependent, decarboxylating] D 1.1.1.352 5'-hydroxyaverantin dehydrogenase D 1.1.1.353 versiconal hemiacetal acetate reductase D 1.1.1.354 farnesol dehydrogenase (NAD+) D 1.1.1.355 2'-dehydrokanamycin reductase D 1.1.1.356 GDP-L-colitose synthase D 1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase D 1.1.1.358 2-dehydropantolactone reductase D 1.1.1.359 aldose 1-dehydrogenase [NAD(P)+] D 1.1.1.360 glucose/galactose 1-dehydrogenase D 1.1.1.361 glucose-6-phosphate 3-dehydrogenase D 1.1.1.362 aklaviketone reductase D 1.1.1.363 glucose-6-phosphate dehydrogenase [NAD(P)+] E CH54_612 zwf; glucose-6-phosphate dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363] D 1.1.1.364 dTDP-4-dehydro-6-deoxy-alpha-D-gulose 4-ketoreductase D 1.1.1.365 D-galacturonate reductase D 1.1.1.366 L-idonate 5-dehydrogenase (NAD+) D 1.1.1.367 UDP-2-acetamido-2,6-beta-L-arabino-hexul-4-ose reductase E CH54_3602 rmlD substrate binding domain protein K19068 wbjC; UDP-2-acetamido-2,6-beta-L-arabino-hexul-4-ose reductase [EC:1.1.1.367] D 1.1.1.368 6-hydroxycyclohex-1-ene-1-carbonyl-CoA dehydrogenase D 1.1.1.369 D-chiro-inositol 1-dehydrogenase E CH54_2365 hypothetical protein K00010 iolG; myo-inositol 2-dehydrogenase / D-chiro-inositol 1-dehydrogenase [EC:1.1.1.18 1.1.1.369] D 1.1.1.370 scyllo-inositol 2-dehydrogenase (NAD+) D 1.1.1.371 scyllo-inositol 2-dehydrogenase (NADP+) D 1.1.1.372 D/L-glyceraldehyde reductase D 1.1.1.373 sulfolactaldehyde 3-reductase D 1.1.1.374 UDP-N-acetylglucosamine 3-dehydrogenase D 1.1.1.375 L-2-hydroxycarboxylate dehydrogenase [NAD(P)+] D 1.1.1.376 L-arabinose 1-dehydrogenase [NAD(P)+] D 1.1.1.377 L-rhamnose 1-dehydrogenase (NADP+) D 1.1.1.378 L-rhamnose 1-dehydrogenase [NAD(P)+] D 1.1.1.379 (R)-mandelate dehydrogenase D 1.1.1.380 L-gulonate 5-dehydrogenase D 1.1.1.381 3-hydroxy acid dehydrogenase E CH54_428 polysaccharide biosynthesis family protein K16066 ydfG; 3-hydroxy acid dehydrogenase / malonic semialdehyde reductase [EC:1.1.1.381 1.1.1.-] D 1.1.1.382 ketol-acid reductoisomerase (NAD+) D 1.1.1.383 ketol-acid reductoisomerase [NAD(P)+] D 1.1.1.384 dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase D 1.1.1.385 dihydroanticapsin dehydrogenase D 1.1.1.386 ipsdienol dehydrogenase D 1.1.1.387 L-serine 3-dehydrogenase (NAD+) D 1.1.1.388 glucose-6-phosphate dehydrogenase (NAD+) D 1.1.1.389 2-dehydro-3-deoxy-L-galactonate 5-dehydrogenase D 1.1.1.390 sulfoquinovose 1-dehydrogenase D 1.1.1.391 3beta-hydroxycholanate 3-dehydrogenase (NAD+) D 1.1.1.392 3alpha-hydroxycholanate dehydrogenase (NADP+) D 1.1.1.393 3beta-hydroxycholanate 3-dehydrogenase (NADP+) D 1.1.1.394 aurachin B dehydrogenase D 1.1.1.395 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase D 1.1.1.396 bacteriochlorophyllide a dehydrogenase D 1.1.1.397 beta-methylindole-3-pyruvate reductase D 1.1.1.398 2-glutathionyl-2-methylbut-3-en-1-ol dehydrogenase D 1.1.1.399 2-oxoglutarate reductase E CH54_3399 ACT domain protein K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] D 1.1.1.400 2-methyl-1,2-propanediol dehydrogenase D 1.1.1.401 2-dehydro-3-deoxy-L-rhamnonate dehydrogenase (NAD+) D 1.1.1.402 D-erythritol 1-phosphate dehydrogenase D 1.1.1.403 D-threitol dehydrogenase (NAD+) D 1.1.1.404 tetrachlorobenzoquinone reductase D 1.1.1.405 ribitol-5-phosphate 2-dehydrogenase (NADP+) D 1.1.1.406 galactitol 2-dehydrogenase (L-tagatose-forming) D 1.1.1.407 D-altritol 5-dehydrogenase D 1.1.1.408 4-phospho-D-threonate 3-dehydrogenase D 1.1.1.409 4-phospho-D-erythronate 3-dehydrogenase D 1.1.1.410 D-erythronate 2-dehydrogenase E CH54_3176 3-beta hydroxysteroid dehydrogenase/isomerase family protein K22025 denD; D-erythronate 2-dehydrogenase [EC:1.1.1.410] D 1.1.1.411 L-threonate 2-dehydrogenase D 1.1.1.412 2-alkyl-3-oxoalkanoate reductase D 1.1.1.413 A-factor type gamma-butyrolactone 1'-reductase (1S-forming) D 1.1.1.414 L-galactonate 5-dehydrogenase D 1.1.1.415 noscapine synthase D 1.1.1.416 isopyridoxal dehydrogenase (5-pyridoxolactone-forming) D 1.1.1.417 3beta-hydroxysteroid-4beta-carboxylate 3-dehydrogenase (decarboxylating) D 1.1.1.418 plant 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating) D 1.1.1.419 nepetalactol dehydrogenase D 1.1.1.420 D-apiose dehydrogenase D 1.1.1.421 D-apionate oxidoisomerase D 1.1.1.422 pseudoephedrine dehydrogenase D 1.1.1.423 (1R,2S)-ephedrine 1-dehydrogenase D 1.1.1.424 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,4-lactone-forming) D 1.1.1.425 levoglucosan dehydrogenase D 1.1.1.426 UDP-N-acetyl-alpha-D-quinovosamine dehydrogenase D 1.1.1.427 D-arabinose 1-dehydrogenase (NADP+) D 1.1.1.428 4-methylthio 2-oxobutanoate reductase (NADH) D 1.1.1.429 (2S)-[(R)-hydroxy(phenyl)methyl]succinyl-CoA dehydrogenase D 1.1.1.430 D-xylose reductase (NADH) D 1.1.1.431 D-xylose reductase (NADPH) D 1.1.1.432 6-dehydroglucose reductase D 1.1.1.433 sulfoacetaldehyde reductase (NADH) D 1.1.1.434 2-dehydro-3-deoxy-L-fuconate 4-dehydrogenase D 1.1.1.435 L-fucose dehydrogenase D 1.1.1.436 lactate dehydrogenase (NAD+,ferredoxin) D 1.1.1.437 5-dehydrofumagillol 5-reductase C 1.1.2 With a cytochrome as acceptor D 1.1.2.2 mannitol dehydrogenase (cytochrome) D 1.1.2.3 L-lactate dehydrogenase (cytochrome) D 1.1.2.4 D-lactate dehydrogenase (cytochrome) D 1.1.2.5 D-lactate dehydrogenase (cytochrome c-553) D 1.1.2.6 polyvinyl alcohol dehydrogenase (cytochrome) D 1.1.2.7 methanol dehydrogenase (cytochrome c) D 1.1.2.8 alcohol dehydrogenase (cytochrome c) D 1.1.2.9 1-butanol dehydrogenase (cytochrome c) D 1.1.2.10 lanthanide-dependent methanol dehydrogenase D 1.1.2.11 glucoside 3-dehydrogenase (cytochrome c) C 1.1.3 With oxygen as acceptor D 1.1.3.2 L-lactate oxidase D 1.1.3.4 glucose oxidase D 1.1.3.5 hexose oxidase D 1.1.3.6 cholesterol oxidase D 1.1.3.7 aryl-alcohol oxidase D 1.1.3.8 L-gulonolactone oxidase D 1.1.3.9 galactose oxidase D 1.1.3.10 pyranose oxidase D 1.1.3.11 L-sorbose oxidase D 1.1.3.12 pyridoxine 4-oxidase D 1.1.3.13 alcohol oxidase D 1.1.3.14 catechol oxidase (dimerizing) D 1.1.3.15 (S)-2-hydroxy-acid oxidase D 1.1.3.16 ecdysone oxidase D 1.1.3.17 choline oxidase D 1.1.3.18 secondary-alcohol oxidase D 1.1.3.19 4-hydroxymandelate oxidase (decarboxylating) D 1.1.3.20 long-chain-alcohol oxidase D 1.1.3.21 glycerol-3-phosphate oxidase D 1.1.3.23 thiamine oxidase D 1.1.3.27 hydroxyphytanate oxidase D 1.1.3.28 nucleoside oxidase D 1.1.3.29 N-acylhexosamine oxidase D 1.1.3.30 polyvinyl-alcohol oxidase D 1.1.3.37 D-arabinono-1,4-lactone oxidase D 1.1.3.38 vanillyl-alcohol oxidase D 1.1.3.39 nucleoside oxidase (H2O2-forming) D 1.1.3.40 D-mannitol oxidase D 1.1.3.41 alditol oxidase D 1.1.3.42 prosolanapyrone-II oxidase D 1.1.3.43 paromamine 6'-oxidase D 1.1.3.44 6'''-hydroxyneomycin C oxidase D 1.1.3.45 aclacinomycin-N oxidase D 1.1.3.46 4-hydroxymandelate oxidase D 1.1.3.47 5-(hydroxymethyl)furfural oxidase D 1.1.3.48 3-deoxy-alpha-D-manno-octulosonate 8-oxidase D 1.1.3.49 (R)-mandelonitrile oxidase D 1.1.3.50 C-glycoside oxidase C 1.1.5 With a quinone or similar compound as acceptor D 1.1.5.2 glucose 1-dehydrogenase (PQQ, quinone) D 1.1.5.3 glycerol-3-phosphate dehydrogenase E CH54_2342 FAD dependent oxidoreductase family protein K00111 glpA; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3] E CH54_2796 glpA; glycerol-3-phosphate dehydrogenase, anaerobic, A subunit K00111 glpA; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3] E CH54_2797 glpB; glycerol-3-phosphate dehydrogenase, anaerobic, B subunit K00112 glpB; glycerol-3-phosphate dehydrogenase subunit B [EC:1.1.5.3] D 1.1.5.4 malate dehydrogenase (quinone) D 1.1.5.5 alcohol dehydrogenase (quinone) D 1.1.5.7 cyclic alcohol dehydrogenase (quinone) D 1.1.5.8 quinate/shikimate dehydrogenase (quinone) D 1.1.5.9 glucose 1-dehydrogenase (FAD, quinone) E CH54_1387 GMC oxidoreductase family protein K19813 gdh; glucose dehydrogenase [EC:1.1.5.9] D 1.1.5.10 D-2-hydroxyacid dehydrogenase (quinone) D 1.1.5.11 1-butanol dehydrogenase (quinone) D 1.1.5.12 D-lactate dehydrogenase (quinone) E CH54_1083 FAD binding domain protein K03777 dld; D-lactate dehydrogenase (quinone) [EC:1.1.5.12] D 1.1.5.13 (S)-2-hydroxyglutarate dehydrogenase D 1.1.5.14 fructose 5-dehydrogenase E CH54_1388 membrane bound FAD containing D-sorbitol dehydrogenase family protein K23274 fdhS; fructose 5-dehydrogenase small subunit [EC:1.1.5.14] C 1.1.7 With an iron-sulfur protein as acceptor D 1.1.7.1 4-hydroxybenzoyl-CoA reductase C 1.1.9 With a copper protein as acceptor D 1.1.9.1 alcohol dehydrogenase (azurin) C 1.1.98 With other, known, physiological acceptors D 1.1.98.2 glucose-6-phosphate dehydrogenase (coenzyme-F420) D 1.1.98.3 decaprenylphospho-beta-D-ribofuranose 2-dehydrogenase D 1.1.98.4 F420H2:quinone oxidoreductase D 1.1.98.5 secondary-alcohol dehydrogenase (coenzyme-F420) D 1.1.98.6 ribonucleoside-triphosphate reductase (formate) E CH54_1943 nrdD; anaerobic ribonucleoside-triphosphate reductase K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6] D 1.1.98.7 serine-type anaerobic sulfatase-maturating enzyme C 1.1.99 With unknown physiological acceptors D 1.1.99.1 choline dehydrogenase D 1.1.99.2 L-2-hydroxyglutarate dehydrogenase D 1.1.99.3 gluconate 2-dehydrogenase (acceptor) D 1.1.99.4 dehydrogluconate dehydrogenase D 1.1.99.6 D-lactate dehydrogenase (acceptor) D 1.1.99.7 lactate---malate transhydrogenase D 1.1.99.9 pyridoxine 5-dehydrogenase D 1.1.99.12 sorbose dehydrogenase D 1.1.99.13 glucoside 3-dehydrogenase (acceptor) D 1.1.99.14 glycolate dehydrogenase D 1.1.99.18 cellobiose dehydrogenase (acceptor) D 1.1.99.20 alkan-1-ol dehydrogenase (acceptor) D 1.1.99.21 D-sorbitol dehydrogenase (acceptor) D 1.1.99.22 glycerol dehydrogenase (acceptor) D 1.1.99.24 hydroxyacid-oxoacid transhydrogenase D 1.1.99.26 3-hydroxycyclohexanone dehydrogenase D 1.1.99.27 (R)-pantolactone dehydrogenase (flavin) D 1.1.99.28 glucose-fructose oxidoreductase D 1.1.99.29 pyranose dehydrogenase (acceptor) D 1.1.99.30 2-oxo-acid reductase D 1.1.99.31 (S)-mandelate dehydrogenase D 1.1.99.32 L-sorbose 1-dehydrogenase D 1.1.99.35 soluble quinoprotein glucose dehydrogenase D 1.1.99.36 alcohol dehydrogenase (nicotinoprotein) D 1.1.99.37 methanol dehydrogenase (nicotinoprotein) D 1.1.99.38 2-deoxy-scyllo-inosamine dehydrogenase (AdoMet-dependent) D 1.1.99.39 D-2-hydroxyglutarate dehydrogenase D 1.1.99.40 (R)-2-hydroxyglutarate---pyruvate transhydrogenase D 1.1.99.41 3-hydroxy-1,2-didehydro-2,3-dihydrotabersonine reductase D 1.1.99.42 4-pyridoxic acid dehydrogenase B 1.2 Acting on the aldehyde or oxo group of donors C 1.2.1 With NAD+ or NADP+ as acceptor D 1.2.1.3 aldehyde dehydrogenase (NAD+) D 1.2.1.4 aldehyde dehydrogenase (NADP+) D 1.2.1.5 aldehyde dehydrogenase [NAD(P)+] D 1.2.1.7 benzaldehyde dehydrogenase (NADP+) D 1.2.1.8 betaine-aldehyde dehydrogenase D 1.2.1.9 glyceraldehyde-3-phosphate dehydrogenase (NADP+) D 1.2.1.10 acetaldehyde dehydrogenase (acetylating) E CH54_551 aldehyde dehydrogenase family protein K04072 adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] D 1.2.1.11 aspartate-semialdehyde dehydrogenase E CH54_2356 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] D 1.2.1.12 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) E CH54_127 gap; glyceraldehyde-3-phosphate dehydrogenase, type I K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] E CH54_577 gap; glyceraldehyde-3-phosphate dehydrogenase, type I K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] D 1.2.1.13 glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) D 1.2.1.15 malonate-semialdehyde dehydrogenase D 1.2.1.16 succinate-semialdehyde dehydrogenase [NAD(P)+] E CH54_2982 succinate-semialdehyde dehydrogenase family protein K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D 1.2.1.17 glyoxylate dehydrogenase (acylating) D 1.2.1.18 malonate-semialdehyde dehydrogenase (acetylating) E CH54_2370 mmsA; methylmalonate-semialdehyde dehydrogenase K00140 mmsA; malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27] D 1.2.1.19 aminobutyraldehyde dehydrogenase D 1.2.1.20 glutarate-semialdehyde dehydrogenase E CH54_2982 succinate-semialdehyde dehydrogenase family protein K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D 1.2.1.21 glycolaldehyde dehydrogenase D 1.2.1.22 lactaldehyde dehydrogenase D 1.2.1.23 2-oxoaldehyde dehydrogenase (NAD+) D 1.2.1.24 succinate-semialdehyde dehydrogenase (NAD+) D 1.2.1.25 branched-chain alpha-keto acid dehydrogenase system D 1.2.1.26 2,5-dioxovalerate dehydrogenase D 1.2.1.27 methylmalonate-semialdehyde dehydrogenase (CoA-acylating) E CH54_2370 mmsA; methylmalonate-semialdehyde dehydrogenase K00140 mmsA; malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27] D 1.2.1.28 benzaldehyde dehydrogenase (NAD+) D 1.2.1.29 aryl-aldehyde dehydrogenase D 1.2.1.30 carboxylate reductase (NADP+) D 1.2.1.31 L-aminoadipate-semialdehyde dehydrogenase D 1.2.1.32 aminomuconate-semialdehyde dehydrogenase D 1.2.1.33 (R)-dehydropantoate dehydrogenase D 1.2.1.36 retinal dehydrogenase D 1.2.1.38 N-acetyl-gamma-glutamyl-phosphate reductase E CH54_2697 argC; N-acetyl-gamma-glutamyl-phosphate reductase K00145 argC; N-acetyl-gamma-glutamyl-phosphate reductase [EC:1.2.1.38] D 1.2.1.39 phenylacetaldehyde dehydrogenase D 1.2.1.41 glutamate-5-semialdehyde dehydrogenase E CH54_3618 proA; glutamate-5-semialdehyde dehydrogenase K00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41] D 1.2.1.42 hexadecanal dehydrogenase (acylating) D 1.2.1.44 cinnamoyl-CoA reductase D 1.2.1.46 formaldehyde dehydrogenase D 1.2.1.47 4-trimethylammoniobutyraldehyde dehydrogenase D 1.2.1.48 long-chain-aldehyde dehydrogenase D 1.2.1.49 2-oxoaldehyde dehydrogenase (NADP+) D 1.2.1.50 long-chain acyl-protein thioester reductase D 1.2.1.51 pyruvate dehydrogenase (NADP+) D 1.2.1.52 oxoglutarate dehydrogenase (NADP+) D 1.2.1.53 4-hydroxyphenylacetaldehyde dehydrogenase D 1.2.1.54 gamma-guanidinobutyraldehyde dehydrogenase D 1.2.1.57 butanal dehydrogenase D 1.2.1.58 phenylglyoxylate dehydrogenase (acylating) D 1.2.1.59 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) D 1.2.1.60 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase D 1.2.1.61 4-hydroxymuconic-semialdehyde dehydrogenase D 1.2.1.62 4-formylbenzenesulfonate dehydrogenase D 1.2.1.63 6-oxohexanoate dehydrogenase D 1.2.1.64 4-hydroxybenzaldehyde dehydrogenase (NAD+) D 1.2.1.65 salicylaldehyde dehydrogenase D 1.2.1.67 vanillin dehydrogenase D 1.2.1.68 coniferyl-aldehyde dehydrogenase D 1.2.1.69 fluoroacetaldehyde dehydrogenase D 1.2.1.70 glutamyl-tRNA reductase E CH54_656 hemA; glutamyl-tRNA reductase K02492 hemA; glutamyl-tRNA reductase [EC:1.2.1.70] D 1.2.1.71 succinylglutamate-semialdehyde dehydrogenase E CH54_679 astD; succinylglutamate-semialdehyde dehydrogenase K06447 astD; succinylglutamic semialdehyde dehydrogenase [EC:1.2.1.71] D 1.2.1.72 erythrose-4-phosphate dehydrogenase E CH54_3390 epd; erythrose-4-phosphate dehydrogenase K03472 epd; D-erythrose 4-phosphate dehydrogenase [EC:1.2.1.72] D 1.2.1.73 sulfoacetaldehyde dehydrogenase D 1.2.1.74 abieta-7,13-dien-18-al dehydrogenase D 1.2.1.75 malonyl-CoA reductase (malonate semialdehyde-forming) D 1.2.1.76 succinate-semialdehyde dehydrogenase (acylating) D 1.2.1.77 3,4-dehydroadipyl-CoA semialdehyde dehydrogenase (NADP+) D 1.2.1.78 2-formylbenzoate dehydrogenase D 1.2.1.79 succinate-semialdehyde dehydrogenase (NADP+) E CH54_2982 succinate-semialdehyde dehydrogenase family protein K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20] D 1.2.1.80 long-chain acyl-[acyl-carrier-protein] reductase D 1.2.1.81 sulfoacetaldehyde dehydrogenase (acylating) D 1.2.1.82 beta-apo-4'-carotenal dehydrogenase D 1.2.1.83 3-succinoylsemialdehyde-pyridine dehydrogenase D 1.2.1.84 alcohol-forming fatty acyl-CoA reductase D 1.2.1.85 2-hydroxymuconate-6-semialdehyde dehydrogenase D 1.2.1.86 geranial dehydrogenase D 1.2.1.87 propanal dehydrogenase (CoA-propanoylating) E CH54_954 aldehyde dehydrogenase family protein K13922 pduP; propionaldehyde dehydrogenase [EC:1.2.1.87] D 1.2.1.88 L-glutamate gamma-semialdehyde dehydrogenase E CH54_754 delta-1-pyrroline-5-carboxylate dehydrogenase K13821 putA; RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88] D 1.2.1.89 D-glyceraldehyde dehydrogenase (NADP+) D 1.2.1.90 glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+] D 1.2.1.91 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase D 1.2.1.92 3,6-anhydro-alpha-L-galactose dehydrogenase D 1.2.1.94 farnesal dehydrogenase D 1.2.1.95 L-2-aminoadipate reductase D 1.2.1.96 4-hydroxybenzaldehyde dehydrogenase (NADP+) D 1.2.1.97 3-sulfolactaldehyde dehydrogenase D 1.2.1.98 2-hydroxy-2-methylpropanal dehydrogenase D 1.2.1.99 4-(gamma-glutamylamino)butanal dehydrogenase D 1.2.1.100 5-formyl-3-hydroxy-2-methylpyridine 4-carboxylic acid 5-dehydrogenase D 1.2.1.101 L-tyrosine reductase D 1.2.1.102 isopyridoxal dehydrogenase (5-pyridoxate-forming) D 1.2.1.103 [amino-group carrier protein]-6-phospho-L-2-aminoadipate reductase D 1.2.1.104 pyruvate dehydrogenase system D 1.2.1.105 2-oxoglutarate dehydrogenase system D 1.2.1.106 [amino-group carrier protein]-5-phospho-L-glutamate reductase D 1.2.1.107 glyceraldehyde-3-phosphate dehydrogenase (arsenate-transferring) C 1.2.2 With a cytochrome as acceptor D 1.2.2.1 formate dehydrogenase (cytochrome) C 1.2.3 With oxygen as acceptor D 1.2.3.1 aldehyde oxidase D 1.2.3.3 pyruvate oxidase D 1.2.3.4 oxalate oxidase D 1.2.3.5 glyoxylate oxidase D 1.2.3.6 pyruvate oxidase (CoA-acetylating) D 1.2.3.7 indole-3-acetaldehyde oxidase D 1.2.3.8 pyridoxal oxidase D 1.2.3.9 aryl-aldehyde oxidase D 1.2.3.13 4-hydroxyphenylpyruvate oxidase D 1.2.3.14 abscisic-aldehyde oxidase D 1.2.3.15 (methyl)glyoxal oxidase C 1.2.4 With a disulfide as acceptor D 1.2.4.1 pyruvate dehydrogenase (acetyl-transferring) E CH54_1756 aceE; pyruvate dehydrogenase (acetyl-transferring), homodimeric type K00163 aceE; pyruvate dehydrogenase E1 component [EC:1.2.4.1] D 1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring) E CH54_1147 sucA; oxoglutarate dehydrogenase (succinyl-transferring), E1 component K00164 OGDH; 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2] D 1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) C 1.2.5 With a quinone or similar compound as acceptor D 1.2.5.1 pyruvate dehydrogenase (quinone) E CH54_4062 thiamine pyrophosphate enzyme, central domain protein K00156 poxB; pyruvate dehydrogenase (quinone) [EC:1.2.5.1] D 1.2.5.2 aldehyde dehydrogenase (quinone) D 1.2.5.3 aerobic carbon monoxide dehydrogenase C 1.2.7 With an iron-sulfur protein as acceptor D 1.2.7.1 pyruvate synthase E CH54_356 nifJ; ferredoxin (flavodoxin) oxidoreductase K03737 por; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] D 1.2.7.3 2-oxoglutarate synthase D 1.2.7.4 anaerobic carbon monoxide dehydrogenase D 1.2.7.5 aldehyde ferredoxin oxidoreductase D 1.2.7.6 glyceraldehyde-3-phosphate dehydrogenase (ferredoxin) D 1.2.7.7 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) D 1.2.7.8 indolepyruvate ferredoxin oxidoreductase D 1.2.7.10 oxalate oxidoreductase D 1.2.7.11 2-oxoacid oxidoreductase (ferredoxin) D 1.2.7.12 formylmethanofuran dehydrogenase C 1.2.98 With other, known, physiological acceptors D 1.2.98.1 formaldehyde dismutase C 1.2.99 With unknown physiological acceptors D 1.2.99.6 carboxylate reductase D 1.2.99.7 aldehyde dehydrogenase (FAD-independent) D 1.2.99.8 glyceraldehyde dehydrogenase (FAD-containing) D 1.2.99.10 4,4'-diapolycopenoate synthase B 1.3 Acting on the CH-CH group of donors C 1.3.1 With NAD+ or NADP+ as acceptor D 1.3.1.1 dihydropyrimidine dehydrogenase (NAD+) D 1.3.1.2 dihydropyrimidine dehydrogenase (NADP+) D 1.3.1.3 Delta4-3-oxosteroid 5beta-reductase D 1.3.1.5 cucurbitacin Delta23-reductase D 1.3.1.6 fumarate reductase (NADH) D 1.3.1.7 meso-tartrate dehydrogenase D 1.3.1.8 acyl-CoA dehydrogenase (NADP+) D 1.3.1.9 enoyl-[acyl-carrier-protein] reductase (NADH) E CH54_2502 NAD(P)H binding domain of trans-2-enoyl-CoA reductase family protein K00209 fabV; enoyl-[acyl-carrier protein] reductase / trans-2-enoyl-CoA reductase (NAD+) [EC:1.3.1.9 1.3.1.44] D 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific) D 1.3.1.11 2-coumarate reductase D 1.3.1.12 prephenate dehydrogenase E CH54_1606 tyrA; chorismate mutase K14187 tyrA; chorismate mutase / prephenate dehydrogenase [EC:5.4.99.5 1.3.1.12] D 1.3.1.13 prephenate dehydrogenase (NADP+) D 1.3.1.14 dihydroorotate dehydrogenase (NAD+) D 1.3.1.15 dihydroorotate dehydrogenase (NADP+) D 1.3.1.16 beta-nitroacrylate reductase D 1.3.1.17 3-methyleneoxindole reductase D 1.3.1.18 kynurenate-7,8-dihydrodiol dehydrogenase D 1.3.1.19 cis-1,2-dihydrobenzene-1,2-diol dehydrogenase D 1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase D 1.3.1.21 7-dehydrocholesterol reductase D 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) D 1.3.1.24 biliverdin reductase D 1.3.1.25 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase D 1.3.1.27 2-hexadecenal reductase D 1.3.1.28 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase E CH54_3174 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase K00216 entA; 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase [EC:1.3.1.28] D 1.3.1.29 cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase D 1.3.1.31 2-enoate reductase D 1.3.1.32 maleylacetate reductase D 1.3.1.33 protochlorophyllide reductase D 1.3.1.34 2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing] E CH54_3088 flavin oxidoreductase / NADH oxidase family protein K00219 fadH; 2,4-dienoyl-CoA reductase (NADPH2) [EC:1.3.1.34] D 1.3.1.36 geissoschizine dehydrogenase D 1.3.1.37 cis-2-enoyl-CoA reductase (NADPH) D 1.3.1.38 trans-2-enoyl-CoA reductase (NADPH) D 1.3.1.39 enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific) D 1.3.1.40 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate reductase D 1.3.1.41 xanthommatin reductase D 1.3.1.42 12-oxophytodienoate reductase D 1.3.1.43 arogenate dehydrogenase D 1.3.1.44 trans-2-enoyl-CoA reductase (NAD+) E CH54_2502 NAD(P)H binding domain of trans-2-enoyl-CoA reductase family protein K00209 fabV; enoyl-[acyl-carrier protein] reductase / trans-2-enoyl-CoA reductase (NAD+) [EC:1.3.1.9 1.3.1.44] D 1.3.1.45 2'-hydroxyisoflavone reductase D 1.3.1.46 biochanin-A reductase D 1.3.1.47 alpha-santonin 1,2-reductase D 1.3.1.48 13,14-dehydro-15-oxoprostaglandin 13-reductase D 1.3.1.49 cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase D 1.3.1.51 2'-hydroxydaidzein reductase D 1.3.1.53 (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate dehydrogenase D 1.3.1.54 precorrin-6A reductase E CH54_928 cobK; precorrin-6x reductase K05895 cobK-cbiJ; precorrin-6A/cobalt-precorrin-6A reductase [EC:1.3.1.54 1.3.1.106] D 1.3.1.56 cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase D 1.3.1.57 phloroglucinol reductase D 1.3.1.58 2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase D 1.3.1.60 dibenzothiophene dihydrodiol dehydrogenase D 1.3.1.62 pimeloyl-CoA dehydrogenase D 1.3.1.64 phthalate 4,5-cis-dihydrodiol dehydrogenase D 1.3.1.65 5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline dehydrogenase D 1.3.1.66 cis-dihydroethylcatechol dehydrogenase D 1.3.1.67 cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate dehydrogenase D 1.3.1.68 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate dehydrogenase D 1.3.1.69 zeatin reductase D 1.3.1.70 Delta14-sterol reductase D 1.3.1.71 Delta24(241)-sterol reductase D 1.3.1.72 Delta24-sterol reductase D 1.3.1.73 1,2-dihydrovomilenine reductase D 1.3.1.74 2-alkenal reductase [NAD(P)+] D 1.3.1.75 3,8-divinyl protochlorophyllide a 8-vinyl-reductase (NADPH) D 1.3.1.76 precorrin-2 dehydrogenase E CH54_1695 cobA; uroporphyrinogen-III C-methyltransferase K02302 cysG; uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4] E CH54_2299 cobA; uroporphyrinogen-III C-methyltransferase K02302 cysG; uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4] D 1.3.1.77 anthocyanidin reductase [(2R,3R)-flavan-3-ol-forming] D 1.3.1.78 arogenate dehydrogenase (NADP+) D 1.3.1.79 arogenate dehydrogenase [NAD(P)+] D 1.3.1.81 (+)-pulegone reductase D 1.3.1.82 (-)-isopiperitenone reductase D 1.3.1.83 geranylgeranyl diphosphate reductase D 1.3.1.84 acrylyl-CoA reductase (NADPH) D 1.3.1.85 crotonyl-CoA carboxylase/reductase D 1.3.1.86 crotonyl-CoA reductase D 1.3.1.87 3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate dehydrogenase D 1.3.1.88 tRNA-dihydrouridine16/17 synthase [NAD(P)+] D 1.3.1.89 tRNA-dihydrouridine47 synthase [NAD(P)+] D 1.3.1.90 tRNA-dihydrouridine20a/20b synthase [NAD(P)+] D 1.3.1.91 tRNA-dihydrouridine20 synthase [NAD(P)+] D 1.3.1.92 artemisinic aldehyde Delta11(13)-reductase D 1.3.1.93 very-long-chain enoyl-CoA reductase D 1.3.1.94 polyprenol reductase D 1.3.1.95 acrylyl-CoA reductase (NADH) D 1.3.1.96 Botryococcus squalene synthase D 1.3.1.97 botryococcene synthase D 1.3.1.98 UDP-N-acetylmuramate dehydrogenase E CH54_2862 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] D 1.3.1.100 chanoclavine-I aldehyde reductase D 1.3.1.101 2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate reductase [NAD(P)H] D 1.3.1.102 2-alkenal reductase (NADP+) D 1.3.1.103 2-haloacrylate reductase D 1.3.1.104 enoyl-[acyl-carrier-protein] reductase (NADPH) D 1.3.1.105 2-methylene-furan-3-one reductase D 1.3.1.106 cobalt-precorrin-6A reductase E CH54_928 cobK; precorrin-6x reductase K05895 cobK-cbiJ; precorrin-6A/cobalt-precorrin-6A reductase [EC:1.3.1.54 1.3.1.106] D 1.3.1.107 sanguinarine reductase D 1.3.1.108 caffeoyl-CoA reductase D 1.3.1.109 butanoyl-CoA dehydrogenase complex (NAD+, ferredoxin) D 1.3.1.111 geranylgeranyl-bacteriochlorophyllide a reductase D 1.3.1.112 anthocyanidin reductase [(2S)-flavan-3-ol-forming] D 1.3.1.113 (4-alkanoyl-5-oxo-2,5-dihydrofuran-3-yl)methyl phosphate reductase D 1.3.1.114 3-dehydro-bile acid Delta4,6-reductase D 1.3.1.115 3-oxocholoyl-CoA 4-desaturase D 1.3.1.116 7beta-hydroxy-3-oxochol-24-oyl-CoA 4-desaturase D 1.3.1.117 hydroxycinnamoyl-CoA reductase D 1.3.1.118 meromycolic acid enoyl-[acyl-carrier-protein] reductase D 1.3.1.119 chlorobenzene dihydrodiol dehydrogenase D 1.3.1.120 cyclohexane-1-carbonyl-CoA reductase (NADP+) D 1.3.1.121 4-amino-4-deoxyprephenate dehydrogenase D 1.3.1.122 (S)-8-oxocitronellyl enol synthase D 1.3.1.123 8-oxogeranial reductase D 1.3.1.124 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] D 1.3.1.125 acrylate reductase D 1.3.1.126 2-epi-5-epi-valiolone dehydrogenase C 1.3.2 With a cytochrome as acceptor D 1.3.2.3 L-galactonolactone dehydrogenase D 1.3.2.4 fumarate reductase (cytochrome) C 1.3.3 With oxygen as acceptor D 1.3.3.3 coproporphyrinogen oxidase E CH54_1315 coproporphyrinogen III oxidase family protein K00228 CPOX; coproporphyrinogen III oxidase [EC:1.3.3.3] D 1.3.3.4 protoporphyrinogen oxidase D 1.3.3.5 bilirubin oxidase D 1.3.3.6 acyl-CoA oxidase D 1.3.3.7 dihydrouracil oxidase D 1.3.3.8 tetrahydroberberine oxidase D 1.3.3.10 tryptophan alpha,beta-oxidase D 1.3.3.11 pyrroloquinoline-quinone synthase D 1.3.3.12 L-galactonolactone oxidase D 1.3.3.13 albonoursin synthase D 1.3.3.14 aclacinomycin-A oxidase D 1.3.3.15 coproporphyrinogen III oxidase (coproporphyrin-forming) D 1.3.3.16 oxazoline dehydrogenase D 1.3.3.17 benzylmalonyl-CoA dehydrogenase C 1.3.4 With a disulfide as acceptor D 1.3.4.1 fumarate reductase (CoM/CoB) C 1.3.5 With a quinone or related compound as acceptor D 1.3.5.1 succinate dehydrogenase E CH54_1149 sdhA; succinate dehydrogenase, flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] E CH54_1148 succinate dehydrogenase and fumarate reductase iron-sulfur family protein K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] E CH54_2053 frdA; fumarate reductase, flavoprotein subunit K00244 frdA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] E CH54_2054 succinate dehydrogenase and fumarate reductase iron-sulfur family protein K00245 frdB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] D 1.3.5.2 dihydroorotate dehydrogenase (quinone) E CH54_4120 pyrD; dihydroorotate dehydrogenase K00254 DHODH; dihydroorotate dehydrogenase [EC:1.3.5.2] D 1.3.5.3 protoporphyrinogen IX dehydrogenase (quinone) E CH54_2857 flavodoxin domain protein K00230 hemG; menaquinone-dependent protoporphyrinogen oxidase [EC:1.3.5.3] D 1.3.5.5 15-cis-phytoene desaturase D 1.3.5.6 9,9'-dicis-zeta-carotene desaturase C 1.3.7 With an iron-sulfur protein as acceptor D 1.3.7.1 6-hydroxynicotinate reductase D 1.3.7.2 15,16-dihydrobiliverdin:ferredoxin oxidoreductase D 1.3.7.3 phycoerythrobilin:ferredoxin oxidoreductase D 1.3.7.4 phytochromobilin:ferredoxin oxidoreductase D 1.3.7.5 phycocyanobilin:ferredoxin oxidoreductase D 1.3.7.6 phycoerythrobilin synthase D 1.3.7.7 ferredoxin:protochlorophyllide reductase (ATP-dependent) D 1.3.7.8 benzoyl-CoA reductase D 1.3.7.11 2,3-bis-O-geranylgeranyl-sn-glycero-phospholipid reductase D 1.3.7.12 red chlorophyll catabolite reductase D 1.3.7.13 3,8-divinyl protochlorophyllide a 8-vinyl-reductase (ferredoxin) D 1.3.7.14 3,8-divinyl chlorophyllide a reductase D 1.3.7.15 chlorophyllide a reductase C 1.3.8 With a flavin as acceptor D 1.3.8.1 short-chain acyl-CoA dehydrogenase D 1.3.8.2 4,4'-diapophytoene desaturase (4,4'-diapolycopene-forming) D 1.3.8.3 (R)-benzylsuccinyl-CoA dehydrogenase D 1.3.8.4 isovaleryl-CoA dehydrogenase D 1.3.8.5 short-chain 2-methylacyl-CoA dehydrogenase D 1.3.8.6 glutaryl-CoA dehydrogenase (ETF) D 1.3.8.7 medium-chain acyl-CoA dehydrogenase D 1.3.8.8 long-chain acyl-CoA dehydrogenase D 1.3.8.9 very-long-chain acyl-CoA dehydrogenase D 1.3.8.10 cyclohex-1-ene-1-carbonyl-CoA dehydrogenase D 1.3.8.11 cyclohexane-1-carbonyl-CoA dehydrogenase (electron-transfer flavoprotein) D 1.3.8.12 (2S)-methylsuccinyl-CoA dehydrogenase D 1.3.8.13 crotonobetainyl-CoA reductase D 1.3.8.14 L-prolyl-[peptidyl-carrier protein] dehydrogenase D 1.3.8.15 3-(aryl)acrylate reductase D 1.3.8.16 2-amino-4-deoxychorismate dehydrogenase D 1.3.8.17 dehydro coenzyme F420 reductase C 1.3.98 With other, known, physiological acceptors D 1.3.98.1 dihydroorotate dehydrogenase (fumarate) D 1.3.98.3 coproporphyrinogen dehydrogenase E CH54_2563 hemN; oxygen-independent coproporphyrinogen III oxidase K02495 hemN; oxygen-independent coproporphyrinogen III oxidase [EC:1.3.98.3] D 1.3.98.4 5a,11a-dehydrotetracycline reductase D 1.3.98.5 hydrogen peroxide-dependent heme synthase D 1.3.98.6 AdoMet-dependent heme synthase D 1.3.98.7 [mycofactocin precursor peptide]-tyrosine decarboxylase C 1.3.99 With unknown physiological acceptors D 1.3.99.4 3-oxosteroid 1-dehydrogenase D 1.3.99.5 3-oxo-5alpha-steroid 4-dehydrogenase (acceptor) D 1.3.99.6 3-oxo-5beta-steroid 4-dehydrogenase D 1.3.99.8 2-furoyl-CoA dehydrogenase D 1.3.99.14 cyclohexanone dehydrogenase D 1.3.99.16 isoquinoline 1-oxidoreductase D 1.3.99.17 quinoline 2-oxidoreductase D 1.3.99.18 quinaldate 4-oxidoreductase D 1.3.99.19 quinoline-4-carboxylate 2-oxidoreductase D 1.3.99.23 all-trans-retinol 13,14-reductase D 1.3.99.25 carvone reductase D 1.3.99.26 all-trans-zeta-carotene desaturase D 1.3.99.27 1-hydroxycarotenoid 3,4-desaturase D 1.3.99.28 phytoene desaturase (neurosporene-forming) D 1.3.99.29 phytoene desaturase (zeta-carotene-forming) D 1.3.99.30 phytoene desaturase (3,4-didehydrolycopene-forming) D 1.3.99.31 phytoene desaturase (lycopene-forming) D 1.3.99.32 glutaryl-CoA dehydrogenase (acceptor) D 1.3.99.33 urocanate reductase D 1.3.99.36 cypemycin cysteine dehydrogenase (decarboxylating) D 1.3.99.37 1-hydroxy-2-isopentenylcarotenoid 3,4-desaturase D 1.3.99.38 menaquinone-9 beta-reductase D 1.3.99.39 carotenoid phi-ring synthase D 1.3.99.40 carotenoid chi-ring synthase D 1.3.99.41 3-(methylsulfanyl)propanoyl-CoA 2-dehydrogenase B 1.4 Acting on the CH-NH2 group of donors C 1.4.1 With NAD+ or NADP+ as acceptor D 1.4.1.1 alanine dehydrogenase D 1.4.1.2 glutamate dehydrogenase D 1.4.1.3 glutamate dehydrogenase [NAD(P)+] D 1.4.1.4 glutamate dehydrogenase (NADP+) E CH54_2387 glu/Leu/Phe/Val dehydrogenase, dimerization domain protein K00262 E1.4.1.4; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] D 1.4.1.5 L-amino-acid dehydrogenase D 1.4.1.7 serine 2-dehydrogenase D 1.4.1.8 valine dehydrogenase (NADP+) D 1.4.1.9 leucine dehydrogenase D 1.4.1.10 glycine dehydrogenase D 1.4.1.11 L-erythro-3,5-diaminohexanoate dehydrogenase D 1.4.1.12 2,4-diaminopentanoate dehydrogenase D 1.4.1.13 glutamate synthase (NADPH) E CH54_3035 glutamine amidotransferases class-II family protein K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13] E CH54_3034 glutamate synthase, small subunit domain protein K00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13] D 1.4.1.14 glutamate synthase (NADH) D 1.4.1.15 lysine dehydrogenase D 1.4.1.16 diaminopimelate dehydrogenase D 1.4.1.17 N-methylalanine dehydrogenase D 1.4.1.18 lysine 6-dehydrogenase D 1.4.1.19 tryptophan dehydrogenase D 1.4.1.20 phenylalanine dehydrogenase D 1.4.1.21 aspartate dehydrogenase D 1.4.1.23 valine dehydrogenase (NAD+) D 1.4.1.24 3-dehydroquinate synthase II D 1.4.1.25 L-arginine dehydrogenase D 1.4.1.26 2,4-diaminopentanoate dehydrogenase (NAD+) D 1.4.1.27 glycine cleavage system D 1.4.1.28 secondary-alkyl amine dehydrogenase [NAD(P)+] C 1.4.2 With a cytochrome as acceptor D 1.4.2.1 glycine dehydrogenase (cytochrome) D 1.4.2.2 nicotine dehydrogenase D 1.4.2.3 pseudooxynicotine dehydrogenase C 1.4.3 With oxygen as acceptor D 1.4.3.1 D-aspartate oxidase D 1.4.3.2 L-amino-acid oxidase D 1.4.3.3 D-amino-acid oxidase D 1.4.3.4 monoamine oxidase D 1.4.3.5 pyridoxal 5'-phosphate synthase E CH54_321 pdxH; pyridoxamine 5'-phosphate oxidase K00275 pdxH; pyridoxamine 5'-phosphate oxidase [EC:1.4.3.5] D 1.4.3.7 D-glutamate oxidase D 1.4.3.8 ethanolamine oxidase D 1.4.3.10 putrescine oxidase D 1.4.3.11 L-glutamate oxidase D 1.4.3.12 cyclohexylamine oxidase D 1.4.3.13 protein-lysine 6-oxidase D 1.4.3.14 L-lysine oxidase D 1.4.3.15 D-glutamate(D-aspartate) oxidase D 1.4.3.16 L-aspartate oxidase E CH54_1507 nadB; L-aspartate oxidase K00278 nadB; L-aspartate oxidase [EC:1.4.3.16] D 1.4.3.19 glycine oxidase D 1.4.3.20 L-lysine 6-oxidase D 1.4.3.21 primary-amine oxidase D 1.4.3.22 diamine oxidase D 1.4.3.23 7-chloro-L-tryptophan oxidase D 1.4.3.25 L-arginine oxidase D 1.4.3.26 pre-mycofactocin synthase D 1.4.3.27 homospermidine oxidase C 1.4.4 With a disulfide as acceptor D 1.4.4.2 glycine dehydrogenase (aminomethyl-transferring) E CH54_3408 gcvP; glycine dehydrogenase K00281 GLDC; glycine cleavage system P protein (glycine dehydrogenase) [EC:1.4.4.2] C 1.4.5 With a quinone or other compound as acceptor D 1.4.5.1 D-amino acid dehydrogenase (quinone) E CH54_588 ketopantoate reductase PanE/ApbA family protein K00285 dadA; D-amino-acid dehydrogenase [EC:1.4.5.1] C 1.4.7 With an iron-sulfur protein as acceptor D 1.4.7.1 glutamate synthase (ferredoxin) C 1.4.9 With a copper protein as acceptor D 1.4.9.1 methylamine dehydrogenase (amicyanin) D 1.4.9.2 aralkylamine dehydrogenase (azurin) C 1.4.99 With unknown physiological acceptors D 1.4.99.2 taurine dehydrogenase D 1.4.99.5 glycine dehydrogenase (cyanide-forming) D 1.4.99.6 D-arginine dehydrogenase B 1.5 Acting on the CH-NH group of donors C 1.5.1 With NAD+ or NADP+ as acceptor D 1.5.1.1 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase [NAD(P)H] D 1.5.1.2 pyrroline-5-carboxylate reductase E CH54_3370 proC; pyrroline-5-carboxylate reductase K00286 proC; pyrroline-5-carboxylate reductase [EC:1.5.1.2] D 1.5.1.3 dihydrofolate reductase E CH54_1822 dihydrofolate reductase family protein K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3] D 1.5.1.5 methylenetetrahydrofolate dehydrogenase (NADP+) E CH54_3763 tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain protein K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9] D 1.5.1.6 formyltetrahydrofolate dehydrogenase D 1.5.1.7 saccharopine dehydrogenase (NAD+, L-lysine-forming) D 1.5.1.8 saccharopine dehydrogenase (NADP+, L-lysine-forming) D 1.5.1.9 saccharopine dehydrogenase (NAD+, L-glutamate-forming) D 1.5.1.10 saccharopine dehydrogenase (NADP+, L-glutamate-forming) D 1.5.1.11 D-octopine dehydrogenase D 1.5.1.15 methylenetetrahydrofolate dehydrogenase (NAD+) D 1.5.1.16 D-lysopine dehydrogenase D 1.5.1.17 alanopine dehydrogenase D 1.5.1.18 ephedrine dehydrogenase D 1.5.1.19 D-nopaline dehydrogenase D 1.5.1.20 methylenetetrahydrofolate reductase [NAD(P)H] D 1.5.1.21 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NADPH) D 1.5.1.22 strombine dehydrogenase D 1.5.1.23 tauropine dehydrogenase D 1.5.1.24 N5-(carboxyethyl)ornithine synthase D 1.5.1.25 thiomorpholine-carboxylate dehydrogenase D 1.5.1.26 beta-alanopine dehydrogenase D 1.5.1.27 1,2-dehydroreticulinium reductase (NADPH) D 1.5.1.28 opine dehydrogenase D 1.5.1.30 flavin reductase (NADPH) D 1.5.1.31 berberine reductase D 1.5.1.32 vomilenine reductase D 1.5.1.33 pteridine reductase D 1.5.1.34 6,7-dihydropteridine reductase D 1.5.1.36 flavin reductase (NADH) D 1.5.1.37 FAD reductase (NADH) D 1.5.1.38 FMN reductase (NADPH) D 1.5.1.39 FMN reductase [NAD(P)H] D 1.5.1.40 8-hydroxy-5-deazaflavin:NADPH oxidoreductase D 1.5.1.41 riboflavin reductase [NAD(P)H] E CH54_2850 oxidoreductase NAD-binding domain protein K05368 fre; NAD(P)H-flavin reductase [EC:1.5.1.41] D 1.5.1.42 FMN reductase (NADH) D 1.5.1.43 carboxynorspermidine synthase D 1.5.1.44 festuclavine dehydrogenase D 1.5.1.45 FAD reductase [NAD(P)H] D 1.5.1.46 agroclavine dehydrogenase D 1.5.1.47 dihydromethanopterin reductase [NAD(P)+] D 1.5.1.48 2-methyl-1-pyrroline reductase D 1.5.1.49 1-pyrroline-2-carboxylate reductase [NAD(P)H] D 1.5.1.50 dihydromonapterin reductase D 1.5.1.51 N-[(2S)-2-amino-2-carboxyethyl]-L-glutamate dehydrogenase D 1.5.1.52 staphylopine dehydrogenase D 1.5.1.53 methylenetetrahydrofolate reductase (NADPH) D 1.5.1.54 methylenetetrahydrofolate reductase (NADH) E CH54_2694 metF; methylenetetrahydrofolate reductase [NAD(P)H] K00297 metF; methylenetetrahydrofolate reductase (NADH) [EC:1.5.1.54] C 1.5.3 With oxygen as acceptor D 1.5.3.1 sarcosine oxidase (formaldehyde-forming) D 1.5.3.2 N-methyl-L-amino-acid oxidase D 1.5.3.4 N6-methyl-lysine oxidase D 1.5.3.5 (S)-6-hydroxynicotine oxidase D 1.5.3.6 (R)-6-hydroxynicotine oxidase D 1.5.3.7 L-pipecolate oxidase D 1.5.3.10 dimethylglycine oxidase D 1.5.3.12 dihydrobenzophenanthridine oxidase D 1.5.3.13 N1-acetylpolyamine oxidase D 1.5.3.14 polyamine oxidase (propane-1,3-diamine-forming) D 1.5.3.15 N8-acetylspermidine oxidase (propane-1,3-diamine-forming) D 1.5.3.16 spermine oxidase D 1.5.3.17 non-specific polyamine oxidase D 1.5.3.18 L-saccharopine oxidase D 1.5.3.19 4-methylaminobutanoate oxidase (formaldehyde-forming) D 1.5.3.20 N-alkylglycine oxidase D 1.5.3.21 4-methylaminobutanoate oxidase (methylamine-forming) D 1.5.3.22 coenzyme F420H2 oxidase D 1.5.3.23 glyphosate oxidoreductase D 1.5.3.24 sarcosine oxidase (5,10-methylenetetrahydrofolate-forming) D 1.5.3.25 fructosyl amine oxidase (glucosone-forming) D 1.5.3.26 fructosyl amine oxidase (fructosamine-forming) C 1.5.4 With a disulfide as acceptor D 1.5.4.1 pyrimidodiazepine synthase C 1.5.5 With a quinone or similar compound as acceptor D 1.5.5.1 electron-transferring-flavoprotein dehydrogenase D 1.5.5.2 proline dehydrogenase E CH54_754 delta-1-pyrroline-5-carboxylate dehydrogenase K13821 putA; RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88] D 1.5.5.3 hydroxyproline dehydrogenase C 1.5.7 With an iron-sulfur protein as acceptor D 1.5.7.1 methylenetetrahydrofolate reductase (ferredoxin) D 1.5.7.2 coenzyme F420 oxidoreductase (ferredoxin) D 1.5.7.3 N,N-dimethylglycine/sarcosine dehydrogenase (ferredoxin) C 1.5.8 With a flavin or flavoprotein as acceptor D 1.5.8.1 dimethylamine dehydrogenase D 1.5.8.2 trimethylamine dehydrogenase D 1.5.8.3 sarcosine dehydrogenase D 1.5.8.4 dimethylglycine dehydrogenase C 1.5.98 With other, known, physiological acceptors D 1.5.98.1 methylenetetrahydromethanopterin dehydrogenase D 1.5.98.2 5,10-methylenetetrahydromethanopterin reductase D 1.5.98.3 coenzyme F420:methanophenazine dehydrogenase C 1.5.99 With unknown physiological acceptors D 1.5.99.3 L-pipecolate dehydrogenase D 1.5.99.4 nicotine 6-hydroxylase D 1.5.99.5 methylglutamate dehydrogenase D 1.5.99.6 spermidine dehydrogenase D 1.5.99.12 cytokinin dehydrogenase D 1.5.99.13 D-proline dehydrogenase D 1.5.99.14 6-hydroxypseudooxynicotine dehydrogenase D 1.5.99.15 dihydromethanopterin reductase (acceptor) B 1.6 Acting on NADH or NADPH C 1.6.1 With NAD+ or NADP+ as acceptor D 1.6.1.1 NAD(P)+ transhydrogenase (Si-specific) E CH54_2710 pyridine nucleotide-disulfide oxidoreductase family protein K00322 sthA; NAD(P) transhydrogenase [EC:1.6.1.1] D 1.6.1.3 NAD(P)+ transhydrogenase D 1.6.1.4 NAD(P)+ transhydrogenase (ferredoxin) C 1.6.2 With a heme protein as acceptor D 1.6.2.2 cytochrome-b5 reductase D 1.6.2.4 NADPH---hemoprotein reductase D 1.6.2.5 NADPH---cytochrome-c2 reductase D 1.6.2.6 leghemoglobin reductase C 1.6.3 With oxygen as acceptor D 1.6.3.1 NAD(P)H oxidase (H2O2-forming) D 1.6.3.2 NAD(P)H oxidase (H2O-forming) D 1.6.3.3 NADH oxidase (H2O2-forming) D 1.6.3.4 NADH oxidase (H2O-forming) D 1.6.3.5 renalase C 1.6.5 With a quinone or similar compound as acceptor D 1.6.5.2 NAD(P)H dehydrogenase (quinone) E CH54_749 wrbA; quinone oxidoreductase, type IV K03809 wrbA; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2] E CH54_130 3-beta hydroxysteroid dehydrogenase/isomerase family protein K19267 qorB; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2] D 1.6.5.4 monodehydroascorbate reductase (NADH) D 1.6.5.5 NADPH:quinone reductase E CH54_2934 zinc-binding dehydrogenase family protein K00344 qor; NADPH:quinone reductase [EC:1.6.5.5] E CH54_826 NAD(P)H quinone oxidoreductase, PIG3 family protein K00344 qor; NADPH:quinone reductase [EC:1.6.5.5] E CH54_892 zinc-binding dehydrogenase family protein K00344 qor; NADPH:quinone reductase [EC:1.6.5.5] E CH54_1859 zinc-binding alcohol dehydrogenase family protein K00344 qor; NADPH:quinone reductase [EC:1.6.5.5] D 1.6.5.6 p-benzoquinone reductase (NADPH) D 1.6.5.7 2-hydroxy-1,4-benzoquinone reductase D 1.6.5.9 NADH:quinone reductase (non-electrogenic) E CH54_100 pyridine nucleotide-disulfide oxidoreductase family protein K03885 ndh; NADH:quinone reductase (non-electrogenic) [EC:1.6.5.9] D 1.6.5.10 NADPH dehydrogenase (quinone) E CH54_3129 flavodoxin-like fold family protein K03923 mdaB; NADPH dehydrogenase (quinone) [EC:1.6.5.10] D 1.6.5.12 demethylphylloquinone reductase C 1.6.99 With unknown physiological acceptors D 1.6.99.1 NADPH dehydrogenase B 1.7 Acting on other nitrogenous compounds as donors C 1.7.1 With NAD+ or NADP+ as acceptor D 1.7.1.1 nitrate reductase (NADH) D 1.7.1.2 nitrate reductase [NAD(P)H] D 1.7.1.3 nitrate reductase (NADPH) D 1.7.1.4 nitrite reductase [NAD(P)H] D 1.7.1.5 hyponitrite reductase D 1.7.1.6 azobenzene reductase D 1.7.1.7 GMP reductase E CH54_1765 guaC; guanosine monophosphate reductase K00364 guaC; GMP reductase [EC:1.7.1.7] D 1.7.1.9 nitroquinoline-N-oxide reductase D 1.7.1.10 hydroxylamine reductase (NADH) D 1.7.1.11 4-(dimethylamino)phenylazoxybenzene reductase D 1.7.1.12 N-hydroxy-2-acetamidofluorene reductase D 1.7.1.13 preQ1 synthase E CH54_3511 queF; queuine synthase K06879 queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13] D 1.7.1.14 nitric oxide reductase [NAD(P)+, nitrous oxide-forming] D 1.7.1.15 nitrite reductase (NADH) E CH54_2296 nirB; nitrite reductase [NAD(P)H], large subunit K00362 nirB; nitrite reductase (NADH) large subunit [EC:1.7.1.15] E CH54_2297 nirD; nitrite reductase [NAD(P)H], small subunit K00363 nirD; nitrite reductase (NADH) small subunit [EC:1.7.1.15] D 1.7.1.16 nitrobenzene nitroreductase D 1.7.1.17 FMN-dependent NADH-azoreductase E CH54_364 NADPH-dependent FMN reductase family protein K01118 acpD; FMN-dependent NADH-azoreductase [EC:1.7.1.17] C 1.7.2 With a cytochrome as acceptor D 1.7.2.1 nitrite reductase (NO-forming) D 1.7.2.2 nitrite reductase (cytochrome; ammonia-forming) E CH54_37 cytochrome c552 family protein K03385 nrfA; nitrite reductase (cytochrome c-552) [EC:1.7.2.2] D 1.7.2.3 trimethylamine-N-oxide reductase D 1.7.2.4 nitrous-oxide reductase D 1.7.2.5 nitric oxide reductase (cytochrome c) D 1.7.2.6 hydroxylamine dehydrogenase D 1.7.2.7 hydrazine synthase D 1.7.2.8 hydrazine dehydrogenase D 1.7.2.9 hydroxylamine oxidase C 1.7.3 With oxygen as acceptor D 1.7.3.1 nitroalkane oxidase D 1.7.3.2 acetylindoxyl oxidase D 1.7.3.3 factor-independent urate hydroxylase D 1.7.3.5 3-aci-nitropropanoate oxidase D 1.7.3.6 hydroxylamine oxidase (cytochrome) C 1.7.5 With a quinone or similar compound as acceptor D 1.7.5.1 nitrate reductase (quinone) D 1.7.5.2 nitric oxide reductase (menaquinol) C 1.7.6 With a nitrogenous group as acceptor D 1.7.6.1 nitrite dismutase C 1.7.7 With an iron-sulfur protein as acceptor D 1.7.7.1 ferredoxin---nitrite reductase D 1.7.7.2 ferredoxin---nitrate reductase C 1.7.99 With unknown physiological acceptors D 1.7.99.1 hydroxylamine reductase E CH54_4064 hcp; hydroxylamine reductase K05601 hcp; hydroxylamine reductase [EC:1.7.99.1] B 1.8 Acting on a sulfur group of donors C 1.8.1 With NAD+ or NADP+ as acceptor D 1.8.1.2 assimilatory sulfite reductase (NADPH) E CH54_1699 sulfite reductase [NADPH] flavoprotein, alpha-component K00380 cysJ; sulfite reductase (NADPH) flavoprotein alpha-component [EC:1.8.1.2] E CH54_1698 cysI; sulfite reductase (NADPH) hemoprotein, beta-component K00381 cysI; sulfite reductase (NADPH) hemoprotein beta-component [EC:1.8.1.2] D 1.8.1.4 dihydrolipoyl dehydrogenase E CH54_2708 pyridine nucleotide-disulfide oxidoreductase family protein K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] E CH54_1754 lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] D 1.8.1.5 2-oxopropyl-CoM reductase (carboxylating) D 1.8.1.6 cystine reductase D 1.8.1.7 glutathione-disulfide reductase E CH54_2392 gor; glutathione-disulfide reductase K00383 GSR; glutathione reductase (NADPH) [EC:1.8.1.7] D 1.8.1.8 protein-disulfide reductase E CH54_3564 trxA; thioredoxin K03672 trxC; thioredoxin 2 [EC:1.8.1.8] D 1.8.1.9 thioredoxin-disulfide reductase E CH54_4078 trxB; thioredoxin-disulfide reductase K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9] D 1.8.1.10 CoA-glutathione reductase D 1.8.1.11 asparagusate reductase D 1.8.1.12 trypanothione-disulfide reductase D 1.8.1.13 bis-gamma-glutamylcystine reductase D 1.8.1.14 CoA-disulfide reductase D 1.8.1.15 mycothione reductase D 1.8.1.16 glutathione amide reductase D 1.8.1.17 dimethylsulfone reductase D 1.8.1.18 NAD(P)H sulfur oxidoreductase (CoA-dependent) D 1.8.1.19 sulfide dehydrogenase D 1.8.1.20 4,4'-dithiodibutanoate disulfide reductase D 1.8.1.21 dissimilatory dimethyldisulfide reductase D 1.8.1.22 dissimilatory sulfite reductase system C 1.8.2 With a cytochrome as acceptor D 1.8.2.1 sulfite dehydrogenase (cytochrome) D 1.8.2.2 thiosulfate dehydrogenase D 1.8.2.3 sulfide-cytochrome-c reductase (flavocytochrome c) D 1.8.2.4 dimethyl sulfide:cytochrome c2 reductase D 1.8.2.5 thiosulfate reductase (cytochrome) D 1.8.2.6 S-disulfanyl-L-cysteine oxidoreductase D 1.8.2.7 thiocyanate desulfurase C 1.8.3 With oxygen as acceptor D 1.8.3.1 sulfite oxidase D 1.8.3.2 thiol oxidase D 1.8.3.3 glutathione oxidase D 1.8.3.4 methanethiol oxidase D 1.8.3.5 prenylcysteine oxidase D 1.8.3.6 farnesylcysteine lyase D 1.8.3.7 formylglycine-generating enzyme C 1.8.4 With a disulfide as acceptor D 1.8.4.1 glutathione---homocystine transhydrogenase D 1.8.4.2 protein-disulfide reductase (glutathione) D 1.8.4.3 glutathione---CoA-glutathione transhydrogenase D 1.8.4.4 glutathione---cystine transhydrogenase D 1.8.4.7 enzyme-thiol transhydrogenase (glutathione-disulfide) D 1.8.4.8 phosphoadenylyl-sulfate reductase (thioredoxin) E CH54_1697 cysH; phosphoadenosine phosphosulfate reductase K00390 cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10] D 1.8.4.9 adenylyl-sulfate reductase (glutathione) D 1.8.4.10 adenylyl-sulfate reductase (thioredoxin) E CH54_1697 cysH; phosphoadenosine phosphosulfate reductase K00390 cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10] D 1.8.4.11 peptide-methionine (S)-S-oxide reductase E CH54_2011 msrA; peptide-methionine (S)-S-oxide reductase K07304 msrA; peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11] D 1.8.4.12 peptide-methionine (R)-S-oxide reductase E CH54_576 msrB; methionine-R-sulfoxide reductase K07305 msrB; peptide-methionine (R)-S-oxide reductase [EC:1.8.4.12] D 1.8.4.13 L-methionine (S)-S-oxide reductase D 1.8.4.14 L-methionine (R)-S-oxide reductase E CH54_215 hypothetical protein K08968 msrC; L-methionine (R)-S-oxide reductase [EC:1.8.4.14] D 1.8.4.15 protein dithiol oxidoreductase (disulfide-forming) E CH54_2559 DSBA-like thioredoxin domain protein K03673 dsbA; protein dithiol oxidoreductase (disulfide-forming) [EC:1.8.4.15] E CH54_1667 DSBA-like thioredoxin domain protein K03673 dsbA; protein dithiol oxidoreductase (disulfide-forming) [EC:1.8.4.15] D 1.8.4.16 thioredoxin:protein disulfide reductase E CH54_2069 cytochrome C biogenesis transmembrane region family protein K04084 dsbD; thioredoxin:protein disulfide reductase [EC:1.8.4.16] C 1.8.5 With a quinone or similar compound as acceptor D 1.8.5.1 glutathione dehydrogenase (ascorbate) D 1.8.5.2 thiosulfate dehydrogenase (quinone) D 1.8.5.3 respiratory dimethylsulfoxide reductase E CH54_1635 anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family protein K07306 dmsA; anaerobic dimethyl sulfoxide reductase subunit A [EC:1.8.5.3] E CH54_1256 anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family protein K07306 dmsA; anaerobic dimethyl sulfoxide reductase subunit A [EC:1.8.5.3] D 1.8.5.4 bacterial sulfide:quinone reductase E CH54_1704 pyridine nucleotide-disulfide oxidoreductase family protein K17218 sqr; sulfide:quinone oxidoreductase [EC:1.8.5.4] D 1.8.5.5 thiosulfate reductase (quinone) D 1.8.5.6 sulfite dehydrogenase (quinone) D 1.8.5.7 glutathionyl-hydroquinone reductase E CH54_3067 hypothetical protein K07393 ECM4; glutathionyl-hydroquinone reductase [EC:1.8.5.7] D 1.8.5.8 eukaryotic sulfide quinone oxidoreductase D 1.8.5.9 protein dithiol:quinone oxidoreductase DsbB E CH54_592 disulfide bond formation DsbB family protein K03611 dsbB; protein dithiol:quinone oxidoreductase [EC:1.8.5.9] D 1.8.5.10 [DsrC]-trisulfide reductase C 1.8.7 With an iron-sulfur protein as acceptor D 1.8.7.1 assimilatory sulfite reductase (ferredoxin) D 1.8.7.2 ferredoxin:thioredoxin reductase D 1.8.7.3 ferredoxin:CoB-CoM heterodisulfide reductase C 1.8.98 With other, known, physiological acceptors D 1.8.98.1 dihydromethanophenazine:CoB-CoM heterodisulfide reductase D 1.8.98.2 sulfiredoxin D 1.8.98.3 sulfite reductase (coenzyme F420) D 1.8.98.4 coenzyme F420:CoB-CoM heterodisulfide,ferredoxin reductase D 1.8.98.5 H2:CoB-CoM heterodisulfide,ferredoxin reductase D 1.8.98.6 formate:CoB-CoM heterodisulfide,ferredoxin reductase D 1.8.98.7 cysteine-type anaerobic sulfatase-maturating enzyme C 1.8.99 With unknown physiological acceptors D 1.8.99.2 adenylyl-sulfate reductase B 1.9 Acting on a heme group of donors C 1.9.6 With a nitrogenous group as acceptor D 1.9.6.1 nitrate reductase (cytochrome) E CH54_1323 napA; periplasmic nitrate reductase, large subunit K02567 napA; nitrate reductase (cytochrome) [EC:1.9.6.1] C 1.9.98 With other, known, physiological acceptors D 1.9.98.1 iron---cytochrome-c reductase B 1.10 Acting on diphenols and related substances as donors C 1.10.1 With NAD+ or NADP+ as acceptor D 1.10.1.1 trans-acenaphthene-1,2-diol dehydrogenase C 1.10.3 With oxygen as acceptor D 1.10.3.1 catechol oxidase D 1.10.3.2 laccase D 1.10.3.3 L-ascorbate oxidase D 1.10.3.4 o-aminophenol oxidase D 1.10.3.5 3-hydroxyanthranilate oxidase D 1.10.3.6 rifamycin-B oxidase D 1.10.3.9 photosystem II D 1.10.3.11 ubiquinol oxidase (non-electrogenic) D 1.10.3.15 grixazone synthase D 1.10.3.16 dihydrophenazinedicarboxylate synthase D 1.10.3.17 superoxide oxidase C 1.10.5 With a quinone or related compound as acceptor D 1.10.5.1 ribosyldihydronicotinamide dehydrogenase (quinone) B 1.11 Acting on a peroxide as acceptor C 1.11.1 Peroxidases D 1.11.1.1 NADH peroxidase D 1.11.1.2 NADPH peroxidase D 1.11.1.3 fatty-acid peroxidase D 1.11.1.5 cytochrome-c peroxidase E CH54_1656 cytochrome c family protein K00428 E1.11.1.5; cytochrome c peroxidase [EC:1.11.1.5] D 1.11.1.6 catalase E CH54_3956 catalase family protein K03781 katE; catalase [EC:1.11.1.6] D 1.11.1.7 peroxidase D 1.11.1.8 iodide peroxidase D 1.11.1.9 glutathione peroxidase E CH54_262 glutathione peroxidase family protein K00432 gpx; glutathione peroxidase [EC:1.11.1.9] D 1.11.1.10 chloride peroxidase D 1.11.1.11 L-ascorbate peroxidase D 1.11.1.12 phospholipid-hydroperoxide glutathione peroxidase D 1.11.1.13 manganese peroxidase D 1.11.1.14 lignin peroxidase D 1.11.1.16 versatile peroxidase D 1.11.1.17 glutathione amide-dependent peroxidase D 1.11.1.18 bromide peroxidase D 1.11.1.19 dye decolorizing peroxidase D 1.11.1.20 prostamide/prostaglandin F2alpha synthase D 1.11.1.21 catalase-peroxidase D 1.11.1.22 hydroperoxy fatty acid reductase D 1.11.1.23 (S)-2-hydroxypropylphosphonic acid epoxidase D 1.11.1.24 thioredoxin-dependent peroxiredoxin E CH54_3651 hypothetical protein K03386 PRDX2_4; peroxiredoxin 2/4 [EC:1.11.1.24] E CH54_1347 redoxin family protein K03564 BCP; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24] E CH54_348 ahpC/TSA family protein K11065 tpx; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24] D 1.11.1.25 glutaredoxin-dependent peroxiredoxin D 1.11.1.26 NADH-dependent peroxiredoxin D 1.11.1.27 glutathione-dependent peroxiredoxin E CH54_2709 hypothetical protein K24136 pgdX; glutathione-dependent peroxiredoxin [EC:1.11.1.27] D 1.11.1.28 lipoyl-dependent peroxiredoxin E CH54_2428 peroxiredoxin, Ohr subfamily protein K04063 osmC; lipoyl-dependent peroxiredoxin [EC:1.11.1.28] D 1.11.1.29 mycoredoxin-dependent peroxiredoxin C 1.11.2 Peroxygenases D 1.11.2.1 unspecific peroxygenase D 1.11.2.2 myeloperoxidase D 1.11.2.3 plant seed peroxygenase D 1.11.2.4 fatty-acid peroxygenase D 1.11.2.5 3-methyl-L-tyrosine peroxygenase D 1.11.2.6 L-tyrosine peroxygenase B 1.12 Acting on hydrogen as donor C 1.12.1 With NAD+ or NADP+ as acceptor D 1.12.1.2 hydrogen dehydrogenase D 1.12.1.3 hydrogen dehydrogenase (NADP+) D 1.12.1.4 hydrogenase (NAD+, ferredoxin) D 1.12.1.5 hydrogen dehydrogenase [NAD(P)+] C 1.12.2 With a cytochrome as acceptor D 1.12.2.1 cytochrome-c3 hydrogenase C 1.12.5 With a quinone or similar compound as acceptor D 1.12.5.1 hydrogen:quinone oxidoreductase C 1.12.7 With an iron-sulfur protein as acceptor D 1.12.7.2 ferredoxin hydrogenase C 1.12.98 With other, known, physiological acceptors D 1.12.98.1 coenzyme F420 hydrogenase D 1.12.98.2 5,10-methenyltetrahydromethanopterin hydrogenase D 1.12.98.3 Methanosarcina-phenazine hydrogenase D 1.12.98.4 sulfhydrogenase C 1.12.99 With unknown physiological acceptors D 1.12.99.6 hydrogenase (acceptor) E CH54_3222 nickel-dependent hydrogenase family protein K06281 hyaB; hydrogenase large subunit [EC:1.12.99.6] E CH54_3219 hydrogenase family protein K06282 hyaA; hydrogenase small subunit [EC:1.12.99.6] B 1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases) C 1.13.11 With incorporation of two atoms of oxygen D 1.13.11.1 catechol 1,2-dioxygenase D 1.13.11.2 catechol 2,3-dioxygenase D 1.13.11.3 protocatechuate 3,4-dioxygenase D 1.13.11.4 gentisate 1,2-dioxygenase D 1.13.11.5 homogentisate 1,2-dioxygenase D 1.13.11.6 3-hydroxyanthranilate 3,4-dioxygenase D 1.13.11.8 protocatechuate 4,5-dioxygenase D 1.13.11.9 2,5-dihydroxypyridine 5,6-dioxygenase D 1.13.11.10 7,8-dihydroxykynurenate 8,8a-dioxygenase D 1.13.11.11 tryptophan 2,3-dioxygenase D 1.13.11.12 linoleate 13S-lipoxygenase D 1.13.11.14 2,3-dihydroxybenzoate 3,4-dioxygenase D 1.13.11.15 3,4-dihydroxyphenylacetate 2,3-dioxygenase D 1.13.11.16 3-carboxyethylcatechol 2,3-dioxygenase D 1.13.11.17 indole 2,3-dioxygenase D 1.13.11.18 persulfide dioxygenase D 1.13.11.19 cysteamine dioxygenase D 1.13.11.20 cysteine dioxygenase D 1.13.11.22 caffeate 3,4-dioxygenase D 1.13.11.23 2,3-dihydroxyindole 2,3-dioxygenase D 1.13.11.24 quercetin 2,3-dioxygenase E CH54_2361 pirin family protein K06911 PIR; quercetin 2,3-dioxygenase [EC:1.13.11.24] E CH54_584 pirin family protein K06911 PIR; quercetin 2,3-dioxygenase [EC:1.13.11.24] D 1.13.11.25 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase D 1.13.11.26 peptide-tryptophan 2,3-dioxygenase D 1.13.11.27 4-hydroxyphenylpyruvate dioxygenase D 1.13.11.28 2,3-dihydroxybenzoate 2,3-dioxygenase D 1.13.11.29 stizolobate synthase D 1.13.11.30 stizolobinate synthase D 1.13.11.31 arachidonate 12-lipoxygenase D 1.13.11.33 arachidonate 15-lipoxygenase D 1.13.11.34 arachidonate 5-lipoxygenase D 1.13.11.35 pyrogallol 1,2-oxygenase D 1.13.11.36 chloridazon-catechol dioxygenase D 1.13.11.37 hydroxyquinol 1,2-dioxygenase D 1.13.11.38 1-hydroxy-2-naphthoate 1,2-dioxygenase D 1.13.11.39 biphenyl-2,3-diol 1,2-dioxygenase D 1.13.11.40 arachidonate 8-lipoxygenase D 1.13.11.41 2,4'-dihydroxyacetophenone dioxygenase D 1.13.11.43 lignostilbene alphabeta-dioxygenase D 1.13.11.45 linoleate 11-lipoxygenase D 1.13.11.46 4-hydroxymandelate synthase D 1.13.11.47 3-hydroxy-4-oxoquinoline 2,4-dioxygenase D 1.13.11.48 3-hydroxy-2-methylquinolin-4-one 2,4-dioxygenase D 1.13.11.49 chlorite O2-lyase D 1.13.11.50 acetylacetone-cleaving enzyme D 1.13.11.51 9-cis-epoxycarotenoid dioxygenase D 1.13.11.52 indoleamine 2,3-dioxygenase D 1.13.11.53 acireductone dioxygenase (Ni2+-requiring) E CH54_3576 ARD/ARD' family protein K08967 mtnD; 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase [EC:1.13.11.53 1.13.11.54] D 1.13.11.54 acireductone dioxygenase [iron(II)-requiring] E CH54_3576 ARD/ARD' family protein K08967 mtnD; 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase [EC:1.13.11.53 1.13.11.54] D 1.13.11.55 sulfur oxygenase/reductase D 1.13.11.56 1,2-dihydroxynaphthalene dioxygenase D 1.13.11.57 gallate dioxygenase D 1.13.11.58 linoleate 9S-lipoxygenase D 1.13.11.59 torulene dioxygenase D 1.13.11.60 linoleate 8R-lipoxygenase D 1.13.11.61 linolenate 9R-lipoxygenase D 1.13.11.62 linoleate 10R-lipoxygenase D 1.13.11.63 beta-carotene 15,15'-dioxygenase D 1.13.11.64 5-nitrosalicylate dioxygenase D 1.13.11.65 carotenoid isomerooxygenase D 1.13.11.66 hydroquinone 1,2-dioxygenase D 1.13.11.67 8'-apo-beta-carotenoid 14',13'-cleaving dioxygenase D 1.13.11.68 9-cis-beta-carotene 9',10'-cleaving dioxygenase D 1.13.11.69 carlactone synthase D 1.13.11.70 all-trans-10'-apo-beta-carotenal 13,14-cleaving dioxygenase D 1.13.11.71 carotenoid-9',10'-cleaving dioxygenase D 1.13.11.72 2-hydroxyethylphosphonate dioxygenase D 1.13.11.73 methylphosphonate synthase D 1.13.11.74 2-aminophenol 1,6-dioxygenase D 1.13.11.75 all-trans-8'-apo-beta-carotenal 15,15'-oxygenase D 1.13.11.76 2-amino-5-chlorophenol 1,6-dioxygenase D 1.13.11.77 oleate 10S-lipoxygenase D 1.13.11.78 2-amino-1-hydroxyethylphosphonate dioxygenase (glycine-forming) D 1.13.11.79 aerobic 5,6-dimethylbenzimidazole synthase D 1.13.11.80 (3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase D 1.13.11.81 7,8-dihydroneopterin oxygenase E CH54_3108 folB; dihydroneopterin aldolase K01633 folB; 7,8-dihydroneopterin aldolase/epimerase/oxygenase [EC:4.1.2.25 5.1.99.8 1.13.11.81] D 1.13.11.82 8'-apo-carotenoid 13,14-cleaving dioxygenase D 1.13.11.83 4-hydroxy-3-prenylphenylpyruvate oxygenase D 1.13.11.84 crocetin dialdehyde synthase D 1.13.11.85 exo-cleaving rubber dioxygenase D 1.13.11.86 5-aminosalicylate 1,2-dioxygenase D 1.13.11.87 endo-cleaving rubber dioxygenase D 1.13.11.88 isoeugenol monooxygenase D 1.13.11.89 (hydroxymethyl)phosphonate dioxygenase D 1.13.11.90 [1-hydroxy-2-(trimethylamino)ethyl]phosphonate dioxygenase (glycine-betaine-forming) D 1.13.11.91 3-mercaptopropionate dioxygenase D 1.13.11.92 fatty acid alpha-dioxygenase D 1.13.11.93 2-oxoadipate dioxygenase/decarboxylase E CH54_4101 hypothetical protein K25986 ydcJ; 2-oxoadipate dioxygenase/decarboxylase [EC:1.13.11.93] C 1.13.12 With incorporation of one atom of oxygen (internal monooxygenases or internal mixed-function oxidases) D 1.13.12.1 arginine 2-monooxygenase D 1.13.12.2 lysine 2-monooxygenase D 1.13.12.3 tryptophan 2-monooxygenase D 1.13.12.4 lactate 2-monooxygenase D 1.13.12.5 Renilla-type luciferase D 1.13.12.6 Cypridina-luciferin 2-monooxygenase D 1.13.12.7 firefly luciferase D 1.13.12.8 Watasenia-luciferin 2-monooxygenase D 1.13.12.9 phenylalanine 2-monooxygenase D 1.13.12.13 Oplophorus-luciferin 2-monooxygenase D 1.13.12.15 3,4-dihydroxyphenylalanine oxidative deaminase D 1.13.12.16 nitronate monooxygenase D 1.13.12.17 dichloroarcyriaflavin A synthase D 1.13.12.18 dinoflagellate luciferase D 1.13.12.19 2-oxoglutarate dioxygenase (ethene-forming) D 1.13.12.20 noranthrone monooxygenase D 1.13.12.21 tetracenomycin-F1 monooxygenase D 1.13.12.22 deoxynogalonate monooxygenase D 1.13.12.23 4-hydroxy-3-prenylbenzoate synthase D 1.13.12.24 calcium-regulated photoprotein C 1.13.99 Miscellaneous D 1.13.99.1 inositol oxygenase D 1.13.99.3 tryptophan 2'-dioxygenase B 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen C 1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor D 1.14.11.1 gamma-butyrobetaine dioxygenase D 1.14.11.2 procollagen-proline 4-dioxygenase D 1.14.11.3 pyrimidine-deoxynucleoside 2'-dioxygenase D 1.14.11.4 procollagen-lysine 5-dioxygenase D 1.14.11.6 thymine dioxygenase D 1.14.11.7 procollagen-proline 3-dioxygenase D 1.14.11.8 trimethyllysine dioxygenase D 1.14.11.9 flavanone 3-dioxygenase D 1.14.11.10 pyrimidine-deoxynucleoside 1'-dioxygenase D 1.14.11.11 hyoscyamine (6S)-dioxygenase D 1.14.11.12 gibberellin-44 dioxygenase D 1.14.11.13 gibberellin 2beta-dioxygenase D 1.14.11.15 gibberellin 3beta-dioxygenase D 1.14.11.16 peptide-aspartate beta-dioxygenase D 1.14.11.17 taurine dioxygenase E CH54_2273 taurine catabolism dioxygenase TauD, TfdA family protein K03119 tauD; taurine dioxygenase [EC:1.14.11.17] D 1.14.11.18 phytanoyl-CoA dioxygenase D 1.14.11.20 deacetoxyvindoline 4-hydroxylase D 1.14.11.21 clavaminate synthase D 1.14.11.24 2'-deoxymugineic-acid 2'-dioxygenase D 1.14.11.25 mugineic-acid 3-dioxygenase D 1.14.11.26 deacetoxycephalosporin-C hydroxylase D 1.14.11.27 [histone H3]-dimethyl-L-lysine36 demethylase D 1.14.11.28 proline 3-hydroxylase D 1.14.11.29 hypoxia-inducible factor-proline dioxygenase D 1.14.11.30 hypoxia-inducible factor-asparagine dioxygenase D 1.14.11.31 thebaine 6-O-demethylase D 1.14.11.32 codeine 3-O-demethylase D 1.14.11.33 DNA oxidative demethylase E CH54_3155 2OG-Fe(II) oxygenase superfamily protein K03919 alkB; DNA oxidative demethylase [EC:1.14.11.33] D 1.14.11.35 1-deoxypentalenic acid 11beta-hydroxylase D 1.14.11.36 pentalenolactone F synthase D 1.14.11.37 kanamycin B dioxygenase D 1.14.11.38 verruculogen synthase D 1.14.11.39 L-asparagine hydroxylase D 1.14.11.40 enduracididine beta-hydroxylase D 1.14.11.41 L-arginine hydroxylase D 1.14.11.42 tRNAPhe (7-(3-amino-3-carboxypropyl)wyosine37-C2)-hydroxylase D 1.14.11.43 (S)-dichlorprop dioxygenase (2-oxoglutarate) D 1.14.11.44 (R)-dichlorprop dioxygenase (2-oxoglutarate) D 1.14.11.45 L-isoleucine 4-hydroxylase D 1.14.11.46 2-aminoethylphosphonate dioxygenase D 1.14.11.47 [50S ribosomal protein L16]-arginine 3-hydroxylase E CH54_110 cupin superfamily protein K18850 ycfD; 50S ribosomal protein L16 3-hydroxylase [EC:1.14.11.47] E CH54_1232 cupin superfamily protein K18850 ycfD; 50S ribosomal protein L16 3-hydroxylase [EC:1.14.11.47] D 1.14.11.48 xanthine dioxygenase D 1.14.11.49 uridine-5'-phosphate dioxygenase D 1.14.11.51 DNA N6-methyladenine demethylase D 1.14.11.52 validamycin A dioxygenase D 1.14.11.53 mRNA N6-methyladenine demethylase D 1.14.11.54 mRNA N1-methyladenine demethylase D 1.14.11.55 ectoine hydroxylase D 1.14.11.56 L-proline cis-4-hydroxylase D 1.14.11.57 L-proline trans-4-hydroxylase D 1.14.11.58 ornithine lipid ester-linked acyl 2-hydroxylase D 1.14.11.59 2,4-dihydroxy-1,4-benzoxazin-3-one-glucoside dioxygenase D 1.14.11.60 scopoletin 8-hydroxylase D 1.14.11.61 feruloyl-CoA 6-hydroxylase D 1.14.11.62 trans-4-coumaroyl-CoA 2-hydroxylase D 1.14.11.63 peptidyl-lysine (3S)-dioxygenase D 1.14.11.64 glutarate dioxygenase D 1.14.11.65 [histone H3]-dimethyl-L-lysine9 demethylase D 1.14.11.66 [histone H3]-trimethyl-L-lysine9 demethylase D 1.14.11.67 [histone H3]-trimethyl-L-lysine4 demethylase D 1.14.11.68 [histone H3]-trimethyl-L-lysine27 demethylase D 1.14.11.69 [histone H3]-trimethyl-L-lysine36 demethylase D 1.14.11.70 7-deoxycylindrospermopsin hydroxylase D 1.14.11.71 methylphosphonate hydroxylase D 1.14.11.72 [2-(trimethylamino)ethyl]phosphonate dioxygenase D 1.14.11.73 [protein]-arginine 3-hydroxylase D 1.14.11.74 L-isoleucine 31-dioxygenase D 1.14.11.75 31-hydroxy-L-isoleucine 4-dioxygenase D 1.14.11.76 L-glutamate 3(R)-hydroxylase D 1.14.11.77 alkyl sulfatase D 1.14.11.78 (R)-3-[(carboxymethyl)amino]fatty acid dioxygenase/decarboxylase D 1.14.11.79 protein-L-histidine (3S)-3-hydroxylase D 1.14.11.80 methylcytosine dioxygenase D 1.14.11.81 (-)-cyclopenine synthase D 1.14.11.82 5-dehydro-6-demethoxyfumagillol dioxygenase C 1.14.12 With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor D 1.14.12.1 anthranilate 1,2-dioxygenase (deaminating, decarboxylating) D 1.14.12.3 benzene 1,2-dioxygenase D 1.14.12.7 phthalate 4,5-dioxygenase D 1.14.12.8 4-sulfobenzoate 3,4-dioxygenase D 1.14.12.9 4-chlorophenylacetate 3,4-dioxygenase D 1.14.12.10 benzoate 1,2-dioxygenase D 1.14.12.11 toluene dioxygenase D 1.14.12.12 naphthalene 1,2-dioxygenase D 1.14.12.13 2-halobenzoate 1,2-dioxygenase D 1.14.12.14 2-aminobenzenesulfonate 2,3-dioxygenase D 1.14.12.15 terephthalate 1,2-dioxygenase D 1.14.12.16 2-hydroxyquinoline 5,6-dioxygenase D 1.14.12.17 nitric oxide dioxygenase E CH54_1476 globin family protein K05916 hmp; nitric oxide dioxygenase [EC:1.14.12.17] D 1.14.12.18 biphenyl 2,3-dioxygenase D 1.14.12.19 3-phenylpropanoate dioxygenase D 1.14.12.22 carbazole 1,9a-dioxygenase D 1.14.12.23 nitroarene dioxygenase D 1.14.12.24 2,4-dinitrotoluene dioxygenase D 1.14.12.25 p-cumate 2,3-dioxygenase D 1.14.12.26 chlorobenzene dioxygenase C 1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor D 1.14.13.1 salicylate 1-monooxygenase D 1.14.13.2 4-hydroxybenzoate 3-monooxygenase D 1.14.13.4 melilotate 3-monooxygenase D 1.14.13.5 imidazoleacetate 4-monooxygenase D 1.14.13.6 orcinol 2-monooxygenase D 1.14.13.7 phenol 2-monooxygenase (NADPH) D 1.14.13.8 flavin-containing monooxygenase D 1.14.13.9 kynurenine 3-monooxygenase D 1.14.13.10 2,6-dihydroxypyridine 3-monooxygenase D 1.14.13.14 trans-cinnamate 2-monooxygenase D 1.14.13.16 cyclopentanone monooxygenase D 1.14.13.18 4-hydroxyphenylacetate 1-monooxygenase D 1.14.13.19 taxifolin 8-monooxygenase D 1.14.13.20 2,4-dichlorophenol 6-monooxygenase D 1.14.13.22 cyclohexanone monooxygenase D 1.14.13.23 3-hydroxybenzoate 4-monooxygenase D 1.14.13.24 3-hydroxybenzoate 6-monooxygenase D 1.14.13.25 methane monooxygenase (soluble) D 1.14.13.27 4-aminobenzoate 1-monooxygenase D 1.14.13.29 4-nitrophenol 2-monooxygenase D 1.14.13.31 2-nitrophenol 2-monooxygenase D 1.14.13.32 albendazole monooxygenase D 1.14.13.33 4-hydroxybenzoate 3-monooxygenase [NAD(P)H] D 1.14.13.34 leukotriene-E4 20-monooxygenase D 1.14.13.35 anthranilate 3-monooxygenase (deaminating) D 1.14.13.38 anhydrotetracycline 6-monooxygenase D 1.14.13.39 nitric-oxide synthase (NADPH) D 1.14.13.40 anthraniloyl-CoA monooxygenase D 1.14.13.43 questin monooxygenase D 1.14.13.44 2-hydroxybiphenyl 3-monooxygenase D 1.14.13.46 (-)-menthol monooxygenase D 1.14.13.50 pentachlorophenol monooxygenase D 1.14.13.51 6-oxocineole dehydrogenase D 1.14.13.54 ketosteroid monooxygenase D 1.14.13.58 benzoyl-CoA 3-monooxygenase D 1.14.13.59 L-lysine N6-monooxygenase (NADPH) D 1.14.13.61 2-hydroxyquinoline 8-monooxygenase D 1.14.13.62 4-hydroxyquinoline 3-monooxygenase D 1.14.13.63 3-hydroxyphenylacetate 6-hydroxylase D 1.14.13.64 4-hydroxybenzoate 1-hydroxylase D 1.14.13.66 2-hydroxycyclohexanone 2-monooxygenase D 1.14.13.69 alkene monooxygenase D 1.14.13.81 magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase D 1.14.13.82 vanillate monooxygenase D 1.14.13.83 precorrin-3B synthase D 1.14.13.84 4-hydroxyacetophenone monooxygenase D 1.14.13.92 phenylacetone monooxygenase D 1.14.13.101 senecionine N-oxygenase D 1.14.13.105 monocyclic monoterpene ketone monooxygenase D 1.14.13.107 limonene 1,2-monooxygenase D 1.14.13.111 methanesulfonate monooxygenase (NADH) D 1.14.13.113 FAD-dependent urate hydroxylase D 1.14.13.114 6-hydroxynicotinate 3-monooxygenase D 1.14.13.122 chlorophyllide-a oxygenase D 1.14.13.127 3-(3-hydroxyphenyl)propanoate hydroxylase D 1.14.13.128 7-methylxanthine demethylase D 1.14.13.130 pyrrole-2-carboxylate monooxygenase D 1.14.13.131 dissimilatory dimethyl sulfide monooxygenase D 1.14.13.135 1-hydroxy-2-naphthoate hydroxylase D 1.14.13.146 taxoid 14beta-hydroxylase D 1.14.13.148 trimethylamine monooxygenase D 1.14.13.149 phenylacetyl-CoA 1,2-epoxidase D 1.14.13.153 (+)-sabinene 3-hydroxylase D 1.14.13.154 erythromycin 12-hydroxylase D 1.14.13.155 alpha-pinene monooxygenase D 1.14.13.160 (2,2,3-trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA 1,5-monooxygenase D 1.14.13.161 (+)-camphor 6-exo-hydroxylase D 1.14.13.163 6-hydroxy-3-succinoylpyridine 3-monooxygenase D 1.14.13.166 4-nitrocatechol 4-monooxygenase D 1.14.13.167 4-nitrophenol 4-monooxygenase D 1.14.13.168 indole-3-pyruvate monooxygenase D 1.14.13.170 pentalenolactone D synthase D 1.14.13.171 neopentalenolactone D synthase D 1.14.13.172 salicylate 5-hydroxylase D 1.14.13.178 methylxanthine N1-demethylase D 1.14.13.179 methylxanthine N3-demethylase D 1.14.13.180 aklavinone 12-hydroxylase D 1.14.13.181 13-deoxydaunorubicin hydroxylase D 1.14.13.182 2-heptyl-3-hydroxy-4(1H)-quinolone synthase D 1.14.13.187 L-evernosamine nitrososynthase D 1.14.13.189 5-methyl-1-naphthoate 3-hydroxylase D 1.14.13.195 L-ornithine N5-monooxygenase (NADPH) D 1.14.13.196 L-ornithine N5-monooxygenase [NAD(P)H] D 1.14.13.200 tetracenomycin A2 monooxygenase-dioxygenase D 1.14.13.208 benzoyl-CoA 2,3-epoxidase D 1.14.13.209 salicyloyl-CoA 5-hydroxylase D 1.14.13.210 4-methyl-5-nitrocatechol 5-monooxygenase D 1.14.13.211 rifampicin monooxygenase D 1.14.13.212 1,3,7-trimethyluric acid 5-monooxygenase D 1.14.13.215 protoasukamycin 4-monooxygenase D 1.14.13.216 asperlicin C monooxygenase D 1.14.13.217 protodeoxyviolaceinate monooxygenase D 1.14.13.218 5-methylphenazine-1-carboxylate 1-monooxygenase D 1.14.13.219 resorcinol 4-hydroxylase (NADPH) D 1.14.13.220 resorcinol 4-hydroxylase (NADH) D 1.14.13.222 aurachin C monooxygenase/isomerase D 1.14.13.223 3-hydroxy-4-methylanthranilyl-[aryl-carrier protein] 5-monooxygenase D 1.14.13.224 violacein synthase D 1.14.13.225 F-actin monooxygenase D 1.14.13.226 acetone monooxygenase (methyl acetate-forming) D 1.14.13.227 propane 2-monooxygenase D 1.14.13.228 jasmonic acid 12-hydroxylase D 1.14.13.229 tert-butyl alcohol monooxygenase D 1.14.13.230 butane monooxygenase (soluble) D 1.14.13.231 tetracycline 11a-monooxygenase D 1.14.13.232 6-methylpretetramide 4-monooxygenase D 1.14.13.233 4-hydroxy-6-methylpretetramide 12a-monooxygenase D 1.14.13.234 5a,11a-dehydrotetracycline 5-monooxygenase D 1.14.13.235 indole-3-acetate monooxygenase D 1.14.13.236 toluene 4-monooxygenase D 1.14.13.237 aliphatic glucosinolate S-oxygenase D 1.14.13.238 dimethylamine monooxygenase D 1.14.13.239 carnitine monooxygenase D 1.14.13.240 2-polyprenylphenol 6-hydroxylase E CH54_3405 ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein K18800 ubiI; 2-polyprenylphenol 6-hydroxylase [EC:1.14.13.240] D 1.14.13.241 5-pyridoxate monooxygenase D 1.14.13.242 3-hydroxy-2-methylpyridine-5-carboxylate monooxygenase D 1.14.13.243 toluene 2-monooxygenase D 1.14.13.244 phenol 2-monooxygenase (NADH) D 1.14.13.245 assimilatory dimethylsulfide S-monooxygenase D 1.14.13.246 4beta-methylsterol monooxygenase D 1.14.13.247 stachydrine N-demethylase D 1.14.13.248 L-aspartate N-monooxygenase (nitrosuccinate-forming) D 1.14.13.249 3-amino-4-hydroxybenzoate 2-monooxygenase D 1.14.13.250 nitrosourea synthase D 1.14.13.251 glycine betaine monooxygenase C 1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor D 1.14.14.1 unspecific monooxygenase D 1.14.14.3 bacterial luciferase D 1.14.14.5 alkanesulfonate monooxygenase D 1.14.14.8 anthranilate 3-monooxygenase (FAD) D 1.14.14.9 4-hydroxyphenylacetate 3-monooxygenase D 1.14.14.10 nitrilotriacetate monooxygenase D 1.14.14.11 styrene monooxygenase D 1.14.14.12 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione monooxygenase D 1.14.14.13 4-(gamma-L-glutamylamino)butanoyl-[BtrI acyl-carrier protein] monooxygenase D 1.14.14.14 aromatase D 1.14.14.15 (3S)-3-amino-3-(3-chloro-4-hydroxyphenyl)propanoyl-[peptidyl-carrier protein SgcC2] monooxygenase D 1.14.14.16 steroid 21-monooxygenase D 1.14.14.17 squalene monooxygenase D 1.14.14.18 heme oxygenase (biliverdin-producing) D 1.14.14.19 steroid 17alpha-monooxygenase D 1.14.14.20 phenol 2-monooxygenase (FADH2) D 1.14.14.21 dibenzothiophene monooxygenase D 1.14.14.22 dibenzothiophene sulfone monooxygenase D 1.14.14.23 cholesterol 7alpha-monooxygenase D 1.14.14.24 vitamin D 25-hydroxylase D 1.14.14.25 cholesterol 24-hydroxylase D 1.14.14.26 24-hydroxycholesterol 7alpha-hydroxylase D 1.14.14.27 resorcinol 4-hydroxylase (FADH2) D 1.14.14.28 long-chain alkane monooxygenase D 1.14.14.29 25/26-hydroxycholesterol 7alpha-hydroxylase D 1.14.14.30 isobutylamine N-monooxygenase D 1.14.14.31 ipsdienol synthase D 1.14.14.32 17alpha-hydroxyprogesterone deacetylase D 1.14.14.33 ethylenediaminetetraacetate monooxygenase D 1.14.14.34 methanesulfonate monooxygenase (FMNH2) D 1.14.14.35 dimethylsulfone monooxygenase D 1.14.14.36 tyrosine N-monooxygenase D 1.14.14.37 4-hydroxyphenylacetaldehyde oxime monooxygenase D 1.14.14.38 valine N-monooxygenase D 1.14.14.39 isoleucine N-monooxygenase D 1.14.14.40 phenylalanine N-monooxygenase D 1.14.14.41 (E)-2-methylbutanal oxime monooxygenase D 1.14.14.42 homomethionine N-monooxygenase D 1.14.14.43 (methylsulfanyl)alkanaldoxime N-monooxygenase D 1.14.14.44 phenylacetaldehyde oxime monooxygenase D 1.14.14.45 aromatic aldoxime N-monooxygenase D 1.14.14.46 pimeloyl-[acyl-carrier protein] synthase D 1.14.14.47 nitric-oxide synthase (flavodoxin) D 1.14.14.48 jasmonoyl-L-amino acid 12-hydroxylase D 1.14.14.49 12-hydroxyjasmonoyl-L-amino acid 12-hydroxylase D 1.14.14.50 tabersonine 3-oxygenase D 1.14.14.51 (S)-limonene 6-monooxygenase D 1.14.14.52 (S)-limonene 7-monooxygenase D 1.14.14.53 (R)-limonene 6-monooxygenase D 1.14.14.54 phenylacetate 2-hydroxylase D 1.14.14.55 quinine 3-monooxygenase D 1.14.14.56 1,8-cineole 2-exo-monooxygenase D 1.14.14.57 taurochenodeoxycholate 6alpha-hydroxylase D 1.14.14.58 trimethyltridecatetraene synthase D 1.14.14.59 dimethylnonatriene synthase D 1.14.14.60 ferruginol monooxygenase D 1.14.14.61 carnosic acid synthase D 1.14.14.62 salviol synthase D 1.14.14.63 beta-amyrin 16beta-monooxygenase D 1.14.14.64 beta-amyrin 6beta-monooxygenase D 1.14.14.65 sugiol synthase D 1.14.14.66 marmesin synthase D 1.14.14.67 11-hydroxysugiol 20-monooxygenase D 1.14.14.68 syn-pimaradiene 3-monooxygenase D 1.14.14.69 ent-cassadiene hydroxylase D 1.14.14.70 ent-sandaracopimaradiene 3-hydroxylase D 1.14.14.71 cucurbitadienol 11-hydroxylase D 1.14.14.72 drimenol monooxygenase D 1.14.14.73 albendazole monooxygenase (sulfoxide-forming) D 1.14.14.74 albendazole monooxygenase (hydroxylating) D 1.14.14.75 fenbendazole monooxygenase (4'-hydroxylating) D 1.14.14.76 ent-isokaurene C2/C3-hydroxylase D 1.14.14.77 phenylacetonitrile alpha-monooxygenase D 1.14.14.78 phylloquinone omega-hydroxylase D 1.14.14.79 docosahexaenoic acid omega-hydroxylase D 1.14.14.80 long-chain fatty acid omega-monooxygenase D 1.14.14.81 flavanoid 3',5'-hydroxylase D 1.14.14.82 flavonoid 3'-monooxygenase D 1.14.14.83 geraniol 8-hydroxylase D 1.14.14.84 linalool 8-monooxygenase D 1.14.14.85 7-deoxyloganate 7-hydroxylase D 1.14.14.86 ent-kaurene monooxygenase D 1.14.14.87 2-hydroxyisoflavanone synthase D 1.14.14.88 isoflavone 3'-hydroxylase D 1.14.14.89 4'-methoxyisoflavone 2'-hydroxylase D 1.14.14.90 isoflavone 2'-hydroxylase D 1.14.14.91 trans-cinnamate 4-monooxygenase D 1.14.14.92 benzoate 4-monooxygenase D 1.14.14.93 3,9-dihydroxypterocarpan 6a-monooxygenase D 1.14.14.94 leukotriene-B4 20-monooxygenase D 1.14.14.95 germacrene A hydroxylase D 1.14.14.96 5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase D 1.14.14.97 methyltetrahydroprotoberberine 14-monooxygenase D 1.14.14.98 protopine 6-monooxygenase D 1.14.14.99 (S)-limonene 3-monooxygenase D 1.14.14.100 dihydrosanguinarine 10-monooxygenase D 1.14.14.101 dihydrochelirubine 12-monooxygenase D 1.14.14.102 N-methylcoclaurine 3'-monooxygenase D 1.14.14.103 tabersonine 16-hydroxylase D 1.14.14.104 vinorine hydroxylase D 1.14.14.105 taxane 10beta-hydroxylase D 1.14.14.106 taxane 13alpha-hydroxylase D 1.14.14.107 ent-kaurenoic acid monooxygenase D 1.14.14.108 2,5-diketocamphane 1,2-monooxygenase D 1.14.14.109 3-hydroxyindolin-2-one monooxygenase D 1.14.14.110 2-hydroxy-1,4-benzoxazin-3-one monooxygenase D 1.14.14.111 9beta-pimara-7,15-diene oxidase D 1.14.14.112 ent-cassa-12,15-diene 11-hydroxylase D 1.14.14.113 alpha-humulene 10-hydroxylase D 1.14.14.114 amorpha-4,11-diene 12-monooxygenase D 1.14.14.115 11-oxo-beta-amyrin 30-oxidase D 1.14.14.116 averantin hydroxylase D 1.14.14.117 aflatoxin B synthase D 1.14.14.118 tryprostatin B 6-hydroxylase D 1.14.14.119 fumitremorgin C monooxygenase D 1.14.14.120 dammarenediol 12-hydroxylase D 1.14.14.121 protopanaxadiol 6-hydroxylase D 1.14.14.122 oryzalexin E synthase D 1.14.14.123 oryzalexin D synthase D 1.14.14.124 dihydromonacolin L hydroxylase D 1.14.14.125 monacolin L hydroxylase D 1.14.14.126 beta-amyrin 28-monooxygenase D 1.14.14.127 methyl farnesoate epoxidase D 1.14.14.128 farnesoate epoxidase D 1.14.14.129 long-chain acyl-CoA omega-monooxygenase D 1.14.14.130 laurate 7-monooxygenase D 1.14.14.131 bursehernin 5'-monooxygenase D 1.14.14.132 (-)-4'-demethyl-deoxypodophyllotoxin 4-hydroxylase D 1.14.14.133 1,8-cineole 2-endo-monooxygenase D 1.14.14.134 beta-amyrin 24-hydroxylase D 1.14.14.135 glyceollin synthase D 1.14.14.136 deoxysarpagine hydroxylase D 1.14.14.137 (+)-abscisic acid 8'-hydroxylase D 1.14.14.138 lithocholate 6beta-hydroxylase D 1.14.14.139 5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase D 1.14.14.141 psoralen synthase D 1.14.14.142 8-dimethylallylnaringenin 2'-hydroxylase D 1.14.14.143 (+)-menthofuran synthase D 1.14.14.144 abieta-7,13-diene hydroxylase D 1.14.14.145 abieta-7,13-dien-18-ol hydroxylase D 1.14.14.146 geranylgeraniol 18-hydroxylase D 1.14.14.147 22alpha-hydroxysteroid 23-monooxygenase D 1.14.14.148 angelicin synthase D 1.14.14.149 5-epiaristolochene 1,3-dihydroxylase D 1.14.14.150 costunolide synthase D 1.14.14.151 premnaspirodiene oxygenase D 1.14.14.152 beta-amyrin 11-oxidase D 1.14.14.153 indole-2-monooxygenase D 1.14.14.154 sterol 14alpha-demethylase D 1.14.14.155 3,6-diketocamphane 1,2-monooxygenase D 1.14.14.156 tryptophan N-monooxygenase D 1.14.14.157 indolin-2-one monooxygenase D 1.14.14.158 carotenoid epsilon hydroxylase D 1.14.14.159 dolabradiene monooxygenase D 1.14.14.160 zealexin A1 synthase D 1.14.14.161 nepetalactol monooxygenase D 1.14.14.162 flavanone 2-hydroxylase D 1.14.14.163 (S)-1-hydroxy-N-methylcanadine 13-hydroxylase D 1.14.14.164 fraxetin 5-hydroxylase D 1.14.14.165 indole-3-carbonyl nitrile 4-hydroxylase D 1.14.14.166 (S)-N-methylcanadine 1-hydroxylase D 1.14.14.167 (13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine 8-hydroxylase D 1.14.14.168 germacrene A acid 8beta-hydroxylase D 1.14.14.169 eupatolide synthase D 1.14.14.170 8-epi-inunolide synthase D 1.14.14.171 beta-amyrin 16alpha-hydroxylase D 1.14.14.172 3,5,6-trichloropyridin-2-ol monooxygenase D 1.14.14.173 2,4,6-trichlorophenol monooxygenase D 1.14.14.174 geranylhydroquinone 3''-hydroxylase D 1.14.14.175 ferruginol synthase D 1.14.14.176 taxadiene 5alpha-hydroxylase D 1.14.14.177 ultra-long-chain fatty acid omega-hydroxylase D 1.14.14.178 steroid 22S-hydroxylase D 1.14.14.179 brassinosteroid 6-oxygenase D 1.14.14.180 brassinolide synthase D 1.14.14.181 sulfoquinovose monooxygenase D 1.14.14.182 taxoid 7beta-hydroxylase D 1.14.14.183 taxoid 2alpha-hydroxylase D 1.14.14.184 5-dehydro-6-demethoxyfumagillol synthase C 1.14.15 With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor D 1.14.15.1 camphor 5-monooxygenase D 1.14.15.3 alkane 1-monooxygenase D 1.14.15.4 steroid 11beta-monooxygenase D 1.14.15.5 corticosterone 18-monooxygenase D 1.14.15.6 cholesterol monooxygenase (side-chain-cleaving) D 1.14.15.7 choline monooxygenase D 1.14.15.8 steroid 15beta-monooxygenase D 1.14.15.9 spheroidene monooxygenase D 1.14.15.10 (+)-camphor 6-endo-hydroxylase D 1.14.15.11 pentalenic acid synthase D 1.14.15.13 pulcherriminic acid synthase D 1.14.15.14 methyl-branched lipid omega-hydroxylase D 1.14.15.15 cholestanetriol 26-monooxygenase D 1.14.15.16 vitamin D3 24-hydroxylase D 1.14.15.17 pheophorbide a oxygenase D 1.14.15.18 calcidiol 1-monooxygenase D 1.14.15.19 C-19 steroid 1alpha-hydroxylase D 1.14.15.20 heme oxygenase (biliverdin-producing, ferredoxin) D 1.14.15.21 zeaxanthin epoxidase D 1.14.15.22 vitamin D 1,25-hydroxylase D 1.14.15.23 chloroacetanilide N-alkylformylase D 1.14.15.24 beta-carotene 3-hydroxylase D 1.14.15.25 p-cymene methyl-monooxygenase D 1.14.15.26 toluene methyl-monooxygenase D 1.14.15.27 beta-dihydromenaquinone-9 omega-hydroxylase D 1.14.15.28 cholest-4-en-3-one 26-monooxygenase [(25R)-3-oxocholest-4-en-26-oate forming] D 1.14.15.29 cholest-4-en-3-one 26-monooxygenase [(25S)-3-oxocholest-4-en-26-oate forming] D 1.14.15.30 3-ketosteroid 9alpha-monooxygenase D 1.14.15.31 2-hydroxy-5-methyl-1-naphthoate 7-hydroxylase D 1.14.15.32 pentalenene oxygenase D 1.14.15.33 pikromycin synthase D 1.14.15.34 20-oxo-5-O-mycaminosyltylactone 23-monooxygenase D 1.14.15.35 6-deoxyerythronolide B hydroxylase D 1.14.15.36 sterol 14alpha-demethylase (ferredoxin) D 1.14.15.37 luteothin monooxygenase D 1.14.15.38 N,N-dimethyl phenylurea N-demethylase D 1.14.15.39 epi-isozizaene 5-monooxygenase C 1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor D 1.14.16.1 phenylalanine 4-monooxygenase D 1.14.16.2 tyrosine 3-monooxygenase D 1.14.16.4 tryptophan 5-monooxygenase D 1.14.16.5 alkylglycerol monooxygenase D 1.14.16.6 mandelate 4-monooxygenase D 1.14.16.7 phenylalanine 3-monooxygenase C 1.14.17 With reduced ascorbate as one donor, and incorporation of one atom of oxygen into the other donor D 1.14.17.1 dopamine beta-monooxygenase D 1.14.17.3 peptidylglycine monooxygenase D 1.14.17.4 aminocyclopropanecarboxylate oxidase C 1.14.18 With another compound as one donor, and incorporation of one atom of oxygen into the other donor D 1.14.18.1 tyrosinase D 1.14.18.2 CMP-N-acetylneuraminate monooxygenase D 1.14.18.3 methane monooxygenase (particulate) D 1.14.18.4 phosphatidylcholine 12-monooxygenase D 1.14.18.5 sphingolipid C4-monooxygenase D 1.14.18.6 4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase D 1.14.18.7 dihydroceramide fatty acyl 2-hydroxylase D 1.14.18.9 4alpha-methylsterol monooxygenase D 1.14.18.10 plant 4,4-dimethylsterol C-4alpha-methyl-monooxygenase D 1.14.18.11 plant 4alpha-monomethylsterol monooxygenase D 1.14.18.12 2-hydroxy fatty acid dioxygenase C 1.14.19 With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water D 1.14.19.1 stearoyl-CoA 9-desaturase D 1.14.19.2 stearoyl-[acyl-carrier-protein] 9-desaturase D 1.14.19.3 acyl-CoA 6-desaturase D 1.14.19.4 acyl-lipid (11-3)-desaturase D 1.14.19.5 acyl-CoA 11-(Z)-desaturase D 1.14.19.6 acyl-CoA (9+3)-desaturase D 1.14.19.8 pentalenolactone synthase D 1.14.19.9 tryptophan 7-halogenase D 1.14.19.10 icosanoyl-CoA 5-desaturase D 1.14.19.11 acyl-[acyl-carrier-protein] 4-desaturase D 1.14.19.12 acyl-lipid omega-(9-4) desaturase D 1.14.19.13 acyl-CoA 15-desaturase D 1.14.19.14 linoleoyl-lipid Delta9 conjugase D 1.14.19.15 (11Z)-hexadec-11-enoyl-CoA conjugase D 1.14.19.16 linoleoyl-lipid Delta12 conjugase (11E,13Z-forming) D 1.14.19.17 sphingolipid 4-desaturase D 1.14.19.18 sphingolipid 8-(E)-desaturase D 1.14.19.19 sphingolipid 10-desaturase D 1.14.19.20 Delta7-sterol 5(6)-desaturase D 1.14.19.21 cholesterol 7-desaturase D 1.14.19.22 acyl-lipid omega-6 desaturase (cytochrome b5) D 1.14.19.23 acyl-lipid (n+3)-(Z)-desaturase (ferredoxin) D 1.14.19.24 acyl-CoA 11-(E)-desaturase D 1.14.19.25 acyl-lipid omega-3 desaturase (cytochrome b5) D 1.14.19.26 acyl-[acyl-carrier-protein] 6-desaturase D 1.14.19.27 sn-2 palmitoyl-lipid 9-desaturase D 1.14.19.28 sn-1 stearoyl-lipid 9-desaturase D 1.14.19.29 sphingolipid 8-(E/Z)-desaturase D 1.14.19.30 acyl-lipid (8-3)-desaturase D 1.14.19.31 acyl-lipid (7-3)-desaturase D 1.14.19.32 palmitoyl-CoA 14-(E/Z)-desaturase D 1.14.19.33 Delta12 acyl-lipid conjugase (11E,13E-forming) D 1.14.19.34 acyl-lipid (9+3)-(E)-desaturase D 1.14.19.35 sn-2 acyl-lipid omega-3 desaturase (ferredoxin) D 1.14.19.36 sn-1 acyl-lipid omega-3 desaturase (ferredoxin) D 1.14.19.37 acyl-CoA 5-desaturase D 1.14.19.38 acyl-lipid Delta6-acetylenase D 1.14.19.39 acyl-lipid Delta12-acetylenase D 1.14.19.40 hex-5-enoyl-[acyl-carrier protein] acetylenase D 1.14.19.41 sterol 22-desaturase D 1.14.19.42 palmitoyl-[glycerolipid] 7-desaturase D 1.14.19.43 palmitoyl-[glycerolipid] 3-(E)-desaturase D 1.14.19.44 acyl-CoA (8-3)-desaturase D 1.14.19.45 sn-1 oleoyl-lipid 12-desaturase D 1.14.19.46 sn-1 linoleoyl-lipid 6-desaturase D 1.14.19.47 acyl-lipid (9-3)-desaturase D 1.14.19.48 tert-amyl alcohol desaturase D 1.14.19.49 tetracycline 7-halogenase D 1.14.19.50 noroxomaritidine synthase D 1.14.19.51 (S)-corytuberine synthase D 1.14.19.52 camalexin synthase D 1.14.19.53 all-trans-retinol 3,4-desaturase D 1.14.19.54 1,2-dehydroreticuline synthase D 1.14.19.55 4-hydroxybenzoate brominase (decarboxylating) D 1.14.19.56 1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] chlorinase D 1.14.19.57 1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] brominase D 1.14.19.58 tryptophan 5-halogenase D 1.14.19.59 tryptophan 6-halogenase D 1.14.19.60 7-chloro-L-tryptophan 6-halogenase D 1.14.19.61 dihydrorhizobitoxine desaturase D 1.14.19.62 secologanin synthase D 1.14.19.63 pseudobaptigenin synthase D 1.14.19.64 (S)-stylopine synthase D 1.14.19.65 (S)-cheilanthifoline synthase D 1.14.19.66 berbamunine synthase D 1.14.19.67 salutaridine synthase D 1.14.19.68 (S)-canadine synthase D 1.14.19.69 biflaviolin synthase D 1.14.19.70 mycocyclosin synthase D 1.14.19.71 fumitremorgin C synthase D 1.14.19.72 (-)-pluviatolide synthase D 1.14.19.73 (S)-nandinine synthase D 1.14.19.74 (+)-piperitol/(+)-sesamin synthase D 1.14.19.75 very-long-chain acyl-lipid omega-9 desaturase D 1.14.19.76 flavone synthase II D 1.14.19.77 plasmanylethanolamine desaturase D 1.14.19.78 decanoyl-[acyl-carrier protein] acetylenase D 1.14.19.79 3beta,22alpha-dihydroxysteroid 3-dehydrogenase C 1.14.20 With 2-oxoglutarate as one donor, and the other dehydrogenated D 1.14.20.1 deacetoxycephalosporin-C synthase D 1.14.20.3 (5R)-carbapenem-3-carboxylate synthase D 1.14.20.4 anthocyanidin synthase D 1.14.20.5 flavone synthase I D 1.14.20.6 flavonol synthase D 1.14.20.7 2-oxoglutarate/L-arginine monooxygenase/decarboxylase (succinate-forming) D 1.14.20.8 (-)-deoxypodophyllotoxin synthase D 1.14.20.9 L-tyrosine isonitrile desaturase D 1.14.20.10 L-tyrosine isonitrile desaturase/decarboxylase D 1.14.20.11 3-[(Z)-2-isocyanoethenyl]-1H-indole synthase D 1.14.20.12 3-[(E)-2-isocyanoethenyl]-1H-indole synthase D 1.14.20.13 6beta-hydroxyhyoscyamine epoxidase D 1.14.20.14 hapalindole-type alkaloid chlorinase D 1.14.20.15 L-threonyl-[L-threonyl-carrier protein] 4-chlorinase C 1.14.99 Miscellaneous D 1.14.99.1 prostaglandin-endoperoxide synthase D 1.14.99.2 kynurenine 7,8-hydroxylase D 1.14.99.4 progesterone monooxygenase D 1.14.99.11 estradiol 6beta-monooxygenase D 1.14.99.12 androst-4-ene-3,17-dione monooxygenase D 1.14.99.14 progesterone 11alpha-monooxygenase D 1.14.99.15 4-methoxybenzoate monooxygenase (O-demethylating) D 1.14.99.20 phylloquinone monooxygenase (2,3-epoxidizing) D 1.14.99.21 Latia-luciferin monooxygenase (demethylating) D 1.14.99.22 ecdysone 20-monooxygenase D 1.14.99.23 3-hydroxybenzoate 2-monooxygenase D 1.14.99.24 steroid 9alpha-monooxygenase D 1.14.99.26 2-hydroxypyridine 5-monooxygenase D 1.14.99.29 deoxyhypusine monooxygenase D 1.14.99.34 monoprenyl isoflavone epoxidase D 1.14.99.35 thiophene-2-carbonyl-CoA monooxygenase D 1.14.99.38 cholesterol 25-monooxygenase D 1.14.99.39 ammonia monooxygenase D 1.14.99.44 diapolycopene oxygenase D 1.14.99.46 pyrimidine oxygenase D 1.14.99.47 (+)-larreatricin hydroxylase D 1.14.99.48 heme oxygenase (staphylobilin-producing) D 1.14.99.50 gamma-glutamyl hercynylcysteine S-oxide synthase D 1.14.99.52 L-cysteinyl-L-histidinylsulfoxide synthase D 1.14.99.53 lytic chitin monooxygenase D 1.14.99.54 lytic cellulose monooxygenase (C1-hydroxylating) D 1.14.99.55 lytic starch monooxygenase D 1.14.99.56 lytic cellulose monooxygenase (C4-dehydrogenating) D 1.14.99.57 heme oxygenase (mycobilin-producing) D 1.14.99.58 heme oxygenase (biliverdin-IX-beta and delta-forming) D 1.14.99.59 tryptamine 4-monooxygenase D 1.14.99.60 3-demethoxyubiquinol 3-hydroxylase E CH54_1195 ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein K03184 ubiF; 3-demethoxyubiquinol 3-hydroxylase [EC:1.14.99.60] D 1.14.99.61 cyclooctat-9-en-7-ol 5-monooxygenase D 1.14.99.62 cyclooctatin synthase D 1.14.99.63 beta-carotene 4-ketolase D 1.14.99.64 zeaxanthin 4-ketolase D 1.14.99.65 4-amino-L-phenylalanyl-[CmlP-peptidyl-carrier-protein] 3-hydroxylase D 1.14.99.66 [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase D 1.14.99.67 alpha-N-dichloroacetyl-p-aminophenylserinol N-oxygenase D 1.14.99.68 4-aminobenzoate N-oxygenase D 1.14.99.69 tRNA 2-(methylsulfanyl)-N6-isopentenyladenosine37 hydroxylase B 1.15 Acting on superoxide as acceptor C 1.15.1 Acting on superoxide as acceptor (only sub-subclass identified to date) D 1.15.1.1 superoxide dismutase E CH54_302 iron/manganese superoxide dismutase, alpha-hairpin domain protein K04564 SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1] E CH54_2462 iron/manganese superoxide dismutase, alpha-hairpin domain protein K04564 SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1] E CH54_1702 copper/zinc superoxide dismutase family protein K04565 SOD1; superoxide dismutase, Cu-Zn family [EC:1.15.1.1] D 1.15.1.2 superoxide reductase B 1.16 Oxidizing metal ions C 1.16.1 With NAD+ or NADP+ as acceptor D 1.16.1.1 mercury(II) reductase D 1.16.1.2 diferric-transferrin reductase D 1.16.1.6 cyanocobalamin reductase D 1.16.1.7 ferric-chelate reductase (NADH) D 1.16.1.8 [methionine synthase] reductase D 1.16.1.9 ferric-chelate reductase (NADPH) D 1.16.1.10 ferric-chelate reductase [NAD(P)H] C 1.16.3 With oxygen as acceptor D 1.16.3.1 ferroxidase E CH54_2255 bfr; bacterioferritin K03594 bfr; bacterioferritin [EC:1.16.3.1] D 1.16.3.2 bacterial non-heme ferritin E CH54_179 ferritin-like domain protein K02217 ftnA; ferritin [EC:1.16.3.2] D 1.16.3.3 manganese oxidase D 1.16.3.4 cuproxidase E CH54_1741 multicopper oxidase family protein K14588 cueO; cuproxidase [EC:1.16.3.4] C 1.16.9 With a copper protein as acceptor D 1.16.9.1 iron:rusticyanin reductase C 1.16.99 With unknown physiological acceptors D 1.16.99.1 [Co(II) methylated amine-specific corrinoid protein] reductase B 1.17 Acting on CH or CH2 groups C 1.17.1 With NAD+ or NADP+ as acceptor D 1.17.1.1 CDP-4-dehydro-6-deoxyglucose reductase D 1.17.1.3 leucoanthocyanidin reductase D 1.17.1.4 xanthine dehydrogenase D 1.17.1.5 nicotinate dehydrogenase D 1.17.1.8 4-hydroxy-tetrahydrodipicolinate reductase E CH54_1828 dapB; 4-hydroxy-tetrahydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8] D 1.17.1.9 formate dehydrogenase E CH54_2459 fdnG; formate dehydrogenase-N alpha subunit K00123 fdoG; formate dehydrogenase major subunit [EC:1.17.1.9] E CH54_2460 molybdopterin oxidoreductase Fe4S4 domain protein K00123 fdoG; formate dehydrogenase major subunit [EC:1.17.1.9] D 1.17.1.10 formate dehydrogenase (NADP+) D 1.17.1.11 formate dehydrogenase (NAD+, ferredoxin) C 1.17.2 With a cytochrome as acceptor D 1.17.2.1 nicotinate dehydrogenase (cytochrome) D 1.17.2.2 lupanine 17-hydroxylase (cytochrome c) D 1.17.2.3 formate dehydrogenase (cytochrome-c-553) C 1.17.3 With oxygen as acceptor D 1.17.3.1 pteridine oxidase D 1.17.3.2 xanthine oxidase D 1.17.3.3 6-hydroxynicotinate dehydrogenase D 1.17.3.4 juglone 3-hydroxylase C 1.17.4 With a disulfide as acceptor D 1.17.4.1 ribonucleoside-diphosphate reductase E CH54_1579 ribonucleoside-diphosphate reductase, alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] E CH54_3963 ribonucleoside-diphosphate reductase, alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] E CH54_3962 ribonucleotide reductase, small chain family protein K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] E CH54_1580 ribonucleotide reductase, small chain family protein K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D 1.17.4.2 ribonucleoside-triphosphate reductase (thioredoxin) D 1.17.4.4 vitamin-K-epoxide reductase (warfarin-sensitive) D 1.17.4.5 vitamin-K-epoxide reductase (warfarin-insensitive) C 1.17.5 With a quinone or similar compound as acceptor D 1.17.5.1 phenylacetyl-CoA dehydrogenase D 1.17.5.2 caffeine dehydrogenase D 1.17.5.3 formate dehydrogenase-N C 1.17.7 With an iron-sulfur protein as acceptor D 1.17.7.1 (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (ferredoxin) E CH54_1449 ispG; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase K03526 gcpE; (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase [EC:1.17.7.1 1.17.7.3] D 1.17.7.2 7-hydroxymethyl chlorophyll a reductase D 1.17.7.3 (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (flavodoxin) E CH54_1449 ispG; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase K03526 gcpE; (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase [EC:1.17.7.1 1.17.7.3] D 1.17.7.4 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase E CH54_1829 ispH; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase K03527 ispH; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase [EC:1.17.7.4] C 1.17.8 With a flavin as acceptor D 1.17.8.1 hydroxysqualene dehydroxylase C 1.17.9 With a copper protein as acceptor D 1.17.9.1 4-methylphenol dehydrogenase (hydroxylating) D 1.17.9.2 (+)-pinoresinol hydroxylase C 1.17.98 With other, known, physiological acceptors D 1.17.98.2 bacteriochlorophyllide c C-71-hydroxylase D 1.17.98.3 formate dehydrogenase (coenzyme F420) D 1.17.98.4 formate dehydrogenase (hydrogenase) E CH54_2070 formate dehydrogenase, alpha subunit K22015 fdhF; formate dehydrogenase (hydrogenase) [EC:1.17.98.4 1.17.98.-] E CH54_1020 formate dehydrogenase, alpha subunit K22015 fdhF; formate dehydrogenase (hydrogenase) [EC:1.17.98.4 1.17.98.-] C 1.17.99 With unknown physiological acceptors D 1.17.99.2 ethylbenzene hydroxylase D 1.17.99.3 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase D 1.17.99.4 uracil/thymine dehydrogenase D 1.17.99.6 epoxyqueuosine reductase E CH54_2044 queG; epoxyqueuosine reductase K18979 queG; epoxyqueuosine reductase [EC:1.17.99.6] D 1.17.99.8 limonene dehydrogenase D 1.17.99.9 heme a synthase D 1.17.99.10 steroid C-25 hydroxylase D 1.17.99.11 3-oxo-Delta1-steroid hydratase/dehydrogenase B 1.18 Acting on iron-sulfur proteins as donors C 1.18.1 With NAD+ or NADP+ as acceptor D 1.18.1.1 rubredoxin---NAD+ reductase D 1.18.1.2 ferredoxin---NADP+ reductase E CH54_2677 oxidoreductase NAD-binding domain protein K00528 fpr; ferredoxin/flavodoxin---NADP+ reductase [EC:1.18.1.2 1.19.1.1] D 1.18.1.3 ferredoxin---NAD+ reductase D 1.18.1.4 rubredoxin---NAD(P)+ reductase D 1.18.1.5 putidaredoxin---NAD+ reductase D 1.18.1.6 adrenodoxin-NADP+ reductase D 1.18.1.7 ferredoxin---NAD(P)+ reductase (naphthalene dioxygenase ferredoxin-specific) C 1.18.6 With dinitrogen as acceptor D 1.18.6.1 nitrogenase D 1.18.6.2 vanadium-dependent nitrogenase B 1.19 Acting on reduced flavodoxin as donor C 1.19.1 With NAD+ or NADP+ as acceptor D 1.19.1.1 flavodoxin---NADP+ reductase E CH54_2677 oxidoreductase NAD-binding domain protein K00528 fpr; ferredoxin/flavodoxin---NADP+ reductase [EC:1.18.1.2 1.19.1.1] C 1.19.6 With dinitrogen as acceptor D 1.19.6.1 nitrogenase (flavodoxin) B 1.20 Acting on phosphorus or arsenic in donors C 1.20.1 With NAD+ or NADP+ as acceptor D 1.20.1.1 phosphonate dehydrogenase C 1.20.2 With a cytochrome as acceptor D 1.20.2.1 arsenate reductase (cytochrome c) C 1.20.4 With disulfide as acceptor D 1.20.4.1 arsenate reductase (glutathione/glutaredoxin) E CH54_1350 arsC; arsenate reductase K00537 arsC; arsenate reductase (glutaredoxin) [EC:1.20.4.1] E CH54_422 arsC; arsenate reductase K00537 arsC; arsenate reductase (glutaredoxin) [EC:1.20.4.1] D 1.20.4.2 methylarsonate reductase D 1.20.4.3 mycoredoxin D 1.20.4.4 arsenate reductase (thioredoxin) C 1.20.9 With a copper protein as acceptor D 1.20.9.1 arsenate reductase (azurin) C 1.20.99 With unknown physiological acceptors D 1.20.99.1 arsenate reductase (donor) B 1.21 Catalysing the reaction X-H + Y-H = X-Y C 1.21.1 With NAD+ or NADP+ as acceptor D 1.21.1.1 iodotyrosine deiodinase D 1.21.1.2 2,4-dichlorobenzoyl-CoA reductase C 1.21.3 With oxygen as acceptor D 1.21.3.1 isopenicillin-N synthase D 1.21.3.2 columbamine oxidase D 1.21.3.3 reticuline oxidase D 1.21.3.4 sulochrin oxidase [(+)-bisdechlorogeodin-forming] D 1.21.3.5 sulochrin oxidase [(-)-bisdechlorogeodin-forming] D 1.21.3.6 aureusidin synthase D 1.21.3.7 tetrahydrocannabinolic acid synthase D 1.21.3.8 cannabidiolic acid synthase D 1.21.3.10 hercynylcysteine S-oxide synthase C 1.21.4 With a disulfide as acceptor D 1.21.4.1 D-proline reductase D 1.21.4.2 glycine reductase D 1.21.4.3 sarcosine reductase D 1.21.4.4 betaine reductase D 1.21.4.5 tetrachlorohydroquinone reductive dehalogenase C 1.21.98 With other, known, physiological acceptors D 1.21.98.1 cyclic dehypoxanthinyl futalosine synthase D 1.21.98.2 dichlorochromopyrrolate synthase D 1.21.98.3 anaerobic magnesium-protoporphyrin IX monomethyl ester cyclase D 1.21.98.4 PqqA peptide cyclase D 1.21.98.5 tetraether lipid synthase C 1.21.99 With unknown physiological acceptors D 1.21.99.1 beta-cyclopiazonate dehydrogenase D 1.21.99.3 thyroxine 5-deiodinase D 1.21.99.4 thyroxine 5'-deiodinase D 1.21.99.5 tetrachloroethene reductive dehalogenase B 1.23 Reducing C-O-C group as acceptor C 1.23.1 With NADH or NADPH as donor D 1.23.1.1 (+)-pinoresinol reductase D 1.23.1.2 (+)-lariciresinol reductase D 1.23.1.3 (-)-pinoresinol reductase D 1.23.1.4 (-)-lariciresinol reductase C 1.23.5 With a quinone or similar compound as acceptor D 1.23.5.1 violaxanthin de-epoxidase B 1.97 Other oxidoreductases C 1.97.1 Sole sub-subclass for oxidoreductases that do not belong in the other subclasses D 1.97.1.1 chlorate reductase D 1.97.1.2 pyrogallol hydroxytransferase D 1.97.1.4 [formate-C-acetyltransferase]-activating enzyme E CH54_1944 4Fe-4S single cluster domain protein K04068 nrdG; anaerobic ribonucleoside-triphosphate reductase activating protein [EC:1.97.1.4] E CH54_4086 pflA; pyruvate formate-lyase 1-activating enzyme K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4] E CH54_1804 glycyl-radical enzyme activating family protein K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4] D 1.97.1.9 selenate reductase D 1.97.1.12 photosystem I # A2. Transferases B 2.1 Transferring one-carbon groups C 2.1.1 Methyltransferases D 2.1.1.1 nicotinamide N-methyltransferase D 2.1.1.2 guanidinoacetate N-methyltransferase D 2.1.1.3 thetin---homocysteine S-methyltransferase D 2.1.1.4 acetylserotonin O-methyltransferase D 2.1.1.5 betaine---homocysteine S-methyltransferase D 2.1.1.6 catechol O-methyltransferase D 2.1.1.7 nicotinate N-methyltransferase D 2.1.1.8 histamine N-methyltransferase D 2.1.1.9 thiol S-methyltransferase D 2.1.1.10 homocysteine S-methyltransferase D 2.1.1.11 magnesium protoporphyrin IX methyltransferase D 2.1.1.12 methionine S-methyltransferase D 2.1.1.13 methionine synthase E CH54_2909 metH; methionine synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13] D 2.1.1.14 5-methyltetrahydropteroyltriglutamate---homocysteine S-methyltransferase E CH54_2833 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14] D 2.1.1.15 fatty-acid O-methyltransferase D 2.1.1.16 methylene-fatty-acyl-phospholipid synthase D 2.1.1.17 phosphatidylethanolamine N-methyltransferase D 2.1.1.18 polysaccharide O-methyltransferase D 2.1.1.19 trimethylsulfonium---tetrahydrofolate N-methyltransferase D 2.1.1.20 glycine N-methyltransferase D 2.1.1.21 methylamine---glutamate N-methyltransferase D 2.1.1.22 carnosine N-methyltransferase D 2.1.1.25 phenol O-methyltransferase D 2.1.1.26 iodophenol O-methyltransferase D 2.1.1.27 tyramine N-methyltransferase D 2.1.1.28 phenylethanolamine N-methyltransferase D 2.1.1.33 tRNA (guanine46-N7)-methyltransferase E CH54_3362 trmB; tRNA (guanine-N(7)-)-methyltransferase K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33] D 2.1.1.34 tRNA (guanosine18-2'-O)-methyltransferase E CH54_2579 spoU rRNA Methylase family protein K00556 trmH; tRNA (guanosine-2'-O-)-methyltransferase [EC:2.1.1.34] D 2.1.1.35 tRNA (uracil54-C5)-methyltransferase E CH54_2714 trmA; tRNA (uracil(54)-C(5))-methyltransferase K00557 trmA; tRNA (uracil-5-)-methyltransferase [EC:2.1.1.35] D 2.1.1.37 DNA (cytosine-5-)-methyltransferase E CH54_3053 dcm; DNA (cytosine-5-)-methyltransferase family protein K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] D 2.1.1.38 O-demethylpuromycin O-methyltransferase D 2.1.1.39 inositol 3-methyltransferase D 2.1.1.40 inositol 1-methyltransferase D 2.1.1.41 sterol 24-C-methyltransferase D 2.1.1.42 flavone 3'-O-methyltransferase D 2.1.1.44 L-histidine Nalpha-methyltransferase D 2.1.1.45 thymidylate synthase E CH54_3487 thyA; thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45] D 2.1.1.46 isoflavone 4'-O-methyltransferase D 2.1.1.47 indolepyruvate C-methyltransferase D 2.1.1.49 amine N-methyltransferase D 2.1.1.50 loganate O-methyltransferase D 2.1.1.53 putrescine N-methyltransferase D 2.1.1.54 deoxycytidylate C-methyltransferase D 2.1.1.55 tRNA (adenine-N6-)-methyltransferase D 2.1.1.56 mRNA (guanine-N7)-methyltransferase D 2.1.1.57 methyltransferase cap1 D 2.1.1.59 [cytochrome c]-lysine N-methyltransferase D 2.1.1.60 calmodulin-lysine N-methyltransferase D 2.1.1.61 tRNA 5-(aminomethyl)-2-thiouridylate-methyltransferase E CH54_3868 mnmC; tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC K15461 mnmC; tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein [EC:2.1.1.61 1.5.-.-] D 2.1.1.62 mRNA (2'-O-methyladenosine-N6-)-methyltransferase D 2.1.1.63 methylated-DNA---[protein]-cysteine S-methyltransferase E CH54_381 methylated-DNA--[]-cysteine S-methyltransferase family protein K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] E CH54_2666 methylated-DNA--[]-cysteine S-methyltransferase family protein K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63] D 2.1.1.64 3-demethylubiquinol 3-O-methyltransferase E CH54_3964 ubiG; 3-demethylubiquinone-9 3-O-methyltransferase K00568 ubiG; 2-polyprenyl-6-hydroxyphenyl methylase / 3-demethylubiquinone-9 3-methyltransferase [EC:2.1.1.222 2.1.1.64] D 2.1.1.65 licodione 2'-O-methyltransferase D 2.1.1.67 thiopurine S-methyltransferase D 2.1.1.68 caffeate O-methyltransferase D 2.1.1.69 5-hydroxyfuranocoumarin 5-O-methyltransferase D 2.1.1.70 8-hydroxyfuranocoumarin 8-O-methyltransferase D 2.1.1.71 phosphatidyl-N-methylethanolamine N-methyltransferase D 2.1.1.72 site-specific DNA-methyltransferase (adenine-specific) E CH54_1925 N-6 DNA Methylase family protein K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72] E CH54_2303 dam; DNA adenine methylase family protein K06223 dam; DNA adenine methylase [EC:2.1.1.72] E CH54_2629 dam; DNA adenine methylase family protein K06223 dam; DNA adenine methylase [EC:2.1.1.72] E CH54_1523 DNA methylase family protein K07316 mod; adenine-specific DNA-methyltransferase [EC:2.1.1.72] D 2.1.1.74 methylenetetrahydrofolate---tRNA-(uracil54-C5)-methyltransferase [NAD(P)H-oxidizing] D 2.1.1.75 apigenin 4'-O-methyltransferase D 2.1.1.76 quercetin 3-O-methyltransferase D 2.1.1.77 protein-L-isoaspartate(D-aspartate) O-methyltransferase E CH54_1682 pcm; protein-L-isoaspartate O-methyltransferase K00573 E2.1.1.77; protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77] D 2.1.1.78 isoorientin 3'-O-methyltransferase D 2.1.1.79 cyclopropane-fatty-acyl-phospholipid synthase E CH54_297 L-isoaspartate family protein K00574 cfa; cyclopropane-fatty-acyl-phospholipid synthase [EC:2.1.1.79] D 2.1.1.80 protein-glutamate O-methyltransferase E CH54_808 methyltransferase domain protein K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80] D 2.1.1.82 3-methylquercetin 7-O-methyltransferase D 2.1.1.83 3,7-dimethylquercetin 4'-O-methyltransferase D 2.1.1.84 methylquercetagetin 6-O-methyltransferase D 2.1.1.85 protein-histidine N-methyltransferase D 2.1.1.86 tetrahydromethanopterin S-methyltransferase D 2.1.1.87 pyridine N-methyltransferase D 2.1.1.88 8-hydroxyquercetin 8-O-methyltransferase D 2.1.1.89 tetrahydrocolumbamine 2-O-methyltransferase D 2.1.1.90 methanol---corrinoid protein Co-methyltransferase D 2.1.1.91 isobutyraldoxime O-methyltransferase D 2.1.1.94 tabersonine 16-O-methyltransferase D 2.1.1.95 tocopherol C-methyltransferase D 2.1.1.96 thioether S-methyltransferase D 2.1.1.97 3-hydroxyanthranilate 4-C-methyltransferase D 2.1.1.98 diphthine synthase D 2.1.1.99 3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase D 2.1.1.100 protein-S-isoprenylcysteine O-methyltransferase D 2.1.1.101 macrocin O-methyltransferase D 2.1.1.102 demethylmacrocin O-methyltransferase D 2.1.1.103 phosphoethanolamine N-methyltransferase D 2.1.1.104 caffeoyl-CoA O-methyltransferase D 2.1.1.105 N-benzoyl-4-hydroxyanthranilate 4-O-methyltransferase D 2.1.1.106 tryptophan 2-C-methyltransferase D 2.1.1.107 uroporphyrinogen-III C-methyltransferase E CH54_1695 cobA; uroporphyrinogen-III C-methyltransferase K02302 cysG; uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4] E CH54_2299 cobA; uroporphyrinogen-III C-methyltransferase K02302 cysG; uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4] E CH54_961 cobA; uroporphyrinogen-III C-methyltransferase K02303 cobA; uroporphyrin-III C-methyltransferase [EC:2.1.1.107] E CH54_2770 hemX family protein K02496 hemX; uroporphyrin-III C-methyltransferase [EC:2.1.1.107] D 2.1.1.108 6-hydroxymellein O-methyltransferase D 2.1.1.109 demethylsterigmatocystin 6-O-methyltransferase D 2.1.1.110 sterigmatocystin 8-O-methyltransferase D 2.1.1.111 anthranilate N-methyltransferase D 2.1.1.112 glucuronoxylan 4-O-methyltransferase D 2.1.1.113 site-specific DNA-methyltransferase (cytosine-N4-specific) D 2.1.1.114 polyprenyldihydroxybenzoate methyltransferase D 2.1.1.115 (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase D 2.1.1.116 3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase D 2.1.1.117 (S)-scoulerine 9-O-methyltransferase D 2.1.1.118 columbamine O-methyltransferase D 2.1.1.119 10-hydroxydihydrosanguinarine 10-O-methyltransferase D 2.1.1.120 12-hydroxydihydrochelirubine 12-O-methyltransferase D 2.1.1.121 6-O-methylnorlaudanosoline 5'-O-methyltransferase D 2.1.1.122 (S)-tetrahydroprotoberberine N-methyltransferase D 2.1.1.123 [cytochrome-c]-methionine S-methyltransferase D 2.1.1.127 [ribulose-bisphosphate carboxylase]-lysine N-methyltransferase D 2.1.1.128 (RS)-norcoclaurine 6-O-methyltransferase D 2.1.1.129 inositol 4-methyltransferase D 2.1.1.130 precorrin-2 C20-methyltransferase E CH54_926 cobI; precorrin-2 C(20)-methyltransferase K03394 cobI-cbiL; precorrin-2/cobalt-factor-2 C20-methyltransferase [EC:2.1.1.130 2.1.1.151] D 2.1.1.131 precorrin-3B C17-methyltransferase E CH54_929 cobJ; precorrin-3B C17-methyltransferase K05934 cobJ; precorrin-3B C17-methyltransferase / cobalt-factor III methyltransferase [EC:2.1.1.131 2.1.1.272] D 2.1.1.132 precorrin-6B C5,15-methyltransferase (decarboxylating) D 2.1.1.133 precorrin-4 C11-methyltransferase E CH54_931 cobM; precorrin-4 C11-methyltransferase K05936 cobM; precorrin-4/cobalt-precorrin-4 C11-methyltransferase [EC:2.1.1.133 2.1.1.271] D 2.1.1.136 chlorophenol O-methyltransferase D 2.1.1.137 arsenite methyltransferase D 2.1.1.139 3'-demethylstaurosporine O-methyltransferase D 2.1.1.140 (S)-coclaurine-N-methyltransferase D 2.1.1.141 jasmonate O-methyltransferase D 2.1.1.142 cycloartenol 24-C-methyltransferase D 2.1.1.143 24-methylenesterol C-methyltransferase D 2.1.1.144 trans-aconitate 2-methyltransferase E CH54_1050 methyltransferase domain protein K00598 tam; trans-aconitate 2-methyltransferase [EC:2.1.1.144] D 2.1.1.145 trans-aconitate 3-methyltransferase D 2.1.1.146 (iso)eugenol O-methyltransferase D 2.1.1.147 corydaline synthase D 2.1.1.148 thymidylate synthase (FAD) D 2.1.1.150 isoflavone 7-O-methyltransferase D 2.1.1.151 cobalt-factor II C20-methyltransferase E CH54_926 cobI; precorrin-2 C(20)-methyltransferase K03394 cobI-cbiL; precorrin-2/cobalt-factor-2 C20-methyltransferase [EC:2.1.1.130 2.1.1.151] D 2.1.1.152 precorrin-6A synthase (deacetylating) D 2.1.1.153 vitexin 2''-O-rhamnoside 7-O-methyltransferase D 2.1.1.154 isoliquiritigenin 2'-O-methyltransferase D 2.1.1.155 kaempferol 4'-O-methyltransferase D 2.1.1.156 glycine/sarcosine N-methyltransferase D 2.1.1.157 sarcosine/dimethylglycine N-methyltransferase D 2.1.1.158 7-methylxanthosine synthase D 2.1.1.159 theobromine synthase D 2.1.1.160 caffeine synthase D 2.1.1.161 dimethylglycine N-methyltransferase D 2.1.1.162 glycine/sarcosine/dimethylglycine N-methyltransferase D 2.1.1.163 demethylmenaquinone methyltransferase E CH54_2840 ubiquinone/menaquinone biosynthesis methyltransferase family protein K03183 ubiE; demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase [EC:2.1.1.163 2.1.1.201] D 2.1.1.164 demethylrebeccamycin-D-glucose O-methyltransferase D 2.1.1.165 methyl halide transferase D 2.1.1.166 23S rRNA (uridine2552-2'-O)-methyltransferase E CH54_1987 rrmJ; ribosomal RNA large subunit methyltransferase J K02427 rlmE; 23S rRNA (uridine2552-2'-O)-methyltransferase [EC:2.1.1.166] D 2.1.1.167 27S pre-rRNA (guanosine2922-2'-O)-methyltransferase D 2.1.1.168 21S rRNA (uridine2791-2'-O)-methyltransferase D 2.1.1.169 tricetin 3',4',5'-O-trimethyltransferase D 2.1.1.170 16S rRNA (guanine527-N7)-methyltransferase E CH54_2534 rsmG; 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170] D 2.1.1.171 16S rRNA (guanine966-N2)-methyltransferase E CH54_2807 rsmD; 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD K08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171] D 2.1.1.172 16S rRNA (guanine1207-N2)-methyltransferase E CH54_1877 methyltransferase small domain protein K00564 rsmC; 16S rRNA (guanine1207-N2)-methyltransferase [EC:2.1.1.172] D 2.1.1.173 23S rRNA (guanine2445-N2)-methyltransferase D 2.1.1.174 23S rRNA (guanine1835-N2)-methyltransferase E CH54_3087 methyltransferase small domain protein K11391 rlmG; 23S rRNA (guanine1835-N2)-methyltransferase [EC:2.1.1.174] D 2.1.1.175 tricin synthase D 2.1.1.176 16S rRNA (cytosine967-C5)-methyltransferase E CH54_2221 rsmB; 16S rRNA (cytosine(967)-C(5))-methyltransferase K03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176] D 2.1.1.177 23S rRNA (pseudouridine1915-N3)-methyltransferase E CH54_1213 rlmH; rRNA large subunit m3Psi methyltransferase RlmH K00783 rlmH; 23S rRNA (pseudouridine1915-N3)-methyltransferase [EC:2.1.1.177] D 2.1.1.178 16S rRNA (cytosine1407-C5)-methyltransferase D 2.1.1.179 16S rRNA (guanine1405-N7)-methyltransferase D 2.1.1.180 16S rRNA (adenine1408-N1)-methyltransferase D 2.1.1.181 23S rRNA (adenine1618-N6)-methyltransferase E CH54_1056 hypothetical protein K06970 rlmF; 23S rRNA (adenine1618-N6)-methyltransferase [EC:2.1.1.181] D 2.1.1.182 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase E CH54_1817 rsmA; ribosomal RNA small subunit methyltransferase A K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182] D 2.1.1.183 18S rRNA (adenine1779-N6/adenine1780-N6)-dimethyltransferase D 2.1.1.184 23S rRNA (adenine2085-N6)-dimethyltransferase D 2.1.1.185 23S rRNA (guanosine2251-2'-O)-methyltransferase E CH54_2030 RNA 2'-O ribose methyltransferase substrate binding family protein K03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185] D 2.1.1.186 23S rRNA (cytidine2498-2'-O)-methyltransferase E CH54_3508 ftsJ-like methyltransferase family protein K06968 rlmM; 23S rRNA (cytidine2498-2'-O)-methyltransferase [EC:2.1.1.186] D 2.1.1.187 23S rRNA (guanine745-N1)-methyltransferase E CH54_155 ubiE/COQ5 methyltransferase family protein K00563 rlmA1; 23S rRNA (guanine745-N1)-methyltransferase [EC:2.1.1.187] D 2.1.1.188 23S rRNA (guanine748-N1)-methyltransferase D 2.1.1.189 23S rRNA (uracil747-C5)-methyltransferase E CH54_4051 rumA; 23S rRNA (uracil-5-)-methyltransferase RumA K03212 rumB; 23S rRNA (uracil747-C5)-methyltransferase [EC:2.1.1.189] D 2.1.1.190 23S rRNA (uracil1939-C5)-methyltransferase D 2.1.1.191 23S rRNA (cytosine1962-C5)-methyltransferase E CH54_23 met-10+ like-family protein K06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191] D 2.1.1.192 23S rRNA (adenine2503-C2)-methyltransferase E CH54_1452 rlmN; 23S rRNA (adenine(2503)-C(2))-methyltransferase K06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192] D 2.1.1.193 16S rRNA (uracil1498-N3)-methyltransferase E CH54_3378 RNA methyltransferase, RsmE family protein K09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193] D 2.1.1.195 cobalt-precorrin-5B (C1)-methyltransferase E CH54_934 cbiD; cobalamin biosynthesis protein CbiD K02188 cbiD; cobalt-precorrin-5B (C1)-methyltransferase [EC:2.1.1.195] D 2.1.1.196 cobalt-precorrin-6B (C15)-methyltransferase [decarboxylating] E CH54_932 cbiT; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit K02191 cbiT; cobalt-precorrin-6B (C15)-methyltransferase [EC:2.1.1.196] D 2.1.1.197 malonyl-[acyl-carrier protein] O-methyltransferase E CH54_1105 bioC; malonyl-acyl carrier protein O-methyltransferase BioC K02169 bioC; malonyl-CoA O-methyltransferase [EC:2.1.1.197] D 2.1.1.198 16S rRNA (cytidine1402-2'-O)-methyltransferase E CH54_3044 rsmI; 16S rRNA (cytidine(1402)-2'-O)-methyltransferase K07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198] D 2.1.1.199 16S rRNA (cytosine1402-N4)-methyltransferase E CH54_1787 rsmH; 16S rRNA (cytosine(1402)-N(4))-methyltransferase K03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199] D 2.1.1.200 tRNA (cytidine32/uridine32-2'-O)-methyltransferase E CH54_1469 RNA methyltransferase, TrmH, group 1 family protein K15396 trmJ; tRNA (cytidine32/uridine32-2'-O)-methyltransferase [EC:2.1.1.200] D 2.1.1.201 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase E CH54_2840 ubiquinone/menaquinone biosynthesis methyltransferase family protein K03183 ubiE; demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase [EC:2.1.1.163 2.1.1.201] D 2.1.1.202 multisite-specific tRNA:(cytosine-C5)-methyltransferase D 2.1.1.203 tRNA (cytosine34-C5)-methyltransferase D 2.1.1.204 tRNA (cytosine38-C5)-methyltransferase D 2.1.1.205 tRNA (cytidine32/guanosine34-2'-O)-methyltransferase D 2.1.1.206 tRNA (cytidine56-2'-O)-methyltransferase D 2.1.1.207 tRNA (cytidine34-2'-O)-methyltransferase E CH54_2665 trmL; tRNA (cytidine(34)-2'-O)-methyltransferase K03216 trmL; tRNA (cytidine/uridine-2'-O-)-methyltransferase [EC:2.1.1.207] D 2.1.1.208 23S rRNA (uridine2479-2'-O)-methyltransferase D 2.1.1.209 23S rRNA (guanine2535-N1)-methyltransferase D 2.1.1.210 demethylspheroidene O-methyltransferase D 2.1.1.211 tRNASer (uridine44-2'-O)-methyltransferase D 2.1.1.212 2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase D 2.1.1.213 tRNA (guanine10-N2)-dimethyltransferase D 2.1.1.214 tRNA (guanine10-N2)-methyltransferase D 2.1.1.215 tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase D 2.1.1.216 tRNA (guanine26-N2)-dimethyltransferase D 2.1.1.217 tRNA (adenine22-N1)-methyltransferase D 2.1.1.218 tRNA (adenine9-N1)-methyltransferase D 2.1.1.219 tRNA (adenine57-N1/adenine58-N1)-methyltransferase D 2.1.1.220 tRNA (adenine58-N1)-methyltransferase D 2.1.1.221 tRNA (guanine9-N1)-methyltransferase D 2.1.1.222 2-polyprenyl-6-hydroxyphenol methylase E CH54_3964 ubiG; 3-demethylubiquinone-9 3-O-methyltransferase K00568 ubiG; 2-polyprenyl-6-hydroxyphenyl methylase / 3-demethylubiquinone-9 3-methyltransferase [EC:2.1.1.222 2.1.1.64] D 2.1.1.223 tRNA1Val (adenine37-N6)-methyltransferase E CH54_1508 methyltransferase small domain protein K15460 yfiC; tRNA1Val (adenine37-N6)-methyltransferase [EC:2.1.1.223] D 2.1.1.224 23S rRNA (adenine2503-C8)-methyltransferase D 2.1.1.225 tRNA:m4X modification enzyme D 2.1.1.226 23S rRNA (cytidine1920-2'-O)-methyltransferase D 2.1.1.227 16S rRNA (cytidine1409-2'-O)-methyltransferase D 2.1.1.228 tRNA (guanine37-N1)-methyltransferase E CH54_1612 trmD; tRNA (guanine(37)-N(1))-methyltransferase K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228] D 2.1.1.229 tRNA (carboxymethyluridine34-5-O)-methyltransferase D 2.1.1.230 23S rRNA (adenosine1067-2'-O)-methyltransferase D 2.1.1.231 flavonoid 4'-O-methyltransferase D 2.1.1.232 naringenin 7-O-methyltransferase D 2.1.1.233 [phosphatase 2A protein]-leucine-carboxy methyltransferase D 2.1.1.234 dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose N,N-dimethyltransferase D 2.1.1.235 dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase D 2.1.1.236 dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose N,N-dimethyltransferase D 2.1.1.237 mycinamicin III 3''-O-methyltransferase D 2.1.1.238 mycinamicin VI 2''-O-methyltransferase D 2.1.1.239 L-olivosyl-oleandolide 3-O-methyltransferase D 2.1.1.240 trans-resveratrol di-O-methyltransferase D 2.1.1.241 2,4,7-trihydroxy-1,4-benzoxazin-3-one-glucoside 7-O-methyltransferase D 2.1.1.242 16S rRNA (guanine1516-N2)-methyltransferase E CH54_2389 SAM-dependent methyltransferase family protein K15984 rsmJ; 16S rRNA (guanine1516-N2)-methyltransferase [EC:2.1.1.242] D 2.1.1.243 2-ketoarginine methyltransferase D 2.1.1.244 protein N-terminal methyltransferase D 2.1.1.245 5-methyltetrahydrosarcinapterin---corrinoid/iron-sulfur protein Co-methyltransferase D 2.1.1.246 [methyl-Co(III) methanol-specific corrinoid protein]---coenzyme M methyltransferase D 2.1.1.247 [methyl-Co(III) methylamine-specific corrinoid protein]---coenzyme M methyltransferase D 2.1.1.248 methylamine---corrinoid protein Co-methyltransferase D 2.1.1.249 dimethylamine---corrinoid protein Co-methyltransferase D 2.1.1.250 trimethylamine---corrinoid protein Co-methyltransferase D 2.1.1.251 methylated-thiol---coenzyme M methyltransferase D 2.1.1.252 tetramethylammonium---corrinoid protein Co-methyltransferase D 2.1.1.253 [methyl-Co(III) tetramethylammonium-specific corrinoid protein]---coenzyme M methyltransferase D 2.1.1.254 erythromycin 3''-O-methyltransferase D 2.1.1.255 geranyl diphosphate 2-C-methyltransferase D 2.1.1.256 tRNA (guanine6-N2)-methyltransferase D 2.1.1.257 tRNA (pseudouridine54-N1)-methyltransferase D 2.1.1.258 5-methyltetrahydrofolate---corrinoid/iron-sulfur protein Co-methyltransferase D 2.1.1.259 [fructose-bisphosphate aldolase]-lysine N-methyltransferase D 2.1.1.260 rRNA small subunit pseudouridine methyltransferase Nep1 D 2.1.1.261 4-dimethylallyltryptophan N-methyltransferase D 2.1.1.262 squalene methyltransferase D 2.1.1.263 botryococcene C-methyltransferase D 2.1.1.264 23S rRNA (guanine2069-N7)-methyltransferase D 2.1.1.265 tellurite methyltransferase E CH54_701 tehB; tellurite resistance protein TehB K16868 tehB; tellurite methyltransferase [EC:2.1.1.265] D 2.1.1.266 23S rRNA (adenine2030-N6)-methyltransferase E CH54_2391 hypothetical protein K07115 rlmJ; 23S rRNA (adenine2030-N6)-methyltransferase [EC:2.1.1.266] D 2.1.1.267 flavonoid 3',5'-methyltransferase D 2.1.1.268 tRNAThr (cytosine32-N3)-methyltransferase D 2.1.1.269 dimethylsulfoniopropionate demethylase D 2.1.1.270 (+)-6a-hydroxymaackiain 3-O-methyltransferase D 2.1.1.271 cobalt-precorrin-4 methyltransferase E CH54_931 cobM; precorrin-4 C11-methyltransferase K05936 cobM; precorrin-4/cobalt-precorrin-4 C11-methyltransferase [EC:2.1.1.133 2.1.1.271] D 2.1.1.272 cobalt-factor III methyltransferase E CH54_929 cobJ; precorrin-3B C17-methyltransferase K05934 cobJ; precorrin-3B C17-methyltransferase / cobalt-factor III methyltransferase [EC:2.1.1.131 2.1.1.272] D 2.1.1.273 benzoate O-methyltransferase D 2.1.1.274 salicylate 1-O-methyltransferase D 2.1.1.275 gibberellin A9 O-methyltransferase D 2.1.1.276 gibberellin A4 carboxyl methyltransferase D 2.1.1.277 anthranilate O-methyltransferase D 2.1.1.278 indole-3-acetate O-methyltransferase D 2.1.1.279 trans-anol O-methyltransferase D 2.1.1.280 selenocysteine Se-methyltransferase D 2.1.1.281 phenylpyruvate C3-methyltransferase D 2.1.1.282 tRNAPhe 7-[(3-amino-3-carboxypropyl)-4-demethylwyosine37-N4]-methyltransferase D 2.1.1.283 emodin O-methyltransferase D 2.1.1.284 8-demethylnovobiocic acid C8-methyltransferase D 2.1.1.285 demethyldecarbamoylnovobiocin O-methyltransferase D 2.1.1.286 25S rRNA (adenine2142-N1)-methyltransferase D 2.1.1.287 25S rRNA (adenine645-N1)-methyltransferase D 2.1.1.288 aklanonic acid methyltransferase D 2.1.1.289 cobalt-precorrin-7 (C5)-methyltransferase E CH54_933 cbiE; precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit K03399 cbiE; cobalt-precorrin-7 (C5)-methyltransferase [EC:2.1.1.289] D 2.1.1.290 tRNAPhe [7-(3-amino-3-carboxypropyl)wyosine37-O]-methyltransferase D 2.1.1.291 (R,S)-reticuline 7-O-methyltransferase D 2.1.1.292 carminomycin 4-O-methyltransferase D 2.1.1.293 6-hydroxytryprostatin B O-methyltransferase D 2.1.1.294 3-O-phospho-polymannosyl GlcNAc-diphospho-ditrans,octacis-undecaprenol 3-phospho-methyltransferase D 2.1.1.295 2-methyl-6-phytyl-1,4-hydroquinone methyltransferase D 2.1.1.296 methyltransferase cap2 D 2.1.1.297 peptide chain release factor N5-glutamine methyltransferase E CH54_654 prmC; protein-(glutamine-N5) methyltransferase, release factor-specific K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297] D 2.1.1.298 ribosomal protein uL3 N5-glutamine methyltransferase E CH54_3862 prmB; (glutamine-N5) methyltransferase, ribosomal protein L3-specific K07320 prmB; ribosomal protein L3 glutamine methyltransferase [EC:2.1.1.298] D 2.1.1.299 protein N-terminal monomethyltransferase D 2.1.1.300 pavine N-methyltransferase D 2.1.1.301 cypemycin N-terminal methyltransferase D 2.1.1.302 3-hydroxy-5-methyl-1-naphthoate 3-O-methyltransferase D 2.1.1.303 2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase D 2.1.1.304 L-tyrosine C3-methyltransferase D 2.1.1.305 8-demethyl-8-alpha-L-rhamnosyltetracenomycin-C 2'-O-methyltransferase D 2.1.1.306 8-demethyl-8-(2-methoxy-alpha-L-rhamnosyl)tetracenomycin-C 3'-O-methyltransferase D 2.1.1.307 8-demethyl-8-(2,3-dimethoxy-alpha-L-rhamnosyl)tetracenomycin-C 4'-O-methyltransferase D 2.1.1.308 cytidylyl-2-hydroxyethylphosphonate methyltransferase D 2.1.1.309 18S rRNA (guanine1575-N7)-methyltransferase D 2.1.1.310 25S rRNA (cytosine2870-C5)-methyltransferase D 2.1.1.311 25S rRNA (cytosine2278-C5)-methyltransferase D 2.1.1.312 25S rRNA (uracil2843-N3)-methyltransferase D 2.1.1.313 25S rRNA (uracil2634-N3)-methyltransferase D 2.1.1.314 diphthine methyl ester synthase D 2.1.1.315 27-O-demethylrifamycin SV methyltransferase D 2.1.1.316 mitomycin 6-O-methyltransferase D 2.1.1.317 sphingolipid C9-methyltransferase D 2.1.1.318 [trehalose-6-phosphate synthase]-L-cysteine S-methyltransferase D 2.1.1.319 type I protein arginine methyltransferase D 2.1.1.320 type II protein arginine methyltransferase D 2.1.1.321 type III protein arginine methyltransferase D 2.1.1.322 type IV protein arginine methyltransferase D 2.1.1.323 (-)-pluviatolide 4-O-methyltransferase D 2.1.1.324 dTDP-4-amino-2,3,4,6-tetradeoxy-D-glucose N,N-dimethyltransferase D 2.1.1.325 juvenile hormone-III synthase D 2.1.1.326 N-acetyldemethylphosphinothricin P-methyltransferase D 2.1.1.327 phenazine-1-carboxylate N-methyltransferase D 2.1.1.328 N-demethylindolmycin N-methyltransferase D 2.1.1.329 demethylphylloquinol methyltransferase D 2.1.1.330 5'-demethylyatein 5'-O-methyltransferase D 2.1.1.331 bacteriochlorophyllide d C-121-methyltransferase D 2.1.1.332 bacteriochlorophyllide d C-82-methyltransferase D 2.1.1.333 bacteriochlorophyllide d C-20 methyltransferase D 2.1.1.334 methanethiol S-methyltransferase D 2.1.1.335 4-amino-anhydrotetracycline N4-methyltransferase D 2.1.1.336 norbelladine O-methyltransferase D 2.1.1.337 reticuline N-methyltransferase D 2.1.1.338 desmethylxanthohumol 6'-O-methyltransferase D 2.1.1.339 xanthohumol 4-O-methyltransferase D 2.1.1.340 3-aminomethylindole N-methyltransferase D 2.1.1.341 vanillate/3-O-methylgallate O-demethylase D 2.1.1.342 anaerobilin synthase D 2.1.1.343 8-amino-8-demethylriboflavin N,N-dimethyltransferase D 2.1.1.344 ornithine lipid N-methyltransferase D 2.1.1.345 psilocybin synthase D 2.1.1.346 U6 snRNA m6A methyltransferase D 2.1.1.347 (+)-O-methylkolavelool synthase D 2.1.1.348 mRNA m6A methyltransferase D 2.1.1.349 toxoflavin synthase D 2.1.1.350 menaquinone C8-methyltransferase D 2.1.1.351 nocamycin O-methyltransferase D 2.1.1.352 3-O-acetyl-4'-O-demethylpapaveroxine 4'-O-methyltransferase D 2.1.1.353 demethylluteothin O-methyltransferase D 2.1.1.354 [histone H3]-lysine4 N-trimethyltransferase D 2.1.1.355 [histone H3]-lysine9 N-trimethyltransferase D 2.1.1.356 [histone H3]-lysine27 N-trimethyltransferase D 2.1.1.357 [histone H3]-lysine36 N-dimethyltransferase D 2.1.1.359 [histone H3]-lysine36 N-trimethyltransferase D 2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase D 2.1.1.361 [histone H4]-lysine20 N-methyltransferase D 2.1.1.362 [histone H4]-N-methyl-L-lysine20 N-methyltransferase D 2.1.1.363 pre-sodorifen synthase D 2.1.1.364 [histone H3]-lysine4 N-methyltransferase D 2.1.1.365 MMP 1-O-methyltransferase D 2.1.1.366 [histone H3]-N6,N6-dimethyl-lysine9 N-methyltransferase D 2.1.1.367 [histone H3]-lysine9 N-methyltransferase D 2.1.1.368 [histone H3]-lysine9 N-dimethyltransferase D 2.1.1.369 [histone H3]-lysine27 N-methyltransferase D 2.1.1.370 [histone H3]-lysine4 N-dimethyltransferase D 2.1.1.371 [histone H3]-lysine27 N-dimethyltransferase D 2.1.1.372 [histone H4]-lysine20 N-trimethyltransferase D 2.1.1.373 2-hydroxy-4-(methylsulfanyl)butanoate S-methyltransferase D 2.1.1.374 2-heptyl-1-hydroxyquinolin-4(1H)-one methyltransferase D 2.1.1.375 NNS virus cap methyltransferase D 2.1.1.376 glycine betaine---corrinoid protein Co-methyltransferase D 2.1.1.377 [methyl-Co(III) glycine betaine-specific corrinoid protein]---coenzyme M methyltransferase D 2.1.1.378 [methyl-Co(III) glycine betaine-specific corrinoid protein]---tetrahydrofolate methyltransferase D 2.1.1.379 [methyl coenzyme M reductase]-L-arginine C-5-methyltransferase D 2.1.1.380 3-amino-4-hydroxybenzoate 4-O-methyltransferase D 2.1.1.381 arginine Nomega-methyltransferase D 2.1.1.382 methoxylated aromatic compound---corrinoid protein Co-methyltransferase D 2.1.1.383 L-carnitine---corrinoid protein Co-methyltransferase D 2.1.1.384 [methyl-Co(III) methoxylated-aromatic-compound-specific corrinoid protein]---tetrahydromethanopterin methyltransferase D 2.1.1.385 [methyl-Co(III) methoxylated-aromatic-compound-specific corrinoid protein]---tetrahydrofolate methyltransferase D 2.1.1.386 small RNA 2'-O-methyltransferase D 2.1.1.387 5-dehydro-6-demethoxy-6-hydroxyfumagillol O-methyltransferase D 2.1.1.388 proline betaine---corrinoid protein Co-methyltransferase D 2.1.1.389 [methyl-Co(III) quaternary-amine-specific corrinoid protein]---tetrahydrofolate methyltransferase D 2.1.1.390 gentamicin X2 methyltransferase D 2.1.1.391 demethylgadusol O-methyltransferase C 2.1.2 Hydroxymethyl-, formyl- and related transferases D 2.1.2.1 glycine hydroxymethyltransferase E CH54_1475 beta-eliminating lyase family protein K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1] D 2.1.2.2 phosphoribosylglycinamide formyltransferase 1 E CH54_1355 purN; phosphoribosylglycinamide formyltransferase K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2] D 2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase E CH54_2896 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] D 2.1.2.4 glycine formimidoyltransferase D 2.1.2.5 glutamate formimidoyltransferase D 2.1.2.7 D-alanine 2-hydroxymethyltransferase D 2.1.2.8 deoxycytidylate 5-hydroxymethyltransferase D 2.1.2.9 methionyl-tRNA formyltransferase E CH54_2220 fmt; methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9] D 2.1.2.10 aminomethyltransferase E CH54_3406 gcvT; glycine cleavage system T protein K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10] D 2.1.2.11 3-methyl-2-oxobutanoate hydroxymethyltransferase E CH54_1732 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase K00606 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase [EC:2.1.2.11] D 2.1.2.13 UDP-4-amino-4-deoxy-L-arabinose formyltransferase E CH54_266 3-beta hydroxysteroid dehydrogenase/isomerase family protein K10011 arnA; UDP-4-amino-4-deoxy-L-arabinose formyltransferase / UDP-glucuronic acid dehydrogenase (UDP-4-keto-hexauronic acid decarboxylating) [EC:2.1.2.13 1.1.1.305] D 2.1.2.14 GDP-perosamine N-formyltransferase C 2.1.3 Carboxy- and carbamoyltransferases D 2.1.3.1 methylmalonyl-CoA carboxytransferase D 2.1.3.2 aspartate carbamoyltransferase E CH54_3005 pyrB; aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2] D 2.1.3.3 ornithine carbamoyltransferase E CH54_1936 argF; ornithine carbamoyltransferase K00611 OTC; ornithine carbamoyltransferase [EC:2.1.3.3] D 2.1.3.5 oxamate carbamoyltransferase D 2.1.3.6 putrescine carbamoyltransferase D 2.1.3.7 3-hydroxymethylcephem carbamoyltransferase D 2.1.3.8 lysine carbamoyltransferase D 2.1.3.9 N-acetylornithine carbamoyltransferase D 2.1.3.10 malonyl-S-ACP:biotin-protein carboxyltransferase D 2.1.3.11 N-succinylornithine carbamoyltransferase D 2.1.3.12 decarbamoylnovobiocin carbamoyltransferase D 2.1.3.15 acetyl-CoA carboxytransferase E CH54_3536 accA; acetyl-CoA carboxylase, carboxyl transferase, alpha subunit K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15] E CH54_3893 accD; acetyl-CoA carboxylase, carboxyl transferase, beta subunit K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15] D 2.1.3.16 ureidoglycine carbamoyltransferase C 2.1.4 Amidinotransferases D 2.1.4.1 glycine amidinotransferase D 2.1.4.2 scyllo-inosamine-4-phosphate amidinotransferase D 2.1.4.3 L-arginine:L-lysine amidinotransferase C 2.1.5 Methylenetransferases D 2.1.5.1 sesamin methylene transferase B 2.2 Transferring aldehyde or ketonic groups C 2.2.1 Transketolases and transaldolases D 2.2.1.1 transketolase E CH54_3389 tkt; transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1] D 2.2.1.2 transaldolase E CH54_1844 tal; transaldolase K00616 TALDO1; transaldolase [EC:2.2.1.2] D 2.2.1.3 formaldehyde transketolase D 2.2.1.4 acetoin---ribose-5-phosphate transaldolase D 2.2.1.5 2-hydroxy-3-oxoadipate synthase D 2.2.1.6 acetolactate synthase E CH54_392 ilvB; acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] E CH54_2727 ilvB; acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] E CH54_1792 ilvB; acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6] E CH54_391 ACT domain protein K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] E CH54_1791 ilvN; acetolactate synthase, small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6] E CH54_2728 ACT domain protein K11258 ilvM; acetolactate synthase II small subunit [EC:2.2.1.6] D 2.2.1.7 1-deoxy-D-xylulose-5-phosphate synthase E CH54_3668 dxs; 1-deoxy-D-xylulose-5-phosphate synthase K01662 dxs; 1-deoxy-D-xylulose-5-phosphate synthase [EC:2.2.1.7] D 2.2.1.8 fluorothreonine transaldolase D 2.2.1.9 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase E CH54_3951 menD; 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase K02551 menD; 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [EC:2.2.1.9] D 2.2.1.10 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase D 2.2.1.11 6-deoxy-5-ketofructose 1-phosphate synthase D 2.2.1.12 3-acetyloctanal synthase D 2.2.1.13 apulose-4-phosphate transketolase D 2.2.1.14 6-deoxy-6-sulfo-D-fructose transaldolase D 2.2.1.15 6-deoxy-6-sulfo-D-fructose transketolase B 2.3 Acyltransferases C 2.3.1 Transferring groups other than aminoacyl groups D 2.3.1.1 amino-acid N-acetyltransferase E CH54_3496 argA; amino-acid N-acetyltransferase K14682 argAB; amino-acid N-acetyltransferase [EC:2.3.1.1] D 2.3.1.2 imidazole N-acetyltransferase D 2.3.1.3 glucosamine N-acetyltransferase D 2.3.1.4 glucosamine-phosphate N-acetyltransferase D 2.3.1.5 arylamine N-acetyltransferase D 2.3.1.6 choline O-acetyltransferase D 2.3.1.7 carnitine O-acetyltransferase D 2.3.1.8 phosphate acetyltransferase E CH54_3913 pta; phosphate acetyltransferase K13788 pta; phosphate acetyltransferase [EC:2.3.1.8] D 2.3.1.9 acetyl-CoA C-acetyltransferase D 2.3.1.10 hydrogen-sulfide S-acetyltransferase D 2.3.1.11 thioethanolamine S-acetyltransferase D 2.3.1.12 dihydrolipoyllysine-residue acetyltransferase E CH54_1755 aceF; dihydrolipoyllysine-residue acetyltransferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] D 2.3.1.13 glycine N-acyltransferase D 2.3.1.14 glutamine N-phenylacetyltransferase D 2.3.1.15 glycerol-3-phosphate 1-O-acyltransferase E CH54_2926 plsB; glycerol-3-phosphate O-acyltransferase K00631 plsB; glycerol-3-phosphate O-acyltransferase [EC:2.3.1.15] D 2.3.1.16 acetyl-CoA C-acyltransferase E CH54_2851 fadA; acetyl-CoA C-acyltransferase FadA K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16] E CH54_3858 fadI; acetyl-CoA C-acyltransferase FadI K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16] D 2.3.1.17 aspartate N-acetyltransferase D 2.3.1.18 galactoside O-acetyltransferase D 2.3.1.19 phosphate butyryltransferase D 2.3.1.20 diacylglycerol O-acyltransferase D 2.3.1.21 carnitine O-palmitoyltransferase D 2.3.1.22 2-acylglycerol O-acyltransferase D 2.3.1.23 1-acylglycerophosphocholine O-acyltransferase D 2.3.1.24 sphingosine N-acyltransferase D 2.3.1.25 plasmalogen synthase D 2.3.1.26 sterol O-acyltransferase D 2.3.1.27 cortisol O-acetyltransferase D 2.3.1.28 chloramphenicol O-acetyltransferase D 2.3.1.29 glycine C-acetyltransferase E CH54_2655 kbl; glycine C-acetyltransferase K00639 kbl; glycine C-acetyltransferase [EC:2.3.1.29] D 2.3.1.30 serine O-acetyltransferase E CH54_2664 cysE; serine O-acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30] D 2.3.1.31 homoserine O-acetyltransferase E CH54_2904 metA; homoserine O-succinyltransferase K00651 metA; homoserine O-succinyltransferase/O-acetyltransferase [EC:2.3.1.46 2.3.1.31] D 2.3.1.32 lysine N-acetyltransferase D 2.3.1.33 histidine N-acetyltransferase D 2.3.1.34 D-tryptophan N-acetyltransferase D 2.3.1.35 glutamate N-acetyltransferase D 2.3.1.36 D-amino-acid N-acetyltransferase D 2.3.1.37 5-aminolevulinate synthase D 2.3.1.38 [acyl-carrier-protein] S-acetyltransferase D 2.3.1.39 [acyl-carrier-protein] S-malonyltransferase E CH54_77 fabD; malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] D 2.3.1.40 acyl-[acyl-carrier-protein]---phospholipid O-acyltransferase E CH54_3479 acyltransferase family protein K05939 aas; acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase / long-chain-fatty-acid--[acyl-carrier-protein] ligase [EC:2.3.1.40 6.2.1.20] D 2.3.1.41 beta-ketoacyl-[acyl-carrier-protein] synthase I E CH54_3869 hypothetical protein K00647 fabB; 3-oxoacyl-[acyl-carrier-protein] synthase I [EC:2.3.1.41] D 2.3.1.42 glycerone-phosphate O-acyltransferase D 2.3.1.43 phosphatidylcholine---sterol O-acyltransferase D 2.3.1.44 N-acetylneuraminate 4-O-acetyltransferase D 2.3.1.45 N-acetylneuraminate 7-O(or 9-O)-acetyltransferase D 2.3.1.46 homoserine O-succinyltransferase E CH54_2904 metA; homoserine O-succinyltransferase K00651 metA; homoserine O-succinyltransferase/O-acetyltransferase [EC:2.3.1.46 2.3.1.31] D 2.3.1.47 8-amino-7-oxononanoate synthase E CH54_1106 bioF; 8-amino-7-oxononanoate synthase K00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47] D 2.3.1.48 histone acetyltransferase D 2.3.1.49 deacetyl-[citrate-(pro-3S)-lyase] S-acetyltransferase D 2.3.1.50 serine C-palmitoyltransferase D 2.3.1.51 1-acylglycerol-3-phosphate O-acyltransferase E CH54_3131 1-acylglycerol-3-phosphate O-acyltransferases domain protein K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51] D 2.3.1.52 2-acylglycerol-3-phosphate O-acyltransferase D 2.3.1.53 phenylalanine N-acetyltransferase E CH54_2362 acetyltransferase domain protein K03825 aaaT; L-phenylalanine/L-methionine N-acetyltransferase [EC:2.3.1.53 2.3.1.-] D 2.3.1.54 formate C-acetyltransferase E CH54_4087 pflB; formate acetyltransferase K00656 E2.3.1.54; formate C-acetyltransferase [EC:2.3.1.54] D 2.3.1.56 aromatic-hydroxylamine O-acetyltransferase D 2.3.1.57 diamine N-acetyltransferase E CH54_1356 acetyltransferase domain protein K00657 speG; diamine N-acetyltransferase [EC:2.3.1.57] D 2.3.1.58 2,3-diaminopropionate N-oxalyltransferase D 2.3.1.59 gentamicin 2'-N-acetyltransferase D 2.3.1.60 gentamicin 3-N-acetyltransferase D 2.3.1.61 dihydrolipoyllysine-residue succinyltransferase E CH54_1146 sucB; dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase complex K00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61] D 2.3.1.62 2-acylglycerophosphocholine O-acyltransferase D 2.3.1.63 1-alkylglycerophosphocholine O-acyltransferase D 2.3.1.64 agmatine N4-coumaroyltransferase D 2.3.1.65 bile acid-CoA:amino acid N-acyltransferase D 2.3.1.66 leucine N-acetyltransferase D 2.3.1.67 1-alkylglycerophosphocholine O-acetyltransferase D 2.3.1.68 glutamine N-acyltransferase D 2.3.1.69 monoterpenol O-acetyltransferase D 2.3.1.71 glycine N-benzoyltransferase D 2.3.1.72 indoleacetylglucose---inositol O-acyltransferase D 2.3.1.73 diacylglycerol---sterol O-acyltransferase D 2.3.1.74 chalcone synthase D 2.3.1.75 long-chain-alcohol O-fatty-acyltransferase D 2.3.1.76 retinol O-fatty-acyltransferase D 2.3.1.77 triacylglycerol---sterol O-acyltransferase D 2.3.1.78 heparan-alpha-glucosaminide N-acetyltransferase D 2.3.1.79 maltose O-acetyltransferase D 2.3.1.80 cysteine-S-conjugate N-acetyltransferase D 2.3.1.81 aminoglycoside 3-N-acetyltransferase D 2.3.1.82 aminoglycoside 6'-N-acetyltransferase D 2.3.1.83 phosphatidylcholine---dolichol O-acyltransferase D 2.3.1.84 alcohol O-acetyltransferase D 2.3.1.85 fatty-acid synthase system D 2.3.1.86 fatty-acyl-CoA synthase system D 2.3.1.87 aralkylamine N-acetyltransferase D 2.3.1.89 tetrahydrodipicolinate N-acetyltransferase D 2.3.1.90 beta-glucogallin O-galloyltransferase D 2.3.1.91 sinapoylglucose---choline O-sinapoyltransferase D 2.3.1.92 sinapoylglucose---malate O-sinapoyltransferase D 2.3.1.93 13-hydroxylupanine O-tigloyltransferase D 2.3.1.94 6-deoxyerythronolide-B synthase D 2.3.1.95 trihydroxystilbene synthase D 2.3.1.97 glycylpeptide N-tetradecanoyltransferase D 2.3.1.98 chlorogenate---glucarate O-hydroxycinnamoyltransferase D 2.3.1.99 quinate O-hydroxycinnamoyltransferase D 2.3.1.100 [myelin-proteolipid] O-palmitoyltransferase D 2.3.1.101 formylmethanofuran---tetrahydromethanopterin N-formyltransferase D 2.3.1.102 N6-hydroxylysine N-acetyltransferase D 2.3.1.103 sinapoylglucose---sinapoylglucose O-sinapoyltransferase D 2.3.1.105 alkylglycerophosphate 2-O-acetyltransferase D 2.3.1.106 tartronate O-hydroxycinnamoyltransferase D 2.3.1.107 deacetylvindoline O-acetyltransferase D 2.3.1.108 alpha-tubulin N-acetyltransferase D 2.3.1.109 arginine N-succinyltransferase E CH54_680 astA; arginine N-succinyltransferase K00673 astA; arginine N-succinyltransferase [EC:2.3.1.109] D 2.3.1.110 tyramine N-feruloyltransferase D 2.3.1.111 mycocerosate synthase D 2.3.1.112 D-tryptophan N-malonyltransferase D 2.3.1.113 anthranilate N-malonyltransferase D 2.3.1.114 3,4-dichloroaniline N-malonyltransferase D 2.3.1.115 isoflavone-7-O-beta-glucoside 6''-O-malonyltransferase D 2.3.1.116 flavonol-3-O-beta-glucoside O-malonyltransferase D 2.3.1.117 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase E CH54_3517 dapD; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase K00674 dapD; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [EC:2.3.1.117] D 2.3.1.118 N-hydroxyarylamine O-acetyltransferase D 2.3.1.121 1-alkenylglycerophosphoethanolamine O-acyltransferase D 2.3.1.122 trehalose O-mycolyltransferase D 2.3.1.123 dolichol O-acyltransferase D 2.3.1.125 1-alkyl-2-acetylglycerol O-acyltransferase D 2.3.1.126 isocitrate O-dihydroxycinnamoyltransferase D 2.3.1.127 ornithine N-benzoyltransferase D 2.3.1.129 acyl-[acyl-carrier-protein]---UDP-N-acetylglucosamine O-acyltransferase E CH54_593 lpxA; acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase K00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129] E CH54_3532 lpxA; acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase K00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129] D 2.3.1.130 galactarate O-hydroxycinnamoyltransferase D 2.3.1.131 glucarate O-hydroxycinnamoyltransferase D 2.3.1.132 glucarolactone O-hydroxycinnamoyltransferase D 2.3.1.133 shikimate O-hydroxycinnamoyltransferase D 2.3.1.134 galactolipid O-acyltransferase D 2.3.1.135 phosphatidylcholine---retinol O-acyltransferase D 2.3.1.136 polysialic-acid O-acetyltransferase D 2.3.1.137 carnitine O-octanoyltransferase D 2.3.1.138 putrescine N-hydroxycinnamoyltransferase D 2.3.1.139 ecdysone O-acyltransferase D 2.3.1.140 rosmarinate synthase D 2.3.1.141 galactosylacylglycerol O-acyltransferase D 2.3.1.142 glycoprotein O-fatty-acyltransferase D 2.3.1.143 beta-glucogallin---tetrakisgalloylglucose O-galloyltransferase D 2.3.1.144 anthranilate N-benzoyltransferase D 2.3.1.145 piperidine N-piperoyltransferase D 2.3.1.146 pinosylvin synthase D 2.3.1.147 glycerophospholipid arachidonoyl-transferase (CoA-independent) D 2.3.1.148 glycerophospholipid acyltransferase (CoA-dependent) D 2.3.1.149 platelet-activating factor acetyltransferase D 2.3.1.150 salutaridinol 7-O-acetyltransferase D 2.3.1.151 2,3',4,6-tetrahydroxybenzophenone synthase D 2.3.1.152 alcohol O-cinnamoyltransferase D 2.3.1.153 anthocyanin 5-(6'''-hydroxycinnamoyltransferase) D 2.3.1.155 acetyl-CoA C-myristoyltransferase D 2.3.1.156 phloroisovalerophenone synthase D 2.3.1.157 glucosamine-1-phosphate N-acetyltransferase E CH54_2524 glmU; UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase K04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157] D 2.3.1.158 phospholipid:diacylglycerol acyltransferase D 2.3.1.159 acridone synthase D 2.3.1.160 vinorine synthase D 2.3.1.161 lovastatin nonaketide synthase D 2.3.1.162 taxadien-5alpha-ol O-acetyltransferase D 2.3.1.163 10-hydroxytaxane O-acetyltransferase D 2.3.1.164 isopenicillin-N N-acyltransferase D 2.3.1.165 6-methylsalicylic-acid synthase D 2.3.1.166 2alpha-hydroxytaxane 2-O-benzoyltransferase D 2.3.1.167 10-deacetylbaccatin III 10-O-acetyltransferase D 2.3.1.168 dihydrolipoyllysine-residue (2-methylpropanoyl)transferase D 2.3.1.169 CO-methylating acetyl-CoA synthase D 2.3.1.170 6'-deoxychalcone synthase D 2.3.1.171 anthocyanin 6''-O-malonyltransferase D 2.3.1.172 anthocyanin 5-O-glucoside 6'''-O-malonyltransferase D 2.3.1.173 flavonol-3-O-triglucoside O-coumaroyltransferase D 2.3.1.174 3-oxoadipyl-CoA thiolase D 2.3.1.175 deacetylcephalosporin-C acetyltransferase D 2.3.1.176 propanoyl-CoA C-acyltransferase D 2.3.1.177 3,5-dihydroxybiphenyl synthase D 2.3.1.178 diaminobutyrate acetyltransferase D 2.3.1.179 beta-ketoacyl-[acyl-carrier-protein] synthase II E CH54_7 fabF; beta-ketoacyl-acyl-carrier-protein synthase II K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] E CH54_80 fabF; beta-ketoacyl-acyl-carrier-protein synthase II K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] E CH54_1661 hypothetical protein K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] D 2.3.1.180 beta-ketoacyl-[acyl-carrier-protein] synthase III E CH54_76 fabH; 3-oxoacyl-[acyl-carrier-] synthase III family protein K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180] D 2.3.1.181 lipoyl(octanoyl) transferase E CH54_1219 lipB; lipoyl(octanoyl) transferase K03801 lipB; lipoyl(octanoyl) transferase [EC:2.3.1.181] D 2.3.1.183 phosphinothricin acetyltransferase D 2.3.1.184 acyl-homoserine-lactone synthase D 2.3.1.185 tropine acyltransferase D 2.3.1.186 pseudotropine acyltransferase D 2.3.1.187 acetyl-S-ACP:malonate ACP transferase D 2.3.1.188 omega-hydroxypalmitate O-feruloyl transferase D 2.3.1.189 mycothiol synthase D 2.3.1.190 acetoin dehydrogenase system D 2.3.1.191 UDP-3-O-(3-hydroxyacyl)glucosamine N-acyltransferase E CH54_3530 lpxD; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD K02536 lpxD; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase [EC:2.3.1.191] D 2.3.1.192 glycine N-phenylacetyltransferase D 2.3.1.193 tRNAMet cytidine acetyltransferase E CH54_1340 acetyltransferase family protein K06957 tmcA; tRNA(Met) cytidine acetyltransferase [EC:2.3.1.193] D 2.3.1.194 acetoacetyl-CoA synthase D 2.3.1.195 (Z)-3-hexen-1-ol acetyltransferase D 2.3.1.196 benzyl alcohol O-benzoyltransferase D 2.3.1.197 dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N-acetyltransferase D 2.3.1.198 glycerol-3-phosphate 2-O-acyltransferase D 2.3.1.199 very-long-chain 3-oxoacyl-CoA synthase D 2.3.1.200 lipoyl amidotransferase D 2.3.1.201 UDP-2-acetamido-3-amino-2,3-dideoxy-glucuronate N-acetyltransferase D 2.3.1.202 UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase D 2.3.1.203 UDP-N-acetylbacillosamine N-acetyltransferase D 2.3.1.204 octanoyl-[GcvH]:protein N-octanoyltransferase D 2.3.1.205 fumigaclavine B O-acetyltransferase D 2.3.1.206 3,5,7-trioxododecanoyl-CoA synthase D 2.3.1.207 beta-ketodecanoyl-[acyl-carrier-protein] synthase D 2.3.1.208 4-hydroxycoumarin synthase D 2.3.1.209 dTDP-4-amino-4,6-dideoxy-D-glucose acyltransferase D 2.3.1.210 dTDP-4-amino-4,6-dideoxy-D-galactose acyltransferase E CH54_2756 wecD; TDP-D-fucosamine acetyltransferase K16704 rffC; dTDP-4-amino-4,6-dideoxy-D-galactose acyltransferase [EC:2.3.1.210] D 2.3.1.211 bisdemethoxycurcumin synthase D 2.3.1.212 benzalacetone synthase D 2.3.1.213 cyanidin 3-O-(6-O-glucosyl-2-O-xylosylgalactoside) 6'''-O-hydroxycinnamoyltransferase D 2.3.1.214 pelargonidin 3-O-(6-caffeoylglucoside) 5-O-(6-O-malonylglucoside) 4'''-malonyltransferase D 2.3.1.215 anthocyanidin 3-O-glucoside 6''-O-acyltransferase D 2.3.1.216 5,7-dihydroxy-2-methylchromone synthase D 2.3.1.217 curcumin synthase D 2.3.1.218 phenylpropanoylacetyl-CoA synthase D 2.3.1.219 demethoxycurcumin synthase D 2.3.1.220 2,4,6-trihydroxybenzophenone synthase D 2.3.1.221 noranthrone synthase D 2.3.1.222 phosphate propanoyltransferase E CH54_950 propanediol utilization PduL family protein K13923 pduL; phosphate propanoyltransferase [EC:2.3.1.222] D 2.3.1.223 3-oxo-5,6-didehydrosuberyl-CoA thiolase D 2.3.1.224 acetyl-CoA-benzylalcohol acetyltransferase D 2.3.1.225 protein S-acyltransferase D 2.3.1.226 carboxymethylproline synthase D 2.3.1.227 GDP-perosamine N-acetyltransferase D 2.3.1.228 isovaleryl-homoserine lactone synthase D 2.3.1.229 4-coumaroyl-homoserine lactone synthase D 2.3.1.230 2-heptyl-4(1H)-quinolone synthase D 2.3.1.231 tRNAPhe {7-[3-amino-3-(methoxycarbonyl)propyl]wyosine37-N}-methoxycarbonyltransferase D 2.3.1.232 methanol O-anthraniloyltransferase D 2.3.1.233 1,3,6,8-tetrahydroxynaphthalene synthase D 2.3.1.234 N6-L-threonylcarbamoyladenine synthase E CH54_3106 tsaD; tRNA threonylcarbamoyl adenosine modification protein TsaD K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234] D 2.3.1.235 tetracenomycin F2 synthase D 2.3.1.236 5-methylnaphthoic acid synthase D 2.3.1.237 neocarzinostatin naphthoate synthase D 2.3.1.238 monacolin J acid methylbutanoate transferase D 2.3.1.239 10-deoxymethynolide synthase D 2.3.1.240 narbonolide synthase D 2.3.1.241 Kdo2-lipid IVA acyltransferase E CH54_59 lpxL; lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase family protein K02517 lpxL; Kdo2-lipid IVA lauroyltransferase/acyltransferase [EC:2.3.1.241 2.3.1.-] D 2.3.1.242 Kdo2-lipid IVA palmitoleoyltransferase E CH54_2951 lpxL; lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase family protein K12974 lpxP; KDO2-lipid IV(A) palmitoleoyltransferase [EC:2.3.1.242] D 2.3.1.243 acyl-Kdo2-lipid IVA acyltransferase E CH54_615 msbB; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase K02560 lpxM; lauroyl-Kdo2-lipid IVA myristoyltransferase [EC:2.3.1.243] D 2.3.1.244 2-methylbutanoate polyketide synthase D 2.3.1.245 3-hydroxy-5-phosphooxypentane-2,4-dione thiolase E CH54_1907 deoC/LacD aldolase family protein K08321 lsrF; 3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase [EC:2.3.1.245] D 2.3.1.246 3,5-dihydroxyphenylacetyl-CoA synthase D 2.3.1.247 3-keto-5-aminohexanoate cleavage enzyme D 2.3.1.248 spermidine disinapoyl transferase D 2.3.1.249 spermidine dicoumaroyl transferase D 2.3.1.250 [Wnt protein] O-palmitoleoyl transferase D 2.3.1.251 lipid IVA palmitoyltransferase E CH54_151 antimicrobial peptide resistance and lipid A acylation PagP family protein K12973 pagP; lipid IVA palmitoyltransferase [EC:2.3.1.251] D 2.3.1.252 mycolipanoate synthase D 2.3.1.253 phloroglucinol synthase D 2.3.1.254 N-terminal methionine Nalpha-acetyltransferase NatB D 2.3.1.255 N-terminal amino-acid Nalpha-acetyltransferase NatA D 2.3.1.256 N-terminal methionine Nalpha-acetyltransferase NatC D 2.3.1.257 N-terminal L-serine Nalpha-acetyltransferase NatD D 2.3.1.258 N-terminal methionine Nalpha-acetyltransferase NatE D 2.3.1.259 N-terminal methionine Nalpha-acetyltransferase NatF D 2.3.1.260 tetracycline polyketide synthase D 2.3.1.261 (4-hydroxyphenyl)alkanoate synthase D 2.3.1.262 anthraniloyl-CoA anthraniloyltransferase D 2.3.1.263 2-amino-4-oxopentanoate thiolase D 2.3.1.264 beta-lysine N6-acetyltransferase D 2.3.1.265 phosphatidylinositol dimannoside acyltransferase D 2.3.1.266 [ribosomal protein bS18]-alanine N-acetyltransferase E CH54_1875 rimI; ribosomal-protein-alanine acetyltransferase K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266] D 2.3.1.267 [ribosomal protein uS5]-alanine N-acetyltransferase E CH54_639 acetyltransferase family protein K03790 rimJ; [ribosomal protein S5]-alanine N-acetyltransferase [EC:2.3.1.267] D 2.3.1.268 ethanol O-acetyltransferase D 2.3.1.269 apolipoprotein N-acyltransferase E CH54_1200 lnt; apolipoprotein N-acyltransferase K03820 lnt; apolipoprotein N-acyltransferase [EC:2.3.1.269] D 2.3.1.270 lyso-ornithine lipid O-acyltransferase D 2.3.1.271 L-glutamate-5-semialdehyde N-acetyltransferase D 2.3.1.272 2-acetylphloroglucinol acetyltransferase D 2.3.1.273 diglucosylglycerate octanoyltransferase D 2.3.1.274 phosphate acyltransferase E CH54_75 plsX; fatty acid/phospholipid synthesis protein PlsX K03621 plsX; phosphate acyltransferase [EC:2.3.1.274] D 2.3.1.275 acyl phosphate:glycerol-3-phosphate acyltransferase E CH54_3107 plsY; acyl-phosphate glycerol 3-phosphate acyltransferase K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275] D 2.3.1.276 galactosamine-1-phosphate N-acetyltransferase D 2.3.1.277 2-oxo-3-(phosphooxy)propyl 3-oxoalkanoate synthase D 2.3.1.278 mycolipenoyl-CoA---2-(long-chain-fatty acyl)-trehalose mycolipenoyltransferase D 2.3.1.279 long-chain-acyl-CoA---trehalose acyltransferase D 2.3.1.280 (aminoalkyl)phosphonate N-acetyltransferase D 2.3.1.281 5-hydroxydodecatetraenal polyketide synthase D 2.3.1.282 phenolphthiocerol/phthiocerol/phthiodiolone dimycocerosyl transferase D 2.3.1.283 2'-acyl-2-O-sulfo-trehalose (hydroxy)phthioceranyltransferase D 2.3.1.284 3'-(hydroxy)phthioceranyl-2'-palmitoyl(stearoyl)-2-O-sulfo-trehalose (hydroxy)phthioceranyltransferase D 2.3.1.285 (13S,14R)-1,13-dihydroxy-N-methylcanadine 13-O-acetyltransferase D 2.3.1.286 protein acetyllysine N-acetyltransferase E CH54_108 sir2 family protein K12410 cobB; NAD-dependent protein deacetylase/lipoamidase [EC:2.3.1.286 2.3.1.313] D 2.3.1.287 phthioceranic/hydroxyphthioceranic acid synthase D 2.3.1.288 2-O-sulfo trehalose long-chain-acyltransferase D 2.3.1.289 aureothin polyketide synthase system D 2.3.1.290 spectinabilin polyketide synthase system D 2.3.1.291 sphingoid base N-palmitoyltransferase D 2.3.1.292 (phenol)carboxyphthiodiolenone synthase D 2.3.1.293 meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase I D 2.3.1.294 meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase II D 2.3.1.295 mycoketide-CoA synthase D 2.3.1.296 omega-hydroxyceramide transacylase D 2.3.1.297 very-long-chain ceramide synthase D 2.3.1.298 ultra-long-chain ceramide synthase D 2.3.1.299 sphingoid base N-stearoyltransferase D 2.3.1.300 branched-chain beta-ketoacyl-[acyl-carrier-protein] synthase D 2.3.1.301 mycobacterial beta-ketoacyl-[acyl carrier protein] synthase III D 2.3.1.302 hydroxycinnamoyl-CoA:5-hydroxyanthranilate N-hydroxycinnamoyltransferase D 2.3.1.303 alpha-L-Rha-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-PP-Und 2IV-O-acetyltransferase D 2.3.1.304 poly[(R)-3-hydroxyalkanoate] polymerase D 2.3.1.305 acyl-[acyl-carrier protein]---UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucopyranose N-acyltransferase D 2.3.1.306 acetyl-CoA:lysine N6-acetyltransferase D 2.3.1.307 6-diazo-5-oxo-L-norleucine Nalpha-acetyltranferase D 2.3.1.308 tubulin N-terminal N-acetyltransferase NAT9 D 2.3.1.309 [beta-tubulin]-L-lysine N-acetyltransferase D 2.3.1.310 benzoylsuccinyl-CoA thiolase D 2.3.1.311 tRNA carboxymethyluridine synthase D 2.3.1.312 D-glutamate N-acetyltransferase D 2.3.1.313 NAD-dependent lipoamidase E CH54_108 sir2 family protein K12410 cobB; NAD-dependent protein deacetylase/lipoamidase [EC:2.3.1.286 2.3.1.313] C 2.3.2 Aminoacyltransferases D 2.3.2.1 D-glutamyltransferase D 2.3.2.2 gamma-glutamyltransferase E CH54_3650 ggt; gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] D 2.3.2.3 lysyltransferase D 2.3.2.5 glutaminyl-peptide cyclotransferase D 2.3.2.6 lysine/arginine leucyltransferase E CH54_4074 aat; leucyl/phenylalanyl-tRNA--protein transferase K00684 aat; leucyl/phenylalanyl-tRNA---protein transferase [EC:2.3.2.6] D 2.3.2.7 aspartyltransferase D 2.3.2.8 arginyltransferase D 2.3.2.9 agaritine gamma-glutamyltransferase D 2.3.2.10 UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase D 2.3.2.11 alanylphosphatidylglycerol synthase D 2.3.2.12 peptidyltransferase D 2.3.2.13 protein-glutamine gamma-glutamyltransferase D 2.3.2.14 D-alanine gamma-glutamyltransferase D 2.3.2.15 glutathione gamma-glutamylcysteinyltransferase D 2.3.2.16 lipid II:glycine glycyltransferase D 2.3.2.17 N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-(N6-glycyl)-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine:glycine glycyltransferase D 2.3.2.18 N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-(N6-triglycine)-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine:glycine glycyltransferase D 2.3.2.19 ribostamycin:4-(gamma-L-glutamylamino)-(S)-2-hydroxybutanoyl-[BtrI acyl-carrier protein] 4-(gamma-L-glutamylamino)-(S)-2-hydroxybutanoate transferase D 2.3.2.20 cyclo(L-leucyl-L-phenylalanyl) synthase D 2.3.2.21 cyclo(L-tyrosyl-L-tyrosyl) synthase D 2.3.2.22 cyclo(L-leucyl-L-leucyl) synthase D 2.3.2.23 E2 ubiquitin-conjugating enzyme D 2.3.2.24 (E3-independent) E2 ubiquitin-conjugating enzyme D 2.3.2.25 N-terminal E2 ubiquitin-conjugating enzyme D 2.3.2.26 HECT-type E3 ubiquitin transferase D 2.3.2.27 RING-type E3 ubiquitin transferase D 2.3.2.28 L-allo-isoleucyltransferase D 2.3.2.29 aspartate/glutamate leucyltransferase D 2.3.2.30 L-ornithine Nalpha-acyltransferase D 2.3.2.31 RBR-type E3 ubiquitin transferase D 2.3.2.32 cullin-RING-type E3 NEDD8 transferase D 2.3.2.33 RCR-type E3 ubiquitin transferase D 2.3.2.34 E2 NEDD8-conjugating enzyme D 2.3.2.35 capsaicin synthase D 2.3.2.36 RING-type E3 ubiquitin transferase (cysteine targeting) D 2.3.2.37 ergosteryl-3beta-O-L-aspartate synthase C 2.3.3 Acyl groups converted into alkyl groups on transfer D 2.3.3.1 citrate (Si)-synthase E CH54_1152 gltA; citrate (Si)-synthase K01647 CS; citrate synthase [EC:2.3.3.1] D 2.3.3.2 decylcitrate synthase D 2.3.3.3 citrate (Re)-synthase D 2.3.3.4 decylhomocitrate synthase D 2.3.3.5 2-methylcitrate synthase D 2.3.3.6 2-ethylmalate synthase D 2.3.3.7 3-ethylmalate synthase D 2.3.3.8 ATP citrate synthase D 2.3.3.9 malate synthase E CH54_2905 aceB; malate synthase A K01638 aceB; malate synthase [EC:2.3.3.9] D 2.3.3.10 hydroxymethylglutaryl-CoA synthase D 2.3.3.11 2-hydroxyglutarate synthase D 2.3.3.12 3-propylmalate synthase D 2.3.3.13 2-isopropylmalate synthase E CH54_1796 leuA; 2-isopropylmalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13] D 2.3.3.14 homocitrate synthase D 2.3.3.15 sulfoacetaldehyde acetyltransferase D 2.3.3.16 citrate synthase (unknown stereospecificity) D 2.3.3.17 methylthioalkylmalate synthase D 2.3.3.18 2-phosphinomethylmalate synthase D 2.3.3.19 2-phosphonomethylmalate synthase D 2.3.3.20 acyl-CoA:acyl-CoA alkyltransferase D 2.3.3.21 (R)-citramalate synthase D 2.3.3.22 3-carboxymethyl-3-hydroxy-acyl-[acp] synthase B 2.4 Glycosyltransferases C 2.4.1 Hexosyltransferases D 2.4.1.1 glycogen phosphorylase E CH54_2335 glgP; glycogen/starch/alpha-glucan phosphorylases family protein K00688 PYG; glycogen phosphorylase [EC:2.4.1.1] E CH54_2343 glgP; glycogen/starch/alpha-glucan phosphorylases family protein K00688 PYG; glycogen phosphorylase [EC:2.4.1.1] D 2.4.1.2 dextrin dextranase D 2.4.1.4 amylosucrase D 2.4.1.5 dextransucrase D 2.4.1.7 sucrose phosphorylase D 2.4.1.8 maltose phosphorylase D 2.4.1.9 inulosucrase D 2.4.1.10 levansucrase D 2.4.1.11 glycogen(starch) synthase D 2.4.1.12 cellulose synthase (UDP-forming) E CH54_2408 bcsA; cellulose synthase catalytic subunit K00694 bcsA; cellulose synthase (UDP-forming) [EC:2.4.1.12] D 2.4.1.13 sucrose synthase D 2.4.1.14 sucrose-phosphate synthase D 2.4.1.15 alpha,alpha-trehalose-phosphate synthase (UDP-forming) D 2.4.1.16 chitin synthase D 2.4.1.17 glucuronosyltransferase D 2.4.1.18 1,4-alpha-glucan branching enzyme E CH54_2347 glgB; 1,4-alpha-glucan branching enzyme K00700 GBE1; 1,4-alpha-glucan branching enzyme [EC:2.4.1.18] D 2.4.1.19 cyclomaltodextrin glucanotransferase D 2.4.1.20 cellobiose phosphorylase D 2.4.1.21 starch synthase (glycosyl-transferring) E CH54_2344 glgA; glycogen/starch synthase, ADP-glucose type family protein K00703 glgA; starch synthase [EC:2.4.1.21] D 2.4.1.22 lactose synthase D 2.4.1.23 sphingosine beta-galactosyltransferase D 2.4.1.24 1,4-alpha-glucan 6-alpha-glucosyltransferase D 2.4.1.25 4-alpha-glucanotransferase E CH54_2334 malQ; 4-alpha-glucanotransferase K00705 malQ; 4-alpha-glucanotransferase [EC:2.4.1.25] D 2.4.1.26 DNA alpha-glucosyltransferase D 2.4.1.27 DNA beta-glucosyltransferase D 2.4.1.28 glucosyl-DNA beta-glucosyltransferase D 2.4.1.29 cellulose synthase (GDP-forming) D 2.4.1.30 1,3-beta-oligoglucan phosphorylase D 2.4.1.31 laminaribiose phosphorylase D 2.4.1.32 glucomannan 4-beta-mannosyltransferase D 2.4.1.33 mannuronan synthase D 2.4.1.34 1,3-beta-glucan synthase D 2.4.1.35 phenol beta-glucosyltransferase D 2.4.1.36 alpha,alpha-trehalose-phosphate synthase (GDP-forming) D 2.4.1.37 fucosylgalactoside 3-alpha-galactosyltransferase D 2.4.1.38 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase D 2.4.1.39 steroid N-acetylglucosaminyltransferase D 2.4.1.40 glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase D 2.4.1.41 polypeptide N-acetylgalactosaminyltransferase D 2.4.1.43 polygalacturonate 4-alpha-galacturonosyltransferase D 2.4.1.44 lipopolysaccharide 3-alpha-galactosyltransferase D 2.4.1.46 monogalactosyldiacylglycerol synthase D 2.4.1.47 N-acylsphingosine galactosyltransferase D 2.4.1.48 heteroglycan alpha-mannosyltransferase D 2.4.1.49 cellodextrin phosphorylase D 2.4.1.50 procollagen galactosyltransferase D 2.4.1.52 poly(glycerol-phosphate) alpha-glucosyltransferase D 2.4.1.53 poly(ribitol-phosphate) beta-glucosyltransferase D 2.4.1.54 undecaprenyl-phosphate mannosyltransferase D 2.4.1.56 lipopolysaccharide N-acetylglucosaminyltransferase D 2.4.1.58 lipopolysaccharide glucosyltransferase I D 2.4.1.60 CDP-abequose:alpha-D-Man-(1->4)-alpha-L-Rha-(1->3)-alpha-D-Gal-PP-Und alpha-1,3-abequosyltransferase D 2.4.1.62 ganglioside galactosyltransferase D 2.4.1.63 linamarin synthase D 2.4.1.64 alpha,alpha-trehalose phosphorylase D 2.4.1.65 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase D 2.4.1.66 procollagen glucosyltransferase D 2.4.1.67 galactinol---raffinose galactosyltransferase D 2.4.1.68 glycoprotein 6-alpha-L-fucosyltransferase D 2.4.1.69 type 1 galactoside alpha-(1,2)-fucosyltransferase D 2.4.1.70 poly(ribitol-phosphate) alpha-N-acetylglucosaminyltransferase D 2.4.1.71 arylamine glucosyltransferase D 2.4.1.73 lipopolysaccharide glucosyltransferase II D 2.4.1.74 glycosaminoglycan galactosyltransferase D 2.4.1.78 phosphopolyprenol glucosyltransferase D 2.4.1.79 globotriaosylceramide 3-beta-N-acetylgalactosaminyltransferase D 2.4.1.80 ceramide glucosyltransferase D 2.4.1.81 flavone 7-O-beta-glucosyltransferase D 2.4.1.82 galactinol---sucrose galactosyltransferase D 2.4.1.83 dolichyl-phosphate beta-D-mannosyltransferase D 2.4.1.85 cyanohydrin beta-glucosyltransferase D 2.4.1.86 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase D 2.4.1.87 N-acetyllactosaminide 3-alpha-galactosyltransferase D 2.4.1.88 globoside alpha-N-acetylgalactosaminyltransferase D 2.4.1.90 N-acetyllactosamine synthase D 2.4.1.91 flavonol 3-O-glucosyltransferase D 2.4.1.92 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase D 2.4.1.94 protein N-acetylglucosaminyltransferase D 2.4.1.96 sn-glycerol-3-phosphate 1-galactosyltransferase D 2.4.1.97 1,3-beta-D-glucan phosphorylase D 2.4.1.99 sucrose:sucrose fructosyltransferase D 2.4.1.100 2,1-fructan:2,1-fructan 1-fructosyltransferase D 2.4.1.101 alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase D 2.4.1.102 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase D 2.4.1.103 alizarin 2-beta-glucosyltransferase D 2.4.1.104 o-dihydroxycoumarin 7-O-glucosyltransferase D 2.4.1.105 vitexin beta-glucosyltransferase D 2.4.1.106 isovitexin beta-glucosyltransferase D 2.4.1.109 dolichyl-phosphate-mannose---protein mannosyltransferase D 2.4.1.110 tRNA-queuosine alpha-mannosyltransferase D 2.4.1.111 coniferyl-alcohol glucosyltransferase D 2.4.1.113 alpha-1,4-glucan-protein synthase (ADP-forming) D 2.4.1.114 2-coumarate O-beta-glucosyltransferase D 2.4.1.115 anthocyanidin 3-O-glucosyltransferase D 2.4.1.116 cyanidin 3-O-rutinoside 5-O-glucosyltransferase D 2.4.1.117 dolichyl-phosphate beta-glucosyltransferase D 2.4.1.118 cytokinin 7-beta-glucosyltransferase D 2.4.1.120 sinapate 1-glucosyltransferase D 2.4.1.121 indole-3-acetate beta-glucosyltransferase D 2.4.1.122 N-acetylgalactosaminide beta-1,3-galactosyltransferase D 2.4.1.123 inositol 3-alpha-galactosyltransferase D 2.4.1.125 sucrose---1,6-alpha-glucan 3(6)-alpha-glucosyltransferase D 2.4.1.126 hydroxycinnamate 4-beta-glucosyltransferase D 2.4.1.127 monoterpenol beta-glucosyltransferase D 2.4.1.128 scopoletin glucosyltransferase D 2.4.1.131 GDP-Man:Man3GlcNAc2-PP-dolichol alpha-1,2-mannosyltransferase D 2.4.1.132 GDP-Man:Man1GlcNAc2-PP-dolichol alpha-1,3-mannosyltransferase D 2.4.1.133 xylosylprotein 4-beta-galactosyltransferase D 2.4.1.134 galactosylxylosylprotein 3-beta-galactosyltransferase D 2.4.1.135 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase D 2.4.1.136 gallate 1-beta-glucosyltransferase D 2.4.1.137 sn-glycerol-3-phosphate 2-alpha-galactosyltransferase D 2.4.1.138 mannotetraose 2-alpha-N-acetylglucosaminyltransferase D 2.4.1.139 maltose synthase D 2.4.1.140 alternansucrase D 2.4.1.141 N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase D 2.4.1.142 chitobiosyldiphosphodolichol beta-mannosyltransferase D 2.4.1.143 alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase D 2.4.1.144 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase D 2.4.1.145 alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase D 2.4.1.146 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase D 2.4.1.147 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase D 2.4.1.148 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase D 2.4.1.149 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase D 2.4.1.150 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase D 2.4.1.152 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase D 2.4.1.153 UDP-N-acetylglucosamine---dolichyl-phosphate N-acetylglucosaminyltransferase D 2.4.1.155 alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase D 2.4.1.156 indolylacetyl-myo-inositol galactosyltransferase D 2.4.1.158 13-hydroxydocosanoate 13-beta-glucosyltransferase D 2.4.1.159 flavonol-3-O-glucoside L-rhamnosyltransferase D 2.4.1.160 pyridoxine 5'-O-beta-D-glucosyltransferase D 2.4.1.161 oligosaccharide 4-alpha-D-glucosyltransferase D 2.4.1.162 aldose beta-D-fructosyltransferase D 2.4.1.165 N-acetylneuraminylgalactosylglucosylceramide beta-1,4-N-acetylgalactosaminyltransferase D 2.4.1.166 raffinose---raffinose alpha-galactosyltransferase D 2.4.1.167 sucrose 6F-alpha-galactosyltransferase D 2.4.1.168 xyloglucan 4-glucosyltransferase D 2.4.1.170 isoflavone 7-O-glucosyltransferase D 2.4.1.171 methyl-ONN-azoxymethanol beta-D-glucosyltransferase D 2.4.1.172 salicyl-alcohol beta-D-glucosyltransferase D 2.4.1.173 sterol 3beta-glucosyltransferase D 2.4.1.174 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase D 2.4.1.175 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase D 2.4.1.176 gibberellin beta-D-glucosyltransferase D 2.4.1.177 cinnamate beta-D-glucosyltransferase D 2.4.1.178 hydroxymandelonitrile glucosyltransferase D 2.4.1.179 lactosylceramide beta-1,3-galactosyltransferase D 2.4.1.180 lipopolysaccharide N-acetylmannosaminouronosyltransferase E CH54_2761 glycosyltransferase, WecB/TagA/CpsF family protein K02852 wecG; UDP-N-acetyl-D-mannosaminouronate:lipid I N-acetyl-D-mannosaminouronosyltransferase [EC:2.4.1.180] D 2.4.1.181 hydroxyanthraquinone glucosyltransferase D 2.4.1.182 lipid-A-disaccharide synthase E CH54_3533 lpxB; lipid-A-disaccharide synthase K00748 lpxB; lipid-A-disaccharide synthase [EC:2.4.1.182] D 2.4.1.183 alpha-1,3-glucan synthase D 2.4.1.184 galactolipid galactosyltransferase D 2.4.1.185 flavanone 7-O-beta-glucosyltransferase D 2.4.1.186 glycogenin glucosyltransferase D 2.4.1.187 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase D 2.4.1.188 N-acetylglucosaminyldiphosphoundecaprenol glucosyltransferase D 2.4.1.189 luteolin 7-O-glucuronosyltransferase D 2.4.1.190 luteolin-7-O-glucuronide 2''-O-glucuronosyltransferase D 2.4.1.191 luteolin-7-O-diglucuronide 4'-O-glucuronosyltransferase D 2.4.1.192 nuatigenin 3beta-glucosyltransferase D 2.4.1.193 sarsapogenin 3beta-glucosyltransferase D 2.4.1.194 4-hydroxybenzoate 4-O-beta-D-glucosyltransferase D 2.4.1.195 N-hydroxythioamide S-beta-glucosyltransferase D 2.4.1.196 nicotinate glucosyltransferase D 2.4.1.197 high-mannose-oligosaccharide beta-1,4-N-acetylglucosaminyltransferase D 2.4.1.198 phosphatidylinositol N-acetylglucosaminyltransferase D 2.4.1.199 beta-mannosylphosphodecaprenol---mannooligosaccharide 6-mannosyltransferase D 2.4.1.201 alpha-1,6-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase D 2.4.1.202 2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucosyltransferase D 2.4.1.203 trans-zeatin O-beta-D-glucosyltransferase D 2.4.1.205 galactogen 6beta-galactosyltransferase D 2.4.1.206 lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase D 2.4.1.207 xyloglucan:xyloglucosyl transferase D 2.4.1.208 diglucosyl diacylglycerol synthase (1,2-linking) D 2.4.1.209 cis-p-coumarate glucosyltransferase D 2.4.1.210 limonoid glucosyltransferase D 2.4.1.211 1,3-beta-galactosyl-N-acetylhexosamine phosphorylase D 2.4.1.212 hyaluronan synthase D 2.4.1.213 glucosylglycerol-phosphate synthase D 2.4.1.214 glycoprotein 3-alpha-L-fucosyltransferase D 2.4.1.215 cis-zeatin O-beta-D-glucosyltransferase D 2.4.1.216 trehalose 6-phosphate phosphorylase D 2.4.1.217 mannosyl-3-phosphoglycerate synthase D 2.4.1.218 hydroquinone glucosyltransferase D 2.4.1.219 vomilenine glucosyltransferase D 2.4.1.220 indoxyl-UDPG glucosyltransferase D 2.4.1.221 peptide-O-fucosyltransferase D 2.4.1.222 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase D 2.4.1.223 glucuronosyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase D 2.4.1.224 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase D 2.4.1.225 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase D 2.4.1.226 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase D 2.4.1.227 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase E CH54_1779 murG; undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] D 2.4.1.228 lactosylceramide 4-alpha-galactosyltransferase D 2.4.1.229 [Skp1-protein]-hydroxyproline N-acetylglucosaminyltransferase D 2.4.1.230 kojibiose phosphorylase D 2.4.1.231 alpha,alpha-trehalose phosphorylase (configuration-retaining) D 2.4.1.232 initiation-specific alpha-1,6-mannosyltransferase D 2.4.1.234 kaempferol 3-O-galactosyltransferase D 2.4.1.236 flavanone 7-O-glucoside 2''-O-beta-L-rhamnosyltransferase D 2.4.1.237 flavonol 7-O-beta-glucosyltransferase D 2.4.1.238 delphinidin 3,5-di-O-glucoside 3'-O-glucosyltransferase D 2.4.1.239 flavonol-3-O-glucoside glucosyltransferase D 2.4.1.240 flavonol-3-O-glycoside glucosyltransferase D 2.4.1.241 digalactosyldiacylglycerol synthase D 2.4.1.242 NDP-glucose---starch glucosyltransferase D 2.4.1.243 6G-fructosyltransferase D 2.4.1.244 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase D 2.4.1.245 alpha,alpha-trehalose synthase D 2.4.1.246 mannosylfructose-phosphate synthase D 2.4.1.247 beta-D-galactosyl-(1->4)-L-rhamnose phosphorylase D 2.4.1.248 cycloisomaltooligosaccharide glucanotransferase D 2.4.1.249 delphinidin 3',5'-O-glucosyltransferase D 2.4.1.250 D-inositol-3-phosphate glycosyltransferase D 2.4.1.251 GlcA-beta-(1->2)-D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphospho-ditrans,octacis-undecaprenol 4-beta-mannosyltransferase D 2.4.1.252 GDP-mannose:cellobiosyl-diphosphopolyprenol alpha-mannosyltransferase D 2.4.1.253 baicalein 7-O-glucuronosyltransferase D 2.4.1.254 cyanidin-3-O-glucoside 2''-O-glucuronosyltransferase D 2.4.1.255 protein O-GlcNAc transferase D 2.4.1.256 dolichyl-P-Glc:Glc2Man9GlcNAc2-PP-dolichol alpha-1,2-glucosyltransferase D 2.4.1.257 GDP-Man:Man2GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase D 2.4.1.258 dolichyl-P-Man:Man5GlcNAc2-PP-dolichol alpha-1,3-mannosyltransferase D 2.4.1.259 dolichyl-P-Man:Man6GlcNAc2-PP-dolichol alpha-1,2-mannosyltransferase D 2.4.1.260 dolichyl-P-Man:Man7GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase D 2.4.1.261 dolichyl-P-Man:Man8GlcNAc2-PP-dolichol alpha-1,2-mannosyltransferase D 2.4.1.262 soyasapogenol glucuronosyltransferase D 2.4.1.263 abscisate beta-glucosyltransferase D 2.4.1.264 D-Man-alpha-(1->3)-D-Glc-beta-(1->4)-D-Glc-alpha-1-diphosphoundecaprenol 2-beta-glucuronosyltransferase D 2.4.1.265 dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichol alpha-1,3-glucosyltransferase D 2.4.1.266 glucosyl-3-phosphoglycerate synthase D 2.4.1.267 dolichyl-P-Glc:Man9GlcNAc2-PP-dolichol alpha-1,3-glucosyltransferase D 2.4.1.268 glucosylglycerate synthase D 2.4.1.269 mannosylglycerate synthase D 2.4.1.270 mannosylglucosyl-3-phosphoglycerate synthase D 2.4.1.271 crocetin glucosyltransferase D 2.4.1.272 soyasapogenol B glucuronide galactosyltransferase D 2.4.1.273 soyasaponin III rhamnosyltransferase D 2.4.1.274 glucosylceramide beta-1,4-galactosyltransferase D 2.4.1.275 neolactotriaosylceramide beta-1,4-galactosyltransferase D 2.4.1.276 zeaxanthin glucosyltransferase D 2.4.1.277 10-deoxymethynolide desosaminyltransferase D 2.4.1.278 3-alpha-mycarosylerythronolide B desosaminyl transferase D 2.4.1.279 nigerose phosphorylase D 2.4.1.280 N,N'-diacetylchitobiose phosphorylase D 2.4.1.281 4-O-beta-D-mannosyl-D-glucose phosphorylase D 2.4.1.282 3-O-alpha-D-glucosyl-L-rhamnose phosphorylase D 2.4.1.283 2-deoxystreptamine N-acetyl-D-glucosaminyltransferase D 2.4.1.284 2-deoxystreptamine glucosyltransferase D 2.4.1.285 UDP-GlcNAc:ribostamycin N-acetylglucosaminyltransferase D 2.4.1.286 chalcone 4'-O-glucosyltransferase D 2.4.1.287 rhamnopyranosyl-N-acetylglucosaminyl-diphospho-decaprenol beta-1,4/1,5-galactofuranosyltransferase D 2.4.1.288 galactofuranosylgalactofuranosylrhamnosyl-N-acetylglucosaminyl-diphospho-decaprenol beta-1,5/1,6-galactofuranosyltransferase D 2.4.1.289 N-acetylglucosaminyl-diphospho-decaprenol L-rhamnosyltransferase D 2.4.1.290 N,N'-diacetylbacillosaminyl-diphospho-undecaprenol alpha-1,3-N-acetylgalactosaminyltransferase D 2.4.1.291 N-acetylgalactosamine-N,N'-diacetylbacillosaminyl-diphospho-undecaprenol 4-alpha-N-acetylgalactosaminyltransferase D 2.4.1.292 GalNAc-alpha-(1->4)-GalNAc-alpha-(1->3)-diNAcBac-PP-undecaprenol alpha-1,4-N-acetyl-D-galactosaminyltransferase D 2.4.1.293 GalNAc5-diNAcBac-PP-undecaprenol beta-1,3-glucosyltransferase D 2.4.1.294 cyanidin 3-O-galactosyltransferase D 2.4.1.295 anthocyanin 3-O-sambubioside 5-O-glucosyltransferase D 2.4.1.296 anthocyanidin 3-O-coumaroylrutinoside 5-O-glucosyltransferase D 2.4.1.297 anthocyanidin 3-O-glucoside 2''-O-glucosyltransferase D 2.4.1.298 anthocyanidin 3-O-glucoside 5-O-glucosyltransferase D 2.4.1.299 cyanidin 3-O-glucoside 5-O-glucosyltransferase (acyl-glucose) D 2.4.1.300 cyanidin 3-O-glucoside 7-O-glucosyltransferase (acyl-glucose) D 2.4.1.301 2'-deamino-2'-hydroxyneamine 1-alpha-D-kanosaminyltransferase D 2.4.1.302 L-demethylnoviosyl transferase D 2.4.1.303 UDP-Gal:alpha-D-GlcNAc-diphosphoundecaprenol beta-1,3-galactosyltransferase D 2.4.1.304 UDP-Gal:alpha-D-GlcNAc-diphosphoundecaprenol beta-1,4-galactosyltransferase D 2.4.1.305 UDP-Glc:alpha-D-GlcNAc-glucosaminyl-diphosphoundecaprenol beta-1,3-glucosyltransferase D 2.4.1.306 UDP-GalNAc:alpha-D-GalNAc-diphosphoundecaprenol alpha-1,3-N-acetylgalactosaminyltransferase D 2.4.1.308 GDP-Fuc:beta-D-Gal-1,3-alpha-D-GalNAc-1,3-alpha-GalNAc-diphosphoundecaprenol alpha-1,2-fucosyltransferase D 2.4.1.309 UDP-Gal:alpha-L-Fuc-1,2-beta-Gal-1,3-alpha-GalNAc-1,3-alpha-GalNAc-diphosphoundecaprenol alpha-1,3-galactosyltransferase D 2.4.1.310 vancomycin aglycone glucosyltransferase D 2.4.1.311 chloroorienticin B synthase D 2.4.1.312 protein O-mannose beta-1,4-N-acetylglucosaminyltransferase D 2.4.1.313 protein O-mannose beta-1,3-N-acetylgalactosaminyltransferase D 2.4.1.314 ginsenoside Rd glucosyltransferase D 2.4.1.315 diglucosyl diacylglycerol synthase (1,6-linking) D 2.4.1.316 tylactone mycaminosyltransferase D 2.4.1.317 O-mycaminosyltylonolide 6-deoxyallosyltransferase D 2.4.1.318 demethyllactenocin mycarosyltransferase D 2.4.1.319 beta-1,4-mannooligosaccharide phosphorylase D 2.4.1.320 1,4-beta-mannosyl-N-acetylglucosamine phosphorylase D 2.4.1.321 cellobionic acid phosphorylase D 2.4.1.322 devancosaminyl-vancomycin vancosaminetransferase D 2.4.1.323 7-deoxyloganetic acid glucosyltransferase D 2.4.1.324 7-deoxyloganetin glucosyltransferase D 2.4.1.325 TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase E CH54_2759 4-alpha-L-fucosyltransferase glycosyl transferase group 56 family protein K12582 wecF; dTDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase [EC:2.4.1.325] D 2.4.1.326 aklavinone 7-L-rhodosaminyltransferase D 2.4.1.327 aclacinomycin-T 2-deoxy-L-fucose transferase D 2.4.1.328 erythronolide mycarosyltransferase D 2.4.1.329 sucrose 6F-phosphate phosphorylase D 2.4.1.330 beta-D-glucosyl crocetin beta-1,6-glucosyltransferase D 2.4.1.331 8-demethyltetracenomycin C L-rhamnosyltransferase D 2.4.1.332 1,2-alpha-glucosylglycerol phosphorylase D 2.4.1.333 1,2-beta-oligoglucan phosphorylase D 2.4.1.334 1,3-alpha-oligoglucan phosphorylase D 2.4.1.335 dolichyl N-acetyl-alpha-D-glucosaminyl phosphate 3-beta-D-2,3-diacetamido-2,3-dideoxy-beta-D-glucuronosyltransferase D 2.4.1.336 monoglucosyldiacylglycerol synthase D 2.4.1.337 1,2-diacylglycerol 3-alpha-glucosyltransferase D 2.4.1.338 validoxylamine A glucosyltransferase D 2.4.1.339 beta-1,2-mannobiose phosphorylase D 2.4.1.340 1,2-beta-oligomannan phosphorylase D 2.4.1.341 alpha-1,2-colitosyltransferase D 2.4.1.342 alpha-maltose-1-phosphate synthase D 2.4.1.343 UDP-Gal:alpha-D-GlcNAc-diphosphoundecaprenol alpha-1,3-galactosyltransferase D 2.4.1.344 type 2 galactoside alpha-(1,2)-fucosyltransferase D 2.4.1.345 phosphatidyl-myo-inositol alpha-mannosyltransferase D 2.4.1.346 phosphatidyl-myo-inositol dimannoside synthase D 2.4.1.347 alpha,alpha-trehalose-phosphate synthase (ADP-forming) D 2.4.1.348 N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol 3-alpha-mannosyltransferase D 2.4.1.349 mannosyl-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol 3-alpha-mannosyltransferase D 2.4.1.350 mogroside IE synthase D 2.4.1.351 rhamnogalacturonan I rhamnosyltransferase D 2.4.1.352 glucosylglycerate phosphorylase D 2.4.1.353 sordaricin 6-deoxyaltrosyltransferase D 2.4.1.354 (R)-mandelonitrile beta-glucosyltransferase D 2.4.1.355 poly(ribitol-phosphate) beta-N-acetylglucosaminyltransferase D 2.4.1.356 glucosyl-dolichyl phosphate glucuronosyltransferase D 2.4.1.357 phlorizin synthase D 2.4.1.358 acylphloroglucinol glucosyltransferase D 2.4.1.359 glucosylglycerol phosphorylase (configuration-retaining) D 2.4.1.360 2-hydroxyflavanone C-glucosyltransferase D 2.4.1.361 GDP-mannose:di-myo-inositol-1,3'-phosphate beta-1,2-mannosyltransferase D 2.4.1.362 alpha-(1->3) branching sucrase D 2.4.1.363 ginsenoside 20-O-glucosyltransferase D 2.4.1.364 protopanaxadiol-type ginsenoside 3-O-glucosyltransferase D 2.4.1.365 protopanaxadiol-type ginsenoside-3-O-glucoside 2''-O-glucosyltransferase D 2.4.1.366 ginsenoside F1 6-O-glucosyltransferase D 2.4.1.367 ginsenoside 6-O-glucosyltransferase D 2.4.1.368 oleanolate 3-O-glucosyltransferase D 2.4.1.369 enterobactin C-glucosyltransferase D 2.4.1.370 inositol phosphorylceramide mannosyltransferase D 2.4.1.371 polymannosyl GlcNAc-diphospho-ditrans,octacis-undecaprenol 2,3-alpha-mannosylpolymerase D 2.4.1.372 mutansucrase D 2.4.1.373 alpha-(1->2) branching sucrase D 2.4.1.374 beta-1,2-mannooligosaccharide synthase D 2.4.1.375 rhamnogalacturonan I galactosyltransferase D 2.4.1.376 EGF-domain serine glucosyltransferase D 2.4.1.377 dTDP-Rha:alpha-D-Gal-diphosphoundecaprenol alpha-1,3-rhamnosyltransferase D 2.4.1.378 GDP-mannose:alpha-L-Rha-(1->3)-alpha-D-Gal-PP-Und alpha-1,4-mannosyltransferase D 2.4.1.379 GDP-Man:alpha-D-Gal-diphosphoundecaprenol alpha-1,3-mannosyltransferase D 2.4.1.380 GDP-Man:alpha-D-Man-(1->3)-alpha-D-Gal diphosphoundecaprenol alpha-1,2-mannosyltransferase D 2.4.1.381 dTDP-Rha:alpha-D-Man-(1->3)-alpha-D-Gal diphosphoundecaprenol alpha-1,2-rhamnosyltransferase D 2.4.1.382 CDP-abequose:alpha-L-Rha2OAc-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-PP-Und alpha-1,3-abequosyltransferase D 2.4.1.383 GDP-Man:alpha-L-Rha-(1->3)-alpha-D-Gal-PP-Und beta-1,4-mannosyltransferase D 2.4.1.384 NDP-glycosyltransferase D 2.4.1.385 sterol 27-beta-glucosyltransferase D 2.4.1.386 GlcNAc-beta-1,3-Gal beta-1,6-N-acetylglucosaminyltransferase (distally acting) D 2.4.1.387 isomaltosyltransferase D 2.4.1.388 glucosylgalactose phosphorylase D 2.4.1.389 solabiose phosphorylase D 2.4.1.390 4,3-alpha-glucanotransferase D 2.4.1.391 beta-1,2-glucosyltransferase D 2.4.1.392 3-O-beta-D-glucopyranosyl-beta-D-glucuronide phosphorylase D 2.4.1.393 MMP alpha-(1->4)-mannosyltransferase D 2.4.1.394 4,6-alpha-glucanotransferase (linear substrates/linear products) D 2.4.1.395 reuteransucrase D 2.4.1.396 4,6-alpha-glucanotransferase (linear and branched substrates, branched products) C 2.4.2 Pentosyltransferases D 2.4.2.1 purine-nucleoside phosphorylase E CH54_914 xapA; xanthosine phosphorylase K03783 punA; purine-nucleoside phosphorylase [EC:2.4.2.1] E CH54_1865 deoD; purine nucleoside phosphorylase K03784 deoD; purine-nucleoside phosphorylase [EC:2.4.2.1] E CH54_1601 multi-copper polyphenol oxidoreductase laccase family protein K05810 LACC1; purine-nucleoside/S-methyl-5'-thioadenosine phosphorylase / adenosine deaminase [EC:2.4.2.1 2.4.2.28 3.5.4.4] E CH54_3637 hypothetical protein K09913 ppnP; purine/pyrimidine-nucleoside phosphorylase [EC:2.4.2.1 2.4.2.2] D 2.4.2.2 pyrimidine-nucleoside phosphorylase E CH54_3637 hypothetical protein K09913 ppnP; purine/pyrimidine-nucleoside phosphorylase [EC:2.4.2.1 2.4.2.2] D 2.4.2.3 uridine phosphorylase E CH54_2835 udp; uridine phosphorylase K00757 udp; uridine phosphorylase [EC:2.4.2.3] D 2.4.2.4 thymidine phosphorylase E CH54_1867 deoA; thymidine phosphorylase K00758 deoA; thymidine phosphorylase [EC:2.4.2.4] D 2.4.2.5 nucleoside ribosyltransferase D 2.4.2.6 nucleoside deoxyribosyltransferase D 2.4.2.7 adenine phosphoribosyltransferase E CH54_3726 apt; adenine phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7] D 2.4.2.8 hypoxanthine phosphoribosyltransferase E CH54_1739 hpt; hypoxanthine phosphoribosyltransferase K00760 hprT; hypoxanthine phosphoribosyltransferase [EC:2.4.2.8] D 2.4.2.9 uracil phosphoribosyltransferase E CH54_1353 upp; uracil phosphoribosyltransferase K00761 upp; uracil phosphoribosyltransferase [EC:2.4.2.9] D 2.4.2.10 orotate phosphoribosyltransferase E CH54_2641 pyrE; orotate phosphoribosyltransferase K00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10] D 2.4.2.12 nicotinamide phosphoribosyltransferase D 2.4.2.14 amidophosphoribosyltransferase E CH54_3899 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] D 2.4.2.15 guanosine phosphorylase D 2.4.2.16 urate-ribonucleoside phosphorylase D 2.4.2.17 ATP phosphoribosyltransferase E CH54_978 hisG; ATP phosphoribosyltransferase K00765 hisG; ATP phosphoribosyltransferase [EC:2.4.2.17] D 2.4.2.18 anthranilate phosphoribosyltransferase E CH54_527 trpD; anthranilate phosphoribosyltransferase K00766 trpD; anthranilate phosphoribosyltransferase [EC:2.4.2.18] D 2.4.2.19 nicotinate-nucleotide diphosphorylase (carboxylating) E CH54_1761 nadC; nicotinate-nucleotide diphosphorylase K00767 nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19] D 2.4.2.20 dioxotetrahydropyrimidine phosphoribosyltransferase D 2.4.2.21 nicotinate-nucleotide---dimethylbenzimidazole phosphoribosyltransferase E CH54_917 cobT; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase K00768 E2.4.2.21; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [EC:2.4.2.21] D 2.4.2.22 xanthine phosphoribosyltransferase E CH54_3613 phosphoribosyl transferase domain protein K00769 gpt; xanthine phosphoribosyltransferase [EC:2.4.2.22] D 2.4.2.24 1,4-beta-D-xylan synthase D 2.4.2.25 flavone apiosyltransferase D 2.4.2.26 protein xylosyltransferase D 2.4.2.27 dTDP-dihydrostreptose---streptidine-6-phosphate dihydrostreptosyltransferase D 2.4.2.28 S-methyl-5'-thioadenosine phosphorylase E CH54_1601 multi-copper polyphenol oxidoreductase laccase family protein K05810 LACC1; purine-nucleoside/S-methyl-5'-thioadenosine phosphorylase / adenosine deaminase [EC:2.4.2.1 2.4.2.28 3.5.4.4] D 2.4.2.29 tRNA-guanosine34 preQ1 transglycosylase E CH54_3657 tgt; tRNA-guanine transglycosylase K00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29] D 2.4.2.30 NAD+ ADP-ribosyltransferase D 2.4.2.31 NAD+---protein-arginine ADP-ribosyltransferase D 2.4.2.32 dolichyl-phosphate D-xylosyltransferase D 2.4.2.33 dolichyl-xylosyl-phosphate---protein xylosyltransferase D 2.4.2.34 indolylacetylinositol arabinosyltransferase D 2.4.2.35 flavonol-3-O-glycoside xylosyltransferase D 2.4.2.36 NAD+---diphthamide ADP-ribosyltransferase D 2.4.2.37 NAD+---dinitrogen-reductase ADP-D-ribosyltransferase D 2.4.2.38 glycoprotein 2-beta-D-xylosyltransferase D 2.4.2.39 xyloglucan 6-xylosyltransferase D 2.4.2.40 zeatin O-beta-D-xylosyltransferase D 2.4.2.41 xylogalacturonan beta-1,3-xylosyltransferase D 2.4.2.42 UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase D 2.4.2.43 lipid IVA 4-amino-4-deoxy-L-arabinosyltransferase E CH54_268 dolichyl-phosphate-mannose-mannosyltransferase family protein K07264 arnT; 4-amino-4-deoxy-L-arabinose transferase [EC:2.4.2.43] D 2.4.2.44 S-methyl-5'-thioinosine phosphorylase D 2.4.2.45 decaprenyl-phosphate phosphoribosyltransferase D 2.4.2.46 galactan 5-O-arabinofuranosyltransferase D 2.4.2.47 arabinofuranan 3-O-arabinosyltransferase D 2.4.2.48 tRNA-guanine15 transglycosylase D 2.4.2.49 neamine phosphoribosyltransferase D 2.4.2.50 cyanidin 3-O-galactoside 2''-O-xylosyltransferase D 2.4.2.51 anthocyanidin 3-O-glucoside 2'''-O-xylosyltransferase D 2.4.2.52 triphosphoribosyl-dephospho-CoA synthase E CH54_858 citG; triphosphoribosyl-dephospho-CoA synthase CitG K05966 citG; triphosphoribosyl-dephospho-CoA synthase [EC:2.4.2.52] D 2.4.2.53 undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase E CH54_265 glycosyltransferase like 2 family protein K10012 arnC; undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase [EC:2.4.2.53] D 2.4.2.54 beta-ribofuranosylphenol 5'-phosphate synthase D 2.4.2.55 nicotinate D-ribonucleotide:phenol phospho-D-ribosyltransferase D 2.4.2.56 kaempferol 3-O-xylosyltransferase D 2.4.2.57 AMP phosphorylase D 2.4.2.58 hydroxyproline O-arabinosyltransferase D 2.4.2.59 sulfide-dependent adenosine diphosphate thiazole synthase D 2.4.2.60 cysteine-dependent adenosine diphosphate thiazole synthase D 2.4.2.61 alpha-dystroglycan beta1,4-xylosyltransferase D 2.4.2.62 xylosyl alpha-1,3-xylosyltransferase D 2.4.2.63 EGF-domain serine xylosyltransferase D 2.4.2.64 tRNA-guanosine34 queuine transglycosylase C 2.4.3 Sialyltransferases D 2.4.3.1 beta-galactoside alpha-(2,6)-sialyltransferase D 2.4.3.2 beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide alpha-2,3-sialyltransferase D 2.4.3.3 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase D 2.4.3.4 beta-galactoside alpha-2,3-sialyltransferase D 2.4.3.5 galactosyldiacylglycerol alpha-2,3-sialyltransferase D 2.4.3.6 N-acetyllactosaminide alpha-2,3-sialyltransferase D 2.4.3.7 alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3-N-acetylgalactosaminide 6-alpha-sialyltransferase D 2.4.3.8 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase D 2.4.3.9 lactosylceramide alpha-2,3-sialyltransferase D 2.4.3.10 N-acetylglucosaminide alpha-(2,6)-sialyltransferase C 2.4.99 Transferring other glycosyl groups D 2.4.99.12 lipid IVA 3-deoxy-D-manno-octulosonic acid transferase E CH54_2651 glycosyl transferases group 1 family protein K02527 kdtA; 3-deoxy-D-manno-octulosonic-acid transferase [EC:2.4.99.12 2.4.99.13 2.4.99.14 2.4.99.15] D 2.4.99.13 (Kdo)-lipid IVA 3-deoxy-D-manno-octulosonic acid transferase E CH54_2651 glycosyl transferases group 1 family protein K02527 kdtA; 3-deoxy-D-manno-octulosonic-acid transferase [EC:2.4.99.12 2.4.99.13 2.4.99.14 2.4.99.15] D 2.4.99.14 (Kdo)2-lipid IVA (2-8) 3-deoxy-D-manno-octulosonic acid transferase E CH54_2651 glycosyl transferases group 1 family protein K02527 kdtA; 3-deoxy-D-manno-octulosonic-acid transferase [EC:2.4.99.12 2.4.99.13 2.4.99.14 2.4.99.15] D 2.4.99.15 (Kdo)3-lipid IVA (2-4) 3-deoxy-D-manno-octulosonic acid transferase E CH54_2651 glycosyl transferases group 1 family protein K02527 kdtA; 3-deoxy-D-manno-octulosonic-acid transferase [EC:2.4.99.12 2.4.99.13 2.4.99.14 2.4.99.15] D 2.4.99.16 starch synthase (maltosyl-transferring) D 2.4.99.17 S-adenosylmethionine:tRNA ribosyltransferase-isomerase E CH54_3653 queA; tRNA ribosyltransferase-isomerase K07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17] D 2.4.99.18 dolichyl-diphosphooligosaccharide---protein glycotransferase D 2.4.99.19 undecaprenyl-diphosphooligosaccharide---protein glycotransferase D 2.4.99.20 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase D 2.4.99.21 dolichyl-phosphooligosaccharide-protein glycotransferase D 2.4.99.23 lipopolysaccharide heptosyltransferase I E CH54_2652 waaC; lipopolysaccharide heptosyltransferase I K02841 waaC; lipopolysaccharide heptosyltransferase I [EC:2.4.99.23] D 2.4.99.24 lipopolysaccharide heptosyltransferase II E CH54_2653 waaF; lipopolysaccharide heptosyltransferase II K02843 waaF; lipopolysaccharide heptosyltransferase II [EC:2.4.99.24] D 2.4.99.25 lipopolysaccharide heptosyltransferase III E CH54_1900 rfaQ; putative lipopolysaccharide heptosyltransferase III K02849 waaQ; lipopolysaccharide heptosyltransferase III [EC:2.4.99.25] D 2.4.99.26 O-antigen ligase E CH54_121 O-Antigen ligase family protein K02847 waaL; O-antigen ligase [EC:2.4.99.26] D 2.4.99.27 O-antigen polymerase Wzy E CH54_2760 wzyE family protein K02853 wzyE; enterobacterial common antigen polymerase [EC:2.4.99.27] D 2.4.99.28 peptidoglycan glycosyltransferase E CH54_3039 mtgA; monofunctional biosynthetic peptidoglycan transglycosylase K03814 mtgA; monofunctional glycosyltransferase [EC:2.4.99.28] E CH54_1724 mrcB; penicillin-binding protein 1B K05365 mrcB; penicillin-binding protein 1B [EC:2.4.99.28 3.4.16.4] E CH54_2312 penicillin-binding, 1A family protein K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] E CH54_1455 pbpC; penicillin-binding protein 1C K05367 pbpC; penicillin-binding protein 1C [EC:2.4.99.28] B 2.5 Transferring alkyl or aryl groups, other than methyl groups C 2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date) D 2.5.1.1 dimethylallyltranstransferase E CH54_3669 polyprenyl synthetase family protein K00795 ispA; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10] D 2.5.1.2 thiamine pyridinylase D 2.5.1.3 thiamine phosphate synthase E CH54_2886 thiE; thiamine-phosphate diphosphorylase K00788 thiE; thiamine-phosphate pyrophosphorylase [EC:2.5.1.3] D 2.5.1.5 galactose-6-sulfurylase D 2.5.1.6 methionine adenosyltransferase E CH54_3385 metK; methionine adenosyltransferase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6] D 2.5.1.7 UDP-N-acetylglucosamine 1-carboxyvinyltransferase E CH54_3024 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] D 2.5.1.9 riboflavin synthase E CH54_296 ribE; riboflavin synthase, alpha subunit K00793 ribE; riboflavin synthase [EC:2.5.1.9] D 2.5.1.10 (2E,6E)-farnesyl diphosphate synthase E CH54_3669 polyprenyl synthetase family protein K00795 ispA; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10] D 2.5.1.15 dihydropteroate synthase E CH54_1985 folP; dihydropteroate synthase K00796 folP; dihydropteroate synthase [EC:2.5.1.15] D 2.5.1.16 spermidine synthase E CH54_1743 speE; spermidine synthase K00797 speE; spermidine synthase [EC:2.5.1.16] D 2.5.1.17 corrinoid adenosyltransferase E CH54_501 cobO; cob(I)yrinic acid a,c-diamide adenosyltransferase K19221 cobA; cob(I)alamin adenosyltransferase [EC:2.5.1.17] D 2.5.1.18 glutathione transferase E CH54_324 hypothetical protein K00799 GST; glutathione S-transferase [EC:2.5.1.18] E CH54_2944 hypothetical protein K00799 GST; glutathione S-transferase [EC:2.5.1.18] E CH54_4024 hypothetical protein K00799 GST; glutathione S-transferase [EC:2.5.1.18] D 2.5.1.19 3-phosphoshikimate 1-carboxyvinyltransferase E CH54_4093 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase K00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19] D 2.5.1.20 rubber cis-polyprenylcistransferase D 2.5.1.21 squalene synthase D 2.5.1.22 spermine synthase D 2.5.1.23 sym-norspermidine synthase D 2.5.1.24 discadenine synthase D 2.5.1.25 tRNA-uridine aminocarboxypropyltransferase E CH54_3563 DTW domain protein K05812 DTWD2; tRNA-uridine aminocarboxypropyltransferase [EC:2.5.1.25] D 2.5.1.26 alkylglycerone-phosphate synthase D 2.5.1.27 adenylate dimethylallyltransferase (AMP-dependent) D 2.5.1.28 dimethylallylcistransferase D 2.5.1.29 geranylgeranyl diphosphate synthase D 2.5.1.30 heptaprenyl diphosphate synthase D 2.5.1.31 ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific] E CH54_3525 uppS; di-trans,poly-cis-decaprenylcistransferase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31] D 2.5.1.32 15-cis-phytoene synthase D 2.5.1.34 4-dimethylallyltryptophan synthase D 2.5.1.35 aspulvinone dimethylallyltransferase D 2.5.1.36 trihydroxypterocarpan dimethylallyltransferase D 2.5.1.38 isonocardicin synthase D 2.5.1.39 4-hydroxybenzoate polyprenyltransferase E CH54_2925 ubiA; 4-hydroxybenzoate polyprenyl transferase K03179 ubiA; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39] D 2.5.1.41 phosphoglycerol geranylgeranyltransferase D 2.5.1.42 geranylgeranylglycerol-phosphate geranylgeranyltransferase D 2.5.1.43 nicotianamine synthase D 2.5.1.44 homospermidine synthase D 2.5.1.45 homospermidine synthase (spermidine-specific) D 2.5.1.46 deoxyhypusine synthase D 2.5.1.47 cysteine synthase E CH54_1294 cysK; cysteine synthase A K01738 cysK; cysteine synthase [EC:2.5.1.47] E CH54_3697 pyridoxal-phosphate dependent enzyme family protein K01738 cysK; cysteine synthase [EC:2.5.1.47] D 2.5.1.48 cystathionine gamma-synthase E CH54_2692 metB; O-succinylhomoserine (thiol)-lyase K01739 metB; cystathionine gamma-synthase [EC:2.5.1.48] D 2.5.1.49 O-acetylhomoserine aminocarboxypropyltransferase E CH54_129 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase family protein K01740 metY; O-acetylhomoserine (thiol)-lyase [EC:2.5.1.49] D 2.5.1.50 zeatin 9-aminocarboxyethyltransferase D 2.5.1.51 beta-pyrazolylalanine synthase D 2.5.1.52 L-mimosine synthase D 2.5.1.53 uracilylalanine synthase D 2.5.1.54 3-deoxy-7-phosphoheptulonate synthase E CH54_277 3-deoxy-7-phosphoheptulonate synthase K01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54] E CH54_1607 3-deoxy-7-phosphoheptulonate synthase K01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54] E CH54_1124 3-deoxy-7-phosphoheptulonate synthase K01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54] D 2.5.1.55 3-deoxy-8-phosphooctulonate synthase E CH54_651 kdsA; 3-deoxy-8-phosphooctulonate synthase K01627 kdsA; 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase) [EC:2.5.1.55] D 2.5.1.56 N-acetylneuraminate synthase D 2.5.1.57 N-acylneuraminate-9-phosphate synthase D 2.5.1.58 protein farnesyltransferase D 2.5.1.59 protein geranylgeranyltransferase type I D 2.5.1.60 protein geranylgeranyltransferase type II D 2.5.1.61 hydroxymethylbilane synthase E CH54_2772 hemC; hydroxymethylbilane synthase K01749 hemC; hydroxymethylbilane synthase [EC:2.5.1.61] D 2.5.1.62 chlorophyll synthase D 2.5.1.63 adenosyl-fluoride synthase D 2.5.1.65 O-phosphoserine sulfhydrylase D 2.5.1.66 N2-(2-carboxyethyl)arginine synthase D 2.5.1.67 chrysanthemyl diphosphate synthase D 2.5.1.68 (2Z,6E)-farnesyl diphosphate synthase D 2.5.1.69 lavandulyl diphosphate synthase D 2.5.1.70 naringenin 8-dimethylallyltransferase D 2.5.1.71 leachianone-G 2''-dimethylallyltransferase D 2.5.1.72 quinolinate synthase E CH54_1127 nadA; quinolinate synthetase complex, A subunit K03517 nadA; quinolinate synthase [EC:2.5.1.72] D 2.5.1.73 O-phospho-L-seryl-tRNA:Cys-tRNA synthase D 2.5.1.74 1,4-dihydroxy-2-naphthoate polyprenyltransferase E CH54_2684 menA; 1,4-dihydroxy-2-naphthoate octaprenyltransferase K02548 menA; 1,4-dihydroxy-2-naphthoate polyprenyltransferase [EC:2.5.1.74] D 2.5.1.75 tRNA dimethylallyltransferase E CH54_2039 miaA; tRNA dimethylallyltransferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75] D 2.5.1.76 cysteate synthase D 2.5.1.78 6,7-dimethyl-8-ribityllumazine synthase E CH54_3664 ribH; 6,7-dimethyl-8-ribityllumazine synthase K00794 ribH; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78] D 2.5.1.79 thermospermine synthase D 2.5.1.80 7-dimethylallyltryptophan synthase D 2.5.1.81 geranylfarnesyl diphosphate synthase D 2.5.1.82 hexaprenyl diphosphate synthase [geranylgeranyl-diphosphate specific] D 2.5.1.83 hexaprenyl diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific] D 2.5.1.84 all-trans-nonaprenyl diphosphate synthase [geranyl-diphosphate specific] D 2.5.1.85 all-trans-nonaprenyl diphosphate synthase [geranylgeranyl-diphosphate specific] D 2.5.1.86 trans,polycis-decaprenyl diphosphate synthase D 2.5.1.87 ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] D 2.5.1.88 trans,polycis-polyprenyl diphosphate synthase [(2Z,6E)-farnesyl diphosphate specific] D 2.5.1.89 tritrans,polycis-undecaprenyl diphosphate synthase [geranylgeranyl-diphosphate specific] D 2.5.1.90 all-trans-octaprenyl-diphosphate synthase E CH54_1997 polyprenyl synthetase family protein K02523 ispB; octaprenyl-diphosphate synthase [EC:2.5.1.90] D 2.5.1.91 all-trans-decaprenyl-diphosphate synthase D 2.5.1.92 (2Z,6Z)-farnesyl diphosphate synthase D 2.5.1.93 4-hydroxybenzoate geranyltransferase D 2.5.1.94 adenosyl-chloride synthase D 2.5.1.95 xanthan ketal pyruvate transferase D 2.5.1.96 4,4'-diapophytoene synthase D 2.5.1.97 pseudaminic acid synthase D 2.5.1.98 Rhizobium leguminosarum exopolysaccharide glucosyl ketal-pyruvate-transferase D 2.5.1.100 fumigaclavine A dimethylallyltransferase D 2.5.1.101 N,N'-diacetyllegionaminate synthase D 2.5.1.102 geranyl-pyrophosphate---olivetolic acid geranyltransferase D 2.5.1.103 presqualene diphosphate synthase D 2.5.1.104 N1-aminopropylagmatine synthase D 2.5.1.105 7,8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase E CH54_2590 metallo-beta-lactamase superfamily protein K06897 K06897; 7,8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase [EC:2.5.1.105] D 2.5.1.106 tryprostatin B synthase D 2.5.1.107 verruculogen prenyltransferase D 2.5.1.108 2-(3-amino-3-carboxypropyl)histidine synthase D 2.5.1.109 brevianamide F prenyltransferase (deoxybrevianamide E-forming) D 2.5.1.110 12alpha,13alpha-dihydroxyfumitremorgin C prenyltransferase D 2.5.1.111 4-hydroxyphenylpyruvate 3-dimethylallyltransferase D 2.5.1.112 adenylate dimethylallyltransferase (ADP/ATP-dependent) D 2.5.1.113 [CysO sulfur-carrier protein]-thiocarboxylate-dependent cysteine synthase D 2.5.1.114 tRNAPhe (4-demethylwyosine37-C7) aminocarboxypropyltransferase D 2.5.1.115 homogentisate phytyltransferase D 2.5.1.116 homogentisate geranylgeranyltransferase D 2.5.1.117 homogentisate solanesyltransferase D 2.5.1.118 beta-(isoxazolin-5-on-2-yl)-L-alanine synthase D 2.5.1.119 beta-(isoxazolin-5-on-4-yl)-L-alanine synthase D 2.5.1.120 aminodeoxyfutalosine synthase D 2.5.1.121 5,10-dihydrophenazine-1-carboxylate 9-dimethylallyltransferase D 2.5.1.122 4-O-dimethylallyl-L-tyrosine synthase D 2.5.1.123 flaviolin linalyltransferase D 2.5.1.124 6-linalyl-2-O,3-dimethylflaviolin synthase D 2.5.1.125 7-geranyloxy-5-hydroxy-2-methoxy-3-methylnaphthalene-1,4-dione synthase D 2.5.1.126 norspermine synthase D 2.5.1.127 caldopentamine synthase D 2.5.1.128 N4-bis(aminopropyl)spermidine synthase D 2.5.1.129 flavin prenyltransferase E CH54_3900 polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylase family protein K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129] D 2.5.1.130 2-carboxy-1,4-naphthoquinone phytyltransferase D 2.5.1.131 (4-{4-[2-(gamma-L-glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine synthase D 2.5.1.132 3-deoxy-D-glycero-D-galacto-nonulopyranosonate 9-phosphate synthase D 2.5.1.133 bacteriochlorophyll a synthase D 2.5.1.134 cystathionine beta-synthase (O-acetyl-L-serine) D 2.5.1.135 validamine 7-phosphate valienyltransferase D 2.5.1.136 2-acylphloroglucinol 4-prenyltransferase D 2.5.1.137 2-acyl-4-prenylphloroglucinol 6-prenyltransferase D 2.5.1.138 coumarin 8-geranyltransferase D 2.5.1.139 umbelliferone 6-dimethylallyltransferase D 2.5.1.140 N-(2-amino-2-carboxyethyl)-L-glutamate synthase D 2.5.1.141 heme o synthase E CH54_3676 cyoE; protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141] D 2.5.1.142 nerylneryl diphosphate synthase D 2.5.1.143 pyridinium-3,5-biscarboxylic acid mononucleotide synthase D 2.5.1.144 S-sulfo-L-cysteine synthase (O-acetyl-L-serine-dependent) E CH54_1300 cysM; cysteine synthase B K12339 cysM; S-sulfo-L-cysteine synthase (O-acetyl-L-serine-dependent) [EC:2.5.1.144] D 2.5.1.145 phosphatidylglycerol---prolipoprotein diacylglyceryl transferase E CH54_3486 lgt; prolipoprotein diacylglyceryl transferase K13292 lgt; phosphatidylglycerol---prolipoprotein diacylglyceryl transferase [EC:2.5.1.145] D 2.5.1.146 3-geranyl-3-[(Z)-2-isocyanoethenyl]indole synthase D 2.5.1.147 5-amino-6-(D-ribitylamino)uracil---L-tyrosine 4-hydroxyphenyl transferase D 2.5.1.148 lycopaoctaene synthase D 2.5.1.149 lycopene elongase/hydratase (flavuxanthin-forming) D 2.5.1.150 lycopene elongase/hydratase (dihydrobisanhydrobacterioruberin-forming) D 2.5.1.151 alkylcobalamin dealkylase D 2.5.1.152 D-histidine 2-aminobutanoyltransferase D 2.5.1.153 adenosine tuberculosinyltransferase D 2.5.1.154 corrinoid adenosyltransferase EutT D 2.5.1.155 phosphoglycerol geranylfarnesyltransferase D 2.5.1.156 geranylfarnesylglycerol-phosphate geranylfarnesyltransferase D 2.5.1.157 rRNA small subunit aminocarboxypropyltransferase B 2.6 Transferring nitrogenous groups C 2.6.1 Transaminases D 2.6.1.1 aspartate transaminase E CH54_4115 aminotransferase class I and II family protein K00813 aspC; aspartate aminotransferase [EC:2.6.1.1] D 2.6.1.2 alanine transaminase E CH54_3923 aminotransferase class I and II family protein K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2] D 2.6.1.3 cysteine transaminase D 2.6.1.4 glycine transaminase D 2.6.1.5 tyrosine transaminase D 2.6.1.6 leucine transaminase D 2.6.1.7 kynurenine---oxoglutarate transaminase D 2.6.1.9 histidinol-phosphate transaminase E CH54_424 hisC; histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] E CH54_980 hisC; histidinol-phosphate transaminase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9] D 2.6.1.11 acetylornithine transaminase E CH54_2286 astC; succinylornithine transaminase family protein K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17] D 2.6.1.12 alanine---oxo-acid transaminase D 2.6.1.13 ornithine aminotransferase D 2.6.1.14 asparagine---oxo-acid transaminase D 2.6.1.15 glutamine---pyruvate transaminase D 2.6.1.16 glutamine---fructose-6-phosphate transaminase (isomerizing) E CH54_2523 glmS; glutamine-fructose-6-phosphate transaminase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] D 2.6.1.17 succinyldiaminopimelate transaminase E CH54_2286 astC; succinylornithine transaminase family protein K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17] D 2.6.1.18 beta-alanine---pyruvate transaminase D 2.6.1.19 4-aminobutyrate---2-oxoglutarate transaminase D 2.6.1.21 D-amino-acid transaminase D 2.6.1.22 (S)-3-amino-2-methylpropionate transaminase D 2.6.1.23 4-hydroxyglutamate transaminase D 2.6.1.24 diiodotyrosine transaminase D 2.6.1.26 thyroid-hormone transaminase D 2.6.1.27 tryptophan transaminase D 2.6.1.28 tryptophan---phenylpyruvate transaminase D 2.6.1.29 diamine transaminase D 2.6.1.30 pyridoxamine---pyruvate transaminase D 2.6.1.31 pyridoxamine---oxaloacetate transaminase D 2.6.1.32 valine---3-methyl-2-oxovalerate transaminase D 2.6.1.33 dTDP-4-amino-4,6-dideoxy-D-glucose transaminase D 2.6.1.34 UDP-N-acetylbacillosamine transaminase D 2.6.1.35 glycine---oxaloacetate transaminase D 2.6.1.36 L-lysine 6-transaminase D 2.6.1.37 2-aminoethylphosphonate---pyruvate transaminase D 2.6.1.38 histidine transaminase D 2.6.1.39 2-aminoadipate transaminase D 2.6.1.40 (R)-3-amino-2-methylpropionate---pyruvate transaminase D 2.6.1.41 D-methionine---pyruvate transaminase D 2.6.1.42 branched-chain-amino-acid transaminase E CH54_2729 ilvE; branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42] D 2.6.1.43 aminolevulinate transaminase D 2.6.1.44 alanine---glyoxylate transaminase D 2.6.1.45 serine---glyoxylate transaminase D 2.6.1.46 diaminobutyrate---pyruvate transaminase D 2.6.1.47 alanine---oxomalonate transaminase D 2.6.1.48 5-aminovalerate transaminase D 2.6.1.49 dihydroxyphenylalanine transaminase D 2.6.1.50 glutamine---scyllo-inositol transaminase D 2.6.1.51 serine---pyruvate transaminase D 2.6.1.52 phosphoserine transaminase E CH54_4092 serC; phosphoserine transaminase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52] D 2.6.1.54 pyridoxamine-phosphate transaminase D 2.6.1.55 taurine---2-oxoglutarate transaminase D 2.6.1.56 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol transaminase D 2.6.1.57 aromatic-amino-acid transaminase E CH54_2937 aminotransferase class I and II family protein K00832 tyrB; aromatic-amino-acid transaminase [EC:2.6.1.57] D 2.6.1.58 phenylalanine(histidine) transaminase D 2.6.1.59 dTDP-4-amino-4,6-dideoxygalactose transaminase E CH54_2757 wecE; TDP-4-keto-6-deoxy-D-glucose transaminase family protein K02805 wecE; dTDP-4-amino-4,6-dideoxygalactose transaminase [EC:2.6.1.59] D 2.6.1.60 aromatic-amino-acid---glyoxylate transaminase D 2.6.1.62 adenosylmethionine---8-amino-7-oxononanoate transaminase E CH54_1108 bioA; adenosylmethionine-8-amino-7-oxononanoate transaminase K00833 bioA; adenosylmethionine---8-amino-7-oxononanoate aminotransferase [EC:2.6.1.62] D 2.6.1.63 kynurenine---glyoxylate transaminase D 2.6.1.64 glutamine---phenylpyruvate transaminase D 2.6.1.65 N6-acetyl-beta-lysine transaminase D 2.6.1.66 valine---pyruvate transaminase E CH54_2483 aminotransferase class I and II family protein K00835 avtA; valine--pyruvate aminotransferase [EC:2.6.1.66] E CH54_3923 aminotransferase class I and II family protein K14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2] D 2.6.1.67 2-aminohexanoate transaminase D 2.6.1.70 aspartate---phenylpyruvate transaminase D 2.6.1.71 lysine---pyruvate 6-transaminase D 2.6.1.72 D-4-hydroxyphenylglycine transaminase D 2.6.1.73 methionine---glyoxylate transaminase D 2.6.1.74 cephalosporin-C transaminase D 2.6.1.75 cysteine-conjugate transaminase D 2.6.1.76 diaminobutyrate---2-oxoglutarate transaminase D 2.6.1.77 taurine---pyruvate aminotransferase D 2.6.1.78 aspartate---prephenate aminotransferase D 2.6.1.79 glutamate---prephenate aminotransferase D 2.6.1.80 nicotianamine aminotransferase D 2.6.1.81 succinylornithine transaminase E CH54_681 astC; succinylornithine transaminase family protein K00840 astC; succinylornithine aminotransferase [EC:2.6.1.81] D 2.6.1.82 putrescine---2-oxoglutarate transaminase D 2.6.1.83 LL-diaminopimelate aminotransferase D 2.6.1.84 arginine---pyruvate transaminase D 2.6.1.85 aminodeoxychorismate synthase E CH54_2287 glutamine amidotransferase of anthranilate synthase/aminodeoxychorismate synthase family protein K01664 pabA; para-aminobenzoate synthetase component II [EC:2.6.1.85] E CH54_168 pabB; aminodeoxychorismate synthase, component I K01665 pabB; para-aminobenzoate synthetase component I [EC:2.6.1.85] D 2.6.1.86 2-amino-4-deoxychorismate synthase D 2.6.1.87 UDP-4-amino-4-deoxy-L-arabinose aminotransferase E CH54_264 beta-eliminating lyase family protein K07806 arnB; UDP-4-amino-4-deoxy-L-arabinose-oxoglutarate aminotransferase [EC:2.6.1.87] D 2.6.1.88 methionine transaminase E CH54_3573 cys/Met metabolism PLP-dependent enzyme family protein K14287 ybdL; methionine transaminase [EC:2.6.1.88] D 2.6.1.89 dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose transaminase D 2.6.1.90 dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose transaminase D 2.6.1.92 UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase D 2.6.1.93 neamine transaminase D 2.6.1.94 2'-deamino-2'-hydroxyneamine transaminase D 2.6.1.95 neomycin C transaminase D 2.6.1.96 4-aminobutyrate---pyruvate transaminase D 2.6.1.97 archaeosine synthase D 2.6.1.98 UDP-2-acetamido-2-deoxy-ribo-hexuluronate aminotransferase D 2.6.1.99 L-tryptophan---pyruvate aminotransferase D 2.6.1.100 L-glutamine:2-deoxy-scyllo-inosose aminotransferase D 2.6.1.101 L-glutamine:3-amino-2,3-dideoxy-scyllo-inosose aminotransferase D 2.6.1.102 GDP-perosamine synthase D 2.6.1.103 (S)-3,5-dihydroxyphenylglycine transaminase D 2.6.1.104 3-dehydro-glucose-6-phosphate---glutamate transaminase D 2.6.1.105 lysine---8-amino-7-oxononanoate transaminase D 2.6.1.106 dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose transaminase D 2.6.1.107 beta-methylphenylalanine transaminase D 2.6.1.108 (5-formylfuran-3-yl)methyl phosphate transaminase D 2.6.1.109 8-amino-3,8-dideoxy-alpha-D-manno-octulosonate transaminase D 2.6.1.110 dTDP-4-dehydro-2,3,6-trideoxy-D-glucose 4-aminotransferase D 2.6.1.111 3-aminobutanoyl-CoA transaminase D 2.6.1.112 (S)-ureidoglycine---glyoxylate transaminase D 2.6.1.113 putrescine---pyruvate transaminase D 2.6.1.114 8-demethyl-8-aminoriboflavin-5'-phosphate synthase D 2.6.1.115 5-hydroxydodecatetraenal 1-aminotransferase D 2.6.1.116 6-aminohexanoate aminotransferase D 2.6.1.117 L-glutamine---4-(methylsulfanyl)-2-oxobutanoate aminotransferase D 2.6.1.118 [amino-group carrier protein]-gamma-(L-lysyl)-L-glutamate aminotransferase D 2.6.1.119 vanillin aminotransferase D 2.6.1.120 beta-alanine---2-oxoglutarate transaminase D 2.6.1.121 8-amino-7-oxononanoate carboxylating dehydrogenase D 2.6.1.122 UDP-N-acetyl-3-dehydro-alpha-D-glucosamine 3-aminotranferase D 2.6.1.123 4-amino-4-deoxychorismate synthase (2-amino-4-deoxychorismate-forming) D 2.6.1.124 [amino-group carrier protein]-gamma-(L-ornithyl)-L-glutamate aminotransferase C 2.6.3 Oximinotransferases D 2.6.3.1 oximinotransferase C 2.6.99 Transferring other nitrogenous groups D 2.6.99.1 dATP(dGTP)---DNA purinetransferase D 2.6.99.2 pyridoxine 5'-phosphate synthase E CH54_1496 pdxJ; pyridoxine 5'-phosphate synthase K03474 pdxJ; pyridoxine 5-phosphate synthase [EC:2.6.99.2] D 2.6.99.3 O-ureido-L-serine synthase B 2.7 Transferring phosphorus-containing groups C 2.7.1 Phosphotransferases with an alcohol group as acceptor D 2.7.1.1 hexokinase D 2.7.1.2 glucokinase E CH54_1272 glk; glucokinase K00845 glk; glucokinase [EC:2.7.1.2] D 2.7.1.3 ketohexokinase D 2.7.1.4 fructokinase E CH54_3639 glucokinase family protein K00847 E2.7.1.4; fructokinase [EC:2.7.1.4] D 2.7.1.5 rhamnulokinase D 2.7.1.6 galactokinase E CH54_1120 galK; galactokinase K00849 galK; galactokinase [EC:2.7.1.6] D 2.7.1.7 mannokinase D 2.7.1.8 glucosamine kinase D 2.7.1.10 phosphoglucokinase D 2.7.1.11 6-phosphofructokinase E CH54_2671 pfkA; 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] D 2.7.1.12 gluconokinase E CH54_2358 carbohydrate kinase, thermoresistant glucokinase family protein K00851 idnK; gluconokinase [EC:2.7.1.12] E CH54_3941 carbohydrate kinase, thermoresistant glucokinase family protein K00851 idnK; gluconokinase [EC:2.7.1.12] D 2.7.1.13 dehydrogluconokinase D 2.7.1.14 sedoheptulokinase D 2.7.1.15 ribokinase E CH54_2547 rbsK; ribokinase K00852 rbsK; ribokinase [EC:2.7.1.15] D 2.7.1.16 ribulokinase E CH54_456 araB; ribulokinase K00853 araB; L-ribulokinase [EC:2.7.1.16] D 2.7.1.17 xylulokinase E CH54_2445 xylB; xylulokinase K00854 xylB; xylulokinase [EC:2.7.1.17] D 2.7.1.18 phosphoribokinase D 2.7.1.19 phosphoribulokinase E CH54_2282 phosphoribulokinase / Uridine kinase family protein K00855 PRK; phosphoribulokinase [EC:2.7.1.19] D 2.7.1.20 adenosine kinase D 2.7.1.21 thymidine kinase E CH54_554 thymidine kinase family protein K00857 tdk; thymidine kinase [EC:2.7.1.21] D 2.7.1.22 ribosylnicotinamide kinase E CH54_1860 nicotinamide-nucleotide adenylyltransferase K06211 nadR; HTH-type transcriptional regulator, transcriptional repressor of NAD biosynthesis genes [EC:2.7.7.1 2.7.1.22] D 2.7.1.23 NAD+ kinase E CH54_1513 ATP-NAD kinase family protein K00858 ppnK; NAD+ kinase [EC:2.7.1.23] D 2.7.1.24 dephospho-CoA kinase E CH54_1766 coaE; dephospho-CoA kinase K00859 coaE; dephospho-CoA kinase [EC:2.7.1.24] D 2.7.1.25 adenylyl-sulfate kinase E CH54_1692 cysC; adenylyl-sulfate kinase K00860 cysC; adenylylsulfate kinase [EC:2.7.1.25] D 2.7.1.26 riboflavin kinase E CH54_1833 ribF; riboflavin biosynthesis protein RibF K11753 ribF; riboflavin kinase / FMN adenylyltransferase [EC:2.7.1.26 2.7.7.2] D 2.7.1.27 erythritol kinase (D-erythritol 4-phosphate-forming) D 2.7.1.28 triokinase D 2.7.1.29 glycerone kinase D 2.7.1.30 glycerol kinase E CH54_2680 glpK; glycerol kinase K00864 glpK; glycerol kinase [EC:2.7.1.30] D 2.7.1.31 glycerate 3-kinase D 2.7.1.32 choline kinase D 2.7.1.33 pantothenate kinase E CH54_2864 coaA; pantothenate kinase K00867 coaA; type I pantothenate kinase [EC:2.7.1.33] D 2.7.1.34 pantetheine kinase D 2.7.1.35 pyridoxal kinase E CH54_323 pyridoxal kinase K00868 pdxK; pyridoxine kinase [EC:2.7.1.35] D 2.7.1.36 mevalonate kinase D 2.7.1.39 homoserine kinase E CH54_1847 thrB; homoserine kinase K00872 thrB; homoserine kinase [EC:2.7.1.39] D 2.7.1.40 pyruvate kinase E CH54_291 pyk; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] E CH54_614 pyk; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40] D 2.7.1.41 glucose-1-phosphate phosphodismutase D 2.7.1.42 riboflavin phosphotransferase D 2.7.1.43 glucuronokinase D 2.7.1.44 galacturonokinase D 2.7.1.45 2-dehydro-3-deoxygluconokinase E CH54_2399 pfkB carbohydrate kinase family protein K00874 kdgK; 2-dehydro-3-deoxygluconokinase [EC:2.7.1.45] D 2.7.1.46 L-arabinokinase D 2.7.1.47 D-ribulokinase D 2.7.1.48 uridine/cytidine kinase E CH54_993 udk; uridine kinase K00876 udk; uridine kinase [EC:2.7.1.48] D 2.7.1.49 hydroxymethylpyrimidine kinase E CH54_1385 thiD; hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase K00941 thiD; hydroxymethylpyrimidine/phosphomethylpyrimidine kinase [EC:2.7.1.49 2.7.4.7] D 2.7.1.50 hydroxyethylthiazole kinase D 2.7.1.51 L-fuculokinase D 2.7.1.52 fucokinase D 2.7.1.53 L-xylulokinase D 2.7.1.54 D-arabinokinase D 2.7.1.55 allose kinase D 2.7.1.56 1-phosphofructokinase E CH54_4013 pfkB; 1-phosphofructokinase K00882 fruK; 1-phosphofructokinase [EC:2.7.1.56] D 2.7.1.58 2-dehydro-3-deoxygalactonokinase D 2.7.1.59 N-acetylglucosamine kinase E CH54_107 glucokinase family protein K00884 NAGK; N-acetylglucosamine kinase [EC:2.7.1.59] D 2.7.1.60 N-acylmannosamine kinase E CH54_1308 ROK family protein K00885 nanK; N-acylmannosamine kinase [EC:2.7.1.60] D 2.7.1.61 acyl-phosphate---hexose phosphotransferase D 2.7.1.62 phosphoramidate---hexose phosphotransferase D 2.7.1.63 polyphosphate---glucose phosphotransferase D 2.7.1.64 inositol 3-kinase D 2.7.1.65 scyllo-inosamine 4-kinase D 2.7.1.66 undecaprenol kinase D 2.7.1.67 1-phosphatidylinositol 4-kinase D 2.7.1.68 1-phosphatidylinositol-4-phosphate 5-kinase D 2.7.1.71 shikimate kinase E CH54_3636 cytidylate kinase-like family protein K00891 aroK; shikimate kinase [EC:2.7.1.71] E CH54_2306 ATPase associated with various cellular activities family protein K00891 aroK; shikimate kinase [EC:2.7.1.71] D 2.7.1.72 streptomycin 6-kinase D 2.7.1.73 inosine kinase E CH54_3742 pfkB carbohydrate kinase family protein K00892 gsk; inosine kinase [EC:2.7.1.73] D 2.7.1.74 deoxycytidine kinase D 2.7.1.76 2'-deoxyadenosine kinase D 2.7.1.77 nucleoside phosphotransferase D 2.7.1.78 polynucleotide 5'-hydroxyl-kinase D 2.7.1.79 diphosphate---glycerol phosphotransferase D 2.7.1.80 diphosphate---serine phosphotransferase D 2.7.1.81 hydroxylysine kinase D 2.7.1.82 ethanolamine kinase D 2.7.1.83 pseudouridine kinase E CH54_3619 bacterial regulatory s, luxR family protein K16328 psuK; pseudouridine kinase [EC:2.7.1.83] D 2.7.1.84 alkylglycerone kinase D 2.7.1.85 beta-glucoside kinase D 2.7.1.86 NADH kinase D 2.7.1.87 streptomycin 3''-kinase D 2.7.1.88 dihydrostreptomycin-6-phosphate 3'alpha-kinase D 2.7.1.89 thiamine kinase E CH54_97 thiK; thiamine kinase K07251 thiK; thiamine kinase [EC:2.7.1.89] D 2.7.1.90 diphosphate---fructose-6-phosphate 1-phosphotransferase D 2.7.1.91 sphingosine kinase D 2.7.1.92 5-dehydro-2-deoxygluconokinase E CH54_2367 iolC; 5-dehydro-2-deoxygluconokinase K03338 iolC; 5-dehydro-2-deoxygluconokinase [EC:2.7.1.92] D 2.7.1.93 alkylglycerol kinase D 2.7.1.94 acylglycerol kinase D 2.7.1.95 kanamycin kinase D 2.7.1.100 S-methyl-5-thioribose kinase E CH54_3578 mtnK; S-methyl-5-thioribose kinase K00899 mtnK; 5-methylthioribose kinase [EC:2.7.1.100] D 2.7.1.101 tagatose kinase D 2.7.1.102 hamamelose kinase D 2.7.1.103 viomycin kinase D 2.7.1.105 6-phosphofructo-2-kinase D 2.7.1.106 glucose-1,6-bisphosphate synthase D 2.7.1.107 diacylglycerol kinase (ATP) E CH54_2927 prokaryotic diacylglycerol kinase family protein K00901 dgkA; diacylglycerol kinase (ATP) [EC:2.7.1.107] D 2.7.1.108 dolichol kinase D 2.7.1.113 deoxyguanosine kinase D 2.7.1.114 AMP---thymidine kinase D 2.7.1.118 ADP---thymidine kinase D 2.7.1.119 hygromycin-B 7''-O-kinase D 2.7.1.121 phosphoenolpyruvate---glycerone phosphotransferase E CH54_1893 dhaK; dihydroxyacetone kinase, DhaK subunit K05878 dhaK; phosphoenolpyruvate---glycerone phosphotransferase subunit DhaK [EC:2.7.1.121] E CH54_1892 dhaL; dihydroxyacetone kinase, L subunit K05879 dhaL; phosphoenolpyruvate---glycerone phosphotransferase subunit DhaL [EC:2.7.1.121] E CH54_1891 dihydroxyacetone kinase, phosphotransfer subunit K05881 dhaM; phosphoenolpyruvate---glycerone phosphotransferase subunit DhaM [EC:2.7.1.121] D 2.7.1.122 xylitol kinase D 2.7.1.127 inositol-trisphosphate 3-kinase D 2.7.1.130 tetraacyldisaccharide 4'-kinase E CH54_4100 lpxK; tetraacyldisaccharide 4'-kinase K00912 lpxK; tetraacyldisaccharide 4'-kinase [EC:2.7.1.130] D 2.7.1.134 inositol-tetrakisphosphate 1-kinase D 2.7.1.136 macrolide 2'-kinase D 2.7.1.137 phosphatidylinositol 3-kinase D 2.7.1.138 ceramide kinase D 2.7.1.140 inositol-tetrakisphosphate 5-kinase D 2.7.1.142 glycerol-3-phosphate---glucose phosphotransferase D 2.7.1.143 diphosphate-purine nucleoside kinase D 2.7.1.144 tagatose-6-phosphate kinase D 2.7.1.145 deoxynucleoside kinase D 2.7.1.146 ADP-specific phosphofructokinase D 2.7.1.147 ADP-specific glucose/glucosamine kinase D 2.7.1.148 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase E CH54_658 ispE; 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase K00919 ispE; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [EC:2.7.1.148] D 2.7.1.149 1-phosphatidylinositol-5-phosphate 4-kinase D 2.7.1.150 1-phosphatidylinositol-3-phosphate 5-kinase D 2.7.1.151 inositol-polyphosphate multikinase D 2.7.1.153 phosphatidylinositol-4,5-bisphosphate 3-kinase D 2.7.1.154 phosphatidylinositol-4-phosphate 3-kinase D 2.7.1.156 adenosylcobinamide kinase E CH54_920 cobinamide kinase / cobinamide phosphate guanyltransferase family protein K02231 cobP; adenosylcobinamide kinase / adenosylcobinamide-phosphate guanylyltransferase [EC:2.7.1.156 2.7.7.62] D 2.7.1.157 N-acetylgalactosamine kinase D 2.7.1.158 inositol-pentakisphosphate 2-kinase D 2.7.1.159 inositol-1,3,4-trisphosphate 5/6-kinase D 2.7.1.160 2'-phosphotransferase D 2.7.1.161 CTP-dependent riboflavin kinase D 2.7.1.162 N-acetylhexosamine 1-kinase D 2.7.1.163 hygromycin B 4-O-kinase D 2.7.1.164 O-phosphoseryl-tRNASec kinase D 2.7.1.165 glycerate 2-kinase E CH54_2077 glycerate kinase family protein K00865 glxK; glycerate 2-kinase [EC:2.7.1.165] D 2.7.1.166 3-deoxy-D-manno-octulosonic acid kinase D 2.7.1.167 D-glycero-beta-D-manno-heptose-7-phosphate kinase E CH54_3114 rfaE1; bifunctional protein RfaE, domain I K03272 gmhC; D-beta-D-heptose 7-phosphate kinase / D-beta-D-heptose 1-phosphate adenosyltransferase [EC:2.7.1.167 2.7.7.70] D 2.7.1.168 D-glycero-alpha-D-manno-heptose-7-phosphate kinase D 2.7.1.169 pantoate kinase D 2.7.1.170 anhydro-N-acetylmuramic acid kinase E CH54_319 hypothetical protein K09001 anmK; anhydro-N-acetylmuramic acid kinase [EC:2.7.1.170] D 2.7.1.171 protein-fructosamine 3-kinase D 2.7.1.172 protein-ribulosamine 3-kinase D 2.7.1.173 nicotinate riboside kinase D 2.7.1.174 diacylglycerol kinase (CTP) D 2.7.1.175 maltokinase D 2.7.1.176 UDP-N-acetylglucosamine kinase D 2.7.1.177 L-threonine kinase E CH54_963 hypothetical protein K16651 pduX; L-threonine kinase [EC:2.7.1.177] D 2.7.1.178 2-dehydro-3-deoxyglucono/galactono-kinase D 2.7.1.179 kanosamine kinase D 2.7.1.180 FAD:protein FMN transferase E CH54_3589 apbE family protein K03734 apbE; FAD:protein FMN transferase [EC:2.7.1.180] D 2.7.1.181 polymannosyl GlcNAc-diphospho-ditrans,octacis-undecaprenol kinase D 2.7.1.182 phytol kinase D 2.7.1.183 glycoprotein-mannosyl O6-kinase D 2.7.1.184 sulfofructose kinase D 2.7.1.185 mevalonate 3-kinase D 2.7.1.186 mevalonate-3-phosphate 5-kinase D 2.7.1.187 acarbose 7IV-phosphotransferase D 2.7.1.188 2-epi-5-epi-valiolone 7-kinase D 2.7.1.189 autoinducer-2 kinase E CH54_1901 hypothetical protein K11216 lsrK; autoinducer-2 kinase [EC:2.7.1.189] D 2.7.1.190 aminoglycoside 2''-phosphotransferase D 2.7.1.191 protein-Npi-phosphohistidine---D-mannose phosphotransferase E CH54_163 PTS system, mannose/fructose/sorbose, IIB component family protein K02794 manX; mannose PTS system EIIAB component [EC:2.7.1.191] D 2.7.1.192 protein-Npi-phosphohistidine---N-acetylmuramate phosphotransferase E CH54_3095 phosphotransferase system, EIIC family protein K11192 murP; N-acetylmuramic acid PTS system EIICB component [EC:2.7.1.192] D 2.7.1.193 protein-Npi-phosphohistidine---N-acetyl-D-glucosamine phosphotransferase E CH54_1183 nagE; PTS system, N-acetylglucosamine-specific IIBC component K02804 nagE; N-acetylglucosamine PTS system EIICBA or EIICB component [EC:2.7.1.193] D 2.7.1.194 protein-Npi-phosphohistidine---L-ascorbate phosphotransferase E CH54_3911 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 family protein K02821 ulaC; ascorbate PTS system EIIA or EIIAB component [EC:2.7.1.194] E CH54_3910 PTS system, Lactose/Cellobiose specific IIB subunit K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194] D 2.7.1.195 protein-Npi-phosphohistidine---2-O-alpha-mannosyl-D-glycerate phosphotransferase D 2.7.1.196 protein-Npi-phosphohistidine---N,N'-diacetylchitobiose phosphotransferase E CH54_3873 PTS system, Lactose/Cellobiose specific IIA subunit K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205] E CH54_1539 PTS system, Lactose/Cellobiose specific IIA subunit K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205] E CH54_3876 PTS system, Lactose/Cellobiose specific IIB subunit K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205] E CH54_1542 PTS system, lactose/cellobiose family IIB component domain protein K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205] D 2.7.1.197 protein-Npi-phosphohistidine---D-mannitol phosphotransferase E CH54_2469 mtlA; PTS system, mannitol-specific IIC component family protein K02800 mtlA; mannitol PTS system EIICBA or EIICB component [EC:2.7.1.197] D 2.7.1.198 protein-Npi-phosphohistidine---D-sorbitol phosphotransferase E CH54_1378 PTS system glucitol/sorbitol-specific IIA component family protein K02781 srlB; glucitol/sorbitol PTS system EIIA component [EC:2.7.1.198] E CH54_1377 PTS system, glucitol/sorbitol-specific, IIBC component family protein K02782 srlE; glucitol/sorbitol PTS system EIIB component [EC:2.7.1.198] D 2.7.1.199 protein-Npi-phosphohistidine---D-glucose phosphotransferase E CH54_86 ptsG; PTS system, glucose-specific IIBC component K02779 ptsG; glucose PTS system EIICB or EIICBA component [EC:2.7.1.199] E CH54_447 PTS system, glucose-like IIB component domain protein K02791 malX; maltose/glucose PTS system EIICB component [EC:2.7.1.199 2.7.1.208] D 2.7.1.200 protein-Npi-phosphohistidine---galactitol phosphotransferase D 2.7.1.201 protein-Npi-phosphohistidine---trehalose phosphotransferase E CH54_3001 treP; PTS system, trehalose-specific IIBC component K02819 treB; trehalose PTS system EIIBC or EIIBCA component [EC:2.7.1.201] D 2.7.1.202 protein-Npi-phosphohistidine---D-fructose phosphotransferase E CH54_4014 PTS system, Fru family, IIB component domain protein K02770 fruA; fructose PTS system EIIBC or EIIC component [EC:2.7.1.202] E CH54_4012 phosphocarrier, HPr family protein K11183 fruB; multiphosphoryl transfer protein [EC:2.7.1.202] D 2.7.1.203 protein-Npi-phosphohistidine---D-glucosaminate phosphotransferase D 2.7.1.204 protein-Npi-phosphohistidine---D-galactose phosphotransferase D 2.7.1.205 protein-Npi-phosphohistidine---cellobiose phosphotransferase E CH54_3873 PTS system, Lactose/Cellobiose specific IIA subunit K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205] E CH54_1539 PTS system, Lactose/Cellobiose specific IIA subunit K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205] E CH54_3876 PTS system, Lactose/Cellobiose specific IIB subunit K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205] E CH54_1542 PTS system, lactose/cellobiose family IIB component domain protein K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205] D 2.7.1.206 protein-Npi-phosphohistidine---L-sorbose phosphotransferase E CH54_1648 PTS system, mannose/fructose/sorbose family, IIA component domain protein K02812 sorF; sorbose PTS system EIIA component [EC:2.7.1.206] E CH54_1649 PTS system, mannose/fructose/sorbose, IIB component family protein K02813 sorB; sorbose PTS system EIIB component [EC:2.7.1.206] D 2.7.1.207 protein-Npi-phosphohistidine---lactose phosphotransferase D 2.7.1.208 protein-Npi-phosphohistidine---maltose phosphotransferase E CH54_3623 PTS system, alpha-glucoside-specific IIBC component domain protein K02750 glvC; alpha-glucoside PTS system EIICB component [EC:2.7.1.208 2.7.1.-] E CH54_447 PTS system, glucose-like IIB component domain protein K02791 malX; maltose/glucose PTS system EIICB component [EC:2.7.1.199 2.7.1.208] D 2.7.1.209 L-erythrulose 1-kinase D 2.7.1.210 D-erythrulose 4-kinase D 2.7.1.211 protein-Npi-phosphohistidine---sucrose phosphotransferase D 2.7.1.212 alpha-D-ribose-1-phosphate 5-kinase (ADP) D 2.7.1.213 cytidine kinase D 2.7.1.214 C7-cyclitol 7-kinase D 2.7.1.215 erythritol kinase (D-erythritol 1-phosphate-forming) D 2.7.1.216 farnesol kinase D 2.7.1.217 3-dehydrotetronate 4-kinase E CH54_716 hypothetical protein K21948 otnK; 3-dehydrotetronate 4-kinase [EC:2.7.1.217] D 2.7.1.218 fructoselysine 6-kinase D 2.7.1.219 D-threonate 4-kinase D 2.7.1.220 D-erythronate 4-kinase D 2.7.1.221 N-acetylmuramate 1-kinase D 2.7.1.222 4-hydroxytryptamine kinase D 2.7.1.223 aminoimidazole riboside kinase D 2.7.1.224 cytidine diphosphoramidate kinase D 2.7.1.225 L-serine kinase (ATP) D 2.7.1.226 L-serine kinase (ADP) D 2.7.1.227 inositol phosphorylceramide synthase D 2.7.1.228 mannosyl-inositol-phosphoceramide inositolphosphotransferase D 2.7.1.229 deoxyribokinase D 2.7.1.230 amicoumacin kinase D 2.7.1.231 3-oxoisoapionate kinase D 2.7.1.232 levoglucosan kinase D 2.7.1.233 apulose kinase D 2.7.1.234 D-tagatose-1-phosphate kinase D 2.7.1.235 lipopolysaccharide core heptose(I) kinase D 2.7.1.236 NAD+ 3'-kinase D 2.7.1.237 GTP-dependent dephospho-CoA kinase D 2.7.1.238 phenol phosphorylase D 2.7.1.239 alpha-D-ribose-1-phosphate 5-kinase (ATP) C 2.7.2 Phosphotransferases with a carboxy group as acceptor D 2.7.2.1 acetate kinase E CH54_3914 ackA; acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1] D 2.7.2.2 carbamate kinase D 2.7.2.3 phosphoglycerate kinase E CH54_3391 phosphoglycerate kinase family protein K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3] D 2.7.2.4 aspartate kinase E CH54_2913 aspartate kinase, monofunctional class K00928 lysC; aspartate kinase [EC:2.7.2.4] E CH54_1848 aspartate kinase domain protein K12524 thrA; bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3] E CH54_2693 aspartate kinase domain protein K12525 metL; bifunctional aspartokinase / homoserine dehydrogenase 2 [EC:2.7.2.4 1.1.1.3] D 2.7.2.6 formate kinase D 2.7.2.7 butyrate kinase D 2.7.2.8 acetylglutamate kinase E CH54_2698 argB; acetylglutamate kinase K00930 argB; acetylglutamate kinase [EC:2.7.2.8] D 2.7.2.10 phosphoglycerate kinase (GTP) D 2.7.2.11 glutamate 5-kinase E CH54_3616 proB; glutamate 5-kinase K00931 proB; glutamate 5-kinase [EC:2.7.2.11] D 2.7.2.12 acetate kinase (diphosphate) D 2.7.2.14 branched-chain-fatty-acid kinase D 2.7.2.15 propionate kinase E CH54_960 ackA; acetate kinase K19697 pduW; propionate kinase [EC:2.7.2.15] D 2.7.2.16 2-phosphoglycerate kinase D 2.7.2.17 [amino-group carrier protein]-L-2-aminoadipate 6-kinase D 2.7.2.18 fatty acid kinase D 2.7.2.19 [amino-group carrier protein]-L-glutamate 6-kinase C 2.7.3 Phosphotransferases with a nitrogenous group as acceptor D 2.7.3.1 guanidinoacetate kinase D 2.7.3.2 creatine kinase D 2.7.3.3 arginine kinase D 2.7.3.4 taurocyamine kinase D 2.7.3.5 lombricine kinase D 2.7.3.6 hypotaurocyamine kinase D 2.7.3.7 opheline kinase D 2.7.3.8 ammonia kinase D 2.7.3.9 phosphoenolpyruvate---protein phosphotransferase E CH54_1296 ptsP; phosphoenolpyruvate-protein phosphotransferase K08483 ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9] E CH54_3485 ptsP; phosphoenolpyruvate-protein phosphotransferase K08484 ptsP; phosphotransferase system, enzyme I, PtsP [EC:2.7.3.9] D 2.7.3.10 agmatine kinase D 2.7.3.13 glutamine kinase C 2.7.4 Phosphotransferases with a phosphate group as acceptor D 2.7.4.1 ATP-polyphosphate phosphotransferase E CH54_1361 ppk1; polyphosphate kinase 1 K00937 ppk1; polyphosphate kinase [EC:2.7.4.1] D 2.7.4.2 phosphomevalonate kinase D 2.7.4.3 adenylate kinase E CH54_3731 adenylate kinase family protein K00939 adk; adenylate kinase [EC:2.7.4.3] D 2.7.4.4 nucleoside-phosphate kinase D 2.7.4.6 nucleoside-diphosphate kinase E CH54_1453 nucleoside diphosphate kinase family protein K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] D 2.7.4.7 phosphooxymethylpyrimidine kinase E CH54_1385 thiD; hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase K00941 thiD; hydroxymethylpyrimidine/phosphomethylpyrimidine kinase [EC:2.7.1.49 2.7.4.7] D 2.7.4.8 guanylate kinase E CH54_2582 gmk; guanylate kinase K00942 gmk; guanylate kinase [EC:2.7.4.8] D 2.7.4.9 dTMP kinase E CH54_83 tmk; dTMP kinase K00943 tmk; dTMP kinase [EC:2.7.4.9] D 2.7.4.10 nucleoside-triphosphate---adenylate kinase D 2.7.4.11 (deoxy)adenylate kinase D 2.7.4.12 T2-induced deoxynucleotide kinase D 2.7.4.13 (deoxy)nucleoside-phosphate kinase D 2.7.4.14 UMP/CMP kinase D 2.7.4.15 thiamine-diphosphate kinase D 2.7.4.16 thiamine-phosphate kinase E CH54_3666 thiL; thiamine-phosphate kinase K00946 thiL; thiamine-monophosphate kinase [EC:2.7.4.16] D 2.7.4.17 3-phosphoglyceroyl-phosphate---polyphosphate phosphotransferase D 2.7.4.18 farnesyl-diphosphate kinase D 2.7.4.19 5-methyldeoxycytidine-5'-phosphate kinase D 2.7.4.20 dolichyl-diphosphate---polyphosphate phosphotransferase D 2.7.4.21 inositol-hexakisphosphate 5-kinase D 2.7.4.22 UMP kinase E CH54_3522 pyrH; UMP kinase K09903 pyrH; uridylate kinase [EC:2.7.4.22] D 2.7.4.23 ribose 1,5-bisphosphate phosphokinase E CH54_1953 phnN; phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN K05774 phnN; ribose 1,5-bisphosphokinase [EC:2.7.4.23] D 2.7.4.24 diphosphoinositol-pentakisphosphate 1-kinase D 2.7.4.25 (d)CMP kinase E CH54_4094 cmk; cytidylate kinase K00945 cmk; CMP/dCMP kinase [EC:2.7.4.25] D 2.7.4.26 isopentenyl phosphate kinase D 2.7.4.27 [pyruvate, phosphate dikinase]-phosphate phosphotransferase D 2.7.4.28 [pyruvate, water dikinase]-phosphate phosphotransferase E CH54_278 kinase/pyrophosphorylase family protein K09773 ppsR; [pyruvate, water dikinase]-phosphate phosphotransferase / [pyruvate, water dikinase] kinase [EC:2.7.4.28 2.7.11.33] D 2.7.4.29 Kdo2-lipid A phosphotransferase D 2.7.4.31 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase D 2.7.4.32 farnesyl phosphate kinase D 2.7.4.33 AMP-polyphosphate phosphotransferase D 2.7.4.34 GDP-polyphosphate phosphotransferase C 2.7.6 Diphosphotransferases D 2.7.6.1 ribose-phosphate diphosphokinase E CH54_659 prs; ribose-phosphate diphosphokinase family protein K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] D 2.7.6.2 thiamine diphosphokinase D 2.7.6.3 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase E CH54_1731 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase K00950 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3] D 2.7.6.4 nucleotide diphosphokinase D 2.7.6.5 GTP diphosphokinase E CH54_1710 RelA/SpoT family protein K00951 relA; GTP pyrophosphokinase [EC:2.7.6.5] E CH54_2580 RelA/SpoT family protein K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2] C 2.7.7 Nucleotidyltransferases D 2.7.7.1 nicotinamide-nucleotide adenylyltransferase E CH54_1860 nicotinamide-nucleotide adenylyltransferase K06211 nadR; HTH-type transcriptional regulator, transcriptional repressor of NAD biosynthesis genes [EC:2.7.7.1 2.7.1.22] D 2.7.7.2 FAD synthase E CH54_1833 ribF; riboflavin biosynthesis protein RibF K11753 ribF; riboflavin kinase / FMN adenylyltransferase [EC:2.7.1.26 2.7.7.2] D 2.7.7.3 pantetheine-phosphate adenylyltransferase E CH54_2649 coaD; pantetheine-phosphate adenylyltransferase K00954 E2.7.7.3A; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3] D 2.7.7.4 sulfate adenylyltransferase E CH54_1693 cysN; sulfate adenylyltransferase, large subunit K00956 cysN; sulfate adenylyltransferase subunit 1 [EC:2.7.7.4] E CH54_1694 cysD; sulfate adenylyltransferase, small subunit K00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4] D 2.7.7.5 sulfate adenylyltransferase (ADP) D 2.7.7.6 DNA-directed RNA polymerase E CH54_2228 rpoA; DNA-directed RNA polymerase, alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] E CH54_2880 rpoB; DNA-directed RNA polymerase, beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] E CH54_2881 rpoC; DNA-directed RNA polymerase, beta' subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] E CH54_2581 rpoZ; DNA-directed RNA polymerase, omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] D 2.7.7.7 DNA-directed DNA polymerase E CH54_2560 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] E CH54_1810 DNA polymerase family B, exonuclease domain protein K02336 polB; DNA polymerase II [EC:2.7.7.7] E CH54_3535 dnaE; DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] E CH54_2495 dnaN; DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] E CH54_1932 DNA polymerase III chi subunit, HolC family protein K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7] E CH54_1210 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] E CH54_84 holB; DNA polymerase III, delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] E CH54_1585 dnaQ; DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] E CH54_2630 exonuclease family protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] E CH54_3727 dnaX; DNA polymerase III, subunit gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] E CH54_1876 DNA polymerase III psi subunit K02344 holD; DNA polymerase III subunit psi [EC:2.7.7.7] E CH54_178 DNA polymerase III, theta subunit K02345 holE; DNA polymerase III subunit theta [EC:2.7.7.7] E CH54_3597 hypothetical protein K02346 dinB; DNA polymerase IV [EC:2.7.7.7] D 2.7.7.8 polyribonucleotide nucleotidyltransferase E CH54_1974 pnp; polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] D 2.7.7.9 UTP---glucose-1-phosphate uridylyltransferase E CH54_987 galU; UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] E CH54_988 galU; UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] D 2.7.7.10 UTP---hexose-1-phosphate uridylyltransferase D 2.7.7.11 UTP---xylose-1-phosphate uridylyltransferase D 2.7.7.12 UDP-glucose---hexose-1-phosphate uridylyltransferase E CH54_1119 galT; galactose-1-phosphate uridylyltransferase K00965 galT; UDPglucose--hexose-1-phosphate uridylyltransferase [EC:2.7.7.12] D 2.7.7.13 mannose-1-phosphate guanylyltransferase D 2.7.7.14 ethanolamine-phosphate cytidylyltransferase D 2.7.7.15 choline-phosphate cytidylyltransferase D 2.7.7.18 nicotinate-nucleotide adenylyltransferase E CH54_1211 nadD; nicotinate (nicotinamide) nucleotide adenylyltransferase K00969 nadD; nicotinate-nucleotide adenylyltransferase [EC:2.7.7.18] D 2.7.7.19 polynucleotide adenylyltransferase E CH54_1730 pcnB; poly(A) polymerase family protein K00970 pcnB; poly(A) polymerase [EC:2.7.7.19] D 2.7.7.22 mannose-1-phosphate guanylyltransferase (GDP) D 2.7.7.23 UDP-N-acetylglucosamine diphosphorylase E CH54_2524 glmU; UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase K04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157] D 2.7.7.24 glucose-1-phosphate thymidylyltransferase E CH54_2755 rfbA; glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24] D 2.7.7.27 glucose-1-phosphate adenylyltransferase E CH54_2345 glgC; glucose-1-phosphate adenylyltransferase K00975 glgC; glucose-1-phosphate adenylyltransferase [EC:2.7.7.27] E CH54_832 glgC; glucose-1-phosphate adenylyltransferase K00975 glgC; glucose-1-phosphate adenylyltransferase [EC:2.7.7.27] D 2.7.7.28 nucleoside-triphosphate-aldose-1-phosphate nucleotidyltransferase D 2.7.7.30 fucose-1-phosphate guanylyltransferase D 2.7.7.31 DNA nucleotidylexotransferase D 2.7.7.32 galactose-1-phosphate thymidylyltransferase D 2.7.7.33 glucose-1-phosphate cytidylyltransferase D 2.7.7.34 glucose-1-phosphate guanylyltransferase D 2.7.7.35 ADP ribose phosphorylase D 2.7.7.36 aldose-1-phosphate adenylyltransferase D 2.7.7.37 aldose-1-phosphate nucleotidyltransferase D 2.7.7.38 3-deoxy-manno-octulosonate cytidylyltransferase E CH54_4104 kdsB; 3-deoxy-D-manno-octulosonate cytidylyltransferase K00979 kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase) [EC:2.7.7.38] D 2.7.7.39 glycerol-3-phosphate cytidylyltransferase E CH54_3611 cytidyltransferase-like domain protein K00980 tagD; glycerol-3-phosphate cytidylyltransferase [EC:2.7.7.39] D 2.7.7.40 D-ribitol-5-phosphate cytidylyltransferase D 2.7.7.41 phosphatidate cytidylyltransferase E CH54_838 cytidylyltransferase family protein K00981 E2.7.7.41; phosphatidate cytidylyltransferase [EC:2.7.7.41] E CH54_3526 cytidylyltransferase family protein K00981 E2.7.7.41; phosphatidate cytidylyltransferase [EC:2.7.7.41] D 2.7.7.42 [glutamine synthetase] adenylyltransferase E CH54_3113 glutamate-ammonia ligase adenylyltransferase family protein K00982 glnE; [glutamine synthetase] adenylyltransferase / [glutamine synthetase]-adenylyl-L-tyrosine phosphorylase [EC:2.7.7.42 2.7.7.89] D 2.7.7.43 N-acylneuraminate cytidylyltransferase D 2.7.7.44 glucuronate-1-phosphate uridylyltransferase D 2.7.7.45 guanosine-triphosphate guanylyltransferase D 2.7.7.46 gentamicin 2''-nucleotidyltransferase D 2.7.7.47 streptomycin 3''-adenylyltransferase D 2.7.7.48 RNA-directed RNA polymerase D 2.7.7.49 RNA-directed DNA polymerase D 2.7.7.50 mRNA guanylyltransferase D 2.7.7.51 adenylylsulfate---ammonia adenylyltransferase D 2.7.7.52 RNA uridylyltransferase D 2.7.7.53 ATP adenylyltransferase D 2.7.7.56 tRNA nucleotidyltransferase E CH54_2595 rph; ribonuclease PH K00989 rph; ribonuclease PH [EC:2.7.7.56] D 2.7.7.57 N-methylphosphoethanolamine cytidylyltransferase D 2.7.7.59 [protein-PII] uridylyltransferase E CH54_3518 glnD; protein-P-II uridylyltransferase K00990 glnD; [protein-PII] uridylyltransferase [EC:2.7.7.59] D 2.7.7.60 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase E CH54_1686 ispD; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00991 ispD; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [EC:2.7.7.60] D 2.7.7.61 citrate lyase holo-[acyl-carrier protein] synthase E CH54_859 citX; holo-ACP synthase CitX K05964 citX; holo-ACP synthase [EC:2.7.7.61] D 2.7.7.62 adenosylcobinamide-phosphate guanylyltransferase E CH54_920 cobinamide kinase / cobinamide phosphate guanyltransferase family protein K02231 cobP; adenosylcobinamide kinase / adenosylcobinamide-phosphate guanylyltransferase [EC:2.7.1.156 2.7.7.62] D 2.7.7.64 UTP-monosaccharide-1-phosphate uridylyltransferase D 2.7.7.65 diguanylate cyclase E CH54_1222 diguanylate cyclase domain protein K18968 adrA; diguanylate cyclase [EC:2.7.7.65] E CH54_1365 diguanylate cyclase domain protein K21084 yegE; diguanylate cyclase [EC:2.7.7.65] D 2.7.7.66 malonate decarboxylase holo-[acyl-carrier protein] synthase D 2.7.7.67 CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase D 2.7.7.68 2-phospho-L-lactate guanylyltransferase D 2.7.7.69 GDP-L-galactose/GDP-D-glucose: hexose 1-phosphate guanylyltransferase D 2.7.7.70 D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase E CH54_3114 rfaE1; bifunctional protein RfaE, domain I K03272 gmhC; D-beta-D-heptose 7-phosphate kinase / D-beta-D-heptose 1-phosphate adenosyltransferase [EC:2.7.1.167 2.7.7.70] D 2.7.7.71 D-glycero-alpha-D-manno-heptose 1-phosphate guanylyltransferase D 2.7.7.72 CCA tRNA nucleotidyltransferase E CH54_3110 poly A polymerase head domain protein K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-] D 2.7.7.73 sulfur carrier protein ThiS adenylyltransferase E CH54_2885 thiF family protein K03148 thiF; sulfur carrier protein ThiS adenylyltransferase [EC:2.7.7.73] D 2.7.7.74 1L-myo-inositol 1-phosphate cytidylyltransferase D 2.7.7.75 molybdopterin adenylyltransferase E CH54_1843 molybdenum cofactor synthesis domain protein K03831 mogA; molybdopterin adenylyltransferase [EC:2.7.7.75] D 2.7.7.76 molybdenum cofactor cytidylyltransferase D 2.7.7.77 molybdenum cofactor guanylyltransferase E CH54_2556 mobA; molybdenum cofactor guanylyltransferase K03752 mobA; molybdenum cofactor guanylyltransferase [EC:2.7.7.77] D 2.7.7.78 GDP-D-glucose phosphorylase D 2.7.7.79 tRNAHis guanylyltransferase D 2.7.7.80 molybdopterin-synthase adenylyltransferase E CH54_1041 moeB; molybdopterin synthase sulfurylase MoeB K21029 moeB; molybdopterin-synthase adenylyltransferase [EC:2.7.7.80] D 2.7.7.81 pseudaminic acid cytidylyltransferase D 2.7.7.82 CMP-N,N'-diacetyllegionaminic acid synthase D 2.7.7.83 UDP-N-acetylgalactosamine diphosphorylase D 2.7.7.84 2'-5' oligoadenylate synthase D 2.7.7.85 diadenylate cyclase D 2.7.7.86 cyclic GMP-AMP synthase D 2.7.7.87 L-threonylcarbamoyladenylate synthase E CH54_2215 telomere recombination family protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87] D 2.7.7.88 GDP polyribonucleotidyltransferase D 2.7.7.89 [glutamine synthetase]-adenylyl-L-tyrosine phosphorylase E CH54_3113 glutamate-ammonia ligase adenylyltransferase family protein K00982 glnE; [glutamine synthetase] adenylyltransferase / [glutamine synthetase]-adenylyl-L-tyrosine phosphorylase [EC:2.7.7.42 2.7.7.89] D 2.7.7.90 8-amino-3,8-dideoxy-manno-octulosonate cytidylyltransferase D 2.7.7.91 valienol-1-phosphate guanylyltransferase D 2.7.7.92 3-deoxy-D-glycero-D-galacto-nonulopyranosonate cytidylyltransferase D 2.7.7.93 phosphonoformate cytidylyltransferase D 2.7.7.96 ADP-D-ribose pyrophosphorylase D 2.7.7.97 3-hydroxy-4-methylanthranilate adenylyltransferase D 2.7.7.99 N-acetyl-alpha-D-muramate 1-phosphate uridylyltransferase D 2.7.7.100 SAMP-activating enzyme D 2.7.7.101 DNA primase DnaG E CH54_3103 dnaG; DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101] D 2.7.7.102 DNA primase AEP D 2.7.7.103 L-glutamine-phosphate cytidylyltransferase D 2.7.7.104 2-hydroxyethylphosphonate cytidylyltransferase D 2.7.7.105 phosphoenolpyruvate guanylyltransferase D 2.7.7.106 3-phospho-D-glycerate guanylyltransferase D 2.7.7.107 (2-aminoethyl)phosphonate cytidylyltransferase D 2.7.7.108 protein adenylyltransferase E CH54_273 hypothetical protein K08997 SELENOO; protein adenylyltransferase [EC:2.7.7.108] C 2.7.8 Transferases for other substituted phosphate groups D 2.7.8.1 ethanolaminephosphotransferase D 2.7.8.2 diacylglycerol cholinephosphotransferase D 2.7.8.3 ceramide cholinephosphotransferase D 2.7.8.4 serine-phosphoethanolamine synthase D 2.7.8.5 CDP-diacylglycerol---glycerol-3-phosphate 1-phosphatidyltransferase E CH54_728 pgsA; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase K00995 pgsA; CDP-diacylglycerol---glycerol-3-phosphate 3-phosphatidyltransferase [EC:2.7.8.5] D 2.7.8.6 undecaprenyl-phosphate galactose phosphotransferase D 2.7.8.7 holo-[acyl-carrier-protein] synthase E CH54_1495 acpS; holo-[acyl-carrier-protein] synthase K00997 acpS; holo-[acyl-carrier protein] synthase [EC:2.7.8.7] D 2.7.8.8 CDP-diacylglycerol---serine O-phosphatidyltransferase E CH54_3561 phospholipase D family protein K00998 pssA; CDP-diacylglycerol---serine O-phosphatidyltransferase [EC:2.7.8.8] D 2.7.8.9 phosphomannan mannosephosphotransferase D 2.7.8.10 sphingosine cholinephosphotransferase D 2.7.8.11 CDP-diacylglycerol---inositol 3-phosphatidyltransferase D 2.7.8.12 teichoic acid poly(glycerol phosphate) polymerase D 2.7.8.13 phospho-N-acetylmuramoyl-pentapeptide-transferase E CH54_1782 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] D 2.7.8.14 CDP-ribitol ribitolphosphotransferase D 2.7.8.15 UDP-N-acetylglucosamine---dolichyl-phosphate N-acetylglucosaminephosphotransferase D 2.7.8.17 UDP-N-acetylglucosamine---lysosomal-enzyme N-acetylglucosaminephosphotransferase D 2.7.8.18 UDP-galactose---UDP-N-acetylglucosamine galactose phosphotransferase D 2.7.8.19 UDP-glucose---glycoprotein glucose phosphotransferase D 2.7.8.20 phosphatidylglycerol---membrane-oligosaccharide glycerophosphotransferase D 2.7.8.21 membrane-oligosaccharide glycerophosphotransferase D 2.7.8.22 1-alkenyl-2-acylglycerol choline phosphotransferase D 2.7.8.23 carboxyvinyl-carboxyphosphonate phosphorylmutase D 2.7.8.24 phosphatidylcholine synthase D 2.7.8.26 adenosylcobinamide-GDP ribazoletransferase E CH54_919 cobS; cobalamin 5'-phosphate synthase K02233 E2.7.8.26; adenosylcobinamide-GDP ribazoletransferase [EC:2.7.8.26] D 2.7.8.27 sphingomyelin synthase D 2.7.8.28 2-phospho-L-lactate transferase D 2.7.8.29 L-serine-phosphatidylethanolamine phosphatidyltransferase D 2.7.8.31 undecaprenyl-phosphate glucose phosphotransferase D 2.7.8.32 3-O-alpha-D-mannopyranosyl-alpha-D-mannopyranose xylosylphosphotransferase D 2.7.8.33 UDP-N-acetylglucosamine---undecaprenyl-phosphate N-acetylglucosaminephosphotransferase E CH54_2750 wecA; undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35] D 2.7.8.34 CDP-L-myo-inositol myo-inositolphosphotransferase D 2.7.8.35 UDP-N-acetylglucosamine---decaprenyl-phosphate N-acetylglucosaminephosphotransferase E CH54_2750 wecA; undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase K02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35] D 2.7.8.36 undecaprenyl phosphate N,N'-diacetylbacillosamine 1-phosphate transferase D 2.7.8.37 alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase E CH54_1951 phnL; phosphonate C-P lyase system protein PhnL K05780 phnL; alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [EC:2.7.8.37] E CH54_1948 bacterial phosphonate metabolism family protein K06164 phnI; alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnI [EC:2.7.8.37] E CH54_1947 phnH; phosphonate C-P lyase system protein PhnH K06165 phnH; alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH [EC:2.7.8.37] E CH54_1946 phnG; phosphonate C-P lyase system protein PhnG K06166 phnG; alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG [EC:2.7.8.37] D 2.7.8.38 archaetidylserine synthase D 2.7.8.39 archaetidylinositol phosphate synthase D 2.7.8.40 UDP-N-acetylgalactosamine-undecaprenyl-phosphate N-acetylgalactosaminephosphotransferase D 2.7.8.41 cardiolipin synthase (CMP-forming) D 2.7.8.42 Kdo2-lipid A phosphoethanolamine 7''-transferase E CH54_2427 hypothetical protein K12975 eptB; KDO II ethanolaminephosphotransferase [EC:2.7.8.42] D 2.7.8.43 lipid A phosphoethanolamine transferase E CH54_309 hypothetical protein K03760 eptA; lipid A ethanolaminephosphotransferase [EC:2.7.8.43] D 2.7.8.44 teichoic acid glycerol-phosphate primase D 2.7.8.45 teichoic acid glycerol-phosphate transferase E CH54_3610 Poly(glycerophosphate) glycerophosphotransferase family protein K21591 tarF; teichoic acid glycerol-phosphate transferase [EC:2.7.8.45] D 2.7.8.46 teichoic acid ribitol-phosphate primase D 2.7.8.47 teichoic acid ribitol-phosphate polymerase D 2.7.8.48 ceramide phosphoethanolamine synthase C 2.7.9 Phosphotransferases with paired acceptors D 2.7.9.1 pyruvate, phosphate dikinase D 2.7.9.2 pyruvate, water dikinase E CH54_279 ppsA; phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2] D 2.7.9.3 selenide, water dikinase E CH54_570 selD; selenide, water dikinase K01008 selD; selenide, water dikinase [EC:2.7.9.3] D 2.7.9.4 alpha-glucan, water dikinase D 2.7.9.5 phosphoglucan, water dikinase D 2.7.9.6 rifampicin phosphotransferase C 2.7.10 Protein-tyrosine kinases D 2.7.10.1 receptor protein-tyrosine kinase D 2.7.10.2 non-specific protein-tyrosine kinase D 2.7.10.3 bacterial tyrosine kinase C 2.7.11 Protein-serine/threonine kinases D 2.7.11.1 non-specific serine/threonine protein kinase E CH54_2450 hypothetical protein K07154 hipA; serine/threonine-protein kinase HipA [EC:2.7.11.1] E CH54_137 RIO1 family protein K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1] D 2.7.11.2 [pyruvate dehydrogenase (acetyl-transferring)] kinase D 2.7.11.3 dephospho-[reductase kinase] kinase D 2.7.11.4 [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase D 2.7.11.5 [isocitrate dehydrogenase (NADP+)] kinase E CH54_2907 isocitrate dehydrogenase kinase/phosphatase family protein K00906 aceK; isocitrate dehydrogenase kinase/phosphatase [EC:2.7.11.5 3.1.3.-] D 2.7.11.6 [tyrosine 3-monooxygenase] kinase D 2.7.11.7 myosin-heavy-chain kinase D 2.7.11.8 Fas-activated serine/threonine kinase D 2.7.11.9 Goodpasture-antigen-binding protein kinase D 2.7.11.10 IkappaB kinase D 2.7.11.11 cAMP-dependent protein kinase D 2.7.11.12 cGMP-dependent protein kinase D 2.7.11.13 protein kinase C D 2.7.11.14 rhodopsin kinase D 2.7.11.15 beta-adrenergic-receptor kinase D 2.7.11.16 G-protein-coupled receptor kinase D 2.7.11.17 Ca2+/calmodulin-dependent protein kinase D 2.7.11.18 myosin-light-chain kinase D 2.7.11.19 phosphorylase kinase D 2.7.11.20 elongation factor 2 kinase D 2.7.11.21 polo kinase D 2.7.11.22 cyclin-dependent kinase D 2.7.11.23 [RNA-polymerase]-subunit kinase D 2.7.11.24 mitogen-activated protein kinase D 2.7.11.25 mitogen-activated protein kinase kinase kinase D 2.7.11.26 tau-protein kinase D 2.7.11.28 tropomyosin kinase D 2.7.11.29 low-density-lipoprotein receptor kinase D 2.7.11.30 receptor protein serine/threonine kinase D 2.7.11.31 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase D 2.7.11.32 [pyruvate, phosphate dikinase] kinase D 2.7.11.33 [pyruvate, water dikinase] kinase E CH54_278 kinase/pyrophosphorylase family protein K09773 ppsR; [pyruvate, water dikinase]-phosphate phosphotransferase / [pyruvate, water dikinase] kinase [EC:2.7.4.28 2.7.11.33] D 2.7.11.34 NEK6-subfamily protein kinase D 2.7.11.35 CRIK-subfamily protein kinase C 2.7.12 Dual-specificity kinases (those acting on Ser/Thr and Tyr residues) D 2.7.12.1 dual-specificity kinase D 2.7.12.2 mitogen-activated protein kinase kinase C 2.7.13 Protein-histidine kinases D 2.7.13.1 protein-histidine pros-kinase D 2.7.13.2 protein-histidine tele-kinase D 2.7.13.3 histidine kinase E CH54_2348 histidine kinase family protein K02478 K02478; two-component system, LytTR family, sensor kinase [EC:2.7.13.3] E CH54_1269 5TMR of 5TMR-LYT family protein K02478 K02478; two-component system, LytTR family, sensor kinase [EC:2.7.13.3] E CH54_1298 HAMP domain protein K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3] E CH54_812 signal transducing histidine kinase, homodimeric domain protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] E CH54_3644 phoR; phosphate regulon sensor kinase PhoR K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3] E CH54_111 HAMP domain protein K07637 phoQ; two-component system, OmpR family, sensor histidine kinase PhoQ [EC:2.7.13.3] E CH54_2319 HAMP domain protein K07638 envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3] E CH54_372 HAMP domain protein K07639 rstB; two-component system, OmpR family, sensor histidine kinase RstB [EC:2.7.13.3] E CH54_2667 HAMP domain protein K07640 cpxA; two-component system, OmpR family, sensor histidine kinase CpxA [EC:2.7.13.3] E CH54_3416 HAMP domain protein K07641 creC; two-component system, OmpR family, sensor histidine kinase CreC [EC:2.7.13.3] E CH54_1371 HAMP domain protein K07642 baeS; two-component system, OmpR family, sensor histidine kinase BaeS [EC:2.7.13.3] E CH54_1992 HAMP domain protein K07643 basS; two-component system, OmpR family, sensor histidine kinase BasS [EC:2.7.13.3] E CH54_1167 universal stress family protein K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3] E CH54_3037 sensory box protein K07648 arcB; two-component system, OmpR family, aerobic respiration control sensor histidine kinase ArcB [EC:2.7.13.3] E CH54_686 histidine kinase family protein K07673 narX; two-component system, NarL family, nitrate/nitrite sensor histidine kinase NarX [EC:2.7.13.3] E CH54_2425 histidine kinase family protein K07675 uhpB; two-component system, NarL family, sensor histidine kinase UhpB [EC:2.7.13.3] E CH54_3968 hpt domain protein K07676 rcsD; two-component system, NarL family, sensor histidine kinase RcsD [EC:2.7.13.3] E CH54_3966 rcsC Alpha-Beta-Loop family protein K07677 rcsC; two-component system, NarL family, capsular synthesis sensor histidine kinase RcsC [EC:2.7.13.3] E CH54_1711 HAMP domain protein K07678 barA; two-component system, NarL family, sensor histidine kinase BarA [EC:2.7.13.3] E CH54_2438 bacterial regulatory s, luxR family protein K07679 evgS; two-component system, NarL family, sensor histidine kinase EvgS [EC:2.7.13.3] E CH54_46 bacterial extracellular solute-binding s, 3 family protein K07679 evgS; two-component system, NarL family, sensor histidine kinase EvgS [EC:2.7.13.3] E CH54_896 hpt domain protein K07679 evgS; two-component system, NarL family, sensor histidine kinase EvgS [EC:2.7.13.3] E CH54_864 sensory box protein K07700 dpiB; two-component system, CitB family, cit operon sensor histidine kinase CitA [EC:2.7.13.3] E CH54_718 PAS fold family protein K07701 dcuS; two-component system, CitB family, sensor histidine kinase DcuS [EC:2.7.13.3] E CH54_2565 PAS fold family protein K07708 glnL; two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3] E CH54_1483 HAMP domain protein K07711 glrK; two-component system, NtrC family, sensor histidine kinase GlrK [EC:2.7.13.3] E CH54_867 histidine kinase family protein K20263 fusK; two-component system, NarL family, sensor histidine kinase FusK [EC:2.7.13.3] C 2.7.14 Protein-arginine kinases D 2.7.14.1 protein arginine kinase C 2.7.99 Other protein kinases D 2.7.99.1 triphosphate---protein phosphotransferase B 2.8 Transferring sulfur-containing groups C 2.8.1 Sulfurtransferases D 2.8.1.1 thiosulfate sulfurtransferase E CH54_1073 rhodanese-like domain protein K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] E CH54_2337 rhodanese-like domain protein K02439 glpE; thiosulfate sulfurtransferase [EC:2.8.1.1] D 2.8.1.2 3-mercaptopyruvate sulfurtransferase E CH54_1073 rhodanese-like domain protein K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] D 2.8.1.3 thiosulfate---thiol sulfurtransferase D 2.8.1.4 tRNA uracil 4-sulfurtransferase E CH54_3671 thiI; tRNA sulfurtransferase ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4] D 2.8.1.5 thiosulfate---dithiol sulfurtransferase D 2.8.1.6 biotin synthase E CH54_1107 bioB; biotin synthase K01012 bioB; biotin synthase [EC:2.8.1.6] D 2.8.1.7 cysteine desulfurase E CH54_1467 iscS; cysteine desulfurase IscS K04487 iscS; cysteine desulfurase [EC:2.8.1.7] E CH54_287 sufS; cysteine desulfurase, SufS family protein K11717 sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16] D 2.8.1.8 lipoyl synthase E CH54_1220 lipA; lipoyl synthase K03644 lipA; lipoyl synthase [EC:2.8.1.8] D 2.8.1.9 molybdenum cofactor sulfurtransferase D 2.8.1.10 thiazole synthase E CH54_2883 thiazole biosynthesis ThiG family protein K03149 thiG; thiazole synthase [EC:2.8.1.10] D 2.8.1.11 molybdopterin synthase sulfurtransferase D 2.8.1.12 molybdopterin synthase E CH54_1096 moaE family protein K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12] D 2.8.1.13 tRNA-uridine 2-sulfurtransferase E CH54_116 trmU; tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13] D 2.8.1.14 tRNA-5-taurinomethyluridine 2-sulfurtransferase D 2.8.1.15 tRNA-5-methyluridine54 2-sulfurtransferase D 2.8.1.16 L-aspartate semialdehyde sulfurtransferase C 2.8.2 Sulfotransferases D 2.8.2.1 aryl sulfotransferase D 2.8.2.2 alcohol sulfotransferase D 2.8.2.3 amine sulfotransferase D 2.8.2.4 estrone sulfotransferase D 2.8.2.5 chondroitin 4-sulfotransferase D 2.8.2.6 choline sulfotransferase D 2.8.2.7 UDP-N-acetylgalactosamine-4-sulfate sulfotransferase D 2.8.2.8 [heparan sulfate]-glucosamine N-sulfotransferase D 2.8.2.9 tyrosine-ester sulfotransferase D 2.8.2.10 Renilla-luciferin sulfotransferase D 2.8.2.11 galactosylceramide sulfotransferase D 2.8.2.13 psychosine sulfotransferase D 2.8.2.14 bile-salt sulfotransferase D 2.8.2.15 steroid sulfotransferase D 2.8.2.16 thiol sulfotransferase D 2.8.2.17 chondroitin 6-sulfotransferase D 2.8.2.18 cortisol sulfotransferase D 2.8.2.19 triglucosylalkylacylglycerol sulfotransferase D 2.8.2.20 protein-tyrosine sulfotransferase D 2.8.2.21 keratan sulfotransferase D 2.8.2.22 aryl-sulfate sulfotransferase D 2.8.2.23 [heparan sulfate]-glucosamine 3-sulfotransferase 1 D 2.8.2.24 aromatic desulfoglucosinolate sulfotransferase D 2.8.2.25 flavonol 3-sulfotransferase D 2.8.2.26 quercetin-3-sulfate 3'-sulfotransferase D 2.8.2.27 quercetin-3-sulfate 4'-sulfotransferase D 2.8.2.28 quercetin-3,3'-bissulfate 7-sulfotransferase D 2.8.2.29 [heparan sulfate]-glucosamine 3-sulfotransferase 2 D 2.8.2.30 [heparan sulfate]-glucosamine 3-sulfotransferase 3 D 2.8.2.31 petromyzonol sulfotransferase D 2.8.2.32 scymnol sulfotransferase D 2.8.2.33 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase D 2.8.2.34 glycochenodeoxycholate sulfotransferase D 2.8.2.35 dermatan 4-sulfotransferase D 2.8.2.36 desulfo-A47934 sulfotransferase D 2.8.2.37 trehalose 2-sulfotransferase D 2.8.2.38 aliphatic desulfoglucosinolate sulfotransferase D 2.8.2.39 hydroxyjasmonate sulfotransferase D 2.8.2.40 omega-hydroxy-beta-dihydromenaquinone-9 sulfotransferase C 2.8.3 CoA-transferases D 2.8.3.1 propionate CoA-transferase D 2.8.3.2 oxalate CoA-transferase D 2.8.3.3 malonate CoA-transferase D 2.8.3.5 3-oxoacid CoA-transferase D 2.8.3.6 3-oxoadipate CoA-transferase D 2.8.3.8 acetate CoA-transferase D 2.8.3.9 butyrate---acetoacetate CoA-transferase D 2.8.3.10 citrate CoA-transferase E CH54_860 citF; citrate lyase, alpha subunit K01643 citF; citrate lyase subunit alpha / citrate CoA-transferase [EC:2.8.3.10] D 2.8.3.11 citramalate CoA-transferase D 2.8.3.12 glutaconate CoA-transferase D 2.8.3.13 succinate---hydroxymethylglutarate CoA-transferase D 2.8.3.14 5-hydroxypentanoate CoA-transferase D 2.8.3.15 succinyl-CoA:(R)-benzylsuccinate CoA-transferase D 2.8.3.16 formyl-CoA transferase D 2.8.3.17 3-(aryl)acryloyl-CoA:(R)-3-(aryl)lactate CoA-transferase D 2.8.3.18 succinyl-CoA:acetate CoA-transferase D 2.8.3.19 CoA:oxalate CoA-transferase D 2.8.3.20 succinyl-CoA---D-citramalate CoA-transferase D 2.8.3.21 L-carnitine CoA-transferase D 2.8.3.22 succinyl-CoA---L-malate CoA-transferase D 2.8.3.23 caffeate CoA-transferase D 2.8.3.24 (R)-2-hydroxy-4-methylpentanoate CoA-transferase D 2.8.3.25 bile acid CoA-transferase D 2.8.3.26 succinyl-CoA:mesaconate CoA transferase D 2.8.3.27 propanoyl-CoA:succinate CoA transferase D 2.8.3.28 phenylsuccinyl-CoA transferase C 2.8.4 Transferring alkylthio groups D 2.8.4.1 coenzyme-B sulfoethylthiotransferase D 2.8.4.2 arsenate-mycothiol transferase D 2.8.4.3 tRNA-2-methylthio-N6-dimethylallyladenosine synthase E CH54_1196 miaB; tRNA-i(6)A37 thiotransferase enzyme MiaB K06168 miaB; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3] D 2.8.4.4 [ribosomal protein uS12] (aspartate89-C3)-methylthiotransferase D 2.8.4.5 tRNA (N6-L-threonylcarbamoyladenosine37-C2)-methylthiotransferase D 2.8.4.6 S-methyl-1-thioxylulose 5-phosphate methylthiotransferase C 2.8.5 Thiosulfotransferases D 2.8.5.1 S-sulfo-L-cysteine synthase (3-phospho-L-serine-dependent) D 2.8.5.2 L-cysteine S-thiosulfotransferase B 2.9 Transferring selenium-containing groups C 2.9.1 Selenotransferases D 2.9.1.1 L-seryl-tRNASec selenium transferase E CH54_2995 beta-eliminating lyase family protein K01042 selA; L-seryl-tRNA(Ser) seleniumtransferase [EC:2.9.1.1] E CH54_2455 selA; L-seryl-tRNA(Sec) selenium transferase K01042 selA; L-seryl-tRNA(Ser) seleniumtransferase [EC:2.9.1.1] D 2.9.1.2 O-phospho-L-seryl-tRNASec:L-selenocysteinyl-tRNA synthase D 2.9.1.3 tRNA 2-selenouridine synthase B 2.10 Transferring molybdenum- or tungsten-containing groups C 2.10.1 Molybdenumtransferases or tungstentransferases with sulfide groups as acceptors D 2.10.1.1 molybdopterin molybdotransferase E CH54_1040 molybdenum cofactor synthesis domain protein K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1] # A3. Hydrolases B 3.1 Acting on ester bonds C 3.1.1 Carboxylic-ester hydrolases D 3.1.1.1 carboxylesterase D 3.1.1.2 arylesterase E CH54_3754 GDSL-like Lipase/Acylhydrolase family protein K10804 tesA; acyl-CoA thioesterase I [EC:3.1.2.- 3.1.2.2 3.1.1.2 3.1.1.5] D 3.1.1.3 triacylglycerol lipase D 3.1.1.4 phospholipase A2 E CH54_2788 phospholipase A1 family protein K01058 pldA; phospholipase A1/A2 [EC:3.1.1.32 3.1.1.4] D 3.1.1.5 lysophospholipase E CH54_2792 prolyl oligopeptidase family protein K01048 pldB; lysophospholipase [EC:3.1.1.5] E CH54_3754 GDSL-like Lipase/Acylhydrolase family protein K10804 tesA; acyl-CoA thioesterase I [EC:3.1.2.- 3.1.2.2 3.1.1.2 3.1.1.5] D 3.1.1.6 acetylesterase D 3.1.1.7 acetylcholinesterase D 3.1.1.8 cholinesterase D 3.1.1.10 tropinesterase D 3.1.1.11 pectinesterase D 3.1.1.13 sterol esterase D 3.1.1.14 chlorophyllase D 3.1.1.15 L-arabinonolactonase D 3.1.1.17 gluconolactonase D 3.1.1.19 uronolactonase D 3.1.1.20 tannase D 3.1.1.22 hydroxybutyrate-dimer hydrolase D 3.1.1.23 acylglycerol lipase D 3.1.1.24 3-oxoadipate enol-lactonase D 3.1.1.25 1,4-lactonase D 3.1.1.26 galactolipase D 3.1.1.27 4-pyridoxolactonase D 3.1.1.28 acylcarnitine hydrolase D 3.1.1.29 peptidyl-tRNA hydrolase E CH54_661 pth; aminoacyl-tRNA hydrolase K01056 PTH1; peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29] D 3.1.1.30 D-arabinonolactonase D 3.1.1.31 6-phosphogluconolactonase E CH54_1109 lactonase, 7-bladed beta-propeller family protein K07404 pgl; 6-phosphogluconolactonase [EC:3.1.1.31] E CH54_2997 arylesterase family protein K07404 pgl; 6-phosphogluconolactonase [EC:3.1.1.31] D 3.1.1.32 phospholipase A1 E CH54_2788 phospholipase A1 family protein K01058 pldA; phospholipase A1/A2 [EC:3.1.1.32 3.1.1.4] D 3.1.1.33 6-acetylglucose deacetylase D 3.1.1.34 lipoprotein lipase D 3.1.1.35 dihydrocoumarin hydrolase D 3.1.1.36 limonin-D-ring-lactonase D 3.1.1.37 steroid-lactonase D 3.1.1.38 triacetate-lactonase D 3.1.1.39 actinomycin lactonase D 3.1.1.40 orsellinate-depside hydrolase D 3.1.1.41 cephalosporin-C deacetylase D 3.1.1.42 chlorogenate hydrolase D 3.1.1.43 alpha-amino-acid esterase D 3.1.1.44 4-methyloxaloacetate esterase D 3.1.1.45 carboxymethylenebutenolidase E CH54_2834 chlorophyllase family protein K01061 E3.1.1.45; carboxymethylenebutenolidase [EC:3.1.1.45] D 3.1.1.46 deoxylimonate A-ring-lactonase D 3.1.1.47 1-alkyl-2-acetylglycerophosphocholine esterase D 3.1.1.48 fusarinine-C ornithinesterase D 3.1.1.49 sinapine esterase D 3.1.1.50 wax-ester hydrolase D 3.1.1.51 phorbol-diester hydrolase D 3.1.1.52 phosphatidylinositol deacylase D 3.1.1.53 sialate O-acetylesterase D 3.1.1.54 acetoxybutynylbithiophene deacetylase D 3.1.1.55 acetylsalicylate deacetylase D 3.1.1.56 methylumbelliferyl-acetate deacetylase D 3.1.1.57 2-pyrone-4,6-dicarboxylate lactonase D 3.1.1.58 N-acetylgalactosaminoglycan deacetylase D 3.1.1.59 juvenile-hormone esterase D 3.1.1.60 bis(2-ethylhexyl)phthalate esterase D 3.1.1.61 protein-glutamate methylesterase E CH54_807 cheB methylesterase family protein K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44] D 3.1.1.63 11-cis-retinyl-palmitate hydrolase D 3.1.1.64 retinoid isomerohydrolase D 3.1.1.65 L-rhamnono-1,4-lactonase D 3.1.1.66 5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene deacetylase D 3.1.1.67 fatty-acyl-ethyl-ester synthase D 3.1.1.68 xylono-1,4-lactonase D 3.1.1.70 cetraxate benzylesterase D 3.1.1.71 acetylalkylglycerol acetylhydrolase D 3.1.1.72 acetylxylan esterase D 3.1.1.73 feruloyl esterase D 3.1.1.74 cutinase D 3.1.1.75 poly(3-hydroxybutyrate) depolymerase D 3.1.1.76 poly(3-hydroxyoctanoate) depolymerase D 3.1.1.77 acyloxyacyl hydrolase D 3.1.1.78 polyneuridine-aldehyde esterase D 3.1.1.79 hormone-sensitive lipase D 3.1.1.80 acetylajmaline esterase D 3.1.1.81 quorum-quenching N-acyl-homoserine lactonase D 3.1.1.82 pheophorbidase D 3.1.1.83 monoterpene epsilon-lactone hydrolase D 3.1.1.84 cocaine esterase D 3.1.1.85 pimelyl-[acyl-carrier protein] methyl ester esterase E CH54_2331 bioH; pimelyl-[acyl-carrier protein] methyl ester esterase K02170 bioH; pimeloyl-[acyl-carrier protein] methyl ester esterase [EC:3.1.1.85] D 3.1.1.86 rhamnogalacturonan acetylesterase D 3.1.1.87 fumonisin B1 esterase D 3.1.1.88 pyrethroid hydrolase D 3.1.1.89 protein phosphatase methylesterase-1 D 3.1.1.90 all-trans-retinyl ester 13-cis isomerohydrolase D 3.1.1.91 2-oxo-3-(5-oxofuran-2-ylidene)propanoate lactonase D 3.1.1.92 4-sulfomuconolactone hydrolase D 3.1.1.93 mycophenolic acid acyl-glucuronide esterase D 3.1.1.94 versiconal hemiacetal acetate esterase D 3.1.1.95 aclacinomycin methylesterase D 3.1.1.96 D-aminoacyl-tRNA deacylase E CH54_2570 dtd; D-tyrosyl-tRNA(Tyr) deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96] D 3.1.1.97 methylated diphthine methylhydrolase D 3.1.1.98 [Wnt protein] O-palmitoleoyl-L-serine hydrolase D 3.1.1.99 6-deoxy-6-sulfogluconolactonase D 3.1.1.100 chlorophyllide a hydrolase D 3.1.1.101 poly(ethylene terephthalate) hydrolase D 3.1.1.102 mono(ethylene terephthalate) hydrolase D 3.1.1.103 teichoic acid D-alanine hydrolase D 3.1.1.104 5-phospho-D-xylono-1,4-lactonase D 3.1.1.105 3-O-acetylpapaveroxine carboxylesterase D 3.1.1.106 O-acetyl-ADP-ribose deacetylase D 3.1.1.107 apo-salmochelin esterase D 3.1.1.108 iron(III)-enterobactin esterase E CH54_3162 hypothetical protein K07214 fes; iron(III)-enterobactin esterase [EC:3.1.1.108] D 3.1.1.109 iron(III)-salmochelin esterase D 3.1.1.110 xylono-1,5-lactonase D 3.1.1.111 phosphatidylserine sn-1 acylhydrolase D 3.1.1.112 isoamyl acetate esterase D 3.1.1.113 ethyl acetate hydrolase D 3.1.1.114 methyl acetate hydrolase D 3.1.1.115 D-apionolactonase D 3.1.1.116 sn-1-specific diacylglycerol lipase D 3.1.1.117 (4-O-methyl)-D-glucuronate---lignin esterase D 3.1.1.118 phospholipid sn-1 acylhydrolase D 3.1.1.120 L-fucono-1,5-lactonase D 3.1.1.121 ergosteryl-3beta-O-L-aspartate hydrolase D 3.1.1.122 carbendazim hydrolysing esterase C 3.1.2 Thioester hydrolases D 3.1.2.1 acetyl-CoA hydrolase D 3.1.2.2 palmitoyl-CoA hydrolase E CH54_3754 GDSL-like Lipase/Acylhydrolase family protein K10804 tesA; acyl-CoA thioesterase I [EC:3.1.2.- 3.1.2.2 3.1.1.2 3.1.1.5] D 3.1.2.3 succinyl-CoA hydrolase D 3.1.2.4 3-hydroxyisobutyryl-CoA hydrolase D 3.1.2.5 hydroxymethylglutaryl-CoA hydrolase D 3.1.2.6 hydroxyacylglutathione hydrolase E CH54_1588 gloB; hydroxyacylglutathione hydrolase K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6] E CH54_4113 beta-lactamase superfamily domain protein K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6] D 3.1.2.7 glutathione thiolesterase D 3.1.2.10 formyl-CoA hydrolase D 3.1.2.11 acetoacetyl-CoA hydrolase D 3.1.2.12 S-formylglutathione hydrolase E CH54_1032 fghA; S-formylglutathione hydrolase K01070 frmB; S-formylglutathione hydrolase [EC:3.1.2.12] D 3.1.2.13 S-succinylglutathione hydrolase D 3.1.2.14 oleoyl-[acyl-carrier-protein] hydrolase D 3.1.2.16 citrate-lyase deacetylase D 3.1.2.17 (S)-methylmalonyl-CoA hydrolase D 3.1.2.18 ADP-dependent short-chain-acyl-CoA hydrolase D 3.1.2.19 ADP-dependent medium-chain-acyl-CoA hydrolase D 3.1.2.20 acyl-CoA hydrolase D 3.1.2.21 dodecanoyl-[acyl-carrier-protein] hydrolase D 3.1.2.22 palmitoyl[protein] hydrolase D 3.1.2.23 4-hydroxybenzoyl-CoA thioesterase D 3.1.2.25 phenylacetyl-CoA hydrolase D 3.1.2.27 choloyl-CoA hydrolase D 3.1.2.28 1,4-dihydroxy-2-naphthoyl-CoA hydrolase E CH54_282 hypothetical protein K19222 menI; 1,4-dihydroxy-2-naphthoyl-CoA hydrolase [EC:3.1.2.28] D 3.1.2.29 fluoroacetyl-CoA thioesterase D 3.1.2.30 (3S)-malyl-CoA thioesterase D 3.1.2.31 dihydromonacolin L-[lovastatin nonaketide synthase] thioesterase D 3.1.2.32 2-aminobenzoylacetyl-CoA thioesterase C 3.1.3 Phosphoric-monoester hydrolases D 3.1.3.1 alkaline phosphatase E CH54_388 alkaline phosphatase family protein K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1] D 3.1.3.2 acid phosphatase E CH54_831 histidine phosphatase super family protein K01093 appA; 4-phytase / acid phosphatase [EC:3.1.3.26 3.1.3.2] D 3.1.3.3 phosphoserine phosphatase E CH54_1863 serB; phosphoserine phosphatase SerB K01079 serB; phosphoserine phosphatase [EC:3.1.3.3] D 3.1.3.4 phosphatidate phosphatase E CH54_491 PAP2 superfamily protein K01096 pgpB; phosphatidylglycerophosphatase B [EC:3.1.3.27 3.6.1.75 3.1.3.4 3.6.1.27] D 3.1.3.5 5'-nucleotidase E CH54_1187 HAD hydrolase, IA, variant 1 family protein K02566 nagD; 5'-nucleotidase [EC:3.1.3.5] E CH54_1683 surE; 5'/3'-nucleotidase SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6] E CH54_3745 hypothetical protein K11751 ushA; 5'-nucleotidase / UDP-sugar diphosphatase [EC:3.1.3.5 3.6.1.45] D 3.1.3.6 3'-nucleotidase E CH54_1143 hypothetical protein K01119 cpdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase [EC:3.1.4.16 3.1.3.6] E CH54_2016 cpdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase K01119 cpdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase [EC:3.1.4.16 3.1.3.6] E CH54_1683 surE; 5'/3'-nucleotidase SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6] D 3.1.3.7 3'(2'),5'-bisphosphate nucleotidase E CH54_2014 cysQ; 3'(2'),5'-bisphosphate nucleotidase K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7] D 3.1.3.8 3-phytase D 3.1.3.9 glucose-6-phosphatase D 3.1.3.10 glucose-1-phosphatase E CH54_3878 histidine phosphatase super family protein K01085 agp; glucose-1-phosphatase [EC:3.1.3.10] E CH54_2568 HAD hydrolase, IA, variant 3 family protein K20866 yihX; glucose-1-phosphatase [EC:3.1.3.10] D 3.1.3.11 fructose-bisphosphatase E CH54_2679 glpX; fructose-1,6-bisphosphatase, class II K02446 glpX; fructose-1,6-bisphosphatase II [EC:3.1.3.11] E CH54_2005 fructose-1-6-bisphosphatase family protein K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11] D 3.1.3.12 trehalose-phosphatase D 3.1.3.14 methylphosphothioglycerate phosphatase D 3.1.3.15 histidinol-phosphatase E CH54_981 hisB; histidinol-phosphatase K01089 hisB; imidazoleglycerol-phosphate dehydratase / histidinol-phosphatase [EC:4.2.1.19 3.1.3.15] D 3.1.3.16 protein-serine/threonine phosphatase D 3.1.3.17 [phosphorylase] phosphatase D 3.1.3.18 phosphoglycolate phosphatase E CH54_2301 gph; phosphoglycolate phosphatase K01091 gph; phosphoglycolate phosphatase [EC:3.1.3.18] D 3.1.3.19 glycerol-2-phosphatase D 3.1.3.20 phosphoglycerate phosphatase D 3.1.3.21 glycerol-1-phosphatase D 3.1.3.22 mannitol-1-phosphatase E CH54_3917 HAD hydrolase, IA, variant 1 family protein K19270 hxpA; mannitol-1-/sugar-/sorbitol-6-phosphatase [EC:3.1.3.22 3.1.3.23 3.1.3.50] E CH54_235 HAD hydrolase, IA, variant 1 family protein K24204 hxpB; mannitol-1-/sugar-/sorbitol-6-/2-deoxyglucose-6-phosphatase [EC:3.1.3.22 3.1.3.23 3.1.3.50 3.1.3.68] D 3.1.3.23 sugar-phosphatase E CH54_3917 HAD hydrolase, IA, variant 1 family protein K19270 hxpA; mannitol-1-/sugar-/sorbitol-6-phosphatase [EC:3.1.3.22 3.1.3.23 3.1.3.50] E CH54_235 HAD hydrolase, IA, variant 1 family protein K24204 hxpB; mannitol-1-/sugar-/sorbitol-6-/2-deoxyglucose-6-phosphatase [EC:3.1.3.22 3.1.3.23 3.1.3.50 3.1.3.68] D 3.1.3.24 sucrose-phosphate phosphatase D 3.1.3.25 inositol-phosphate phosphatase E CH54_1470 inositol monophosphatase family protein K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] D 3.1.3.26 4-phytase E CH54_831 histidine phosphatase super family protein K01093 appA; 4-phytase / acid phosphatase [EC:3.1.3.26 3.1.3.2] D 3.1.3.27 phosphatidylglycerophosphatase E CH54_3667 phosphatidylglycerophosphatase A family protein K01095 pgpA; phosphatidylglycerophosphatase A [EC:3.1.3.27] E CH54_491 PAP2 superfamily protein K01096 pgpB; phosphatidylglycerophosphatase B [EC:3.1.3.27 3.6.1.75 3.1.3.4 3.6.1.27] E CH54_1488 haloacid dehalogenase-like hydrolase family protein K18697 pgpC; phosphatidylglycerophosphatase C [EC:3.1.3.27] D 3.1.3.28 ADP-phosphoglycerate phosphatase D 3.1.3.29 N-acylneuraminate-9-phosphatase D 3.1.3.32 polynucleotide 3'-phosphatase D 3.1.3.33 polynucleotide 5'-phosphatase D 3.1.3.34 deoxynucleotide 3'-phosphatase D 3.1.3.35 thymidylate 5'-phosphatase D 3.1.3.36 phosphoinositide 5-phosphatase D 3.1.3.37 sedoheptulose-bisphosphatase D 3.1.3.38 3-phosphoglycerate phosphatase D 3.1.3.39 streptomycin-6-phosphatase D 3.1.3.40 guanidinodeoxy-scyllo-inositol-4-phosphatase D 3.1.3.41 4-nitrophenylphosphatase D 3.1.3.42 [glycogen-synthase-D] phosphatase D 3.1.3.43 [pyruvate dehydrogenase (acetyl-transferring)]-phosphatase D 3.1.3.44 [acetyl-CoA carboxylase]-phosphatase D 3.1.3.45 3-deoxy-manno-octulosonate-8-phosphatase E CH54_3015 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family protein K03270 kdsC; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase) [EC:3.1.3.45] D 3.1.3.46 fructose-2,6-bisphosphate 2-phosphatase D 3.1.3.47 [hydroxymethylglutaryl-CoA reductase (NADPH)]-phosphatase D 3.1.3.48 protein-tyrosine-phosphatase D 3.1.3.49 [pyruvate kinase]-phosphatase D 3.1.3.50 sorbitol-6-phosphatase E CH54_3917 HAD hydrolase, IA, variant 1 family protein K19270 hxpA; mannitol-1-/sugar-/sorbitol-6-phosphatase [EC:3.1.3.22 3.1.3.23 3.1.3.50] E CH54_235 HAD hydrolase, IA, variant 1 family protein K24204 hxpB; mannitol-1-/sugar-/sorbitol-6-/2-deoxyglucose-6-phosphatase [EC:3.1.3.22 3.1.3.23 3.1.3.50 3.1.3.68] D 3.1.3.51 dolichyl-phosphatase D 3.1.3.52 [3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)]-phosphatase D 3.1.3.53 [myosin-light-chain] phosphatase D 3.1.3.54 fructose-2,6-bisphosphate 6-phosphatase D 3.1.3.55 caldesmon-phosphatase D 3.1.3.56 inositol-polyphosphate 5-phosphatase D 3.1.3.57 inositol-1,4-bisphosphate 1-phosphatase D 3.1.3.58 sugar-terminal-phosphatase D 3.1.3.59 alkylacetylglycerophosphatase D 3.1.3.60 phosphoenolpyruvate phosphatase D 3.1.3.62 multiple inositol-polyphosphate phosphatase D 3.1.3.63 2-carboxy-D-arabinitol-1-phosphatase D 3.1.3.64 phosphatidylinositol-3-phosphatase D 3.1.3.66 phosphatidylinositol-3,4-bisphosphate 4-phosphatase D 3.1.3.67 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase D 3.1.3.68 2-deoxyglucose-6-phosphatase E CH54_235 HAD hydrolase, IA, variant 1 family protein K24204 hxpB; mannitol-1-/sugar-/sorbitol-6-/2-deoxyglucose-6-phosphatase [EC:3.1.3.22 3.1.3.23 3.1.3.50 3.1.3.68] D 3.1.3.69 glucosylglycerol 3-phosphatase D 3.1.3.70 mannosyl-3-phosphoglycerate phosphatase D 3.1.3.71 2-phosphosulfolactate phosphatase D 3.1.3.72 5-phytase D 3.1.3.73 adenosylcobalamin/alpha-ribazole phosphatase E CH54_918 cobC; alpha-ribazole phosphatase K02226 cobC; alpha-ribazole phosphatase [EC:3.1.3.73] D 3.1.3.74 pyridoxal phosphatase D 3.1.3.75 phosphoethanolamine/phosphocholine phosphatase D 3.1.3.76 lipid-phosphate phosphatase D 3.1.3.77 acireductone synthase E CH54_3575 mtnC; 2,3-diketo-5-methylthio-1-phosphopentane phosphatase K09880 mtnC; enolase-phosphatase E1 [EC:3.1.3.77] D 3.1.3.78 phosphatidylinositol-4,5-bisphosphate 4-phosphatase D 3.1.3.79 mannosylfructose-phosphate phosphatase D 3.1.3.80 2,3-bisphosphoglycerate 3-phosphatase D 3.1.3.82 D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase E CH54_3554 gmhB; D,D-heptose 1,7-bisphosphate phosphatase family protein K03273 gmhB; D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [EC:3.1.3.82 3.1.3.83] D 3.1.3.83 D-glycero-alpha-D-manno-heptose 1,7-bisphosphate 7-phosphatase E CH54_3554 gmhB; D,D-heptose 1,7-bisphosphate phosphatase family protein K03273 gmhB; D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [EC:3.1.3.82 3.1.3.83] D 3.1.3.84 ADP-ribose 1''-phosphate phosphatase D 3.1.3.85 glucosyl-3-phosphoglycerate phosphatase D 3.1.3.86 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase D 3.1.3.87 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase D 3.1.3.88 5''-phosphoribostamycin phosphatase D 3.1.3.89 5'-deoxynucleotidase E CH54_3921 HD domain protein K08722 yfbR; 5'-deoxynucleotidase [EC:3.1.3.89] D 3.1.3.90 maltose 6'-phosphate phosphatase D 3.1.3.91 7-methylguanosine nucleotidase D 3.1.3.92 kanosamine-6-phosphate phosphatase D 3.1.3.93 L-galactose 1-phosphate phosphatase D 3.1.3.94 D-galactose 1-phosphate phosphatase D 3.1.3.95 phosphatidylinositol-3,5-bisphosphate 3-phosphatase D 3.1.3.96 pseudouridine 5'-phosphatase D 3.1.3.97 3',5'-nucleoside bisphosphate phosphatase E CH54_524 PHP domain protein K07053 E3.1.3.97; 3',5'-nucleoside bisphosphate phosphatase [EC:3.1.3.97] D 3.1.3.99 IMP-specific 5'-nucleotidase D 3.1.3.100 thiamine phosphate phosphatase E CH54_2049 rsgA; ribosome small subunit-dependent GTPase A K06949 rsgA; ribosome biogenesis GTPase / thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100] D 3.1.3.101 validoxylamine A 7'-phosphate phosphatase D 3.1.3.102 FMN hydrolase E CH54_2779 HAD hydrolase, IA, variant 1 family protein K20862 yigB; FMN hydrolase / 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase [EC:3.1.3.102 3.1.3.104] D 3.1.3.103 3-deoxy-D-glycero-D-galacto-nonulopyranosonate 9-phosphatase D 3.1.3.104 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase E CH54_2779 HAD hydrolase, IA, variant 1 family protein K20862 yigB; FMN hydrolase / 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase [EC:3.1.3.102 3.1.3.104] D 3.1.3.105 N-acetyl-D-muramate 6-phosphate phosphatase D 3.1.3.106 2-lysophosphatidate phosphatase D 3.1.3.107 amicoumacin phosphatase D 3.1.3.108 nocturnin D 3.1.3.109 ribulose-1,5-bisphosphate 5-phosphatase C 3.1.4 Phosphoric-diester hydrolases D 3.1.4.1 phosphodiesterase I D 3.1.4.2 glycerophosphocholine phosphodiesterase D 3.1.4.3 phospholipase C D 3.1.4.4 phospholipase D D 3.1.4.11 phosphoinositide phospholipase C D 3.1.4.12 sphingomyelin phosphodiesterase D 3.1.4.13 serine-ethanolaminephosphate phosphodiesterase D 3.1.4.14 [acyl-carrier-protein] phosphodiesterase E CH54_3652 hypothetical protein K08682 acpH; acyl carrier protein phosphodiesterase [EC:3.1.4.14] D 3.1.4.16 2',3'-cyclic-nucleotide 2'-phosphodiesterase E CH54_1143 hypothetical protein K01119 cpdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase [EC:3.1.4.16 3.1.3.6] E CH54_2016 cpdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase K01119 cpdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase [EC:3.1.4.16 3.1.3.6] D 3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase E CH54_1160 cAMP phosphodiesterases class-II family protein K01120 cpdP; 3',5'-cyclic-nucleotide phosphodiesterase [EC:3.1.4.17] D 3.1.4.35 3',5'-cyclic-GMP phosphodiesterase D 3.1.4.37 2',3'-cyclic-nucleotide 3'-phosphodiesterase D 3.1.4.38 glycerophosphocholine cholinephosphodiesterase D 3.1.4.39 alkylglycerophosphoethanolamine phosphodiesterase D 3.1.4.40 CMP-N-acylneuraminate phosphodiesterase D 3.1.4.41 sphingomyelin phosphodiesterase D D 3.1.4.42 glycerol-1,2-cyclic-phosphate 2-phosphodiesterase D 3.1.4.43 glycerophosphoinositol inositolphosphodiesterase D 3.1.4.44 glycerophosphoinositol glycerophosphodiesterase D 3.1.4.45 N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase D 3.1.4.46 glycerophosphodiester phosphodiesterase E CH54_2794 glycerophosphoryl diester phosphodiesterase family protein K01126 E3.1.4.46; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46] E CH54_2829 glycerophosphoryl diester phosphodiesterase family protein K01126 E3.1.4.46; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46] D 3.1.4.48 dolichylphosphate-glucose phosphodiesterase D 3.1.4.49 dolichylphosphate-mannose phosphodiesterase D 3.1.4.50 glycosylphosphatidylinositol phospholipase D D 3.1.4.51 glucose-1-phospho-D-mannosylglycoprotein phosphodiesterase D 3.1.4.52 cyclic-guanylate-specific phosphodiesterase E CH54_2588 diguanylate cyclase domain protein K14051 gmr; c-di-GMP phosphodiesterase Gmr [EC:3.1.4.52] E CH54_2397 EAL domain protein K21086 pdeH; c-di-GMP phosphodiesterase [EC:3.1.4.52] E CH54_4114 EAL domain protein K26148 K26148; c-di-GMP phosphodiesterase [EC:3.1.4.52] E CH54_4000 EAL domain protein K26148 K26148; c-di-GMP phosphodiesterase [EC:3.1.4.52] D 3.1.4.53 3',5'-cyclic-AMP phosphodiesterase E CH54_3124 calcineurin-like phosphoesterase family protein K03651 cpdA; 3',5'-cyclic-AMP phosphodiesterase [EC:3.1.4.53] D 3.1.4.54 N-acetylphosphatidylethanolamine-hydrolysing phospholipase D D 3.1.4.55 phosphoribosyl 1,2-cyclic phosphate phosphodiesterase E CH54_1954 phnP; phosphonate metabolism protein PhnP K06167 phnP; phosphoribosyl 1,2-cyclic phosphate phosphodiesterase [EC:3.1.4.55] D 3.1.4.56 7,8-dihydroneopterin 2',3'-cyclic phosphate phosphodiesterase D 3.1.4.57 phosphoribosyl 1,2-cyclic phosphate 1,2-diphosphodiesterase D 3.1.4.58 RNA 2',3'-cyclic 3'-phosphodiesterase E CH54_1726 2'-5' RNA ligase K01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58] D 3.1.4.59 cyclic-di-AMP phosphodiesterase D 3.1.4.60 pApA phosphodiesterase D 3.1.4.61 cyclic 2,3-diphosphoglycerate hydrolase C 3.1.5 Triphosphoric-monoester hydrolases D 3.1.5.1 dGTPase E CH54_1713 dgt; dGTPase family protein K01129 dgt; dGTPase [EC:3.1.5.1] C 3.1.6 Sulfuric-ester hydrolases D 3.1.6.1 arylsulfatase (type I) D 3.1.6.2 steryl-sulfatase D 3.1.6.3 glycosulfatase D 3.1.6.4 N-acetylgalactosamine-6-sulfatase D 3.1.6.6 choline-sulfatase D 3.1.6.7 cellulose-polysulfatase D 3.1.6.8 cerebroside-sulfatase D 3.1.6.9 chondro-4-sulfatase D 3.1.6.10 chondro-6-sulfatase D 3.1.6.11 disulfoglucosamine-6-sulfatase D 3.1.6.12 N-acetylgalactosamine-4-sulfatase D 3.1.6.13 iduronate-2-sulfatase D 3.1.6.14 N-acetylglucosamine-6-sulfatase D 3.1.6.15 N-sulfoglucosamine-3-sulfatase D 3.1.6.16 monomethyl-sulfatase D 3.1.6.17 D-lactate-2-sulfatase D 3.1.6.18 glucuronate-2-sulfatase D 3.1.6.19 (R)-specific secondary-alkylsulfatase (type III) D 3.1.6.20 S-sulfosulfanyl-L-cysteine sulfohydrolase D 3.1.6.21 linear primary-alkylsulfatase D 3.1.6.22 branched primary-alkylsulfatase C 3.1.7 Diphosphoric-monoester hydrolases D 3.1.7.1 prenyl-diphosphatase D 3.1.7.2 guanosine-3',5'-bis(diphosphate) 3'-diphosphatase E CH54_2580 RelA/SpoT family protein K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2] D 3.1.7.3 monoterpenyl-diphosphatase D 3.1.7.5 geranylgeranyl diphosphate diphosphatase D 3.1.7.6 farnesyl diphosphatase D 3.1.7.10 (13E)-labda-7,13-dien-15-ol synthase D 3.1.7.11 geranyl diphosphate diphosphatase D 3.1.7.12 (+)-kolavelool synthase D 3.1.7.13 neryl diphosphate diphosphatase C 3.1.8 Phosphoric-triester hydrolases D 3.1.8.1 aryldialkylphosphatase C 3.1.11 Exodeoxyribonucleases producing 5'-phosphomonoesters D 3.1.11.1 exodeoxyribonuclease I E CH54_971 hypothetical protein K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1] D 3.1.11.2 exodeoxyribonuclease III E CH54_566 xth; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2] D 3.1.11.3 exodeoxyribonuclease (lambda-induced) D 3.1.11.4 exodeoxyribonuclease (phage SP3-induced) D 3.1.11.5 exodeoxyribonuclease V E CH54_3495 recD; exodeoxyribonuclease V, alpha subunit K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5] E CH54_3494 recB; exodeoxyribonuclease V, beta subunit K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5] E CH54_3492 recC; exodeoxyribonuclease V, gamma subunit K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5] D 3.1.11.6 exodeoxyribonuclease VII E CH54_1442 xseA; exodeoxyribonuclease VII, large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6] E CH54_3670 xseB; exodeoxyribonuclease VII, small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6] C 3.1.12 Exodeoxyribonucleases producing 3'-phosphomonoesters D 3.1.12.1 5' to 3' exodeoxyribonuclease (nucleoside 3'-phosphate-forming) C 3.1.13 Exoribonucleases producing 5'-phosphomonoesters D 3.1.13.1 exoribonuclease II E CH54_477 rnb; exoribonuclease II K01147 rnb; exoribonuclease II [EC:3.1.13.1] E CH54_2031 rnr; ribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1] D 3.1.13.2 exoribonuclease H D 3.1.13.3 oligonucleotidase D 3.1.13.4 poly(A)-specific ribonuclease D 3.1.13.5 ribonuclease D E CH54_603 rnd; ribonuclease D K03684 rnd; ribonuclease D [EC:3.1.13.5] C 3.1.14 Exoribonucleases producing 3'-phosphomonoesters D 3.1.14.1 yeast ribonuclease C 3.1.15 Exonucleases that are active with either ribo- or deoxyribonucleic acids and produce 5'-phosphomonoesters D 3.1.15.1 venom exonuclease C 3.1.16 Exonucleases that are active with either ribo- or deoxyribonucleic acids and produce 3'-phosphomonoesters D 3.1.16.1 spleen exonuclease C 3.1.21 Endodeoxyribonucleases producing 5'-phosphomonoesters D 3.1.21.1 deoxyribonuclease I E CH54_3379 endonuclease I family protein K01150 endA; deoxyribonuclease I [EC:3.1.21.1] D 3.1.21.2 deoxyribonuclease IV E CH54_4015 apurinic endonuclease family protein K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2] D 3.1.21.3 type I site-specific deoxyribonuclease E CH54_1921 hypothetical protein K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3] E CH54_1924 hypothetical protein K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3] D 3.1.21.4 type II site-specific deoxyribonuclease D 3.1.21.5 type III site-specific deoxyribonuclease E CH54_1522 type III restriction enzyme, res subunit K01156 res; type III restriction enzyme [EC:3.1.21.5] D 3.1.21.6 CC-preferring endodeoxyribonuclease D 3.1.21.7 deoxyribonuclease V E CH54_2891 endonuclease V family protein K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7] D 3.1.21.8 T4 deoxyribonuclease II D 3.1.21.9 T4 deoxyribonuclease IV D 3.1.21.10 crossover junction endodeoxyribonuclease E CH54_623 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10] E CH54_3802 endodeoxyribonuclease RusA family protein K01160 rusA; crossover junction endodeoxyribonuclease RusA [EC:3.1.21.10] C 3.1.22 Endodeoxyribonucleases producing 3'-phosphomonoesters D 3.1.22.1 deoxyribonuclease II D 3.1.22.2 Aspergillus deoxyribonuclease K1 D 3.1.22.5 deoxyribonuclease X C 3.1.25 Site-specific endodeoxyribonucleases that are specific for altered bases D 3.1.25.1 deoxyribonuclease (pyrimidine dimer) C 3.1.26 Endoribonucleases producing 5'-phosphomonoesters D 3.1.26.1 Physarum polycephalum ribonuclease D 3.1.26.2 ribonuclease alpha D 3.1.26.3 ribonuclease III E CH54_1499 rnc; ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3] D 3.1.26.4 ribonuclease H E CH54_1586 RNase H family protein K03469 rnhA; ribonuclease HI [EC:3.1.26.4] E CH54_3534 ribonuclease HII family protein K03470 rnhB; ribonuclease HII [EC:3.1.26.4] D 3.1.26.5 ribonuclease P E CH54_2498 rnpA; ribonuclease P protein component K03536 rnpA; ribonuclease P protein component [EC:3.1.26.5] D 3.1.26.6 ribonuclease IV D 3.1.26.7 ribonuclease P4 D 3.1.26.8 ribonuclease M5 D 3.1.26.9 ribonuclease [poly-(U)-specific] D 3.1.26.10 ribonuclease IX D 3.1.26.11 tRNase Z D 3.1.26.12 ribonuclease E E CH54_70 ribonuclease, Rne/Rng family domain protein K08300 rne; ribonuclease E [EC:3.1.26.12] D 3.1.26.13 retroviral ribonuclease H C 3.1.27 Endoribonucleases producing 3'-phosphomonoesters D 3.1.27.7 ribonuclease F D 3.1.27.8 ribonuclease V C 3.1.30 Endoribonucleases that are active with either ribo- or deoxyribonucleic acids and produce 5'-phosphomonoesters D 3.1.30.1 Aspergillus nuclease S1 D 3.1.30.2 Serratia marcescens nuclease C 3.1.31 Endoribonucleases that are active with either ribo- or deoxyribonucleic acids and produce 3'-phosphomonoesters D 3.1.31.1 micrococcal nuclease B 3.2 Glycosylases C 3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds D 3.2.1.1 alpha-amylase E CH54_2482 alpha amylase, catalytic domain protein K01176 AMY; alpha-amylase [EC:3.2.1.1] E CH54_733 alpha amylase, catalytic domain protein K01176 AMY; alpha-amylase [EC:3.2.1.1] D 3.2.1.2 beta-amylase D 3.2.1.3 glucan 1,4-alpha-glucosidase D 3.2.1.4 cellulase E CH54_2406 glycosyl hydrolases 8 family protein K20542 bcsZ; endoglucanase [EC:3.2.1.4] D 3.2.1.6 endo-1,3(4)-beta-glucanase D 3.2.1.7 inulinase D 3.2.1.8 endo-1,4-beta-xylanase D 3.2.1.10 oligo-1,6-glucosidase D 3.2.1.11 dextranase D 3.2.1.14 chitinase D 3.2.1.15 endo-polygalacturonase D 3.2.1.17 lysozyme E CH54_3806 phage lysozyme family protein K01185 E3.2.1.17; lysozyme [EC:3.2.1.17] D 3.2.1.18 exo-alpha-sialidase D 3.2.1.20 alpha-glucosidase E CH54_3648 alpha amylase, catalytic domain protein K01187 malZ; alpha-glucosidase [EC:3.2.1.20] E CH54_3446 glycosyl hydrolases 31 family protein K01187 malZ; alpha-glucosidase [EC:3.2.1.20] D 3.2.1.21 beta-glucosidase D 3.2.1.22 alpha-galactosidase D 3.2.1.23 beta-galactosidase E CH54_825 glycosyl hydrolases 2 family protein K01190 lacZ; beta-galactosidase [EC:3.2.1.23] D 3.2.1.24 alpha-mannosidase D 3.2.1.25 beta-mannosidase D 3.2.1.26 beta-fructofuranosidase D 3.2.1.28 alpha,alpha-trehalase D 3.2.1.31 beta-glucuronidase D 3.2.1.32 endo-1,3-beta-xylanase D 3.2.1.33 amylo-alpha-1,6-glucosidase D 3.2.1.35 hyaluronoglucosaminidase D 3.2.1.36 hyaluronoglucuronidase D 3.2.1.37 xylan 1,4-beta-xylosidase D 3.2.1.38 beta-D-fucosidase D 3.2.1.39 glucan endo-1,3-beta-D-glucosidase D 3.2.1.40 alpha-L-rhamnosidase D 3.2.1.41 pullulanase D 3.2.1.42 GDP-glucosidase D 3.2.1.43 beta-L-rhamnosidase D 3.2.1.45 glucosylceramidase D 3.2.1.46 galactosylceramidase D 3.2.1.48 sucrose alpha-glucosidase D 3.2.1.49 alpha-N-acetylgalactosaminidase D 3.2.1.50 alpha-N-acetylglucosaminidase D 3.2.1.51 alpha-L-fucosidase D 3.2.1.52 beta-N-acetylhexosaminidase E CH54_98 hypothetical protein K01207 nagZ; beta-N-acetylhexosaminidase [EC:3.2.1.52] E CH54_3098 hypothetical protein K01207 nagZ; beta-N-acetylhexosaminidase [EC:3.2.1.52] E CH54_1179 glycosyl hydrolase family 20, catalytic domain protein K12373 HEXA_B; hexosaminidase [EC:3.2.1.52] D 3.2.1.53 beta-N-acetylgalactosaminidase D 3.2.1.54 cyclomaltodextrinase D 3.2.1.55 non-reducing end alpha-L-arabinofuranosidase D 3.2.1.56 glucuronosyl-disulfoglucosamine glucuronidase D 3.2.1.57 isopullulanase D 3.2.1.58 glucan 1,3-beta-glucosidase D 3.2.1.59 glucan endo-1,3-alpha-glucosidase D 3.2.1.60 glucan 1,4-alpha-maltotetraohydrolase D 3.2.1.61 mycodextranase D 3.2.1.62 glycosylceramidase D 3.2.1.63 1,2-alpha-L-fucosidase D 3.2.1.64 2,6-beta-fructan 6-levanbiohydrolase D 3.2.1.65 levanase D 3.2.1.67 galacturonan 1,4-alpha-galacturonidase D 3.2.1.68 isoamylase D 3.2.1.70 glucan 1,6-alpha-glucosidase D 3.2.1.71 glucan endo-1,2-beta-glucosidase D 3.2.1.72 xylan 1,3-beta-xylosidase D 3.2.1.73 licheninase D 3.2.1.74 glucan 1,4-beta-glucosidase D 3.2.1.75 glucan endo-1,6-beta-glucosidase D 3.2.1.76 L-iduronidase D 3.2.1.77 mannan 1,2-(1,3)-alpha-mannosidase D 3.2.1.78 mannan endo-1,4-beta-mannosidase D 3.2.1.80 fructan beta-fructosidase D 3.2.1.81 beta-agarase D 3.2.1.82 exo-poly-alpha-digalacturonosidase D 3.2.1.83 kappa-carrageenase D 3.2.1.84 glucan 1,3-alpha-glucosidase D 3.2.1.85 6-phospho-beta-galactosidase D 3.2.1.86 6-phospho-beta-glucosidase E CH54_2291 hypothetical protein K01222 E3.2.1.86A; 6-phospho-beta-glucosidase [EC:3.2.1.86] E CH54_3874 glycosyl hydrolase 1 family protein K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] E CH54_3986 glycosyl hydrolase 1 family protein K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] E CH54_1237 glycosyl hydrolase 1 family protein K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] E CH54_1540 glycosyl hydrolase 1 family protein K01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86] D 3.2.1.87 capsular-polysaccharide endo-1,3-alpha-galactosidase D 3.2.1.88 non-reducing end beta-L-arabinopyranosidase D 3.2.1.89 arabinogalactan endo-beta-1,4-galactanase D 3.2.1.91 cellulose 1,4-beta-cellobiosidase (non-reducing end) D 3.2.1.92 peptidoglycan beta-N-acetylmuramidase D 3.2.1.93 alpha,alpha-phosphotrehalase E CH54_3002 treC; alpha,alpha-phosphotrehalase K01226 treC; trehalose-6-phosphate hydrolase [EC:3.2.1.93] D 3.2.1.94 glucan 1,6-alpha-isomaltosidase D 3.2.1.95 dextran 1,6-alpha-isomaltotriosidase D 3.2.1.96 mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase D 3.2.1.97 endo-alpha-N-acetylgalactosaminidase D 3.2.1.98 glucan 1,4-alpha-maltohexaosidase D 3.2.1.99 arabinan endo-1,5-alpha-L-arabinanase D 3.2.1.100 mannan 1,4-mannobiosidase D 3.2.1.101 mannan endo-1,6-alpha-mannosidase D 3.2.1.102 blood-group-substance endo-1,4-beta-galactosidase D 3.2.1.103 keratan-sulfate endo-1,4-beta-galactosidase D 3.2.1.104 steryl-beta-glucosidase D 3.2.1.105 3alpha(S)-strictosidine beta-glucosidase D 3.2.1.106 mannosyl-oligosaccharide glucosidase D 3.2.1.107 protein-glucosylgalactosylhydroxylysine glucosidase D 3.2.1.108 lactase D 3.2.1.109 endogalactosaminidase D 3.2.1.111 1,3-alpha-L-fucosidase D 3.2.1.112 2-deoxyglucosidase D 3.2.1.113 mannosyl-oligosaccharide 1,2-alpha-mannosidase D 3.2.1.114 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase D 3.2.1.115 branched-dextran exo-1,2-alpha-glucosidase D 3.2.1.116 glucan 1,4-alpha-maltotriohydrolase D 3.2.1.117 amygdalin beta-glucosidase D 3.2.1.118 prunasin beta-glucosidase D 3.2.1.119 vicianin beta-glucosidase D 3.2.1.120 oligoxyloglucan beta-glycosidase D 3.2.1.121 polymannuronate hydrolase D 3.2.1.122 maltose-6'-phosphate glucosidase E CH54_3624 4 glycosyl hydrolase family protein K01232 glvA; maltose-6'-phosphate glucosidase [EC:3.2.1.122] D 3.2.1.123 endoglycosylceramidase D 3.2.1.124 3-deoxy-2-octulosonidase D 3.2.1.125 raucaffricine beta-glucosidase D 3.2.1.126 coniferin beta-glucosidase D 3.2.1.127 1,6-alpha-L-fucosidase D 3.2.1.128 glycyrrhizin hydrolase D 3.2.1.129 endo-alpha-sialidase D 3.2.1.130 glycoprotein endo-alpha-1,2-mannosidase D 3.2.1.131 xylan alpha-1,2-glucuronosidase D 3.2.1.132 chitosanase D 3.2.1.133 glucan 1,4-alpha-maltohydrolase D 3.2.1.135 neopullulanase D 3.2.1.136 glucuronoarabinoxylan endo-1,4-beta-xylanase D 3.2.1.137 mannan exo-1,2-1,6-alpha-mannosidase D 3.2.1.139 alpha-glucuronidase D 3.2.1.140 lacto-N-biosidase D 3.2.1.141 4-alpha-D-{(1->4)-alpha-D-glucano}trehalose trehalohydrolase D 3.2.1.142 limit dextrinase D 3.2.1.143 poly(ADP-ribose) glycohydrolase D 3.2.1.144 3-deoxyoctulosonase D 3.2.1.145 galactan 1,3-beta-galactosidase D 3.2.1.146 beta-galactofuranosidase D 3.2.1.147 thioglucosidase D 3.2.1.149 beta-primeverosidase D 3.2.1.150 oligoxyloglucan reducing-end-specific cellobiohydrolase D 3.2.1.151 xyloglucan-specific endo-beta-1,4-glucanase D 3.2.1.152 mannosylglycoprotein endo-beta-mannosidase D 3.2.1.153 fructan beta-(2,1)-fructosidase D 3.2.1.154 fructan beta-(2,6)-fructosidase D 3.2.1.155 xyloglucan-specific endo-processive beta-1,4-glucanase D 3.2.1.156 oligosaccharide reducing-end xylanase D 3.2.1.157 iota-carrageenase D 3.2.1.158 alpha-agarase D 3.2.1.159 alpha-neoagaro-oligosaccharide hydrolase D 3.2.1.161 beta-apiosyl-beta-glucosidase D 3.2.1.162 lambda-carrageenase D 3.2.1.163 1,6-alpha-D-mannosidase D 3.2.1.164 galactan endo-1,6-beta-galactosidase D 3.2.1.165 exo-1,4-beta-D-glucosaminidase D 3.2.1.166 heparanase D 3.2.1.167 baicalin-beta-D-glucuronidase D 3.2.1.168 hesperidin 6-O-alpha-L-rhamnosyl-beta-D-glucosidase D 3.2.1.169 protein O-GlcNAcase D 3.2.1.170 mannosylglycerate hydrolase D 3.2.1.171 rhamnogalacturonan hydrolase D 3.2.1.172 unsaturated rhamnogalacturonyl hydrolase D 3.2.1.173 rhamnogalacturonan galacturonohydrolase D 3.2.1.174 rhamnogalacturonan rhamnohydrolase D 3.2.1.175 beta-D-glucopyranosyl abscisate beta-glucosidase D 3.2.1.176 cellulose 1,4-beta-cellobiosidase (reducing end) D 3.2.1.177 alpha-D-xyloside xylohydrolase D 3.2.1.178 beta-porphyranase D 3.2.1.179 gellan tetrasaccharide unsaturated glucuronosyl hydrolase D 3.2.1.180 unsaturated chondroitin disaccharide hydrolase D 3.2.1.181 galactan endo-beta-1,3-galactanase D 3.2.1.182 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase D 3.2.1.183 UDP-N-acetylglucosamine 2-epimerase (hydrolysing) D 3.2.1.184 UDP-N,N'-diacetylbacillosamine 2-epimerase (hydrolysing) D 3.2.1.185 non-reducing end beta-L-arabinofuranosidase D 3.2.1.186 protodioscin 26-O-beta-D-glucosidase D 3.2.1.187 (Ara-f)3-Hyp beta-L-arabinobiosidase D 3.2.1.188 avenacosidase D 3.2.1.189 dioscin glycosidase (diosgenin-forming) D 3.2.1.190 dioscin glycosidase (3-O-beta-D-Glc-diosgenin-forming) D 3.2.1.191 ginsenosidase type III D 3.2.1.192 ginsenoside Rb1 beta-glucosidase D 3.2.1.193 ginsenosidase type I D 3.2.1.194 ginsenosidase type IV D 3.2.1.195 20-O-multi-glycoside ginsenosidase D 3.2.1.196 limit dextrin alpha-1,6-maltotetraose-hydrolase E CH54_2346 glgX; glycogen debranching enzyme GlgX K02438 glgX; glycogen debranching enzyme [EC:3.2.1.196] D 3.2.1.197 beta-1,2-mannosidase D 3.2.1.198 alpha-mannan endo-1,2-alpha-mannanase D 3.2.1.199 sulfoquinovosidase D 3.2.1.200 exo-chitinase (non-reducing end) D 3.2.1.201 exo-chitinase (reducing end) D 3.2.1.202 endo-chitodextinase D 3.2.1.203 carboxymethylcellulase D 3.2.1.204 1,3-alpha-isomaltosidase D 3.2.1.205 isomaltose glucohydrolase D 3.2.1.206 oleuropein beta-glucosidase D 3.2.1.207 mannosyl-oligosaccharide alpha-1,3-glucosidase D 3.2.1.208 glucosylglycerate hydrolase D 3.2.1.209 endoplasmic reticulum Man9GlcNAc2 1,2-alpha-mannosidase D 3.2.1.210 endoplasmic reticulum Man8GlcNAc2 1,2-alpha-mannosidase D 3.2.1.211 endo-(1->3)-fucoidanase D 3.2.1.212 endo-(1->4)-fucoidanase D 3.2.1.213 galactan exo-1,6-beta-galactobiohydrolase (non-reducing end) D 3.2.1.214 exo beta-1,2-glucooligosaccharide sophorohydrolase (non-reducing end) D 3.2.1.215 arabinogalactan exo alpha-(1,3)-alpha-D-galactosyl-(1->3)-L-arabinofuranosidase (non-reducing end) D 3.2.1.216 kojibiose hydrolase D 3.2.1.217 exo-acting protein-alpha-N-acetylgalactosaminidase D 3.2.1.218 alpha-3'-ketoglucosidase D 3.2.1.219 palatinase D 3.2.1.220 ipecoside beta-D-glucosidase D 3.2.1.221 MMP endo-(1,4)-3-O-methyl-alpha-D-mannosidase D 3.2.1.222 funoran endo-beta-hydrolase D 3.2.1.223 arabinogalactan exo alpha-(1,3)-beta-L-arabinopyranosyl-(1->3)-L-arabinofuranosidase (non-reducing end) C 3.2.2 Hydrolysing N-glycosyl compounds D 3.2.2.1 purine nucleosidase D 3.2.2.2 inosine nucleosidase D 3.2.2.3 uridine nucleosidase D 3.2.2.4 AMP nucleosidase E CH54_398 amn; AMP nucleosidase K01241 amn; AMP nucleosidase [EC:3.2.2.4] D 3.2.2.5 NAD+ glycohydrolase D 3.2.2.6 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase D 3.2.2.7 adenosine nucleosidase D 3.2.2.8 ribosylpyrimidine nucleosidase D 3.2.2.9 adenosylhomocysteine nucleosidase E CH54_1714 mtnN; MTA/SAH nucleosidase K01243 mtnN; adenosylhomocysteine nucleosidase [EC:3.2.2.9] D 3.2.2.10 pyrimidine-5'-nucleotide nucleosidase E CH54_3510 hypothetical protein K06966 ppnN; pyrimidine/purine-5'-nucleotide nucleosidase [EC:3.2.2.10 3.2.2.-] D 3.2.2.11 beta-aspartyl-N-acetylglucosaminidase D 3.2.2.12 inosinate nucleosidase D 3.2.2.13 1-methyladenosine nucleosidase D 3.2.2.14 NMN nucleosidase D 3.2.2.15 DNA-deoxyinosine glycosylase D 3.2.2.16 methylthioadenosine nucleosidase D 3.2.2.17 deoxyribodipyrimidine endonucleosidase D 3.2.2.19 [protein ADP-ribosylarginine] hydrolase D 3.2.2.20 DNA-3-methyladenine glycosylase I E CH54_2475 tag; DNA-3-methyladenine glycosylase I family protein K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20] D 3.2.2.21 DNA-3-methyladenine glycosylase II E CH54_770 hhH-GPD superbase excision DNA repair family protein K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21] D 3.2.2.22 rRNA N-glycosylase D 3.2.2.23 DNA-formamidopyrimidine glycosylase E CH54_2648 mutM; DNA-formamidopyrimidine glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] D 3.2.2.24 ADP-ribosyl-[dinitrogen reductase] hydrolase D 3.2.2.25 N-methyl nucleosidase D 3.2.2.26 futalosine hydrolase D 3.2.2.27 uracil-DNA glycosylase E CH54_1511 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] D 3.2.2.28 double-stranded uracil-DNA glycosylase D 3.2.2.29 thymine-DNA glycosylase D 3.2.2.30 aminodeoxyfutalosine nucleosidase D 3.2.2.31 adenine glycosylase E CH54_3361 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] B 3.3 Acting on ether bonds C 3.3.2 Ether hydrolases D 3.3.2.1 isochorismatase E CH54_3173 isochorismatase family protein K01252 entB; bifunctional isochorismate lyase / aryl carrier protein [EC:3.3.2.1 6.3.2.14] D 3.3.2.2 lysoplasmalogenase D 3.3.2.4 trans-epoxysuccinate hydrolase D 3.3.2.6 leukotriene-A4 hydrolase D 3.3.2.7 hepoxilin-epoxide hydrolase D 3.3.2.8 limonene-1,2-epoxide hydrolase D 3.3.2.9 microsomal epoxide hydrolase D 3.3.2.10 soluble epoxide hydrolase D 3.3.2.11 cholesterol-5,6-oxide hydrolase D 3.3.2.12 oxepin-CoA hydrolase D 3.3.2.13 chorismatase D 3.3.2.14 2,4-dinitroanisole O-demethylase D 3.3.2.15 trans-2,3-dihydro-3-hydroxyanthranilic acid synthase B 3.4 Acting on peptide bonds (peptidases) C 3.4.11 Aminopeptidases D 3.4.11.1 leucyl aminopeptidase E CH54_1931 hypothetical protein K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1] D 3.4.11.2 membrane alanyl aminopeptidase E CH54_4119 pepN; aminopeptidase N K01256 pepN; aminopeptidase N [EC:3.4.11.2] D 3.4.11.3 cystinyl aminopeptidase D 3.4.11.4 tripeptide aminopeptidase E CH54_109 pepT; peptidase T K01258 pepT; tripeptide aminopeptidase [EC:3.4.11.4] E CH54_3238 pepT; peptidase T K01258 pepT; tripeptide aminopeptidase [EC:3.4.11.4] D 3.4.11.5 prolyl aminopeptidase E CH54_177 pip; prolyl aminopeptidase K01259 pip; proline iminopeptidase [EC:3.4.11.5] D 3.4.11.6 aminopeptidase B D 3.4.11.7 glutamyl aminopeptidase D 3.4.11.9 Xaa-Pro aminopeptidase E CH54_3403 hypothetical protein K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9] D 3.4.11.10 bacterial leucyl aminopeptidase D 3.4.11.13 clostridial aminopeptidase D 3.4.11.14 cytosol alanyl aminopeptidase D 3.4.11.15 aminopeptidase Y D 3.4.11.16 Xaa-Trp aminopeptidase D 3.4.11.17 tryptophanyl aminopeptidase D 3.4.11.18 methionyl aminopeptidase E CH54_3250 map; methionine aminopeptidase, type I K01265 map; methionyl aminopeptidase [EC:3.4.11.18] E CH54_3519 map; methionine aminopeptidase, type I K01265 map; methionyl aminopeptidase [EC:3.4.11.18] D 3.4.11.19 D-stereospecific aminopeptidase D 3.4.11.20 aminopeptidase Ey D 3.4.11.21 aspartyl aminopeptidase D 3.4.11.22 aminopeptidase I D 3.4.11.23 PepB aminopeptidase E CH54_1459 peptidase family protein K07751 pepB; PepB aminopeptidase [EC:3.4.11.23] D 3.4.11.24 aminopeptidase S D 3.4.11.25 beta-peptidyl aminopeptidase D 3.4.11.26 intermediate cleaving peptidase 55 D 3.4.11.27 archaeal arginyl aminopeptidase C 3.4.13 Dipeptidases D 3.4.13.4 Xaa-Arg dipeptidase D 3.4.13.5 Xaa-methyl-His dipeptidase D 3.4.13.7 Glu-Glu dipeptidase D 3.4.13.9 Xaa-Pro dipeptidase E CH54_2854 metallopeptidase M24 family protein K01271 pepQ; Xaa-Pro dipeptidase [EC:3.4.13.9] D 3.4.13.12 Met-Xaa dipeptidase D 3.4.13.17 non-stereospecific dipeptidase D 3.4.13.18 cytosol nonspecific dipeptidase D 3.4.13.19 membrane dipeptidase D 3.4.13.20 beta-Ala-His dipeptidase D 3.4.13.21 dipeptidase E D 3.4.13.22 D-Ala-D-Ala dipeptidase D 3.4.13.23 cysteinylglycine-S-conjugate dipeptidase C 3.4.14 Dipeptidyl-peptidases and tripeptidyl-peptidases D 3.4.14.1 dipeptidyl-peptidase I D 3.4.14.2 dipeptidyl-peptidase II D 3.4.14.4 dipeptidyl-peptidase III D 3.4.14.5 dipeptidyl-peptidase IV D 3.4.14.6 dipeptidyl-dipeptidase D 3.4.14.9 tripeptidyl-peptidase I D 3.4.14.10 tripeptidyl-peptidase II D 3.4.14.11 Xaa-Pro dipeptidyl-peptidase D 3.4.14.12 Xaa-Xaa-Pro tripeptidyl-peptidase D 3.4.14.13 gamma-D-glutamyl-L-lysine dipeptidyl-peptidase D 3.4.14.14 [mycofactocin precursor peptide] peptidase C 3.4.15 Peptidyl-dipeptidases D 3.4.15.1 peptidyl-dipeptidase A D 3.4.15.4 peptidyl-dipeptidase B D 3.4.15.5 peptidyl-dipeptidase Dcp D 3.4.15.6 cyanophycinase C 3.4.16 Serine-type carboxypeptidases D 3.4.16.2 lysosomal Pro-Xaa carboxypeptidase D 3.4.16.4 serine-type D-Ala-D-Ala carboxypeptidase E CH54_154 penicillin binding transpeptidase domain protein K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4] E CH54_1785 penicillin binding transpeptidase domain protein K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4] E CH54_1724 mrcB; penicillin-binding protein 1B K05365 mrcB; penicillin-binding protein 1B [EC:2.4.99.28 3.4.16.4] E CH54_2312 penicillin-binding, 1A family protein K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] E CH54_1214 mrdA; penicillin-binding protein 2 K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4] E CH54_4035 D-alanyl-D-alanine carboxypeptidase family protein K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] E CH54_1217 D-alanyl-D-alanine carboxypeptidase family protein K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] E CH54_1990 dacB; D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase K07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-] E CH54_3977 beta-lactamase family protein K18988 ampH; serine-type D-Ala-D-Ala carboxypeptidase/endopeptidase [EC:3.4.16.4 3.4.21.-] D 3.4.16.5 carboxypeptidase C D 3.4.16.6 carboxypeptidase D C 3.4.17 Metallocarboxypeptidases D 3.4.17.1 carboxypeptidase A D 3.4.17.2 carboxypeptidase B D 3.4.17.3 lysine carboxypeptidase D 3.4.17.4 Gly-Xaa carboxypeptidase D 3.4.17.6 alanine carboxypeptidase D 3.4.17.8 muramoylpentapeptide carboxypeptidase D 3.4.17.10 carboxypeptidase E D 3.4.17.11 glutamate carboxypeptidase D 3.4.17.12 carboxypeptidase M D 3.4.17.13 muramoyltetrapeptide carboxypeptidase E CH54_4001 nlpC/P60 family protein K13694 mepS; murein DD-endopeptidase / murein LD-carboxypeptidase [EC:3.4.-.- 3.4.17.13] D 3.4.17.14 zinc D-Ala-D-Ala carboxypeptidase D 3.4.17.15 carboxypeptidase A2 D 3.4.17.16 membrane Pro-Xaa carboxypeptidase D 3.4.17.17 tubulinyl-Tyr carboxypeptidase D 3.4.17.18 carboxypeptidase T D 3.4.17.19 carboxypeptidase Taq E CH54_371 carboxypeptidase Taq (M32) metallopeptidase family protein K01299 E3.4.17.19; carboxypeptidase Taq [EC:3.4.17.19] D 3.4.17.20 carboxypeptidase U D 3.4.17.21 glutamate carboxypeptidase II D 3.4.17.22 metallocarboxypeptidase D D 3.4.17.23 angiotensin-converting enzyme 2 D 3.4.17.24 tubulin-glutamate carboxypeptidase D 3.4.17.25 glutathione-S-conjugate glycine hydrolase C 3.4.18 Cysteine-type carboxypeptidases D 3.4.18.1 cathepsin X C 3.4.19 Omega peptidases D 3.4.19.1 acylaminoacyl-peptidase D 3.4.19.2 peptidyl-glycinamidase D 3.4.19.3 pyroglutamyl-peptidase I E CH54_1153 pcp; pyroglutamyl-peptidase I K01304 pcp; pyroglutamyl-peptidase [EC:3.4.19.3] D 3.4.19.5 beta-aspartyl-peptidase D 3.4.19.6 pyroglutamyl-peptidase II D 3.4.19.7 N-formylmethionyl-peptidase D 3.4.19.9 folate gamma-glutamyl hydrolase D 3.4.19.11 gamma-D-glutamyl-meso-diaminopimelate peptidase D 3.4.19.12 ubiquitinyl hydrolase 1 D 3.4.19.13 glutathione gamma-glutamate hydrolase E CH54_3650 ggt; gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] D 3.4.19.14 leukotriene-C4 hydrolase D 3.4.19.15 desampylase D 3.4.19.16 glucosinolate gamma-glutamyl hydrolase C 3.4.21 Serine endopeptidases D 3.4.21.1 chymotrypsin D 3.4.21.2 chymotrypsin C D 3.4.21.3 metridin D 3.4.21.4 trypsin D 3.4.21.5 thrombin D 3.4.21.6 coagulation factor Xa D 3.4.21.7 plasmin D 3.4.21.9 enteropeptidase D 3.4.21.10 acrosin D 3.4.21.12 alpha-lytic endopeptidase D 3.4.21.19 glutamyl endopeptidase D 3.4.21.20 cathepsin G D 3.4.21.21 coagulation factor VIIa D 3.4.21.22 coagulation factor IXa D 3.4.21.25 cucumisin D 3.4.21.26 prolyl oligopeptidase D 3.4.21.27 coagulation factor XIa D 3.4.21.32 brachyurin D 3.4.21.34 plasma kallikrein D 3.4.21.35 tissue kallikrein D 3.4.21.36 pancreatic elastase D 3.4.21.37 leukocyte elastase D 3.4.21.38 coagulation factor XIIa D 3.4.21.39 chymase D 3.4.21.41 complement subcomponent C_overbar_1r_ D 3.4.21.42 complement subcomponent C_overbar_1s_ D 3.4.21.43 classical-complement-pathway C3/C5 convertase D 3.4.21.45 complement factor I D 3.4.21.46 complement factor D D 3.4.21.47 alternative-complement-pathway C3/C5 convertase D 3.4.21.48 cerevisin D 3.4.21.49 hypodermin C D 3.4.21.50 lysyl endopeptidase D 3.4.21.53 endopeptidase La E CH54_3688 lon; endopeptidase La K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53] D 3.4.21.54 gamma-renin D 3.4.21.55 venombin AB D 3.4.21.57 leucyl endopeptidase D 3.4.21.59 tryptase D 3.4.21.60 scutelarin D 3.4.21.61 kexin D 3.4.21.62 subtilisin D 3.4.21.63 oryzin D 3.4.21.64 peptidase K D 3.4.21.65 thermomycolin D 3.4.21.66 thermitase D 3.4.21.67 endopeptidase So D 3.4.21.68 t-plasminogen activator D 3.4.21.69 protein C (activated) D 3.4.21.70 pancreatic endopeptidase E D 3.4.21.71 pancreatic elastase II D 3.4.21.72 IgA-specific serine endopeptidase D 3.4.21.73 u-plasminogen activator D 3.4.21.74 venombin A D 3.4.21.75 furin D 3.4.21.76 myeloblastin D 3.4.21.77 semenogelase D 3.4.21.78 granzyme A D 3.4.21.79 granzyme B D 3.4.21.80 streptogrisin A D 3.4.21.81 streptogrisin B D 3.4.21.82 glutamyl endopeptidase II D 3.4.21.83 oligopeptidase B E CH54_175 prolyl oligopeptidase family protein K01354 ptrB; oligopeptidase B [EC:3.4.21.83] D 3.4.21.84 limulus clotting factor _overbar_C_ D 3.4.21.85 limulus clotting factor _overbar_B_ D 3.4.21.86 limulus clotting enzyme D 3.4.21.88 repressor LexA E CH54_2928 lexA; repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88] D 3.4.21.89 signal peptidase I E CH54_1500 lepB; signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] D 3.4.21.90 togavirin D 3.4.21.91 flavivirin D 3.4.21.92 endopeptidase Clp E CH54_3686 clpP; ATP-dependent Clp endopeptidase, proteolytic subunit ClpP K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] D 3.4.21.93 proprotein convertase 1 D 3.4.21.94 proprotein convertase 2 D 3.4.21.95 snake venom factor V activator D 3.4.21.96 lactocepin D 3.4.21.97 assemblin D 3.4.21.98 hepacivirin D 3.4.21.99 spermosin D 3.4.21.100 sedolisin D 3.4.21.101 xanthomonalisin D 3.4.21.102 C-terminal processing peptidase E CH54_217 hypothetical protein K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102] D 3.4.21.103 physarolisin D 3.4.21.104 mannan-binding lectin-associated serine protease-2 D 3.4.21.105 rhomboid protease E CH54_2338 glpG; rhomboid family protease GlpG K02441 glpG; rhomboid protease GlpG [EC:3.4.21.105] D 3.4.21.106 hepsin D 3.4.21.107 peptidase Do E CH54_1712 peptidase Do family protein K04771 degP; serine protease Do [EC:3.4.21.107] D 3.4.21.108 HtrA2 peptidase D 3.4.21.109 matriptase D 3.4.21.110 C5a peptidase D 3.4.21.111 aqualysin 1 D 3.4.21.112 site-1 protease D 3.4.21.113 pestivirus NS3 polyprotein peptidase D 3.4.21.114 equine arterivirus serine peptidase D 3.4.21.115 infectious pancreatic necrosis birnavirus Vp4 peptidase D 3.4.21.116 SpoIVB peptidase D 3.4.21.117 stratum corneum chymotryptic enzyme D 3.4.21.118 kallikrein 8 D 3.4.21.119 kallikrein 13 D 3.4.21.120 oviductin D 3.4.21.121 Lys-Lys/Arg-Xaa endopeptidase D 3.4.21.122 transmembrane protease serine 2 D 3.4.21.123 kumamolysin C 3.4.22 Cysteine endopeptidases D 3.4.22.1 cathepsin B D 3.4.22.2 papain D 3.4.22.3 ficain D 3.4.22.6 chymopapain D 3.4.22.7 asclepain D 3.4.22.8 clostripain D 3.4.22.10 streptopain D 3.4.22.14 actinidain D 3.4.22.15 cathepsin L D 3.4.22.16 cathepsin H D 3.4.22.24 cathepsin T D 3.4.22.25 glycyl endopeptidase D 3.4.22.26 cancer procoagulant D 3.4.22.27 cathepsin S D 3.4.22.28 picornain 3C D 3.4.22.29 picornain 2A D 3.4.22.30 caricain D 3.4.22.31 ananain D 3.4.22.32 stem bromelain D 3.4.22.33 fruit bromelain D 3.4.22.34 legumain D 3.4.22.35 histolysain D 3.4.22.36 caspase-1 D 3.4.22.37 gingipain R D 3.4.22.38 cathepsin K D 3.4.22.39 adenain D 3.4.22.40 bleomycin hydrolase D 3.4.22.41 cathepsin F D 3.4.22.42 cathepsin O D 3.4.22.43 cathepsin V D 3.4.22.44 nuclear-inclusion-a endopeptidase D 3.4.22.45 helper-component proteinase D 3.4.22.46 L-peptidase D 3.4.22.47 gingipain K D 3.4.22.48 staphopain D 3.4.22.49 separase D 3.4.22.50 V-cath endopeptidase D 3.4.22.51 cruzipain D 3.4.22.52 calpain-1 D 3.4.22.53 calpain-2 D 3.4.22.54 calpain-3 D 3.4.22.55 caspase-2 D 3.4.22.56 caspase-3 D 3.4.22.57 caspase-4 D 3.4.22.58 caspase-5 D 3.4.22.59 caspase-6 D 3.4.22.60 caspase-7 D 3.4.22.61 caspase-8 D 3.4.22.62 caspase-9 D 3.4.22.63 caspase-10 D 3.4.22.64 caspase-11 D 3.4.22.65 peptidase 1 (mite) D 3.4.22.66 calicivirin D 3.4.22.67 zingipain D 3.4.22.68 Ulp1 peptidase D 3.4.22.69 SARS coronavirus main proteinase D 3.4.22.70 sortase A D 3.4.22.71 sortase B C 3.4.23 Aspartic endopeptidases D 3.4.23.1 pepsin A D 3.4.23.2 pepsin B D 3.4.23.3 gastricsin D 3.4.23.4 chymosin D 3.4.23.5 cathepsin D D 3.4.23.12 nepenthesin D 3.4.23.15 renin D 3.4.23.16 HIV-1 retropepsin D 3.4.23.17 pro-opiomelanocortin converting enzyme D 3.4.23.18 aspergillopepsin I D 3.4.23.19 aspergillopepsin II D 3.4.23.20 penicillopepsin D 3.4.23.21 rhizopuspepsin D 3.4.23.22 endothiapepsin D 3.4.23.23 mucorpepsin D 3.4.23.24 candidapepsin D 3.4.23.25 saccharopepsin D 3.4.23.26 rhodotorulapepsin D 3.4.23.28 acrocylindropepsin D 3.4.23.29 polyporopepsin D 3.4.23.30 pycnoporopepsin D 3.4.23.31 scytalidopepsin A D 3.4.23.32 scytalidopepsin B D 3.4.23.34 cathepsin E D 3.4.23.35 barrierpepsin D 3.4.23.36 signal peptidase II E CH54_1831 lspA; signal peptidase II K03101 lspA; signal peptidase II [EC:3.4.23.36] D 3.4.23.38 plasmepsin I D 3.4.23.39 plasmepsin II D 3.4.23.40 phytepsin D 3.4.23.41 yapsin 1 D 3.4.23.42 thermopsin D 3.4.23.43 prepilin peptidase E CH54_3152 type IV leader peptidase family protein K02278 cpaA; prepilin peptidase CpaA [EC:3.4.23.43] E CH54_3466 type IV leader peptidase family protein K02464 gspO; general secretion pathway protein O [EC:3.4.23.43 2.1.1.-] D 3.4.23.44 nodavirus endopeptidase D 3.4.23.45 memapsin 1 D 3.4.23.46 memapsin 2 D 3.4.23.47 HIV-2 retropepsin D 3.4.23.48 plasminogen activator Pla E CH54_3981 omptin family protein K08566 pla; plasminogen activator [EC:3.4.23.48] D 3.4.23.49 omptin D 3.4.23.50 human endogenous retrovirus K endopeptidase D 3.4.23.51 HycI peptidase E CH54_1018 hycI; hydrogenase maturation peptidase HycI K08315 hycI; hydrogenase 3 maturation protease [EC:3.4.23.51] D 3.4.23.52 preflagellin peptidase C 3.4.24 Metalloendopeptidases D 3.4.24.1 atrolysin A D 3.4.24.3 microbial collagenase D 3.4.24.6 leucolysin D 3.4.24.7 interstitial collagenase D 3.4.24.11 neprilysin D 3.4.24.12 envelysin D 3.4.24.13 IgA-specific metalloendopeptidase D 3.4.24.14 procollagen N-endopeptidase D 3.4.24.15 thimet oligopeptidase D 3.4.24.16 neurolysin D 3.4.24.17 stromelysin 1 D 3.4.24.18 meprin A D 3.4.24.19 procollagen C-endopeptidase D 3.4.24.20 peptidyl-Lys metalloendopeptidase D 3.4.24.21 astacin D 3.4.24.22 stromelysin 2 D 3.4.24.23 matrilysin D 3.4.24.24 gelatinase A D 3.4.24.25 vibriolysin D 3.4.24.26 pseudolysin D 3.4.24.27 thermolysin D 3.4.24.28 bacillolysin D 3.4.24.29 aureolysin D 3.4.24.30 coccolysin D 3.4.24.31 mycolysin D 3.4.24.32 beta-lytic metalloendopeptidase D 3.4.24.33 peptidyl-Asp metalloendopeptidase D 3.4.24.34 neutrophil collagenase D 3.4.24.35 gelatinase B D 3.4.24.36 leishmanolysin D 3.4.24.37 saccharolysin D 3.4.24.38 gametolysin D 3.4.24.39 deuterolysin D 3.4.24.40 serralysin E CH54_2388 hypothetical protein K01406 prtC; serralysin [EC:3.4.24.40] D 3.4.24.41 atrolysin B D 3.4.24.42 atrolysin C D 3.4.24.43 atroxase D 3.4.24.44 atrolysin E D 3.4.24.45 atrolysin F D 3.4.24.46 adamalysin D 3.4.24.47 horrilysin D 3.4.24.48 ruberlysin D 3.4.24.49 bothropasin D 3.4.24.50 bothrolysin D 3.4.24.51 ophiolysin D 3.4.24.52 trimerelysin I D 3.4.24.53 trimerelysin II D 3.4.24.54 mucrolysin D 3.4.24.55 pitrilysin E CH54_3493 insulinase family protein K01407 ptrA; protease III [EC:3.4.24.55] D 3.4.24.56 insulysin D 3.4.24.57 O-sialoglycoprotein endopeptidase D 3.4.24.58 russellysin D 3.4.24.59 mitochondrial intermediate peptidase D 3.4.24.60 dactylysin D 3.4.24.61 nardilysin D 3.4.24.62 magnolysin D 3.4.24.63 meprin B D 3.4.24.64 mitochondrial processing peptidase D 3.4.24.65 macrophage elastase D 3.4.24.66 choriolysin L D 3.4.24.67 choriolysin H D 3.4.24.68 tentoxilysin D 3.4.24.69 bontoxilysin D 3.4.24.70 oligopeptidase A E CH54_2390 peptidase M3 family protein K01414 prlC; oligopeptidase A [EC:3.4.24.70] D 3.4.24.71 endothelin-converting enzyme 1 D 3.4.24.72 fibrolase D 3.4.24.73 jararhagin D 3.4.24.74 fragilysin D 3.4.24.75 lysostaphin D 3.4.24.76 flavastacin D 3.4.24.77 snapalysin D 3.4.24.78 gpr endopeptidase D 3.4.24.79 pappalysin-1 D 3.4.24.80 membrane-type matrix metalloproteinase-1 D 3.4.24.81 ADAM10 endopeptidase D 3.4.24.82 ADAMTS-4 endopeptidase D 3.4.24.83 anthrax lethal factor endopeptidase D 3.4.24.84 Ste24 endopeptidase D 3.4.24.85 S2P endopeptidase D 3.4.24.86 ADAM 17 endopeptidase D 3.4.24.87 ADAMTS13 endopeptidase D 3.4.24.89 Pro-Pro endopeptidase C 3.4.25 Threonine endopeptidases D 3.4.25.1 proteasome endopeptidase complex D 3.4.25.2 HslU---HslV peptidase E CH54_2686 hslV; ATP-dependent protease HslVU, peptidase subunit K01419 hslV; ATP-dependent HslUV protease, peptidase subunit HslV [EC:3.4.25.2] C 3.4.26 Glutamic endopeptidases D 3.4.26.1 intramembrane prenyl-peptidase Rce1 D 3.4.26.2 scytalidoglutamic peptidase B 3.5 Acting on carbon-nitrogen bonds, other than peptide bonds C 3.5.1 In linear amides D 3.5.1.1 asparaginase E CH54_4090 L-asparaginase, type II family protein K01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1] E CH54_573 L-asparaginase, type I family protein K01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1] D 3.5.1.2 glutaminase E CH54_3364 glsA; glutaminase A K01425 glsA; glutaminase [EC:3.5.1.2] E CH54_713 glsA; glutaminase A K01425 glsA; glutaminase [EC:3.5.1.2] E CH54_3094 glsA; glutaminase A K01425 glsA; glutaminase [EC:3.5.1.2] D 3.5.1.3 omega-amidase E CH54_3572 carbon-nitrogen hydrolase family protein K13566 NIT2; omega-amidase [EC:3.5.1.3] D 3.5.1.4 amidase E CH54_1642 acetamidase/Formamidase family protein K01426 E3.5.1.4; amidase [EC:3.5.1.4] D 3.5.1.5 urease E CH54_1555 ureC; urease, alpha subunit K01428 ureC; urease subunit alpha [EC:3.5.1.5] E CH54_1556 ureB; urease, beta subunit K01429 ureB; urease subunit beta [EC:3.5.1.5] E CH54_1557 ureA; urease, gamma subunit K01430 ureA; urease subunit gamma [EC:3.5.1.5] D 3.5.1.6 beta-ureidopropionase D 3.5.1.7 ureidosuccinase D 3.5.1.8 formylaspartate deformylase D 3.5.1.9 arylformamidase D 3.5.1.10 formyltetrahydrofolate deformylase E CH54_561 purU; formyltetrahydrofolate deformylase K01433 purU; formyltetrahydrofolate deformylase [EC:3.5.1.10] D 3.5.1.11 penicillin amidase E CH54_711 penicillin amidase family protein K01434 pac; penicillin G amidase [EC:3.5.1.11] D 3.5.1.12 biotinidase D 3.5.1.13 aryl-acylamidase D 3.5.1.14 N-acyl-aliphatic-L-amino acid amidohydrolase D 3.5.1.15 aspartoacylase D 3.5.1.16 acetylornithine deacetylase E CH54_2696 argE; acetylornithine deacetylase K01438 argE; acetylornithine deacetylase [EC:3.5.1.16] D 3.5.1.17 acyl-lysine deacylase D 3.5.1.18 succinyl-diaminopimelate desuccinylase E CH54_1336 dapE; succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] D 3.5.1.19 nicotinamidase E CH54_574 isochorismatase family protein K08281 pncA; nicotinamidase/pyrazinamidase [EC:3.5.1.19 3.5.1.-] D 3.5.1.20 citrullinase D 3.5.1.21 N-acetyl-beta-alanine deacetylase D 3.5.1.22 pantothenase D 3.5.1.23 ceramidase D 3.5.1.24 choloylglycine hydrolase D 3.5.1.25 N-acetylglucosamine-6-phosphate deacetylase E CH54_1185 nagA; N-acetylglucosamine-6-phosphate deacetylase K01443 nagA; N-acetylglucosamine-6-phosphate deacetylase [EC:3.5.1.25] D 3.5.1.26 N4-(beta-N-acetylglucosaminyl)-L-asparaginase D 3.5.1.28 N-acetylmuramoyl-L-alanine amidase E CH54_394 N-acetylmuramoyl-L-alanine amidase family protein K01447 xlyAB; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] E CH54_3497 N-acetylmuramoyl-L-alanine amidase family protein K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] E CH54_2041 N-acetylmuramoyl-L-alanine amidase family protein K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] E CH54_1760 N-acetylmuramoyl-L-alanine amidase family protein K03806 ampD; N-acetyl-anhydromuramoyl-L-alanine amidase [EC:3.5.1.28] E CH54_223 N-acetylmuramoyl-L-alanine amidase family protein K11066 amiD; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] D 3.5.1.29 2-(acetamidomethylene)succinate hydrolase D 3.5.1.30 5-aminopentanamidase D 3.5.1.31 formylmethionine deformylase D 3.5.1.32 hippurate hydrolase D 3.5.1.33 N-acetylglucosamine deacetylase D 3.5.1.35 D-glutaminase D 3.5.1.36 N-methyl-2-oxoglutaramate hydrolase D 3.5.1.38 glutamin-(asparagin-)ase D 3.5.1.39 alkylamidase D 3.5.1.40 acylagmatine amidase D 3.5.1.41 chitin deacetylase D 3.5.1.42 nicotinamide-nucleotide amidase E CH54_3959 molybdenum cofactor synthesis domain protein K03742 pncC; nicotinamide-nucleotide amidase [EC:3.5.1.42] E CH54_1630 amidohydrolase, PncC family domain protein K03743 pncC; nicotinamide-nucleotide amidase [EC:3.5.1.42] D 3.5.1.43 peptidyl-glutaminase D 3.5.1.44 protein-glutamine glutaminase E CH54_807 cheB methylesterase family protein K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44] D 3.5.1.46 6-aminohexanoate-oligomer exohydrolase D 3.5.1.47 N-acetyldiaminopimelate deacetylase D 3.5.1.48 acetylspermidine deacetylase D 3.5.1.49 formamidase D 3.5.1.50 pentanamidase D 3.5.1.51 4-acetamidobutyryl-CoA deacetylase D 3.5.1.52 peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase D 3.5.1.53 N-carbamoylputrescine amidase E CH54_3374 aguB; N-carbamoylputrescine amidase K12251 aguB; N-carbamoylputrescine amidase [EC:3.5.1.53] D 3.5.1.54 allophanate hydrolase D 3.5.1.55 long-chain-fatty-acyl-glutamate deacylase D 3.5.1.56 N,N-dimethylformamidase D 3.5.1.57 tryptophanamidase D 3.5.1.58 N-benzyloxycarbonylglycine hydrolase D 3.5.1.59 N-carbamoylsarcosine amidase D 3.5.1.60 N-(long-chain-acyl)ethanolamine deacylase D 3.5.1.62 acetylputrescine deacetylase D 3.5.1.63 4-acetamidobutyrate deacetylase D 3.5.1.64 Nalpha-benzyloxycarbonylleucine hydrolase D 3.5.1.65 theanine hydrolase D 3.5.1.66 2-(hydroxymethyl)-3-(acetamidomethylene)succinate hydrolase D 3.5.1.67 4-methyleneglutaminase D 3.5.1.68 N-formylglutamate deformylase E CH54_675 hutG; N-formylglutamate deformylase K01458 hutG; N-formylglutamate deformylase [EC:3.5.1.68] D 3.5.1.69 glycosphingolipid deacylase D 3.5.1.70 aculeacin-A deacylase D 3.5.1.71 N-feruloylglycine deacylase D 3.5.1.72 D-benzoylarginine-4-nitroanilide amidase D 3.5.1.73 carnitinamidase D 3.5.1.74 chenodeoxycholoyltaurine hydrolase D 3.5.1.75 urethanase D 3.5.1.76 arylalkyl acylamidase D 3.5.1.77 N-carbamoyl-D-amino-acid hydrolase D 3.5.1.78 glutathionylspermidine amidase D 3.5.1.79 phthalyl amidase D 3.5.1.81 N-acyl-D-amino-acid deacylase D 3.5.1.82 N-acyl-D-glutamate deacylase D 3.5.1.83 N-acyl-D-aspartate deacylase D 3.5.1.84 biuret amidohydrolase D 3.5.1.85 (S)-N-acetyl-1-phenylethylamine hydrolase D 3.5.1.86 mandelamide amidase D 3.5.1.87 N-carbamoyl-L-amino-acid hydrolase D 3.5.1.88 peptide deformylase E CH54_2219 def; peptide deformylase K01462 PDF; peptide deformylase [EC:3.5.1.88] D 3.5.1.89 N-acetylglucosaminylphosphatidylinositol deacetylase D 3.5.1.90 adenosylcobinamide hydrolase D 3.5.1.91 N-substituted formamide deformylase D 3.5.1.92 pantetheine hydrolase D 3.5.1.93 glutaryl-7-aminocephalosporanic-acid acylase D 3.5.1.94 gamma-glutamyl-gamma-aminobutyrate hydrolase D 3.5.1.95 N-malonylurea hydrolase D 3.5.1.96 succinylglutamate desuccinylase E CH54_677 astE; succinylglutamate desuccinylase K05526 astE; succinylglutamate desuccinylase [EC:3.5.1.96] D 3.5.1.97 acyl-homoserine-lactone acylase D 3.5.1.98 histone deacetylase D 3.5.1.99 fatty acid amide hydrolase D 3.5.1.100 (R)-amidase D 3.5.1.101 L-proline amide hydrolase D 3.5.1.102 2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5'-monophosphate deformylase D 3.5.1.103 N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase D 3.5.1.104 peptidoglycan-N-acetylglucosamine deacetylase D 3.5.1.105 chitin disaccharide deacetylase E CH54_1537 ydjC-like family protein K03478 chbG; chitin disaccharide deacetylase [EC:3.5.1.105] D 3.5.1.106 N-formylmaleamate deformylase D 3.5.1.107 maleamate amidohydrolase D 3.5.1.108 UDP-3-O-acyl-N-acetylglucosamine deacetylase E CH54_1773 lpxC; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase K02535 lpxC; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [EC:3.5.1.108] D 3.5.1.109 sphingomyelin deacylase D 3.5.1.110 ureidoacrylate amidohydrolase D 3.5.1.111 2-oxoglutaramate amidase D 3.5.1.112 2'-N-acetylparomamine deacetylase D 3.5.1.113 2'''-acetyl-6'''-hydroxyneomycin C deacetylase D 3.5.1.114 N-acyl-aromatic-L-amino acid amidohydrolase D 3.5.1.115 mycothiol S-conjugate amidase D 3.5.1.116 ureidoglycolate amidohydrolase D 3.5.1.117 6-aminohexanoate-oligomer endohydrolase D 3.5.1.118 gamma-glutamyl hercynylcysteine S-oxide hydrolase D 3.5.1.119 Pup amidohydrolase D 3.5.1.121 protein N-terminal asparagine amidohydrolase D 3.5.1.122 protein N-terminal glutamine amidohydrolase D 3.5.1.123 gamma-glutamylanilide hydrolase D 3.5.1.124 protein deglycase E CH54_3672 DJ-1 family protein K03152 thiJ; protein deglycase [EC:3.5.1.124] D 3.5.1.125 N2-acetyl-L-2,4-diaminobutanoate deacetylase D 3.5.1.126 oxamate amidohydrolase D 3.5.1.127 jasmonoyl-L-amino acid hydrolase D 3.5.1.128 deaminated glutathione amidase D 3.5.1.129 N5-(cytidine 5'-diphosphoramidyl)-L-glutamine hydrolase D 3.5.1.130 [amino group carrier protein]-lysine hydrolase D 3.5.1.131 1-carboxybiuret hydrolase D 3.5.1.132 [amino group carrier protein]-ornithine hydrolase D 3.5.1.133 Nalpha-acyl-L-glutamine aminoacylase D 3.5.1.134 (indol-3-yl)acetyl-L-aspartate hydrolase D 3.5.1.135 N4-acetylcytidine amidohydrolase E CH54_173 ASCH domain protein K09900 E3.5.1.135; N4-acetylcytidine amidohydrolase [EC:3.5.1.135] D 3.5.1.136 N,N'-diacetylchitobiose non-reducing end deacetylase D 3.5.1.137 N-methylcarbamate hydrolase D 3.5.1.138 lipoamidase C 3.5.2 In cyclic amides D 3.5.2.1 barbiturase D 3.5.2.2 dihydropyrimidinase D 3.5.2.3 dihydroorotase E CH54_68 pyrC; dihydroorotase, homodimeric type K01465 URA4; dihydroorotase [EC:3.5.2.3] E CH54_2994 amidohydrolase family protein K01465 URA4; dihydroorotase [EC:3.5.2.3] D 3.5.2.4 carboxymethylhydantoinase D 3.5.2.5 allantoinase D 3.5.2.6 beta-lactamase E CH54_188 beta-lactamase family protein K01467 ampC; beta-lactamase class C [EC:3.5.2.6] D 3.5.2.7 imidazolonepropionase E CH54_674 hutI; imidazolonepropionase K01468 hutI; imidazolonepropionase [EC:3.5.2.7] D 3.5.2.9 5-oxoprolinase (ATP-hydrolysing) E CH54_1156 lamB/YcsF family protein K07160 pxpA; 5-oxoprolinase (ATP-hydrolysing) subunit A [EC:3.5.2.9] E CH54_1158 allophanate hydrolase subunit 1 family protein K23123 pxpB; 5-oxoprolinase (ATP-hydrolysing) subunit B [EC:3.5.2.9] E CH54_1157 hypothetical protein K23124 pxpC; 5-oxoprolinase (ATP-hydrolysing) subunit C [EC:3.5.2.9] D 3.5.2.10 creatininase D 3.5.2.11 L-lysine-lactamase D 3.5.2.12 6-aminohexanoate-cyclic-dimer hydrolase D 3.5.2.13 2,5-dioxopiperazine hydrolase D 3.5.2.14 N-methylhydantoinase (ATP-hydrolysing) D 3.5.2.15 cyanuric acid amidohydrolase D 3.5.2.16 maleimide hydrolase D 3.5.2.17 hydroxyisourate hydrolase D 3.5.2.18 enamidase D 3.5.2.19 streptothricin hydrolase D 3.5.2.20 isatin hydrolase C 3.5.3 In linear amidines D 3.5.3.1 arginase D 3.5.3.2 guanidinoacetase D 3.5.3.3 creatinase D 3.5.3.4 allantoicase D 3.5.3.5 formimidoylaspartate deiminase D 3.5.3.6 arginine deiminase E CH54_1897 arcA; arginine deiminase K01478 arcA; arginine deiminase [EC:3.5.3.6] D 3.5.3.7 guanidinobutyrase D 3.5.3.8 formimidoylglutamase D 3.5.3.9 allantoate deiminase D 3.5.3.10 D-arginase D 3.5.3.11 agmatinase D 3.5.3.12 agmatine deiminase E CH54_3373 aguA; agmatine deiminase K10536 aguA; agmatine deiminase [EC:3.5.3.12] D 3.5.3.13 formimidoylglutamate deiminase E CH54_672 hutF; formiminoglutamate deiminase K05603 hutF; formimidoylglutamate deiminase [EC:3.5.3.13] D 3.5.3.14 amidinoaspartase D 3.5.3.15 protein-arginine deiminase D 3.5.3.16 methylguanidinase D 3.5.3.17 guanidinopropionase D 3.5.3.18 dimethylargininase E CH54_400 amidinotransferase family protein K01482 DDAH; dimethylargininase [EC:3.5.3.18] D 3.5.3.20 diguanidinobutanase D 3.5.3.21 methylenediurea deaminase D 3.5.3.22 proclavaminate amidinohydrolase D 3.5.3.23 N-succinylarginine dihydrolase E CH54_678 astB; succinylarginine dihydrolase K01484 astB; succinylarginine dihydrolase [EC:3.5.3.23] D 3.5.3.24 N1-aminopropylagmatine ureohydrolase D 3.5.3.25 Nomega-hydroxy-L-arginine amidinohydrolase D 3.5.3.26 (S)-ureidoglycine aminohydrolase C 3.5.4 In cyclic amidines D 3.5.4.1 cytosine deaminase E CH54_2294 amidohydrolase family protein K01485 codA; cytosine/creatinine deaminase [EC:3.5.4.1 3.5.4.21] D 3.5.4.2 adenine deaminase D 3.5.4.3 guanine deaminase D 3.5.4.4 adenosine deaminase E CH54_449 add; adenosine deaminase K01488 add; adenosine deaminase [EC:3.5.4.4] E CH54_1601 multi-copper polyphenol oxidoreductase laccase family protein K05810 LACC1; purine-nucleoside/S-methyl-5'-thioadenosine phosphorylase / adenosine deaminase [EC:2.4.2.1 2.4.2.28 3.5.4.4] D 3.5.4.5 cytidine deaminase E CH54_1002 cdd; cytidine deaminase K01489 cdd; cytidine deaminase [EC:3.5.4.5] D 3.5.4.6 AMP deaminase D 3.5.4.7 ADP deaminase D 3.5.4.8 aminoimidazolase D 3.5.4.9 methenyltetrahydrofolate cyclohydrolase E CH54_3763 tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain protein K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9] D 3.5.4.10 IMP cyclohydrolase E CH54_2896 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] D 3.5.4.11 pterin deaminase D 3.5.4.12 dCMP deaminase D 3.5.4.13 dCTP deaminase E CH54_992 dcd; deoxycytidine triphosphate deaminase K01494 dcd; dCTP deaminase [EC:3.5.4.13] D 3.5.4.15 guanosine deaminase D 3.5.4.16 GTP cyclohydrolase I E CH54_1028 folE; GTP cyclohydrolase I K01495 GCH1; GTP cyclohydrolase IA [EC:3.5.4.16] D 3.5.4.17 adenosine-phosphate deaminase D 3.5.4.18 ATP deaminase D 3.5.4.19 phosphoribosyl-AMP cyclohydrolase E CH54_985 hisE; phosphoribosyl-ATP diphosphatase K11755 hisIE; phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphohydrolase [EC:3.5.4.19 3.6.1.31] D 3.5.4.20 pyrithiamine deaminase D 3.5.4.21 creatinine deaminase E CH54_2294 amidohydrolase family protein K01485 codA; cytosine/creatinine deaminase [EC:3.5.4.1 3.5.4.21] D 3.5.4.22 1-pyrroline-4-hydroxy-2-carboxylate deaminase D 3.5.4.23 blasticidin-S deaminase D 3.5.4.24 sepiapterin deaminase D 3.5.4.25 GTP cyclohydrolase II E CH54_492 ribA; GTP cyclohydrolase II K01497 ribA; GTP cyclohydrolase II [EC:3.5.4.25] D 3.5.4.26 diaminohydroxyphosphoribosylaminopyrimidine deaminase E CH54_3663 ribD; riboflavin biosynthesis protein RibD K11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193] D 3.5.4.27 methenyltetrahydromethanopterin cyclohydrolase D 3.5.4.28 S-adenosylhomocysteine deaminase D 3.5.4.29 GTP cyclohydrolase IIa D 3.5.4.30 dCTP deaminase (dUMP-forming) D 3.5.4.31 S-methyl-5'-thioadenosine deaminase D 3.5.4.32 8-oxoguanine deaminase D 3.5.4.33 tRNA(adenine34) deaminase E CH54_1486 cytidine and deoxycytidylate deaminase zinc-binding region family protein K11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33] D 3.5.4.34 tRNAAla(adenine37) deaminase D 3.5.4.35 tRNA(cytosine8) deaminase D 3.5.4.36 mRNA(cytosine6666) deaminase D 3.5.4.37 double-stranded RNA adenine deaminase D 3.5.4.38 single-stranded DNA cytosine deaminase D 3.5.4.39 GTP cyclohydrolase IV D 3.5.4.40 aminodeoxyfutalosine deaminase D 3.5.4.41 5'-deoxyadenosine deaminase D 3.5.4.42 N-isopropylammelide isopropylaminohydrolase D 3.5.4.43 hydroxydechloroatrazine ethylaminohydrolase D 3.5.4.44 ectoine hydrolase D 3.5.4.45 melamine deaminase D 3.5.4.46 cAMP deaminase C 3.5.5 In nitriles D 3.5.5.1 nitrilase D 3.5.5.2 ricinine nitrilase D 3.5.5.4 cyanoalanine nitrilase D 3.5.5.5 arylacetonitrilase D 3.5.5.6 bromoxynil nitrilase D 3.5.5.7 aliphatic nitrilase D 3.5.5.8 thiocyanate hydrolase C 3.5.99 In other compounds D 3.5.99.1 riboflavinase D 3.5.99.2 aminopyrimidine aminohydrolase D 3.5.99.5 2-aminomuconate deaminase D 3.5.99.6 glucosamine-6-phosphate deaminase E CH54_1184 nagB; glucosamine-6-phosphate deaminase K02564 nagB; glucosamine-6-phosphate deaminase [EC:3.5.99.6] D 3.5.99.7 1-aminocyclopropane-1-carboxylate deaminase D 3.5.99.8 5-nitroanthranilic acid aminohydrolase D 3.5.99.9 2-nitroimidazole nitrohydrolase D 3.5.99.10 2-iminobutanoate/2-iminopropanoate deaminase E CH54_3003 reactive intermediate/imine deaminase family protein K09022 ridA; 2-iminobutanoate/2-iminopropanoate deaminase [EC:3.5.99.10] D 3.5.99.11 2-aminomuconate deaminase (2-hydroxymuconate-forming) B 3.6 Acting on acid anhydrides C 3.6.1 In phosphorus-containing anhydrides D 3.6.1.1 inorganic diphosphatase E CH54_2007 inorganic pyrophosphatase family protein K01507 ppa; inorganic pyrophosphatase [EC:3.6.1.1] D 3.6.1.2 trimetaphosphatase D 3.6.1.5 apyrase D 3.6.1.6 nucleoside diphosphate phosphatase D 3.6.1.7 acylphosphatase E CH54_25 acylphosphatase family protein K01512 acyP; acylphosphatase [EC:3.6.1.7] D 3.6.1.8 ATP diphosphatase D 3.6.1.9 nucleotide diphosphatase E CH54_1709 MazG family protein K04765 mazG; nucleoside triphosphate diphosphatase [EC:3.6.1.9] D 3.6.1.10 endopolyphosphatase D 3.6.1.11 exopolyphosphatase E CH54_2746 ppx/GppA phosphatase family protein K01524 ppx-gppA; exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [EC:3.6.1.11 3.6.1.40] E CH54_1362 ppx/GppA phosphatase family protein K01524 ppx-gppA; exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [EC:3.6.1.11 3.6.1.40] D 3.6.1.12 dCTP diphosphatase D 3.6.1.13 ADP-ribose diphosphatase E CH54_3122 nudix-type nucleoside diphosphatase, YffH/AdpP family protein K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-] D 3.6.1.14 adenosine-tetraphosphatase D 3.6.1.15 nucleoside-triphosphate phosphatase D 3.6.1.16 CDP-glycerol diphosphatase D 3.6.1.17 bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) D 3.6.1.18 FAD diphosphatase D 3.6.1.20 5'-acylphosphoadenosine hydrolase D 3.6.1.21 ADP-sugar diphosphatase D 3.6.1.22 NAD+ diphosphatase E CH54_2889 NADH pyrophosphatase-like rudimentary NUDIX domain protein K03426 NUDT12_13; NAD+ diphosphatase [EC:3.6.1.22] D 3.6.1.23 dUTP diphosphatase E CH54_2643 dut; dUTP diphosphatase family protein K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D 3.6.1.24 nucleoside phosphoacylhydrolase D 3.6.1.25 triphosphatase E CH54_3112 CYTH domain protein K18446 ygiF; triphosphatase [EC:3.6.1.25] D 3.6.1.26 CDP-diacylglycerol diphosphatase E CH54_2395 CDP-diacylglycerol pyrophosphatase family protein K01521 cdh; CDP-diacylglycerol pyrophosphatase [EC:3.6.1.26] D 3.6.1.27 undecaprenyl-diphosphate phosphatase E CH54_491 PAP2 superfamily protein K01096 pgpB; phosphatidylglycerophosphatase B [EC:3.1.3.27 3.6.1.75 3.1.3.4 3.6.1.27] E CH54_3109 uppP; undecaprenyl-diphosphatase UppP K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] E CH54_4040 PAP2 superfamily protein K19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27] D 3.6.1.28 thiamine-triphosphatase D 3.6.1.29 bis(5'-adenosyl)-triphosphatase D 3.6.1.31 phosphoribosyl-ATP diphosphatase E CH54_985 hisE; phosphoribosyl-ATP diphosphatase K11755 hisIE; phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphohydrolase [EC:3.5.4.19 3.6.1.31] D 3.6.1.39 thymidine-triphosphatase D 3.6.1.40 guanosine-5'-triphosphate,3'-diphosphate phosphatase E CH54_2746 ppx/GppA phosphatase family protein K01524 ppx-gppA; exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [EC:3.6.1.11 3.6.1.40] E CH54_1362 ppx/GppA phosphatase family protein K01524 ppx-gppA; exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [EC:3.6.1.11 3.6.1.40] D 3.6.1.41 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) E CH54_1819 apaH; Diadenosine tetraphosphatase K01525 apaH; bis(5'-nucleosyl)-tetraphosphatase (symmetrical) [EC:3.6.1.41] D 3.6.1.42 guanosine-diphosphatase D 3.6.1.43 dolichyldiphosphatase D 3.6.1.44 oligosaccharide-diphosphodolichol diphosphatase D 3.6.1.45 UDP-sugar diphosphatase E CH54_3745 hypothetical protein K11751 ushA; 5'-nucleotidase / UDP-sugar diphosphatase [EC:3.1.3.5 3.6.1.45] D 3.6.1.52 diphosphoinositol-polyphosphate diphosphatase D 3.6.1.53 Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase D 3.6.1.54 UDP-2,3-diacylglucosamine diphosphatase E CH54_3759 lpxH; UDP-2,3-diacylglucosamine diphosphatase K03269 lpxH; UDP-2,3-diacylglucosamine hydrolase [EC:3.6.1.54] D 3.6.1.55 8-oxo-dGTP diphosphatase E CH54_1769 mutator mutT family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] E CH54_4011 NUDIX domain protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D 3.6.1.56 2-hydroxy-dATP diphosphatase D 3.6.1.57 UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose hydrolase D 3.6.1.58 8-oxo-dGDP phosphatase D 3.6.1.59 5'-(N7-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase D 3.6.1.60 diadenosine hexaphosphate hydrolase (AMP-forming) D 3.6.1.61 diadenosine hexaphosphate hydrolase (ATP-forming) D 3.6.1.62 5'-(N7-methylguanosine 5'-triphospho)-[mRNA] hydrolase D 3.6.1.63 alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase E CH54_1952 phnM; phosphonate metabolism protein PhnM K06162 phnM; alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase [EC:3.6.1.63] D 3.6.1.64 inosine diphosphate phosphatase D 3.6.1.65 (d)CTP diphosphatase E CH54_567 NUDIX domain protein K08320 nudG; (d)CTP diphosphatase [EC:3.6.1.65] D 3.6.1.66 XTP/dITP diphosphatase E CH54_3367 rdgB; non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family K01519 rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66] D 3.6.1.67 dihydroneopterin triphosphate diphosphatase E CH54_625 NUDIX domain protein K08310 nudB; dihydroneopterin triphosphate diphosphatase [EC:3.6.1.67] D 3.6.1.68 geranyl diphosphate phosphohydrolase D 3.6.1.69 8-oxo-(d)GTP phosphatase D 3.6.1.70 guanosine-5'-diphospho-5'-[DNA] diphosphatase D 3.6.1.71 adenosine-5'-diphospho-5'-[DNA] diphosphatase D 3.6.1.72 DNA-3'-diphospho-5'-guanosine diphosphatase D 3.6.1.73 inosine/xanthosine triphosphatase E CH54_1853 hypothetical protein K01529 yjjX; inosine/xanthosine triphosphatase [EC:3.6.1.73] D 3.6.1.74 mRNA 5'-phosphatase D 3.6.1.75 diacylglycerol diphosphate phosphatase E CH54_491 PAP2 superfamily protein K01096 pgpB; phosphatidylglycerophosphatase B [EC:3.1.3.27 3.6.1.75 3.1.3.4 3.6.1.27] D 3.6.1.76 prenyl-diphosphate phosphatase C 3.6.2 In sulfonyl-containing anhydrides D 3.6.2.1 adenylylsulfatase D 3.6.2.2 phosphoadenylylsulfatase C 3.6.4 Acting on acid anhydrides to facilitate cellular and subcellular movement D 3.6.4.6 vesicle-fusing ATPase D 3.6.4.7 peroxisome-assembly ATPase D 3.6.4.10 non-chaperonin molecular chaperone ATPase D 3.6.4.13 RNA helicase E CH54_365 hrpA; RNA helicase HrpA K03578 hrpA; ATP-dependent helicase HrpA [EC:3.6.4.13] E CH54_1725 hrpB; ATP-dependent helicase HrpB K03579 hrpB; ATP-dependent helicase HrpB [EC:3.6.4.13] E CH54_2747 DEAD/DEAH box helicase family protein K03732 rhlB; ATP-dependent RNA helicase RhlB [EC:3.6.4.13] E CH54_1509 DEAD/DEAH box helicase family protein K05590 srmB; ATP-dependent RNA helicase SrmB [EC:3.6.4.13] E CH54_171 DEAD/DEAH box helicase family protein K05591 dbpA; ATP-dependent RNA helicase DbpA [EC:3.6.4.13] E CH54_1972 DEAD/DEAH box helicase family protein K05592 deaD; ATP-dependent RNA helicase DeaD [EC:3.6.4.13] E CH54_1089 hypothetical protein K11927 rhlE; ATP-dependent RNA helicase RhlE [EC:3.6.4.13] C 3.6.5 Acting on GTP to facilitate cellular and subcellular movement D 3.6.5.1 heterotrimeric G-protein GTPase D 3.6.5.2 small monomeric GTPase D 3.6.5.3 protein-synthesizing GTPase D 3.6.5.4 signal-recognition-particle GTPase E CH54_1615 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4] D 3.6.5.5 dynamin GTPase D 3.6.5.6 tubulin GTPase B 3.7 Acting on carbon-carbon bonds C 3.7.1 In ketonic substances D 3.7.1.1 oxaloacetase D 3.7.1.2 fumarylacetoacetase D 3.7.1.3 kynureninase D 3.7.1.4 phloretin hydrolase D 3.7.1.5 acylpyruvate hydrolase D 3.7.1.6 acetylpyruvate hydrolase D 3.7.1.7 beta-diketone hydrolase D 3.7.1.8 2,6-dioxo-6-phenylhexa-3-enoate hydrolase D 3.7.1.9 2-hydroxymuconate-6-semialdehyde hydrolase D 3.7.1.10 cyclohexane-1,3-dione hydrolase D 3.7.1.11 cyclohexane-1,2-dione hydrolase D 3.7.1.12 cobalt-precorrin 5A hydrolase E CH54_930 cobalamin synthesis G family protein K02189 cbiG; cobalt-precorrin 5A hydrolase [EC:3.7.1.12] D 3.7.1.13 2-hydroxy-6-oxo-6-(2-aminophenyl)hexa-2,4-dienoate hydrolase D 3.7.1.14 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase D 3.7.1.17 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase D 3.7.1.18 6-oxocamphor hydrolase D 3.7.1.19 2,6-dihydroxypseudooxynicotine hydrolase D 3.7.1.20 3-fumarylpyruvate hydrolase D 3.7.1.21 6-oxocyclohex-1-ene-1-carbonyl-CoA hydratase D 3.7.1.22 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (ring-opening) E CH54_2366 iolD; 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase K03336 iolD; 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (decyclizing) [EC:3.7.1.22] D 3.7.1.23 maleylpyruvate hydrolase D 3.7.1.24 2,4-diacetylphloroglucinol hydrolase D 3.7.1.25 2-hydroxy-6-oxohepta-2,4-dienoate hydrolase D 3.7.1.26 2,4-didehydro-3-deoxy-L-rhamnonate hydrolase D 3.7.1.28 3-oxoisoapionate-4-phosphate transcarboxylase/hydrolase B 3.8 Acting on halide bonds C 3.8.1 In carbon-halide compounds D 3.8.1.2 (S)-2-haloacid dehalogenase D 3.8.1.3 haloacetate dehalogenase D 3.8.1.5 haloalkane dehalogenase D 3.8.1.6 4-chlorobenzoate dehalogenase D 3.8.1.7 4-chlorobenzoyl-CoA dehalogenase D 3.8.1.8 atrazine chlorohydrolase D 3.8.1.9 (R)-2-haloacid dehalogenase D 3.8.1.10 2-haloacid dehalogenase (configuration-inverting) D 3.8.1.11 2-haloacid dehalogenase (configuration-retaining) C 3.8.2 In phosphorus-halide compounds D 3.8.2.2 diisopropyl-fluorophosphatase B 3.9 Acting on phosphorus-nitrogen bonds C 3.9.1 Acting on phosphorus-nitrogen bonds (only sub-subclass identified to date) D 3.9.1.1 phosphoamidase D 3.9.1.2 protein arginine phosphatase D 3.9.1.3 phosphohistidine phosphatase B 3.10 Acting on sulfur-nitrogen bonds C 3.10.1 Acting on sulfur-nitrogen bonds (only sub-subclass identified to date) D 3.10.1.1 N-sulfoglucosamine sulfohydrolase D 3.10.1.2 cyclamate sulfohydrolase B 3.11 Acting on carbon-phosphorus bonds C 3.11.1 Acting on carbon-phosphorus bonds (only sub-subclass identified to date) D 3.11.1.1 phosphonoacetaldehyde hydrolase D 3.11.1.2 phosphonoacetate hydrolase D 3.11.1.3 phosphonopyruvate hydrolase B 3.12 Acting on sulfur-sulfur bonds C 3.12.1 Acting on sulfur-sulfur bonds (only sub-subclass identified to date) D 3.12.1.1 trithionate hydrolase B 3.13 Acting on carbon-sulfur bonds C 3.13.1 Acting on carbon-sulfur bonds D 3.13.1.1 UDP-sulfoquinovose synthase D 3.13.1.3 2'-hydroxybiphenyl-2-sulfinate desulfinase D 3.13.1.4 3-sulfinopropanoyl-CoA desulfinase D 3.13.1.5 carbon disulfide hydrolase D 3.13.1.6 [CysO sulfur-carrier protein]-S-L-cysteine hydrolase D 3.13.1.7 carbonyl sulfide hydrolase D 3.13.1.9 S-inosyl-L-homocysteine hydrolase C 3.13.2 Thioether and trialkylsulfonium hydrolases D 3.13.2.1 adenosylhomocysteinase D 3.13.2.3 (R)-S-adenosyl-L-methionine hydrolase (adenosine-forming) # A4. Lyases B 4.1 Carbon-carbon lyases C 4.1.1 Carboxy-lyases D 4.1.1.1 pyruvate decarboxylase D 4.1.1.2 oxalate decarboxylase D 4.1.1.4 acetoacetate decarboxylase D 4.1.1.5 acetolactate decarboxylase D 4.1.1.6 cis-aconitate decarboxylase D 4.1.1.7 benzoylformate decarboxylase D 4.1.1.8 oxalyl-CoA decarboxylase D 4.1.1.9 malonyl-CoA decarboxylase D 4.1.1.11 aspartate 1-decarboxylase E CH54_1734 panD; aspartate 1-decarboxylase K01579 panD; aspartate 1-decarboxylase [EC:4.1.1.11] D 4.1.1.12 aspartate 4-decarboxylase D 4.1.1.14 valine decarboxylase D 4.1.1.15 glutamate decarboxylase E CH54_3092 glutamate decarboxylase K01580 E4.1.1.15; glutamate decarboxylase [EC:4.1.1.15] D 4.1.1.16 hydroxyglutamate decarboxylase D 4.1.1.17 ornithine decarboxylase E CH54_3357 beta-eliminating lyase family protein K01581 E4.1.1.17; ornithine decarboxylase [EC:4.1.1.17] E CH54_1964 beta-eliminating lyase family protein K01581 E4.1.1.17; ornithine decarboxylase [EC:4.1.1.17] D 4.1.1.18 lysine decarboxylase D 4.1.1.19 arginine decarboxylase E CH54_3386 speA; arginine decarboxylase K01585 speA; arginine decarboxylase [EC:4.1.1.19] D 4.1.1.20 diaminopimelate decarboxylase E CH54_3476 lysA; diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20] D 4.1.1.21 phosphoribosylaminoimidazole carboxylase D 4.1.1.22 histidine decarboxylase D 4.1.1.23 orotidine-5'-phosphate decarboxylase E CH54_486 pyrF; orotidine 5'-phosphate decarboxylase K01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23] D 4.1.1.24 aminobenzoate decarboxylase D 4.1.1.25 tyrosine decarboxylase D 4.1.1.28 aromatic-L-amino-acid decarboxylase D 4.1.1.29 sulfinoalanine decarboxylase D 4.1.1.30 pantothenoylcysteine decarboxylase D 4.1.1.31 phosphoenolpyruvate carboxylase E CH54_2695 phosphoenolpyruvate carboxylase family protein K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31] D 4.1.1.32 phosphoenolpyruvate carboxykinase (GTP) D 4.1.1.33 diphosphomevalonate decarboxylase D 4.1.1.34 dehydro-L-gulonate decarboxylase D 4.1.1.35 UDP-glucuronate decarboxylase D 4.1.1.36 phosphopantothenoylcysteine decarboxylase E CH54_2644 coaBC; phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase K13038 coaBC; phosphopantothenoylcysteine decarboxylase / phosphopantothenate---cysteine ligase [EC:4.1.1.36 6.3.2.5] D 4.1.1.37 uroporphyrinogen decarboxylase E CH54_2890 hemE; uroporphyrinogen decarboxylase K01599 hemE; uroporphyrinogen decarboxylase [EC:4.1.1.37] D 4.1.1.38 phosphoenolpyruvate carboxykinase (diphosphate) D 4.1.1.39 ribulose-bisphosphate carboxylase D 4.1.1.40 hydroxypyruvate decarboxylase D 4.1.1.42 carnitine decarboxylase D 4.1.1.43 phenylpyruvate decarboxylase D 4.1.1.44 4-carboxymuconolactone decarboxylase D 4.1.1.45 aminocarboxymuconate-semialdehyde decarboxylase D 4.1.1.46 o-pyrocatechuate decarboxylase D 4.1.1.47 tartronate-semialdehyde synthase D 4.1.1.48 indole-3-glycerol-phosphate synthase E CH54_528 indole-3-glycerol phosphate synthase family protein K13498 trpCF; indole-3-glycerol phosphate synthase / phosphoribosylanthranilate isomerase [EC:4.1.1.48 5.3.1.24] D 4.1.1.49 phosphoenolpyruvate carboxykinase (ATP) E CH54_2318 pckA; phosphoenolpyruvate carboxykinase K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49] D 4.1.1.50 adenosylmethionine decarboxylase E CH54_1744 speD; S-adenosylmethionine decarboxylase proenzyme K01611 speD; S-adenosylmethionine decarboxylase [EC:4.1.1.50] D 4.1.1.51 3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-decarboxylase D 4.1.1.52 6-methylsalicylate decarboxylase D 4.1.1.53 phenylalanine decarboxylase D 4.1.1.54 dihydroxyfumarate decarboxylase D 4.1.1.55 4,5-dihydroxyphthalate decarboxylase D 4.1.1.56 3-oxolaurate decarboxylase D 4.1.1.57 methionine decarboxylase D 4.1.1.58 orsellinate decarboxylase D 4.1.1.59 gallate decarboxylase D 4.1.1.60 stipitatonate decarboxylase D 4.1.1.61 4-hydroxybenzoate decarboxylase D 4.1.1.62 gentisate decarboxylase D 4.1.1.63 protocatechuate decarboxylase D 4.1.1.64 2,2-dialkylglycine decarboxylase (pyruvate) D 4.1.1.65 phosphatidylserine decarboxylase E CH54_2050 psd; phosphatidylserine decarboxylase K01613 psd; phosphatidylserine decarboxylase [EC:4.1.1.65] D 4.1.1.66 uracil-5-carboxylate decarboxylase D 4.1.1.67 UDP-galacturonate decarboxylase D 4.1.1.68 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase D 4.1.1.69 3,4-dihydroxyphthalate decarboxylase D 4.1.1.71 2-oxoglutarate decarboxylase D 4.1.1.72 branched-chain-2-oxoacid decarboxylase D 4.1.1.73 tartrate decarboxylase D 4.1.1.74 indolepyruvate decarboxylase D 4.1.1.75 5-guanidino-2-oxopentanoate decarboxylase D 4.1.1.76 arylmalonate decarboxylase D 4.1.1.77 2-oxo-3-hexenedioate decarboxylase D 4.1.1.78 acetylenedicarboxylate decarboxylase D 4.1.1.79 sulfopyruvate decarboxylase D 4.1.1.80 4-hydroxyphenylpyruvate decarboxylase D 4.1.1.81 threonine-phosphate decarboxylase E CH54_962 threonine-phosphate decarboxylase K04720 cobD; threonine-phosphate decarboxylase [EC:4.1.1.81] D 4.1.1.82 phosphonopyruvate decarboxylase D 4.1.1.83 4-hydroxyphenylacetate decarboxylase D 4.1.1.84 D-dopachrome decarboxylase D 4.1.1.85 3-dehydro-L-gulonate-6-phosphate decarboxylase D 4.1.1.86 diaminobutyrate decarboxylase D 4.1.1.87 malonyl-[malonate decarboxylase] decarboxylase D 4.1.1.88 biotin-independent malonate decarboxylase D 4.1.1.90 peptidyl-glutamate 4-carboxylase D 4.1.1.91 salicylate decarboxylase D 4.1.1.92 indole-3-carboxylate decarboxylase D 4.1.1.93 pyrrole-2-carboxylate decarboxylase D 4.1.1.94 ethylmalonyl-CoA decarboxylase D 4.1.1.95 L-glutamyl-[BtrI acyl-carrier protein] decarboxylase D 4.1.1.96 carboxynorspermidine decarboxylase D 4.1.1.97 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase D 4.1.1.98 4-hydroxy-3-polyprenylbenzoate decarboxylase E CH54_2849 decarboxylase, UbiD family protein K03182 ubiD; 4-hydroxy-3-polyprenylbenzoate decarboxylase [EC:4.1.1.98] D 4.1.1.99 phosphomevalonate decarboxylase D 4.1.1.100 prephenate decarboxylase D 4.1.1.101 malolactic enzyme D 4.1.1.102 phenacrylate decarboxylase D 4.1.1.103 gamma-resorcylate decarboxylase D 4.1.1.104 3-dehydro-4-phosphotetronate decarboxylase E CH54_715 hypothetical protein K22130 otnC; 3-dehydro-4-phosphotetronate decarboxylase [EC:4.1.1.104] D 4.1.1.105 L-tryptophan decarboxylase D 4.1.1.106 fatty acid photodecarboxylase D 4.1.1.107 3,4-dihydroxyphenylacetaldehyde synthase D 4.1.1.108 4-hydroxyphenylacetaldehyde synthase D 4.1.1.109 phenylacetaldehyde synthase D 4.1.1.110 bisphosphomevalonate decarboxylase D 4.1.1.111 siroheme decarboxylase D 4.1.1.112 oxaloacetate decarboxylase D 4.1.1.113 trans-aconitate decarboxylase D 4.1.1.114 cis-3-alkyl-4-alkyloxetan-2-one decarboxylase D 4.1.1.115 indoleacetate decarboxylase D 4.1.1.116 D-ornithine/D-lysine decarboxylase D 4.1.1.117 2-[(L-alanin-3-ylcarbamoyl)methyl]-2-hydroxybutanedioate decarboxylase D 4.1.1.118 isophthalyl-CoA decarboxylase D 4.1.1.119 phenylacetate decarboxylase D 4.1.1.120 3-oxoisoapionate decarboxylase D 4.1.1.121 3-oxoisoapionate-4-phosphate decarboxylase D 4.1.1.122 L-cysteate decarboxylase D 4.1.1.123 phenyl-phosphate phosphatase/carboxylase D 4.1.1.124 malonyl-[acp] decarboxylase D 4.1.1.125 4-carboxy-3-alkylbut-2-enoyl-[acp] decarboxylase D 4.1.1.126 anhydromevalonate phosphate decarboxylase C 4.1.2 Aldehyde-lyases D 4.1.2.2 ketotetrose-phosphate aldolase D 4.1.2.4 deoxyribose-phosphate aldolase E CH54_4039 deoC; deoxyribose-phosphate aldolase K01619 deoC; deoxyribose-phosphate aldolase [EC:4.1.2.4] E CH54_1868 deoC; deoxyribose-phosphate aldolase K01619 deoC; deoxyribose-phosphate aldolase [EC:4.1.2.4] D 4.1.2.5 L-threonine aldolase D 4.1.2.8 indole-3-glycerol-phosphate lyase D 4.1.2.9 phosphoketolase D 4.1.2.10 (R)-mandelonitrile lyase D 4.1.2.11 hydroxymandelonitrile lyase D 4.1.2.12 2-dehydropantoate aldolase D 4.1.2.13 fructose-bisphosphate aldolase E CH54_3392 fbaA; fructose-bisphosphate aldolase, class II K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] D 4.1.2.14 2-dehydro-3-deoxy-phosphogluconate aldolase E CH54_611 eda; 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase family protein K01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42] D 4.1.2.17 L-fuculose-phosphate aldolase D 4.1.2.18 2-dehydro-3-deoxy-L-pentonate aldolase D 4.1.2.19 rhamnulose-1-phosphate aldolase D 4.1.2.20 2-dehydro-3-deoxyglucarate aldolase E CH54_2079 garL; 2-dehydro-3-deoxyglucarate aldolase K01630 garL; 2-dehydro-3-deoxyglucarate aldolase [EC:4.1.2.20] D 4.1.2.21 2-dehydro-3-deoxy-6-phosphogalactonate aldolase D 4.1.2.22 fructose-6-phosphate phosphoketolase D 4.1.2.23 3-deoxy-D-manno-octulosonate aldolase D 4.1.2.24 dimethylaniline-N-oxide aldolase D 4.1.2.25 dihydroneopterin aldolase E CH54_3108 folB; dihydroneopterin aldolase K01633 folB; 7,8-dihydroneopterin aldolase/epimerase/oxygenase [EC:4.1.2.25 5.1.99.8 1.13.11.81] D 4.1.2.26 phenylserine aldolase D 4.1.2.27 sphinganine-1-phosphate aldolase D 4.1.2.28 2-dehydro-3-deoxy-D-pentonate aldolase D 4.1.2.29 5-dehydro-2-deoxyphosphogluconate aldolase D 4.1.2.32 trimethylamine-oxide aldolase D 4.1.2.33 fucosterol-epoxide lyase D 4.1.2.34 4-(2-carboxyphenyl)-2-oxobut-3-enoate aldolase D 4.1.2.35 propioin synthase D 4.1.2.36 lactate aldolase D 4.1.2.38 benzoin aldolase D 4.1.2.40 tagatose-bisphosphate aldolase D 4.1.2.42 D-threonine aldolase D 4.1.2.43 3-hexulose-6-phosphate synthase D 4.1.2.44 2,3-epoxybenzoyl-CoA dihydrolase D 4.1.2.45 trans-o-hydroxybenzylidenepyruvate hydratase-aldolase D 4.1.2.46 aliphatic (R)-hydroxynitrile lyase D 4.1.2.47 (S)-hydroxynitrile lyase D 4.1.2.48 low-specificity L-threonine aldolase E CH54_4060 beta-eliminating lyase family protein K01620 ltaE; threonine aldolase [EC:4.1.2.48] D 4.1.2.49 L-allo-threonine aldolase D 4.1.2.50 6-carboxytetrahydropterin synthase E CH54_1700 queD; queuosine biosynthesis protein QueD K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50] D 4.1.2.51 2-dehydro-3-deoxy-D-gluconate aldolase D 4.1.2.52 4-hydroxy-2-oxoheptanedioate aldolase D 4.1.2.53 2-keto-3-deoxy-L-rhamnonate aldolase D 4.1.2.54 L-threo-3-deoxy-hexylosonate aldolase D 4.1.2.55 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase D 4.1.2.56 2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate synthase D 4.1.2.57 sulfofructosephosphate aldolase D 4.1.2.58 2-dehydro-3,6-dideoxy-6-sulfogluconate aldolase D 4.1.2.59 dihydroneopterin phosphate aldolase D 4.1.2.60 dihydroneopterin triphosphate aldolase D 4.1.2.61 feruloyl-CoA hydratase/lyase D 4.1.2.62 5-deoxyribulose 1-phosphate aldolase D 4.1.2.63 2-hydroxyacyl-CoA lyase D 4.1.2.64 2-dehydro-3-deoxy-L-fuconate aldolase C 4.1.3 Oxo-acid-lyases D 4.1.3.1 isocitrate lyase E CH54_2906 aceA; isocitrate lyase K01637 E4.1.3.1; isocitrate lyase [EC:4.1.3.1] D 4.1.3.3 N-acetylneuraminate lyase E CH54_1310 dihydrodipicolinate synthetase family protein K01639 E4.1.3.3; N-acetylneuraminate lyase [EC:4.1.3.3] D 4.1.3.4 hydroxymethylglutaryl-CoA lyase D 4.1.3.6 citrate (pro-3S)-lyase D 4.1.3.13 oxalomalate lyase D 4.1.3.14 L-erythro-3-hydroxyaspartate aldolase D 4.1.3.16 4-hydroxy-2-oxoglutarate aldolase D 4.1.3.17 4-hydroxy-4-methyl-2-oxoglutarate aldolase D 4.1.3.22 citramalate lyase D 4.1.3.24 malyl-CoA lyase D 4.1.3.25 (S)-citramalyl-CoA lyase D 4.1.3.26 3-hydroxy-3-isohexenylglutaryl-CoA lyase D 4.1.3.27 anthranilate synthase E CH54_525 trpE; anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27] E CH54_526 glutamine amidotransferase of anthranilate synthase/aminodeoxychorismate synthase family protein K01658 trpG; anthranilate synthase component II [EC:4.1.3.27] D 4.1.3.30 methylisocitrate lyase D 4.1.3.32 2,3-dimethylmalate lyase D 4.1.3.34 citryl-CoA lyase E CH54_861 hpcH/HpaI aldolase/citrate lyase family protein K01644 citE; citrate lyase subunit beta / citryl-CoA lyase [EC:4.1.3.34] D 4.1.3.35 (1-hydroxycyclohexan-1-yl)acetyl-CoA lyase D 4.1.3.36 1,4-dihydroxy-2-naphthoyl-CoA synthase E CH54_3953 menB; naphthoate synthase K01661 menB; naphthoate synthase [EC:4.1.3.36] D 4.1.3.38 aminodeoxychorismate lyase E CH54_81 pabC; aminodeoxychorismate lyase K02619 pabC; 4-amino-4-deoxychorismate lyase [EC:4.1.3.38] D 4.1.3.39 4-hydroxy-2-oxovalerate aldolase D 4.1.3.40 chorismate lyase E CH54_2924 chorismate lyase family protein K03181 ubiC; chorismate lyase [EC:4.1.3.40] D 4.1.3.41 3-hydroxy-D-aspartate aldolase D 4.1.3.42 (4S)-4-hydroxy-2-oxoglutarate aldolase E CH54_611 eda; 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase family protein K01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42] D 4.1.3.43 4-hydroxy-2-oxohexanoate aldolase D 4.1.3.44 tRNA 4-demethylwyosine synthase (AdoMet-dependent) D 4.1.3.45 3-hydroxybenzoate synthase D 4.1.3.46 (R)-citramalyl-CoA lyase C 4.1.99 Other carbon-carbon lyases D 4.1.99.1 tryptophanase E CH54_1801 tnaA; tryptophanase K01667 tnaA; tryptophanase [EC:4.1.99.1] D 4.1.99.2 tyrosine phenol-lyase D 4.1.99.3 deoxyribodipyrimidine photo-lyase E CH54_1161 FAD binding domain of DNA photolyase family protein K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] D 4.1.99.5 aldehyde oxygenase (deformylating) D 4.1.99.11 benzylsuccinate synthase D 4.1.99.12 3,4-dihydroxy-2-butanone-4-phosphate synthase E CH54_3117 ribB; 3,4-dihydroxy-2-butanone-4-phosphate synthase K02858 ribB; 3,4-dihydroxy 2-butanone 4-phosphate synthase [EC:4.1.99.12] D 4.1.99.13 (6-4)DNA photolyase D 4.1.99.14 spore photoproduct lyase D 4.1.99.16 geosmin synthase D 4.1.99.17 phosphomethylpyrimidine synthase E CH54_2887 thiC; phosphomethylpyrimidine synthase K03147 thiC; phosphomethylpyrimidine synthase [EC:4.1.99.17] D 4.1.99.19 2-iminoacetate synthase E CH54_2882 thiH; thiazole biosynthesis protein ThiH K03150 thiH; 2-iminoacetate synthase [EC:4.1.99.19] D 4.1.99.20 3-amino-4-hydroxybenzoate synthase D 4.1.99.22 GTP 3',8-cyclase E CH54_1099 moaA; molybdenum cofactor biosynthesis protein A K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22] D 4.1.99.23 5-hydroxybenzimidazole synthase D 4.1.99.24 L-tyrosine isonitrile synthase D 4.1.99.25 L-tryptophan isonitrile synthase D 4.1.99.26 3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one synthase D 4.1.99.27 cyclopenase D 4.1.99.28 3'-dehydrocarminate deglycosidase B 4.2 Carbon-oxygen lyases C 4.2.1 Hydro-lyases D 4.2.1.1 carbonic anhydrase E CH54_1738 carbonic anhydrase family protein K01673 cynT; carbonic anhydrase [EC:4.2.1.1] E CH54_3453 Tat (twin-arginine translocation) pathway signal sequence domain protein K01673 cynT; carbonic anhydrase [EC:4.2.1.1] D 4.2.1.2 fumarate hydratase E CH54_1636 hydrolyase, tartrate alpha subunit/fumarate, Fe-S type domain protein K01676 E4.2.1.2A; fumarate hydratase, class I [EC:4.2.1.2] E CH54_440 fumC; fumarate hydratase, class II K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2] D 4.2.1.3 aconitate hydratase E CH54_493 acnA; aconitate hydratase 1 K01681 ACO; aconitate hydratase [EC:4.2.1.3] E CH54_1750 acnB; aconitate hydratase 2 K01682 acnB; aconitate hydratase 2 / 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99] D 4.2.1.5 arabinonate dehydratase D 4.2.1.6 galactonate dehydratase D 4.2.1.7 altronate dehydratase E CH54_3080 hypothetical protein K01685 uxaA; altronate hydrolase [EC:4.2.1.7] D 4.2.1.8 mannonate dehydratase E CH54_4006 uxuA; mannonate dehydratase K01686 uxuA; mannonate dehydratase [EC:4.2.1.8] D 4.2.1.9 dihydroxy-acid dehydratase E CH54_2730 ilvD; dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9] D 4.2.1.10 3-dehydroquinate dehydratase E CH54_2965 aroQ; 3-dehydroquinate dehydratase, type II K03786 aroQ; 3-dehydroquinate dehydratase II [EC:4.2.1.10] D 4.2.1.11 phosphopyruvate hydratase E CH54_1707 eno; phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] D 4.2.1.12 phosphogluconate dehydratase E CH54_3947 edd; phosphogluconate dehydratase K01690 edd; phosphogluconate dehydratase [EC:4.2.1.12] D 4.2.1.17 enoyl-CoA hydratase E CH54_3859 fadJ; fatty oxidation complex, alpha subunit FadJ K01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3] E CH54_2852 fadB; fatty oxidation complex, alpha subunit FadB K01825 fadB; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase [EC:1.1.1.35 4.2.1.17 5.1.2.3 5.3.3.8] D 4.2.1.18 methylglutaconyl-CoA hydratase D 4.2.1.19 imidazoleglycerol-phosphate dehydratase E CH54_981 hisB; histidinol-phosphatase K01089 hisB; imidazoleglycerol-phosphate dehydratase / histidinol-phosphatase [EC:4.2.1.19 3.1.3.15] D 4.2.1.20 tryptophan synthase E CH54_530 trpA; tryptophan synthase, alpha subunit K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20] E CH54_529 trpB; tryptophan synthase, beta subunit K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20] D 4.2.1.22 cystathionine beta-synthase E CH54_4034 CBS domain protein K01697 CBS; cystathionine beta-synthase [EC:4.2.1.22] D 4.2.1.24 porphobilinogen synthase E CH54_2847 delta-aminolevulinic acid dehydratase family protein K01698 hemB; porphobilinogen synthase [EC:4.2.1.24] D 4.2.1.25 L-arabinonate dehydratase D 4.2.1.27 acetylenecarboxylate hydratase D 4.2.1.28 propanediol dehydratase E CH54_943 dehydratase large subunit K01699 pduC; propanediol dehydratase large subunit [EC:4.2.1.28] E CH54_944 dehydratase medium subunit K13919 pduD; propanediol dehydratase medium subunit [EC:4.2.1.28] E CH54_945 dehydratase small subunit K13920 pduE; propanediol dehydratase small subunit [EC:4.2.1.28] D 4.2.1.30 glycerol dehydratase D 4.2.1.31 maleate hydratase D 4.2.1.32 L(+)-tartrate dehydratase D 4.2.1.33 3-isopropylmalate dehydratase E CH54_1798 leuC; 3-isopropylmalate dehydratase, large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35] E CH54_1799 leuD; 3-isopropylmalate dehydratase, small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35] D 4.2.1.34 (S)-2-methylmalate dehydratase D 4.2.1.35 (R)-2-methylmalate dehydratase E CH54_1798 leuC; 3-isopropylmalate dehydratase, large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35] E CH54_1799 leuD; 3-isopropylmalate dehydratase, small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35] D 4.2.1.36 homoaconitate hydratase D 4.2.1.39 gluconate dehydratase D 4.2.1.40 glucarate dehydratase D 4.2.1.41 5-dehydro-4-deoxyglucarate dehydratase D 4.2.1.42 galactarate dehydratase E CH54_2075 garD; galactarate dehydratase K01708 garD; galactarate dehydratase [EC:4.2.1.42] D 4.2.1.43 2-dehydro-3-deoxy-L-arabinonate dehydratase D 4.2.1.44 myo-inosose-2 dehydratase E CH54_2363 iolE; myo-inosose-2 dehydratase K03335 iolE; inosose dehydratase [EC:4.2.1.44] D 4.2.1.45 CDP-glucose 4,6-dehydratase D 4.2.1.46 dTDP-glucose 4,6-dehydratase E CH54_2754 rfbB; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] D 4.2.1.47 GDP-mannose 4,6-dehydratase D 4.2.1.48 D-glutamate cyclase D 4.2.1.49 urocanate hydratase E CH54_2433 hutU; urocanate hydratase K01712 hutU; urocanate hydratase [EC:4.2.1.49] D 4.2.1.50 pyrazolylalanine synthase D 4.2.1.51 prephenate dehydratase E CH54_1657 bacterial extracellular solute-binding s, 3 family protein K01713 pheC; cyclohexadienyl dehydratase [EC:4.2.1.51 4.2.1.91] E CH54_1605 chorismate mutase K14170 pheA; chorismate mutase / prephenate dehydratase [EC:5.4.99.5 4.2.1.51] D 4.2.1.53 oleate hydratase D 4.2.1.54 lactoyl-CoA dehydratase D 4.2.1.55 3-hydroxybutyryl-CoA dehydratase D 4.2.1.56 itaconyl-CoA hydratase D 4.2.1.57 isohexenylglutaconyl-CoA hydratase D 4.2.1.59 3-hydroxyacyl-[acyl-carrier-protein] dehydratase E CH54_9 fabA; beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA K01716 fabA; 3-hydroxyacyl-[acyl-carrier protein] dehydratase / trans-2-decenoyl-[acyl-carrier protein] isomerase [EC:4.2.1.59 5.3.3.14] E CH54_3531 fabZ; beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59] D 4.2.1.62 5alpha-hydroxysteroid dehydratase D 4.2.1.65 3-cyanoalanine hydratase D 4.2.1.66 cyanide hydratase D 4.2.1.67 D-fuconate dehydratase D 4.2.1.68 L-fuconate dehydratase D 4.2.1.69 cyanamide hydratase D 4.2.1.70 pseudouridylate synthase E CH54_3620 indigoidine synthase A like family protein K16329 psuG; pseudouridylate synthase [EC:4.2.1.70] D 4.2.1.73 protoaphin-aglucone dehydratase (cyclizing) D 4.2.1.74 medium-chain-enoyl-CoA hydratase D 4.2.1.75 uroporphyrinogen-III synthase E CH54_2771 uroporphyrinogen-III synthase HemD family protein K01719 hemD; uroporphyrinogen-III synthase [EC:4.2.1.75] D 4.2.1.76 UDP-glucose 4,6-dehydratase D 4.2.1.77 trans-L-3-hydroxyproline dehydratase D 4.2.1.78 (S)-norcoclaurine synthase D 4.2.1.79 2-methylcitrate dehydratase D 4.2.1.80 2-oxopent-4-enoate hydratase D 4.2.1.81 D(-)-tartrate dehydratase D 4.2.1.82 xylonate dehydratase D 4.2.1.83 4-oxalomesaconate hydratase D 4.2.1.84 nitrile hydratase D 4.2.1.85 dimethylmaleate hydratase D 4.2.1.87 octopamine dehydratase D 4.2.1.88 synephrine dehydratase D 4.2.1.90 L-rhamnonate dehydratase D 4.2.1.91 arogenate dehydratase E CH54_1657 bacterial extracellular solute-binding s, 3 family protein K01713 pheC; cyclohexadienyl dehydratase [EC:4.2.1.51 4.2.1.91] D 4.2.1.92 hydroperoxide dehydratase D 4.2.1.93 ATP-dependent NAD(P)H-hydrate dehydratase D 4.2.1.94 scytalone dehydratase D 4.2.1.95 kievitone hydratase D 4.2.1.96 4a-hydroxytetrahydrobiopterin dehydratase D 4.2.1.97 phaseollidin hydratase D 4.2.1.98 16alpha-hydroxyprogesterone dehydratase D 4.2.1.99 2-methylisocitrate dehydratase E CH54_1750 acnB; aconitate hydratase 2 K01682 acnB; aconitate hydratase 2 / 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99] D 4.2.1.100 cyclohexa-1,5-dienecarbonyl-CoA hydratase D 4.2.1.103 cyclohexyl-isocyanide hydratase D 4.2.1.104 cyanase D 4.2.1.105 2-hydroxyisoflavanone dehydratase D 4.2.1.106 bile-acid 7alpha-dehydratase D 4.2.1.107 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase D 4.2.1.108 ectoine synthase D 4.2.1.109 methylthioribulose 1-phosphate dehydratase E CH54_3574 mtnB; methylthioribulose-1-phosphate dehydratase K08964 mtnB; methylthioribulose-1-phosphate dehydratase [EC:4.2.1.109] D 4.2.1.110 aldos-2-ulose dehydratase D 4.2.1.111 1,5-anhydro-D-fructose dehydratase D 4.2.1.112 acetylene hydratase D 4.2.1.113 o-succinylbenzoate synthase E CH54_3954 menC; o-succinylbenzoate synthase K02549 menC; o-succinylbenzoate synthase [EC:4.2.1.113] D 4.2.1.114 methanogen homoaconitase D 4.2.1.115 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-inverting) E CH54_3603 3-beta hydroxysteroid dehydrogenase/isomerase family protein K15894 pseB; UDP-N-acetylglucosamine 4,6-dehydratase/5-epimerase [EC:4.2.1.115 5.1.3.-] D 4.2.1.116 3-hydroxypropionyl-CoA dehydratase D 4.2.1.117 2-methylcitrate dehydratase (2-methyl-trans-aconitate forming) D 4.2.1.118 3-dehydroshikimate dehydratase D 4.2.1.119 enoyl-CoA hydratase 2 D 4.2.1.120 4-hydroxybutanoyl-CoA dehydratase D 4.2.1.121 colneleate synthase D 4.2.1.122 tryptophan synthase (indole-salvaging) D 4.2.1.123 tetrahymanol synthase D 4.2.1.124 arabidiol synthase D 4.2.1.125 dammarenediol II synthase D 4.2.1.126 N-acetylmuramic acid 6-phosphate etherase E CH54_1489 murQ; N-acetylmuramic acid 6-phosphate etherase K07106 murQ; N-acetylmuramic acid 6-phosphate etherase [EC:4.2.1.126] E CH54_3096 murQ; N-acetylmuramic acid 6-phosphate etherase K07106 murQ; N-acetylmuramic acid 6-phosphate etherase [EC:4.2.1.126] D 4.2.1.127 linalool dehydratase D 4.2.1.128 lupan-3beta,20-diol synthase D 4.2.1.129 squalene---hopanol cyclase D 4.2.1.130 D-lactate dehydratase D 4.2.1.131 carotenoid 1,2-hydratase D 4.2.1.132 2-hydroxyhexa-2,4-dienoate hydratase D 4.2.1.133 copal-8-ol diphosphate hydratase D 4.2.1.134 very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase D 4.2.1.135 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining) E CH54_3739 3-beta hydroxysteroid dehydrogenase/isomerase family protein K24300 wbpM; UDP-N-acetylglucosamine 4,6-dehydratase [EC:4.2.1.135] D 4.2.1.136 ADP-dependent NAD(P)H-hydrate dehydratase E CH54_2043 yjeF-related family protein K23997 nnr; ADP-dependent NAD(P)H-hydrate dehydratase / NAD(P)H-hydrate epimerase [EC:4.2.1.136 5.1.99.6] D 4.2.1.137 sporulenol synthase D 4.2.1.138 (+)-caryolan-1-ol synthase D 4.2.1.139 pterocarpan synthase D 4.2.1.140 gluconate/galactonate dehydratase D 4.2.1.141 2-dehydro-3-deoxy-D-arabinonate dehydratase D 4.2.1.142 5'-oxoaverantin cyclase D 4.2.1.143 versicolorin B synthase D 4.2.1.144 3-amino-5-hydroxybenzoate synthase D 4.2.1.145 capreomycidine synthase D 4.2.1.146 L-galactonate dehydratase D 4.2.1.147 5,6,7,8-tetrahydromethanopterin hydro-lyase D 4.2.1.148 2-methylfumaryl-CoA hydratase D 4.2.1.149 crotonobetainyl-CoA hydratase D 4.2.1.150 short-chain-enoyl-CoA hydratase D 4.2.1.151 chorismate dehydratase D 4.2.1.152 hydroperoxy icosatetraenoate dehydratase D 4.2.1.153 3-methylfumaryl-CoA hydratase D 4.2.1.154 tetracenomycin F2 cyclase D 4.2.1.155 (methylthio)acryloyl-CoA hydratase D 4.2.1.156 L-talarate dehydratase D 4.2.1.157 (R)-2-hydroxyisocaproyl-CoA dehydratase D 4.2.1.158 galactarate dehydratase (D-threo-forming) D 4.2.1.159 dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose 2,3-dehydratase D 4.2.1.160 2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one isomerase/dehydratase D 4.2.1.161 bisanhydrobacterioruberin hydratase D 4.2.1.162 6-deoxy-6-sulfo-D-gluconate dehydratase D 4.2.1.163 2-oxo-hept-4-ene-1,7-dioate hydratase D 4.2.1.164 dTDP-4-dehydro-2,6-dideoxy-D-glucose 3-dehydratase D 4.2.1.165 chlorophyllide a 31-hydratase D 4.2.1.166 phosphinomethylmalate isomerase D 4.2.1.167 (R)-2-hydroxyglutaryl-CoA dehydratase D 4.2.1.168 GDP-4-dehydro-6-deoxy-alpha-D-mannose 3-dehydratase D 4.2.1.169 3-vinyl bacteriochlorophyllide d 31-hydratase D 4.2.1.170 2-(omega-methylthio)alkylmalate dehydratase D 4.2.1.171 cis-L-3-hydroxyproline dehydratase D 4.2.1.172 trans-4-hydroxy-L-proline dehydratase D 4.2.1.173 ent-8alpha-hydroxylabd-13-en-15-yl diphosphate synthase D 4.2.1.174 peregrinol diphosphate synthase D 4.2.1.175 (R)-3-(aryl)lactoyl-CoA dehydratase D 4.2.1.176 L-lyxonate dehydratase D 4.2.1.177 (2S)-3-sulfopropanediol dehydratase D 4.2.1.178 difructose-dianhydride-III synthase D 4.2.1.179 difructose-anhydride-I synthase D 4.2.1.180 (E)-benzylidenesuccinyl-CoA hydratase D 4.2.1.181 3-carboxymethyl-3-hydroxy-acyl-[acp] dehydratase D 4.2.1.182 phosphomevalonate dehydratase C 4.2.2 Acting on polysaccharides D 4.2.2.1 hyaluronate lyase D 4.2.2.2 pectate lyase E CH54_2402 periplasmic pectate lyase family protein K01728 pel; pectate lyase [EC:4.2.2.2] D 4.2.2.3 mannuronate-specific alginate lyase D 4.2.2.5 chondroitin AC lyase D 4.2.2.6 oligogalacturonide lyase E CH54_221 oligogalacturonate lyase family protein K01730 ogl; oligogalacturonide lyase [EC:4.2.2.6] D 4.2.2.7 heparin lyase D 4.2.2.8 heparin-sulfate lyase D 4.2.2.9 pectate disaccharide-lyase E CH54_231 periplasmic pectate lyase family protein K01731 pelW; pectate disaccharide-lyase [EC:4.2.2.9] D 4.2.2.10 pectin lyase D 4.2.2.11 guluronate-specific alginate lyase D 4.2.2.12 xanthan lyase D 4.2.2.13 exo-(1->4)-alpha-D-glucan lyase D 4.2.2.14 glucuronan lyase D 4.2.2.15 anhydrosialidase D 4.2.2.16 levan fructotransferase (DFA-IV-forming) D 4.2.2.17 inulin fructotransferase (DFA-I-forming) D 4.2.2.18 inulin fructotransferase (DFA-III-forming) D 4.2.2.19 chondroitin B lyase D 4.2.2.20 chondroitin-sulfate-ABC endolyase D 4.2.2.21 chondroitin-sulfate-ABC exolyase D 4.2.2.22 pectate trisaccharide-lyase D 4.2.2.23 rhamnogalacturonan endolyase D 4.2.2.24 rhamnogalacturonan exolyase D 4.2.2.25 gellan lyase D 4.2.2.26 oligo-alginate lyase D 4.2.2.27 pectin monosaccharide-lyase D 4.2.2.28 alpha-L-rhamnosyl-(1->4)-beta-D-glucuronate lyase D 4.2.2.29 peptidoglycan lytic transglycosylase E CH54_1216 rlpA; rare lipoA family protein K03642 rlpA; peptidoglycan lytic transglycosylase [EC:4.2.2.29] E CH54_82 yceG-like family protein K07082 mltG; peptidoglycan lytic transglycosylase G [EC:4.2.2.29] E CH54_3501 mltA specific insert domain protein K08304 mltA; peptidoglycan lytic transglycosylase A [EC:4.2.2.29] E CH54_597 lytic murein transglycosylase family protein K08305 mltB; peptidoglycan lytic transglycosylase B [EC:4.2.2.29] E CH54_1250 mltB; lytic murein transglycosylase B K08305 mltB; peptidoglycan lytic transglycosylase B [EC:4.2.2.29] E CH54_3359 hypothetical protein K08306 mltC; peptidoglycan lytic transglycosylase C [EC:4.2.2.29] E CH54_1589 lysM domain protein K08307 mltD; peptidoglycan lytic transglycosylase D [EC:4.2.2.29] E CH54_242 transglycosylase SLT domain protein K08308 mltE; peptidoglycan lytic transglycosylase E [EC:4.2.2.29] E CH54_1855 soluble lytic murein transglycosylase L domain protein K08309 slt; peptidoglycan lytic transglycosylase [EC:4.2.2.29] E CH54_1485 bacterial extracellular solute-binding s, 3 family protein K18691 mltF; peptidoglycan lytic transglycosylase F [EC:4.2.2.29] C 4.2.3 Acting on phosphates D 4.2.3.1 threonine synthase E CH54_1846 thrC; threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1] D 4.2.3.2 ethanolamine-phosphate phospho-lyase D 4.2.3.3 methylglyoxal synthase E CH54_19 mgsA; methylglyoxal synthase K01734 mgsA; methylglyoxal synthase [EC:4.2.3.3] D 4.2.3.4 3-dehydroquinate synthase E CH54_2305 aroB; 3-dehydroquinate synthase K01735 aroB; 3-dehydroquinate synthase [EC:4.2.3.4] D 4.2.3.5 chorismate synthase E CH54_3863 aroC; chorismate synthase K01736 aroC; chorismate synthase [EC:4.2.3.5] D 4.2.3.6 trichodiene synthase D 4.2.3.7 pentalenene synthase D 4.2.3.8 casbene synthase D 4.2.3.9 aristolochene synthase D 4.2.3.10 (-)-endo-fenchol synthase D 4.2.3.11 sabinene-hydrate synthase D 4.2.3.12 6-pyruvoyltetrahydropterin synthase E CH54_1700 queD; queuosine biosynthesis protein QueD K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50] D 4.2.3.13 (+)-delta-cadinene synthase D 4.2.3.15 myrcene synthase D 4.2.3.16 (4S)-limonene synthase D 4.2.3.17 taxadiene synthase D 4.2.3.18 abieta-7,13-diene synthase D 4.2.3.19 ent-kaurene synthase D 4.2.3.20 (R)-limonene synthase D 4.2.3.21 vetispiradiene synthase D 4.2.3.22 germacradienol synthase D 4.2.3.23 germacrene-A synthase D 4.2.3.24 amorpha-4,11-diene synthase D 4.2.3.25 S-linalool synthase D 4.2.3.26 R-linalool synthase D 4.2.3.27 isoprene synthase D 4.2.3.28 ent-cassa-12,15-diene synthase D 4.2.3.29 ent-sandaracopimaradiene synthase D 4.2.3.30 ent-pimara-8(14),15-diene synthase D 4.2.3.31 ent-pimara-9(11),15-diene synthase D 4.2.3.32 levopimaradiene synthase D 4.2.3.33 stemar-13-ene synthase D 4.2.3.34 stemod-13(17)-ene synthase D 4.2.3.35 syn-pimara-7,15-diene synthase D 4.2.3.36 terpentetriene synthase D 4.2.3.37 epi-isozizaene synthase D 4.2.3.38 alpha-bisabolene synthase D 4.2.3.39 epi-cedrol synthase D 4.2.3.40 (Z)-gamma-bisabolene synthase D 4.2.3.41 elisabethatriene synthase D 4.2.3.42 aphidicolan-16beta-ol synthase D 4.2.3.43 fusicocca-2,10(14)-diene synthase D 4.2.3.44 isopimara-7,15-diene synthase D 4.2.3.45 phyllocladan-16alpha-ol synthase D 4.2.3.46 alpha-farnesene synthase D 4.2.3.47 beta-farnesene synthase D 4.2.3.48 (3S,6E)-nerolidol synthase D 4.2.3.49 (3R,6E)-nerolidol synthase D 4.2.3.50 (+)-alpha-santalene synthase [(2Z,6Z)-farnesyl diphosphate cyclizing] D 4.2.3.51 beta-phellandrene synthase (neryl-diphosphate-cyclizing) D 4.2.3.52 (4S)-beta-phellandrene synthase (geranyl-diphosphate-cyclizing) D 4.2.3.53 (+)-endo-beta-bergamotene synthase [(2Z,6Z)-farnesyl diphosphate cyclizing] D 4.2.3.54 (-)-endo-alpha-bergamotene synthase [(2Z,6Z)-farnesyl diphosphate cyclizing] D 4.2.3.55 (S)-beta-bisabolene synthase D 4.2.3.56 gamma-humulene synthase D 4.2.3.57 (-)-beta-caryophyllene synthase D 4.2.3.58 longifolene synthase D 4.2.3.59 (E)-gamma-bisabolene synthase D 4.2.3.60 germacrene C synthase D 4.2.3.61 5-epiaristolochene synthase D 4.2.3.62 (-)-gamma-cadinene synthase [(2Z,6E)-farnesyl diphosphate cyclizing] D 4.2.3.63 (+)-cubenene synthase D 4.2.3.64 (+)-epicubenol synthase D 4.2.3.65 zingiberene synthase D 4.2.3.66 beta-selinene cyclase D 4.2.3.67 cis-muuroladiene synthase D 4.2.3.68 beta-eudesmol synthase D 4.2.3.69 (+)-alpha-barbatene synthase D 4.2.3.70 patchoulol synthase D 4.2.3.71 (E,E)-germacrene B synthase D 4.2.3.72 alpha-gurjunene synthase D 4.2.3.73 valencene synthase D 4.2.3.74 presilphiperfolanol synthase D 4.2.3.75 (-)-germacrene D synthase D 4.2.3.76 (+)-delta-selinene synthase D 4.2.3.77 (+)-germacrene D synthase D 4.2.3.78 beta-chamigrene synthase D 4.2.3.79 thujopsene synthase D 4.2.3.80 alpha-longipinene synthase D 4.2.3.81 exo-alpha-bergamotene synthase D 4.2.3.82 alpha-santalene synthase D 4.2.3.83 beta-santalene synthase D 4.2.3.84 10-epi-gamma-eudesmol synthase D 4.2.3.85 alpha-eudesmol synthase D 4.2.3.86 7-epi-alpha-selinene synthase D 4.2.3.87 alpha-guaiene synthase D 4.2.3.88 viridiflorene synthase D 4.2.3.89 (+)-beta-caryophyllene synthase D 4.2.3.90 5-epi-alpha-selinene synthase D 4.2.3.91 cubebol synthase D 4.2.3.92 (+)-gamma-cadinene synthase D 4.2.3.93 delta-guaiene synthase D 4.2.3.94 gamma-curcumene synthase D 4.2.3.95 (-)-alpha-cuprenene synthase D 4.2.3.96 avermitilol synthase D 4.2.3.97 (-)-delta-cadinene synthase D 4.2.3.98 (+)-T-muurolol synthase D 4.2.3.99 labdatriene synthase D 4.2.3.100 bicyclogermacrene synthase D 4.2.3.101 7-epi-sesquithujene synthase D 4.2.3.102 sesquithujene synthase D 4.2.3.103 ent-isokaurene synthase D 4.2.3.104 alpha-humulene synthase D 4.2.3.105 tricyclene synthase D 4.2.3.106 (E)-beta-ocimene synthase D 4.2.3.107 (+)-car-3-ene synthase D 4.2.3.108 1,8-cineole synthase D 4.2.3.109 (-)-sabinene synthase D 4.2.3.110 (+)-sabinene synthase D 4.2.3.111 (-)-alpha-terpineol synthase D 4.2.3.112 (+)-alpha-terpineol synthase D 4.2.3.113 terpinolene synthase D 4.2.3.114 gamma-terpinene synthase D 4.2.3.115 alpha-terpinene synthase D 4.2.3.116 (+)-camphene synthase D 4.2.3.117 (-)-camphene synthase D 4.2.3.118 2-methylisoborneol synthase D 4.2.3.119 (-)-alpha-pinene synthase D 4.2.3.120 (-)-beta-pinene synthase D 4.2.3.121 (+)-alpha-pinene synthase D 4.2.3.122 (+)-beta-pinene synthase D 4.2.3.123 beta-sesquiphellandrene synthase D 4.2.3.124 2-deoxy-scyllo-inosose synthase D 4.2.3.125 alpha-muurolene synthase D 4.2.3.126 gamma-muurolene synthase D 4.2.3.127 beta-copaene synthase D 4.2.3.128 beta-cubebene synthase D 4.2.3.129 (+)-sativene synthase D 4.2.3.130 tetraprenyl-beta-curcumene synthase D 4.2.3.131 miltiradiene synthase D 4.2.3.132 neoabietadiene synthase D 4.2.3.133 alpha-copaene synthase D 4.2.3.134 5-phosphooxy-L-lysine phospho-lyase D 4.2.3.135 Delta6-protoilludene synthase D 4.2.3.136 alpha-isocomene synthase D 4.2.3.137 (E)-2-epi-beta-caryophyllene synthase D 4.2.3.138 (+)-epi-alpha-bisabolol synthase D 4.2.3.139 valerena-4,7(11)-diene synthase D 4.2.3.140 cis-abienol synthase D 4.2.3.141 sclareol synthase D 4.2.3.142 7-epizingiberene synthase [(2Z,6Z)-farnesyl diphosphate cyclizing] D 4.2.3.143 kunzeaol synthase D 4.2.3.144 geranyllinalool synthase D 4.2.3.145 ophiobolin F synthase D 4.2.3.146 cyclooctat-9-en-7-ol synthase D 4.2.3.147 pimaradiene synthase D 4.2.3.148 cembrene C synthase D 4.2.3.149 nephthenol synthase D 4.2.3.150 cembrene A synthase D 4.2.3.151 pentamethylcyclopentadecatrienol synthase D 4.2.3.152 2-epi-5-epi-valiolone synthase D 4.2.3.153 (5-formylfuran-3-yl)methyl phosphate synthase D 4.2.3.154 demethyl-4-deoxygadusol synthase D 4.2.3.155 2-epi-valiolone synthase D 4.2.3.156 hydroxysqualene synthase D 4.2.3.157 (+)-isoafricanol synthase D 4.2.3.158 (-)-spiroviolene synthase D 4.2.3.159 tsukubadiene synthase D 4.2.3.160 (2S,3R,6S,9S)-(-)-protoillud-7-ene synthase D 4.2.3.161 (3S)-(+)-asterisca-2(9),6-diene synthase D 4.2.3.162 (-)-alpha-amorphene synthase D 4.2.3.163 (+)-corvol ether B synthase D 4.2.3.164 (+)-eremophilene synthase D 4.2.3.165 (1R,4R,5S)-(-)-guaia-6,10(14)-diene synthase D 4.2.3.166 (+)-(1E,4E,6S,7R)-germacra-1(10),4-dien-6-ol synthase D 4.2.3.167 dolabella-3,7-dien-18-ol synthase D 4.2.3.168 dolathalia-3,7,11-triene synthase D 4.2.3.169 7-epi-alpha-eudesmol synthase D 4.2.3.170 4-epi-cubebol synthase D 4.2.3.171 (+)-corvol ether A synthase D 4.2.3.172 10-epi-juneol synthase D 4.2.3.173 tau-cadinol synthase D 4.2.3.174 (2E,6E)-hedycaryol synthase D 4.2.3.175 10-epi-cubebol synthase D 4.2.3.176 sesterfisherol synthase D 4.2.3.177 beta-thujene synthase D 4.2.3.178 stellata-2,6,19-triene synthase D 4.2.3.179 guaia-4,6-diene synthase D 4.2.3.180 pseudolaratriene synthase D 4.2.3.181 selina-4(15),7(11)-diene synthase D 4.2.3.182 pristinol synthase D 4.2.3.183 nezukol synthase D 4.2.3.184 5-hydroxy-alpha-gurjunene synthase D 4.2.3.185 ent-atiserene synthase D 4.2.3.186 ent-13-epi-manoyl oxide synthase D 4.2.3.187 (2Z,6E)-hedycaryol synthase D 4.2.3.188 beta-geranylfarnesene synthase D 4.2.3.189 9,13-epoxylabd-14-ene synthase D 4.2.3.190 manoyl oxide synthase D 4.2.3.191 cycloaraneosene synthase D 4.2.3.192 labda-7,13(16),14-triene synthase D 4.2.3.193 (12E)-labda-8(17),12,14-triene synthase D 4.2.3.194 (-)-drimenol synthase D 4.2.3.195 rhizathalene A synthase D 4.2.3.196 dolabradiene synthase D 4.2.3.197 eudesmane-5,11-diol synthase D 4.2.3.198 alpha-selinene synthase D 4.2.3.199 (-)-5-epieremophilene synthase D 4.2.3.200 beta-pinacene synthase D 4.2.3.201 hydropyrene synthase D 4.2.3.202 hydropyrenol synthase D 4.2.3.203 isoelisabethatriene synthase D 4.2.3.204 valerianol synthase D 4.2.3.205 sodorifen synthase D 4.2.3.206 (-)-cyatha-3,12-diene synthase D 4.2.3.207 neoverrucosan-5beta-ol synthase D 4.2.3.208 verrucosan-2beta-ol synthase D 4.2.3.209 (R)-axinyssene synthase D 4.2.3.210 lydicene synthase D 4.2.3.211 (+)-exo-beta-bergamotene synthase D 4.2.3.212 (+)-delta-cadinol synthase D 4.2.3.213 colleterpenol synthase D 4.2.3.214 dolasta-1(15),8-diene synthase D 4.2.3.215 delta-araneosene synthase D 4.2.3.216 somaliensene A synthase D 4.2.3.217 somaliensene B synthase D 4.2.3.218 variediene synthase D 4.2.3.219 (2E)-alpha-cericerene synthase C 4.2.99 Other carbon-oxygen lyases D 4.2.99.12 carboxymethyloxysuccinate lyase D 4.2.99.18 DNA-(apurinic or apyrimidinic site) lyase E CH54_2648 mutM; DNA-formamidopyrimidine glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] E CH54_471 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D 4.2.99.20 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase E CH54_3952 menH; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase K08680 menH; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase [EC:4.2.99.20] D 4.2.99.21 isochorismate lyase E CH54_882 salicylate synthase K04781 mbtI; salicylate synthetase [EC:5.4.4.2 4.2.99.21] D 4.2.99.22 tuliposide A-converting enzyme D 4.2.99.23 tuliposide B-converting enzyme D 4.2.99.24 thebaine synthase D 4.2.99.25 unsaturated pyranuronate lyase E CH54_234 cupin domain protein K26933 kdgF; unsaturated pyranuronate lyase [EC:4.2.99.25] B 4.3 Carbon-nitrogen lyases C 4.3.1 Ammonia-lyases D 4.3.1.1 aspartate ammonia-lyase E CH54_2066 aspA; aspartate ammonia-lyase K01744 aspA; aspartate ammonia-lyase [EC:4.3.1.1] D 4.3.1.2 methylaspartate ammonia-lyase D 4.3.1.3 histidine ammonia-lyase E CH54_2432 hutH; histidine ammonia-lyase K01745 hutH; histidine ammonia-lyase [EC:4.3.1.3] D 4.3.1.4 formimidoyltetrahydrofolate cyclodeaminase D 4.3.1.6 beta-alanyl-CoA ammonia-lyase D 4.3.1.7 ethanolamine ammonia-lyase D 4.3.1.9 glucosaminate ammonia-lyase D 4.3.1.10 serine-sulfate ammonia-lyase D 4.3.1.12 ornithine cyclodeaminase D 4.3.1.13 carbamoyl-serine ammonia-lyase D 4.3.1.14 3-aminobutyryl-CoA ammonia-lyase D 4.3.1.15 diaminopropionate ammonia-lyase D 4.3.1.16 threo-3-hydroxy-L-aspartate ammonia-lyase E CH54_3595 pyridoxal-phosphate dependent enzyme family protein K22589 thadh; threo-3-hydroxy-L-aspartate ammonia-lyase [EC:4.3.1.16] D 4.3.1.17 L-serine ammonia-lyase E CH54_4036 L-serine ammonia-lyase K01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17] E CH54_166 L-serine ammonia-lyase K01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17] D 4.3.1.18 D-serine ammonia-lyase D 4.3.1.19 threonine ammonia-lyase E CH54_2490 pyridoxal-phosphate dependent enzyme family protein K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19] E CH54_2731 ilvA; threonine ammonia-lyase, biosynthetic K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19] D 4.3.1.20 erythro-3-hydroxy-L-aspartate ammonia-lyase D 4.3.1.22 3,4-dihydroxyphenylalanine reductive deaminase D 4.3.1.23 tyrosine ammonia-lyase D 4.3.1.24 phenylalanine ammonia-lyase D 4.3.1.25 phenylalanine/tyrosine ammonia-lyase D 4.3.1.27 threo-3-hydroxy-D-aspartate ammonia-lyase D 4.3.1.28 L-lysine cyclodeaminase D 4.3.1.29 D-glucosaminate-6-phosphate ammonia-lyase D 4.3.1.30 dTDP-4-amino-4,6-dideoxy-D-glucose ammonia-lyase D 4.3.1.31 L-tryptophan ammonia lyase D 4.3.1.32 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase D 4.3.1.33 (R)-1-hydroxy-2-aminoethylphosphonate ammonia-lyase C 4.3.2 Amidine-lyases D 4.3.2.1 argininosuccinate lyase E CH54_2699 argH; argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1] D 4.3.2.2 adenylosuccinate lyase E CH54_114 purB; adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2] D 4.3.2.3 ureidoglycolate lyase D 4.3.2.4 purine imidazole-ring cyclase D 4.3.2.5 peptidylamidoglycolate lyase D 4.3.2.6 gamma-L-glutamyl-butirosin B gamma-glutamyl cyclotransferase D 4.3.2.7 glutathione-specific gamma-glutamylcyclotransferase D 4.3.2.8 gamma-glutamylamine cyclotransferase D 4.3.2.9 gamma-glutamylcyclotransferase D 4.3.2.10 imidazole glycerol-phosphate synthase E CH54_984 hisF; imidazoleglycerol phosphate synthase, cyclase subunit K02500 hisF; imidazole glycerol-phosphate synthase subunit HisF [EC:4.3.2.10] E CH54_982 hisH; imidazole glycerol phosphate synthase, glutamine amidotransferase subunit K02501 hisH; imidazole glycerol-phosphate synthase subunit HisH [EC:4.3.2.10] D 4.3.2.11 (3R)-3-[(carboxylmethyl)amino]fatty acid synthase C 4.3.3 Amine-lyases D 4.3.3.1 3-ketovalidoxylamine C-N-lyase D 4.3.3.2 strictosidine synthase D 4.3.3.3 deacetylisoipecoside synthase D 4.3.3.4 deacetylipecoside synthase D 4.3.3.5 4'-demethylrebeccamycin synthase D 4.3.3.6 pyridoxal 5'-phosphate synthase (glutamine hydrolysing) D 4.3.3.7 4-hydroxy-tetrahydrodipicolinate synthase E CH54_1345 dapA; 4-hydroxy-tetrahydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7] D 4.3.3.8 mimosinase C 4.3.99 Other carbon-nitrogen lyases D 4.3.99.3 7-carboxy-7-deazaguanine synthase E CH54_1701 putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3] D 4.3.99.4 choline trimethylamine-lyase D 4.3.99.5 nitrosuccinate lyase B 4.4 Carbon-sulfur lyases C 4.4.1 Carbon-sulfur lyases (only sub-subclass identified to date) D 4.4.1.1 cystathionine gamma-lyase E CH54_4033 cys/Met metabolism PLP-dependent enzyme family protein K01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1] D 4.4.1.2 homocysteine desulfhydrase D 4.4.1.3 dimethylpropiothetin dethiomethylase D 4.4.1.4 alliin lyase D 4.4.1.5 lactoylglutathione lyase E CH54_306 gloA; lactoylglutathione lyase K01759 GLO1; lactoylglutathione lyase [EC:4.4.1.5] D 4.4.1.9 L-3-cyanoalanine synthase D 4.4.1.10 cysteine lyase D 4.4.1.11 methionine gamma-lyase D 4.4.1.13 cysteine-S-conjugate beta-lyase E CH54_3138 metC; cystathionine beta-lyase K01760 metC; cysteine-S-conjugate beta-lyase [EC:4.4.1.13] E CH54_448 C-S lyase family protein K14155 patB; cysteine-S-conjugate beta-lyase [EC:4.4.1.13] D 4.4.1.14 1-aminocyclopropane-1-carboxylate synthase D 4.4.1.15 D-cysteine desulfhydrase E CH54_761 pyridoxal phosphate-dependent enzyme, D-cysteine desulfhydrase family protein K05396 dcyD; D-cysteine desulfhydrase [EC:4.4.1.15] D 4.4.1.16 selenocysteine lyase E CH54_287 sufS; cysteine desulfurase, SufS family protein K11717 sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16] D 4.4.1.17 holocytochrome-c synthase D 4.4.1.19 phosphosulfolactate synthase D 4.4.1.20 leukotriene-C4 synthase D 4.4.1.21 S-ribosylhomocysteine lyase E CH54_1618 S-Ribosylhomocysteinase family protein K07173 luxS; S-ribosylhomocysteine lyase [EC:4.4.1.21] D 4.4.1.22 S-(hydroxymethyl)glutathione synthase D 4.4.1.23 2-hydroxypropyl-CoM lyase D 4.4.1.24 (2R)-sulfolactate sulfo-lyase D 4.4.1.25 L-cysteate sulfo-lyase D 4.4.1.26 olivetolic acid cyclase D 4.4.1.28 L-cysteine desulfidase D 4.4.1.29 phycobiliprotein cysteine-84 phycobilin lyase D 4.4.1.30 phycobiliprotein beta-cysteine-155 phycobilin lyase D 4.4.1.31 phycoerythrocyanin alpha-cysteine-84 phycoviolobilin lyase/isomerase D 4.4.1.32 C-phycocyanin alpha-cysteine-84 phycocyanobilin lyase D 4.4.1.33 R-phycocyanin alpha-cysteine-84 phycourobilin lyase/isomerase D 4.4.1.34 isoprene-epoxide---glutathione S-transferase D 4.4.1.35 L-cystine beta-lyase D 4.4.1.36 hercynylcysteine S-oxide lyase D 4.4.1.37 pyridinium-3,5-bisthiocarboxylic acid mononucleotide synthase D 4.4.1.38 isethionate sulfite-lyase D 4.4.1.39 C-phycoerythrin alpha-cysteine-82 phycoerythrobilin lyase D 4.4.1.40 C-phycoerythrin beta-cysteine-48/59 phycoerythrobilin lyase D 4.4.1.41 (2S)-3-sulfopropanediol sulfolyase D 4.4.1.42 S-adenosyl-L-methionine lyase D 4.4.1.43 canavanine-gamma-lyase B 4.5 Carbon-halide lyases C 4.5.1 Carbon-halide lyases (only sub-subclass identified to date) D 4.5.1.1 DDT-dehydrochlorinase D 4.5.1.2 3-chloro-D-alanine dehydrochlorinase D 4.5.1.3 dichloromethane dehalogenase D 4.5.1.4 L-2-amino-4-chloropent-4-enoate dehydrochlorinase D 4.5.1.5 S-carboxymethylcysteine synthase B 4.6 Phosphorus-oxygen lyases C 4.6.1 Phosphorus-oxygen lyases (only sub-subclass identified to date) D 4.6.1.1 adenylate cyclase E CH54_2773 adenylate cyclase, class-I family protein K05851 cyaA; adenylate cyclase, class 1 [EC:4.6.1.1] E CH54_1082 CYTH domain protein K05873 cyaB; adenylate cyclase, class 2 [EC:4.6.1.1] D 4.6.1.2 guanylate cyclase D 4.6.1.6 cytidylate cyclase D 4.6.1.12 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase E CH54_1685 ispF; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase K01770 ispF; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [EC:4.6.1.12] D 4.6.1.13 phosphatidylinositol diacylglycerol-lyase E CH54_355 phosphatidylinositol-specific phospholipase C, X domain protein K01771 plc; 1-phosphatidylinositol phosphodiesterase [EC:4.6.1.13] D 4.6.1.14 glycosylphosphatidylinositol diacylglycerol-lyase D 4.6.1.15 FAD-AMP lyase (cyclizing) D 4.6.1.16 tRNA-intron lyase D 4.6.1.17 cyclic pyranopterin monophosphate synthase E CH54_1098 moaC; molybdenum cofactor biosynthesis protein C K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17] D 4.6.1.18 pancreatic ribonuclease D 4.6.1.19 ribonuclease T2 D 4.6.1.20 ribonuclease U2 D 4.6.1.21 Enterobacter ribonuclease D 4.6.1.22 Bacillus subtilis ribonuclease D 4.6.1.23 ribotoxin D 4.6.1.24 ribonuclease T1 D 4.6.1.25 bacteriophage T4 restriction endoribonuclease RegB D 4.6.1.26 uridylate cyclase B 4.7 carbon-phosphorus lyases C 4.7.1 carbon-phosphorus lyases (only sub-subclass identified to date) D 4.7.1.1 alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase E CH54_1949 phosphonate metabolism PhnJ family protein K06163 phnJ; alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase [EC:4.7.1.1] B 4.8 Nitrogen-oxygen lyases C 4.8.1 Hydro-lyases D 4.8.1.1 L-piperazate synthase D 4.8.1.2 aliphatic aldoxime dehydratase D 4.8.1.3 indoleacetaldoxime dehydratase D 4.8.1.4 phenylacetaldoxime dehydratase D 4.8.1.5 thiohydroximate-O-sulfate sulfate/sulfur-lyase (nitrile-forming) D 4.8.1.6 N-(sulfonatooxy)alkenimidothioic acid sulfate-lyase (epithionitrile-forming) D 4.8.1.7 phenyl-N-(sulfonatooxy)methanimidothioate sulfolyase D 4.8.1.8 N-(sulfonatooxy)prop-2-enimidothioate sulfolyase B 4.98 ATP-independent chelatases C 4.98.1 Forming coordination complexes D 4.98.1.1 protoporphyrin ferrochelatase E CH54_3732 hemH; ferrochelatase K01772 hemH; protoporphyrin/coproporphyrin ferrochelatase [EC:4.98.1.1 4.99.1.9] B 4.99 Other lyases C 4.99.1 Sole sub-subclass for lyases that do not belong in the other subclasses D 4.99.1.2 alkylmercury lyase D 4.99.1.3 sirohydrochlorin cobaltochelatase E CH54_927 cbiX family protein K02190 cbiK; sirohydrochlorin cobaltochelatase [EC:4.99.1.3] D 4.99.1.4 sirohydrochlorin ferrochelatase E CH54_1695 cobA; uroporphyrinogen-III C-methyltransferase K02302 cysG; uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4] E CH54_2299 cobA; uroporphyrinogen-III C-methyltransferase K02302 cysG; uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4] D 4.99.1.8 heme ligase D 4.99.1.9 coproporphyrin ferrochelatase E CH54_3732 hemH; ferrochelatase K01772 hemH; protoporphyrin/coproporphyrin ferrochelatase [EC:4.98.1.1 4.99.1.9] D 4.99.1.10 magnesium dechelatase D 4.99.1.11 sirohydrochlorin nickelchelatase D 4.99.1.12 pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel chelatase # A5. Isomerases B 5.1 Racemases and epimerases C 5.1.1 Acting on amino acids and derivatives D 5.1.1.1 alanine racemase E CH54_587 alr; alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1] E CH54_2936 alr; alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1] D 5.1.1.2 methionine racemase D 5.1.1.3 glutamate racemase E CH54_2716 murI; glutamate racemase K01776 murI; glutamate racemase [EC:5.1.1.3] D 5.1.1.4 proline racemase D 5.1.1.5 lysine racemase D 5.1.1.6 threonine racemase D 5.1.1.7 diaminopimelate epimerase E CH54_2776 dapF; diaminopimelate epimerase K01778 dapF; diaminopimelate epimerase [EC:5.1.1.7] D 5.1.1.8 4-hydroxyproline epimerase D 5.1.1.9 arginine racemase D 5.1.1.10 amino-acid racemase E CH54_3871 aspartate racemase family protein K25316 racX; amino-acid racemase [EC:5.1.1.10] D 5.1.1.11 phenylalanine racemase (ATP-hydrolysing) D 5.1.1.12 ornithine racemase D 5.1.1.13 aspartate racemase D 5.1.1.14 nocardicin A epimerase D 5.1.1.15 2-aminohexano-6-lactam racemase D 5.1.1.16 protein-serine epimerase D 5.1.1.17 isopenicillin-N epimerase D 5.1.1.18 serine racemase D 5.1.1.19 O-ureido-serine racemase D 5.1.1.20 L-Ala-D/L-Glu epimerase E CH54_350 hypothetical protein K19802 ycjG; L-Ala-D/L-Glu epimerase / N-acetyl-D-glutamate racemase [EC:5.1.1.20 5.1.1.25] D 5.1.1.21 isoleucine 2-epimerase D 5.1.1.22 4-hydroxyproline betaine 2-epimerase D 5.1.1.23 UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate epimerase D 5.1.1.24 histidine racemase D 5.1.1.25 N-acetyl-D-glutamate racemase E CH54_350 hypothetical protein K19802 ycjG; L-Ala-D/L-Glu epimerase / N-acetyl-D-glutamate racemase [EC:5.1.1.20 5.1.1.25] C 5.1.2 Acting on hydroxy acids and derivatives D 5.1.2.1 lactate racemase D 5.1.2.2 mandelate racemase D 5.1.2.3 3-hydroxybutyryl-CoA epimerase E CH54_3859 fadJ; fatty oxidation complex, alpha subunit FadJ K01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3] E CH54_2852 fadB; fatty oxidation complex, alpha subunit FadB K01825 fadB; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase [EC:1.1.1.35 4.2.1.17 5.1.2.3 5.3.3.8] D 5.1.2.4 acetoin racemase D 5.1.2.5 tartrate epimerase D 5.1.2.6 isocitrate epimerase D 5.1.2.7 tagaturonate epimerase C 5.1.3 Acting on carbohydrates and derivatives D 5.1.3.1 ribulose-phosphate 3-epimerase E CH54_2302 rpe; ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1] D 5.1.3.2 UDP-glucose 4-epimerase E CH54_1118 galE; UDP-glucose 4-epimerase GalE K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] E CH54_3741 galE; UDP-glucose 4-epimerase GalE K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2] D 5.1.3.3 aldose 1-epimerase E CH54_1121 galM; galactose mutarotase K01785 galM; aldose 1-epimerase [EC:5.1.3.3] D 5.1.3.4 L-ribulose-5-phosphate 4-epimerase E CH54_483 araD; L-ribulose-5-phosphate 4-epimerase K03077 araD; L-ribulose-5-phosphate 4-epimerase [EC:5.1.3.4] D 5.1.3.5 UDP-arabinose 4-epimerase D 5.1.3.6 UDP-glucuronate 4-epimerase D 5.1.3.7 UDP-N-acetylglucosamine 4-epimerase D 5.1.3.8 N-acylglucosamine 2-epimerase D 5.1.3.9 N-acylglucosamine-6-phosphate 2-epimerase E CH54_1309 N-acetylmannosamine-6-phosphate epimerase family protein K01788 nanE; N-acylglucosamine-6-phosphate 2-epimerase [EC:5.1.3.9] D 5.1.3.10 CDP-paratose 2-epimerase D 5.1.3.11 cellobiose epimerase D 5.1.3.13 dTDP-4-dehydrorhamnose 3,5-epimerase D 5.1.3.14 UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) E CH54_2752 UDP-N-acetylglucosamine 2-epimerase K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14] D 5.1.3.15 glucose-6-phosphate 1-epimerase E CH54_578 aldose 1-epimerase family protein K01792 E5.1.3.15; glucose-6-phosphate 1-epimerase [EC:5.1.3.15] D 5.1.3.16 UDP-glucosamine 4-epimerase D 5.1.3.17 heparosan-N-sulfate-glucuronate 5-epimerase D 5.1.3.18 GDP-mannose 3,5-epimerase D 5.1.3.19 chondroitin-glucuronate 5-epimerase D 5.1.3.20 ADP-glyceromanno-heptose 6-epimerase E CH54_2654 rfaD; ADP-glyceromanno-heptose 6-epimerase K03274 gmhD; ADP-L-glycero-D-manno-heptose 6-epimerase [EC:5.1.3.20] D 5.1.3.21 maltose epimerase D 5.1.3.22 L-ribulose-5-phosphate 3-epimerase D 5.1.3.23 UDP-2,3-diacetamido-2,3-dideoxyglucuronic acid 2-epimerase D 5.1.3.24 N-acetylneuraminate epimerase E CH54_744 mutarotase, YjhT family protein K17948 nanM; N-acetylneuraminate epimerase [EC:5.1.3.24] D 5.1.3.25 dTDP-L-rhamnose 4-epimerase D 5.1.3.26 N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol 4-epimerase D 5.1.3.27 dTDP-4-dehydro-6-deoxy-D-glucose 3-epimerase D 5.1.3.28 UDP-N-acetyl-L-fucosamine synthase E CH54_3601 UDP-N-acetylglucosamine 2-epimerase K24258 wbjD; UDP-N-acetyl-L-fucosamine synthase [EC:5.1.3.28] D 5.1.3.29 L-fucose mutarotase D 5.1.3.30 D-psicose 3-epimerase D 5.1.3.31 D-tagatose 3-epimerase D 5.1.3.32 L-rhamnose mutarotase D 5.1.3.33 2-epi-5-epi-valiolone epimerase D 5.1.3.34 monoglucosyldiacylglycerol epimerase D 5.1.3.35 2-epi-5-epi-valiolone 7-phosphate 2-epimerase D 5.1.3.36 heparosan-glucuronate 5-epimerase D 5.1.3.37 mannuronan 5-epimerase D 5.1.3.38 D-erythrulose 1-phosphate 3-epimerase D 5.1.3.40 D-tagatose 6-phosphate 4-epimerase D 5.1.3.41 fructoselysine 3-epimerase D 5.1.3.42 D-glucosamine-6-phosphate 4-epimerase D 5.1.3.43 sulfoquinovose mutarotase D 5.1.3.44 mannose 2-epimerase C 5.1.99 Acting on other compounds D 5.1.99.1 methylmalonyl-CoA epimerase D 5.1.99.2 16-hydroxysteroid epimerase D 5.1.99.3 allantoin racemase D 5.1.99.4 alpha-methylacyl-CoA racemase D 5.1.99.5 hydantoin racemase D 5.1.99.6 NAD(P)H-hydrate epimerase E CH54_2043 yjeF-related family protein K23997 nnr; ADP-dependent NAD(P)H-hydrate dehydratase / NAD(P)H-hydrate epimerase [EC:4.2.1.136 5.1.99.6] D 5.1.99.7 dihydroneopterin triphosphate 2'-epimerase D 5.1.99.8 7,8-dihydroneopterin epimerase E CH54_3108 folB; dihydroneopterin aldolase K01633 folB; 7,8-dihydroneopterin aldolase/epimerase/oxygenase [EC:4.1.2.25 5.1.99.8 1.13.11.81] B 5.2 cis-trans-Isomerases C 5.2.1 cis-trans Isomerases (only sub-subclass identified to date) D 5.2.1.1 maleate isomerase D 5.2.1.2 maleylacetoacetate isomerase D 5.2.1.4 maleylpyruvate isomerase D 5.2.1.5 linoleate isomerase D 5.2.1.6 furylfuramide isomerase D 5.2.1.8 peptidylprolyl isomerase E CH54_2290 cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD family protein K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8] E CH54_3760 cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD family protein K03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8] E CH54_2744 PPIC-type PPIASE domain protein K03769 ppiC; peptidyl-prolyl cis-trans isomerase C [EC:5.2.1.8] E CH54_3691 PPIC-type PPIASE domain protein K03770 ppiD; peptidyl-prolyl cis-trans isomerase D [EC:5.2.1.8] E CH54_1815 PPIC-type PPIASE domain protein K03771 surA; peptidyl-prolyl cis-trans isomerase SurA [EC:5.2.1.8] E CH54_2265 domain amino terminal to FKBP-type peptidyl-prolyl isomerase family protein K03772 fkpA; FKBP-type peptidyl-prolyl cis-trans isomerase FkpA [EC:5.2.1.8] E CH54_2019 domain amino terminal to FKBP-type peptidyl-prolyl isomerase family protein K03773 fklB; FKBP-type peptidyl-prolyl cis-trans isomerase FklB [EC:5.2.1.8] E CH54_1830 FKBP-type peptidyl-prolyl cis-trans isomerase family protein K03774 slpA; FKBP-type peptidyl-prolyl cis-trans isomerase SlpA [EC:5.2.1.8] E CH54_2267 FKBP-type peptidyl-prolyl cis-trans isomerase family protein K03775 slyD; FKBP-type peptidyl-prolyl cis-trans isomerase SlyD [EC:5.2.1.8] D 5.2.1.9 farnesol 2-isomerase D 5.2.1.10 2-chloro-4-carboxymethylenebut-2-en-1,4-olide isomerase D 5.2.1.12 zeta-carotene isomerase D 5.2.1.13 prolycopene isomerase D 5.2.1.14 beta-carotene isomerase B 5.3 Intramolecular oxidoreductases C 5.3.1 Interconverting aldoses and ketoses, and related compounds D 5.3.1.1 triose-phosphate isomerase E CH54_2674 tpiA; triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1] D 5.3.1.3 D-arabinose isomerase D 5.3.1.4 L-arabinose isomerase E CH54_457 L-arabinose isomerase family protein K01804 araA; L-arabinose isomerase [EC:5.3.1.4] D 5.3.1.5 xylose isomerase E CH54_2444 xylA; xylose isomerase K01805 xylA; xylose isomerase [EC:5.3.1.5] D 5.3.1.6 ribose-5-phosphate isomerase E CH54_3398 rpiA; ribose 5-phosphate isomerase A K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6] D 5.3.1.7 mannose isomerase D 5.3.1.8 mannose-6-phosphate isomerase E CH54_441 manA; mannose-6-phosphate isomerase, class I K01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8] D 5.3.1.9 glucose-6-phosphate isomerase E CH54_2915 phosphoglucose isomerase family protein K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9] D 5.3.1.12 glucuronate isomerase E CH54_3078 glucuronate isomerase family protein K01812 uxaC; glucuronate isomerase [EC:5.3.1.12] D 5.3.1.13 arabinose-5-phosphate isomerase E CH54_1382 sugar isomerase, KpsF/GutQ family protein K02467 gutQ; arabinose 5-phosphate isomerase [EC:5.3.1.13] E CH54_3016 sugar isomerase, KpsF/GutQ family protein K06041 kdsD; arabinose-5-phosphate isomerase [EC:5.3.1.13] D 5.3.1.14 L-rhamnose isomerase D 5.3.1.15 D-lyxose ketol-isomerase D 5.3.1.16 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase E CH54_983 hisA; 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase K01814 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16] D 5.3.1.17 5-dehydro-4-deoxy-D-glucuronate isomerase E CH54_233 kduI/IolB family protein K01815 kduI; 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase [EC:5.3.1.17] D 5.3.1.20 ribose isomerase D 5.3.1.21 corticosteroid side-chain-isomerase D 5.3.1.22 hydroxypyruvate isomerase D 5.3.1.23 S-methyl-5-thioribose-1-phosphate isomerase E CH54_3577 mtnA; S-methyl-5-thioribose-1-phosphate isomerase K08963 mtnA; methylthioribose-1-phosphate isomerase [EC:5.3.1.23] D 5.3.1.24 phosphoribosylanthranilate isomerase E CH54_528 indole-3-glycerol phosphate synthase family protein K13498 trpCF; indole-3-glycerol phosphate synthase / phosphoribosylanthranilate isomerase [EC:4.1.1.48 5.3.1.24] D 5.3.1.25 L-fucose isomerase D 5.3.1.26 galactose-6-phosphate isomerase D 5.3.1.27 6-phospho-3-hexuloisomerase D 5.3.1.28 D-sedoheptulose-7-phosphate isomerase E CH54_3580 gmhA; phosphoheptose isomerase K03271 gmhA; D-sedoheptulose 7-phosphate isomerase [EC:5.3.1.28] D 5.3.1.29 ribose-1,5-bisphosphate isomerase D 5.3.1.30 5-deoxy-glucuronate isomerase E CH54_2369 iolB; 5-deoxy-glucuronate isomerase K03337 iolB; 5-deoxy-glucuronate isomerase [EC:5.3.1.30] D 5.3.1.31 sulfoquinovose isomerase D 5.3.1.32 (4S)-4-hydroxy-5-phosphooxypentane-2,3-dione isomerase E CH54_1908 antibiotic biosynthesis monooxygenase family protein K11530 lsrG; (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase [EC:5.3.1.32] D 5.3.1.33 L-erythrulose-1-phosphate isomerase D 5.3.1.34 D-erythrulose 4-phosphate isomerase D 5.3.1.35 2-dehydrotetronate isomerase E CH54_714 xylose isomerase-like TIM barrel family protein K22131 otnI; 2-dehydrotetronate isomerase [EC:5.3.1.35] D 5.3.1.36 D-apiose isomerase D 5.3.1.37 4-deoxy-4-sulfo-D-erythrose isomerase C 5.3.2 Interconverting keto- and enol-groups D 5.3.2.1 phenylpyruvate tautomerase D 5.3.2.2 oxaloacetate tautomerase D 5.3.2.3 TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase (dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose-forming) D 5.3.2.4 TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase (dTDP-3-dehydro-6-deoxy-alpha-D-glucopyranose-forming) D 5.3.2.5 2,3-diketo-5-methylthiopentyl-1-phosphate enolase D 5.3.2.6 2-hydroxymuconate tautomerase E CH54_2398 dmpI; 4-oxalocrotonate tautomerase enzyme family protein K01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6] D 5.3.2.7 ascopyrone tautomerase D 5.3.2.8 4-oxalomesaconate tautomerase C 5.3.3 Transposing C=C bonds D 5.3.3.1 steroid Delta-isomerase D 5.3.3.2 isopentenyl-diphosphate Delta-isomerase D 5.3.3.3 vinylacetyl-CoA Delta-isomerase D 5.3.3.4 muconolactone Delta-isomerase D 5.3.3.5 cholestenol Delta-isomerase D 5.3.3.6 methylitaconate Delta-isomerase D 5.3.3.7 aconitate Delta-isomerase D 5.3.3.8 Delta3-Delta2-enoyl-CoA isomerase E CH54_2852 fadB; fatty oxidation complex, alpha subunit FadB K01825 fadB; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase [EC:1.1.1.35 4.2.1.17 5.1.2.3 5.3.3.8] D 5.3.3.9 prostaglandin-A1 Delta-isomerase D 5.3.3.10 5-carboxymethyl-2-hydroxymuconate Delta-isomerase D 5.3.3.11 isopiperitenone Delta-isomerase D 5.3.3.12 L-dopachrome isomerase D 5.3.3.13 polyenoic fatty acid isomerase D 5.3.3.14 trans-2-decenoyl-[acyl-carrier protein] isomerase E CH54_9 fabA; beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA K01716 fabA; 3-hydroxyacyl-[acyl-carrier protein] dehydratase / trans-2-decenoyl-[acyl-carrier protein] isomerase [EC:4.2.1.59 5.3.3.14] D 5.3.3.17 trans-2,3-dihydro-3-hydroxyanthranilate isomerase D 5.3.3.18 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase D 5.3.3.19 3-[(4R)-4-hydroxycyclohexa-1,5-dien-1-yl]-2-oxopropanoate isomerase D 5.3.3.21 Delta3,5-Delta2,4-dienoyl-CoA isomerase D 5.3.3.22 lutein isomerase D 5.3.3.23 S-methyl-5-thioribulose 1-phosphate isomerase D 5.3.3.24 neopinone isomerase C 5.3.4 Transposing S-S bonds D 5.3.4.1 protein disulfide-isomerase E CH54_3420 DSBA-like thioredoxin domain protein K03981 dsbC; thiol:disulfide interchange protein DsbC [EC:5.3.4.1] C 5.3.99 Other intramolecular oxidoreductases D 5.3.99.2 prostaglandin-D synthase D 5.3.99.3 prostaglandin-E synthase D 5.3.99.4 prostaglandin-I synthase D 5.3.99.5 thromboxane-A synthase D 5.3.99.6 allene-oxide cyclase D 5.3.99.7 styrene-oxide isomerase D 5.3.99.8 capsanthin/capsorubin synthase D 5.3.99.9 neoxanthin synthase D 5.3.99.10 thiazole tautomerase D 5.3.99.11 2-keto-myo-inositol isomerase E CH54_2371 xylose isomerase-like TIM barrel family protein K06606 iolI; 2-keto-myo-inositol isomerase [EC:5.3.99.11] D 5.3.99.12 lachrymatory-factor synthase B 5.4 Intramolecular transferases C 5.4.1 Transferring acyl groups D 5.4.1.1 lysolecithin acylmutase D 5.4.1.3 2-methylfumaryl-CoA isomerase D 5.4.1.4 D-galactarolactone isomerase C 5.4.2 Phosphotransferases (phosphomutases) D 5.4.2.2 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) E CH54_1171 pgm; phosphoglucomutase, alpha-D-glucose phosphate-specific K01835 pgm; phosphoglucomutase [EC:5.4.2.2] D 5.4.2.3 phosphoacetylglucosamine mutase D 5.4.2.4 bisphosphoglycerate mutase D 5.4.2.5 phosphoglucomutase (glucose-cofactor) D 5.4.2.6 beta-phosphoglucomutase D 5.4.2.7 phosphopentomutase E CH54_3716 metalloenzyme superfamily protein K01839 deoB; phosphopentomutase [EC:5.4.2.7] E CH54_1866 deoB; phosphopentomutase K01839 deoB; phosphopentomutase [EC:5.4.2.7] D 5.4.2.8 phosphomannomutase D 5.4.2.9 phosphoenolpyruvate mutase D 5.4.2.10 phosphoglucosamine mutase E CH54_1984 glmM; phosphoglucosamine mutase K03431 glmM; phosphoglucosamine mutase [EC:5.4.2.10] D 5.4.2.11 phosphoglycerate mutase (2,3-diphosphoglycerate-dependent) E CH54_1123 phosphoglycerate mutase 1 family protein K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] E CH54_1851 histidine phosphatase super family protein K15634 gpmB; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] D 5.4.2.12 phosphoglycerate mutase (2,3-diphosphoglycerate-independent) E CH54_2659 gpmI; phosphoglycerate mutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] D 5.4.2.13 phosphogalactosamine mutase C 5.4.3 Transferring amino groups D 5.4.3.2 lysine 2,3-aminomutase D 5.4.3.3 lysine 5,6-aminomutase D 5.4.3.5 D-ornithine 4,5-aminomutase D 5.4.3.6 tyrosine 2,3-aminomutase D 5.4.3.7 leucine 2,3-aminomutase D 5.4.3.8 glutamate-1-semialdehyde 2,1-aminomutase E CH54_1720 hemL; glutamate-1-semialdehyde-2,1-aminomutase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8] D 5.4.3.9 glutamate 2,3-aminomutase D 5.4.3.10 phenylalanine aminomutase (L-beta-phenylalanine forming) D 5.4.3.11 phenylalanine aminomutase (D-beta-phenylalanine forming) C 5.4.4 Transferring hydroxy groups D 5.4.4.1 (hydroxyamino)benzene mutase D 5.4.4.2 isochorismate synthase E CH54_3171 isochorismate synthase family protein K02361 entC; isochorismate synthase [EC:5.4.4.2] E CH54_3950 isochorismate synthase family protein K02552 menF; menaquinone-specific isochorismate synthase [EC:5.4.4.2] E CH54_882 salicylate synthase K04781 mbtI; salicylate synthetase [EC:5.4.4.2 4.2.99.21] D 5.4.4.3 3-(hydroxyamino)phenol mutase D 5.4.4.4 geraniol isomerase D 5.4.4.5 9,12-octadecadienoate 8-hydroperoxide 8R-isomerase D 5.4.4.6 9,12-octadecadienoate 8-hydroperoxide 8S-isomerase D 5.4.4.7 hydroperoxy icosatetraenoate isomerase D 5.4.4.8 linalool isomerase C 5.4.99 Transferring other groups D 5.4.99.1 methylaspartate mutase D 5.4.99.2 methylmalonyl-CoA mutase D 5.4.99.3 2-acetolactate mutase D 5.4.99.4 2-methyleneglutarate mutase D 5.4.99.5 chorismate mutase E CH54_1605 chorismate mutase K14170 pheA; chorismate mutase / prephenate dehydratase [EC:5.4.99.5 4.2.1.51] E CH54_1606 tyrA; chorismate mutase K14187 tyrA; chorismate mutase / prephenate dehydrogenase [EC:5.4.99.5 1.3.1.12] D 5.4.99.7 lanosterol synthase D 5.4.99.8 cycloartenol synthase D 5.4.99.9 UDP-galactopyranose mutase D 5.4.99.11 isomaltulose synthase D 5.4.99.12 tRNA pseudouridine38-40 synthase E CH54_3890 truA; tRNA pseudouridine(38-40) synthase K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12] D 5.4.99.13 isobutyryl-CoA mutase D 5.4.99.14 4-carboxymethyl-4-methylbutenolide mutase D 5.4.99.15 (1->4)-alpha-D-glucan 1-alpha-D-glucosylmutase D 5.4.99.16 maltose alpha-D-glucosyltransferase D 5.4.99.17 squalene---hopene cyclase D 5.4.99.18 5-(carboxyamino)imidazole ribonucleotide mutase E CH54_3758 purE; phosphoribosylaminoimidazole carboxylase, catalytic subunit K01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18] D 5.4.99.19 16S rRNA pseudouridine516 synthase E CH54_3993 pseudouridine synthase family protein K06183 rsuA; 16S rRNA pseudouridine516 synthase [EC:5.4.99.19] D 5.4.99.20 23S rRNA pseudouridine2457 synthase E CH54_118 pseudouridine synthase family protein K06181 rluE; 23S rRNA pseudouridine2457 synthase [EC:5.4.99.20] D 5.4.99.21 23S rRNA pseudouridine2604 synthase E CH54_189 pseudouridine synthase family protein K06182 rluF; 23S rRNA pseudouridine2604 synthase [EC:5.4.99.21] D 5.4.99.22 23S rRNA pseudouridine2605 synthase E CH54_503 pseudouridine synthase family protein K06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22] D 5.4.99.23 23S rRNA pseudouridine1911/1915/1917 synthase E CH54_1602 pseudouridine synthase, RluA family protein K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23] D 5.4.99.24 23S rRNA pseudouridine955/2504/2580 synthase E CH54_71 pseudouridine synthase, RluA family protein K06179 rluC; 23S rRNA pseudouridine955/2504/2580 synthase [EC:5.4.99.24] D 5.4.99.25 tRNA pseudouridine55 synthase E CH54_1976 truB; tRNA pseudouridine(55) synthase K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25] D 5.4.99.26 tRNA pseudouridine65 synthase E CH54_3514 RNA pseudouridylate synthase family protein K06175 truC; tRNA pseudouridine65 synthase [EC:5.4.99.26] D 5.4.99.27 tRNA pseudouridine13 synthase E CH54_1684 tRNA pseudouridine synthase, TruD family protein K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27] D 5.4.99.28 tRNA pseudouridine32 synthase E CH54_1812 RNA pseudouridylate synthase family protein K06177 rluA; tRNA pseudouridine32 synthase / 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29] E CH54_850 RNA pseudouridylate synthase family protein K06177 rluA; tRNA pseudouridine32 synthase / 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29] D 5.4.99.29 23S rRNA pseudouridine746 synthase E CH54_1812 RNA pseudouridylate synthase family protein K06177 rluA; tRNA pseudouridine32 synthase / 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29] E CH54_850 RNA pseudouridylate synthase family protein K06177 rluA; tRNA pseudouridine32 synthase / 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29] D 5.4.99.30 UDP-arabinopyranose mutase D 5.4.99.31 thalianol synthase D 5.4.99.32 protostadienol synthase D 5.4.99.33 cucurbitadienol synthase D 5.4.99.34 germanicol synthase D 5.4.99.35 taraxerol synthase D 5.4.99.36 isomultiflorenol synthase D 5.4.99.37 dammaradiene synthase D 5.4.99.38 camelliol C synthase D 5.4.99.39 beta-amyrin synthase D 5.4.99.40 alpha-amyrin synthase D 5.4.99.41 lupeol synthase D 5.4.99.42 tRNA pseudouridine31 synthase D 5.4.99.43 21S rRNA pseudouridine2819 synthase D 5.4.99.44 mitochondrial tRNA pseudouridine27/28 synthase D 5.4.99.45 tRNA pseudouridine38/39 synthase D 5.4.99.46 shionone synthase D 5.4.99.47 parkeol synthase D 5.4.99.48 achilleol B synthase D 5.4.99.49 glutinol synthase D 5.4.99.50 friedelin synthase D 5.4.99.51 baccharis oxide synthase D 5.4.99.52 alpha-seco-amyrin synthase D 5.4.99.53 marneral synthase D 5.4.99.54 beta-seco-amyrin synthase D 5.4.99.55 delta-amyrin synthase D 5.4.99.56 tirucalladienol synthase D 5.4.99.57 baruol synthase D 5.4.99.58 methylornithine synthase D 5.4.99.59 dTDP-fucopyranose mutase D 5.4.99.60 cobalt-precorrin-8 methylmutase E CH54_935 precorrin-8X methylmutase family protein K06042 cobH-cbiC; precorrin-8X/cobalt-precorrin-8 methylmutase [EC:5.4.99.61 5.4.99.60] D 5.4.99.61 precorrin-8X methylmutase E CH54_935 precorrin-8X methylmutase family protein K06042 cobH-cbiC; precorrin-8X/cobalt-precorrin-8 methylmutase [EC:5.4.99.61 5.4.99.60] D 5.4.99.62 D-ribose pyranase E CH54_2543 rbsD / FucU transport family protein K06726 rbsD; D-ribose pyranase [EC:5.4.99.62] D 5.4.99.63 ethylmalonyl-CoA mutase D 5.4.99.64 2-hydroxyisobutanoyl-CoA mutase D 5.4.99.65 pre-alpha-onocerin synthase D 5.4.99.66 alpha-onocerin synthase D 5.4.99.67 4-amino-4-deoxychorismate mutase B 5.5 Intramolecular lyases C 5.5.1 Intramolecular lyases (only sub-subclass identified to date) D 5.5.1.1 muconate cycloisomerase D 5.5.1.2 3-carboxy-cis,cis-muconate cycloisomerase D 5.5.1.3 tetrahydroxypteridine cycloisomerase D 5.5.1.4 inositol-3-phosphate synthase D 5.5.1.5 carboxy-cis,cis-muconate cyclase D 5.5.1.6 chalcone isomerase D 5.5.1.7 chloromuconate cycloisomerase D 5.5.1.8 (+)-bornyl diphosphate synthase D 5.5.1.9 cycloeucalenol cycloisomerase D 5.5.1.10 alpha-pinene-oxide decyclase D 5.5.1.11 dichloromuconate cycloisomerase D 5.5.1.12 copalyl diphosphate synthase D 5.5.1.13 ent-copalyl diphosphate synthase D 5.5.1.14 syn-copalyl-diphosphate synthase D 5.5.1.15 terpentedienyl-diphosphate synthase D 5.5.1.16 halimadienyl-diphosphate synthase D 5.5.1.17 (S)-beta-macrocarpene synthase D 5.5.1.18 lycopene epsilon-cyclase D 5.5.1.19 lycopene beta-cyclase D 5.5.1.20 prosolanapyrone-III cycloisomerase D 5.5.1.22 (-)-bornyl diphosphate synthase D 5.5.1.23 aklanonic acid methyl ester cyclase D 5.5.1.24 tocopherol cyclase D 5.5.1.25 3,6-anhydro-L-galactonate cycloisomerase D 5.5.1.26 nogalonic acid methyl ester cyclase D 5.5.1.27 D-galactarolactone cycloisomerase D 5.5.1.28 (-)-kolavenyl diphosphate synthase D 5.5.1.29 (+)-kolavenyl diphosphate synthase D 5.5.1.30 labda-7,13-dienyl diphosphate synthase D 5.5.1.31 hapalindole H synthase D 5.5.1.32 12-epi-hapalindole U synthase D 5.5.1.33 12-epi-fischerindole U synthase D 5.5.1.34 (+)-cis,trans-nepetalactol synthase D 5.5.1.35 (+)-cis,cis-nepetalactol synthase B 5.6 Isomerases altering macromolecular conformation C 5.6.1 Enzymes altering polypeptide conformation or assembly D 5.6.1.1 microtubule-severing ATPase D 5.6.1.2 dynein ATPase D 5.6.1.3 plus-end-directed kinesin ATPase D 5.6.1.4 minus-end-directed kinesin ATPase D 5.6.1.5 proteasome ATPase D 5.6.1.6 channel-conductance-controlling ATPase D 5.6.1.7 chaperonin ATPase E CH54_2063 groL; chaperonin GroL K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D 5.6.1.8 myosin ATPase D 5.6.1.9 (R)-2-hydroxyacyl-CoA dehydratase activating ATPase C 5.6.2 Enzymes altering nucleic acid conformation D 5.6.2.1 DNA topoisomerase E CH54_497 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1] E CH54_569 topB; DNA topoisomerase III family protein K03169 topB; DNA topoisomerase III [EC:5.6.2.1] D 5.6.2.2 DNA topoisomerase (ATP-hydrolysing) E CH54_3965 gyrA; DNA gyrase, A subunit K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] E CH54_2493 gyrB; DNA gyrase, B subunit K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] E CH54_3130 parC; DNA topoisomerase IV, A subunit K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] E CH54_3126 parE; DNA topoisomerase IV, B subunit K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] D 5.6.2.3 DNA 5'-3' helicase E CH54_3351 dnaB; replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3] E CH54_3793 hypothetical protein K02314 dnaB; replicative DNA helicase [EC:5.6.2.3] E CH54_2935 dnaB; replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3] E CH54_2156 dnaB; replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3] E CH54_1061 DEAD_2 family protein K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3] E CH54_607 DEAD_2 family protein K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3] D 5.6.2.4 DNA 3'-5' helicase E CH54_621 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] E CH54_2789 recQ; ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4] E CH54_2578 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4] E CH54_2745 rep; ATP-dependent DNA helicase Rep K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4] E CH54_1524 hypothetical protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E CH54_2780 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E CH54_17 hypothetical protein K03658 helD; DNA helicase IV [EC:5.6.2.4] E CH54_103 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4] E CH54_2689 priA; primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4] E CH54_29 cas3f; CRISPR-associated helicase Cas3, subtype I-F/YPEST K07012 cas3; CRISPR-associated endonuclease/helicase Cas3 [EC:3.1.-.- 5.6.2.4] B 5.99 Other isomerases C 5.99.1 Sole sub-subclass for isomerases that do not belong in the other subclasses D 5.99.1.1 thiocyanate isomerase D 5.99.1.4 2-hydroxychromene-2-carboxylate isomerase # A6. Ligases B 6.1 Forming carbon-oxygen bonds C 6.1.1 Ligases forming aminoacyl-tRNA and related compounds D 6.1.1.1 tyrosine---tRNA ligase E CH54_322 tyrS; tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1] D 6.1.1.2 tryptophan---tRNA ligase E CH54_2300 trpS; tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] D 6.1.1.3 threonine---tRNA ligase E CH54_252 thrS; threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3] D 6.1.1.4 leucine---tRNA ligase E CH54_1208 leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4] D 6.1.1.5 isoleucine---tRNA ligase E CH54_1832 ileS; isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5] D 6.1.1.6 lysine---tRNA ligase E CH54_3423 lysS; lysine--tRNA ligase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6] D 6.1.1.7 alanine---tRNA ligase E CH54_1627 alaS; alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7] D 6.1.1.9 valine---tRNA ligase E CH54_1933 valS; valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9] D 6.1.1.10 methionine---tRNA ligase E CH54_995 metG; methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10] D 6.1.1.11 serine---tRNA ligase E CH54_4084 serS; serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11] D 6.1.1.12 aspartate---tRNA ligase E CH54_627 aspS; aspartate--tRNA ligase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12] D 6.1.1.13 D-alanine---poly(phosphoribitol) ligase D 6.1.1.14 glycine---tRNA ligase E CH54_2472 glyQ; glycine--tRNA ligase, alpha subunit K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14] E CH54_2471 glyS; glycine--tRNA ligase, beta subunit K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14] D 6.1.1.15 proline---tRNA ligase E CH54_3548 proS; proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15] D 6.1.1.16 cysteine---tRNA ligase E CH54_3761 cysS; cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16] D 6.1.1.17 glutamate---tRNA ligase E CH54_1284 gltX; glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] D 6.1.1.18 glutamine---tRNA ligase E CH54_1182 glnS; glutamine--tRNA ligase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18] D 6.1.1.19 arginine---tRNA ligase E CH54_635 argS; arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19] D 6.1.1.20 phenylalanine---tRNA ligase E CH54_256 pheS; phenylalanine--tRNA ligase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] E CH54_257 pheT; phenylalanine--tRNA ligase, beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] D 6.1.1.21 histidine---tRNA ligase E CH54_1448 hisS; histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21] D 6.1.1.22 asparagine---tRNA ligase E CH54_4117 asnS; asparagine--tRNA ligase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22] D 6.1.1.23 aspartate---tRNAAsn ligase D 6.1.1.24 glutamate---tRNAGln ligase D 6.1.1.26 pyrrolysine---tRNAPyl ligase D 6.1.1.27 O-phospho-L-serine---tRNA ligase C 6.1.2 acid-alcohol ligases (ester synthases) D 6.1.2.1 D-alanine---(R)-lactate ligase D 6.1.2.2 nebramycin 5' synthase C 6.1.3 Cyclo-ligases D 6.1.3.1 olefin beta-lactone synthetase B 6.2 Forming carbon-sulfur bonds C 6.2.1 Acid-thiol ligases D 6.2.1.1 acetate---CoA ligase E CH54_2204 acs; acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] D 6.2.1.2 medium-chain acyl-CoA ligase D 6.2.1.3 long-chain-fatty-acid---CoA ligase E CH54_604 AMP-binding enzyme family protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] E CH54_1793 AMP-binding enzyme family protein K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3] D 6.2.1.4 succinate---CoA ligase (GDP-forming) D 6.2.1.5 succinate---CoA ligase (ADP-forming) E CH54_1144 sucD; succinate-CoA ligase, alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5] E CH54_1145 sucC; succinate-CoA ligase, beta subunit K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5] D 6.2.1.6 glutarate---CoA ligase D 6.2.1.7 cholate---CoA ligase D 6.2.1.8 oxalate---CoA ligase D 6.2.1.9 malate---CoA ligase D 6.2.1.10 carboxylic acid---CoA ligase (GDP-forming) D 6.2.1.11 biotin---CoA ligase D 6.2.1.12 4-coumarate---CoA ligase D 6.2.1.13 acetate---CoA ligase (ADP-forming) D 6.2.1.14 6-carboxyhexanoate---CoA ligase D 6.2.1.15 arachidonate---CoA ligase D 6.2.1.16 acetoacetate---CoA ligase D 6.2.1.17 propionate---CoA ligase D 6.2.1.18 citrate---CoA ligase D 6.2.1.19 long-chain-fatty-acid---protein ligase D 6.2.1.20 long-chain-fatty-acid---[acyl-carrier-protein] ligase E CH54_3479 acyltransferase family protein K05939 aas; acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase / long-chain-fatty-acid--[acyl-carrier-protein] ligase [EC:2.3.1.40 6.2.1.20] D 6.2.1.22 [citrate (pro-3S)-lyase] ligase E CH54_863 citC; [citrate (pro-3S)-lyase] ligase K01910 citC; [citrate (pro-3S)-lyase] ligase [EC:6.2.1.22] D 6.2.1.23 dicarboxylate---CoA ligase D 6.2.1.24 phytanate---CoA ligase D 6.2.1.25 benzoate---CoA ligase D 6.2.1.26 o-succinylbenzoate---CoA ligase E CH54_3955 menE; O-succinylbenzoate-CoA ligase K01911 menE; o-succinylbenzoate---CoA ligase [EC:6.2.1.26] D 6.2.1.27 4-hydroxybenzoate---CoA ligase D 6.2.1.28 3alpha,7alpha-dihydroxy-5beta-cholestanate---CoA ligase D 6.2.1.30 phenylacetate---CoA ligase D 6.2.1.31 2-furoate---CoA ligase D 6.2.1.32 anthranilate---CoA ligase D 6.2.1.33 4-chlorobenzoate---CoA ligase D 6.2.1.34 trans-feruloyl-CoA synthase D 6.2.1.35 acetate---[acyl-carrier protein] ligase D 6.2.1.36 3-hydroxypropionyl-CoA synthase D 6.2.1.37 3-hydroxybenzoate---CoA ligase D 6.2.1.38 (2,2,3-trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA synthase D 6.2.1.39 [butirosin acyl-carrier protein]---L-glutamate ligase D 6.2.1.40 4-hydroxybutyrate---CoA ligase (AMP-forming) D 6.2.1.41 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate---CoA ligase D 6.2.1.42 3-oxocholest-4-en-26-oate---CoA ligase D 6.2.1.43 2-hydroxy-7-methoxy-5-methyl-1-naphthoate---CoA ligase D 6.2.1.44 3-(methylthio)propionyl---CoA ligase D 6.2.1.45 E1 ubiquitin-activating enzyme D 6.2.1.46 L-allo-isoleucine---holo-[CmaA peptidyl-carrier protein] ligase D 6.2.1.47 medium-chain-fatty-acid---[acyl-carrier-protein] ligase D 6.2.1.48 carnitine---CoA ligase D 6.2.1.49 long-chain fatty acid adenylyltransferase FadD28 D 6.2.1.50 4-hydroxybenzoate adenylyltransferase FadD22 D 6.2.1.51 4-hydroxyphenylalkanoate adenylyltransferase FadD29 D 6.2.1.52 L-firefly luciferin---CoA ligase D 6.2.1.53 L-proline---[L-prolyl-carrier protein] ligase D 6.2.1.54 D-alanine---[D-alanyl-carrier protein] ligase D 6.2.1.55 E1 SAMP-activating enzyme D 6.2.1.56 4-hydroxybutyrate---CoA ligase (ADP-forming) D 6.2.1.57 long-chain fatty acid adenylase/transferase FadD23 D 6.2.1.58 isophthalate---CoA ligase D 6.2.1.59 long-chain fatty acid adenylase/transferase FadD26 D 6.2.1.60 marinolic acid---CoA ligase D 6.2.1.61 salicylate---[aryl-carrier protein] ligase D 6.2.1.62 3,4-dihydroxybenzoate---[aryl-carrier protein] ligase D 6.2.1.63 L-arginine---[L-arginyl-carrier protein] ligase E CH54_3164 amino acid adenylation domain protein K24101 vabF; L-arginine---[L-arginyl-carrier protein] ligase [EC:6.2.1.63] D 6.2.1.64 E1 NEDD8-activating enzyme D 6.2.1.65 salicylate---CoA ligase D 6.2.1.66 glyine---[glycyl-carrier protein] ligase D 6.2.1.67 L-alanine---[L-alanyl-carrier protein] ligase D 6.2.1.68 L-glutamate---[L-glutamyl-carrier protein] ligase D 6.2.1.69 L-cysteine---[L-cysteinyl-carrier protein] ligase E CH54_888 amino acid adenylation domain protein K12240 pchF; L-cysteine---[L-cysteinyl-carrier protein] ligase PchF [EC:6.2.1.69] D 6.2.1.70 L-threonine---[L-threonyl-carrier protein] ligase D 6.2.1.71 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase E CH54_3172 (2,3-dihydroxybenzoyl)adenylate synthase K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] D 6.2.1.72 L-serine---[L-seryl-carrier protein] ligase D 6.2.1.73 L-tryptophan---[L-tryptophyl-carrier protein] ligase D 6.2.1.74 3-amino-5-hydroxybenzoate---[acyl-carrier protein] ligase D 6.2.1.75 indoleacetate---CoA ligase D 6.2.1.76 malonate---CoA ligase C 6.2.2 Amide---thiol ligases D 6.2.2.1 thioglycine synthase D 6.2.2.2 oxazoline synthase D 6.2.2.3 thiazoline synthase B 6.3 Forming carbon-nitrogen bonds C 6.3.1 Acid-D-ammonia (or amine) ligases (amide synthases) D 6.3.1.1 aspartate---ammonia ligase E CH54_2538 asnA; aspartate--ammonia ligase K01914 asnA; aspartate--ammonia ligase [EC:6.3.1.1] D 6.3.1.2 glutamine synthetase E CH54_2566 glnA; glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2] D 6.3.1.4 aspartate---ammonia ligase (ADP-forming) D 6.3.1.5 NAD+ synthase D 6.3.1.6 glutamate---ethylamine ligase D 6.3.1.7 4-methyleneglutamate---ammonia ligase D 6.3.1.8 glutathionylspermidine synthase D 6.3.1.9 trypanothione synthase D 6.3.1.10 adenosylcobinamide-phosphate synthase E CH54_936 cobD; cobalamin biosynthesis protein CobD K02227 cbiB; adenosylcobinamide-phosphate synthase [EC:6.3.1.10] D 6.3.1.11 glutamate---putrescine ligase D 6.3.1.12 D-aspartate ligase D 6.3.1.13 L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase D 6.3.1.14 diphthine---ammonia ligase D 6.3.1.15 8-demethylnovobiocic acid synthase D 6.3.1.17 beta-citrylglutamate synthase D 6.3.1.18 gamma-glutamylanilide synthase D 6.3.1.19 prokaryotic ubiquitin-like protein ligase D 6.3.1.20 lipoate---protein ligase E CH54_272 lipoyltransferase and lipoate-ligase family protein K03800 lplA; lipoate---protein ligase [EC:6.3.1.20] D 6.3.1.21 phosphoribosylglycinamide formyltransferase 2 E CH54_170 purT; phosphoribosylglycinamide formyltransferase 2 K08289 purT; phosphoribosylglycinamide formyltransferase 2 [EC:6.3.1.21] C 6.3.2 Acid-D-amino-acid ligases (peptide synthases) D 6.3.2.1 pantoate---beta-alanine ligase (AMP-forming) E CH54_1733 panC; pantoate--beta-alanine ligase K01918 panC; pantoate--beta-alanine ligase [EC:6.3.2.1] D 6.3.2.2 glutamate---cysteine ligase E CH54_1619 gshA; glutamate--cysteine ligase K01919 gshA; glutamate--cysteine ligase [EC:6.3.2.2] D 6.3.2.3 glutathione synthase E CH54_3377 gshB; glutathione synthase K01920 gshB; glutathione synthase [EC:6.3.2.3] D 6.3.2.4 D-alanine---D-alanine ligase E CH54_1777 D-alanine--D-alanine ligase family protein K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] E CH54_3593 D-alanine--D-alanine ligase family protein K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] D 6.3.2.5 phosphopantothenate---cysteine ligase (CTP) E CH54_2644 coaBC; phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase K13038 coaBC; phosphopantothenoylcysteine decarboxylase / phosphopantothenate---cysteine ligase [EC:4.1.1.36 6.3.2.5] D 6.3.2.6 phosphoribosylaminoimidazolesuccinocarboxamide synthase E CH54_1343 purC; phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6] D 6.3.2.7 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate---L-lysine ligase D 6.3.2.8 UDP-N-acetylmuramate---L-alanine ligase E CH54_1778 murC; UDP-N-acetylmuramate--L-alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8] D 6.3.2.9 UDP-N-acetylmuramoyl-L-alanine---D-glutamate ligase E CH54_1781 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] D 6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase E CH54_1783 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase family protein K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10] D 6.3.2.11 carnosine synthase D 6.3.2.12 dihydrofolate synthase E CH54_3895 folC; bifunctional FolC family protein K11754 folC; dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17] D 6.3.2.13 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate---2,6-diaminopimelate ligase E CH54_1784 murE; UDP-N-acetylmuramyl-tripeptide synthetase family protein K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13] D 6.3.2.14 enterobactin synthase E CH54_3173 isochorismatase family protein K01252 entB; bifunctional isochorismate lyase / aryl carrier protein [EC:3.3.2.1 6.3.2.14] E CH54_853 4'-phosphopantetheinyl transferase superfamily protein K02362 entD; enterobactin synthetase component D [EC:6.3.2.14 2.7.8.-] E CH54_891 4'-phosphopantetheinyl transferase superfamily protein K02362 entD; enterobactin synthetase component D [EC:6.3.2.14 2.7.8.-] E CH54_3172 (2,3-dihydroxybenzoyl)adenylate synthase K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] D 6.3.2.16 D-alanine---alanyl-poly(glycerolphosphate) ligase D 6.3.2.17 tetrahydrofolate synthase E CH54_3895 folC; bifunctional FolC family protein K11754 folC; dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17] D 6.3.2.18 gamma-glutamylhistamine synthase D 6.3.2.20 indoleacetate---lysine synthetase D 6.3.2.23 homoglutathione synthase D 6.3.2.24 tyrosine---arginine ligase D 6.3.2.25 tubulin---tyrosine ligase D 6.3.2.26 N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase D 6.3.2.29 cyanophycin synthase (L-aspartate-adding) D 6.3.2.30 cyanophycin synthase (L-arginine-adding) D 6.3.2.31 coenzyme F420-0:L-glutamate ligase D 6.3.2.32 coenzyme gamma-F420-2:alpha-L-glutamate ligase D 6.3.2.33 tetrahydrosarcinapterin synthase D 6.3.2.34 coenzyme F420-1:gamma-L-glutamate ligase D 6.3.2.35 D-alanine---D-serine ligase D 6.3.2.36 4-phosphopantoate---beta-alanine ligase D 6.3.2.37 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate---D-lysine ligase D 6.3.2.38 N2-citryl-N6-acetyl-N6-hydroxylysine synthase D 6.3.2.39 aerobactin synthase D 6.3.2.40 cyclopeptine synthase D 6.3.2.41 N-acetylaspartylglutamate synthase D 6.3.2.42 N-acetylaspartylglutamylglutamate synthase D 6.3.2.43 [amino-group carrier protein]---L-2-aminoadipate ligase D 6.3.2.44 pantoate---beta-alanine ligase (ADP-forming) D 6.3.2.45 UDP-N-acetylmuramate---L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate ligase E CH54_2004 mpl; L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase K02558 mpl; UDP-N-acetylmuramate: L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase [EC:6.3.2.45] D 6.3.2.46 fumarate---(S)-2,3-diaminopropanoate ligase D 6.3.2.47 dapdiamide synthase D 6.3.2.48 L-arginine-specific L-amino acid ligase D 6.3.2.49 L-alanine---L-anticapsin ligase D 6.3.2.50 tenuazonic acid synthetase D 6.3.2.51 phosphopantothenate---cysteine ligase (ATP) D 6.3.2.52 jasmonoyl---L-amino acid ligase D 6.3.2.53 UDP-N-acetylmuramoyl-L-alanine---L-glutamate ligase D 6.3.2.54 L-2,3-diaminopropanoate---citrate ligase D 6.3.2.55 2-[(L-alanin-3-ylcarbamoyl)methyl]-3-(2-aminoethylcarbamoyl)-2-hydroxypropanoate synthase D 6.3.2.56 staphyloferrin B synthase D 6.3.2.57 staphyloferrin A synthase D 6.3.2.58 D-ornithine---citrate ligase D 6.3.2.59 3-methyl-D-ornithine---L-lysine ligase D 6.3.2.60 glutamate---[amino group carrier protein] ligase D 6.3.2.61 tubulin-glutamate ligase D 6.3.2.62 beta-tubulin-glutamate ligase C 6.3.3 Cyclo-ligases D 6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase E CH54_1354 purM; phosphoribosylformylglycinamidine cyclo-ligase K01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1] D 6.3.3.2 5-formyltetrahydrofolate cyclo-ligase E CH54_3400 5-formyltetrahydrofolate cyclo-ligase K01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2] D 6.3.3.3 dethiobiotin synthase E CH54_433 bioD; dethiobiotin synthase K01935 bioD; dethiobiotin synthetase [EC:6.3.3.3] E CH54_1104 bioD; dethiobiotin synthase K01935 bioD; dethiobiotin synthetase [EC:6.3.3.3] D 6.3.3.4 (carboxyethyl)arginine beta-lactam-synthase D 6.3.3.5 O-ureido-D-serine cyclo-ligase D 6.3.3.6 carbapenam-3-carboxylate synthase D 6.3.3.7 Ni-sirohydrochlorin a,c-diamide reductive cyclase C 6.3.4 Other carbon-nitrogen ligases D 6.3.4.2 CTP synthase (glutamine hydrolysing) E CH54_1708 pyrG; CTP synthase K01937 pyrG; CTP synthase [EC:6.3.4.2] D 6.3.4.3 formate---tetrahydrofolate ligase E CH54_462 formate--tetrahydrofolate ligase family protein K01938 fhs; formate--tetrahydrofolate ligase [EC:6.3.4.3] D 6.3.4.4 adenylosuccinate synthase E CH54_2033 purA; adenylosuccinate synthase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4] D 6.3.4.5 argininosuccinate synthase E CH54_912 argG; argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5] D 6.3.4.6 urea carboxylase D 6.3.4.7 ribose-5-phosphate---ammonia ligase D 6.3.4.8 imidazoleacetate---phosphoribosyldiphosphate ligase D 6.3.4.9 biotin---[methylmalonyl-CoA-carboxytransferase] ligase D 6.3.4.10 biotin---[propionyl-CoA-carboxylase (ATP-hydrolysing)] ligase D 6.3.4.11 biotin---[methylcrotonoyl-CoA-carboxylase] ligase D 6.3.4.12 glutamate---methylamine ligase D 6.3.4.13 phosphoribosylamine---glycine ligase E CH54_2895 purD; phosphoribosylamine--glycine ligase K01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13] D 6.3.4.14 biotin carboxylase E CH54_2963 accC; acetyl-CoA carboxylase, biotin carboxylase subunit K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] D 6.3.4.15 biotin---[biotin carboxyl-carrier protein] ligase E CH54_2863 biotin operon repressor K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15] D 6.3.4.16 carbamoyl-phosphate synthase (ammonia) D 6.3.4.17 formate---dihydrofolate ligase D 6.3.4.18 5-(carboxyamino)imidazole ribonucleotide synthase E CH54_3757 purK; phosphoribosylaminoimidazole carboxylase, ATPase subunit K01589 purK; 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18] D 6.3.4.19 tRNAIle-lysidine synthase E CH54_3541 tilS; tRNA(Ile)-lysidine synthetase K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19] D 6.3.4.20 7-cyano-7-deazaguanine synthase E CH54_3694 queC; queuosine biosynthesis protein QueC K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20] D 6.3.4.21 nicotinate phosphoribosyltransferase E CH54_4118 pncB; nicotinate phosphoribosyltransferase K00763 pncB; nicotinate phosphoribosyltransferase [EC:6.3.4.21] D 6.3.4.22 tRNAIle2-agmatinylcytidine synthase D 6.3.4.23 formate---phosphoribosylaminoimidazolecarboxamide ligase D 6.3.4.24 tyramine---L-glutamate ligase D 6.3.4.25 2-amino-2'-deoxyadenylo-succinate synthase C 6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor D 6.3.5.1 NAD+ synthase (glutamine-hydrolysing) E CH54_1480 nadE; NAD+ synthetase K01950 E6.3.5.1; NAD+ synthase (glutamine-hydrolysing) [EC:6.3.5.1] D 6.3.5.2 GMP synthase (glutamine-hydrolysing) E CH54_1440 guaA; GMP synthase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] D 6.3.5.3 phosphoribosylformylglycinamidine synthase E CH54_1484 purL; phosphoribosylformylglycinamidine synthase K01952 PFAS; phosphoribosylformylglycinamidine synthase [EC:6.3.5.3] D 6.3.5.4 asparagine synthase (glutamine-hydrolysing) E CH54_1188 asnB; asparagine synthase K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] D 6.3.5.5 carbamoyl-phosphate synthase (glutamine-hydrolysing) E CH54_1826 carB; carbamoyl-phosphate synthase, large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] E CH54_1827 carA; carbamoyl-phosphate synthase, small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] D 6.3.5.6 asparaginyl-tRNA synthase (glutamine-hydrolysing) D 6.3.5.7 glutaminyl-tRNA synthase (glutamine-hydrolysing) D 6.3.5.9 hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing) E CH54_937 cobB; cobyrinic acid a,c-diamide synthase K02224 cobB-cbiA; cobyrinic acid a,c-diamide synthase [EC:6.3.5.9 6.3.5.11] D 6.3.5.10 adenosylcobyric acid synthase (glutamine-hydrolysing) E CH54_921 cobQ; cobyric acid synthase CobQ K02232 cobQ; adenosylcobyric acid synthase [EC:6.3.5.10] D 6.3.5.11 cobyrinate a,c-diamide synthase E CH54_937 cobB; cobyrinic acid a,c-diamide synthase K02224 cobB-cbiA; cobyrinic acid a,c-diamide synthase [EC:6.3.5.9 6.3.5.11] D 6.3.5.12 Ni-sirohydrochlorin a,c-diamide synthase D 6.3.5.13 lipid II isoglutaminyl synthase (glutamine-hydrolysing) B 6.4 Forming carbon-carbon bonds C 6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date) D 6.4.1.1 pyruvate carboxylase D 6.4.1.2 acetyl-CoA carboxylase E CH54_2963 accC; acetyl-CoA carboxylase, biotin carboxylase subunit K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] E CH54_3536 accA; acetyl-CoA carboxylase, carboxyl transferase, alpha subunit K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15] E CH54_3893 accD; acetyl-CoA carboxylase, carboxyl transferase, beta subunit K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15] D 6.4.1.3 propionyl-CoA carboxylase D 6.4.1.4 methylcrotonoyl-CoA carboxylase D 6.4.1.5 geranoyl-CoA carboxylase D 6.4.1.6 acetone carboxylase D 6.4.1.7 2-oxoglutarate carboxylase D 6.4.1.8 acetophenone carboxylase D 6.4.1.9 coenzyme F430 synthetase B 6.5 Forming phosphoric-ester bonds C 6.5.1 Ligases that form phosphoric-ester bonds (only sub-subclass identified to date) D 6.5.1.1 DNA ligase (ATP) D 6.5.1.2 DNA ligase (NAD+) E CH54_1291 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] E CH54_2583 NAD-dependent DNA ligase adenylation domain protein K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D 6.5.1.3 RNA ligase (ATP) D 6.5.1.4 RNA 3'-terminal-phosphate cyclase (ATP) D 6.5.1.5 RNA 3'-terminal-phosphate cyclase (GTP) D 6.5.1.6 DNA ligase (ATP or NAD+) D 6.5.1.7 DNA ligase (ATP, ADP or GTP) D 6.5.1.8 3'-phosphate/5'-hydroxy nucleic acid ligase D 6.5.1.9 cyclic 2,3-diphosphoglycerate synthase B 6.6 Forming nitrogen-metal bonds C 6.6.1 Forming coordination complexes D 6.6.1.1 magnesium chelatase D 6.6.1.2 cobaltochelatase B 6.7 Forming nitrogen-nitrogen bonds C 6.7.1 Forming diazo bonds D 6.7.1.1 3-amino-2-hydroxy-4-methoxybenzoate diazotase D 6.7.1.2 3-aminoavenalumate diazotase # A7. Translocases B 7.1 Catalysing the translocation of protons C 7.1.1 Linked to oxidoreductase reactions D 7.1.1.1 proton-translocating NAD(P)+ transhydrogenase E CH54_377 pntA; NAD(P)(+) transhydrogenase (AB-specific), alpha subunit K00324 pntA; proton-translocating NAD(P)+ transhydrogenase subunit alpha [EC:7.1.1.1] E CH54_378 NAD(P) transhydrogenase beta subunit K00325 pntB; proton-translocating NAD(P)+ transhydrogenase subunit beta [EC:7.1.1.1] D 7.1.1.2 NADH:ubiquinone reductase (H+-translocating) E CH54_3925 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 family protein K00330 nuoA; NADH-quinone oxidoreductase subunit A [EC:7.1.1.2] E CH54_3926 NADH-quinone oxidoreductase, B subunit K00331 nuoB; NADH-quinone oxidoreductase subunit B [EC:7.1.1.2] E CH54_3928 nuoE; NADH-quinone oxidoreductase, E subunit K00334 nuoE; NADH-quinone oxidoreductase subunit E [EC:7.1.1.2] E CH54_3929 nuoF; NADH oxidoreductase (quinone), F subunit K00335 nuoF; NADH-quinone oxidoreductase subunit F [EC:7.1.1.2] E CH54_3930 nuoG; NADH dehydrogenase (quinone), G subunit K00336 nuoG; NADH-quinone oxidoreductase subunit G [EC:7.1.1.2] E CH54_3931 NADH dehydrogenase family protein K00337 nuoH; NADH-quinone oxidoreductase subunit H [EC:7.1.1.2] E CH54_3932 NADH-quinone oxidoreductase, chain I family protein K00338 nuoI; NADH-quinone oxidoreductase subunit I [EC:7.1.1.2] E CH54_3933 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 family protein K00339 nuoJ; NADH-quinone oxidoreductase subunit J [EC:7.1.1.2] E CH54_3934 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L family protein K00340 nuoK; NADH-quinone oxidoreductase subunit K [EC:7.1.1.2] E CH54_3935 proton-translocating NADH-quinone oxidoreductase, chain L family protein K00341 nuoL; NADH-quinone oxidoreductase subunit L [EC:7.1.1.2] E CH54_3936 proton-translocating NADH-quinone oxidoreductase, chain M family protein K00342 nuoM; NADH-quinone oxidoreductase subunit M [EC:7.1.1.2] E CH54_3937 proton-translocating NADH-quinone oxidoreductase, chain N family protein K00343 nuoN; NADH-quinone oxidoreductase subunit N [EC:7.1.1.2] E CH54_3927 nuoD; NADH dehydrogenase (quinone), D subunit K13378 nuoCD; NADH-quinone oxidoreductase subunit C/D [EC:7.1.1.2] D 7.1.1.3 ubiquinol oxidase (H+-transporting) E CH54_3680 cyoA; ubiquinol oxidase, subunit II K02297 cyoA; cytochrome o ubiquinol oxidase subunit II [EC:7.1.1.3] E CH54_3679 cyoB; cytochrome o ubiquinol oxidase, subunit I K02298 cyoB; cytochrome o ubiquinol oxidase subunit I [EC:7.1.1.3] D 7.1.1.4 caldariellaquinol oxidase (H+-transporting) D 7.1.1.5 menaquinol oxidase (H+-transporting) D 7.1.1.6 plastoquinol---plastocyanin reductase D 7.1.1.7 quinol oxidase (electrogenic, proton-motive force generating) E CH54_1140 cyd operon protein YbgT K00424 cydX; cytochrome bd-I ubiquinol oxidase subunit X [EC:7.1.1.7] E CH54_1142 bacterial Cytochrome Ubiquinol Oxidase family protein K00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7] E CH54_684 bacterial Cytochrome Ubiquinol Oxidase family protein K00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7] E CH54_1141 cydB; cytochrome d ubiquinol oxidase, subunit II K00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7] E CH54_685 cydB; cytochrome d ubiquinol oxidase, subunit II K00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7] D 7.1.1.8 quinol---cytochrome-c reductase D 7.1.1.9 cytochrome-c oxidase D 7.1.1.10 ferredoxin---quinone oxidoreductase (H+-translocating) D 7.1.1.11 ferredoxin---NAD+ oxidoreductase (H+-transporting) E CH54_468 electron transport complex, RnfABCDGE type, D subunit K03614 rnfD; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit D [EC:7.1.1.11 7.2.1.2] E CH54_466 electron transport complex, RnfABCDGE type, C subunit K03615 rnfC; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit C [EC:7.1.1.11 7.2.1.2] E CH54_465 electron transport complex, RnfABCDGE type, B subunit K03616 rnfB; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit B [EC:7.1.1.11 7.2.1.2] D 7.1.1.12 succinate dehydrogenase (electrogenic, proton-motive force generating) C 7.1.2 Linked to the hydrolysis of a nucleoside triphosphate D 7.1.2.1 P-type H+-exporting transporter D 7.1.2.2 H+-transporting two-sector ATPase E CH54_2528 atpA; ATP synthase F1, alpha subunit K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1] E CH54_2526 atpD; ATP synthase F1, beta subunit K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1] C 7.1.3 Linked to the hydrolysis of diphosphate D 7.1.3.1 H+-exporting diphosphatase B 7.2 Catalysing the translocation of inorganic cations C 7.2.1 Linked to oxidoreductase reactions D 7.2.1.1 NADH:ubiquinone reductase (Na+-transporting) E CH54_3583 nqrA; ubiquinone oxidoreductase, Na(+)-translocating, A subunit K00346 nqrA; Na+-transporting NADH:ubiquinone oxidoreductase subunit A [EC:7.2.1.1] E CH54_3584 nqrB; ubiquinone oxidoreductase, Na(+)-translocating, B subunit K00347 nqrB; Na+-transporting NADH:ubiquinone oxidoreductase subunit B [EC:7.2.1.1] E CH54_3585 nqrC; ubiquinone oxidoreductase, Na(+)-translocating, C subunit K00348 nqrC; Na+-transporting NADH:ubiquinone oxidoreductase subunit C [EC:7.2.1.1] E CH54_3586 nqrD; ubiquinone oxidoreductase, Na(+)-translocating, D subunit K00349 nqrD; Na+-transporting NADH:ubiquinone oxidoreductase subunit D [EC:7.2.1.1] E CH54_3587 nqrE; ubiquinone oxidoreductase, Na(+)-translocating, E subunit K00350 nqrE; Na+-transporting NADH:ubiquinone oxidoreductase subunit E [EC:7.2.1.1] E CH54_3588 nqrF; ubiquinone oxidoreductase, Na(+)-translocating, F subunit K00351 nqrF; Na+-transporting NADH:ubiquinone oxidoreductase subunit F [EC:7.2.1.1] D 7.2.1.2 ferredoxin---NAD+ oxidoreductase (Na+-transporting) E CH54_468 electron transport complex, RnfABCDGE type, D subunit K03614 rnfD; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit D [EC:7.1.1.11 7.2.1.2] E CH54_466 electron transport complex, RnfABCDGE type, C subunit K03615 rnfC; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit C [EC:7.1.1.11 7.2.1.2] E CH54_465 electron transport complex, RnfABCDGE type, B subunit K03616 rnfB; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit B [EC:7.1.1.11 7.2.1.2] D 7.2.1.3 ascorbate ferrireductase (transmembrane) C 7.2.2 Linked to the hydrolysis of a nucleoside triphosphate D 7.2.2.1 Na+-transporting two-sector ATPase E CH54_2528 atpA; ATP synthase F1, alpha subunit K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1] E CH54_2526 atpD; ATP synthase F1, beta subunit K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1] D 7.2.2.2 ABC-type Cd2+ transporter D 7.2.2.3 P-type Na+ transporter D 7.2.2.4 ABC-type Na+ transporter D 7.2.2.5 ABC-type Mn2+ transporter D 7.2.2.6 P-type K+ transporter E CH54_1165 kdpB; K+-transporting ATPase, B subunit K01547 kdpB; potassium-transporting ATPase ATP-binding subunit [EC:7.2.2.6] D 7.2.2.7 ABC-type Fe3+ transporter E CH54_1253 ABC transporter family protein K02010 afuC; iron(III) transport system ATP-binding protein [EC:7.2.2.7] E CH54_1329 ABC transporter family protein K02010 afuC; iron(III) transport system ATP-binding protein [EC:7.2.2.7] E CH54_871 ABC transporter family protein K02010 afuC; iron(III) transport system ATP-binding protein [EC:7.2.2.7] D 7.2.2.8 P-type Cu+ transporter E CH54_3748 copper-translocating P-type ATPase K17686 copA; P-type Cu+ transporter [EC:7.2.2.8] D 7.2.2.9 P-type Cu2+ transporter D 7.2.2.10 P-type Ca2+ transporter D 7.2.2.11 ABC-type Ni2+ transporter D 7.2.2.12 P-type Zn2+ transporter E CH54_2802 cadA; cadmium-translocating P-type ATPase K01534 zntA; Zn2+/Cd2+-exporting ATPase [EC:7.2.2.12 7.2.2.21] D 7.2.2.13 Na+/K+-exchanging ATPase D 7.2.2.14 P-type Mg2+ transporter E CH54_819 mgtA; magnesium-translocating P-type ATPase K01531 mgtA; P-type Mg2+ transporter [EC:7.2.2.14] E CH54_2999 mgtA; magnesium-translocating P-type ATPase K01531 mgtA; P-type Mg2+ transporter [EC:7.2.2.14] D 7.2.2.15 P-type Ag+ transporter D 7.2.2.16 ABC-type ferric hydroxamate transporter E CH54_1723 ABC transporter family protein K10829 fhuC; ferric hydroxamate transport system ATP-binding protein [EC:7.2.2.16] D 7.2.2.17 ABC-type ferric enterobactin transporter E CH54_3169 ABC transporter family protein K23188 fepC; iron-siderophore transport system ATP-binding protein [EC:7.2.2.17 7.2.2.-] D 7.2.2.18 ABC-type ferric citrate transporter D 7.2.2.19 H+/K+-exchanging ATPase D 7.2.2.20 ABC-type Zn2+ transporter E CH54_618 ABC transporter family protein K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20] D 7.2.2.21 Cd2+-exporting ATPase E CH54_2802 cadA; cadmium-translocating P-type ATPase K01534 zntA; Zn2+/Cd2+-exporting ATPase [EC:7.2.2.12 7.2.2.21] D 7.2.2.22 P-type Mn2+ transporter C 7.2.3 D 7.2.3.1 Na+-exporting diphosphatase C 7.2.4 Linked to decarboxylation D 7.2.4.1 carboxybiotin decarboxylase D 7.2.4.2 oxaloacetate decarboxylase (Na+ extruding) D 7.2.4.3 (S)-methylmalonyl-CoA decarboxylase (sodium-transporting) D 7.2.4.4 biotin-dependent malonate decarboxylase D 7.2.4.5 glutaconyl-CoA decarboxylase B 7.3 Catalysing the translocation of inorganic anions and their chelates C 7.3.2 Linked to the hydrolysis of a nucleoside triphosphate D 7.3.2.1 ABC-type phosphate transporter E CH54_2518 pstB; phosphate ABC transporter, ATP-binding protein K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] E CH54_1358 pstB; phosphate ABC transporter, ATP-binding protein K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1] D 7.3.2.2 ABC-type phosphonate transporter E CH54_1078 phnC; phosphonate ABC transporter, ATP-binding protein K02041 phnC; phosphonate transport system ATP-binding protein [EC:7.3.2.2] D 7.3.2.3 ABC-type sulfate transporter E CH54_1301 cysA; sulfate ABC transporter, ATP-binding family protein K02045 cysA; sulfate/thiosulfate transport system ATP-binding protein [EC:7.3.2.3] D 7.3.2.4 ABC-type nitrate transporter D 7.3.2.5 ABC-type molybdate transporter E CH54_1111 modC; molybdate ABC transporter, ATP-binding protein K02017 modC; molybdate transport system ATP-binding protein [EC:7.3.2.5] D 7.3.2.6 ABC-type tungstate transporter D 7.3.2.7 arsenite-transporting ATPase B 7.4 Catalysing the translocation of amino acids and peptides C 7.4.2 Linked to the hydrolysis of a nucleoside triphosphate D 7.4.2.1 ABC-type polar-amino-acid transporter E CH54_1690 ABC transporter family protein K02028 ABC.PA.A; polar amino acid transport system ATP-binding protein [EC:7.4.2.1] E CH54_4056 ABC transporter family protein K10000 artP; arginine transport system ATP-binding protein [EC:7.4.2.1] E CH54_1205 ABC transporter family protein K10004 gltL; glutamate/aspartate transport system ATP-binding protein [EC:7.4.2.1] E CH54_758 ABC transporter family protein K10010 tcyC; L-cystine transport system ATP-binding protein [EC:7.4.2.1] E CH54_3904 ABC transporter family protein K10017 hisP; histidine transport system ATP-binding protein [EC:7.4.2.1] E CH54_1054 ABC transporter family protein K10038 glnQ; glutamine transport system ATP-binding protein [EC:7.4.2.1] D 7.4.2.2 ABC-type nonpolar-amino-acid transporter D 7.4.2.3 mitochondrial protein-transporting ATPase D 7.4.2.4 chloroplast protein-transporting ATPase D 7.4.2.5 bacterial ABC-type protein transporter D 7.4.2.6 ABC-type oligopeptide transporter D 7.4.2.7 ABC-type alpha-factor-pheromone transporter D 7.4.2.8 protein-secreting ATPase E CH54_3147 type II/IV secretion system family protein K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8] E CH54_776 fliI; flagellar protein export ATPase FliI K02412 fliI; flagellum-specific ATP synthase [EC:7.4.2.8] E CH54_3190 ATPase, FliI/YscN family protein K02412 fliI; flagellum-specific ATP synthase [EC:7.4.2.8] E CH54_3457 gspE; type II secretion system protein E K02454 gspE; general secretion pathway protein E [EC:7.4.2.8] E CH54_1770 secA; preprotein translocase, SecA subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8] E CH54_2178 ATPase, FliI/YscN family protein K03224 yscN; ATP synthase in type III secretion protein N [EC:7.4.2.8] D 7.4.2.9 ABC-type dipeptide transporter D 7.4.2.10 ABC-type glutathione transporter D 7.4.2.11 ABC-type methionine transporter D 7.4.2.12 ABC-type cystine transporter D 7.4.2.13 ABC-type tyrosine transporter D 7.4.2.14 ABC-type antigen peptide transporter B 7.5 Catalysing the translocation of carbohydrates and their derivatives C 7.5.2 Linked to the hydrolysis of a nucleoside triphosphate D 7.5.2.1 ABC-type maltose transporter D 7.5.2.2 ABC-type oligosaccharide transporter D 7.5.2.3 ABC-type beta-glucan transporter D 7.5.2.4 ABC-type teichoic-acid transporter D 7.5.2.5 ABC-type lipopolysaccharide transporter E CH54_3012 lptB; LPS export ABC transporter ATP-binding protein K06861 lptB; lipopolysaccharide export system ATP-binding protein [EC:7.5.2.5] D 7.5.2.6 ABC-type lipid A-core oligosaccharide transporter E CH54_4099 msbA; lipid A export permease/ATP-binding protein MsbA K11085 msbA; ATP-binding cassette, subfamily B, bacterial MsbA [EC:7.5.2.6] D 7.5.2.7 ABC-type D-ribose transporter E CH54_2544 ccmA; heme ABC exporter, ATP-binding protein CcmA K10441 rbsA; ribose transport system ATP-binding protein [EC:7.5.2.7] D 7.5.2.8 ABC-type D-allose transporter D 7.5.2.9 ABC-type D-galactofuranose transporter D 7.5.2.10 ABC-type D-xylose transporter E CH54_2442 ccmA; heme ABC exporter, ATP-binding protein CcmA K10545 xylG; D-xylose transport system ATP-binding protein [EC:7.5.2.10] D 7.5.2.11 ABC-type D-galactose transporter E CH54_1024 ABC transporter family protein K10542 mglA; methyl-galactoside transport system ATP-binding protein [EC:7.5.2.11] D 7.5.2.12 ABC-type L-arabinose transporter D 7.5.2.13 ABC-type D-xylose/L-arabinose transporter D 7.5.2.14 ABC-type homopolymeric O-antigen exporter B 7.6 Catalysing the translocation of other compounds C 7.6.2 Linked to the hydrolysis of a nucleoside triphosphate D 7.6.2.1 P-type phospholipid transporter D 7.6.2.2 ABC-type xenobiotic transporter D 7.6.2.3 ABC-type glutathione-S-conjugate transporter D 7.6.2.4 ABC-type fatty-acyl-CoA transporter D 7.6.2.5 ABC-type heme transporter E CH54_3846 ccmA; heme ABC exporter, ATP-binding protein CcmA K02193 ccmA; heme exporter protein A [EC:7.6.2.5] E CH54_2164 ABC transporter family protein K10834 hmuV; heme transport system ATP-binding protein [EC:7.6.2.5] D 7.6.2.6 ABC-type guanine transporter D 7.6.2.7 ABC-type taurine transporter E CH54_2276 ABC transporter family protein K10831 tauB; taurine transport system ATP-binding protein [EC:7.6.2.7] D 7.6.2.8 ABC-type vitamin B12 transporter E CH54_263 ABC transporter family protein K06074 btuD; vitamin B12 transport system ATP-binding protein [EC:7.6.2.8] D 7.6.2.9 ABC-type quaternary amine transporter E CH54_1581 proV; glycine betaine/L-proline transport ATP binding subunit K02000 proV; glycine betaine/proline transport system ATP-binding protein [EC:7.6.2.9] E CH54_1068 ABC transporter family protein K05847 opuA; osmoprotectant transport system ATP-binding protein [EC:7.6.2.9] D 7.6.2.10 ABC-type glycerol 3-phosphate transporter E CH54_2828 ABC transporter family protein K05816 ugpC; sn-glycerol 3-phosphate transport system ATP-binding protein [EC:7.6.2.10] D 7.6.2.11 ABC-type polyamine transporter D 7.6.2.12 ABC-type capsular-polysaccharide transporter D 7.6.2.13 ABC-type autoinducer-2 transporter D 7.6.2.14 ABC-type aliphatic sulfonate transporter E CH54_3296 ABC transporter family protein K15555 ssuB; sulfonate transport system ATP-binding protein [EC:7.6.2.14] D 7.6.2.15 ABC-type thiamine transporter E CH54_1808 thiQ; thiamine ABC transporter, ATP-binding protein K02062 thiQ; thiamine transport system ATP-binding protein [EC:7.6.2.15] D 7.6.2.16 ABC-type putrescine transporter E CH54_4047 polyamine ABC transporter, ATP-binding family protein K11076 potG; putrescine transport system ATP-binding protein [EC:7.6.2.16] ! #
#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 23, 2024 #
EC number data are obtained from ExplorEnz