KEGG Orthology (KO) - Apteryx mantelli mantelli (brown kiwi)

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     KO
 09100 Metabolism
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
   09131 Membrane transport
 
   09132 Signal transduction
     02020 Two-component system
     04010 MAPK signaling pathway [PATH:aam04010]
     04013 MAPK signaling pathway - fly
     04016 MAPK signaling pathway - plant
     04011 MAPK signaling pathway - yeast
     04012 ErbB signaling pathway [PATH:aam04012]
       106491937 EGF; epidermal growth factor
       106490250 TGFA; transforming growth factor alpha
       106491797 AREG; amphiregulin
       106495273 EGFR; epidermal growth factor receptor
       106486153 ERBB2; erb-b2 receptor tyrosine kinase 2
       106494802 1-phosphatidylinositol 4
       106488145 PLCG1; phospholipase C gamma 1
       106483269 PLCG2; phospholipase C gamma 2
       106491995 CAMK2D; calcium/calmodulin dependent protein kinase II delta
       106493448 CAMK2A; calcium/calmodulin dependent protein kinase II alpha
       106494574 CAMK2B; calcium/calmodulin dependent protein kinase II beta
       106498878 CAMK2G; calcium/calmodulin dependent protein kinase II gamma
       106493092 PRKCA; protein kinase C alpha
       106486190 PRKCB; protein kinase C beta
       106495869 CBL; Cbl proto-oncogene
       106490686 CBLB; Cbl proto-oncogene B
       106493368 proto-oncogene tyrosine-protein kinase Src
       106482268 focal adhesion kinase 1
       106487715 CRK; CRK proto-oncogene, adaptor protein
       106486247 CRKL; CRK like proto-oncogene, adaptor protein
       106486072 ABL1; ABL proto-oncogene 1, non-receptor tyrosine kinase
       106484954 ABL2; ABL proto-oncogene 2, non-receptor tyrosine kinase
       106494037 NCK2; NCK adaptor protein 2
       106495371 PAK1; p21 (RAC1) activated kinase 1
       106492613 PAK2; p21 (RAC1) activated kinase 2
       106494786 PAK3; p21 (RAC1) activated kinase 3
       106490395 PAK5; p21 (RAC1) activated kinase 5
       106486712 PAK6; p21 (RAC1) activated kinase 6
       106496868 MAP2K4; mitogen-activated protein kinase kinase 4
       106493457 MAPK9; mitogen-activated protein kinase 9
       106496655 MAPK10; mitogen-activated protein kinase 10
       106497812 MAPK8; mitogen-activated protein kinase 8
       106494500 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
       106495339 probetacellulin-like
       106495340 probetacellulin-like
       106494293 HBEGF; heparin binding EGF like growth factor
       106491798 EREG; epiregulin
       106482511 NRG1; neuregulin 1
       106494304 NRG2; neuregulin 2
       106492330 ERBB4; erb-b2 receptor tyrosine kinase 4
       106483710 SHC-transforming protein 1-like
       106486386 SHC2; SHC adaptor protein 2
       106495478 SHC3; SHC adaptor protein 3
       106496580 SHC4; SHC adaptor protein 4
       106485676 GRB2; growth factor receptor bound protein 2
       106495130 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
       106499697 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
       106494862 HRAS; HRas proto-oncogene, GTPase
       106488640 KRAS; KRAS proto-oncogene, GTPase
       106485268 NRAS; neuroblastoma RAS viral oncogene homolog
       106488842 BRAF; B-Raf proto-oncogene, serine/threonine kinase
       106488826 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
       106487663 MAP2K1; mitogen-activated protein kinase kinase 1
       106492199 MAP2K2; mitogen-activated protein kinase kinase 2
       106486864 MAPK1; mitogen-activated protein kinase 1
       106496220 MYC; v-myc avian myelocytomatosis viral oncogene homolog
       106492079 GAB1; GRB2 associated binding protein 1
       106499852 NRG3; neuregulin 3
       106496531 NRG4; neuregulin 4
       106496183 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       106499152 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       106482245 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       106499441 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
       106485939 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
       106495610 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
       106485509 AKT3; AKT serine/threonine kinase 3
       106493726 AKT2; AKT serine/threonine kinase 2
       106482997 AKT1; AKT serine/threonine kinase 1
       106482444 MTOR; mechanistic target of rapamycin
       106492594 ribosomal protein S6 kinase beta-2-like
       106500339 RPS6KB1; ribosomal protein S6 kinase B1
       106497256 GSK3B; glycogen synthase kinase 3 beta
       106488961 CDKN1B; cyclin dependent kinase inhibitor 1B
       106484396 CDKN1A; cyclin dependent kinase inhibitor 1A
       106488969 cyclin-dependent kinase inhibitor 1-like
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K09782 AREG; amphiregulin
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K22517 CBLB; E3 ubiquitin-protein ligase CBL-B [EC:2.3.2.27]
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K08887 ABL2; abelson tyrosine-protein kinase 2 [EC:2.7.10.2]
K19862 NCK2; NCK adaptor protein 2
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3; p21-activated kinase 3 [EC:2.7.11.1]
K05736 PAK5; p21-activated kinase 5 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K04430 MAP2K4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K09783 BTC; betacellulin
K09783 BTC; betacellulin
K08523 HBEGF; heparin-binding EGF-like growth factor
K09784 EREG; epiregulin
K05455 NRG1; neuregulin 1
K05456 NRG2; neuregulin 2
K05085 ERBB4; receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04377 MYC; Myc proto-oncogene protein
K09593 GAB1; GRB2-associated-binding protein 1
K05457 NRG3; neuregulin 3
K05458 NRG4; neuregulin 4
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
     04014 Ras signaling pathway
     04015 Rap1 signaling pathway
     04310 Wnt signaling pathway [PATH:aam04310]
     04330 Notch signaling pathway [PATH:aam04330]
     04340 Hedgehog signaling pathway [PATH:aam04340]
     04341 Hedgehog signaling pathway - fly
     04350 TGF-beta signaling pathway [PATH:aam04350]
     04390 Hippo signaling pathway
     04391 Hippo signaling pathway - fly
     04392 Hippo signaling pathway - multiple species
     04370 VEGF signaling pathway [PATH:aam04370]
     04371 Apelin signaling pathway [PATH:aam04371]
     04630 JAK-STAT signaling pathway
     04064 NF-kappa B signaling pathway
     04668 TNF signaling pathway
     04066 HIF-1 signaling pathway
     04068 FoxO signaling pathway [PATH:aam04068]
       106490440 TGFB2; transforming growth factor beta 2
       106482877 TGFB3; transforming growth factor beta 3
       106491015 TGFBR1; transforming growth factor beta receptor 1
       106491249 TGFBR2; transforming growth factor beta receptor 2
       106498480 TGF-beta receptor type-2-like
       106494875 SMAD4; SMAD family member 4
       106493536 STK11; serine/threonine kinase 11
       106499548 PRKAA1; protein kinase AMP-activated catalytic subunit alpha 1
       106499832 5'-AMP-activated protein kinase catalytic subunit alpha-2-like
       106498958 PRKAA2; protein kinase AMP-activated catalytic subunit alpha 2
       106499653 PRKAB2; protein kinase AMP-activated non-catalytic subunit beta 2
       106486336 PRKAB1; protein kinase AMP-activated non-catalytic subunit beta 1
       106497509 PRKAG1; protein kinase AMP-activated non-catalytic subunit gamma 1
       106499071 5'-AMP-activated protein kinase subunit gamma-3-like
       106499072 PRKAG3; protein kinase AMP-activated non-catalytic subunit gamma 3
       106490284 PRKAG2; protein kinase AMP-activated non-catalytic subunit gamma 2
       106498756 NLK; nemo like kinase
       106499538 SKP2; S-phase kinase associated protein 2
       106488755 MDM2; MDM2 proto-oncogene
       106491857 SETD7; SET domain containing lysine methyltransferase 7
       106482329 CREBBP; CREB binding protein
       106488223 histone acetyltransferase p300-like
       106486965 SIRT1; sirtuin 1
       106482615 USP7; ubiquitin specific peptidase 7
       106493457 MAPK9; mitogen-activated protein kinase 9
       106496655 MAPK10; mitogen-activated protein kinase 10
       106497812 MAPK8; mitogen-activated protein kinase 8
       106500122 STK4; serine/threonine kinase 4
       106488383 IGF1; insulin like growth factor 1
       106485327 IGF1R; insulin like growth factor 1 receptor
       106497062 INS; insulin
       106495607 INSR; insulin receptor
       106485843 IRS1; insulin receptor substrate 1
       106482668 insulin receptor substrate 2-B-like
       106482669 insulin receptor substrate 2-B-like
       106493916 IRS2; insulin receptor substrate 2
       106496183 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       106499152 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       106482245 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       106499441 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
       106485939 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
       106495610 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
       106486128 PDPK1; 3-phosphoinositide dependent protein kinase 1
       106495295 CHUK; conserved helix-loop-helix ubiquitous kinase
       106487776 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
       106495308 PTEN; phosphatase and tensin homolog
       106485509 AKT3; AKT serine/threonine kinase 3
       106493726 AKT2; AKT serine/threonine kinase 2
       106482997 AKT1; AKT serine/threonine kinase 1
       106498005 SGK1; serum/glucocorticoid regulated kinase 1
       106488186 SGK2; SGK2, serine/threonine kinase 2
       106484648 serine/threonine-protein kinase Sgk3
       106489240 FOXO1; forkhead box O1
       106489614 FOXO3; forkhead box O3
       106487868 FOXO4; forkhead box O4
       106484709 FOXO6; forkhead box O6
       106486778 GRM1; glutamate metabotropic receptor 1
       106496539 HOMER2; homer scaffolding protein 2
       106494798 HOMER3; homer scaffolding protein 3
       106496718 HOMER1; homer scaffolding protein 1
       106488733 casein kinase I isoform epsilon
       106483538 IL6; interleukin 6
       106495801 IL10; interleukin 10
       106491102 STAT3; signal transducer and activator of transcription 3
       106491937 EGF; epidermal growth factor
       106495273 EGFR; epidermal growth factor receptor
       106485676 GRB2; growth factor receptor bound protein 2
       106495130 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
       106499697 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
       106494862 HRAS; HRas proto-oncogene, GTPase
       106488640 KRAS; KRAS proto-oncogene, GTPase
       106485268 NRAS; neuroblastoma RAS viral oncogene homolog
       106488842 BRAF; B-Raf proto-oncogene, serine/threonine kinase
       106488826 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
       106487663 MAP2K1; mitogen-activated protein kinase kinase 1
       106492199 MAP2K2; mitogen-activated protein kinase kinase 2
       106486864 MAPK1; mitogen-activated protein kinase 1
       106487858 MAPK13; mitogen-activated protein kinase 13
       106487877 MAPK14; mitogen-activated protein kinase 14
       106495922 MAPK12; mitogen-activated protein kinase 12
       106495935 MAPK11; mitogen-activated protein kinase 11
       106482119 CDK2; cyclin dependent kinase 2
       106483149 FOXG1; forkhead box G1
       106484407 G2/mitotic-specific cyclin-B1-like
       106497404 CCNB3; cyclin B3
       106498229 CCND1; cyclin D1
       106489562 CCND2; cyclin D2
       106492130 CCNG2; cyclin G2
       106484396 CDKN1A; cyclin dependent kinase inhibitor 1A
       106488969 cyclin-dependent kinase inhibitor 1-like
       106488961 CDKN1B; cyclin dependent kinase inhibitor 1B
       106483200 RBL2; RB transcriptional corepressor like 2
       106486200 PLK1; polo like kinase 1
       106500310 PLK3; polo like kinase 3
       106492025 PLK4; polo like kinase 4
       106483968 growth arrest and DNA damage-inducible protein GADD45 beta-like
       106500154 growth arrest and DNA damage-inducible protein GADD45 gamma-like
       106499359 GADD45G; growth arrest and DNA damage inducible gamma
       106499698 FASLG; Fas ligand
       106494355 BCL2L11; BCL2 like 11
       106486566 TNFSF10; tumor necrosis factor superfamily member 10
       106498231 BCL6; B-cell CLL/lymphoma 6
       106489254 BNIP3; BCL2 interacting protein 3
       106497285 GABARAPL1; GABA type A receptor associated protein like 1
       106498800 GABARAPL2; GABA type A receptor associated protein like 2
       106498301 CAT; catalase
       106486808 SOD2; superoxide dismutase 2
       106493490 ATM; ATM serine/threonine kinase
       106491741 PCK1; phosphoenolpyruvate carboxykinase 1
       106484949 phosphoenolpyruvate carboxykinase [GTP]
       106485031 G6PC3; glucose-6-phosphatase catalytic subunit 3
       106491767 G6PC; glucose-6-phosphatase catalytic subunit
       106499300 G6PC2; glucose-6-phosphatase catalytic subunit 2
       106499523 IL7R; interleukin 7 receptor
       106495614 KLF2; Kruppel like factor 2
       106499742 S1PR1; sphingosine-1-phosphate receptor 1
       106486399 S1PR4; sphingosine-1-phosphate receptor 4
       106498195 RAG1; recombination activating 1
       106498365 RAG2; recombination activating 2
       106486686 FBXO25; F-box protein 25
       106496302 FBXO32; F-box protein 32
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04501 SMAD4; mothers against decapentaplegic homolog 4
K07298 STK11; serine/threonine-protein kinase 11 [EC:2.7.11.1]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K04468 NLK; nemo like kinase [EC:2.7.11.24]
K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K11431 SETD7; [histone H3]-lysine4 N-methyltransferase [EC:2.1.1.364]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K11411 SIRT1; NAD+-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04411 STK4; serine/threonine kinase 4
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04526 INS; insulin
K04527 INSR; insulin receptor [EC:2.7.10.1]
K16172 IRS1; insulin receptor substrate 1
K07187 IRS2; insulin receptor substrate 2
K07187 IRS2; insulin receptor substrate 2
K07187 IRS2; insulin receptor substrate 2
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K13302 SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
K13303 SGK2; serum/glucocorticoid-regulated kinase 2 [EC:2.7.11.1]
K13304 SGK3; serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1]
K07201 FOXO1; forkhead box protein O1
K09408 FOXO3; forkhead box protein O3
K12358 FOXO4; forkhead box protein O4
K17847 FOXO6; forkhead box protein O6
K04603 GRM1; metabotropic glutamate receptor 1
K15010 HOMER; homer
K15010 HOMER; homer
K15010 HOMER; homer
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K05405 IL6; interleukin 6
K05443 IL10; interleukin 10
K04692 STAT3; signal transducer and activator of transcription 3
K04357 EGF; epidermal growth factor
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K09385 FOXG; forkhead box protein G
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21771 CCNB3; G2/mitotic-specific cyclin-B3
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10146 CCNG2; cyclin G2
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K16332 RBL2; retinoblastoma-like protein 2
K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
K08862 PLK3; polo-like kinase 3 [EC:2.7.11.21]
K08863 PLK4; polo-like kinase 4 [EC:2.7.11.21]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K16341 BCL2L11; Bcl-2-like protein 11
K04721 TNFSF10; tumor necrosis factor ligand superfamily member 10
K15618 BCL6; B-cell lymphoma 6 protein
K15464 BNIP3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
K08341 GABARAP; GABA(A) receptor-associated protein
K08341 GABARAP; GABA(A) receptor-associated protein
K03781 katE; catalase [EC:1.11.1.6]
K04564 SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K05072 IL7R; interleukin 7 receptor
K17845 KLF2; krueppel-like factor 2
K04288 S1PR1; sphingosine 1-phosphate receptor 1
K04293 S1PR4; sphingosine 1-phosphate receptor 4
K10628 RAG1; V(D)J recombination-activating protein 1 [EC:2.3.2.27]
K10988 RAG2; recombination-activating protein 2
K10305 FBXO25_32; F-box protein 25/32
K10305 FBXO25_32; F-box protein 25/32
     04020 Calcium signaling pathway [PATH:aam04020]
     04070 Phosphatidylinositol signaling system [PATH:aam04070]
     04072 Phospholipase D signaling pathway
     04071 Sphingolipid signaling pathway
     04024 cAMP signaling pathway
     04022 cGMP-PKG signaling pathway
     04151 PI3K-Akt signaling pathway
     04152 AMPK signaling pathway
     04150 mTOR signaling pathway [PATH:aam04150]
     04075 Plant hormone signal transduction
 
   09133 Signaling molecules and interaction
 
 09140 Cellular Processes
 
   09141 Transport and catabolism
 
   09143 Cell growth and death
     04110 Cell cycle [PATH:aam04110]
       106498229 CCND1; cyclin D1
       106489562 CCND2; cyclin D2
       106483949 CCND3; cyclin D3
       106492770 cyclin-dependent kinase 4-like
       106483627 CDK6; cyclin dependent kinase 6
       106489167 RB1; RB transcriptional corepressor 1
       106499916 RBL1; RB transcriptional corepressor like 1
       106483200 RBL2; RB transcriptional corepressor like 2
       106486072 ABL1; ABL proto-oncogene 1, non-receptor tyrosine kinase
       106493331 HDAC1; histone deacetylase 1
       106489693 HDAC2; histone deacetylase 2
       106496602 E2F1; E2F transcription factor 1
       106486140 E2F2; E2F transcription factor 2
       106500319 E2F3; E2F transcription factor 3
       106496261 E2F5; E2F transcription factor 5
       106484508 E2F4; E2F transcription factor 4
       106494055 TFDP1; transcription factor Dp-1
       106485889 TFDP2; transcription factor Dp-2
       106497256 GSK3B; glycogen synthase kinase 3 beta
       106490440 TGFB2; transforming growth factor beta 2
       106482877 TGFB3; transforming growth factor beta 3
       106497650 SMAD2; SMAD family member 2
       106494875 SMAD4; SMAD family member 4
       106496220 MYC; v-myc avian myelocytomatosis viral oncogene homolog
       106491387 ZBTB17; zinc finger and BTB domain containing 17
       106491607 CDKN2C; cyclin dependent kinase inhibitor 2C
       106488961 CDKN1B; cyclin dependent kinase inhibitor 1B
       106484396 CDKN1A; cyclin dependent kinase inhibitor 1A
       106488969 cyclin-dependent kinase inhibitor 1-like
       106483881 CCNE2; cyclin E2
       106483300 CCNE1; cyclin E1
       106482119 CDK2; cyclin dependent kinase 2
       106487187 SKP1; S-phase kinase associated protein 1
       106495275 CUL1; cullin 1
       106488968 RBX1; ring-box 1
       106499538 SKP2; S-phase kinase associated protein 2
       106500420 CCNA1; cyclin A1
       106492064 CCNA2; cyclin A2
       106486420 CDC6; cell division cycle 6
       106486844 CDC45; cell division cycle 45
       106499794 CDC7; cell division cycle 7
       106483609 DBF4; DBF4 zinc finger
       106486975 CDK1; cyclin dependent kinase 1
       106484407 G2/mitotic-specific cyclin-B1-like
       106497404 CCNB3; cyclin B3
       106487512 M-phase inducer phosphatase 2-like
       106487224 CDC25C; cell division cycle 25C
       106483898 YWHAZ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
       106494747 YWHAQ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
       106500151 YWHAB; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
       106487710 YWHAE; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
       106497328 YWHAG; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
       106486310 YWHAH; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
       106486200 PLK1; polo like kinase 1
       106488273 WEE2; WEE1 homolog 2
       106497137 WEE1; WEE1 G2 checkpoint kinase
       106486565 CDK7; cyclin dependent kinase 7
       106499348 ANAPC1; anaphase promoting complex subunit 1
       106493037 ANAPC2; anaphase promoting complex subunit 2
       106497413 CDC27; cell division cycle 27
       106498734 ANAPC4; anaphase promoting complex subunit 4
       106497652 anaphase-promoting complex subunit 5
       106493944 CDC16; cell division cycle 16
       106497691 ANAPC7; anaphase promoting complex subunit 7
       106487237 CDC23; cell division cycle 23
       106492140 ANAPC10; anaphase promoting complex subunit 10
       106493015 CDC26; cell division cycle 26
       106493189 ANAPC13; anaphase promoting complex subunit 13
       106499449 CDC20; cell division cycle 20
       106493602 PTTG1; pituitary tumor-transforming 1
       106488008 ESPL1; extra spindle pole bodies like 1, separase
       106488571 SMC1B; structural maintenance of chromosomes 1B
       106495393 SMC3; structural maintenance of chromosomes 3
       106485692 STAG1; stromal antigen 1
       106491237 cohesin subunit SA-2-like
       106487565 STAG2; stromal antigen 2
       106496308 RAD21; RAD21 cohesin complex component
       106493226 RAD21L1; RAD21 cohesin complex component like 1
       106489724 TTK; TTK protein kinase
       106494262 BUB1; BUB1 mitotic checkpoint serine/threonine kinase
       106494203 BUB3; BUB3, mitotic checkpoint protein
       106486730 BUB1B; BUB1 mitotic checkpoint serine/threonine kinase B
       106499960 MAD1L1; MAD1 mitotic arrest deficient like 1
       106491842 MAD2L1; MAD2 mitotic arrest deficient-like 1 (yeast)
       106482441 MAD2L2; MAD2 mitotic arrest deficient-like 2 (yeast)
       106486014 FZR1; fizzy/cell division cycle 20 related 1
       106486837 dual specificity protein phosphatase CDC14B-like
       106493168 dual specificity protein phosphatase CDC14B-like
       106499545 CDC14A; cell division cycle 14A
       106483392 dual specificity protein phosphatase CDC14B-like
       106485832 ATR; ATR serine/threonine kinase
       106493490 ATM; ATM serine/threonine kinase
       106492744 CHEK2; checkpoint kinase 2
       106482329 CREBBP; CREB binding protein
       106488223 histone acetyltransferase p300-like
       106494392 PRKDC; protein kinase, DNA-activated, catalytic polypeptide
       106488755 MDM2; MDM2 proto-oncogene
       106483968 growth arrest and DNA damage-inducible protein GADD45 beta-like
       106500154 growth arrest and DNA damage-inducible protein GADD45 gamma-like
       106499359 GADD45G; growth arrest and DNA damage inducible gamma
       106485590 SFN; stratifin
       106499367 M-phase inducer phosphatase 1-like
       106491085 ORC1; origin recognition complex subunit 1
       106492459 ORC2; origin recognition complex subunit 2
       106489666 ORC3; origin recognition complex subunit 3
       106498517 ORC4; origin recognition complex subunit 4
       106485867 ORC5; origin recognition complex subunit 5
       106483218 ORC6; origin recognition complex subunit 6
       106482774 MCM2; minichromosome maintenance complex component 2
       106500523 MCM3; minichromosome maintenance complex component 3
       106494391 MCM4; minichromosome maintenance complex component 4
       106488827 MCM5; minichromosome maintenance complex component 5
       106498425 MCM6; minichromosome maintenance complex component 6
       106484790 MCM7; minichromosome maintenance complex component 7
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K04681 RBL1; retinoblastoma-like protein 1
K16332 RBL2; retinoblastoma-like protein 2
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04682 E2F4_5; transcription factor E2F4/5
K04682 E2F4_5; transcription factor E2F4/5
K04683 TFDP1; transcription factor Dp-1
K09392 TFDP2; transcription factor Dp-2
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04500 SMAD2; mothers against decapentaplegic homolog 2
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04377 MYC; Myc proto-oncogene protein
K10500 ZBTB17; zinc finger and BTB domain-containing protein 17
K06622 CDKN2C; cyclin-dependent kinase inhibitor 2C
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K03094 SKP1; S-phase kinase-associated protein 1
K03347 CUL1; cullin 1
K03868 RBX1; RING-box protein 1 [EC:2.3.2.32]
K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K02213 CDC6; cell division control protein 6
K06628 CDC45; cell division control protein 45
K02214 CDC7; cell division control protein 7 [EC:2.7.11.1]
K06629 ASK; activator of S phase kinase
K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21771 CCNB3; G2/mitotic-specific cyclin-B3
K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
K05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K06630 YWHAE; 14-3-3 protein epsilon
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
K03348 APC1; anaphase-promoting complex subunit 1
K03349 APC2; anaphase-promoting complex subunit 2
K03350 APC3; anaphase-promoting complex subunit 3
K03351 APC4; anaphase-promoting complex subunit 4
K03352 APC5; anaphase-promoting complex subunit 5
K03353 APC6; anaphase-promoting complex subunit 6
K03354 APC7; anaphase-promoting complex subunit 7
K03355 APC8; anaphase-promoting complex subunit 8
K03357 APC10; anaphase-promoting complex subunit 10
K03359 APC12; anaphase-promoting complex subunit 12
K12456 APC13; anaphase-promoting complex subunit 13
K03363 CDC20; cell division cycle 20, cofactor of APC complex
K06635 PTTG; securin
K02365 ESP1; separase [EC:3.4.22.49]
K06636 SMC1; structural maintenance of chromosome 1
K06669 SMC3; structural maintenance of chromosome 3 (chondroitin sulfate proteoglycan 6)
K06671 STAG1_2; cohesin complex subunit SA-1/2
K06671 STAG1_2; cohesin complex subunit SA-1/2
K06671 STAG1_2; cohesin complex subunit SA-1/2
K06670 SCC1; cohesin complex subunit SCC1
K06670 SCC1; cohesin complex subunit SCC1
K08866 TTK; serine/threonine-protein kinase TTK/MPS1 [EC:2.7.12.1]
K02178 BUB1; checkpoint serine/threonine-protein kinase [EC:2.7.11.1]
K02180 BUB3; cell cycle arrest protein BUB3
K06637 BUB1B; mitotic checkpoint serine/threonine-protein kinase BUB1 beta [EC:2.7.11.1]
K06679 MAD1; mitotic spindle assembly checkpoint protein MAD1
K02537 MAD2; mitotic spindle assembly checkpoint protein MAD2
K13728 MAD2L2; mitotic spindle assembly checkpoint protein MAD2B
K03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
K06639 CDC14; cell division cycle 14 [EC:3.1.3.16 3.1.3.48]
K06639 CDC14; cell division cycle 14 [EC:3.1.3.16 3.1.3.48]
K06639 CDC14; cell division cycle 14 [EC:3.1.3.16 3.1.3.48]
K06639 CDC14; cell division cycle 14 [EC:3.1.3.16 3.1.3.48]
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K06644 SFN; stratifin
K06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
K02603 ORC1; origin recognition complex subunit 1
K02604 ORC2; origin recognition complex subunit 2
K02605 ORC3; origin recognition complex subunit 3
K02606 ORC4; origin recognition complex subunit 4
K02607 ORC5; origin recognition complex subunit 5
K02608 ORC6; origin recognition complex subunit 6
K02540 MCM2; DNA replication licensing factor MCM2 [EC:3.6.4.12]
K02541 MCM3; DNA replication licensing factor MCM3 [EC:3.6.4.12]
K02212 MCM4; DNA replication licensing factor MCM4 [EC:3.6.4.12]
K02209 MCM5; DNA replication licensing factor MCM5 [EC:3.6.4.12]
K02542 MCM6; DNA replication licensing factor MCM6 [EC:3.6.4.12]
K02210 MCM7; DNA replication licensing factor MCM7 [EC:3.6.4.12]
     04111 Cell cycle - yeast
     04112 Cell cycle - Caulobacter
     04113 Meiosis - yeast
     04114 Oocyte meiosis [PATH:aam04114]
     04210 Apoptosis [PATH:aam04210]
     04214 Apoptosis - fly
     04215 Apoptosis - multiple species
     04216 Ferroptosis [PATH:aam04216]
     04217 Necroptosis [PATH:aam04217]
     04115 p53 signaling pathway [PATH:aam04115]
       106493490 ATM; ATM serine/threonine kinase
       106492744 CHEK2; checkpoint kinase 2
       106485832 ATR; ATR serine/threonine kinase
       106499206 GORAB; golgin, RAB6 interacting
       106488755 MDM2; MDM2 proto-oncogene
       106484871 MDM4; MDM4, p53 regulator
       106484396 CDKN1A; cyclin dependent kinase inhibitor 1A
       106488969 cyclin-dependent kinase inhibitor 1-like
       106498229 CCND1; cyclin D1
       106489562 CCND2; cyclin D2
       106483949 CCND3; cyclin D3
       106492770 cyclin-dependent kinase 4-like
       106483627 CDK6; cyclin dependent kinase 6
       106483881 CCNE2; cyclin E2
       106483300 CCNE1; cyclin E1
       106482119 CDK2; cyclin dependent kinase 2
       106485590 SFN; stratifin
       106484407 G2/mitotic-specific cyclin-B1-like
       106486975 CDK1; cyclin dependent kinase 1
       106483968 growth arrest and DNA damage-inducible protein GADD45 beta-like
       106500154 growth arrest and DNA damage-inducible protein GADD45 gamma-like
       106499359 GADD45G; growth arrest and DNA damage inducible gamma
       106487759 GTSE1; G2 and S-phase expressed 1
       106487830 FAS; Fas cell surface death receptor
       106489998 PIDD1; p53-induced death domain protein 1
       106485705 tumor necrosis factor receptor superfamily member 10A-like
       106496997 uncharacterized LOC106496997
       106492412 caspase-8-like
       106492473 CASP8; caspase 8
       106488953 BID; BH3 interacting domain death agonist
       106499501 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
       106497383 BCL2L1; BCL2 like 1
       106482986 BCL2; BCL2, apoptosis regulator
       106496298 quinone oxidoreductase PIG3-like
       106496448 quinone oxidoreductase PIG3-like
       106498503 EI24; EI24, autophagy associated transmembrane protein
       106486670 SHISA5; shisa family member 5
       106497919 p53 apoptosis effector related to PMP-22-like
       106498039 p53 apoptosis effector related to PMP-22-like
       106482244 ZMAT3; zinc finger matrin-type 3
       106483212 SIAH1; siah E3 ubiquitin protein ligase 1
       106483447 cytochrome c
       106488625 APAF1; apoptotic peptidase activating factor 1
       106493414 CASP9; caspase 9
       106484082 CASP3; caspase 3
       106484243 AIFM2; apoptosis inducing factor, mitochondria associated 2
       106492834 IGFBP3; insulin like growth factor binding protein 3
       106488383 IGF1; insulin like growth factor 1
       106498280 CD82; CD82 molecule
       106482797 THBS1; thrombospondin 1
       106482655 SERPINB5; serpin family B member 5
       106498364 DDB2; damage specific DNA binding protein 2
       106483902 RRM2B; ribonucleotide reductase regulatory TP53 inducible subunit M2B
       106494774 RRM2; ribonucleotide reductase regulatory subunit M2
       106495519 SESN3; sestrin 3
       106487861 IL2RG; interleukin 2 receptor subunit gamma
       106489671 SESN1; sestrin 1
       106486144 SESN2; sestrin 2
       106495308 PTEN; phosphatase and tensin homolog
       106492227 TSC2; tuberous sclerosis 2
       106498483 STEAP3; STEAP3 metalloreductase
       106500095 RFWD2; ring finger and WD repeat domain 2
       106495341 RCHY1; ring finger and CHY zinc finger domain containing 1
       106493640 cyclin-G1-like
       106492130 CCNG2; cyclin G2
       106495868 PPM1D; protein phosphatase, Mg2+/Mn2+ dependent 1D
       106485729 TP73; tumor protein p73
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K19748 GORAB; RAB6-interacting golgin
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K10127 MDM4; protein Mdm4
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06644 SFN; stratifin
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K10129 GTSE1; G-2 and S-phase expressed protein 1
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K10130 LRDD; leucine-rich repeats and death domain-containing protein
K04722 TNFRSF10A_B; tumor necrosis factor receptor superfamily member 10A/B
K04722 TNFRSF10A_B; tumor necrosis factor receptor superfamily member 10A/B
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K10131 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator Bcl-2
K10133 TP53I3; tumor protein p53-inducible protein 3 [EC:1.-.-.-]
K10133 TP53I3; tumor protein p53-inducible protein 3 [EC:1.-.-.-]
K10134 EI24; etoposide-induced 2.4 mRNA
K10135 SCOTIN; scotin
K10136 PERP; TP53 apoptosis effector
K10136 PERP; TP53 apoptosis effector
K10137 ZMAT3; zinc finger, matrin type 3
K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K22745 AIFM2; apoptosis-inducing factor 2
K10138 IGFBP3; insulin-like growth factor-binding protein 3
K05459 IGF1; insulin-like growth factor 1
K06509 KAI1; CD82 antigen
K16857 THBS1; thrombospondin 1
K10139 SERPINB5; serpin B5
K10140 DDB2; DNA damage-binding protein 2
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K10141 SESN1_3; sestrin 1/3
K10141 SESN1_3; sestrin 1/3
K10141 SESN1_3; sestrin 1/3
K20394 SESN2; sestrin 2
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K07207 TSC2; tuberous sclerosis 2
K10142 STEAP3; metalloreductase STEAP3 [EC:1.16.1.-]
K10143 RFWD2; E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]
K10144 RCHY1; RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]
K10145 CCNG1; cyclin G1
K10146 CCNG2; cyclin G2
K10147 PPM1D; protein phosphatase 1D [EC:3.1.3.16]
K10148 TP73; tumor protein p73
     04218 Cellular senescence [PATH:aam04218]
       106490440 TGFB2; transforming growth factor beta 2
       106482877 TGFB3; transforming growth factor beta 3
       106491015 TGFBR1; transforming growth factor beta receptor 1
       106491249 TGFBR2; transforming growth factor beta receptor 2
       106498480 TGF-beta receptor type-2-like
       106497650 SMAD2; SMAD family member 2
       106492770 cyclin-dependent kinase 4-like
       106483627 CDK6; cyclin dependent kinase 6
       106498229 CCND1; cyclin D1
       106489562 CCND2; cyclin D2
       106483949 CCND3; cyclin D3
       106489167 RB1; RB transcriptional corepressor 1
       106499916 RBL1; RB transcriptional corepressor like 1
       106483200 RBL2; RB transcriptional corepressor like 2
       106496602 E2F1; E2F transcription factor 1
       106486140 E2F2; E2F transcription factor 2
       106500319 E2F3; E2F transcription factor 3
       106496261 E2F5; E2F transcription factor 5
       106484508 E2F4; E2F transcription factor 4
       106496183 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       106499152 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       106482245 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       106499441 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
       106485939 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
       106495610 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
       106489240 FOXO1; forkhead box O1
       106489614 FOXO3; forkhead box O3
       106484396 CDKN1A; cyclin dependent kinase inhibitor 1A
       106488969 cyclin-dependent kinase inhibitor 1-like
       106482119 CDK2; cyclin dependent kinase 2
       106483881 CCNE2; cyclin E2
       106483300 CCNE1; cyclin E1
       106489919 class I histocompatibility antigen
       106496148 class I histocompatibility antigen
       106497303 class I histocompatibility antigen
       106492643 class I histocompatibility antigen
       106496679 class I histocompatibility antigen
       106497304 class I histocompatibility antigen
       106488640 KRAS; KRAS proto-oncogene, GTPase
       106485268 NRAS; neuroblastoma RAS viral oncogene homolog
       106497122 RRAS2; related RAS viral (r-ras) oncogene homolog 2
       106499141 MRAS; muscle RAS oncogene homolog
       106494862 HRAS; HRas proto-oncogene, GTPase
       106485509 AKT3; AKT serine/threonine kinase 3
       106493726 AKT2; AKT serine/threonine kinase 2
       106482997 AKT1; AKT serine/threonine kinase 1
       106483762 TSC1; tuberous sclerosis 1
       106492227 TSC2; tuberous sclerosis 2
       106490276 RHEB; Ras homolog enriched in brain
       106482444 MTOR; mechanistic target of rapamycin
       106495308 PTEN; phosphatase and tensin homolog
       106486965 SIRT1; sirtuin 1
       106500420 CCNA1; cyclin A1
       106492064 CCNA2; cyclin A2
       106488197 MYBL2; MYB proto-oncogene like 2
       106482716 LIN9; lin-9 DREAM MuvB core complex component
       106483045 LIN52; lin-52 DREAM MuvB core complex component
       106496667 LIN54; lin-54 DREAM MuvB core complex component
       106493323 RBBP4; RB binding protein 4, chromatin remodeling factor
       106495734 FOXM1; forkhead box M1
       106496220 MYC; v-myc avian myelocytomatosis viral oncogene homolog
       106488755 MDM2; MDM2 proto-oncogene
       106495799 RASSF5; Ras association domain family member 5
       106484672 BTRC; beta-transducin repeat containing E3 ubiquitin protein ligase
       106488073 FBXW11; F-box and WD repeat domain containing 11
       106485266 HIPK1; homeodomain interacting protein kinase 1
       106497104 HIPK3; homeodomain interacting protein kinase 3
       106493722 HIPK4; homeodomain interacting protein kinase 4
       106488601 homeodomain-interacting protein kinase 2
       106495691 PPP1CC; protein phosphatase 1 catalytic subunit gamma
       106495808 serine/threonine-protein phosphatase alpha-3 isoform-like
       106485498 PPP1CB; protein phosphatase 1 catalytic subunit beta
       106488826 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
       106487663 MAP2K1; mitogen-activated protein kinase kinase 1
       106492199 MAP2K2; mitogen-activated protein kinase kinase 2
       106486864 MAPK1; mitogen-activated protein kinase 1
       106499937 ETS1; ETS proto-oncogene 1, transcription factor
       106486833 dual specificity mitogen-activated protein kinase kinase 3
       106490233 MAP2K6; mitogen-activated protein kinase kinase 6
       106487858 MAPK13; mitogen-activated protein kinase 13
       106487877 MAPK14; mitogen-activated protein kinase 14
       106495922 MAPK12; mitogen-activated protein kinase 12
       106495935 MAPK11; mitogen-activated protein kinase 11
       106483968 growth arrest and DNA damage-inducible protein GADD45 beta-like
       106500154 growth arrest and DNA damage-inducible protein GADD45 gamma-like
       106499359 GADD45G; growth arrest and DNA damage inducible gamma
       106486975 CDK1; cyclin dependent kinase 1
       106484407 G2/mitotic-specific cyclin-B1-like
       106497404 CCNB3; cyclin B3
       106495525 MRE11; MRE11 homolog, double strand break repair nuclease
       106487246 RAD50; RAD50 double strand break repair protein
       106496199 NBN; nibrin
       106493490 ATM; ATM serine/threonine kinase
       106492744 CHEK2; checkpoint kinase 2
       106495809 RAD9A; RAD9 checkpoint clamp component A
       106495659 RAD9B; RAD9 checkpoint clamp component B
       106499562 RAD1; RAD1 checkpoint DNA exonuclease
       106492867 HUS1; HUS1 checkpoint clamp component
       106485832 ATR; ATR serine/threonine kinase
       106499367 M-phase inducer phosphatase 1-like
       106493464 SQSTM1; sequestosome 1
       106483921 GATA4; GATA binding protein 4
       106489678 TRAF3IP2; TRAF3 interacting protein 2
       106491979 NFKB1; nuclear factor kappa B subunit 1
       106483538 IL6; interleukin 6
       106491802 interleukin-8-like
       106491800 platelet factor 4-like
       106491895 interleukin-8-like
       106485113 C-X-C motif chemokine 5-like
       106485114 C-X-C motif chemokine 5-like
       106492834 IGFBP3; insulin like growth factor binding protein 3
       106495796 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2
       106498175 ZFP36L1; ZFP36 ring finger protein like 1
       106488627 CACNA1D; calcium voltage-gated channel subunit alpha1 D
       106484376 TRPV4; transient receptor potential cation channel subfamily V member 4
       106496405 transient receptor potential cation channel subfamily M member 7-like
       106494368 CAPN1; calpain 1
       106485511 CAPN11; calpain 11
       106482724 CAPN2; calpain 2
       106485365 CALML4; calmodulin like 4
       106485452 CALM2; calmodulin 2
       106482920 CALM1; calmodulin 1
       106492052 PPP3CA; protein phosphatase 3 catalytic subunit alpha
       106499981 PPP3CC; protein phosphatase 3 catalytic subunit gamma
       106498910 PPP3CB; protein phosphatase 3 catalytic subunit beta
       106495909 PPP3R1; protein phosphatase 3 regulatory subunit B, alpha
       106500234 NFATC1; nuclear factor of activated T-cells 1
       106491750 NFATC2; nuclear factor of activated T-cells 2
       106483280 NFATC3; nuclear factor of activated T-cells 3
       106489801 ITPR1; inositol 1,4,5-trisphosphate receptor type 1
       106488657 inositol 1
       106496749 ITPR3; inositol 1,4,5-trisphosphate receptor type 3
       106487533 SLC25A5; solute carrier family 25 member 5
       106490690 SLC25A6; solute carrier family 25 member 6
       106483997 ADP/ATP translocase 1
       106491850 SLC25A31; solute carrier family 25 member 31
       106491879 PPID; peptidylprolyl isomerase D
       106487263 VDAC1; voltage dependent anion channel 1
       106498931 VDAC2; voltage dependent anion channel 2
       106487778 VDAC3; voltage dependent anion channel 3
       106498571 MCU; mitochondrial calcium uniporter
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K06618 RB1; retinoblastoma-associated protein
K04681 RBL1; retinoblastoma-like protein 1
K16332 RBL2; retinoblastoma-like protein 2
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04682 E2F4_5; transcription factor E2F4/5
K04682 E2F4_5; transcription factor E2F4/5
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K07201 FOXO1; forkhead box protein O1
K09408 FOXO3; forkhead box protein O3
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K07830 RRAS2; Ras-related protein R-Ras2
K07831 MRAS; Ras-related protein M-Ras
K02833 HRAS; GTPase HRas
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K07208 RHEB; Ras homolog enriched in brain
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K11411 SIRT1; NAD+-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K21769 MYBL2; myb-related protein B
K21773 LIN9; protein lin-9
K21775 LIN52; protein lin-52
K21776 LIN54; protein lin-54
K10752 RBBP4; histone-binding protein RBBP4
K09406 FOXM; forkhead box protein M
K04377 MYC; Myc proto-oncogene protein
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K08015 RASSF5; Ras association domain-containing protein 5
K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K02678 ETS1; C-ets-1
K04432 MAP2K3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21771 CCNB3; G2/mitotic-specific cyclin-B3
K10865 MRE11; double-strand break repair protein MRE11
K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
K10867 NBN; nibrin
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]
K10995 RAD9B; cell cycle checkpoint control protein RAD9B
K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
K10903 HUS1; HUS1 checkpoint protein
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
K14381 SQSTM1; sequestosome 1
K09183 GATA4; GATA-binding protein 4
K21124 TRAF3IP2; adaptor protein CIKS
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K05405 IL6; interleukin 6
K10030 IL8; interleukin 8
K10030 IL8; interleukin 8
K10030 IL8; interleukin 8
K10030 IL8; interleukin 8
K10030 IL8; interleukin 8
K10138 IGFBP3; insulin-like growth factor-binding protein 3
K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
K18753 ZFP36L; butyrate response factor
K04851 CACNA1D; voltage-dependent calcium channel L type alpha-1D
K04973 TRPV4; transient receptor potential cation channel subfamily V member 4
K04982 TRPM7; transient receptor potential cation channel subfamily M member 7 [EC:2.7.11.1]
K01367 CAPN1; calpain-1 [EC:3.4.22.52]
K01367 CAPN1; calpain-1 [EC:3.4.22.52]
K03853 CAPN2; calpain-2 [EC:3.4.22.53]
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3; nuclear factor of activated T-cells, cytoplasmic 3
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05864 PPID; peptidyl-prolyl isomerase D [EC:5.2.1.8]
K05862 VDAC1; voltage-dependent anion channel protein 1
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K20858 MCU; calcium uniporter protein, mitochondrial
 
   09144 Cellular community - eukaryotes
 
   09145 Cellular community - prokaryotes
 
   09142 Cell motility
 
 09150 Organismal Systems
 
 09160 Human Diseases
 
 09180 Brite Hierarchies
 
 09190 Not Included in Pathway or Brite

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: December 1, 2020