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KO |
Eukaryotic type
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Sister chromatid cohesion proteins
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Meiosis-specific proteins
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Nucleosome assembly factors
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Histone modification proteins
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HATs (histone acetyltransferases)
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HAT complexes
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HDACs (histone deacetylases)
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HDAC complexes
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HMTs (histone methyltransferases)
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HKMTs (histone lysine methyltransferases)
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106048498 ASH1L; histone-lysine N-methyltransferase ASH1L isoform X1
106045654 DOT1L; histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
106037080 EHMT1; histone-lysine N-methyltransferase EHMT1 isoform X6
106048025 EZH1; histone-lysine N-methyltransferase EZH1
106048735 EZH2; histone-lysine N-methyltransferase EZH2 isoform X2
106039772 KMT2A; LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2A
106047718 KMT2D; histone-lysine N-methyltransferase 2D
106046952 KMT2C; histone-lysine N-methyltransferase 2C isoform X1
106043274 KMT2E; inactive histone-lysine N-methyltransferase 2E isoform X1
106049510 NSD1; histone-lysine N-methyltransferase, H3 lysine-36 specific
106034357 NSD2; histone-lysine N-methyltransferase NSD2
106044410 NSD3; histone-lysine N-methyltransferase NSD3 isoform X1
106040219 PRDM2; PR domain zinc finger protein 2 isoform X1
106031974 MECOM; histone-lysine N-methyltransferase MECOM isoform X1
106046221 PRDM6; putative histone-lysine N-methyltransferase PRDM6
106047640 ZNF488; zinc finger protein 488
125184039 PRDM8; PR domain zinc finger protein 8
125181407 PRDM12; PR domain zinc finger protein 12
106044631 PRDM16; histone-lysine N-methyltransferase PRDM16 isoform X3
106031413 SETD1B; LOW QUALITY PROTEIN: histone-lysine N-methyltransferase SETD1B
106046805 SETD2; histone-lysine N-methyltransferase SETD2
106036142 SETD4; SET domain-containing protein 4 isoform X1
106033321 SETD6; N-lysine methyltransferase SETD6
106040965 SETD7; histone-lysine N-methyltransferase SETD7 isoform X1
106031170 KMT5A; N-lysine methyltransferase KMT5A isoform X1
106049268 SETDB1; LOW QUALITY PROTEIN: histone-lysine N-methyltransferase SETDB1
106035084 SETDB2; histone-lysine N-methyltransferase SETDB2 isoform X1
106036705 histone-lysine N-methyltransferase SETMAR
106033933 SMYD1; histone-lysine N-methyltransferase SMYD1
106049693 SMYD3; histone-lysine N-methyltransferase SMYD3
106031578 SMYD2; N-lysine methyltransferase SMYD2
106046190 SUV39H2; histone-lysine N-methyltransferase SUV39H2
106038840 KMT5B; histone-lysine N-methyltransferase KMT5B isoform X2
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K06101 ASH1L; [histone H3]-lysine4 N-trimethyltransferase ASH1L [EC:2.1.1.354]
K11427 DOT1L; [histone H3]-lysine79 N-trimethyltransferase [EC:2.1.1.360]
K11420 EHMT; [histone H3]-lysine9 N-trimethyltransferase EHMT [EC:2.1.1.355]
K17451 EZH1; [histone H3]-lysine27 N-trimethyltransferase EZH1 [EC:2.1.1.356]
K11430 EZH2; [histone H3]-lysine27 N-trimethyltransferase EZH2 [EC:2.1.1.356]
K09186 MLL1; [histone H3]-lysine4 N-trimethyltransferase MLL1 [EC:2.1.1.354]
K09187 MLL2; [histone H3]-lysine4 N-trimethyltransferase MLL2 [EC:2.1.1.354]
K09188 MLL3; [histone H3]-lysine4 N-trimethyltransferase MLL3 [EC:2.1.1.354]
K09189 MLL5; [histone H3]-lysine4 N-trimethyltransferase MLL5 [EC:2.1.1.354]
K15588 NSD1; [histone H3]-lysine36 N-dimethyltransferase NSD1 [EC:2.1.1.357]
K11424 WHSC1; [histone H3]-lysine36 N-dimethyltransferase NSD2 [EC:2.1.1.357]
K11425 WHSC1L1; [histone H3]-lysine4 N-dimethyltransferase / [histone H3]-lysine27 N-dimethyltransferase [EC:2.1.1.370 2.1.1.371]
K11432 PRDM2; [histone H3]-lysine9 N-trimethyltransferase PRDM2 [EC:2.1.1.355]
K04462 MECOM; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
K20795 PRDM6; [histone H4]-lysine20 N-methyltransferase PRDM6 [EC:2.1.1.361]
K20797 PRDM8; PR domain zinc finger protein 8 [EC:2.1.1.-]
K20797 PRDM8; PR domain zinc finger protein 8 [EC:2.1.1.-]
K24255 PRDM12; PR domain zinc finger protein 12 [EC:2.1.1.-]
K22410 PRDM16; [histone H3]-lysine9 N-methyltransferase [EC:2.1.1.367]
K11422 SETD1; [histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:2.1.1.354]
K11423 SETD2; [histone H3]-lysine36 N-trimethyltransferase [EC:2.1.1.359]
K27277 SETD4; SET domain-containing protein 4 [EC:2.1.1.- 2.1.1.364]
K05302 SETD6; N-lysine methyltransferase SETD6 [EC:2.1.1.-]
K11431 SETD7; [histone H3]-lysine4 N-methyltransferase [EC:2.1.1.364]
K11428 SETD8; [histone H4]-lysine20 N-methyltransferase SETD8 [EC:2.1.1.361]
K11421 SETDB1; [histone H3]-N6,N6-dimethyl-lysine9 N-methyltransferase [EC:2.1.1.366]
K18494 SETDB2; [histone H3]-lysine9 N-trimethyltransferase SETDB2 [EC:2.1.1.355]
K11433 SETMAR; [histone H3]-lysine36 N-dimethyltransferase SETMAR [EC:2.1.1.357]
K11426 SMYD; [histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:2.1.1.354 2.1.1.357]
K11426 SMYD; [histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:2.1.1.354 2.1.1.357]
K11426 SMYD; [histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:2.1.1.354 2.1.1.357]
K11419 SUV39H; [histone H3]-lysine9 N-trimethyltransferase SUV39H [EC:2.1.1.355]
K11429 SUV420H; [histone H4]-N-methyl-L-lysine20 N-methyltransferase [EC:2.1.1.362]
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PRMTs (protein arginine metyltransferases)
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HMT complexes
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Histone demethylases
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Polycomb repressive complex (PRC) and associated proteins
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Sir proteins
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Other histone modification proteins
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Chromosome condensation proteins
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Centromeric chromatin formation proteins
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Heterochromatin formation proteins
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Gene silencing
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Centrosome formation proteins
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Sister chromatid separation proteins
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Chromatin remodeling factors
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Prokaryotic type
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