KEGG Orthology (KO) - Alligator sinensis (Chinese alligator)

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     KO
 09100 Metabolism
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
   09131 Membrane transport
 
   09132 Signal transduction
     02020 Two-component system
     04010 MAPK signaling pathway [PATH:asn04010]
     04013 MAPK signaling pathway - fly
     04016 MAPK signaling pathway - plant
     04011 MAPK signaling pathway - yeast
     04012 ErbB signaling pathway [PATH:asn04012]
       102388605 EGF; pro-epidermal growth factor
       102379226 TGFA; protransforming growth factor alpha isoform X2
       102379659 AREG; amphiregulin
       102378285 EGFR; epidermal growth factor receptor isoform X1
       102369818 ERBB2; receptor tyrosine-protein kinase erbB-2 isoform X1
       102369875 PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1
       102368895 1-phosphatidylinositol 4
       102378303 PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform X1
       102372048 CAMK2A; calcium/calmodulin-dependent protein kinase type II subunit alpha
       102382581 CAMK2D; calcium/calmodulin-dependent protein kinase type II subunit delta isoform X2
       102369083 CAMK2B; calcium/calmodulin-dependent protein kinase type II subunit beta isoform X1
       102376749 CAMK2G; calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1
       102377784 PRKCA; protein kinase C alpha type isoform X1
       102368878 PRKCB; protein kinase C beta type
       102371860 PRKCG; protein kinase C gamma type
       102372644 CBL; E3 ubiquitin-protein ligase CBL isoform X1
       102384451 CBLB; E3 ubiquitin-protein ligase CBL-B isoform X1
       102380420 signal transducer and activator of transcription 5B isoform X1
       102371874 SRC; proto-oncogene tyrosine-protein kinase Src isoform X1
       102375664 PTK2; focal adhesion kinase 1 isoform X11
       102371723 CRKL; crk-like protein
       102377791 CRK; adapter molecule crk
       102368526 ABL1; tyrosine-protein kinase ABL1 isoform X1
       102368728 ABL2; tyrosine-protein kinase ABL2
       102370411 NCK2; cytoplasmic protein NCK2 isoform X1
       102367767 PAK1; serine/threonine-protein kinase PAK 1 isoform X1
       102385322 PAK2; serine/threonine-protein kinase PAK 2 isoform X1
       102383228 PAK3; LOW QUALITY PROTEIN: serine/threonine-protein kinase PAK 3
       102373773 PAK4; serine/threonine-protein kinase PAK 4
       102376998 PAK5; serine/threonine-protein kinase PAK 5 isoform X1
       102376676 PAK6; serine/threonine-protein kinase PAK 6
       102379245 MAP2K4; dual specificity mitogen-activated protein kinase kinase 4
       102372350 MAP2K7; dual specificity mitogen-activated protein kinase kinase 7 isoform X1
       102376154 MAPK8; mitogen-activated protein kinase 8 isoform X1
       102374542 mitogen-activated protein kinase 10 isoform X6
       102376040 MAPK9; mitogen-activated protein kinase 9 isoform X2
       102374896 JUN; transcription factor AP-1
       112547857 ELK1; ETS domain-containing protein Elk-1 isoform X1
       102379412 BTC; probetacellulin
       102372604 HBEGF; proheparin-binding EGF-like growth factor
       102379901 EREG; proepiregulin
       102376821 ERBB3; receptor tyrosine-protein kinase erbB-3
       102382924 NRG1; pro-neuregulin-1, membrane-bound isoform isoform X1
       102372853 NRG2; pro-neuregulin-2, membrane-bound isoform
       102387680 ERBB4; receptor tyrosine-protein kinase erbB-4
       102376721 SHC1; SHC-transforming protein 1 isoform X2
       102383911 SHC2; SHC-transforming protein 2 isoform X1
       102374227 SHC3; SHC-transforming protein 3
       102383468 SHC4; SHC-transforming protein 4 isoform X1
       102376596 GRB2; growth factor receptor-bound protein 2 isoform X1
       102382733 SOS1; son of sevenless homolog 1 isoform X1
       102387180 SOS2; LOW QUALITY PROTEIN: son of sevenless homolog 2
       102380807 HRAS; GTPase HRas
       112547860 GTPase HRas-like
       102373235 KRAS; GTPase KRas
       102382019 NRAS; GTPase NRas
       102380007 BRAF; serine/threonine-protein kinase B-raf
       102374398 RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1
       102373880 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1
       102375508 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2
       102376690 MAPK1; mitogen-activated protein kinase 1
       102375250 glycogen synthase kinase-3 alpha-like
       102370393 MYC; myc proto-oncogene protein
       102379491 GAB1; GRB2-associated-binding protein 1 isoform X1
       102376874 NRG3; pro-neuregulin-3, membrane-bound isoform
       102386434 NRG4; pro-neuregulin-4, membrane-bound isoform isoform X2
       102388304 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
       102372482 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1
       102387818 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
       102382060 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1
       102377899 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta isoform X1
       102380057 phosphatidylinositol 3-kinase regulatory subunit gamma
       102388514 AKT3; RAC-gamma serine/threonine-protein kinase isoform X2
       102388207 AKT2; RAC-beta serine/threonine-protein kinase
       102372104 AKT1; RAC-alpha serine/threonine-protein kinase isoform X1
       102372197 MTOR; serine/threonine-protein kinase mTOR isoform X2
       102387892 RPS6KB1; ribosomal protein S6 kinase beta-1 isoform X1
       102370189 RPS6KB2; ribosomal protein S6 kinase beta-2 isoform X1
       112548233 BAD; bcl2-associated agonist of cell death
       102387985 GSK3B; glycogen synthase kinase-3 beta isoform X3
       102368723 CDKN1B; cyclin-dependent kinase inhibitor 1B
       102379358 CDKN1A; cyclin-dependent kinase inhibitor 1
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K09782 AREG; amphiregulin
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K22517 CBLB; E3 ubiquitin-protein ligase CBL-B [EC:2.3.2.27]
K11224 STAT5B; signal transducer and activator of transcription 5B
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K08887 ABL2; abelson tyrosine-protein kinase 2 [EC:2.7.10.2]
K19862 NCK2; NCK adaptor protein 2
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3; p21-activated kinase 3 [EC:2.7.11.1]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K05736 PAK5; p21-activated kinase 5 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K04430 MAP2K4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04375 ELK1; ETS domain-containing protein Elk-1
K09783 BTC; betacellulin
K08523 HBEGF; heparin-binding EGF-like growth factor
K09784 EREG; epiregulin
K05084 ERBB3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
K05455 NRG1; neuregulin 1
K05456 NRG2; neuregulin 2
K05085 ERBB4; receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04377 MYC; Myc proto-oncogene protein
K09593 GAB1; GRB2-associated-binding protein 1
K05457 NRG3; neuregulin 3
K05458 NRG4; neuregulin 4
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
     04014 Ras signaling pathway
     04015 Rap1 signaling pathway
     04310 Wnt signaling pathway [PATH:asn04310]
     04330 Notch signaling pathway [PATH:asn04330]
     04340 Hedgehog signaling pathway [PATH:asn04340]
     04341 Hedgehog signaling pathway - fly
     04350 TGF-beta signaling pathway [PATH:asn04350]
     04390 Hippo signaling pathway
     04391 Hippo signaling pathway - fly
     04392 Hippo signaling pathway - multiple species
     04370 VEGF signaling pathway [PATH:asn04370]
     04371 Apelin signaling pathway [PATH:asn04371]
     04630 JAK-STAT signaling pathway
     04064 NF-kappa B signaling pathway
     04668 TNF signaling pathway
     04066 HIF-1 signaling pathway
     04068 FoxO signaling pathway [PATH:asn04068]
       102369002 TGFB1; transforming growth factor beta-1
       102382227 TGFB2; transforming growth factor beta-2
       102384560 TGFB3; transforming growth factor beta-3
       102370778 TGFBR1; TGF-beta receptor type-1
       102380434 TGFBR2; TGF-beta receptor type-2
       102371879 LOW QUALITY PROTEIN: TGF-beta receptor type-2-like
       102375399 SMAD4; mothers against decapentaplegic homolog 4 isoform X1
       102373921 mothers against decapentaplegic homolog 4-like
       102379863 SMAD3; mothers against decapentaplegic homolog 3 isoform X1
       102379013 STK11; serine/threonine-protein kinase STK11 isoform X1
       102374152 PRKAA2; 5'-AMP-activated protein kinase catalytic subunit alpha-2
       102375567 PRKAA1; 5'-AMP-activated protein kinase catalytic subunit alpha-1 isoform X1
       102382402 PRKAB1; 5'-AMP-activated protein kinase subunit beta-1
       102383969 PRKAB2; 5'-AMP-activated protein kinase subunit beta-2 isoform X1
       102383827 PRKAG1; 5'-AMP-activated protein kinase subunit gamma-1
       102381631 PRKAG2; 5'-AMP-activated protein kinase subunit gamma-2 isoform X1
       102377007 PRKAG3; 5'-AMP-activated protein kinase subunit gamma-3 isoform X2
       102376659 NLK; LOW QUALITY PROTEIN: serine/threonine-protein kinase NLK
       102367894 SKP2; S-phase kinase-associated protein 2
       102385768 MDM2; E3 ubiquitin-protein ligase Mdm2 isoform X1
       102374512 SETD7; histone-lysine N-methyltransferase SETD7
       102369497 CREBBP; CREB-binding protein
       102371912 EP300; histone acetyltransferase p300 isoform X1
       102369643 SIRT1; NAD-dependent protein deacetylase sirtuin-1 isoform X1
       102381850 USP7; ubiquitin carboxyl-terminal hydrolase 7 isoform X2
       102370597 SLC2A4; solute carrier family 2, facilitated glucose transporter member 4
       102376154 MAPK8; mitogen-activated protein kinase 8 isoform X1
       102374542 mitogen-activated protein kinase 10 isoform X6
       102376040 MAPK9; mitogen-activated protein kinase 9 isoform X2
       102385000 STK4; serine/threonine-protein kinase 4
       102372626 IGF1; insulin-like growth factor I
       102387852 IGF1R; insulin-like growth factor 1 receptor isoform X1
       102378642 INS; insulin
       102378715 INSR; insulin receptor isoform X1
       102372136 IRS1; insulin receptor substrate 1
       102382907 IRS4; insulin receptor substrate 4
       102374791 IRS2; insulin receptor substrate 2
       102388304 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
       102372482 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1
       102387818 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
       102382060 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1
       102377899 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta isoform X1
       102380057 phosphatidylinositol 3-kinase regulatory subunit gamma
       102383992 PDPK1; 3-phosphoinositide-dependent protein kinase 1 isoform X1
       102374729 CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha
       102377560 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta
       106721809 PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
       102388514 AKT3; RAC-gamma serine/threonine-protein kinase isoform X2
       102388207 AKT2; RAC-beta serine/threonine-protein kinase
       102372104 AKT1; RAC-alpha serine/threonine-protein kinase isoform X1
       102371183 SGK1; serine/threonine-protein kinase Sgk1
       102383702 SGK2; serine/threonine-protein kinase Sgk2 isoform X2
       102368712 serine/threonine-protein kinase Sgk3 isoform X1
       102388853 FOXO1; forkhead box protein O1
       102373584 FOXO3; forkhead box protein O3
       102380411 FOXO4; forkhead box protein O4 isoform X2
       102377293 FOXO6; forkhead box protein O6
       102378290 GRM1; metabotropic glutamate receptor 1
       102378768 HOMER1; homer protein homolog 1 isoform X2
       102386688 HOMER2; homer protein homolog 2 isoform X1
       102375148 HOMER3; homer protein homolog 3
       102375559 CSNK1E; casein kinase I isoform X1
       102377828 IL6; interleukin-6
       102383212 IL10; interleukin-10
       102381312 STAT3; signal transducer and activator of transcription 3 isoform X1
       102388605 EGF; pro-epidermal growth factor
       102378285 EGFR; epidermal growth factor receptor isoform X1
       102376596 GRB2; growth factor receptor-bound protein 2 isoform X1
       102382733 SOS1; son of sevenless homolog 1 isoform X1
       102387180 SOS2; LOW QUALITY PROTEIN: son of sevenless homolog 2
       102380807 HRAS; GTPase HRas
       112547860 GTPase HRas-like
       102373235 KRAS; GTPase KRas
       102382019 NRAS; GTPase NRas
       102380007 BRAF; serine/threonine-protein kinase B-raf
       102374398 RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1
       102373880 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1
       102375508 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2
       102376690 MAPK1; mitogen-activated protein kinase 1
       102375250 glycogen synthase kinase-3 alpha-like
       102374196 MAPK12; mitogen-activated protein kinase 12 isoform X1
       102375954 MAPK13; mitogen-activated protein kinase 13 isoform X1
       102376541 MAPK14; mitogen-activated protein kinase 14 isoform X1
       102375835 MAPK11; mitogen-activated protein kinase 11
       102376317 CDK2; cyclin-dependent kinase 2
       102368991 PRMT1; protein arginine N-methyltransferase 1 isoform X1
       102382896 FOXG1; forkhead box protein G1
       102381467 CCNB1; G2/mitotic-specific cyclin-B1 isoform X2
       102376865 CCNB2; G2/mitotic-specific cyclin-B2
       102373322 CCNB3; LOW QUALITY PROTEIN: G2/mitotic-specific cyclin-B3
       102378816 CCND1; G1/S-specific cyclin-D1
       102368440 CCNG2; cyclin-G2 isoform X2
       102368723 CDKN1B; cyclin-dependent kinase inhibitor 1B
       102379358 CDKN1A; cyclin-dependent kinase inhibitor 1
       102372889 RBL2; retinoblastoma-like protein 2 isoform X1
       102370156 PLK1; serine/threonine-protein kinase PLK1
       102380732 PLK2; serine/threonine-protein kinase PLK2
       102375098 PLK3; serine/threonine-protein kinase PLK3
       102387484 PLK4; serine/threonine-protein kinase PLK4
       102374205 GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta
       102372381 GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma
       102374172 GADD45A; growth arrest and DNA damage-inducible protein GADD45 alpha
       102381984 BCL2L11; bcl-2-like protein 11 isoform X2
       102371031 TNFSF10; tumor necrosis factor ligand superfamily member 10 isoform X1
       102378128 BCL6; B-cell lymphoma 6 protein isoform X1
       102379746 BNIP3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
       102375610 ATG12; ubiquitin-like protein ATG12
       102367983 GABARAPL2; gamma-aminobutyric acid receptor-associated protein-like 2
       102385155 GABARAP; gamma-aminobutyric acid receptor-associated protein
       102382529 GABARAPL1; gamma-aminobutyric acid receptor-associated protein-like 1
       102372846 CAT; catalase
       102380086 SOD2; superoxide dismutase [Mn], mitochondrial
       102387373 serine-protein kinase ATM isoform X1
       102377413 PCK1; phosphoenolpyruvate carboxykinase, cytosolic [GTP]
       102384985 PCK2; phosphoenolpyruvate carboxykinase [GTP], mitochondrial
       102381208 G6PC3; glucose-6-phosphatase 3
       102381465 glucose-6-phosphatase-like
       102381714 glucose-6-phosphatase
       102385680 G6PC2; glucose-6-phosphatase 2
       102368640 IL7R; interleukin-7 receptor subunit alpha
       102380575 KLF2; Krueppel-like factor 2
       102387729 S1PR1; sphingosine 1-phosphate receptor 1
       102386810 S1PR4; sphingosine 1-phosphate receptor 4
       102382683 RAG1; LOW QUALITY PROTEIN: V(D)J recombination-activating protein 1
       102367820 RAG2; V(D)J recombination-activating protein 2
       102372474 FBXO25; F-box only protein 25 isoform X1
       102383630 FBXO32; F-box only protein 32
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04501 SMAD4; mothers against decapentaplegic homolog 4
K23605 SMAD3; mothers against decapentaplegic homolog 3
K07298 STK11; serine/threonine-protein kinase 11 [EC:2.7.11.1]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K04468 NLK; nemo like kinase [EC:2.7.11.24]
K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K11431 SETD7; [histone H3]-lysine4 N-methyltransferase [EC:2.1.1.364]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K11411 SIRT1; NAD+-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
K07191 SLC2A4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04411 STK4; serine/threonine kinase 4
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04526 INS; insulin
K04527 INSR; insulin receptor [EC:2.7.10.1]
K16172 IRS1; insulin receptor substrate 1
K07187 IRS2; insulin receptor substrate 2
K07187 IRS2; insulin receptor substrate 2
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K13302 SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
K13303 SGK2; serum/glucocorticoid-regulated kinase 2 [EC:2.7.11.1]
K13304 SGK3; serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1]
K07201 FOXO1; forkhead box protein O1
K09408 FOXO3; forkhead box protein O3
K12358 FOXO4; forkhead box protein O4
K17847 FOXO6; forkhead box protein O6
K04603 GRM1; metabotropic glutamate receptor 1
K15010 HOMER; homer
K15010 HOMER; homer
K15010 HOMER; homer
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K05405 IL6; interleukin 6
K05443 IL10; interleukin 10
K04692 STAT3; signal transducer and activator of transcription 3
K04357 EGF; epidermal growth factor
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K11434 PRMT1; type I protein arginine methyltransferase [EC:2.1.1.319]
K09385 FOXG; forkhead box protein G
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K21771 CCNB3; G2/mitotic-specific cyclin-B3
K04503 CCND1; G1/S-specific cyclin-D1
K10146 CCNG2; cyclin G2
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K16332 RBL2; retinoblastoma-like protein 2
K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
K08861 PLK2; polo-like kinase 2 [EC:2.7.11.21]
K08862 PLK3; polo-like kinase 3 [EC:2.7.11.21]
K08863 PLK4; polo-like kinase 4 [EC:2.7.11.21]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K16341 BCL2L11; Bcl-2-like protein 11
K04721 TNFSF10; tumor necrosis factor ligand superfamily member 10
K15618 BCL6; B-cell lymphoma 6 protein
K15464 BNIP3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
K08336 ATG12; ubiquitin-like protein ATG12
K08341 GABARAP; GABA(A) receptor-associated protein
K08341 GABARAP; GABA(A) receptor-associated protein
K08341 GABARAP; GABA(A) receptor-associated protein
K03781 katE; catalase [EC:1.11.1.6]
K04564 SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K05072 IL7R; interleukin 7 receptor
K17845 KLF2; krueppel-like factor 2
K04288 S1PR1; sphingosine 1-phosphate receptor 1
K04293 S1PR4; sphingosine 1-phosphate receptor 4
K10628 RAG1; V(D)J recombination-activating protein 1 [EC:2.3.2.27]
K10988 RAG2; recombination-activating protein 2
K10305 FBXO25_32; F-box protein 25/32
K10305 FBXO25_32; F-box protein 25/32
     04020 Calcium signaling pathway [PATH:asn04020]
     04070 Phosphatidylinositol signaling system [PATH:asn04070]
     04072 Phospholipase D signaling pathway
     04071 Sphingolipid signaling pathway
     04024 cAMP signaling pathway
     04022 cGMP-PKG signaling pathway
     04151 PI3K-Akt signaling pathway
     04152 AMPK signaling pathway
     04150 mTOR signaling pathway [PATH:asn04150]
     04075 Plant hormone signal transduction
 
   09133 Signaling molecules and interaction
 
 09140 Cellular Processes
 
   09141 Transport and catabolism
 
   09143 Cell growth and death
     04110 Cell cycle [PATH:asn04110]
       102378816 CCND1; G1/S-specific cyclin-D1
       102386423 CCND3; G1/S-specific cyclin-D3 isoform X1
       102387479 CDK4; cyclin-dependent kinase 4
       102387975 CDK6; cyclin-dependent kinase 6 isoform X2
       102379703 RB1; retinoblastoma-associated protein isoform X1
       102379720 RBL1; retinoblastoma-like protein 1 isoform X1
       102372889 RBL2; retinoblastoma-like protein 2 isoform X1
       102368526 ABL1; tyrosine-protein kinase ABL1 isoform X1
       102378546 HDAC2; histone deacetylase 2
       102375203 HDAC1; histone deacetylase 1 isoform X1
       102379028 E2F1; transcription factor E2F1
       102375233 E2F2; transcription factor E2F2 isoform X1
       102387519 E2F3; transcription factor E2F3
       102378682 E2F5; transcription factor E2F5
       102381316 E2F4; transcription factor E2F4
       102373700 TFDP1; transcription factor Dp-1 isoform X1
       102377745 TFDP2; transcription factor Dp-2 isoform X1
       102387985 GSK3B; glycogen synthase kinase-3 beta isoform X3
       102369002 TGFB1; transforming growth factor beta-1
       102382227 TGFB2; transforming growth factor beta-2
       102384560 TGFB3; transforming growth factor beta-3
       102370509 SMAD2; mothers against decapentaplegic homolog 2 isoform X1
       102379863 SMAD3; mothers against decapentaplegic homolog 3 isoform X1
       102375399 SMAD4; mothers against decapentaplegic homolog 4 isoform X1
       102373921 mothers against decapentaplegic homolog 4-like
       102370393 MYC; myc proto-oncogene protein
       102369378 ZBTB17; LOW QUALITY PROTEIN: zinc finger and BTB domain-containing protein 17
       102370721 CDKN2C; cyclin-dependent kinase 4 inhibitor C
       102368723 CDKN1B; cyclin-dependent kinase inhibitor 1B
       102379358 CDKN1A; cyclin-dependent kinase inhibitor 1
       102368597 CCNE2; G1/S-specific cyclin-E2 isoform X1
       102382034 CCNE1; LOW QUALITY PROTEIN: G1/S-specific cyclin-E1
       102376317 CDK2; cyclin-dependent kinase 2
       102382934 SKP1; S-phase kinase-associated protein 1
       102371987 CUL1; cullin-1 isoform X2
       102372162 RBX1; E3 ubiquitin-protein ligase RBX1 isoform X1
       102367894 SKP2; S-phase kinase-associated protein 2
       102388230 CCNA2; cyclin-A2
       102377779 CCNA1; cyclin-A1 isoform X1
       102387844 CDC6; cell division control protein 6 homolog
       102369633 CDC45; cell division control protein 45 homolog
       102376025 CDC7; cell division cycle 7-related protein kinase
       102374530 DBF4; LOW QUALITY PROTEIN: protein DBF4 homolog A
       102385352 CDK1; LOW QUALITY PROTEIN: cyclin-dependent kinase 1
       102381467 CCNB1; G2/mitotic-specific cyclin-B1 isoform X2
       102376865 CCNB2; G2/mitotic-specific cyclin-B2
       102373322 CCNB3; LOW QUALITY PROTEIN: G2/mitotic-specific cyclin-B3
       102369674 CDC25B; M-phase inducer phosphatase 2 isoform X1
       102384314 CDC25C; M-phase inducer phosphatase 3 isoform X2
       102374123 YWHAB; 14-3-3 protein beta/alpha
       102381413 YWHAZ; 14-3-3 protein zeta/delta
       102383521 YWHAQ; 14-3-3 protein theta
       102377548 YWHAE; 14-3-3 protein epsilon
       102370460 YWHAH; 14-3-3 protein eta
       102382669 YWHAG; 14-3-3 protein gamma
       102370156 PLK1; serine/threonine-protein kinase PLK1
       102374380 WEE1; wee1-like protein kinase isoform X1
       102369847 WEE2; wee1-like protein kinase 2 isoform X1
       102372270 PKMYT1; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
       102382230 CCNH; cyclin-H
       102380983 CDK7; cyclin-dependent kinase 7 isoform X1
       102381729 ANAPC1; anaphase-promoting complex subunit 1
       102369659 ANAPC2; anaphase-promoting complex subunit 2 isoform X1
       102377005 CDC27; cell division cycle protein 27 homolog isoform X1
       102374314 ANAPC4; anaphase-promoting complex subunit 4
       102380220 ANAPC5; anaphase-promoting complex subunit 5 isoform X2
       102376565 CDC16; cell division cycle protein 16 homolog isoform X1
       102381938 ANAPC7; anaphase-promoting complex subunit 7 isoform X1
       102386626 CDC23; cell division cycle protein 23 homolog
       102372148 ANAPC10; anaphase-promoting complex subunit 10 isoform X1
       102382940 ANAPC11; anaphase-promoting complex subunit 11
       102377802 CDC26; anaphase-promoting complex subunit CDC26
       102377327 ANAPC13; anaphase-promoting complex subunit 13
       102378256 CDC20; cell division cycle protein 20 homolog
       102374474 PTTG1; securin
       102377591 ESPL1; separin
       102376137 SMC1B; structural maintenance of chromosomes protein 1B isoform X2
       102377044 SMC1A; structural maintenance of chromosomes protein 1A
       102376456 SMC3; structural maintenance of chromosomes protein 3
       102382279 cohesin subunit SA-2-like isoform X1
       102385924 STAG2; cohesin subunit SA-2
       102380453 STAG1; cohesin subunit SA-1 isoform X1
       102383826 RAD21; double-strand-break repair protein rad21 homolog
       102373412 RAD21L1; double-strand-break repair protein rad21-like protein 1
       102374178 TTK; dual specificity protein kinase TTK
       102383453 BUB1; mitotic checkpoint serine/threonine-protein kinase BUB1
       102386757 BUB3; mitotic checkpoint protein BUB3 isoform X1
       102376270 BUB1B; mitotic checkpoint serine/threonine-protein kinase BUB1 beta isoform X1
       102373658 mitotic spindle assembly checkpoint protein MAD1-like
       102382343 MAD1L1; mitotic spindle assembly checkpoint protein MAD1
       102386165 MAD2L1; mitotic spindle assembly checkpoint protein MAD2A
       102372859 MAD2L2; mitotic spindle assembly checkpoint protein MAD2B
       102377576 FZR1; fizzy-related protein homolog
       102386817 CDC14B; dual specificity protein phosphatase CDC14B isoform X3
       102373351 CDC14A; dual specificity protein phosphatase CDC14A isoform X1
       102377502 ATR; serine/threonine-protein kinase ATR isoform X1
       102387373 serine-protein kinase ATM isoform X1
       102376594 TP53; cellular tumor antigen p53 isoform X2
       102385348 CHEK1; serine/threonine-protein kinase Chk1
       102386466 CHEK2; serine/threonine-protein kinase Chk2
       102369497 CREBBP; CREB-binding protein
       102371912 EP300; histone acetyltransferase p300 isoform X1
       102387673 PRKDC; DNA-dependent protein kinase catalytic subunit
       102385768 MDM2; E3 ubiquitin-protein ligase Mdm2 isoform X1
       102374205 GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta
       102372381 GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma
       102374172 GADD45A; growth arrest and DNA damage-inducible protein GADD45 alpha
       102373511 PCNA; proliferating cell nuclear antigen
       102372214 SFN; 14-3-3 protein sigma
       102384816 CDC25A; LOW QUALITY PROTEIN: M-phase inducer phosphatase 1
       102380212 ORC1; origin recognition complex subunit 1
       102382138 ORC2; origin recognition complex subunit 2 isoform X2
       102372305 ORC3; origin recognition complex subunit 3 isoform X1
       102368471 ORC4; origin recognition complex subunit 4 isoform X1
       102373671 ORC5; origin recognition complex subunit 5 isoform X2
       102371164 ORC6; origin recognition complex subunit 6
       102381787 MCM2; DNA replication licensing factor MCM2
       102380361 MCM3; DNA replication licensing factor MCM3
       102385755 MCM4; DNA replication licensing factor MCM4 isoform X1
       102372977 MCM5; DNA replication licensing factor MCM5 isoform X1
       102370374 MCM6; DNA replication licensing factor MCM6
       102384122 MCM7; DNA replication licensing factor MCM7
K04503 CCND1; G1/S-specific cyclin-D1
K10152 CCND3; G1/S-specific cyclin-D3
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K04681 RBL1; retinoblastoma-like protein 1
K16332 RBL2; retinoblastoma-like protein 2
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04682 E2F4_5; transcription factor E2F4/5
K04682 E2F4_5; transcription factor E2F4/5
K04683 TFDP1; transcription factor Dp-1
K09392 TFDP2; transcription factor Dp-2
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04377 MYC; Myc proto-oncogene protein
K10500 ZBTB17; zinc finger and BTB domain-containing protein 17
K06622 CDKN2C; cyclin-dependent kinase inhibitor 2C
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K03094 SKP1; S-phase kinase-associated protein 1
K03347 CUL1; cullin 1
K03868 RBX1; RING-box protein 1 [EC:2.3.2.32]
K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K02213 CDC6; cell division control protein 6
K06628 CDC45; cell division control protein 45
K02214 CDC7; cell division control protein 7 [EC:2.7.11.1]
K06629 ASK; activator of S phase kinase
K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K21771 CCNB3; G2/mitotic-specific cyclin-B3
K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
K05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K06630 YWHAE; 14-3-3 protein epsilon
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
K06633 PKMYT; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase [EC:2.7.11.1]
K06634 CCNH; cyclin H
K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
K03348 APC1; anaphase-promoting complex subunit 1
K03349 APC2; anaphase-promoting complex subunit 2
K03350 APC3; anaphase-promoting complex subunit 3
K03351 APC4; anaphase-promoting complex subunit 4
K03352 APC5; anaphase-promoting complex subunit 5
K03353 APC6; anaphase-promoting complex subunit 6
K03354 APC7; anaphase-promoting complex subunit 7
K03355 APC8; anaphase-promoting complex subunit 8
K03357 APC10; anaphase-promoting complex subunit 10
K03358 APC11; anaphase-promoting complex subunit 11
K03359 APC12; anaphase-promoting complex subunit 12
K12456 APC13; anaphase-promoting complex subunit 13
K03363 CDC20; cell division cycle 20, cofactor of APC complex
K06635 PTTG; securin
K02365 ESP1; separase [EC:3.4.22.49]
K06636 SMC1; structural maintenance of chromosome 1
K06636 SMC1; structural maintenance of chromosome 1
K06669 SMC3; structural maintenance of chromosome 3 (chondroitin sulfate proteoglycan 6)
K06671 STAG1_2; cohesin complex subunit SA-1/2
K06671 STAG1_2; cohesin complex subunit SA-1/2
K06671 STAG1_2; cohesin complex subunit SA-1/2
K06670 SCC1; cohesin complex subunit SCC1
K06670 SCC1; cohesin complex subunit SCC1
K08866 TTK; serine/threonine-protein kinase TTK/MPS1 [EC:2.7.12.1]
K02178 BUB1; checkpoint serine/threonine-protein kinase [EC:2.7.11.1]
K02180 BUB3; cell cycle arrest protein BUB3
K06637 BUB1B; mitotic checkpoint serine/threonine-protein kinase BUB1 beta [EC:2.7.11.1]
K06679 MAD1; mitotic spindle assembly checkpoint protein MAD1
K06679 MAD1; mitotic spindle assembly checkpoint protein MAD1
K02537 MAD2; mitotic spindle assembly checkpoint protein MAD2
K13728 MAD2L2; mitotic spindle assembly checkpoint protein MAD2B
K03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
K06639 CDC14; cell division cycle 14 [EC:3.1.3.16 3.1.3.48]
K06639 CDC14; cell division cycle 14 [EC:3.1.3.16 3.1.3.48]
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K04451 TP53; tumor protein p53
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04802 PCNA; proliferating cell nuclear antigen
K06644 SFN; stratifin
K06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
K02603 ORC1; origin recognition complex subunit 1
K02604 ORC2; origin recognition complex subunit 2
K02605 ORC3; origin recognition complex subunit 3
K02606 ORC4; origin recognition complex subunit 4
K02607 ORC5; origin recognition complex subunit 5
K02608 ORC6; origin recognition complex subunit 6
K02540 MCM2; DNA replication licensing factor MCM2 [EC:3.6.4.12]
K02541 MCM3; DNA replication licensing factor MCM3 [EC:3.6.4.12]
K02212 MCM4; DNA replication licensing factor MCM4 [EC:3.6.4.12]
K02209 MCM5; DNA replication licensing factor MCM5 [EC:3.6.4.12]
K02542 MCM6; DNA replication licensing factor MCM6 [EC:3.6.4.12]
K02210 MCM7; DNA replication licensing factor MCM7 [EC:3.6.4.12]
     04111 Cell cycle - yeast
     04112 Cell cycle - Caulobacter
     04113 Meiosis - yeast
     04114 Oocyte meiosis [PATH:asn04114]
     04210 Apoptosis [PATH:asn04210]
     04214 Apoptosis - fly
     04215 Apoptosis - multiple species
     04216 Ferroptosis [PATH:asn04216]
     04217 Necroptosis [PATH:asn04217]
     04115 p53 signaling pathway [PATH:asn04115]
       102387373 serine-protein kinase ATM isoform X1
       102386466 CHEK2; serine/threonine-protein kinase Chk2
       102377502 ATR; serine/threonine-protein kinase ATR isoform X1
       102385348 CHEK1; serine/threonine-protein kinase Chk1
       102377312 GORAB; LOW QUALITY PROTEIN: RAB6-interacting golgin
       102385768 MDM2; E3 ubiquitin-protein ligase Mdm2 isoform X1
       102386667 MDM4; protein Mdm4 isoform X1
       102376594 TP53; cellular tumor antigen p53 isoform X2
       102368723 CDKN1B; cyclin-dependent kinase inhibitor 1B
       102379358 CDKN1A; cyclin-dependent kinase inhibitor 1
       102378816 CCND1; G1/S-specific cyclin-D1
       102386423 CCND3; G1/S-specific cyclin-D3 isoform X1
       102387479 CDK4; cyclin-dependent kinase 4
       102387975 CDK6; cyclin-dependent kinase 6 isoform X2
       102368597 CCNE2; G1/S-specific cyclin-E2 isoform X1
       102382034 CCNE1; LOW QUALITY PROTEIN: G1/S-specific cyclin-E1
       102376317 CDK2; cyclin-dependent kinase 2
       102372214 SFN; 14-3-3 protein sigma
       102381467 CCNB1; G2/mitotic-specific cyclin-B1 isoform X2
       102376865 CCNB2; G2/mitotic-specific cyclin-B2
       102385352 CDK1; LOW QUALITY PROTEIN: cyclin-dependent kinase 1
       102374205 GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta
       102372381 GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma
       102374172 GADD45A; growth arrest and DNA damage-inducible protein GADD45 alpha
       102371782 GTSE1; G2 and S phase-expressed protein 1
       102375471 FAS; tumor necrosis factor receptor superfamily member 6
       102383631 PIDD1; p53-induced death domain-containing protein 1
       102368783 tumor necrosis factor receptor superfamily member 6-like
       102378076 TNFRSF10B; tumor necrosis factor receptor superfamily member 10B
       102384848 caspase-8-like
       102385102 caspase-8-like
       102375926 BH3-interacting domain death agonist
       102384471 BAX; apoptosis regulator BAX isoform X1
       112549505 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
       106722985 SIVA1; apoptosis regulatory protein Siva
       102370658 BCL2L1; bcl-2-like protein 1
       102370035 BCL2; apoptosis regulator Bcl-2 isoform X1
       102387100 TP53I3; quinone oxidoreductase PIG3
       102383694 EI24; etoposide-induced protein 2.4 homolog
       102388450 protein shisa-5-like
       102375774 PERP; p53 apoptosis effector related to PMP-22
       106722558 p53 apoptosis effector related to PMP-22-like
       102388160 ZMAT3; zinc finger matrin-type protein 3 isoform X1
       102370192 SIAH1; E3 ubiquitin-protein ligase SIAH1 isoform X1
       102383053 cytochrome c
       102379965 cytochrome c
       102371819 APAF1; apoptotic protease-activating factor 1 isoform X1
       102384999 CASP9; caspase-9
       102383553 CASP3; caspase-3
       102369935 caspase-3-like
       102372808 AIFM2; apoptosis-inducing factor 2
       102372891 IGFBP3; insulin-like growth factor-binding protein 3
       102372626 IGF1; insulin-like growth factor I
       102369661 plasminogen activator inhibitor 1
       102385206 ADGRB1; LOW QUALITY PROTEIN: adhesion G protein-coupled receptor B1
       102378380 CD82; CD82 antigen
       102374383 THBS1; thrombospondin-1 isoform X2
       102369781 SERPINB5; serpin B5
       102374438 DDB2; DNA damage-binding protein 2 isoform X1
       102379850 RRM2B; ribonucleoside-diphosphate reductase subunit M2 B isoform X1
       102370540 RRM2; ribonucleoside-diphosphate reductase subunit M2
       102380167 sestrin-3-like isoform X1
       102381119 SESN3; sestrin-3
       102371151 SESN1; sestrin-1 isoform X2
       102368018 SESN2; sestrin-2 isoform X5
       106721809 PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
       102387523 TSC2; tuberin isoform X1
       102368009 STEAP3; metalloreductase STEAP3 isoform X1
       102383015 COP1; E3 ubiquitin-protein ligase COP1
       102379175 RCHY1; RING finger and CHY zinc finger domain-containing protein 1
       102386630 CCNG1; cyclin-G1
       102368440 CCNG2; cyclin-G2 isoform X2
       102368484 PPM1D; protein phosphatase 1D isoform X1
       102384735 TP73; tumor protein p73 isoform X1
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K19748 GORAB; RAB6-interacting golgin
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K10127 MDM4; protein Mdm4
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04503 CCND1; G1/S-specific cyclin-D1
K10152 CCND3; G1/S-specific cyclin-D3
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06644 SFN; stratifin
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K10129 GTSE1; G-2 and S-phase expressed protein 1
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K10130 LRDD; leucine-rich repeats and death domain-containing protein
K04722 TNFRSF10A_B; tumor necrosis factor receptor superfamily member 10A/B
K04722 TNFRSF10A_B; tumor necrosis factor receptor superfamily member 10A/B
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K10131 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
K22744 SIVA1; apoptosis regulatory protein Siva
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator Bcl-2
K10133 TP53I3; tumor protein p53-inducible protein 3 [EC:1.-.-.-]
K10134 EI24; etoposide-induced 2.4 mRNA
K10135 SCOTIN; scotin
K10136 PERP; TP53 apoptosis effector
K10136 PERP; TP53 apoptosis effector
K10137 ZMAT3; zinc finger, matrin type 3
K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K22745 AIFM2; apoptosis-inducing factor 2
K10138 IGFBP3; insulin-like growth factor-binding protein 3
K05459 IGF1; insulin-like growth factor 1
K03982 SERPINE1; plasminogen activator inhibitor 1
K04596 ADGRB1; adhesion G protein-coupled receptor B1
K06509 KAI1; CD82 antigen
K16857 THBS1; thrombospondin 1
K10139 SERPINB5; serpin B5
K10140 DDB2; DNA damage-binding protein 2
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K10141 SESN1_3; sestrin 1/3
K10141 SESN1_3; sestrin 1/3
K10141 SESN1_3; sestrin 1/3
K20394 SESN2; sestrin 2
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K07207 TSC2; tuberous sclerosis 2
K10142 STEAP3; metalloreductase STEAP3 [EC:1.16.1.-]
K10143 RFWD2; E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]
K10144 RCHY1; RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]
K10145 CCNG1; cyclin G1
K10146 CCNG2; cyclin G2
K10147 PPM1D; protein phosphatase 1D [EC:3.1.3.16]
K10148 TP73; tumor protein p73
     04218 Cellular senescence [PATH:asn04218]
       102369002 TGFB1; transforming growth factor beta-1
       102382227 TGFB2; transforming growth factor beta-2
       102384560 TGFB3; transforming growth factor beta-3
       102370778 TGFBR1; TGF-beta receptor type-1
       102380434 TGFBR2; TGF-beta receptor type-2
       102371879 LOW QUALITY PROTEIN: TGF-beta receptor type-2-like
       102370509 SMAD2; mothers against decapentaplegic homolog 2 isoform X1
       102379863 SMAD3; mothers against decapentaplegic homolog 3 isoform X1
       102387479 CDK4; cyclin-dependent kinase 4
       102387975 CDK6; cyclin-dependent kinase 6 isoform X2
       102378816 CCND1; G1/S-specific cyclin-D1
       102386423 CCND3; G1/S-specific cyclin-D3 isoform X1
       102379703 RB1; retinoblastoma-associated protein isoform X1
       102379720 RBL1; retinoblastoma-like protein 1 isoform X1
       102372889 RBL2; retinoblastoma-like protein 2 isoform X1
       102379028 E2F1; transcription factor E2F1
       102375233 E2F2; transcription factor E2F2 isoform X1
       102387519 E2F3; transcription factor E2F3
       102378682 E2F5; transcription factor E2F5
       102381316 E2F4; transcription factor E2F4
       102388304 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
       102372482 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1
       102387818 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
       102382060 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1
       102377899 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta isoform X1
       102380057 phosphatidylinositol 3-kinase regulatory subunit gamma
       102388853 FOXO1; forkhead box protein O1
       102373584 FOXO3; forkhead box protein O3
       102368723 CDKN1B; cyclin-dependent kinase inhibitor 1B
       102379358 CDKN1A; cyclin-dependent kinase inhibitor 1
       102376317 CDK2; cyclin-dependent kinase 2
       102368597 CCNE2; G1/S-specific cyclin-E2 isoform X1
       102382034 CCNE1; LOW QUALITY PROTEIN: G1/S-specific cyclin-E1
       102367803 major histocompatibility complex class I-related gene protein-like
       102378986 major histocompatibility complex class I-related gene protein-like
       102380209 class I histocompatibility antigen
       102383415 HLA class II histocompatibility antigen
       102379493 H-2 class I histocompatibility antigen
       102368919 major histocompatibility complex class I-related gene protein-like
       102384475 class I histocompatibility antigen
       102382365 major histocompatibility complex class I-related gene protein-like
       102385058 major histocompatibility complex class I-related gene protein-like
       102387244 DLA class I histocompatibility antigen
       102382206 major histocompatibility complex class I-related gene protein-like
       102375088 major histocompatibility complex class I-related gene protein-like isoform X1
       102386566 major histocompatibility complex class I-related gene protein-like
       102368503 major histocompatibility complex class I-related gene protein-like
       102378561 class I histocompatibility antigen
       102379232 major histocompatibility complex class I-related gene protein-like isoform X1
       102388210 major histocompatibility complex class I-related gene protein-like
       102388710 major histocompatibility complex class I-related gene protein-like
       112547860 GTPase HRas-like
       102373235 KRAS; GTPase KRas
       102382019 NRAS; GTPase NRas
       102371276 RRAS2; ras-related protein R-Ras2 isoform X1
       102381265 RRAS; ras-related protein R-Ras isoform X2
       102376534 MRAS; ras-related protein M-Ras isoform X1
       102380807 HRAS; GTPase HRas
       102388514 AKT3; RAC-gamma serine/threonine-protein kinase isoform X2
       102388207 AKT2; RAC-beta serine/threonine-protein kinase
       102372104 AKT1; RAC-alpha serine/threonine-protein kinase isoform X1
       102383470 TSC1; LOW QUALITY PROTEIN: hamartin
       102387523 TSC2; tuberin isoform X1
       102381385 RHEB; GTP-binding protein Rheb isoform X1
       102372197 MTOR; serine/threonine-protein kinase mTOR isoform X2
       106721809 PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
       102369643 SIRT1; NAD-dependent protein deacetylase sirtuin-1 isoform X1
       102388230 CCNA2; cyclin-A2
       102377779 CCNA1; cyclin-A1 isoform X1
       102368128 MYBL2; myb-related protein B isoform X1
       102387566 LIN9; protein lin-9 homolog isoform X2
       102379872 LIN37; protein lin-37 homolog
       102385082 LIN54; protein lin-54 homolog isoform X2
       102369710 RBBP4; histone-binding protein RBBP4 isoform X2
       102387724 FOXM1; forkhead box protein M1 isoform X1
       102370393 MYC; myc proto-oncogene protein
       102385768 MDM2; E3 ubiquitin-protein ligase Mdm2 isoform X1
       102376594 TP53; cellular tumor antigen p53 isoform X2
       102383946 RASSF5; LOW QUALITY PROTEIN: ras association domain-containing protein 5
       102370841 FBXW11; F-box/WD repeat-containing protein 11 isoform X1
       102381867 F-box/WD repeat-containing protein 1A
       102376526 HIPK2; homeodomain-interacting protein kinase 2 isoform X3
       102382671 HIPK3; homeodomain-interacting protein kinase 3 isoform X2
       102383402 HIPK1; LOW QUALITY PROTEIN: homeodomain-interacting protein kinase 1
       102375415 PPP1CC; serine/threonine-protein phosphatase PP1-gamma catalytic subunit
       102373171 PPP1CA; serine/threonine-protein phosphatase PP1-alpha catalytic subunit
       102383008 PPP1CB; serine/threonine-protein phosphatase PP1-beta catalytic subunit isoform X1
       102374398 RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1
       102373880 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1
       102375508 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2
       102376690 MAPK1; mitogen-activated protein kinase 1
       102375250 glycogen synthase kinase-3 alpha-like
       102381885 ETS1; protein C-ets-1 isoform X1
       102383945 MAP2K3; dual specificity mitogen-activated protein kinase kinase 3 isoform X1
       102373782 MAP2K6; dual specificity mitogen-activated protein kinase kinase 6 isoform X1
       102374196 MAPK12; mitogen-activated protein kinase 12 isoform X1
       102375954 MAPK13; mitogen-activated protein kinase 13 isoform X1
       102376541 MAPK14; mitogen-activated protein kinase 14 isoform X1
       102375835 MAPK11; mitogen-activated protein kinase 11
       102374205 GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta
       102372381 GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma
       102374172 GADD45A; growth arrest and DNA damage-inducible protein GADD45 alpha
       102385352 CDK1; LOW QUALITY PROTEIN: cyclin-dependent kinase 1
       102381467 CCNB1; G2/mitotic-specific cyclin-B1 isoform X2
       102376865 CCNB2; G2/mitotic-specific cyclin-B2
       102373322 CCNB3; LOW QUALITY PROTEIN: G2/mitotic-specific cyclin-B3
       102388581 MRE11; double-strand break repair protein MRE11
       102372882 RAD50; DNA repair protein RAD50 isoform X1
       102380627 NBN; nibrin isoform X1
       102387373 serine-protein kinase ATM isoform X1
       102386466 CHEK2; serine/threonine-protein kinase Chk2
       102369329 RAD9A; cell cycle checkpoint control protein RAD9A isoform X1
       102376415 RAD9B; cell cycle checkpoint control protein RAD9B
       102376989 RAD1; cell cycle checkpoint protein RAD1 isoform X1
       102386730 checkpoint protein HUS1-like
       102378578 HUS1; LOW QUALITY PROTEIN: checkpoint protein HUS1
       102377502 ATR; serine/threonine-protein kinase ATR isoform X1
       102385348 CHEK1; serine/threonine-protein kinase Chk1
       102384816 CDC25A; LOW QUALITY PROTEIN: M-phase inducer phosphatase 1
       102373404 SQSTM1; sequestosome-1 isoform X2
       102371754 GATA4; transcription factor GATA-4 isoform X1
       102384842 TRAF3IP2; adapter protein CIKS isoform X1
       102369946 NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1
       102377458 RELA; transcription factor p65
       102377828 IL6; interleukin-6
       102374630 interleukin-8-like
       102374877 interleukin-8-like
       102375355 interleukin-8-like
       102375115 interleukin-8-like
       102372891 IGFBP3; insulin-like growth factor-binding protein 3
       102369661 plasminogen activator inhibitor 1
       102383452 MAPKAPK2; MAP kinase-activated protein kinase 2
       102382484 ZFP36L1; mRNA decay activator protein ZFP36L1 isoform X1
       102373960 CACNA1D; voltage-dependent L-type calcium channel subunit alpha-1D
       102383407 TRPV4; LOW QUALITY PROTEIN: transient receptor potential cation channel subfamily V member 4
       102372173 TRPM7; transient receptor potential cation channel subfamily M member 7
       102368421 CAPN11; calpain-11
       102375021 CAPN1; calpain-1 catalytic subunit
       102373508 CAPN2; calpain-2 catalytic subunit
       102369688 calmodulin-alpha-like
       102374592 CALM3; calmodulin-3
       102369607 CALML6; calmodulin-like protein 6 isoform X1
       102373272 CALM2; calmodulin-2
       102381160 CALM1; calmodulin-1
       102381186 CALML4; calmodulin-like protein 4 isoform X1
       102386011 PPP3CA; serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X1
       102377124 PPP3CC; serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform isoform X1
       102382032 PPP3CB; serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X1
       102377091 PPP3R1; calcineurin subunit B type 1
       102386486 NFATC1; nuclear factor of activated T-cells, cytoplasmic 1
       102375111 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2 isoform X1
       102375265 NFATC3; nuclear factor of activated T-cells, cytoplasmic 3
       102385401 NFATC4; nuclear factor of activated T-cells, cytoplasmic 4 isoform X1
       102379206 ITPR1; inositol 1,4,5-trisphosphate receptor type 1 isoform X2
       102379727 inositol 1
       102381395 ITPR3; LOW QUALITY PROTEIN: inositol 1,4,5-trisphosphate receptor type 3
       102371094 SLC25A4; ADP/ATP translocase 1
       102384953 ADP/ATP translocase 3
       102376128 SLC25A5; ADP/ATP translocase 2
       102387986 SLC25A31; ADP/ATP translocase 4
       102380636 PPID; peptidyl-prolyl cis-trans isomerase D isoform X1
       102383593 VDAC1; voltage-dependent anion-selective channel protein 1 isoform X1
       102381104 VDAC2; voltage-dependent anion-selective channel protein 2 isoform X1
       102370144 VDAC3; voltage-dependent anion-selective channel protein 3
       102378241 MCU; calcium uniporter protein, mitochondrial
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K04503 CCND1; G1/S-specific cyclin-D1
K10152 CCND3; G1/S-specific cyclin-D3
K06618 RB1; retinoblastoma-associated protein
K04681 RBL1; retinoblastoma-like protein 1
K16332 RBL2; retinoblastoma-like protein 2
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04682 E2F4_5; transcription factor E2F4/5
K04682 E2F4_5; transcription factor E2F4/5
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K07201 FOXO1; forkhead box protein O1
K09408 FOXO3; forkhead box protein O3
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K07827 KRAS; GTPase KRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K07830 RRAS2; Ras-related protein R-Ras2
K07830 RRAS2; Ras-related protein R-Ras2
K07831 MRAS; Ras-related protein M-Ras
K02833 HRAS; GTPase HRas
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K07208 RHEB; Ras homolog enriched in brain
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K11411 SIRT1; NAD+-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K21769 MYBL2; myb-related protein B
K21773 LIN9; protein lin-9
K21774 LIN37; protein lin-37
K21776 LIN54; protein lin-54
K10752 RBBP4; histone-binding protein RBBP4
K09406 FOXM; forkhead box protein M
K04377 MYC; Myc proto-oncogene protein
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53; tumor protein p53
K08015 RASSF5; Ras association domain-containing protein 5
K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K02678 ETS1; C-ets-1
K04432 MAP2K3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K21771 CCNB3; G2/mitotic-specific cyclin-B3
K10865 MRE11; double-strand break repair protein MRE11
K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
K10867 NBN; nibrin
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]
K10995 RAD9B; cell cycle checkpoint control protein RAD9B
K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
K10903 HUS1; HUS1 checkpoint protein
K10903 HUS1; HUS1 checkpoint protein
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
K14381 SQSTM1; sequestosome 1
K09183 GATA4; GATA-binding protein 4
K21124 TRAF3IP2; adaptor protein CIKS
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K05405 IL6; interleukin 6
K10030 IL8; interleukin 8
K10030 IL8; interleukin 8
K10030 IL8; interleukin 8
K10030 IL8; interleukin 8
K10138 IGFBP3; insulin-like growth factor-binding protein 3
K03982 SERPINE1; plasminogen activator inhibitor 1
K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
K18753 ZFP36L; butyrate response factor
K04851 CACNA1D; voltage-dependent calcium channel L type alpha-1D
K04973 TRPV4; transient receptor potential cation channel subfamily V member 4
K04982 TRPM7; transient receptor potential cation channel subfamily M member 7 [EC:2.7.11.1]
K01367 CAPN1; calpain-1 [EC:3.4.22.52]
K01367 CAPN1; calpain-1 [EC:3.4.22.52]
K03853 CAPN2; calpain-2 [EC:3.4.22.53]
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4; nuclear factor of activated T-cells, cytoplasmic 4
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05864 PPID; peptidyl-prolyl isomerase D [EC:5.2.1.8]
K05862 VDAC1; voltage-dependent anion channel protein 1
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K20858 MCU; calcium uniporter protein, mitochondrial
 
   09144 Cellular community - eukaryotes
 
   09145 Cellular community - prokaryotes
 
   09142 Cell motility
 
 09150 Organismal Systems
 
 09160 Human Diseases
 
 09180 Brite Hierarchies
 
 09190 Not Included in Pathway or Brite

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: November 25, 2020