Target-based Classification of Drugs

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     Type
 G Protein-coupled receptors
 
 Ion channels
 
 Nuclear receptors
 
 Protein kinases
 
 Cytokines and receptors
 
 Cell surface molecules and ligands
 
 Transporters
 
 Enzymes
   Oxidoreductases (EC1)
     Dehydrogenases [EC:1.1.1.-]
     Dehydrogenases [EC:1.2.1.-]
     Dehydrogenases [EC:1.3.-.-]
     Amine oxidases [EC:1.4.3.-]
     Dihydrofolate reductase [EC:1.5.1.3]
     NAD(P)H dehydrogenase [EC:1.6.5.2]
     Peroxidase [EC:1.11.1.-]
     Peroxygenase [EC:1.11.2.-]
     Dioxygenases [EC:1.13.11.-]
     Prolyl 4-hydroxylase [EC:1.14.11.2]
     HIF hydroxylase [EC:1.14.11.29]
     Nitic oxide synthase [EC:1.14.13.39]
     Cytochrome P450 [EC:1.14.14.-]
     Other monooxygenases [EC:1.14.16.- 1.14.17.- 1.14.18.-]
     Prostaglandin synthase [EC:1.14.99.1]
       PTGS1 (COX1) [HSA:5742] [KO:K00509]
       PTGS2 (COX2) [HSA:5743] [KO:K11987]
         D07516  Benzydamine (INN)
         D01410  Benzydamine hydrochloride (JAN/USAN)
         D07517  Benzydamine salicylate
         D00109  Aspirin (JP17/USP) <JP>
         D05181  Aspirin aluminum (JP17)
         D07579  Aspirin calcium salt
         D07580  Aspirin DL-lysine (JAN)
         D07581  Aspirin magnesium salt
         D07582  Aspirin sodium
         D07141  Indobufen (INN)
         D07421  Aloxiprin (INN)
         D00141  Indomethacin (USP) <JP/US>
         D01565  Indometacin farnesil (JAN) <JP>
         D02110  Indomethacin sodium (USP) <JP/US>
         D00126  Ibuprofen (JP17/USP/INN) <JP/US>
         D01122  Ibuprofen piconol (JP17/USAN) <JP>
         D04490  Ibuprofen aluminum (USAN)
         D06606  Ibuprofen lysine (USAN) <JP/US>
         D08058  Ibuprofen arginine salt
         D08059  Ibuprofen sodium
         D09760  Ibuprofen sodium (USAN)
         D08501  Trolamine salicylate (USP)
         D07816  Diclofenac (USAN/INN) <US>
         D00903  Diclofenac potassium (USP) <US>
         D00904  Diclofenac sodium (JP17/USP) <JP/US>
         D07817  Diclofenac diethylamine
         D07818  Diclofenac hydroxyethylpyrrolidine <US>
         D07819  Diclofenac calcium
         D00118  Naproxen (JP17/USP/INN) <JP/US>
         D00970  Naproxen sodium (USP) <US>
         D10017  Naproxen etemesil (USAN)
         D00567  Celecoxib (JAN/USP/INN) <JP/US>
         D00510  Phenylbutazone (JP17/USP/INN)
         D08363  Phenylbutazone calcium
         D08364  Phenylbutazone sodium
         D08324  Oxyphenbutazone (INN)
         D05319  Oxyphenbutazone hydrate
         D00120  Sulindac (JP17/USP/INN) <JP/US>
         D02355  Tolmetin (USAN/INN)
         D00158  Tolmetin sodium (JAN/USP) <US>
         D01252  Alclofenac (JAN/USP/INN)
         D00315  Etodolac (JP17/USP/INN) <JP/US>
         D01582  Acemetacin (JP17/INN) <JP>
         D08427  Proglumetacin (INN)
         D01765  Proglumetacin maleate (JAN) <JP>
         D08104  Ketorolac (INN)
         D00813  Ketorolac tromethamine (USP) <US>
         D01545  Aceclofenac (JAN/INN)
         D01271  Bufexamac (JAN/INN)
         D00127  Piroxicam (JP17/USP/INN) <JP/US>
         D05511  Piroxicam betadex (USAN)
         D05512  Piroxicam cinnamate (USAN)
         D05513  Piroxicam olamine (USAN)
         D01767  Tenoxicam (JAN/USAN/INN)
         D07267  Droxicam (INN)
         D01866  Lornoxicam (JAN/USAN/INN) <JP>
         D00969  Meloxicam (JAN/USP/INN) <JP/US>
         D00132  Ketoprofen (JP17/USP/INN) <JP/US>
         D08102  Ketoprofen lysine
         D08103  Ketoprofen sodium
         D02350  Fenoprofen (USAN/INN)
         D00968  Fenoprofen calcium (JAN/USP) <US>
         D01344  Fenbufen (JP17/USAN/INN)
         D00330  Flurbiprofen (JP17/USP/INN) <JP/US>
         D01475  Flurbiprofen axetil (JAN) <JP>
         D02290  Flurbiprofen sodium (USP) <US>
         D10254  Esflurbiprofen (JAN)
         D01325  Tiaprofenic acid (JAN/INN) <JP>
         D00463  Oxaprozin (JP17/USP/INN) <JP/US>
         D07268  Ibuproxam (INN)
         D03715  Dexibuprofen (USAN/INN)
         D03718  Dexibuprofen lysine (USAN)
         D01513  Alminoprofen (JP17/INN)
         D07269  Dexketoprofen (INN)
         D09568  Naproxcinod (USAN/INN)
         D00151  Mefenamic acid (JP17/USP/INN) <JP/US>
         D01183  Tolfenamic acid (JAN/INN)
         D01581  Flufenamic acid (JAN/USAN/INN)
         D01823  Ufenamate (JAN/INN) <JP>
         D03254  Flufenamate aluminum (JAN) <JP>
         D02341  Meclofenamic acid (USAN/INN)
         D00169  Meclofenamate sodium (USP) <US>
         D08162  Meclofenamate sodium
         D00568  Rofecoxib (JAN/USAN/INN)
         D02709  Valdecoxib (USAN/INN)
         D03716  Parecoxib (USAN/INN)
         D03717  Parecoxib sodium (USAN)
         D03710  Etoricoxib (USAN/INN)
         D03714  Lumiracoxib (USAN/INN)
         D10656  Polmacoxib (USAN/INN)
         D00425  Nabumetone (JP17/USP/INN) <JP/US>
         D08275  Niflumic acid (INN)
         D01049  Nimesulide (JAN/INN)
         D06072  Tenidap (USAN/INN)
         D06073  Tenidap sodium (USAN)
         D04102  Etofenamate (USAN/INN)
         D01675  Felbinac (JP17/USAN/INN) <JP>
         D01841  Felbinac ethyl (JAN)
         D08374  Piketoprofen (INN)
         D08375  Piketoprofen hydrochloride
         D00810  Choline salicylate (JAN/USAN/INN)
         D00566  Sodium salicylate (JP17/USP) <JP>
         D01811  Salicylamide (JAN/USP/INN)
         D00428  Salsalate (USP/INN)
         D00130  Diflunisal (JAN/USP/INN) <US>
         D00217  Acetaminophen (JP17/USP) <JP/US>
         D07294  Propacetamol (INN)
         D08434  Propacetamol hydrochloride
         D01578  Pranoprofen (JP17/INN) <JP>
         D05143  Nepafenac (JAN/USAN/INN) <JP/US>
         D07541  Bromfenac (INN)
         D03163  Bromfenac sodium (USAN) <JP/US>
         D00827  Magnesium salicylate (USP)
         D01090  Pamicogrel (JAN/INN)
         D01397  Ampiroxicam (JP17/INN) <JP>
         D01547  Zaltoprofen (JP17/INN) <JP>
         D01557  Glycol salicylate (JAN)
         D01709  Loxoprofen sodium hydrate (JP17) <JP>
         D01788  Amfenac sodium (USAN)
         D01974  Tilmacoxib (JAN/USAN/INN)
         D03410  Carprofen (USP/INN)
         D03652  Darbufelone mesylate (USAN)
         D03689  Deracoxib (USAN)
         D03712  Firocoxib (USAN/INN)
         D04863  Mavacoxib (USAN)
         D05275  Orpanoxin (USAN/INN)
         D05451  Phenbutazone sodium glycerate (USAN)
         D05598  Pravadoline maleate (USAN)
         D05791  Salicylate meglumine (USAN)
         D06017  Tebufelone (USAN/INN)
         D06364  Zidometacin (USAN/INN)
         D07443  Amfenac (INN)
         D07453  Amtolmetin guacil (INN)
         D07888  Eltenac (INN)
         D08149  Loxoprofen (INN)
         D08657  Apricoxib (USAN/INN)
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
     Superoxide dismutase [EC:1.15.1.1]
     Xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2]
     Ribonucleoside-diphosphate reductase [EC:1.17.4.1]
     Vitamin-K-epoxide reductase [EC:1.17.4.4]
     Thyroxine 5'-deiodinase [EC:1.21.99.4]
   Transferases (EC2)
   Hydrolases (EC3)
   Lyases (EC4)
   Isomerases (EC5)
   Ligases (EC6)
 
 Nucleic acids
 
 Not elsewhere classified

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Last updated: August 6, 2020

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