Target-based Classification of Drugs

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 G Protein-coupled receptors
 Ion channels
 Nuclear receptors
 Protein kinases
   Serine/threonine kinases
   Receptor serine/threonine kinases (RSTK)
   Receptor tyrosine kinases (RTK)
     EGFR family
     INSR family
     PDGFR family
       PDGFR [HSA:5156 5159] [KO:K04363 K05089]
       PDGFRA [HSA:5156] [KO:K04363]
       PDGFRA* [HSA_VAR:5156v2] [HSA:5156] [KO:K04363]
       FIP1L1-PDGFRA [HSA:5156] [KO:K04363]
         D08066  Imatinib (INN)
         D01441  Imatinib mesylate (USAN) <JP/US>
       PDGFRB [HSA:5159] [KO:K05089]
       KIT (CD117) [HSA:3815] [KO:K05091]
         D08066  Imatinib (INN)
         D01441  Imatinib mesylate (USAN) <JP/US>
         D08552  Sunitinib (INN)
         D06402  Sunitinib malate (JAN/USAN) <JP/US>
         D08524  Sorafenib (USAN/INN)
         D06272  Sorafenib tosylate (USAN) <JP/US>
         D03658  Dasatinib (JAN/INN)
         D06414  Dasatinib (USAN) <JP/US>
         D08953  Nilotinib (USAN/INN) <US>
         D06413  Nilotinib hydrochloride hydrate (JAN) <JP>
         D05380  Pazopanib hydrochloride (JAN/USAN) <JP/US>
         D10138  Regorafenib (USAN/INN)
         D10137  Regorafenib hydrate (JAN) <JP/US>
         D10229  Masitinib (INN)
         D05029  Midostaurin (JAN/USAN/INN) <US>
         D02937  Ancestim (USAN/INN)
         D05819  Semaxanib (USAN/INN)
         D06005  Tandutinib (USAN/INN)
         D06285  Vatalanib (USAN/INN)
         D06678  Motesanib (USAN)
         D08503  Toceranib (USAN)
         D08544  Toceranib phosphate (USAN)
         D08907  Dovitinib lactate (USAN)
         D08947  Motesanib diphosphate (USAN)
         D09864  Amuvatinib (USAN/INN)
         D09865  Amuvatinib hydrochloride (USAN)
         D11353  Ripretinib (USAN) <US>
       KIT* (CD117) [HSA_VAR:3815v1] [HSA:3815] [KO:K05091]
       FLT3 (CD135) [HSA:2322] [KO:K05092]
       FLT3* (CD135) [HSA_VAR:2322v1 2322v2] [HSA:2322] [KO:K05092]
       FLT3* (CD135) [HSA_VAR:2322v2] [HSA:2322] [KO:K05092]
     FGFR family
     VEGFR family
     MET family
     TRK family
     EPH family
     AXL family
     ALK family
     TIE family
     RET family
     CCK family
   Non-receptor tyrosine kinases
     SRC family
     ABL family
       ABL1 [HSA:25] [KO:K06619]
       BCR-ABL [HSA:25] [KO:K06619]
       BCR-ABL [HSA_VAR:25v1] [HSA:25] [KO:K06619]
         D01441  Imatinib mesylate (USAN) <JP/US>
       BCR-ABL [HSA_VAR:25v2] [HSA:25] [KO:K06619]
     SYK family
     JAK family
     FAK family
     Tec family
     InsR family
 Cytokines and receptors
 Cell surface molecules and ligands
 Nucleic acids
 Not elsewhere classified

Last updated: August 13, 2020

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