Target-based Classification of Drugs

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 G Protein-coupled receptors
 Ion channels
 Nuclear receptors
 Protein kinases
 Cytokines and receptors
 Cell surface molecules and ligands
   Oxidoreductases (EC1)
   Transferases (EC2)
   Hydrolases (EC3)
     Carboxylic-ester hydrolases [EC:3.1.1.-]
       LIPF [HSA:8513] [KO:K14452]
       LIPC [HSA:3990] [KO:K22283]
       PNLIP [HSA:5406] [KO:K14073]
       PNLIP [HSA:5406 5407 5408] [KO:K14073 K14074 K14075]
       PLA2G [HSA:26279 30814 391013 50487 5319 5320 5322 64600 81579 8399 84647] [KO:K01047]
       PLA2G4A [HSA:5321] [KO:K16342]
       PLA2G7 (LP-PLA2) [HSA:7941] [KO:K01062]
       ACHE [HSA:43] [KO:K01049]
         D08094  Itopride (INN)
         D02729  Itopride hydrochloride (JAN) <JP>
         D02292  Gallamine triethiodide (USP)
         D02565  Dimetacrine (INN)
         D08555  Tacrine (INN)
         D02068  Tacrine hydrochloride (USP)
         D07869  Donepezil (INN)
         D00670  Donepezil hydrochloride (JP17/USP) <JP/US>
         D03822  Rivastigmine (JAN/USP/INN) <JP/US>
         D02558  Rivastigmine tartrate <US>
         D04292  Galantamine (USAN/INN)
         D02173  Galantamine hydrobromide (JAN/USP) <JP/US>
         D09750  Ipidacrine hydrochloride hydrate (JAN)
         D08261  Neostigmine (BAN)
         D00995  Neostigmine bromide (JAN/USP/INN) <JP>
         D00998  Neostigmine methylsulfate (JP17/USP) <JP/US>
         D00487  Pyridostigmine bromide (JP17/USP/INN) <JP/US>
         D01228  Distigmine bromide (JP17/INN) <JP>
         D01001  Ambenonium chloride (JP17/INN) <JP>
         D02193  Echothiophate iodide (USP) <US>
         D00667  Demecarium bromide (USP/INN)
         D00196  Physostigmine (USP)
         D02418  Physostigmine salicylate (JAN/USP)
         D03826  Physostigmine sulfate (USP)
         D00043  Isoflurophate
         D10529  Paraoxon
         D00469  Pralidoxime chloride (USP) <US>
         D01572  Pralidoxime iodide (JAN/USAN) <JP>
         D05590  Pralidoxime mesylate (USAN)
         D05215  Obidoxime chloride (USAN)
         D00994  Edrophonium chloride (JP17/USP/INN) <JP>
         D03239  Ladostigil tartrate (USAN)
         D03751  Icopezil maleate (USAN)
         D03823  Quilostigmine (USAN/INN)
         D05981  Suronacrine maleate (USAN)
         D06288  Velnacrine maleate (USAN)
         D06365  Zifrosilone (USAN)
         D08838  Acotiamide hydrochloride (USAN) <JP>
         D09835  Zanapezil fumarate (JAN)
         D09917  Latrepirdine (USAN/INN)
         D09918  Latrepirdine dihydrochloride (USAN)
       BCHE [HSA:590] [KO:K01050]
       LIPA* [HSA_VAR:3988v1] [HSA:3988] [KO:K01052]
       LPL [HSA:4023] [KO:K01059]
       LPL* [HSA_VAR:4023v1] [HSA:4023] [KO:K01059]
       RPE65 [HSA:6121] [KO:K11158]
       RARRES3 (DDX58, RIG1) [HSA:5920] [KO:K23266]
     Phosphatases [EC:3.1.3.-]
     Phosphodiesterases [EC:3.1.4.-]
     Sulfatases [EC:3.1.6.-]
     Glycosidases [EC:3.2.1.-]
     ADP-ribosyl cyclase [EC:]
     Aminopeptidases [EC:3.4.11.-]
     Dipeptidases [EC:3.4.13.-]
     Peptidyl-peptidases [EC:3.4.14.-]
     Peptidyl-dipeptidases [EC:3.4.15.-]
     Metallocarboxypeptidases [EC:3.4.17.-]
     Serine peptidases [EC:3.4.21.-]
     Cysteine peptidases [EC:3.4.22.-]
     Aspartic peptidases [EC:3.4.23.-]
     Metallo peptidases [EC:3.4.24.- 3.4.17.-]
     Threonine peptidases [EC:3.4.25.-]
     Glutaminase [EC:]
     Histone deacetylase [EC:]
     Arginase [EC:]
     Adenosine deaminase [EC:]
     ATPase [EC:3.6.3.-]
   Lyases (EC4)
   Isomerases (EC5)
   Ligases (EC6)
 Nucleic acids
 Not elsewhere classified

Last updated: January 27, 2021

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