Target-based Classification of Drugs

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     Type
 G Protein-coupled receptors
   Rhodopsin family
     Acetylcholine (muscarinic)
     Adrenaline
     Dopamine
     Histamine
     Serotonin
     Angiotensin
     Bradykinin
     Cholecystokinin
     Endothelin
     Follicle stimulating hormone
     Ghrelin
     Gonadotropin-releasing hormone
     Lutropin-choriogonadotropic hormone
     Melanocortin
     Motilin
     Neuropeptide Y
     Opioid
     Orexin
     Oxytocin
     Relaxin
     Somatostatin
     Tachykinin
     Thrombin
     Thyrotropin-releasing hormone
     Vasopressin
     Purine / pyrimidine
     Adenosine
     Cysteinyl leukotriene
     Free fatty acid
     Leukotriene
     Prostaglandin
     Prostacyclin
     Sphingolipid
     Thromboxane
       TBXA2R [HSA:6915] [KO:K04264]
         D07140  Picotamide (BAN)
         D01896  Cilostazol (JP17/USP/INN) <JP/US>
         D01123  Seratrodast (JAN/USAN/INN) <JP>
         D01128  Ramatroban (JAN/INN) <JP>
         D03642  Daltroban (USAN/INN)
         D04500  Ifetroban (USAN/INN)
         D04501  Ifetroban sodium (USAN)
         D05727  Ridogrel (USAN/INN)
         D05970  Sulotroban (USAN/INN)
         D06077  Terbogrel (USAN/INN)
         D06280  Vapiprost hydrochloride (JAN/USAN)
         D09774  Imitrodast sodium (JAN)
         D09824  Domitroban calcium hydrate (JAN)
 
 
 
 
 
 
 
 
 
 
 
 
 
     Cannabinoid
     Melatonin
     Platelet activating factor
   Secretin receptor family
   Metabotropic glutamate receptor family
   Frizzled / Smoothened family
 
 Ion channels
 
 Nuclear receptors
 
 Protein kinases
 
 Cytokines and receptors
 
 Cell surface molecules and ligands
 
 Transporters
 
 Enzymes
   Oxidoreductases (EC1)
   Transferases (EC2)
   Hydrolases (EC3)
     Carboxylic-ester hydrolases [EC:3.1.1.-]
     Phosphatases [EC:3.1.3.-]
     Phosphodiesterases [EC:3.1.4.-]
       SMPD1* [HSA_VAR:6609v1] [HSA:6609] [KO:K12350]
       PDE [HSA:10846 27115 50940 5136 5137 5138 5139 5140 5141 5142 5143 5144 5150 5151 5153 8622] [KO:K18438 K18436 K13298 K13755 K18283 K19021 K13296 K13293 K18437]
       PDE [HSA:5153 5138 5139 5140 5141 5142 5143 5144 8654] [KO:K13755 K18283 K19021 K13296 K13293 K13762]
       PDE2A [HSA:5138] [KO:K18283]
       PDE3 [HSA:5139 5140] [KO:K19021 K13296]
         D01896  Cilostazol (JP17/USP/INN) <JP/US>
         D00231  Inamrinone (USP)
         D02084  Inamrinone ethylenelactate
         D00417  Milrinone (JAN/USP/INN) <JP>
         D02085  Milrinone lactate <US>
         D04004  Enoximone (USAN/INN)
         D04720  Levosimendan (USAN/INN)
         D07455  Anagrelide (INN/BAN)
         D02933  Anagrelide hydrochloride (USP)
         D10255  Anagrelide hydrochloride hydrate (JAN) <JP/US>
         D01385  Ibudilast (JP17/INN) <JP>
         D01133  Pimobendan (JAN/USAN/INN) <JP>
         D01198  Toborinone (JAN/USAN/INN)
         D01690  Vesnarinone (JAN/USAN/INN)
         D02042  Olprinone hydrochloride hydrate (JAN) <JP>
         D04508  Imazodan hydrochloride (USAN)
         D04529  Indolidan (USAN/INN)
         D04628  Isomazole hydrochloride (USAN)
         D04751  Lixazinone sulfate (USAN)
         D05514  Piroximone (USAN)
         D08294  Olprinone (INN)
         D09843  Beradilol monoethyl maleate (JAN)
         D11743  Ensifentrine (USAN/INN)
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
       PDE4 [HSA:5141 5142 5143 5144] [KO:K13293]
       PDE4A [HSA:5141] [KO:K13293]
       PDE5 [HSA:8654] [KO:K13762]
       PDE10A [HSA:10846] [KO:K18438]
       ENPP2 (ATX) [HSA:5168] [KO:K01122]
     Sulfatases [EC:3.1.6.-]
     Glycosidases [EC:3.2.1.-]
     ADP-ribosyl cyclase [EC:3.2.2.6]
     Aminopeptidases [EC:3.4.11.-]
     Dipeptidases [EC:3.4.13.-]
     Peptidyl-peptidases [EC:3.4.14.-]
     Peptidyl-dipeptidases [EC:3.4.15.-]
     Metallocarboxypeptidases [EC:3.4.17.-]
     Serine peptidases [EC:3.4.21.-]
     Cysteine peptidases [EC:3.4.22.-]
     Aspartic peptidases [EC:3.4.23.-]
     Metallo peptidases [EC:3.4.24.- 3.4.17.-]
     Threonine peptidases [EC:3.4.25.-]
     Glutaminase [EC:3.5.1.2]
     Histone deacetylase [EC:3.5.1.98]
     Arginase [EC:3.5.3.1]
     Adenosine deaminase [EC:3.5.4.4]
     ATPase [EC:3.6.3.-]
   Lyases (EC4)
   Isomerases (EC5)
   Ligases (EC6)
 
 Nucleic acids
 
 Not elsewhere classified

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Last updated: October 13, 2020

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