Target-based Classification of Drugs

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     Type
 G Protein-coupled receptors
   Rhodopsin family
     Acetylcholine (muscarinic)
     Adrenaline
       ADRA1 [HSA:148 147 146] [KO:K04135 K04136 K04137]
         D00095  Epinephrine (USP/INN) <JP/US>
         D00996  Epinephrine hydrochloride (JAN)
         D02149  Epinephrine bitartrate (JAN/USP)
         D02774  Adrenalone (USAN/INN)
         D07560  Adrenalone hydrochloride
         D02910  Amiodarone (USAN/INN)
         D00636  Amiodarone hydrochloride (JP17/USP) <JP/US>
         D02537  Dronedarone (INN)
         D03914  Dronedarone hydrochloride (USP) <US>
         D07931  Etilefrine (INN)
         D01573  Etilefrine hydrochloride (JP17) <JP>
         D00076  Noradrenaline (JP17) <JP>
         D05206  Norepinephrine bitartrate (USP) <US>
         D08284  Norepinephrine hydrochoride
         D09794  Norepinephrine hydrochloride (JAN)
         D08365  Phenylephrine (INN)
         D00511  Phenylephrine hydrochloride (JP17/USP) <JP/US>
         D08366  Phenylephrine tartrate
         D08966  Phenylephrine bitartrate (USP)
         D08192  Metaraminol (INN)
         D01019  Metaraminol bitartrate (JAN/USP)
         D08201  Methoxamine (BAN)
         D01020  Methoxamine hydrochloride (JAN)
         D08220  Midodrine (INN)
         D01307  Midodrine hydrochloride (JAN/USP) <JP/US>
         D00124  Ephedrine (USP)
         D01386  Ephedrine hydrochloride (JP17/USP) <JP>
         D04018  Ephedrine sulfate (USP) <US>
         D01277  Droxidopa (JP17/USAN/INN) <JP/US>
         D08411  Prazosin (INN)
         D00609  Prazosin hydrochloride (JP17/USP) <JP/US>
         D04531  Indoramin (USAN/INN)
         D04532  Indoramin hydrochloride (USAN)
         D08212  Trimazosin (INN)
         D06234  Trimazosin hydrochloride (USAN)
         D07874  Doxazosin (INN)
         D00608  Doxazosin mesylate (USP) <JP/US>
         D01333  Urapidil (JP17/INN) <JP>
         D08662  Urapidil hydrochloride
         D08362  Phentolamine (INN)
         D00509  Phentolamine mesylate (USP) <JP/US>
         D08614  Tolazoline (INN)
         D00997  Tolazoline hydrochloride (JAN/USP)
         D02268  Ergoloid mesylates (USP)
         D01290  Nicergoline (JP17/USAN/INN) <JP>
         D08271  Nicergoline tartrate
         D07834  Dihydroergocristine (BAN)
         D07833  Dihydroergocristine mesilate (BAN)
         D08358  Phenoxybenzamine (INN)
         D00507  Phenoxybenzamine hydrochloride (USP) <US>
         D08239  Moxisylyte (INN)
         D01571  Moxisylyte hydrochloride (JAN)
         D08064  Ifenprodil (INN)
         D01445  Ifenprodil tartrate (JP17) <JP>
         D01369  Bevantolol hydrochloride (JAN/USAN) <JP>
         D08106  Labetalol (INN) <US>
         D00600  Labetalol hydrochloride (JP17/USP) <JP/US>
         D00255  Carvedilol (JP17/USP/INN) <JP/US>
         D03415  Carvedilol phosphate (USAN) <US>
         D08207  Methylergometrine (INN)
         D00680  Methylergonovine maleate (USP) <JP/US>
         D07906  Ergotamine (INN)
         D07905  Ergometrine (INN)
         D01163  Ergonovine maleate (USP) <JP>
         D08560  Tamsulosin (INN)
         D01024  Tamsulosin hydrochloride (JP17/USP) <JP/US>
         D08569  Terazosin (INN)
         D00610  Terazosin hydrochloride (USP) <JP/US>
         D00679  Ergotamine tartrate (JP17/USP) <US>
         D01485  Propericiazine (JAN) <JP>
         D00308  Droperidol (JP17/USP/INN) <JP/US>
         D00454  Olanzapine (JAN/USP/INN) <JP/US>
         D06623  Olanzapine pamoate (USAN) <US>
         D08257  Nefazodone (INN)
         D00819  Nefazodone hydrochloride (USP) <US>
         D08578  Tetryzoline (INN)
         D00756  Tetrahydrozoline nitrate (JAN)
         D01023  Tetrahydrozoline hydrochloride (JAN/USP)
         D08684  Xylometazoline (INN)
         D00757  Xylometazoline hydrochloride (USP)
         D08253  Naphazoline (INN)
         D00743  Naphazoline hydrochloride (JP17/USP) <US>
         D01021  Naphazoline nitrate (JP17) <JP>
         D08624  Tramazoline (INN)
         D01347  Tramazoline hydrochloride (JAN/USAN) <JP>
         D08368  Phenylpropanolamine (INN)
         D01224  Phenylpropanolamine hydrochloride (JAN/USP)
         D05466  Phenylpropanolamine polistirex (USAN)
         D08449  Pseudoephedrine (INN)
         D00485  Pseudoephedrine hydrochloride (USP)
         D05648  Pseudoephedrine polistirex (USAN)
         D05649  Pseudoephedrine sulfate (USP)
         D02349  Dipivefrin (USAN)
         D01017  Dipivefrin hydrochloride (JAN/USP) <JP>
         D08115  Levobunolol (INN)
         D01025  Levobunolol hydrochloride (JAN/USP) <JP/US>
         D07775  Dapiprazole (INN)
         D03648  Dapiprazole hydrochloride (USAN) <US>
         D00607  Guanadrel sulfate (USAN)
         D01171  Monatepil maleate (JAN/USAN)
         D01444  Bunitrolol hydrochloride (JAN)
         D01469  Amosulalol hydrochloride (JP17) <JP>
         D01674  Naftopidil (JP17/INN) <JP>
         D01691  Nipradilol (JAN/INN) <JP>
         D01830  Arotinolol hydrochloride (JP17) <JP>
         D01887  Bunazosin hydrochloride (JP17) <JP>
         D01952  L-Methylephedrine hydrochloride (JAN)
         D02109  dl-Methylephedrine hydrochloride (JP17) <JP>
         D02568  Flesinoxan (INN)
         D02901  Amidephrine mesylate (USAN)
         D03887  Domazoline fumarate (USAN)
         D04026  Epinephryl borate (USP)
         D05228  Octodrine (USAN/INN)
         D05395  Pelanserin hydrochloride (USAN)
         D05637  Propylhexedrine (USP/INN)
         D05688  Racepinephrine (USP/INN)
         D05689  Racepinephrine hydrochloride (USP)
         D07451  Amosulalol (INN)
         D07465  Arotinolol (INN)
         D07550  Bunazosin (INN)
         D08029  Guanadrel (INN)
         D08206  Methylephedrine (BAN)
         D08444  Propylhexedrine hydrochloride
         D08982  Racephedrine Hydrochloride (USAN)
         D09842  dl-Methylephedrine saccharinate (JAN)
         D11585  Terazosin hydrochloride anhydrous <US>
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
       ADRA1A [HSA:148] [KO:K04135]
       ADRA1D [HSA:146] [KO:K04137]
       ADRA2 [HSA:150 151 152] [KO:K04138 K04139 K04140]
       ADRA2A [HSA:150] [KO:K04138]
       ADRA2B [HSA:151] [KO:K04139]
       ADRB [HSA:153 154 155] [KO:K04141 K04142 K04143]
       ADRB1 [HSA:153] [KO:K04141]
       ADRB2 [HSA:154] [KO:K04142]
       ADRB3 [HSA:155] [KO:K04143]
     Dopamine
     Histamine
     Serotonin
       HTR1 [HSA:3350 3351 3352 3354 3355] [KO:K04153]
       HTR1A [HSA:3350] [KO:K04153]
         D07906  Ergotamine (INN)
         D02577  Flibanserin (USAN/INN) <US>
         D00679  Ergotamine tartrate (JP17/USP) <US>
         D02357  Methysergide (USAN/INN)
         D00681  Methysergide maleate (USP)
         D08385  Pipotiazine (INN)
         D02680  Pipotiazine palmitate (USAN)
         D02995  Asenapine maleate (JAN/USAN) <JP/US>
         D01164  Aripiprazole (JAN/USP/INN) <JP/US>
         D10355  Aripiprazole cavoxil (USAN)
         D10364  Aripiprazole lauroxil (USAN) <US>
         D10516  Aripiprazole hydrate (JAN) <JP/US>
         D09997  Cariprazine (USAN/INN)
         D09876  Cariprazine hydrochloride (JAN/USAN) <US>
         D10309  Brexpiprazole (JAN/USAN/INN) <JP/US>
         D07593  Buspirone (INN)
         D00702  Buspirone hydrochloride (USP) <US>
         D04314  Gepirone hydrochloride (USAN)
         D09698  Vilazodone (USAN/INN)
         D09699  Vilazodone hydrochloride (USAN) <US>
         D10184  Vortioxetine (USAN)
         D10185  Vortioxetine hydrobromide (JAN/USAN) <JP/US>
         D06327  Xaliproden (USAN)
         D01537  Xaliproden hydrochloride (JAN)
         D01992  Tandospirone citrate (JAN/USAN) <JP>
         D02568  Flesinoxan (INN)
         D02569  Sunepitron hydrochloride (USAN)
         D02576  Eptapirone (INN)
         D02688  Tiospirone hydrochloride (USAN)
         D02767  Adatanserin hydrochloride (USAN)
         D03121  Binospirone mesylate (USAN)
         D04611  Ipsapirone hydrochloride (USAN)
         D04683  Lecozotan hydrochloride (USAN)
         D05804  Sarizotan hydrochloride (USAN)
         D06354  Zalospirone hydrochloride (USAN)
         D06566  Bifeprunox (USAN/INN)
         D06567  Bifeprunox mesylate (USAN)
         D08561  Tandospirone (INN)
         D09358  Naluzotan (USAN/INN)
         D09359  Naluzotan hydrochloride (USAN)
         D09366  Pardoprunox hydrochloride (USAN)
         D09397  Pardoprunox (USAN/INN)
         D11830  Ralmitaront (USAN/INN)
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
       HTR1B [HSA:3351] [KO:K04153]
       HTR1D [HSA:3352] [KO:K04153]
       HTR1F [HSA:3355] [KO:K04153]
       HTR2 [HSA:3356 3357 3358] [KO:K04157]
       HTR2A [HSA:3356] [KO:K04157]
       HTR2C [HSA:3358] [KO:K04157]
       HTR4 [HSA:3360] [KO:K04160]
       HTR6 [HSA:3362] [KO:K04162]
       HTR7 [HSA:3363] [KO:K04163]
     Angiotensin
     Bradykinin
     Cholecystokinin
     Endothelin
     Follicle stimulating hormone
     Ghrelin
     Gonadotropin-releasing hormone
     Lutropin-choriogonadotropic hormone
     Melanocortin
     Motilin
     Neuropeptide Y
     Opioid
     Orexin
     Oxytocin
     Relaxin
     Somatostatin
     Tachykinin
     Thrombin
     Thyrotropin-releasing hormone
     Vasopressin
     Purine / pyrimidine
     Adenosine
     Cysteinyl leukotriene
     Free fatty acid
     Leukotriene
     Prostaglandin
     Prostacyclin
     Sphingolipid
     Thromboxane
     Cannabinoid
     Melatonin
     Platelet activating factor
   Secretin receptor family
   Metabotropic glutamate receptor family
   Frizzled / Smoothened family
 
 Ion channels
 
 Nuclear receptors
 
 Protein kinases
 
 Cytokines and receptors
 
 Cell surface molecules and ligands
 
 Transporters
 
 Enzymes
 
 Nucleic acids
 
 Not elsewhere classified

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Last updated: November 20, 2020

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