Target-based Classification of Drugs

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     Type
 G Protein-coupled receptors
 
 Ion channels
 
 Nuclear receptors
 
 Protein kinases
 
 Cytokines and receptors
 
 Cell surface molecules and ligands
 
 Transporters
 
 Enzymes
   Oxidoreductases (EC1)
     Dehydrogenases [EC:1.1.1.-]
     Dehydrogenases [EC:1.2.1.-]
     Dehydrogenases [EC:1.3.-.-]
     Amine oxidases [EC:1.4.3.-]
     Dihydrofolate reductase [EC:1.5.1.3]
     NAD(P)H dehydrogenase [EC:1.6.5.2]
     Thyroid peroxidase [EC:1.11.1.8]
     Dioxygenases [EC:1.13.11.-]
     Prolyl 4-hydroxylase [EC:1.14.11.2]
     HIF hydroxylase [EC:1.14.11.29]
     Nitic oxide synthase [EC:1.14.13.39]
     Cytochrome P450 [EC:1.14.14.-]
     Other monooxygenases [EC:1.14.16.- 1.14.17.- 1.14.18.-]
     Prostaglandin synthase [EC:1.14.99.1]
     Xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2]
     Ribonucleoside-diphosphate reductase [EC:1.17.4.1]
       RRM1 [HSA:6240] [KO:K10807]
         D01370  Cladribine (JAN/USAN/INN) <JP/US>
         D07966  Fludarabine (INN)
         D01907  Fludarabine phosphate (JAN/USP) <JP/US>
         D03546  Clofarabine (JAN/USAN/INN) <JP/US>
         D02368  Gemcitabine (USAN/INN)
         D01155  Gemcitabine hydrochloride (JAN/USAN) <JP/US>
         D10222  Gemcitabine elaidate (USAN/INN)
         D03378  Caracemide (USAN)
         D06100  Tezacitabine (USAN)
 
 
 
 
 
 
 
 
 
       RRM2 [HSA:6241] [KO:K10808]
     Vitamin-K-epoxide reductase [EC:1.17.4.4]
     Thyroxine 5'-deiodinase [EC:1.21.99.4]
   Transferases (EC2)
     Methyltransferases [EC:2.1.1.-]
     Acyltransferases [EC:2.3.1.-]
     gamma-Glutamyltransferase [EC:2.3.2.2]
     E3 ubiquitin-protein ligase [EC:2.3.2.27]
     ATP citrate synthase [EC:2.3.3.8]
     Hexosyltransferases [EC:2.4.1.-]
     Pentosyltransferases [EC:2.4.2.-]
     Alkyl/Aryl transferases [EC:2.5.1.-]
     Aminotransferase [EC:2.6.1.-]
     Phosphotransferase [EC:2.7.1.-]
     DNA polymerase [EC:2.7.7.7]
       POLA [HSA:5422 23649] [KO:K02320 K02321]
         D03546  Clofarabine (JAN/USAN/INN) <JP/US>
 
     Reverse transcriptase [EC:2.7.7.49]
   Hydrolases (EC3)
   Lyases (EC4)
   Isomerases (EC5)
   Ligases (EC6)
 
 Nucleic acids
 
 Not elsewhere classified

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Last updated: September 20, 2019

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