Target-based Classification of Drugs

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 G Protein-coupled receptors
   Rhodopsin family
     Acetylcholine (muscarinic)
       DRD [HSA:1812 1813 1814 1815 1816] [KO:K04144 K04145 K04146 K04147 K05840]
       DRD1 [HSA:1812] [KO:K04144]
       DRD2 [HSA:1813] [KO:K04145]
         D00726  Metoclopramide (JP17/INN) <JP>
         D02213  Metoclopramide hydrochloride (JAN) <JP/US>
         D05008  Metoclopramide hydrochloride (USP) <US>
         D01745  Domperidone (JP17/USAN/INN) <JP>
         D07868  Domperidone maleate
         D07101  Bromopride (INN)
         D07102  Alizapride (INN)
         D07563  Alizapride hydrochloride
         D03534  Clebopride (USAN)
         D01742  Clebopride malate (JP17)
         D08094  Itopride (INN)
         D02729  Itopride hydrochloride (JAN) <JP>
         D05010  Metopimazine (USAN/INN)
         D04488  Ibopamine (USAN/INN)
         D08057  Ibopamine hydrochloride
         D03165  Bromocriptine (USAN/INN)
         D00780  Bromocriptine mesylate (USP) <JP/US>
         D08132  Lisuride (INN)
         D01462  Lisuride maleate (JAN)
         D00987  Cabergoline (JAN/USP/INN) <JP/US>
         D07217  Quinagolide (INN/BAN)
         D08457  Quinagolide hydrochloride (BAN)
         D01348  Terguride (JAN/INN)
         D07460  Apomorphine (BAN)
         D02004  Apomorphine hydrochloride (USP) <JP/US>
         D08339  Pergolide (INN)
         D00502  Pergolide mesylate (USP) <JP>
         D07836  Dihydroergocryptine mesilate
         D08489  Ropinirole (USAN/INN)
         D00784  Ropinirole hydrochloride (JAN/USP) <JP/US>
         D05575  Pramipexole (USAN/INN)
         D00559  Pramipexole dihydrochloride (USP) <JP/US>
         D07305  Piribedil (INN)
         D05768  Rotigotine (JAN/USAN/INN) <JP/US>
         D00270  Chlorpromazine (USP/INN)
         D00789  Chlorpromazine hydrochloride (JP17/USP) <JP/US>
         D03274  Chlorpromazine hibenzate (JAN)
         D04034  Chlorpromazine phenolphthalinate (JAN) <JP>
         D09819  Chlorpromazine tannate (JAN)
         D00403  Methotrimeprazine (USP)
         D01520  Levomepromazine hydrochloride (JAN/USAN) <JP>
         D02248  Levomepromazine maleate (JP17/USAN) <JP>
         D08430  Promazine (INN)
         D00797  Promazine hydrochloride (USP)
         D07065  Acepromazine (INN)
         D02604  Acepromazine maleate (USP)
         D00390  Triflupromazine (USP/INN)
         D00800  Triflupromazine hydrochloride (JAN/USP)
         D07977  Fluphenazine (INN)
         D00791  Fluphenazine hydrochloride (JAN/USP) <US>
         D00792  Fluphenazine enanthate (JP17/USP)
         D00793  Fluphenazine decanoate (JAN/USP) <JP/US>
         D02163  Fluphenazine maleate (JAN) <JP>
         D00503  Perphenazine (JP17/USP/INN) <JP/US>
         D02037  Perphenazine maleate (JP17) <JP>
         D04038  Perphenazine fendizoate (JAN) <JP>
         D04965  Perphenazine hydrochloride <JP>
         D08341  Perphenazine decanoate
         D08342  Perphenazine enantate
         D00493  Prochlorperazine (JAN/USP/INN) <US>
         D00479  Prochlorperazine maleate (JP17/USP) <JP/US>
         D02022  Prochlorperazine mesilate (JAN) <JP>
         D02609  Prochlorperazine edisylate (USP) <US>
         D08636  Trifluoperazine (INN)
         D00799  Trifluoperazine hydrochloride (JAN/USP) <US>
         D01448  Trifluoperazine maleate (JAN)
         D00788  Acetophenazine maleate (USAN)
         D08585  Thioproperazine (INN)
         D01447  Thioproperazine mesilate (JAN)
         D01412  Perazine maleate (JAN)
         D01860  Perazine dimalonate (JAN)
         D02608  Perazine fendizoate (JAN)
         D01485  Propericiazine (JAN) <JP>
         D00373  Thioridazine (USP/INN)
         D00798  Thioridazine hydrochloride (JP17/USP) <US>
         D02671  Mesoridazine (USAN/INN)
         D00795  Mesoridazine besylate (USP)
         D08385  Pipotiazine (INN)
         D02680  Pipotiazine palmitate (USAN)
         D00136  Haloperidol (JP17/USP/INN) <JP/US>
         D01898  Haloperidol decanoate (JAN/USP) <JP/US>
         D08035  Haloperidol lactate <US>
         D02625  Trifluperidol (USAN/INN)
         D08637  Trifluperidol hydrochloride
         D07309  Melperone (INN)
         D08172  Melperone hydrochloride
         D02623  Moperone (INN)
         D01105  Moperone hydrochloride (JAN)
         D02622  Pipamperone (USAN/INN)
         D01482  Pipamperone hydrochloride (JAN) <JP>
         D01101  Bromperidol (JAN/USAN/INN) <JP>
         D02626  Bromperidol decanoate (USAN)
         D02627  Benperidol (USAN/INN)
         D00308  Droperidol (JP17/USP/INN) <JP/US>
         D08226  Molindone (INN)
         D00796  Molindone hydrochloride (USP) <US>
         D00561  Sertindole (USAN/INN)
         D08687  Ziprasidone (INN)
         D01939  Ziprasidone hydrochloride (USP) <US>
         D02100  Ziprasidone mesylate (USAN) <US>
         D04820  Lurasidone hydrochloride (JAN/USAN) <JP/US>
         D01044  Flupentixol (INN)
         D02236  Flupentixol dihydrochloride (JAN)
         D07976  Flupentixol decanoate
         D02613  Clopenthixol (USAN)
         D00790  Chlorprothixene (JAN/USAN/INN)
         D02162  Chlorprothixene hydrochloride (JAN)
         D07686  Chlorprothixene acetate
         D07687  Chlorprothixene citrate
         D00374  Thiothixene (USP) <US>
         D02612  Thiothixene hydrochloride (USP)
         D03556  Zuclopenthixol (INN)
         D08691  Zuclopenthixol acetate
         D08692  Zuclopenthixol decanoate
         D08693  Zuclopenthixol dihydrochloride
         D00560  Pimozide (JP17/USP/INN) <JP/US>
         D02340  Loxapine (USAN/INN) <US>
         D00794  Loxapine succinate (USP) <US>
         D08148  Loxapine hydrochloride
         D00454  Olanzapine (JAN/USP/INN) <JP/US>
         D06623  Olanzapine pamoate (USAN) <US>
         D08456  Quetiapine (INN)
         D00458  Quetiapine fumarate (JP17/USP) <JP/US>
         D11769  Asenapine (INN) <US>
         D02995  Asenapine maleate (JAN/USAN) <JP/US>
         D01226  Sulpiride (JP17/USAN/INN) <JP>
         D08549  Sultopride (INN)
         D02208  Sultopride hydrochloride (JAN) <JP>
         D08590  Tiapride (INN)
         D01522  Tiapride hydrochloride (JP17) <JP>
         D02682  Remoxipride (USAN)
         D02683  Remoxipride hydrochloride (USAN)
         D07310  Amisulpride (INN) <US>
         D07312  Levosulpiride (INN)
         D00426  Risperidone (JP17/USP/INN) <JP/US>
         D08235  Mosapramine (INN)
         D01548  Mosapramine hydrochloride (JAN) <JP>
         D01321  Zotepine (JAN/INN) <JP>
         D01164  Aripiprazole (JAN/USP/INN) <JP/US>
         D10355  Aripiprazole cavoxil (USAN)
         D10364  Aripiprazole lauroxil (USAN) <US>
         D10516  Aripiprazole hydrate (JAN) <JP/US>
         D05339  Paliperidone (JAN/USP/INN) <JP/US>
         D05340  Paliperidone palmitate (JAN/USAN) <JP/US>
         D02666  Iloperidone (USAN/INN) <US>
         D09997  Cariprazine (USAN/INN)
         D09876  Cariprazine hydrochloride (JAN/USAN) <US>
         D10309  Brexpiprazole (JAN/USAN/INN) <JP/US>
         D07593  Buspirone (INN)
         D00702  Buspirone hydrochloride (USP) <US>
         D08297  Opipramol (INN)
         D01477  Opipramol hydrochloride (JAN/USAN)
         D02354  Thiethylperazine (USAN/INN)
         D01130  Thiethylperazine maleate (JAN/USP)
         D02610  Thiethylperazine malate (JAN)
         D01051  Spiperone (JAN/USAN) <JP>
         D01176  Blonanserin (JAN/INN) <JP>
         D01468  Nemonapride (JAN/INN) <JP>
         D01505  Talipexole hydrochloride (JAN) <JP>
         D02035  Timiperone (JAN) <JP>
         D02371  Clocapramine hydrochloride hydrate (JP17) <JP>
         D02372  Perospirone hydrochloride hydrate (JAN) <JP>
         D02605  Methoxypromazine maleate
         D02634  Alentemol hydrobromide (USAN)
         D02641  Butaclamol hydrochloride (USAN)
         D02644  Carphenazine maleate (USAN)
         D02645  Carvotroline hydrochloride (USAN)
         D02670  Mazapertine succinate (USAN)
         D02675  Ocaperidone (USAN)
         D02681  Piquindone hydrochloride (USAN)
         D02688  Tiospirone hydrochloride (USAN)
         D03214  Aplindore fumarate (USAN)
         D03494  Ciladopa hydrochloride (USAN)
         D04693  Lergotrile (USAN/INN)
         D04694  Lergotrile mesylate (USAN)
         D05124  Naxagolide hydrochloride (USAN)
         D05677  Quinelorane hydrochloride (USAN)
         D05682  Quinpirole hydrochloride (USAN)
         D05690  Raclopride C11 (USAN)
         D05804  Sarizotan hydrochloride (USAN)
         D05832  Sibenadet hydrochloride (USAN)
         D06566  Bifeprunox (USAN/INN)
         D06567  Bifeprunox mesylate (USAN)
         D07718  Clocapramine (INN)
         D07835  Dihydroergocryptine
         D08558  Talipexole (INN)
         D09366  Pardoprunox hydrochloride (USAN)
         D09397  Pardoprunox (USAN/INN)
         D09953  Pridopidine (USAN/INN)
         D09954  Pridopidine hydrochloride (USAN)
         D10329  Zicronapine (USAN/INN)
         D10495  Zicronapine succinate (USAN)
         D11169  Lumateperone (USAN/INN)
         D11170  Lumateperone tosylate (USAN) <US>
       DRD3 [HSA:1814] [KO:K04146]
       DRD4 [HSA:1815] [KO:K04147]
       DRD5 [HSA:1816] [KO:K05840]
     Follicle stimulating hormone
     Gonadotropin-releasing hormone
     Lutropin-choriogonadotropic hormone
     Neuropeptide Y
     Thyrotropin-releasing hormone
     Purine / pyrimidine
     Cysteinyl leukotriene
     Free fatty acid
     Platelet activating factor
   Secretin receptor family
   Metabotropic glutamate receptor family
   Frizzled / Smoothened family
 Ion channels
 Nuclear receptors
 Protein kinases
 Cytokines and receptors
 Cell surface molecules and ligands
   Oxidoreductases (EC1)
   Transferases (EC2)
   Hydrolases (EC3)
     Carboxylic-ester hydrolases [EC:3.1.1.-]
       LIPF [HSA:8513] [KO:K14452]
       LIPC [HSA:3990] [KO:K22283]
       PNLIP [HSA:5406] [KO:K14073]
       PNLIP [HSA:5406 5407 5408] [KO:K14073 K14074 K14075]
       PLA2G [HSA:26279 30814 391013 50487 5319 5320 5322 64600 81579 8399 84647] [KO:K01047]
       PLA2G4A [HSA:5321] [KO:K16342]
       PLA2G7 (LP-PLA2) [HSA:7941] [KO:K01062]
       ACHE [HSA:43] [KO:K01049]
         D08094  Itopride (INN)
         D02729  Itopride hydrochloride (JAN) <JP>
         D02292  Gallamine triethiodide (USP)
         D02565  Dimetacrine (INN)
         D08555  Tacrine (INN)
         D02068  Tacrine hydrochloride (USP)
         D07869  Donepezil (INN)
         D00670  Donepezil hydrochloride (JP17/USP) <JP/US>
         D03822  Rivastigmine (JAN/USP/INN) <JP/US>
         D02558  Rivastigmine tartrate <US>
         D04292  Galantamine (USAN/INN)
         D02173  Galantamine hydrobromide (JAN/USP) <JP/US>
         D09750  Ipidacrine hydrochloride hydrate (JAN)
         D08261  Neostigmine (BAN)
         D00995  Neostigmine bromide (JAN/USP/INN) <JP>
         D00998  Neostigmine methylsulfate (JP17/USP) <JP/US>
         D00487  Pyridostigmine bromide (JP17/USP/INN) <JP/US>
         D01228  Distigmine bromide (JP17/INN) <JP>
         D01001  Ambenonium chloride (JP17/INN) <JP>
         D02193  Echothiophate iodide (USP) <US>
         D00667  Demecarium bromide (USP/INN)
         D00196  Physostigmine (USP)
         D02418  Physostigmine salicylate (JAN/USP)
         D03826  Physostigmine sulfate (USP)
         D00043  Isoflurophate
         D10529  Paraoxon
         D00469  Pralidoxime chloride (USP) <US>
         D01572  Pralidoxime iodide (JAN/USAN) <JP>
         D05590  Pralidoxime mesylate (USAN)
         D05215  Obidoxime chloride (USAN)
         D00994  Edrophonium chloride (JP17/USP/INN) <JP>
         D03239  Ladostigil tartrate (USAN)
         D03751  Icopezil maleate (USAN)
         D03823  Quilostigmine (USAN/INN)
         D05981  Suronacrine maleate (USAN)
         D06288  Velnacrine maleate (USAN)
         D06365  Zifrosilone (USAN)
         D08838  Acotiamide hydrochloride (USAN) <JP>
         D09835  Zanapezil fumarate (JAN)
         D09917  Latrepirdine (USAN/INN)
         D09918  Latrepirdine dihydrochloride (USAN)
       BCHE [HSA:590] [KO:K01050]
       LIPA* [HSA_VAR:3988v1] [HSA:3988] [KO:K01052]
       LPL [HSA:4023] [KO:K01059]
       LPL* [HSA_VAR:4023v1] [HSA:4023] [KO:K01059]
       RPE65 [HSA:6121] [KO:K11158]
       RARRES3 (DDX58, RIG1) [HSA:5920] [KO:K23266]
     Phosphatases [EC:3.1.3.-]
     Phosphodiesterases [EC:3.1.4.-]
     Sulfatases [EC:3.1.6.-]
     Glycosidases [EC:3.2.1.-]
     ADP-ribosyl cyclase [EC:]
     Aminopeptidases [EC:3.4.11.-]
     Dipeptidases [EC:3.4.13.-]
     Peptidyl-peptidases [EC:3.4.14.-]
     Peptidyl-dipeptidases [EC:3.4.15.-]
     Metallocarboxypeptidases [EC:3.4.17.-]
     Serine peptidases [EC:3.4.21.-]
     Cysteine peptidases [EC:3.4.22.-]
     Aspartic peptidases [EC:3.4.23.-]
     Metallo peptidases [EC:3.4.24.- 3.4.17.-]
     Threonine peptidases [EC:3.4.25.-]
     Glutaminase [EC:]
     Histone deacetylase [EC:]
     Arginase [EC:]
     Adenosine deaminase [EC:]
     ATPase [EC:3.6.3.-]
   Lyases (EC4)
   Isomerases (EC5)
   Ligases (EC6)
 Nucleic acids
 Not elsewhere classified

Last updated: December 2, 2020

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