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Type |
 G Protein-coupled receptors
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Ion channels
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Nuclear receptors
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 Protein kinases
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Serine/threonine kinases
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AGC group
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CAMK group
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CMGC group
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STE group
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TKL group
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BRAF [HSA:673] [KO:K04365]
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 D10064 Dabrafenib (USAN)
D08524 Sorafenib (USAN/INN)
D06272 Sorafenib tosylate (USAN) <JP/US>
D10138 Regorafenib (USAN/INN)
D10137 Regorafenib hydrate (JAN) <JP/US>
D11410 Lifirafenib (USAN/INN)
D11411 Lifirafenib maleate (USAN)
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BRAF* [HSA_VAR:673v1] [HSA:673] [KO:K04365]
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RAF1 [HSA:5894] [KO:K04366]
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D08524 Sorafenib (USAN/INN)
D06272 Sorafenib tosylate (USAN) <JP/US>
D10138 Regorafenib (USAN/INN)
D10137 Regorafenib hydrate (JAN) <JP/US>
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Other
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Receptor serine/threonine kinases (RSTK)
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Receptor tyrosine kinases (RTK)
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EGFR family
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INSR family
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PDGFR family
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PDGFR [HSA:5156 5159] [KO:K04363 K05089]
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PDGFRA [HSA:5156] [KO:K04363]
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PDGFRA* [HSA_VAR:5156v2] [HSA:5156] [KO:K04363]
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FIP1L1-PDGFRA [HSA:5156] [KO:K04363]
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PDGFRB [HSA:5159] [KO:K05089]
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D03065 Becaplermin (USAN/INN) <US>
D03658 Dasatinib (JAN/INN)
D06414 Dasatinib (USAN) <JP/US>
D08524 Sorafenib (USAN/INN)
D06272 Sorafenib tosylate (USAN) <JP/US>
D10138 Regorafenib (USAN/INN)
D10137 Regorafenib hydrate (JAN) <JP/US>
D06005 Tandutinib (USAN/INN)
D06285 Vatalanib (USAN/INN)
D08907 Dovitinib lactate (USAN)
D08947 Motesanib diphosphate (USAN)
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|
KIT (CD117) [HSA:3815] [KO:K05091]
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D08066 Imatinib (INN)
D01441 Imatinib mesylate (USAN) <JP/US>
D03658 Dasatinib (JAN/INN)
D06414 Dasatinib (USAN) <JP/US>
D08953 Nilotinib (USAN/INN)
D06413 Nilotinib hydrochloride hydrate (JAN) <JP/US>
D08552 Sunitinib (INN)
D06402 Sunitinib malate (JAN/USAN) <JP/US>
D08524 Sorafenib (USAN/INN)
D06272 Sorafenib tosylate (USAN) <JP/US>
D05380 Pazopanib hydrochloride (JAN/USAN) <JP/US>
D10138 Regorafenib (USAN/INN)
D10137 Regorafenib hydrate (JAN) <JP/US>
D10229 Masitinib (INN)
D05029 Midostaurin (JAN/USAN/INN) <US>
D11353 Ripretinib (USAN) <US>
D02937 Ancestim (USAN/INN)
D05819 Semaxanib (USAN/INN)
D06005 Tandutinib (USAN/INN)
D06285 Vatalanib (USAN/INN)
D06678 Motesanib (USAN)
D08503 Toceranib (USAN)
D08544 Toceranib phosphate (USAN)
D08907 Dovitinib lactate (USAN)
D08947 Motesanib diphosphate (USAN)
D09864 Amuvatinib (USAN/INN)
D09865 Amuvatinib hydrochloride (USAN)
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|
KIT* (CD117) [HSA_VAR:3815v1] [HSA:3815] [KO:K05091]
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FLT3 (CD135) [HSA:2322] [KO:K05092]
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D08552 Sunitinib (INN)
D06402 Sunitinib malate (JAN/USAN) <JP/US>
D08524 Sorafenib (USAN/INN)
D06272 Sorafenib tosylate (USAN) <JP/US>
D09955 Quizartinib (USAN/INN)
D10709 Gilteritinib (USAN/INN)
D04696 Lestaurtinib (USAN/INN)
D05819 Semaxanib (USAN/INN)
D06005 Tandutinib (USAN/INN)
D08279 Tozasertib (USAN)
D08344 Tozasertib lactate (USAN)
D08907 Dovitinib lactate (USAN)
D10102 Crenolanib (USAN)
D10103 Crenolanib besylate (USAN)
D11599 Zotiraciclib (USAN)
D11600 Zotiraciclib citrate (USAN)
D11768 Pacritinib (USAN/INN)
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|
FLT3* (CD135) [HSA_VAR:2322v1 2322v2] [HSA:2322] [KO:K05092]
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FLT3* (CD135) [HSA_VAR:2322v2] [HSA:2322] [KO:K05092]
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FGFR family
|
VEGFR family
|
VEGFR1 (FLT1) [HSA:2321] [KO:K05096]
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VEGFR2 (KDR) [HSA:3791] [KO:K05098]
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D03218 Axitinib (JAN/USAN) <JP/US>
D08881 Cediranib (USAN/INN)
D08883 Cediranib maleate (JAN/USAN)
D09683 Tivozanib (USAN/INN)
D10190 Tivozanib hydrochloride (USAN)
D08552 Sunitinib (INN)
D06402 Sunitinib malate (JAN/USAN) <JP/US>
D08524 Sorafenib (USAN/INN)
D06272 Sorafenib tosylate (USAN) <JP/US>
D05380 Pazopanib hydrochloride (JAN/USAN) <JP/US>
D06407 Vandetanib (JAN/USAN/INN) <JP/US>
D10138 Regorafenib (USAN/INN)
D10137 Regorafenib hydrate (JAN) <JP/US>
D10062 Cabozantinib (USAN)
D10095 Cabozantinib s-malate (USAN) <JP/US>
D09919 Lenvatinib (USAN/INN) <US>
D09920 Lenvatinib mesylate (USAN) <JP>
D10481 Nintedanib (USAN/INN)
D10396 Nintedanib esylate (USAN) <JP/US>
D05029 Midostaurin (JAN/USAN/INN) <US>
D09371 Ramucirumab (USAN) <JP/US>
D05819 Semaxanib (USAN/INN)
D06285 Vatalanib (USAN/INN)
D06678 Motesanib (USAN)
D08503 Toceranib (USAN)
D08544 Toceranib phosphate (USAN)
D08878 Brivanib alaninate (JAN/USAN/INN)
D08907 Dovitinib lactate (USAN)
D08947 Motesanib diphosphate (USAN)
D09589 Brivanib (USAN)
D09618 Foretinib (USAN/INN)
D09635 Linifanib (USAN/INN)
D09945 Pegdinetanib (USAN/INN)
D10224 Golvatinib (USAN)
D10465 Golvatinib tartrate (USAN)
D10862 Altiratinib (USAN)
D11140 Sitravatinib (USAN/INN)
D11288 Rivoceranib (USAN/INN)
D11289 Rivoceranib mesylate (USAN)
D11541 Sitravatinib malate (USAN)
D11762 Lucitanib (USAN/INN)
D11772 Tesevatinib (USAN/INN)
D11773 Tesevatinib tosylate (USAN)
D11885 Surufatinib (USAN/INN)
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Monoclonal antibody
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VEGFR3 (FLT4) [HSA:2324] [KO:K05097]
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D03218 Axitinib (JAN/USAN) <JP/US>
D08881 Cediranib (USAN/INN)
D08883 Cediranib maleate (JAN/USAN)
D09683 Tivozanib (USAN/INN)
D10190 Tivozanib hydrochloride (USAN)
D08552 Sunitinib (INN)
D06402 Sunitinib malate (JAN/USAN) <JP/US>
D08524 Sorafenib (USAN/INN)
D06272 Sorafenib tosylate (USAN) <JP/US>
D05380 Pazopanib hydrochloride (JAN/USAN) <JP/US>
D10138 Regorafenib (USAN/INN)
D10137 Regorafenib hydrate (JAN) <JP/US>
D09919 Lenvatinib (USAN/INN) <US>
D09920 Lenvatinib mesylate (USAN) <JP>
D10481 Nintedanib (USAN/INN)
D10396 Nintedanib esylate (USAN) <JP/US>
D06285 Vatalanib (USAN/INN)
D06678 Motesanib (USAN)
D08907 Dovitinib lactate (USAN)
D08947 Motesanib diphosphate (USAN)
D09635 Linifanib (USAN/INN)
D11140 Sitravatinib (USAN/INN)
D11541 Sitravatinib malate (USAN)
D11713 Selpercatinib (JAN/USAN/INN) <US>
D11762 Lucitanib (USAN/INN)
D11772 Tesevatinib (USAN/INN)
D11773 Tesevatinib tosylate (USAN)
D11885 Surufatinib (USAN/INN)
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MET family
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TRK family
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EPH family
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AXL family
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ALK family
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TIE family
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RET family
|
RET [HSA:5979] [KO:K05126]
|
D08552 Sunitinib (INN)
D06402 Sunitinib malate (JAN/USAN) <JP/US>
D08524 Sorafenib (USAN/INN)
D06272 Sorafenib tosylate (USAN) <JP/US>
D06407 Vandetanib (JAN/USAN/INN) <JP/US>
D10138 Regorafenib (USAN/INN)
D10137 Regorafenib hydrate (JAN) <JP/US>
D09919 Lenvatinib (USAN/INN) <US>
D09920 Lenvatinib mesylate (USAN) <JP>
D06678 Motesanib (USAN)
D08947 Motesanib diphosphate (USAN)
|
|
RET* [HSA_VAR:5979v1] [HSA:5979] [KO:K05126]
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RET* [HSA_VAR:5979v1 5979v2] [HSA:5979] [KO:K05126]
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CCK family
|
Non-receptor tyrosine kinases
|
|
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Cytokines and receptors
|
|
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Cell surface molecules and ligands
|
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Transporters
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Enzymes
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Nucleic acids
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Not elsewhere classified
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Target-based Classification of Drugs