Target-based Classification of Drugs

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     Type
 G Protein-coupled receptors
   Rhodopsin family
     Acetylcholine (muscarinic)
     Adrenaline
     Dopamine
     Histamine
     Serotonin
       HTR1 [HSA:3350 3351 3352 3354 3355] [KO:K04153]
       HTR1A [HSA:3350] [KO:K04153]
       HTR1B [HSA:3351] [KO:K04153]
       HTR1D [HSA:3352] [KO:K04153]
       HTR1F [HSA:3355] [KO:K04153]
       HTR2 [HSA:3356 3357 3358] [KO:K04157]
         D07700  Cinitapride (INN)
         D07701  Cinitapride tartrate
         D07945  Fenfluramine (INN)
         D04148  Fenfluramine hydrochloride (USAN)
         D02577  Flibanserin (USAN/INN) <US>
         D02357  Methysergide (USAN/INN)
         D00681  Methysergide maleate (USP)
         D05523  Pizotyline (USAN)
         D08397  Pizotifen malate
         D07854  Dimetotiazine (INN)
         D01902  Fonazine mesylate (USAN) <JP>
         D00270  Chlorpromazine (USP/INN)
         D00789  Chlorpromazine hydrochloride (JP17/USP) <JP/US>
         D03274  Chlorpromazine hibenzate (JAN)
         D04034  Chlorpromazine phenolphthalinate (JAN) <JP>
         D09819  Chlorpromazine tannate (JAN)
         D01485  Propericiazine (JAN) <JP>
         D00454  Olanzapine (JAN/USP/INN) <JP/US>
         D06623  Olanzapine pamoate (USAN) <US>
         D02666  Iloperidone (USAN/INN) <US>
         D08297  Opipramol (INN)
         D01477  Opipramol hydrochloride (JAN/USAN)
         D08626  Trazodone (INN)
         D00820  Trazodone hydrochloride (JAN/USP) <JP/US>
         D00563  Mirtazapine (JAN/USP/INN) <JP/US>
         D11056  Mirtazapine hydrate (JAN)
         D02675  Ocaperidone (USAN)
         D02686  Setoperone (USAN/INN)
         D02688  Tiospirone hydrochloride (USAN)
         D02767  Adatanserin hydrochloride (USAN)
         D04320  Glemanserin (USAN/INN)
         D05015  Metrenperone (USAN/INN)
         D05395  Pelanserin hydrochloride (USAN)
         D05829  Sergolexole maleate (USAN)
         D06253  Tropanserin hydrochloride (USAN)
         D06343  Xylamidine tosylate (USAN)
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
       HTR2A [HSA:3356] [KO:K04157]
       HTR2C [HSA:3358] [KO:K04157]
       HTR4 [HSA:3360] [KO:K04160]
       HTR6 [HSA:3362] [KO:K04162]
       HTR7 [HSA:3363] [KO:K04163]
     Angiotensin
     Bradykinin
     Cholecystokinin
     Endothelin
     Follicle stimulating hormone
     Ghrelin
     Gonadotropin-releasing hormone
     Lutropin-choriogonadotropic hormone
     Melanocortin
     Motilin
     Neuropeptide Y
     Opioid
     Orexin
     Oxytocin
     Relaxin
     Somatostatin
     Tachykinin
     Thrombin
     Thyrotropin-releasing hormone
     Vasopressin
     Purine / pyrimidine
     Adenosine
     Cysteinyl leukotriene
     Free fatty acid
     Leukotriene
     Prostaglandin
     Prostacyclin
     Sphingolipid
     Thromboxane
     Cannabinoid
     Melatonin
     Platelet activating factor
   Secretin receptor family
   Metabotropic glutamate receptor family
   Frizzled / Smoothened family
 
 Ion channels
 
 Nuclear receptors
 
 Protein kinases
 
 Cytokines and receptors
 
 Cell surface molecules and ligands
 
 Transporters
   ABC transporters
   Solute carrier family
     SLC5
     SLC6
       SLC6A1 (GAT1) [HSA:6529] [KO:K05034]
       SLC6A2 (NAT1) [HSA:6530] [KO:K05035]
       SLC6A3 (DAT1) [HSA:6531] [KO:K05036]
       SLC6A4 (HTT) [HSA:6532] [KO:K05037]
         D05458  Phentermine (USAN/INN)
         D05459  Phentermine hydrochloride (USP) <US>
         D07945  Fenfluramine (INN)
         D04148  Fenfluramine hydrochloride (USAN)
         D07805  Dexfenfluramine (INN)
         D03713  Dexfenfluramine hydrochloride (USAN)
         D00367  Mazindol (JAN/USP/INN) <JP>
         D08513  Sibutramine (INN)
         D02571  Sibutramine hydrochloride (USP)
         D07875  Doxepin (INN)
         D00814  Doxepin hydrochloride (USP) <US>
         D03649  Dapoxetine hydrochloride (USAN)
         D00110  Cocaine (USP)
         D02182  Cocaine hydrochloride (JP17/USP) <JP/US>
         D07791  Desipramine (INN)
         D00812  Desipramine hydrochloride (JAN/USP) <US>
         D08070  Imipramine (INN)
         D00815  Imipramine hydrochloride (JP17/USP) <JP/US>
         D08071  Imipramine pamoate (USP) <US>
         D07727  Clomipramine (INN)
         D00811  Clomipramine hydrochloride (JP17/USP) <JP/US>
         D00394  Trimipramine (USAN/INN)
         D02408  Trimipramine maleate (JAN/USP) <JP/US>
         D08140  Lofepramine (INN)
         D01285  Lofepramine hydrochloride (JAN/USAN) <JP>
         D07448  Amitriptyline (INN)
         D00809  Amitriptyline hydrochloride (JP17/USP) <JP/US>
         D08288  Nortriptyline (INN)
         D00816  Nortriptyline hydrochloride (JP17/USP/INN) <JP/US>
         D08447  Protriptyline (INN)
         D00484  Protriptyline hydrochloride (USP) <US>
         D07872  Dosulepin (INN)
         D01546  Dothiepin hydrochloride (USAN) <JP>
         D00228  Amoxapine (JP17/USP/INN) <JP/US>
         D00326  Fluoxetine (USAN/INN)
         D00823  Fluoxetine hydrochloride (JAN/USP) <US>
         D07704  Citalopram (USP/INN)
         D00822  Citalopram hydrobromide (USP) <US>
         D07705  Citalopram hydrochloride
         D02362  Paroxetine (USP/INN)
         D02260  Paroxetine hydrochloride hemihydrate (USP) <JP/US>
         D05374  Paroxetine hydrochloride (USP) <US>
         D05375  Paroxetine mesylate (USAN) <US>
         D02360  Sertraline (INN)
         D00825  Sertraline hydrochloride (JAN/USP) <JP/US>
         D02787  Alaproclate (USAN/INN)
         D07984  Fluvoxamine (INN)
         D00824  Fluvoxamine maleate (JP17/USP) <JP/US>
         D07913  Escitalopram (INN)
         D02567  Escitalopram oxalate (JAN/USP) <JP/US>
         D08626  Trazodone (INN)
         D00820  Trazodone hydrochloride (JAN/USP) <JP/US>
         D08670  Venlafaxine (INN)
         D00821  Venlafaxine hydrochloride (JAN/USP) <JP/US>
         D08222  Milnacipran (INN)
         D01107  Milnacipran hydrochloride (JAN/USAN) <JP/US>
         D07880  Duloxetine (INN)
         D01179  Duloxetine hydrochloride (JAN/USP) <JP/US>
         D07793  Desvenlafaxine (INN) <US>
         D02570  Desvenlafaxine succinate (USAN) <US>
         D09698  Vilazodone (USAN/INN)
         D09699  Vilazodone hydrochloride (USAN) <US>
         D10184  Vortioxetine (USAN)
         D10185  Vortioxetine hydrobromide (JAN/USAN) <JP/US>
         D08187  Metamfetamine (INN)
         D02242  Methamphetamine hydrochloride (JP17/USP) <JP/US>
         D07806  Dexmethylphenidate (INN)
         D03721  Dexmethylphenidate hydrochloride (USAN) <US>
         D02170  Indeloxazine hydrochloride (JAN/USAN)
         D03491  Cidoxepin hydrochloride (USAN)
         D04788  Lubazodone hydrochloride (USAN)
         D05491  Pirandamine hydrochloride (USAN)
         D07334  Imipraminoxide (INN)
         D07449  Amitriptylinoxide (INN)
         D08072  Imipraminoxide hydrochloride
         D08077  Indeloxazine (INN)
         D10072  Levomilnacipran (USAN/INN)
         D10088  Amitifadine (USAN)
         D10089  Amitifadine hydrochloride (USAN)
         D10133  Levomilnacipran hydrochloride (USAN) <US>
         D10443  Liafensine (USAN)
         D10697  Centanafadine (USAN)
         D10698  Centanafadine hydrochloride (USAN)
         D11169  Lumateperone (USAN/INN)
         D11170  Lumateperone tosylate (USAN)
         D11172  Midomafetamine (USAN/INN)
         D11619  Desvenlafaxine succinate anhydrous
         D11688  Ampreloxetin (USAN/INN)
         D11689  Ampreloxetin hydrochloride (USAN)
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
       SLC6A9 (GLYT1) [HSA:6536] [KO:K05038]
     SLC9
     SLC10
     SLC12
     SLC18
     SLC22
     SLC29
     SLC34
   Major facilitator superfamily
   Other transporters
 
 Enzymes
 
 Nucleic acids
 
 Not elsewhere classified

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Last updated: February 15, 2020

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