Target-based Classification of Drugs

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     Type
 G Protein-coupled receptors
 
 Ion channels
 
 Nuclear receptors
 
 Protein kinases
   Serine/threonine kinases
   Receptor serine/threonine kinases (RSTK)
   Receptor tyrosine kinases (RTK)
     EGFR family
       EGFR [HSA:1956] [KO:K04361]
       EGFR* [HSA_VAR:1956v2] [HSA:1956] [KO:K04361]
       EGFR* [HSA_VAR:1956v3] [HSA:1956] [KO:K04361]
       ERBB2 (HER2, CD340) [HSA:2064] [KO:K05083]
       ERBB2* (HER2, CD340) [HSA_VAR:2064v1] [HSA:2064] [KO:K05083]
       ERBB2* (HER2, CD340) [HSA_VAR:2064v1 2064v3] [HSA:2064] [KO:K05083]
         D05446  Pertuzumab (USAN/INN) <JP/US>
         D09980  Trastuzumab emtansine (USAN/INN) <JP/US>
         D10898  Neratinib maleate <US>
Monoclonal antibody
Antibody-drug conjugate
 
       ERBB3 (HER3) [HSA:2065] [KO:K05084]
       ERBB4 (HER4) [HSA:2066] [KO:K05085]
     INSR family
     PDGFR family
     FGFR family
     VEGFR family
     MET family
     TRK family
     EPH family
     AXL family
     ALK family
     TIE family
     RET family
     CCK family
   Non-receptor tyrosine kinases
 
 Cytokines and receptors
 
 Cell surface molecules and ligands
 
 Transporters
 
 Enzymes
 
 Nucleic acids
 
 Not elsewhere classified
   Signaling molecules
   Cellular process
     Cell cycle
     Apoptosis
     Membrane trafficking
     Cytoskeleton
       MYH [HSA:4624 4625] [KO:K17751]
       TNNC2 [HSA:7125] [KO:K12042]
       TNNI2 [HSA:7136] [KO:K12043]
       TNNT3 [HSA:7140] [KO:K12046]
       DMD [HSA:1756] [KO:K10366]
       DMD* [HSA_VAR:1756v1] [HSA:1756] [KO:K10366]
       TUBB [HSA:10381 10382 10383 203068 347688 347733 7280 81027 84617] [KO:K07375]
         D05529  Podofilox (USAN) <US>
         D08675  Vinblastine (INN)
         D01068  Vinblastine sulfate (JP17/USP) <JP/US>
         D08679  Vincristine (INN)
         D02197  Vincristine sulfate (JP17/USP) <JP/US>
         D06304  Vindesine (USAN/INN)
         D01769  Vindesine sulfate (JAN/USAN) <JP>
         D08680  Vinorelbine (INN)
         D01935  Vinorelbine tartrate (USP) <JP/US>
         D09032  Vinflunine ditartrate (USAN)
         D00491  Paclitaxel (JAN/USP/INN) <JP/US>
         D07866  Docetaxel (JAN/INN) <JP/US>
         D02165  Docetaxel (USP) <JP/US>
         D05333  Paclitaxel poliglumex (USAN/INN)
         D09755  Cabazitaxel (USAN/INN)
         D10452  Cabazitaxel acetonate (JAN) <JP/US>
         D04645  Ixabepilone (JAN/USAN/INN) <US>
         D09587  Brentuximab vedotin (USAN) <JP/US>
         D09980  Trastuzumab emtansine (USAN/INN) <JP/US>
         D04066  Estramustine (USAN/INN)
         D02398  Estramustine phosphate sodium (USAN)
         D06397  Estramustine phosphate sodium hydrate (JAN) <JP/US>
         D08914  Eribulin mesylate (USAN) <JP/US>
         D00570  Colchicine (JP17/USP) <JP/US>
         D01919  Soblidotin (JAN/INN)
         D03059  Batabulin sodium (USAN)
         D04864  Maytansine (USAN)
         D05062  Mivobulin isethionate (USAN)
         D06001  Taltobulin (USAN/INN)
         D06009  Tasidotin hydrochloride (USAN)
         D06305  Vinepidine sulfate (USAN)
         D06306  Vinglycinate sulfate (USAN)
         D06307  Vinleurosine sulfate (USAN)
         D06308  Vinrosidine sulfate (USAN)
         D06309  Vinzolidine sulfate (USAN)
         D06560  Batabulin (USAN/INN)
         D06576  Cevipabulin fumarate (USAN)
         D08889  Cevipabulin succinate (USAN)
         D09912  Glembatumumab vedotin (USAN)
         D10013  Indibulin (USAN/INN)
         D10029  Verubulin (USAN/INN)
         D10030  Verubulin hydrochloride (USAN)
         D10073  Lexibulin (USAN)
         D11232  Denintuzumab mafodotin (USAN/INN)
         D11238  Lifastuzumab vedotin (USAN/INN)
         D11494  Lisavanbulin (USAN/INN)
         D11525  Enfortumab vedotin (USAN) <US>
         D11681  Avanbulin (USAN/INN)
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Antibody-drug conjugate
Antibody-drug conjugate
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Antibody-drug conjugate
 
 
 
 
Monoclonal antibody
Monoclonal antibody
 
Antibody-drug conjugate
 
       KIF11 [HSA:3832] [KO:K10398]
       MAPT (TAU) [HSA:4137] [KO:K04380]
     Ubiquitin system
   Organismal systems
   Unclassified

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Last updated: October 13, 2020

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