 G Protein-coupled receptors
|
Rhodopsin family
|
 Acetylcholine (muscarinic)
|
Adrenaline
|
Dopamine
|
Histamine
|
Serotonin
|
HTR1 [HSA:3350 3351 3352 3354 3355] [KO:K04153]
|
HTR1A [HSA:3350] [KO:K04153]
|
 D07906 Ergotamine (INN)
D02577 Flibanserin (USAN/INN) <US>
D00679 Ergotamine tartrate (JP18/USP) <US>
D02357 Methysergide (USAN/INN)
D00681 Methysergide maleate (USP)
D08385 Pipotiazine (INN)
D02680 Pipotiazine palmitate (USAN)
D02995 Asenapine maleate (JAN/USAN) <JP/US>
D01164 Aripiprazole (JAN/USP/INN) <JP/US>
D10355 Aripiprazole cavoxil (USAN)
D10364 Aripiprazole lauroxil (USAN) <US>
D10516 Aripiprazole hydrate (JAN) <JP/US>
D09997 Cariprazine (USAN/INN)
D09876 Cariprazine hydrochloride (JAN/USAN) <US>
D10309 Brexpiprazole (JAN/USAN/INN) <JP/US>
D07593 Buspirone (INN)
D00702 Buspirone hydrochloride (USP) <US>
D04314 Gepirone hydrochloride (USAN) <US>
D09698 Vilazodone (USAN/INN)
D09699 Vilazodone hydrochloride (USAN) <US>
D10184 Vortioxetine (USAN)
D10185 Vortioxetine hydrobromide (JAN/USAN) <JP/US>
D12544 Vortioxetine hemihydrobromide (USAN)
D06327 Xaliproden (USAN)
D01537 Xaliproden hydrochloride (JAN)
D01992 Tandospirone citrate (JAN/USAN) <JP>
D02568 Flesinoxan (INN)
D02569 Sunepitron hydrochloride (USAN)
D02576 Eptapirone (INN)
D02688 Tiospirone hydrochloride (USAN)
D02767 Adatanserin hydrochloride (USAN)
D03121 Binospirone mesylate (USAN)
D04611 Ipsapirone hydrochloride (USAN)
D04683 Lecozotan hydrochloride (USAN)
D05804 Sarizotan hydrochloride (USAN)
D06354 Zalospirone hydrochloride (USAN)
D06566 Bifeprunox (USAN/INN)
D06567 Bifeprunox mesylate (USAN)
D08561 Tandospirone (INN)
D09358 Naluzotan (USAN/INN)
D09359 Naluzotan hydrochloride (USAN)
D09366 Pardoprunox hydrochloride (USAN)
D09397 Pardoprunox (USAN/INN)
D12474 Ulotaront (USAN/INN)
D12475 Ulotaront hydrochloride (JAN/USAN)
|
HTR1B [HSA:3351] [KO:K04153]
|
HTR1D [HSA:3352] [KO:K04153]
|
HTR1F [HSA:3355] [KO:K04153]
|
HTR2 [HSA:3356 3357 3358] [KO:K04157]
|
HTR2A [HSA:3356] [KO:K04157]
|
HTR2C [HSA:3358] [KO:K04157]
|
HTR4 [HSA:3360] [KO:K04160]
|
HTR6 [HSA:3362] [KO:K04162]
|
HTR7 [HSA:3363] [KO:K04163]
|
Trace amine
|
Angiotensin
|
Bradykinin
|
Cholecystokinin
|
Endothelin
|
Follicle stimulating hormone
|
Ghrelin
|
Gonadotropin-releasing hormone
|
Lutropin-choriogonadotropic hormone
|
Melanocortin
|
Motilin
|
Neuropeptide Y
|
Opioid
|
Orexin
|
Oxytocin
|
Relaxin
|
Somatostatin
|
Tachykinin
|
Thrombin
|
Thyrotropin-releasing hormone
|
Vasopressin
|
Purine / pyrimidine
|
Adenosine
|
Cysteinyl leukotriene
|
Free fatty acid
|
Leukotriene
|
Lysophosphatidic acid
|
Prostaglandin
|
Prostacyclin
|
Sphingolipid
|
Thromboxane
|
Cannabinoid
|
Melatonin
|
Platelet activating factor
|
R-spondin
|
Secretin receptor family
|
Metabotropic glutamate receptor family
|
Frizzled / Smoothened family
|
Others
|
|
Ion channels
|
Ligand-gated ion channels
|
Acetylcholine (nicotinic)
|
Serotonin
|
HTR3 [HSA:3359 9177 170572 200909 285242] [KO:K04819]
|
D07129 Alosetron (INN)
D02829 Alosetron hydrochloride (USAN) <US>
D03495 Cilansetron (USAN/INN)
D03496 Cilansetron hydrochloride (USAN)
D00456 Ondansetron (JAN/USP/INN) <US>
D00678 Ondansetron hydrochloride hydrate (JAN/USP) <JP/US>
D02130 Tropisetron (INN)
D02041 Tropisetron hydrochloride (JAN)
D07867 Dolasetron (INN)
D00725 Dolasetron mesylate (USP) <US>
D07175 Palonosetron (INN)
D05343 Palonosetron hydrochloride (JAN/USP) <JP/US>
D00283 Clozapine (JAN/USP/INN) <JP/US>
D08216 Mianserin (INN)
D01358 Mianserin hydrochloride (JAN/USAN) <JP>
D00563 Mirtazapine (JAN/USP/INN) <JP/US>
D11056 Mirtazapine hydrate (JAN)
D10184 Vortioxetine (USAN)
D10185 Vortioxetine hydrobromide (JAN/USAN) <JP/US>
D12544 Vortioxetine hemihydrobromide (USAN)
D01613 Azasetron hydrochloride (JAN)
D01838 Fabesetron hydrochloride (JAN)
D02016 Ramosetron hydrochloride (JAN) <JP>
D02632 Indisetron hydrochloride (JAN)
D03060 Batanopride hydrochloride (USAN)
D03073 Bemesetron (USAN/INN)
D03662 Dazopride fumarate (USAN)
D04294 Galdansetron hydrochloride (USAN)
D04642 Itasetron (USAN/INN)
D04821 Lurosetron mesylate (USAN)
D05050 Mirisetron maleate (USAN)
D05348 Pancopride (USAN/INN)
D05685 Quipazine maleate (USAN)
D06253 Tropanserin hydrochloride (USAN)
D06353 Zacopride hydrochloride (USAN)
D06358 Zatosetron maleate (USAN)
D06396 Renzapride (INN)
D07481 Azasetron (INN)
D08466 Ramosetron (INN)
D09749 Itasetron hydrochloride hydrate (JAN)
D10170 Tedatioxetine (USAN)
D10171 Tedatioxetine hydrobromide (USAN)
|
HTR3A [HSA:3359] [KO:K04819]
|
HTR3B [HSA:9177] [KO:K04819]
|
GABA (ionotropic)
|
Glycine
|
Glutamate (ionotropic), non-NMDA
|
Glutamate (ionotropic), NMDA
|
Epithelial sodium channel (SCNN)
|
ATP-gated cation channel (P2X)
|
Voltage-gated ion channels
|
Other ion channels
|
|
Nuclear receptors
|
|
Protein kinases
|
|
Cytokines and receptors
|
|
Cell surface molecules and ligands
|
|
Transporters
|
ABC transporters
|
Solute carrier family
|
SLC5
|
SLC6
|
SLC6A1 (GAT1) [HSA:6529] [KO:K05034]
|
SLC6A2 (NAT1) [HSA:6530] [KO:K05035]
|
SLC6A3 (DAT1) [HSA:6531] [KO:K05036]
|
SLC6A4 (HTT) [HSA:6532] [KO:K05037]
|
D05458 Phentermine (USAN/INN)
D05459 Phentermine hydrochloride (USP) <US>
D07945 Fenfluramine (INN)
D04148 Fenfluramine hydrochloride (JAN/USAN) <JP/US>
D07805 Dexfenfluramine (INN)
D03713 Dexfenfluramine hydrochloride (USAN)
D00367 Mazindol (JAN/USP/INN) <JP>
D08513 Sibutramine (INN)
D02571 Sibutramine hydrochloride (USP)
D07875 Doxepin (INN)
D00814 Doxepin hydrochloride (USP) <US>
D03649 Dapoxetine hydrochloride (USAN)
D00110 Cocaine (USP)
D02182 Cocaine hydrochloride (JP18/USP) <US>
D07791 Desipramine (INN)
D00812 Desipramine hydrochloride (JAN/USP) <US>
D08070 Imipramine (INN)
D00815 Imipramine hydrochloride (JP18/USP) <JP/US>
D08071 Imipramine pamoate (USP) <US>
D07727 Clomipramine (INN)
D00811 Clomipramine hydrochloride (JP18/USP) <JP/US>
D00394 Trimipramine (USAN/INN)
D02408 Trimipramine maleate (JAN/USP) <JP/US>
D08140 Lofepramine (INN)
D01285 Lofepramine hydrochloride (JAN/USAN) <JP>
D07448 Amitriptyline (INN)
D00809 Amitriptyline hydrochloride (JP18/USP) <JP/US>
D08288 Nortriptyline (INN)
D00816 Nortriptyline hydrochloride (JP18/USP/INN) <JP/US>
D08447 Protriptyline (INN)
D00484 Protriptyline hydrochloride (USP) <US>
D07872 Dosulepin (INN)
D01546 Dothiepin hydrochloride (USAN) <JP>
D00228 Amoxapine (JP18/USP/INN) <JP/US>
D00326 Fluoxetine (USAN/INN)
D00823 Fluoxetine hydrochloride (JAN/USP) <US>
D07704 Citalopram (USP/INN)
D00822 Citalopram hydrobromide (USP) <US>
D07705 Citalopram hydrochloride
D02362 Paroxetine (USP/INN)
D02260 Paroxetine hydrochloride hemihydrate (USP) <JP/US>
D05374 Paroxetine hydrochloride (USP) <US>
D05375 Paroxetine mesylate (USAN) <US>
D02360 Sertraline (INN)
D00825 Sertraline hydrochloride (JAN/USP) <JP/US>
D02787 Alaproclate (USAN/INN)
D07984 Fluvoxamine (INN)
D00824 Fluvoxamine maleate (JP18/USP) <JP/US>
D07913 Escitalopram (INN)
D02567 Escitalopram oxalate (JAN/USP) <JP/US>
D08626 Trazodone (INN)
D00820 Trazodone hydrochloride (JAN/USP) <JP/US>
D08670 Venlafaxine (INN)
D00821 Venlafaxine hydrochloride (JAN/USP) <JP/US>
D12403 Venlafaxine besylate monohydrate <US>
D08222 Milnacipran (INN)
D01107 Milnacipran hydrochloride (JAN/USAN) <JP/US>
D07880 Duloxetine (INN)
D01179 Duloxetine hydrochloride (JAN/USP) <JP/US>
D07793 Desvenlafaxine (INN) <US>
D02570 Desvenlafaxine succinate (USAN) <US>
D11619 Desvenlafaxine succinate anhydrous <US>
D09698 Vilazodone (USAN/INN)
D09699 Vilazodone hydrochloride (USAN) <US>
D10184 Vortioxetine (USAN)
D10185 Vortioxetine hydrobromide (JAN/USAN) <JP/US>
D12544 Vortioxetine hemihydrobromide (USAN)
D10072 Levomilnacipran (USAN/INN)
D10133 Levomilnacipran hydrochloride (USAN) <US>
D08187 Metamfetamine (INN)
D02242 Methamphetamine hydrochloride (JP18/USP) <JP/US>
D07806 Dexmethylphenidate (INN)
D03721 Dexmethylphenidate hydrochloride (USAN) <US>
D02170 Indeloxazine hydrochloride (JAN/USAN)
D03491 Cidoxepin hydrochloride (USAN)
D04788 Lubazodone hydrochloride (USAN)
D05491 Pirandamine hydrochloride (USAN)
D07334 Imipraminoxide (INN)
D07449 Amitriptylinoxide (INN)
D08072 Imipraminoxide hydrochloride
D08077 Indeloxazine (INN)
D10088 Amitifadine (USAN)
D10089 Amitifadine hydrochloride (USAN)
D10443 Liafensine (USAN/INN)
D10697 Centanafadine (USAN/INN)
D10698 Centanafadine hydrochloride (USAN)
D11172 Midomafetamine (USAN/INN)
D11688 Ampreloxetine (USAN/INN)
D11689 Ampreloxetine hydrochloride (USAN)
D11940 Toludesvenlafaxine (USAN/INN)
D11941 Toludesvenlafaxine hydrochloride (USAN)
D12715 Tenamfetamine (INN)
|
SLC6A8 [HSA:6535] [KO:K05041]
|
SLC6A9 (GLYT1) [HSA:6536] [KO:K05038]
|
SLC7
|
SLC9
|
SLC10
|
SLC12
|
SLC18
|
SLC22
|
SLC29
|
SLC34
|
SLC40
|
Major facilitator superfamily
|
Other transporters
|
|
Enzymes
|
|
Nucleic acids
|
|
Not elsewhere classified
|
Target-based Classification of Drugs