Target-based Classification of Drugs

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 G Protein-coupled receptors
 Ion channels
 Nuclear receptors
 Protein kinases
 Cytokines and receptors
 Cell surface molecules and ligands
   Oxidoreductases (EC1)
   Transferases (EC2)
   Hydrolases (EC3)
     Carboxylic-ester hydrolases [EC:3.1.1.-]
     Phosphatases [EC:3.1.3.-]
     Phosphodiesterases [EC:3.1.4.-]
       SMPD1* [HSA_VAR:6609v1] [HSA:6609] [KO:K12350]
         D10820  Olipudase alfa (INN)
Enzyme replacement therapy product
       PDE [HSA:10846 27115 50940 5136 5137 5138 5139 5140 5141 5142 5143 5144 5150 5151 5153 8622] [KO:K18438 K18436 K13298 K13755 K18283 K19021 K13296 K13293 K18437]
       PDE [HSA:5153 5138 5139 5140 5141 5142 5143 5144 8654] [KO:K13755 K18283 K19021 K13296 K13293 K13762]
       PDE1 [HSA:5136 5153 5137] [KO:K13755]
       PDE2A [HSA:5138] [KO:K18283]
       PDE3 [HSA:5139 5140] [KO:K19021 K13296]
       PDE4 [HSA:5141 5142 5143 5144] [KO:K13293]
       PDE4A [HSA:5141] [KO:K13293]
       PDE5 [HSA:8654] [KO:K13762]
       PDE10A [HSA:10846] [KO:K18438]
       ENPP2 (ATX) [HSA:5168] [KO:K01122]
     Sulfatases [EC:3.1.6.-]
     Glycosidases [EC:3.2.1.-]
     ADP-ribosyl cyclase [EC:]
     Aminopeptidases [EC:3.4.11.-]
     Dipeptidases [EC:3.4.13.-]
     Peptidyl-peptidases [EC:3.4.14.-]
     Peptidyl-dipeptidases [EC:3.4.15.-]
     Metallocarboxypeptidases [EC:3.4.17.-]
     Serine peptidases [EC:3.4.21.-]
     Cysteine peptidases [EC:3.4.22.-]
     Aspartic peptidases [EC:3.4.23.-]
     Metallo peptidases [EC:3.4.24.- 3.4.17.-]
     Threonine peptidases [EC:3.4.25.-]
     Glutaminase [EC:]
     Histone deacetylase [EC:]
     Arginase [EC:]
     Adenosine deaminase [EC:]
     ATPase [EC:3.6.3.-]
   Lyases (EC4)
   Isomerases (EC5)
   Ligases (EC6)
 Nucleic acids
 Not elsewhere classified

Last updated: February 27, 2021

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