Target-based Classification of Drugs

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     Type
 G Protein-coupled receptors
 
 Ion channels
 
 Nuclear receptors
 
 Protein kinases
   Serine/threonine kinases
   Receptor serine/threonine kinases (RSTK)
   Receptor tyrosine kinases (RTK)
     EGFR family
       EGFR [HSA:1956] [KO:K04361]
       EGFR* [HSA_VAR:1956v2] [HSA:1956] [KO:K04361]
       EGFR* [HSA_VAR:1956v3] [HSA:1956] [KO:K04361]
       ERBB2 (HER2, CD340) [HSA:2064] [KO:K05083]
         D08108  Lapatinib (INN)
         D09724  Afatinib (USAN/INN)
         D09733  Afatinib dimaleate (USAN) <JP/US>
         D08950  Neratinib (USAN/INN)
         D09883  Dacomitinib (INN)
         D10514  Dacomitinib (USAN) <JP/US>
         D03350  Canertinib dihydrochloride (USAN)
         D04025  Mubritinib (USAN/INN)
         D06610  Lapuleucel-T (USAN)
         D09689  Varlitinib (USAN/INN)
         D09690  Varlitinib tosylate (USAN)
         D10344  Nelipepimut-S (USAN)
         D10446  Margetuximab (USAN)
         D11141  Tucatinib (USAN/INN) <US>
         D11375  Trastuzumab duocarmazine (USAN/INN)
         D11772  Tesevatinib (USAN/INN)
         D11773  Tesevatinib tosylate (USAN)
 
 
 
 
 
 
 
 
 
 
 
 
Monoclonal antibody
 
Antibody-drug conjugate
 
 
       ERBB2* (HER2, CD340) [HSA_VAR:2064v1] [HSA:2064] [KO:K05083]
       ERBB2* (HER2, CD340) [HSA_VAR:2064v1 2064v3] [HSA:2064] [KO:K05083]
       ERBB3 (HER3) [HSA:2065] [KO:K05084]
         D03350  Canertinib dihydrochloride (USAN)
         D10943  Istiratumab (USAN)
         D11141  Tucatinib (USAN/INN) <US>
         D11239  Lumretuzumab (USAN/INN)
         D11750  Duligotuzumab (USAN)
         D11777  Seribantumab (USAN/INN)
 
Monoclonal antibody
 
Monoclonal antibody
Monoclonal antibody
Monoclonal antibody
       ERBB4 (HER4) [HSA:2066] [KO:K05085]
     INSR family
     PDGFR family
     FGFR family
     VEGFR family
     MET family
     TRK family
     EPH family
     AXL family
     ALK family
     TIE family
     RET family
     CCK family
   Non-receptor tyrosine kinases
 
 Cytokines and receptors
 
 Cell surface molecules and ligands
 
 Transporters
 
 Enzymes
 
 Nucleic acids
 
 Not elsewhere classified

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Last updated: July 8, 2020

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