Target-based Classification of Drugs

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 G Protein-coupled receptors
 
 Ion channels
 
 Nuclear receptors
 
 Protein kinases
 
 Cytokines and receptors
 
 Cell surface molecules and ligands
 
 Transporters
   ABC transporters
   Solute carrier family
     SLC5
     SLC6
       SLC6A1 (GAT1) [HSA:6529] [KO:K05034]
       SLC6A2 (NAT1) [HSA:6530] [KO:K05035]
         D05458  Phentermine (USAN/INN)
         D05459  Phentermine hydrochloride (USP) <US>
         D07444  Amfepramone (INN)
         D03801  Diethylpropion hydrochloride (USP) <US>
         D00367  Mazindol (JAN/USP/INN) <JP>
         D08513  Sibutramine (INN)
         D02571  Sibutramine hydrochloride (USP)
         D01304  Amezinium metilsulfate (JAN) <JP>
         D08030  Guanethidine (INN)
         D02237  Guanethidine sulfate (USAN)
         D04382  Guanethidine monosulfate (USP)
         D07875  Doxepin (INN)
         D00814  Doxepin hydrochloride (USP) <US>
         D00110  Cocaine (USP)
         D02182  Cocaine hydrochloride (JP17/USP) <JP/US>
         D06007  Tapentadol (USAN/INN)
         D10199  Tapentadol hydrochloride (JAN) <JP/US>
         D07791  Desipramine (INN)
         D00812  Desipramine hydrochloride (JAN/USP) <US>
         D08070  Imipramine (INN)
         D00815  Imipramine hydrochloride (JP17/USP) <JP/US>
         D08071  Imipramine pamoate (USP) <US>
         D07727  Clomipramine (INN)
         D00811  Clomipramine hydrochloride (JP17/USP) <JP/US>
         D00394  Trimipramine (USAN/INN)
         D02408  Trimipramine maleate (JAN/USP) <JP/US>
         D08140  Lofepramine (INN)
         D01285  Lofepramine hydrochloride (JAN/USAN) <JP>
         D07448  Amitriptyline (INN)
         D00809  Amitriptyline hydrochloride (JP17/USP) <JP/US>
         D08288  Nortriptyline (INN)
         D00816  Nortriptyline hydrochloride (JP17/USP/INN) <JP/US>
         D08447  Protriptyline (INN)
         D00484  Protriptyline hydrochloride (USP) <US>
         D07872  Dosulepin (INN)
         D01546  Dothiepin hydrochloride (USAN) <JP>
         D00228  Amoxapine (JP17/USP/INN) <JP/US>
         D02566  Maprotiline (USAN)
         D00818  Maprotiline hydrochloride (JP17/USP) <JP/US>
         D05200  Nomifensine maleate (USAN)
         D08673  Viloxazine (INN)
         D02572  Viloxazine hydrochloride (USAN)
         D07591  Bupropion (INN)
         D00817  Bupropion hydrochloride (JAN/USP) <US>
         D07938  Bupropion hydrobromide (USAN) <US>
         D08670  Venlafaxine (INN)
         D00821  Venlafaxine hydrochloride (JAN/USP) <JP/US>
         D08222  Milnacipran (INN)
         D01107  Milnacipran hydrochloride (JAN/USAN) <JP/US>
         D08472  Reboxetine (INN)
         D02573  Reboxetine mesylate (USAN)
         D07880  Duloxetine (INN)
         D01179  Duloxetine hydrochloride (JAN/USP) <JP/US>
         D07793  Desvenlafaxine (INN) <US>
         D02570  Desvenlafaxine succinate (USAN) <US>
         D07445  Amfetamine (INN) <US>
         D02074  Amphetamine sulfate (USP) <US>
         D03740  Dextroamphetamine (USAN)
         D02078  Dextroamphetamine sulfate (USP) <US>
         D08187  Metamfetamine (INN)
         D02242  Methamphetamine hydrochloride (JP17/USP) <JP/US>
         D04999  Methylphenidate (USAN/INN) <US>
         D01296  Methylphenidate hydrochloride (JAN/USP) <JP/US>
         D07473  Atomoxetine (USP/INN)
         D02574  Atomoxetine hydrochloride (JAN/USP) <JP/US>
         D07806  Dexmethylphenidate (INN)
         D03721  Dexmethylphenidate hydrochloride (USAN) <US>
         D08130  Lisdexamfetamine (INN)
         D04747  Lisdexamfetamine dimesylate (USAN) <JP/US>
         D11315  Solriamfetol (USAN)
         D11328  Solriamfetol hydrochloride (USAN) <US>
         D02080  Phendimetrazine tartrate (USP) <US>
         D02170  Indeloxazine hydrochloride (JAN/USAN)
         D02704  Tampramine fumarate (USAN)
         D03491  Cidoxepin hydrochloride (USAN)
         D04473  Hydroxyamphetamine hydrobromide (USP)
         D04781  Lortalamine (USAN/INN)
         D05119  Napamezole hydrochloride (USAN)
         D05120  Napitane mesylate (USAN)
         D05173  Nisoxetine (USAN/INN)
         D05284  Oxaprotiline hydrochloride (USAN)
         D05454  Phenmetrazine hydrochloride (USP)
         D05663  Pyrovalerone hydrochloride (USAN)
         D05692  Radafaxine hydrochloride (USAN)
         D05997  Talopram hydrochloride (USAN)
         D06004  Tandamine hydrochloride (USAN)
         D07334  Imipraminoxide (INN)
         D07449  Amitriptylinoxide (INN)
         D07514  Benzfetamine (INN)
         D07515  Benzfetamine hydrochloride <US>
         D08072  Imipraminoxide hydrochloride
         D08077  Indeloxazine (INN)
         D08347  Phendimetrazine (INN)
         D08348  Phendimetrazine hydrochloride
         D09340  Esreboxetine (USAN/INN)
         D09341  Esreboxetine succinate (USAN)
         D09890  Edivoxetine (USAN/INN)
         D09891  Edivoxetine hydrochloride (USAN)
         D10072  Levomilnacipran (USAN/INN)
         D10088  Amitifadine (USAN)
         D10089  Amitifadine hydrochloride (USAN)
         D10133  Levomilnacipran hydrochloride (USAN) <US>
         D10443  Liafensine (USAN)
         D10697  Centanafadine (USAN)
         D10698  Centanafadine hydrochloride (USAN)
         D10700  Dasotraline (USAN/INN)
         D10870  Dasotraline hydrochloride (USAN)
         D11172  Midomafetamine (USAN/INN)
         D11619  Desvenlafaxine succinate anhydrous <US>
         D11622  Amphetamine aspartate monohydrate
         D11623  Dextroamphetamine saccharate
         D11688  Ampreloxetine (USAN/INN)
         D11689  Ampreloxetine hydrochloride (USAN)
         D11940  Toludesvenlafaxine (USAN/INN)
         D11941  Toludesvenlafaxine hydrochloride (USAN)
       SLC6A3 (DAT1) [HSA:6531] [KO:K05036]
         D05458  Phentermine (USAN/INN)
         D05459  Phentermine hydrochloride (USP) <US>
         D07444  Amfepramone (INN)
         D03801  Diethylpropion hydrochloride (USP) <US>
         D00367  Mazindol (JAN/USP/INN) <JP>
         D08513  Sibutramine (INN)
         D02571  Sibutramine hydrochloride (USP)
         D00110  Cocaine (USP)
         D02182  Cocaine hydrochloride (JP17/USP) <JP/US>
         D07591  Bupropion (INN)
         D00817  Bupropion hydrochloride (JAN/USP) <US>
         D07938  Bupropion hydrobromide (USAN) <US>
         D07445  Amfetamine (INN) <US>
         D02074  Amphetamine sulfate (USP) <US>
         D03740  Dextroamphetamine (USAN)
         D02078  Dextroamphetamine sulfate (USP) <US>
         D08187  Metamfetamine (INN)
         D02242  Methamphetamine hydrochloride (JP17/USP) <JP/US>
         D04999  Methylphenidate (USAN/INN) <US>
         D01296  Methylphenidate hydrochloride (JAN/USP) <JP/US>
         D07806  Dexmethylphenidate (INN)
         D03721  Dexmethylphenidate hydrochloride (USAN) <US>
         D08130  Lisdexamfetamine (INN)
         D04747  Lisdexamfetamine dimesylate (USAN) <JP/US>
         D03215  Armodafinil (USAN/INN) <US>
         D11315  Solriamfetol (USAN)
         D11328  Solriamfetol hydrochloride (USAN) <US>
         D10014  Ioflupane I 123 (USAN) <JP/US>
         D02897  Amfonelic acid (USAN)
         D03153  Brasofensine maleate (USAN)
         D05119  Napamezole hydrochloride (USAN)
         D05454  Phenmetrazine hydrochloride (USP)
         D05663  Pyrovalerone hydrochloride (USAN)
         D05692  Radafaxine hydrochloride (USAN)
         D07514  Benzfetamine (INN)
         D07515  Benzfetamine hydrochloride <US>
         D10088  Amitifadine (USAN)
         D10089  Amitifadine hydrochloride (USAN)
         D10697  Centanafadine (USAN)
         D10698  Centanafadine hydrochloride (USAN)
         D10700  Dasotraline (USAN/INN)
         D10870  Dasotraline hydrochloride (USAN)
         D11172  Midomafetamine (USAN/INN)
         D11622  Amphetamine aspartate monohydrate
         D11623  Dextroamphetamine saccharate
       SLC6A4 (HTT) [HSA:6532] [KO:K05037]
       SLC6A9 (GLYT1) [HSA:6536] [KO:K05038]
     SLC9
     SLC10
     SLC12
     SLC18
     SLC22
     SLC29
     SLC34
   Major facilitator superfamily
   Other transporters
 
 Enzymes
 
 Nucleic acids
 
 Not elsewhere classified

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Last updated: March 6, 2021

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