Peptidases and Inhibitors - Canis lupus familiaris (dog)

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     KO
 Aspartic peptidases
 
 Cysteine peptidases
 
 Glutamic peptidases
 
 Metallo peptidases
 
 Asparagine peptide lyases
 
 Mixed peptidases
 
 Serine peptidases
   Family S1: chymotrypsin family
     479649 chymostrypsinogen B1-like precursor
     479650 CTRB2; chymotrypsinogen 2
     100049001 tryptase precursor
     482135 CORIN; atrial natriuretic peptide-converting enzyme isoform X1
     100684133 OVCH1; LOW QUALITY PROTEIN: ovochymase-1 isoform X4
     485368 OVCH2; ovochymase-2 isoform X1
     477822 HABP2; hyaluronan-binding protein 2
     475521 cationic trypsin-like
     100686744 PRSS2; anionic trypsin
     487700 TMPRSS15; enteropeptidase
     102157328 PRSS8; prostasin
     100687821 PRSS12; neurotrypsin
     479874 testisin isoform X1
     106558941 testisin-like
     490056 PRSS22; brain-specific serine protease 4 isoform X1
     490057 PRSS27; serine protease 27 isoform X1
     482646 serine protease 27
     490053 PRSS33; serine protease 33
     490054 serine protease 33-like
     489924 PRSS36; polyserase-2 isoform X5
     102151573 PRSS53; serine protease 53 isoform X1
     610218 PRSS56; serine protease 56 isoform X1
     485099 PRSS57; serine protease 57
     475522 serine protease 58-like
     100688918 putative inactive serine protease 58 isoform X1
     478844 serine protease 58-like isoform X1
     442980 ELANE; neutrophil elastase precursor
     106559147 CTSG; cathepsin G
     487207 GZMA; granzyme A
     490630 GZMB; granzyme B
     490629 granzyme H isoform X1
     489200 GZMK; granzyme K
     490628 CMA1; chymase precursor
     403515 CELA1; chymotrypsin-like elastase family member 1 preproprotein
     478196 proproteinase E
     478220 chymotrypsin-C
     403942 KLK1; kallikrein-1 precursor
     403967 KLK2; arginine esterase precursor
     475624 KLKB1; plasma kallikrein
     484354 KLK4; kallikrein-4 precursor
     484353 KLK5; kallikrein-5 precursor
     476402 KLK6; kallikrein-6 precursor
     611780 KLK7; kallikrein-7 precursor
     484352 KLK8; kallikrein-8 isoform a precursor
     100329125 KLK9; kallikrein-9 precursor
     484351 KLK10; kallikrein-10 preproprotein
     476401 KLK11; kallikrein-11
     611766 KLK12; kallikrein-12 isoform X1
     100856194 KLK13; kallikrein-13 isoform X1
     484348 KLK14; kallikrein-14 precursor
     480822 kallikrein-15 isoform X2
     119870314 LOW QUALITY PROTEIN: kallikrein-15-like isoform X7
     486713 C1RL; complement C1r subcomponent-like protein isoform X2
     488121 MASP1; mannan-binding lectin serine protease 1 isoform X4
     487447 MASP2; mannan-binding lectin serine protease 2 isoform X2
     477707 C1R; complement C1r subcomponent
     486714 C1S; complement C1s subcomponent
     474853 C2; complement C2 isoform X1
     100688056 CFB; complement factor B
     485095 CFD; complement factor D isoform X1
     478515 CFI; complement factor I isoform X1
     100856539 F2; prothrombin
     607661 F7; coagulation factor VII precursor
     404015 F9; coagulation factor IX preproprotein
     476993 F10; coagulation factor X isoform X2
     475623 F11; coagulation factor XI precursor
     489090 F12; coagulation factor XII
     476104 PROC; vitamin K-dependent protein C precursor
     606765 ACR; acrosin isoform X1
     484583 HPN; serine protease hepsin isoform X2
     403432 HGFAC; hepatocyte growth factor activator precursor
     482840 PLAT; tissue-type plasminogen activator
     403426 PLAU; urokinase-type plasminogen activator precursor
     403602 PLG; plasminogen precursor
     487770 TMPRSS2; transmembrane protease serine 2 isoform X1
     610987 TMPRSS3; transmembrane protease serine 3 isoform X1
     489387 TMPRSS4; transmembrane protease serine 4 isoform X2
     611247 TMPRSS5; transmembrane protease serine 5 isoform X1
     608593 TMPRSS6; transmembrane protease serine 6
     487973 TMPRSS7; transmembrane protease serine 7
     612163 TMPRSS9; transmembrane protease serine 9 isoform X1
     482173 TMPRSS11A; LOW QUALITY PROTEIN: transmembrane protease serine 11A isoform X5
     482175 transmembrane protease serine 11B-like protein isoform X1
     100685482 LOW QUALITY PROTEIN: transmembrane protease serine 11B isoform X1
     482172 transmembrane protease serine 11C-like isoform X5
     611678 TMPRSS11D; transmembrane protease serine 11D isoform X5
     482176 transmembrane protease serine 11E
     482174 transmembrane protease serine 11F
     611685 transmembrane protease serine 11G-like
     610827 TMPRSS13; transmembrane protease serine 13 isoform X1
     611100 CTRL; chymotrypsin-like protease CTRL-1
     489278 ST14; suppressor of tumorigenicity 14 protein isoform X1
     479668 haptoglobin-like
     484768 MST1; hepatocyte growth factor-like protein isoform X2
     477852 HTRA1; serine protease HTRA1 isoform X5
     475782 HTRA2; serine protease HTRA2, mitochondrial
     100687287 HTRA3; serine protease HTRA3 isoform X7
     475580 HTRA4; serine protease HTRA4 isoform X3
     100687512 TYSND1; peroxisomal leader peptide-processing protease isoform X1
     485150 PRSS23; serine protease 23 isoform X1
K01310 CTRB; chymotrypsin [EC:3.4.21.1] 
K01310 CTRB; chymotrypsin [EC:3.4.21.1] 
K01340 E3.4.21.59; tryptase [EC:3.4.21.59] 
K09614 CORIN; atrial natriuretic peptide-converting enzyme [EC:3.4.21.-] 
K01362 OVCH; ovochymase [EC:3.4.21.-] 
K01362 OVCH; ovochymase [EC:3.4.21.-] 
K08648 HABP2; hyaluronan binding protein 2 [EC:3.4.21.-] 
K01312 PRSS1_2_3; trypsin [EC:3.4.21.4] 
K01312 PRSS1_2_3; trypsin [EC:3.4.21.4] 
K01316 TMPRSS15; enterokinase [EC:3.4.21.9] 
K08664 PRSS8; prostasin [EC:3.4.21.-] 
K09624 PRSS12; neurotrypsin [EC:3.4.21.-] 
K09625 PRSS21; testisin [EC:3.4.21.-] 
K09625 PRSS21; testisin [EC:3.4.21.-] 
K09626 PRSS22; brain-specific serine protease 4 [EC:3.4.21.-] 
K09628 PRSS27; serine protease 27 [EC:3.4.21.-] 
K09628 PRSS27; serine protease 27 [EC:3.4.21.-] 
K09629 PRSS33; serine protease 33 [EC:3.4.21.-] 
K09629 PRSS33; serine protease 33 [EC:3.4.21.-] 
K09630 PRSS36; polyserase 2 [EC:3.4.21.-] 
K25708 PRSS53; serine protease 53 [EC:3.4.21.-] 
K23440 PRSS56; serine protease 56 [EC:3.4.21.-] 
K23011 PRSS57; serine protease 57 [EC:3.4.21.-] 
K22367 PRSS58; serine protease 58 [EC:3.4.21.-] 
K22367 PRSS58; serine protease 58 [EC:3.4.21.-] 
K22367 PRSS58; serine protease 58 [EC:3.4.21.-] 
K01327 ELANE; leukocyte elastase [EC:3.4.21.37] 
K01319 CTSG; cathepsin G [EC:3.4.21.20] 
K01352 GZMA; granzyme A [EC:3.4.21.78] 
K01353 GZMB; granzyme B [EC:3.4.21.79] 
K09616 GZMH; granzyme H (cathepsin G-like 2) [EC:3.4.21.-] 
K08663 GZMK; granzyme K [EC:3.4.21.-] 
K01329 CMA1; chymase [EC:3.4.21.39] 
K01326 CELA1; pancreatic elastase I [EC:3.4.21.36] 
K01345 CELA3; pancreatic endopeptidase E [EC:3.4.21.70] 
K01311 CTRC; chymotrypsin C [EC:3.4.21.2] 
K01325 KLK1_2; tissue kallikrein [EC:3.4.21.35] 
K01325 KLK1_2; tissue kallikrein [EC:3.4.21.35] 
K01324 KLKB1; plasma kallikrein [EC:3.4.21.34] 
K08666 KLK4; kallikrein 4 [EC:3.4.21.-] 
K09617 KLK5; kallikrein 5 [EC:3.4.21.-] 
K08667 KLK6; kallikrein 6 [EC:3.4.21.-] 
K08668 KLK7; kallikrein 7 [EC:3.4.21.117] 
K08650 KLK8; kallikrein 8 [EC:3.4.21.118] 
K09618 KLK9; kallikrein 9 [EC:3.4.21.-] 
K09619 KLK10; kallikrein 10 [EC:3.4.21.-] 
K09620 KLK11; kallikrein 11 [EC:3.4.21.-] 
K09621 KLK12; kallikrein 12 [EC:3.4.21.-] 
K09463 KLK13; kallikrein 13 [EC:3.4.21.119] 
K09622 KLK14; kallikrein 14 [EC:3.4.21.-] 
K09623 KLK15; kallikrein 15 [EC:3.4.21.-] 
K09623 KLK15; kallikrein 15 [EC:3.4.21.-] 
K24791 C1RL; complement C1r subcomponent-like protein [EC:3.4.21.-] 
K03992 MASP1; mannan-binding lectin serine protease 1 [EC:3.4.21.-] 
K03993 MASP2; mannan-binding lectin serine protease 2 [EC:3.4.21.104] 
K01330 C1R; complement component 1, r subcomponent [EC:3.4.21.41] 
K01331 C1S; complement component 1, s subcomponent [EC:3.4.21.42] 
K01332 C2; complement component 2 [EC:3.4.21.43] 
K01335 CFB; complement factor B [EC:3.4.21.47] 
K01334 CFD; complement factor D [EC:3.4.21.46] 
K01333 CFI; complement factor I [EC:3.4.21.45] 
K01313 F2; coagulation factor II (thrombin) [EC:3.4.21.5] 
K01320 F7; coagulation factor VII [EC:3.4.21.21] 
K01321 F9; coagulation factor IX (Christmas factor) [EC:3.4.21.22] 
K01314 F10; coagulation factor X [EC:3.4.21.6] 
K01323 F11; coagulation factor XI [EC:3.4.21.27] 
K01328 F12; coagulation factor XII (Hageman factor) [EC:3.4.21.38] 
K01344 PROC; protein C (activated) [EC:3.4.21.69] 
K01317 ACR; acrosin [EC:3.4.21.10] 
K08665 HPN; hepsin [EC:3.4.21.106] 
K09631 HGFAC; hepatocyte growth factor activator [EC:3.4.21.-] 
K01343 PLAT; tissue plasminogen activator [EC:3.4.21.68] 
K01348 PLAU; urokinase plasminogen activator [EC:3.4.21.73] 
K01315 PLG; plasminogen [EC:3.4.21.7] 
K09633 TMPRSS2; transmembrane protease serine 2 [EC:3.4.21.122] 
K09634 TMPRSS3; transmembrane protease serine 3 [EC:3.4.21.-] 
K09635 TMPRSS4; transmembrane protease serine 4 [EC:3.4.21.-] 
K09636 TMPRSS5; transmembrane protease serine 5 [EC:3.4.21.-] 
K09637 TMPRSS6; transmembrane protease serine 6 [EC:3.4.21.-] 
K09638 TMPRSS7; transmembrane protease serine 7 [EC:3.4.21.-] 
K09640 TMPRSS9; transmembrane protease serine 9 [EC:3.4.21.-] 
K09750 TMPRSS11A; transmembrane protease serine 11A [EC:3.4.21.-] 
K09751 TMPRSS11B; transmembrane protease serine 11B [EC:3.4.21.-] 
K09751 TMPRSS11B; transmembrane protease serine 11B [EC:3.4.21.-] 
K14359 TMPRSS11C; transmembrane protease serine 11C [EC:3.4.21.-] 
K09641 TMPRSS11D; transmembrane protease serine 11D [EC:3.4.21.-] 
K09642 TMPRSS11E; transmembrane protease serine 11E [EC:3.4.21.-] 
K09752 TMPRSS11F; transmembrane protease serine 11F [EC:3.4.21.-] 
K18769 TMPRSS11G; transmembrane protease serine 11G [EC:3.4.21.-] 
K09643 TMPRSS13; transmembrane protease serine 13 
K09632 CTRL; chymotrypsin-like protease [EC:3.4.21.-] 
K08670 ST14; suppressor of tumorigenicity protein 14 [EC:3.4.21.109] 
K16142 HP; haptoglobin 
K23441 MST1; hepatocyte growth factor-like protein 
K08784 HTRA1; HtrA serine peptidase 1 [EC:3.4.21.-] 
K08669 HTRA2; HtrA serine peptidase 2 [EC:3.4.21.108] 
K08785 HTRA3; HtrA serine peptidase 3 [EC:3.4.21.-] 
K08786 HTRA4; HtrA serine peptidase 4 [EC:3.4.21.-] 
K23012 TYSND1; peroxisomal leader peptide-processing protease [EC:3.4.21.-] 
K09627 PRSS23; serine protease 23 [EC:3.4.21.-] 
   Family S3: togavirin family
   Family S6
   Family S7: flavivirin family
   Family S8: subtilisin family
   Family S9: prolyl oligopeptidase family
   Family S10
   Family S11: D-Ala-D-Ala carboxypeptidase A family
   Family S12: D-Ala-D-Ala carboxypeptidase B family
   Family S13: D-Ala-D-Ala peptidase C family
   Family S14: ClpP endopeptidase family
   Family S15
   Family S16: lon protease family
   Family S21: assemblin family
   Family S24: LexA family
   Family S26: signal peptidase I family
   Family S28
   Family S31
   Family S32
   Family S33
   Family S41: C-terminal processing peptidase family
   Family S45
   Family S49: protease IV family
   Family S50
   Family S51
   Family S53
   Family S54: Rhomboid family
   Family S55: SpoIVB peptidase family
   Family S62
   Family S66
   Family S77: phage prohead processing peptidase family
   Family S78
 
 Threonine peptidases
 
 Peptidases of unknown catalytic type
 
 Peptidase inhibitors

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Last updated: December 13, 2023
Classification taken and modified from MEROPS