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KO |
Eukaryotic type
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Sister chromatid cohesion proteins
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Meiosis-specific proteins
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Nucleosome assembly factors
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Histone modification proteins
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HATs (histone acetyltransferases)
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HAT complexes
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HDACs (histone deacetylases)
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HDAC complexes
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HMTs (histone methyltransferases)
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HKMTs (histone lysine methyltransferases)
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100754103 Ash1l; histone-lysine N-methyltransferase ASH1L isoform X1
100771005 Dot1l; histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X2
100754544 Ehmt1; histone-lysine N-methyltransferase EHMT1 isoform X10
100769417 Ehmt2; LOW QUALITY PROTEIN: histone-lysine N-methyltransferase EHMT2 isoform X2
100760595 Ezh1; histone-lysine N-methyltransferase EZH1 isoform X1
100758055 Ezh2; histone-lysine N-methyltransferase EZH2 isoform X1
100760424 Kmt2a; histone-lysine N-methyltransferase 2A isoform X2
100765465 Kmt2d; histone-lysine N-methyltransferase 2D isoform X2
100767367 Kmt2c; LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2C isoform X2
100750575 Kmt2b; histone-lysine N-methyltransferase 2B isoform X2
100756731 Kmt2e; inactive histone-lysine N-methyltransferase 2E isoform X1
100773206 Nsd1; histone-lysine N-methyltransferase, H3 lysine-36 specific isoform X1
100763780 Nsd2; histone-lysine N-methyltransferase NSD2 isoform X1
100773097 Nsd3; histone-lysine N-methyltransferase NSD3 isoform X1
103158597 Prdm2; PR domain zinc finger protein 2 isoform X5
100768628 Mecom; histone-lysine N-methyltransferase MECOM isoform X1
100773424 Prdm6; putative histone-lysine N-methyltransferase PRDM6 isoform X2
100752747 histone-lysine N-methyltransferase PRDM9 isoform X1
100763807 Prdm8; PR domain zinc finger protein 8 isoform X2
100772785 Znf488; zinc finger protein 488
100761986 Prdm12; PR domain zinc finger protein 12 isoform X2
100762301 Prdm16; histone-lysine N-methyltransferase PRDM16 isoform X4
100753294 Setd1b; LOW QUALITY PROTEIN: histone-lysine N-methyltransferase SETD1B isoform X2
100753962 Setd1a; histone-lysine N-methyltransferase SETD1A isoform X1
100765637 Setd2; histone-lysine N-methyltransferase SETD2 isoform X4
100753169 Setd4; SET domain-containing protein 4 isoform X3
100761490 Setd6; N-lysine methyltransferase SETD6
100767175 Setd7; histone-lysine N-methyltransferase SETD7 isoform X2
100774411 Kmt5a; N-lysine methyltransferase KMT5A isoform X2
100765697 Setdb1; histone-lysine N-methyltransferase SETDB1 isoform X2
100774155 Setdb2; histone-lysine N-methyltransferase SETDB2 isoform X1
100764148 histone-lysine N-methyltransferase SETMAR isoform X2
100766221 Smyd1; histone-lysine N-methyltransferase SMYD1 isoform X2
100761694 Smyd2; N-lysine methyltransferase SMYD2 isoform X2
100764840 Smyd3; histone-lysine N-methyltransferase SMYD3 isoform X1
100755145 Suv39h2; histone-lysine N-methyltransferase SUV39H2 isoform X2
100764568 Suv39h1; histone-lysine N-methyltransferase SUV39H1 isoform X3
100761878 Kmt5b; histone-lysine N-methyltransferase KMT5B isoform X3
100772952 Kmt5c; histone-lysine N-methyltransferase KMT5C isoform X2
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K06101 ASH1L; [histone H3]-lysine4 N-trimethyltransferase ASH1L [EC:2.1.1.354]
K11427 DOT1L; [histone H3]-lysine79 N-trimethyltransferase [EC:2.1.1.360]
K11420 EHMT; [histone H3]-lysine9 N-trimethyltransferase EHMT [EC:2.1.1.355]
K11420 EHMT; [histone H3]-lysine9 N-trimethyltransferase EHMT [EC:2.1.1.355]
K17451 EZH1; [histone H3]-lysine27 N-trimethyltransferase EZH1 [EC:2.1.1.356]
K11430 EZH2; [histone H3]-lysine27 N-trimethyltransferase EZH2 [EC:2.1.1.356]
K09186 MLL1; [histone H3]-lysine4 N-trimethyltransferase MLL1 [EC:2.1.1.354]
K09187 MLL2; [histone H3]-lysine4 N-trimethyltransferase MLL2 [EC:2.1.1.354]
K09188 MLL3; [histone H3]-lysine4 N-trimethyltransferase MLL3 [EC:2.1.1.354]
K14959 MLL4; [histone H3]-lysine4 N-trimethyltransferase MLL4 [EC:2.1.1.354]
K09189 MLL5; [histone H3]-lysine4 N-trimethyltransferase MLL5 [EC:2.1.1.354]
K15588 NSD1; [histone H3]-lysine36 N-dimethyltransferase NSD1 [EC:2.1.1.357]
K11424 WHSC1; [histone H3]-lysine36 N-dimethyltransferase NSD2 [EC:2.1.1.357]
K11425 WHSC1L1; [histone H3]-lysine4 N-dimethyltransferase / [histone H3]-lysine27 N-dimethyltransferase [EC:2.1.1.370 2.1.1.371]
K11432 PRDM2; [histone H3]-lysine9 N-trimethyltransferase PRDM2 [EC:2.1.1.355]
K04462 MECOM; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
K20795 PRDM6; [histone H4]-lysine20 N-methyltransferase PRDM6 [EC:2.1.1.361]
K20796 PRDM7_9; [histone H3]-lysine4 N-trimethyltransferase PRDM7/9 [EC:2.1.1.354]
K20797 PRDM8; PR domain zinc finger protein 8 [EC:2.1.1.-]
K20797 PRDM8; PR domain zinc finger protein 8 [EC:2.1.1.-]
K24255 PRDM12; PR domain zinc finger protein 12 [EC:2.1.1.-]
K22410 PRDM16; [histone H3]-lysine9 N-methyltransferase [EC:2.1.1.367]
K11422 SETD1; [histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:2.1.1.354]
K11422 SETD1; [histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:2.1.1.354]
K11423 SETD2; [histone H3]-lysine36 N-trimethyltransferase [EC:2.1.1.359]
K27277 SETD4; SET domain-containing protein 4 [EC:2.1.1.- 2.1.1.364]
K05302 SETD6; N-lysine methyltransferase SETD6 [EC:2.1.1.-]
K11431 SETD7; [histone H3]-lysine4 N-methyltransferase [EC:2.1.1.364]
K11428 SETD8; [histone H4]-lysine20 N-methyltransferase SETD8 [EC:2.1.1.361]
K11421 SETDB1; [histone H3]-N6,N6-dimethyl-lysine9 N-methyltransferase [EC:2.1.1.366]
K18494 SETDB2; [histone H3]-lysine9 N-trimethyltransferase SETDB2 [EC:2.1.1.355]
K11433 SETMAR; [histone H3]-lysine36 N-dimethyltransferase SETMAR [EC:2.1.1.357]
K11426 SMYD; [histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:2.1.1.354 2.1.1.357]
K11426 SMYD; [histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:2.1.1.354 2.1.1.357]
K11426 SMYD; [histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:2.1.1.354 2.1.1.357]
K11419 SUV39H; [histone H3]-lysine9 N-trimethyltransferase SUV39H [EC:2.1.1.355]
K11419 SUV39H; [histone H3]-lysine9 N-trimethyltransferase SUV39H [EC:2.1.1.355]
K11429 SUV420H; [histone H4]-N-methyl-L-lysine20 N-methyltransferase [EC:2.1.1.362]
K11429 SUV420H; [histone H4]-N-methyl-L-lysine20 N-methyltransferase [EC:2.1.1.362]
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PRMTs (protein arginine metyltransferases)
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HMT complexes
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Histone demethylases
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Polycomb repressive complex (PRC) and associated proteins
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Sir proteins
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Other histone modification proteins
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Chromosome condensation proteins
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Centromeric chromatin formation proteins
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Heterochromatin formation proteins
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Gene silencing
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Centrosome formation proteins
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Sister chromatid separation proteins
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Chromatin remodeling factors
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Prokaryotic type
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