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1. Oxidoreductases
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2. Transferases
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3. Hydrolases
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4. Lyases
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5. Isomerases
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6. Ligases
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6.1 Forming carbon-oxygen bonds
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6.2 Forming carbon-sulfur bonds
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6.3 Forming carbon-nitrogen bonds
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6.4 Forming carbon-carbon bonds
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6.5 Forming phosphoric-ester bonds
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6.5.1 Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
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6.5.1.1 DNA ligase (ATP)
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103503033 DNA ligase 1 isoform X1
103492544 DNA ligase 4 isoform X2
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K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
K10777 LIG4; DNA ligase 4 [EC:6.5.1.1]
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6.5.1.2 DNA ligase (NAD+)
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6.5.1.3 RNA ligase (ATP)
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6.5.1.4 RNA 3'-terminal-phosphate cyclase (ATP)
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6.5.1.5 RNA 3'-terminal-phosphate cyclase (GTP)
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6.5.1.6 DNA ligase (ATP or NAD+)
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6.5.1.7 DNA ligase (ATP, ADP or GTP)
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6.5.1.8 3'-phosphate/5'-hydroxy nucleic acid ligase
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6.5.1.9 cyclic 2,3-diphosphoglycerate synthase
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6.6 Forming nitrogen-metal bonds
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6.7 Forming nitrogen-nitrogen bonds
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7. Translocases
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