KEGG Orthology (KO) - Ficedula albicollis (collared flycatcher)

[ Brite menu | Download htext | Download json | Help ]
Search

1st Level  2nd Level  3rd Level  4th Level 

     KO
 09100 Metabolism
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
   09131 Membrane transport
 
   09132 Signal transduction
     02020 Two-component system
     04010 MAPK signaling pathway [PATH:fab04010]
     04013 MAPK signaling pathway - fly
     04016 MAPK signaling pathway - plant
     04011 MAPK signaling pathway - yeast
     04012 ErbB signaling pathway [PATH:fab04012]
       101819290 EGF; epidermal growth factor
       101809051 AREG; amphiregulin
       101818290 EGFR; epidermal growth factor receptor
       101818019 ERBB2; erb-b2 receptor tyrosine kinase 2
       101820005 1-phosphatidylinositol 4
       101806517 PLCG1; phospholipase C gamma 1
       101811465 PLCG2; phospholipase C gamma 2
       101810626 CAMK2A; calcium/calmodulin dependent protein kinase II alpha
       101806876 CAMK2D; calcium/calmodulin dependent protein kinase II delta
       101817363 CAMK2B; calcium/calmodulin dependent protein kinase II beta
       101812759 CAMK2G; calcium/calmodulin dependent protein kinase II gamma
       101810891 PRKCA; protein kinase C alpha
       101820883 PRKCB; protein kinase C beta
       101810639 CBL; Cbl proto-oncogene
       101810847 CBLB; Cbl proto-oncogene B
       101808879 STAT5B; signal transducer and activator of transcription 5B
       101809008 SRC; SRC proto-oncogene, non-receptor tyrosine kinase
       101814936 PTK2; protein tyrosine kinase 2
       101808629 CRKL; CRK like proto-oncogene, adaptor protein
       101807715 CRK; CRK proto-oncogene, adaptor protein
       101817037 ABL1; ABL proto-oncogene 1, non-receptor tyrosine kinase
       101815859 ABL2; ABL proto-oncogene 2, non-receptor tyrosine kinase
       101811171 NCK2; NCK adaptor protein 2
       101820258 PAK1; p21 (RAC1) activated kinase 1
       101810304 PAK2; p21 (RAC1) activated kinase 2
       101810521 serine/threonine-protein kinase PAK 3-like
       101816729 serine/threonine-protein kinase PAK 3-like
       101808892 serine/threonine-protein kinase PAK 3
       101819134 serine/threonine-protein kinase PAK 3-like
       101815267 PAK3; p21 (RAC1) activated kinase 3
       101810542 PAK5; p21 (RAC1) activated kinase 5
       101822249 PAK6; p21 (RAC1) activated kinase 6
       101822010 MAP2K4; mitogen-activated protein kinase kinase 4
       101812216 dual specificity mitogen-activated protein kinase kinase 7-like
       101809052 MAPK10; mitogen-activated protein kinase 10
       101819306 MAPK9; mitogen-activated protein kinase 9
       101817339 MAPK8; mitogen-activated protein kinase 8
       101816255 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
       101811254 BTC; betacellulin
       101808558 HBEGF; heparin binding EGF like growth factor
       101808722 EREG; epiregulin
       101814316 NRG1; neuregulin 1
       101815225 NRG2; neuregulin 2
       101808540 ERBB4; erb-b2 receptor tyrosine kinase 4
       101807411 SHC1; SHC adaptor protein 1
       101815242 SHC2; SHC adaptor protein 2
       101820104 SHC3; SHC adaptor protein 3
       101809679 SHC4; SHC adaptor protein 4
       101812321 GRB2; growth factor receptor bound protein 2
       101809111 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
       101818186 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
       101811520 HRAS; HRas proto-oncogene, GTPase
       101809651 KRAS; KRAS proto-oncogene, GTPase
       101813585 NRAS; neuroblastoma RAS viral oncogene homolog
       101806469 BRAF; B-Raf proto-oncogene, serine/threonine kinase
       101816261 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
       101816905 MAP2K1; mitogen-activated protein kinase kinase 1
       101820507 MAP2K2; mitogen-activated protein kinase kinase 2
       101815088 MAPK1; mitogen-activated protein kinase 1
       101819732 MYC; v-myc avian myelocytomatosis viral oncogene homolog
       101813104 GAB1; GRB2 associated binding protein 1
       101811334 NRG3; neuregulin 3
       101814037 NRG4; neuregulin 4
       101811931 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       101821801 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       101814811 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       101820843 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
       101811808 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
       101812251 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
       101819472 AKT3; AKT serine/threonine kinase 3
       101814876 AKT1; AKT serine/threonine kinase 1
       101820693 MTOR; mechanistic target of rapamycin
       101810135 RPS6KB1; ribosomal protein S6 kinase B1
       101817600 RPS6KB2; ribosomal protein S6 kinase B2
       101807423 GSK3B; glycogen synthase kinase 3 beta
       101811953 CDKN1B; cyclin dependent kinase inhibitor 1B
       101811025 CDKN1A; cyclin dependent kinase inhibitor 1A
K04357 EGF; epidermal growth factor
K09782 AREG; amphiregulin
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K22517 CBLB; E3 ubiquitin-protein ligase CBL-B [EC:2.3.2.27]
K11224 STAT5B; signal transducer and activator of transcription 5B
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K08887 ABL2; abelson tyrosine-protein kinase 2 [EC:2.7.10.2]
K19862 NCK2; NCK adaptor protein 2
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3; p21-activated kinase 3 [EC:2.7.11.1]
K05733 PAK3; p21-activated kinase 3 [EC:2.7.11.1]
K05733 PAK3; p21-activated kinase 3 [EC:2.7.11.1]
K05733 PAK3; p21-activated kinase 3 [EC:2.7.11.1]
K05733 PAK3; p21-activated kinase 3 [EC:2.7.11.1]
K05736 PAK5; p21-activated kinase 5 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K04430 MAP2K4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K09783 BTC; betacellulin
K08523 HBEGF; heparin-binding EGF-like growth factor
K09784 EREG; epiregulin
K05455 NRG1; neuregulin 1
K05456 NRG2; neuregulin 2
K05085 ERBB4; receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04377 MYC; Myc proto-oncogene protein
K09593 GAB1; GRB2-associated-binding protein 1
K05457 NRG3; neuregulin 3
K05458 NRG4; neuregulin 4
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
     04014 Ras signaling pathway
     04015 Rap1 signaling pathway
     04310 Wnt signaling pathway [PATH:fab04310]
     04330 Notch signaling pathway [PATH:fab04330]
     04340 Hedgehog signaling pathway [PATH:fab04340]
     04341 Hedgehog signaling pathway - fly
     04350 TGF-beta signaling pathway [PATH:fab04350]
     04390 Hippo signaling pathway
     04391 Hippo signaling pathway - fly
     04392 Hippo signaling pathway - multiple species
     04370 VEGF signaling pathway [PATH:fab04370]
     04371 Apelin signaling pathway [PATH:fab04371]
     04630 JAK-STAT signaling pathway
     04064 NF-kappa B signaling pathway
     04668 TNF signaling pathway
     04066 HIF-1 signaling pathway
     04068 FoxO signaling pathway [PATH:fab04068]
       101818496 TGFB1; transforming growth factor beta-1
       101814341 TGFB2; transforming growth factor beta 2
       101809258 TGFB3; transforming growth factor beta 3
       101809241 TGFBR1; transforming growth factor beta receptor 1
       101811048 TGFBR2; transforming growth factor beta receptor 2
       101808986 TGF-beta receptor type-2-like
       101806307 SMAD3; SMAD family member 3
       101809216 STK11; serine/threonine kinase 11
       101811154 PRKAA2; protein kinase AMP-activated catalytic subunit alpha 2
       101809698 PRKAA1; protein kinase AMP-activated catalytic subunit alpha 1
       101807095 PRKAB1; protein kinase AMP-activated non-catalytic subunit beta 1
       101807509 PRKAB2; protein kinase AMP-activated non-catalytic subunit beta 2
       101811942 PRKAG1; protein kinase AMP-activated non-catalytic subunit gamma 1
       101821783 PRKAG2; protein kinase AMP-activated non-catalytic subunit gamma 2
       101819371 PRKAG3; protein kinase AMP-activated non-catalytic subunit gamma 3
       101817298 NLK; nemo like kinase
       101810388 SKP2; S-phase kinase associated protein 2
       101813089 MDM2; MDM2 proto-oncogene
       101807375 SETD7; SET domain containing lysine methyltransferase 7
       101809867 CREBBP; CREB binding protein
       101810784 EP300; E1A binding protein p300
       101810475 SIRT1; sirtuin 1
       101807896 USP7; ubiquitin specific peptidase 7
       101809052 MAPK10; mitogen-activated protein kinase 10
       101819306 MAPK9; mitogen-activated protein kinase 9
       101817339 MAPK8; mitogen-activated protein kinase 8
       101805689 STK4; serine/threonine kinase 4
       101808710 IGF1; insulin like growth factor 1
       101819893 IGF1R; insulin like growth factor 1 receptor
       101812165 INS; insulin
       101813861 INSR; insulin receptor
       101810426 IRS1; insulin receptor substrate 1
       101814066 IRS2; insulin receptor substrate 2
       101807499 IRS4; insulin receptor substrate 4
       101811931 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       101821801 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       101814811 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       101820843 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
       101811808 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
       101812251 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
       101813442 PDPK1; 3-phosphoinositide dependent protein kinase 1
       101812706 CHUK; conserved helix-loop-helix ubiquitous kinase
       101809821 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
       101815785 PTEN; phosphatase and tensin homolog
       101819472 AKT3; AKT serine/threonine kinase 3
       101814876 AKT1; AKT serine/threonine kinase 1
       101810101 SGK1; serine/threonine-protein kinase Sgk1
       101813648 SGK2; SGK2, serine/threonine kinase 2
       101821448 SGK3; serine/threonine-protein kinase Sgk3
       101809090 FOXO1; forkhead box O1
       101810105 FOXO3; forkhead box O3
       101808791 FOXO4; forkhead box O4
       101812063 FOXO6; forkhead box O6
       101807135 GRM1; glutamate metabotropic receptor 1
       101807893 HOMER2; homer scaffolding protein 2
       101806140 HOMER1; homer scaffolding protein 1
       101809364 HOMER3; homer scaffolding protein 3
       101817781 CSNK1E; casein kinase I
       101806545 IL6; interleukin 6
       101814435 IL10; interleukin 10
       101809631 STAT3; signal transducer and activator of transcription 3
       101819290 EGF; epidermal growth factor
       101818290 EGFR; epidermal growth factor receptor
       101812321 GRB2; growth factor receptor bound protein 2
       101809111 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
       101818186 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
       101811520 HRAS; HRas proto-oncogene, GTPase
       101809651 KRAS; KRAS proto-oncogene, GTPase
       101813585 NRAS; neuroblastoma RAS viral oncogene homolog
       101806469 BRAF; B-Raf proto-oncogene, serine/threonine kinase
       101816261 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
       101816905 MAP2K1; mitogen-activated protein kinase kinase 1
       101820507 MAP2K2; mitogen-activated protein kinase kinase 2
       101815088 MAPK1; mitogen-activated protein kinase 1
       101819980 MAPK14; mitogen-activated protein kinase 14
       101817434 MAPK13; mitogen-activated protein kinase 13
       101807358 MAPK12; mitogen-activated protein kinase 12
       101814783 MAPK11; mitogen-activated protein kinase 11
       101809466 FOXG1; forkhead box G1
       101815219 CCNB2; cyclin B2
       101815007 CCNB3; cyclin B3
       101806043 G2/mitotic-specific cyclin-B3-like
       101807319 CCND1; cyclin D1
       101818224 CCND2; cyclin D2
       101815914 CCNG2; cyclin G2
       101815251 cyclin-dependent kinase inhibitor 2A-like
       101815443 cyclin-dependent kinase 4 inhibitor B-like
       101811025 CDKN1A; cyclin dependent kinase inhibitor 1A
       101811953 CDKN1B; cyclin dependent kinase inhibitor 1B
       101806783 RBL2; RB transcriptional corepressor like 2
       101821878 PLK1; polo like kinase 1
       101808952 PLK2; polo like kinase 2
       101813168 PLK3; polo like kinase 3
       101806039 PLK4; polo like kinase 4
       101821221 GADD45G; growth arrest and DNA damage inducible gamma
       101820749 FASLG; Fas ligand
       101819287 BCL2L11; BCL2 like 11
       101806118 TNFSF10; tumor necrosis factor superfamily member 10
       101805742 BCL6; B-cell CLL/lymphoma 6
       101809736 BNIP3; BCL2 interacting protein 3
       101806431 BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like
       101814814 GABARAPL2; GABA type A receptor associated protein like 2
       101806792 GABARAPL1; GABA type A receptor associated protein like 1
       101813162 CAT; catalase
       101814531 SOD2; superoxide dismutase 2
       101810210 ATM; ATM serine/threonine kinase
       101812323 PCK1; phosphoenolpyruvate carboxykinase 1
       101814845 G6PC3; glucose-6-phosphatase 3
       101813511 G6PC; glucose-6-phosphatase catalytic subunit
       101820224 G6PC2; glucose-6-phosphatase catalytic subunit 2
       101816330 IL7R; interleukin 7 receptor
       101808694 KLF2; Kruppel like factor 2
       101813362 Krueppel-like factor 2
       101821933 S1PR1; sphingosine-1-phosphate receptor 1
       101814439 S1PR4; sphingosine-1-phosphate receptor 4
       101817279 RAG1; recombination activating 1
       101817082 RAG2; recombination activating 2
       101820210 FBXO32; F-box protein 32
       101822114 FBXO25; F-box protein 25
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K23605 SMAD3; mothers against decapentaplegic homolog 3
K07298 STK11; serine/threonine-protein kinase 11 [EC:2.7.11.1]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K04468 NLK; nemo like kinase [EC:2.7.11.24]
K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K11431 SETD7; [histone H3]-lysine4 N-methyltransferase [EC:2.1.1.364]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K11411 SIRT1; NAD+-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04411 STK4; serine/threonine kinase 4
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04526 INS; insulin
K04527 INSR; insulin receptor [EC:2.7.10.1]
K16172 IRS1; insulin receptor substrate 1
K07187 IRS2; insulin receptor substrate 2
K07187 IRS2; insulin receptor substrate 2
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K13302 SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
K13303 SGK2; serum/glucocorticoid-regulated kinase 2 [EC:2.7.11.1]
K13304 SGK3; serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1]
K07201 FOXO1; forkhead box protein O1
K09408 FOXO3; forkhead box protein O3
K12358 FOXO4; forkhead box protein O4
K17847 FOXO6; forkhead box protein O6
K04603 GRM1; metabotropic glutamate receptor 1
K15010 HOMER; homer
K15010 HOMER; homer
K15010 HOMER; homer
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K05405 IL6; interleukin 6
K05443 IL10; interleukin 10
K04692 STAT3; signal transducer and activator of transcription 3
K04357 EGF; epidermal growth factor
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K09385 FOXG; forkhead box protein G
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K21771 CCNB3; G2/mitotic-specific cyclin-B3
K21771 CCNB3; G2/mitotic-specific cyclin-B3
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10146 CCNG2; cyclin G2
K04685 CDKN2B; cyclin-dependent kinase inhibitor 2B
K04685 CDKN2B; cyclin-dependent kinase inhibitor 2B
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K16332 RBL2; retinoblastoma-like protein 2
K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
K08861 PLK2; polo-like kinase 2 [EC:2.7.11.21]
K08862 PLK3; polo-like kinase 3 [EC:2.7.11.21]
K08863 PLK4; polo-like kinase 4 [EC:2.7.11.21]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K16341 BCL2L11; Bcl-2-like protein 11
K04721 TNFSF10; tumor necrosis factor ligand superfamily member 10
K15618 BCL6; B-cell lymphoma 6 protein
K15464 BNIP3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
K15464 BNIP3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
K08341 GABARAP; GABA(A) receptor-associated protein
K08341 GABARAP; GABA(A) receptor-associated protein
K03781 katE; catalase [EC:1.11.1.6]
K04564 SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K05072 IL7R; interleukin 7 receptor
K17845 KLF2; krueppel-like factor 2
K17845 KLF2; krueppel-like factor 2
K04288 S1PR1; sphingosine 1-phosphate receptor 1
K04293 S1PR4; sphingosine 1-phosphate receptor 4
K10628 RAG1; V(D)J recombination-activating protein 1 [EC:2.3.2.27]
K10988 RAG2; recombination-activating protein 2
K10305 FBXO25_32; F-box protein 25/32
K10305 FBXO25_32; F-box protein 25/32
     04020 Calcium signaling pathway [PATH:fab04020]
     04070 Phosphatidylinositol signaling system [PATH:fab04070]
     04072 Phospholipase D signaling pathway
     04071 Sphingolipid signaling pathway
     04024 cAMP signaling pathway
     04022 cGMP-PKG signaling pathway
     04151 PI3K-Akt signaling pathway
     04152 AMPK signaling pathway
     04150 mTOR signaling pathway [PATH:fab04150]
     04075 Plant hormone signal transduction
 
   09133 Signaling molecules and interaction
 
 09140 Cellular Processes
 
   09141 Transport and catabolism
 
   09143 Cell growth and death
     04110 Cell cycle [PATH:fab04110]
       101807319 CCND1; cyclin D1
       101818224 CCND2; cyclin D2
       101819978 CCND3; cyclin D3
       101815768 CDK6; cyclin dependent kinase 6
       101806985 RB1; RB transcriptional corepressor 1
       101816601 RBL1; RB transcriptional corepressor like 1
       101806783 RBL2; RB transcriptional corepressor like 2
       101817037 ABL1; ABL proto-oncogene 1, non-receptor tyrosine kinase
       101819193 HDAC1; histone deacetylase 1
       101809249 HDAC2; histone deacetylase 2
       101808436 E2F1; E2F transcription factor 1
       101805813 E2F2; E2F transcription factor 2
       101815458 E2F3; E2F transcription factor 3
       101806563 E2F4; E2F transcription factor 4
       101817008 E2F5; E2F transcription factor 5
       101822021 TFDP1; transcription factor Dp-1
       101808031 TFDP2; transcription factor Dp-2
       101807423 GSK3B; glycogen synthase kinase 3 beta
       101818496 TGFB1; transforming growth factor beta-1
       101814341 TGFB2; transforming growth factor beta 2
       101809258 TGFB3; transforming growth factor beta 3
       101818681 SMAD2; SMAD family member 2
       101806307 SMAD3; SMAD family member 3
       101819732 MYC; v-myc avian myelocytomatosis viral oncogene homolog
       101816016 ZBTB17; zinc finger and BTB domain containing 17
       101815251 cyclin-dependent kinase inhibitor 2A-like
       101815443 cyclin-dependent kinase 4 inhibitor B-like
       101815473 CDKN2C; cyclin dependent kinase inhibitor 2C
       101811953 CDKN1B; cyclin dependent kinase inhibitor 1B
       101811025 CDKN1A; cyclin dependent kinase inhibitor 1A
       101821269 CCNE1; cyclin E1
       101809310 CCNE2; cyclin E2
       101813841 SKP1; S-phase kinase associated protein 1
       101810352 CUL1; cullin 1
       101806409 RBX1; ring-box 1
       101810388 SKP2; S-phase kinase associated protein 2
       101806462 CCNA1; cyclin A1
       101807947 CCNA2; cyclin A2
       101815034 CDC6; cell division cycle 6
       101808430 CDC45; cell division cycle 45
       101807032 CDC7; cell division cycle 7
       101820856 DBF4; DBF4 zinc finger
       101821925 CDK1; cyclin dependent kinase 1
       101815219 CCNB2; cyclin B2
       101815007 CCNB3; cyclin B3
       101806043 G2/mitotic-specific cyclin-B3-like
       101817573 M-phase inducer phosphatase 2-like
       101818104 YWHAZ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
       101822146 YWHAB; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
       101814533 YWHAQ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
       101807403 YWHAE; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
       101814483 YWHAH; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
       101805807 YWHAG; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
       101821878 PLK1; polo like kinase 1
       101806666 WEE2; WEE1 homolog 2
       101819816 WEE1; WEE1 G2 checkpoint kinase
       101808888 CCNH; cyclin H
       101821891 CDK7; cyclin dependent kinase 7
       101819470 ANAPC1; anaphase promoting complex subunit 1
       101821144 ANAPC2; anaphase promoting complex subunit 2
       101817437 CDC27; cell division cycle 27
       101807496 ANAPC4; anaphase promoting complex subunit 4
       101815156 ANAPC5; anaphase promoting complex subunit 5
       101806086 CDC16; cell division cycle 16
       101816780 ANAPC7; anaphase promoting complex subunit 7
       101812010 CDC23; cell division cycle 23
       101807314 ANAPC10; anaphase promoting complex subunit 10
       101807401 ANAPC11; anaphase promoting complex subunit 11
       101820166 CDC26; cell division cycle 26
       101818060 ANAPC13; anaphase promoting complex subunit 13
       101811655 CDC20; cell division cycle 20
       101819185 PTTG1; pituitary tumor-transforming 1
       101815518 SMC1B; structural maintenance of chromosomes 1B
       101811259 SMC3; structural maintenance of chromosomes 3
       101813928 cohesin subunit SA-2-like
       101819042 STAG2; stromal antigen 2
       101821072 STAG1; stromal antigen 1
       101815459 RAD21; RAD21 cohesin complex component
       101818011 RAD21L1; RAD21 cohesin complex component like 1
       101819351 TTK; TTK protein kinase
       101819085 BUB1; BUB1 mitotic checkpoint serine/threonine kinase
       101819485 BUB3; BUB3, mitotic checkpoint protein
       101822055 BUB1B; BUB1 mitotic checkpoint serine/threonine kinase B
       101818325 MAD1L1; MAD1 mitotic arrest deficient like 1
       101815586 MAD2L1; MAD2 mitotic arrest deficient-like 1 (yeast)
       101818807 MAD2L2; MAD2 mitotic arrest deficient-like 2 (yeast)
       101807726 FZR1; fizzy/cell division cycle 20 related 1
       101817690 CDC14B; cell division cycle 14B
       101820750 EXTL2; exostosin like glycosyltransferase 2
       101809341 ATR; ATR serine/threonine kinase
       101810210 ATM; ATM serine/threonine kinase
       101815748 CHEK1; checkpoint kinase 1
       101811158 CHEK2; checkpoint kinase 2
       101809867 CREBBP; CREB binding protein
       101810784 EP300; E1A binding protein p300
       101819416 PRKDC; protein kinase, DNA-activated, catalytic polypeptide
       101813089 MDM2; MDM2 proto-oncogene
       101821221 GADD45G; growth arrest and DNA damage inducible gamma
       101812857 PCNA; proliferating cell nuclear antigen
       101815491 SFN; stratifin
       101816817 CDC25A; cell division cycle 25A
       101818989 ORC1; origin recognition complex subunit 1
       101807028 ORC2; origin recognition complex subunit 2
       101810289 ORC3; origin recognition complex subunit 3
       101820417 ORC4; origin recognition complex subunit 4
       101813528 ORC5; origin recognition complex subunit 5
       101809746 ORC6; origin recognition complex subunit 6
       101817290 MCM2; minichromosome maintenance complex component 2
       101812295 MCM3; minichromosome maintenance complex component 3
       101807243 MCM4; minichromosome maintenance complex component 4
       101816882 MCM5; minichromosome maintenance complex component 5
       101816837 MCM6; minichromosome maintenance complex component 6
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K04681 RBL1; retinoblastoma-like protein 1
K16332 RBL2; retinoblastoma-like protein 2
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04682 E2F4_5; transcription factor E2F4/5
K04682 E2F4_5; transcription factor E2F4/5
K04683 TFDP1; transcription factor Dp-1
K09392 TFDP2; transcription factor Dp-2
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04377 MYC; Myc proto-oncogene protein
K10500 ZBTB17; zinc finger and BTB domain-containing protein 17
K04685 CDKN2B; cyclin-dependent kinase inhibitor 2B
K04685 CDKN2B; cyclin-dependent kinase inhibitor 2B
K06622 CDKN2C; cyclin-dependent kinase inhibitor 2C
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K03094 SKP1; S-phase kinase-associated protein 1
K03347 CUL1; cullin 1
K03868 RBX1; RING-box protein 1 [EC:2.3.2.32]
K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K02213 CDC6; cell division control protein 6
K06628 CDC45; cell division control protein 45
K02214 CDC7; cell division control protein 7 [EC:2.7.11.1]
K06629 ASK; activator of S phase kinase
K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K21771 CCNB3; G2/mitotic-specific cyclin-B3
K21771 CCNB3; G2/mitotic-specific cyclin-B3
K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K06630 YWHAE; 14-3-3 protein epsilon
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
K06634 CCNH; cyclin H
K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
K03348 APC1; anaphase-promoting complex subunit 1
K03349 APC2; anaphase-promoting complex subunit 2
K03350 APC3; anaphase-promoting complex subunit 3
K03351 APC4; anaphase-promoting complex subunit 4
K03352 APC5; anaphase-promoting complex subunit 5
K03353 APC6; anaphase-promoting complex subunit 6
K03354 APC7; anaphase-promoting complex subunit 7
K03355 APC8; anaphase-promoting complex subunit 8
K03357 APC10; anaphase-promoting complex subunit 10
K03358 APC11; anaphase-promoting complex subunit 11
K03359 APC12; anaphase-promoting complex subunit 12
K12456 APC13; anaphase-promoting complex subunit 13
K03363 CDC20; cell division cycle 20, cofactor of APC complex
K06635 PTTG; securin
K06636 SMC1; structural maintenance of chromosome 1
K06669 SMC3; structural maintenance of chromosome 3 (chondroitin sulfate proteoglycan 6)
K06671 STAG1_2; cohesin complex subunit SA-1/2
K06671 STAG1_2; cohesin complex subunit SA-1/2
K06671 STAG1_2; cohesin complex subunit SA-1/2
K06670 SCC1; cohesin complex subunit SCC1
K06670 SCC1; cohesin complex subunit SCC1
K08866 TTK; serine/threonine-protein kinase TTK/MPS1 [EC:2.7.12.1]
K02178 BUB1; checkpoint serine/threonine-protein kinase [EC:2.7.11.1]
K02180 BUB3; cell cycle arrest protein BUB3
K06637 BUB1B; mitotic checkpoint serine/threonine-protein kinase BUB1 beta [EC:2.7.11.1]
K06679 MAD1; mitotic spindle assembly checkpoint protein MAD1
K02537 MAD2; mitotic spindle assembly checkpoint protein MAD2
K13728 MAD2L2; mitotic spindle assembly checkpoint protein MAD2B
K03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
K06639 CDC14; cell division cycle 14 [EC:3.1.3.16 3.1.3.48]
K06639 CDC14; cell division cycle 14 [EC:3.1.3.16 3.1.3.48]
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04802 PCNA; proliferating cell nuclear antigen
K06644 SFN; stratifin
K06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
K02603 ORC1; origin recognition complex subunit 1
K02604 ORC2; origin recognition complex subunit 2
K02605 ORC3; origin recognition complex subunit 3
K02606 ORC4; origin recognition complex subunit 4
K02607 ORC5; origin recognition complex subunit 5
K02608 ORC6; origin recognition complex subunit 6
K02540 MCM2; DNA replication licensing factor MCM2 [EC:3.6.4.12]
K02541 MCM3; DNA replication licensing factor MCM3 [EC:3.6.4.12]
K02212 MCM4; DNA replication licensing factor MCM4 [EC:3.6.4.12]
K02209 MCM5; DNA replication licensing factor MCM5 [EC:3.6.4.12]
K02542 MCM6; DNA replication licensing factor MCM6 [EC:3.6.4.12]
     04111 Cell cycle - yeast
     04112 Cell cycle - Caulobacter
     04113 Meiosis - yeast
     04114 Oocyte meiosis [PATH:fab04114]
     04210 Apoptosis [PATH:fab04210]
     04214 Apoptosis - fly
     04215 Apoptosis - multiple species
     04216 Ferroptosis [PATH:fab04216]
     04217 Necroptosis [PATH:fab04217]
     04115 p53 signaling pathway [PATH:fab04115]
       101810210 ATM; ATM serine/threonine kinase
       101811158 CHEK2; checkpoint kinase 2
       101809341 ATR; ATR serine/threonine kinase
       101815748 CHEK1; checkpoint kinase 1
       101807775 GORAB; golgin, RAB6 interacting
       101813089 MDM2; MDM2 proto-oncogene
       101810700 MDM4; MDM4, p53 regulator
       101811025 CDKN1A; cyclin dependent kinase inhibitor 1A
       101807319 CCND1; cyclin D1
       101818224 CCND2; cyclin D2
       101819978 CCND3; cyclin D3
       101815768 CDK6; cyclin dependent kinase 6
       101821269 CCNE1; cyclin E1
       101809310 CCNE2; cyclin E2
       101815491 SFN; stratifin
       101816378 RPRM; reprimo, TP53 dependent G2 arrest mediator candidate
       101815219 CCNB2; cyclin B2
       101821925 CDK1; cyclin dependent kinase 1
       101821221 GADD45G; growth arrest and DNA damage inducible gamma
       101806153 GTSE1; G2 and S-phase expressed 1
       101806294 FAS; Fas cell surface death receptor
       101822122 PIDD1; p53-induced death domain protein 1
       101816790 TNFRSF10A; tumor necrosis factor receptor superfamily member 10A
       101820140 tumor necrosis factor receptor superfamily member 23-like
       101815602 caspase-8-like
       101814031 caspase-8-like
       101821709 BID; BH3 interacting domain death agonist
       107604289 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
       101808217 SIVA1; SIVA1 apoptosis inducing factor
       101814183 BCL2L1; BCL2 like 1
       101818228 BCL2; BCL2, apoptosis regulator
       101813103 quinone oxidoreductase PIG3-like
       101815359 EI24; EI24, autophagy associated transmembrane protein
       101813369 SHISA5; shisa family member 5
       101817073 p53 apoptosis effector related to PMP-22-like
       101816892 p53 apoptosis effector related to PMP-22-like
       101815542 ZMAT3; zinc finger matrin-type 3
       101817349 SIAH1; siah E3 ubiquitin protein ligase 1
       101811954 cytochrome c
       101817511 APAF1; apoptotic peptidase activating factor 1
       101808292 CASP9; caspase 9
       101808212 CASP3; caspase 3
       101815856 AIFM2; apoptosis inducing factor, mitochondria associated 2
       101814335 IGFBP3; insulin like growth factor binding protein 3
       101808710 IGF1; insulin like growth factor 1
       101814159 CD82; CD82 molecule
       101818592 THBS1; thrombospondin 1
       101818637 SERPINB5; serpin family B member 5
       101813959 DDB2; damage specific DNA binding protein 2
       101815464 RRM2; ribonucleotide reductase regulatory subunit M2
       101819545 RRM2B; ribonucleotide reductase regulatory TP53 inducible subunit M2B
       101817772 SESN3; sestrin 3
       101807881 SESN1; sestrin 1
       101808612 sestrin-3-like
       101820249 SESN2; protein FAM76A
       101815785 PTEN; phosphatase and tensin homolog
       101818727 TSC2; tuberous sclerosis 2
       101812249 STEAP3; STEAP3 metalloreductase
       101808738 RFWD2; ring finger and WD repeat domain 2
       101820010 RCHY1; ring finger and CHY zinc finger domain containing 1
       101820555 CCNG1; cyclin G1
       101815914 CCNG2; cyclin G2
       101816784 PPM1D; protein phosphatase, Mg2+/Mn2+ dependent 1D
       101820371 TP73; tumor protein p73
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K19748 GORAB; RAB6-interacting golgin
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K10127 MDM4; protein Mdm4
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K06644 SFN; stratifin
K10128 RPRM; reprimo, TP53-dependent G2 arrest mediator candidate
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K10129 GTSE1; G-2 and S-phase expressed protein 1
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K10130 LRDD; leucine-rich repeats and death domain-containing protein
K04722 TNFRSF10A_B; tumor necrosis factor receptor superfamily member 10A/B
K04722 TNFRSF10A_B; tumor necrosis factor receptor superfamily member 10A/B
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K10131 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
K22744 SIVA1; apoptosis regulatory protein Siva
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator Bcl-2
K10133 TP53I3; tumor protein p53-inducible protein 3 [EC:1.-.-.-]
K10134 EI24; etoposide-induced 2.4 mRNA
K10135 SCOTIN; scotin
K10136 PERP; TP53 apoptosis effector
K10136 PERP; TP53 apoptosis effector
K10137 ZMAT3; zinc finger, matrin type 3
K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K22745 AIFM2; apoptosis-inducing factor 2
K10138 IGFBP3; insulin-like growth factor-binding protein 3
K05459 IGF1; insulin-like growth factor 1
K06509 KAI1; CD82 antigen
K16857 THBS1; thrombospondin 1
K10139 SERPINB5; serpin B5
K10140 DDB2; DNA damage-binding protein 2
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K10141 SESN1_3; sestrin 1/3
K10141 SESN1_3; sestrin 1/3
K10141 SESN1_3; sestrin 1/3
K20394 SESN2; sestrin 2
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K07207 TSC2; tuberous sclerosis 2
K10142 STEAP3; metalloreductase STEAP3 [EC:1.16.1.-]
K10143 RFWD2; E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]
K10144 RCHY1; RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]
K10145 CCNG1; cyclin G1
K10146 CCNG2; cyclin G2
K10147 PPM1D; protein phosphatase 1D [EC:3.1.3.16]
K10148 TP73; tumor protein p73
     04218 Cellular senescence [PATH:fab04218]
       101818496 TGFB1; transforming growth factor beta-1
       101814341 TGFB2; transforming growth factor beta 2
       101809258 TGFB3; transforming growth factor beta 3
       101809241 TGFBR1; transforming growth factor beta receptor 1
       101811048 TGFBR2; transforming growth factor beta receptor 2
       101808986 TGF-beta receptor type-2-like
       101818681 SMAD2; SMAD family member 2
       101806307 SMAD3; SMAD family member 3
       101815251 cyclin-dependent kinase inhibitor 2A-like
       101815443 cyclin-dependent kinase 4 inhibitor B-like
       101815768 CDK6; cyclin dependent kinase 6
       101807319 CCND1; cyclin D1
       101818224 CCND2; cyclin D2
       101819978 CCND3; cyclin D3
       101806985 RB1; RB transcriptional corepressor 1
       101816601 RBL1; RB transcriptional corepressor like 1
       101806783 RBL2; RB transcriptional corepressor like 2
       101808436 E2F1; E2F transcription factor 1
       101805813 E2F2; E2F transcription factor 2
       101815458 E2F3; E2F transcription factor 3
       101806563 E2F4; E2F transcription factor 4
       101817008 E2F5; E2F transcription factor 5
       101811931 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       101821801 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       101814811 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       101820843 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
       101811808 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
       101812251 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
       101809090 FOXO1; forkhead box O1
       101810105 FOXO3; forkhead box O3
       101811025 CDKN1A; cyclin dependent kinase inhibitor 1A
       101821269 CCNE1; cyclin E1
       101809310 CCNE2; cyclin E2
       101808190 class I histocompatibility antigen
       101821968 class I histocompatibility antigen
       101810718 class I histocompatibility antigen
       101809651 KRAS; KRAS proto-oncogene, GTPase
       101813585 NRAS; neuroblastoma RAS viral oncogene homolog
       101816569 RRAS2; related RAS viral (r-ras) oncogene homolog 2
       101818393 MRAS; muscle RAS oncogene homolog
       101811520 HRAS; HRas proto-oncogene, GTPase
       101819472 AKT3; AKT serine/threonine kinase 3
       101814876 AKT1; AKT serine/threonine kinase 1
       101806512 TSC1; tuberous sclerosis 1
       101818727 TSC2; tuberous sclerosis 2
       101820693 MTOR; mechanistic target of rapamycin
       101815785 PTEN; phosphatase and tensin homolog
       101810475 SIRT1; sirtuin 1
       101806462 CCNA1; cyclin A1
       101807947 CCNA2; cyclin A2
       101807278 MYBL2; MYB proto-oncogene like 2
       101805652 LIN9; lin-9 DREAM MuvB core complex component
       101810107 LIN54; lin-54 DREAM MuvB core complex component
       101815679 RBBP4; RB binding protein 4, chromatin remodeling factor
       101818154 FOXM1; forkhead box M1
       101819732 MYC; v-myc avian myelocytomatosis viral oncogene homolog
       101813089 MDM2; MDM2 proto-oncogene
       101819448 RASSF5; Ras association domain family member 5
       101812846 FBXW11; F-box and WD repeat domain containing 11
       101812833 BTRC; beta-transducin repeat containing E3 ubiquitin protein ligase
       101821684 HIPK4; homeodomain interacting protein kinase 4
       101815240 HIPK1; homeodomain interacting protein kinase 1
       101821443 HIPK2; homeodomain interacting protein kinase 2
       101807765 HIPK3; homeodomain interacting protein kinase 3
       107603979 PPP1CC; protein phosphatase 1 catalytic subunit gamma
       101813100 PPP1CB; protein phosphatase 1 catalytic subunit beta
       101810420 PPP1CA; protein phosphatase 1 catalytic subunit alpha
       101816261 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
       101816905 MAP2K1; mitogen-activated protein kinase kinase 1
       101820507 MAP2K2; mitogen-activated protein kinase kinase 2
       101815088 MAPK1; mitogen-activated protein kinase 1
       101811998 ETS1; ETS proto-oncogene 1, transcription factor
       101809415 MAP2K3; mitogen-activated protein kinase kinase 3
       101819388 MAP2K6; mitogen-activated protein kinase kinase 6
       101819980 MAPK14; mitogen-activated protein kinase 14
       101817434 MAPK13; mitogen-activated protein kinase 13
       101807358 MAPK12; mitogen-activated protein kinase 12
       101814783 MAPK11; mitogen-activated protein kinase 11
       101821221 GADD45G; growth arrest and DNA damage inducible gamma
       101821925 CDK1; cyclin dependent kinase 1
       101815219 CCNB2; cyclin B2
       101815007 CCNB3; cyclin B3
       101806043 G2/mitotic-specific cyclin-B3-like
       101816422 MRE11; MRE11 homolog, double strand break repair nuclease
       101817480 RAD50; RAD50 double strand break repair protein
       101810040 NBN; nibrin
       101810210 ATM; ATM serine/threonine kinase
       101811158 CHEK2; checkpoint kinase 2
       101817803 RAD9A; RAD9 checkpoint clamp component A
       101813911 RAD9B; RAD9 checkpoint clamp component B
       101810964 RAD1; RAD1 checkpoint DNA exonuclease
       101806794 HUS1; HUS1 checkpoint clamp component
       101809341 ATR; ATR serine/threonine kinase
       101815748 CHEK1; checkpoint kinase 1
       101816817 CDC25A; cell division cycle 25A
       101807092 SQSTM1; sequestosome 1
       101816505 GATA4; GATA binding protein 4
       101806875 TRAF3IP2; TRAF3 interacting protein 2
       101815528 NFKB1; nuclear factor kappa B subunit 1
       101806545 IL6; interleukin 6
       101808020 interleukin-8-like
       101807822 interleukin-8-like
       101808210 interleukin-8-like
       101814335 IGFBP3; insulin like growth factor binding protein 3
       107603482 ZFP36L2; ZFP36 ring finger protein like 2
       101814668 ZFP36L1; ZFP36 ring finger protein like 1
       101819434 CACNA1D; calcium voltage-gated channel subunit alpha1 D
       101816528 TRPV4; transient receptor potential cation channel subfamily V member 4
       101813566 TRPM7; transient receptor potential cation channel subfamily M member 7
       101816358 CAPN11; calpain 11
       101818353 calpain-1 catalytic subunit-like
       101809391 CAPN2; calpain 2
       101817508 calmodulin
       101813679 CALM2; calmodulin 2
       101808084 CALM1; calmodulin 1
       101818195 CALML4; calmodulin like 4
       101807808 PPP3CC; serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform
       101818111 PPP3CA; protein phosphatase 3 catalytic subunit alpha
       101813689 PPP3CB; protein phosphatase 3 catalytic subunit beta
       101820532 PPP3R1; protein phosphatase 3 regulatory subunit B, alpha
       101811894 NFATC1; nuclear factor of activated T-cells 1
       101811165 NFATC2; nuclear factor of activated T-cells 2
       101811207 NFATC3; nuclear factor of activated T-cells 3
       101816592 ITPR1; inositol 1,4,5-trisphosphate receptor type 1
       101811180 ITPR2; inositol 1,4,5-trisphosphate receptor type 2
       101809694 ITPR3; inositol 1,4,5-trisphosphate receptor type 3
       101818491 SLC25A6; solute carrier family 25 member 6
       101815466 SLC25A5; solute carrier family 25 member 5
       101810172 SLC25A4; solute carrier family 25 member 4
       101809595 PPID; peptidylprolyl isomerase D
       101813252 VDAC1; voltage dependent anion channel 1
       101810113 VDAC2; voltage dependent anion channel 2
       101819191 VDAC3; voltage dependent anion channel 3
       101811915 MCU; mitochondrial calcium uniporter
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04685 CDKN2B; cyclin-dependent kinase inhibitor 2B
K04685 CDKN2B; cyclin-dependent kinase inhibitor 2B
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K06618 RB1; retinoblastoma-associated protein
K04681 RBL1; retinoblastoma-like protein 1
K16332 RBL2; retinoblastoma-like protein 2
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04682 E2F4_5; transcription factor E2F4/5
K04682 E2F4_5; transcription factor E2F4/5
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K07201 FOXO1; forkhead box protein O1
K09408 FOXO3; forkhead box protein O3
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K07830 RRAS2; Ras-related protein R-Ras2
K07831 MRAS; Ras-related protein M-Ras
K02833 HRAS; GTPase HRas
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K11411 SIRT1; NAD+-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K21769 MYBL2; myb-related protein B
K21773 LIN9; protein lin-9
K21776 LIN54; protein lin-54
K10752 RBBP4; histone-binding protein RBBP4
K09406 FOXM; forkhead box protein M
K04377 MYC; Myc proto-oncogene protein
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K08015 RASSF5; Ras association domain-containing protein 5
K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K02678 ETS1; C-ets-1
K04432 MAP2K3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K21771 CCNB3; G2/mitotic-specific cyclin-B3
K21771 CCNB3; G2/mitotic-specific cyclin-B3
K10865 MRE11; double-strand break repair protein MRE11
K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
K10867 NBN; nibrin
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]
K10995 RAD9B; cell cycle checkpoint control protein RAD9B
K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
K10903 HUS1; HUS1 checkpoint protein
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
K14381 SQSTM1; sequestosome 1
K09183 GATA4; GATA-binding protein 4
K21124 TRAF3IP2; adaptor protein CIKS
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K05405 IL6; interleukin 6
K10030 IL8; interleukin 8
K10030 IL8; interleukin 8
K10030 IL8; interleukin 8
K10138 IGFBP3; insulin-like growth factor-binding protein 3
K18753 ZFP36L; butyrate response factor
K18753 ZFP36L; butyrate response factor
K04851 CACNA1D; voltage-dependent calcium channel L type alpha-1D
K04973 TRPV4; transient receptor potential cation channel subfamily V member 4
K04982 TRPM7; transient receptor potential cation channel subfamily M member 7 [EC:2.7.11.1]
K01367 CAPN1; calpain-1 [EC:3.4.22.52]
K01367 CAPN1; calpain-1 [EC:3.4.22.52]
K03853 CAPN2; calpain-2 [EC:3.4.22.53]
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3; nuclear factor of activated T-cells, cytoplasmic 3
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05864 PPID; peptidyl-prolyl isomerase D [EC:5.2.1.8]
K05862 VDAC1; voltage-dependent anion channel protein 1
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K20858 MCU; calcium uniporter protein, mitochondrial
 
   09144 Cellular community - eukaryotes
 
   09145 Cellular community - prokaryotes
 
   09142 Cell motility
 
 09150 Organismal Systems
 
 09160 Human Diseases
 
 09180 Brite Hierarchies
 
 09190 Not Included in Pathway or Brite

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: November 25, 2020