KEGG Orthology (KO) - Felis catus (domestic cat)

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     KO
 09100 Metabolism
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
   09131 Membrane transport
 
   09132 Signal transduction
     02020 Two-component system
     04010 MAPK signaling pathway [PATH:fca04010]
     04013 MAPK signaling pathway - fly
     04016 MAPK signaling pathway - plant
     04011 MAPK signaling pathway - yeast
     04012 ErbB signaling pathway [PATH:fca04012]
     04014 Ras signaling pathway [PATH:fca04014]
       493978 EGF; pro-epidermal growth factor precursor
       101094921 TGFA; protransforming growth factor alpha isoform X1
       101082206 FGF1; fibroblast growth factor 1 isoform X1
       100135772 FGF2; LOW QUALITY PROTEIN: fibroblast growth factor 2
       100136904 FGF5; fibroblast growth factor 5 precursor
       101084335 FGF9; fibroblast growth factor 9
       101090606 FGF17; fibroblast growth factor 17 isoform X1
       101091459 FGF6; fibroblast growth factor 6
       101084778 FGF16; fibroblast growth factor 16
       101097982 FGF7; fibroblast growth factor 7 isoform X1
       101098518 FGF18; fibroblast growth factor 18
       111556546 FGF4; fibroblast growth factor 4
       111556666 FGF3; fibroblast growth factor 3
       101084652 FGF8; fibroblast growth factor 8 isoform X1
       101083745 FGF22; fibroblast growth factor 22
       101090489 FGF10; fibroblast growth factor 10
       101083766 FGF20; fibroblast growth factor 20
       101087099 FGF19; fibroblast growth factor 19
       101080595 FGF21; fibroblast growth factor 21
       101100063 FGF23; fibroblast growth factor 23
       100144611 NGF; beta-nerve growth factor
       493690 BDNF; brain-derived neurotrophic factor precursor
       493963 NTF3; neurotrophin-3 precursor
       101100428 NTF4; neurotrophin-4
       493804 INS; insulin precursor
       101101237 IGF1; insulin-like growth factor I isoform X3
       101093644 IGF2; insulin-like growth factor II isoform X3
       101087287 PDGFA; platelet-derived growth factor subunit A isoform X1
       100135774 PDGFB; platelet-derived growth factor subunit B isoform X4
       101088742 PDGFC; LOW QUALITY PROTEIN: platelet-derived growth factor C
       101084984 PDGFD; platelet-derived growth factor D isoform X1
       101091467 CSF1; macrophage colony-stimulating factor 1 isoform X1
       493937 KITLG; kit ligand precursor
       493796 FLT3LG; fms related tyrosine kinase 3 ligand precursor
       493845 VEGFA; vascular endothelial growth factor A precursor
       101092465 VEGFB; vascular endothelial growth factor B isoform X1
       101095904 PGF; placenta growth factor isoform X2
       493703 VEGFD; vascular endothelial growth factor D
       101085368 VEGFC; vascular endothelial growth factor C
       493705 HGF; hepatocyte growth factor precursor
       101087130 ANGPT1; angiopoietin-1 isoform X1
       102901787 ANGPT2; angiopoietin-2 isoform X1
       101091274 ANGPT4; angiopoietin-4 isoform X1
       101085951 EFNA5; ephrin-A5 isoform X1
       101094570 EFNA1; ephrin-A1 isoform X1
       101094822 EFNA3; ephrin-A3
       111557556 EFNA2; ephrin-A2
       101095077 EFNA4; ephrin-A4 isoform X1
       100510799 EGFR; epidermal growth factor receptor isoform X1
       101086055 FGFR1; fibroblast growth factor receptor 1 isoform X3
       101095198 FGFR2; fibroblast growth factor receptor 2 isoform X6
       100141386 FGFR3; fibroblast growth factor receptor 3 isoform X1
       101100864 FGFR4; fibroblast growth factor receptor 4 isoform X1
       101101519 NGFR; LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 16
       101081603 NTRK1; high affinity nerve growth factor receptor
       101101347 NTRK2; BDNF/NT-3 growth factors receptor isoform X1
       100127108 INSR; insulin receptor isoform X1
       100500937 IGF1R; insulin-like growth factor 1 receptor isoform X1
       101090765 PDGFRA; platelet-derived growth factor receptor alpha
       101084600 PDGFRB; platelet-derived growth factor receptor beta isoform X1
       493706 CSF1R; macrophage colony-stimulating factor 1 receptor precursor
       493766 KIT; mast/stem cell growth factor receptor Kit precursor
       101099264 FLT3; receptor-type tyrosine-protein kinase FLT3
       101088292 FLT1; vascular endothelial growth factor receptor 1 isoform X1
       101094727 FLT4; vascular endothelial growth factor receptor 3 isoform X1
       101090260 KDR; vascular endothelial growth factor receptor 2
       493669 MET; hepatocyte growth factor receptor precursor
       101091977 TEK; angiopoietin-1 receptor isoform X1
       101085481 EPHA2; LOW QUALITY PROTEIN: ephrin type-A receptor 2
       101099916 GRB2; growth factor receptor-bound protein 2 isoform X1
       101088326 GAB1; GRB2-associated-binding protein 1 isoform X4
       101101410 GAB2; GRB2-associated-binding protein 2 isoform X2
       101092911 SHC1; LOW QUALITY PROTEIN: SHC-transforming protein 1
       101083489 SHC2; SHC-transforming protein 2 isoform X1
       101095865 SHC3; SHC-transforming protein 3
       101099050 SHC4; SHC-transforming protein 4
       101085500 PTPN11; tyrosine-protein phosphatase non-receptor type 11 isoform X1
       101098862 SOS1; son of sevenless homolog 1 isoform X1
       101088847 SOS2; LOW QUALITY PROTEIN: son of sevenless homolog 2
       101092925 PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1
       101080675 PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
       101093110 RASGRP1; RAS guanyl-releasing protein 1 isoform X1
       101094450 RASGRP2; RAS guanyl-releasing protein 2 isoform X1
       101085456 RASGRP3; ras guanyl-releasing protein 3 isoform X1
       101094467 RASGRP4; RAS guanyl-releasing protein 4 isoform X1
       111559549 uncharacterized protein LOC111559549
       101097059 tyrosine-protein kinase ZAP-70 isoform X2
       101093319 LAT; linker for activation of T-cells family member 1 isoform X1
       101092146 HTR7; 5-hydroxytryptamine receptor 7 isoform X3
       101086580 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
       101093317 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
       101084799 GNB3; LOW QUALITY PROTEIN: guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
       101091855 GNB4; guanine nucleotide-binding protein subunit beta-4
       101081809 GNB5; guanine nucleotide-binding protein subunit beta-5 isoform X1
       101097491 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
       101091560 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
       101081928 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 isoform X1
       111561761 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
       101088219 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
       101090817 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 isoform X2
       111557526 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
       101088915 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
       101084346 GNG14; putative guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-14
       101089378 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
       101086526 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
       101088476 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
       101096184 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
       101090494 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X3
       101095353 PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X1
       101092941 RASGRF1; ras-specific guanine nucleotide-releasing factor 1 isoform X1
       101091172 RASGRF2; ras-specific guanine nucleotide-releasing factor 2 isoform X1
       101082021 GRIN1; glutamate receptor ionotropic, NMDA 1 isoform X1
       101086110 GRIN2A; glutamate receptor ionotropic, NMDA 2A
       101094356 GRIN2B; glutamate receptor ionotropic, NMDA 2B
       101081534 CALM2; calmodulin-2
       101099307 calmodulin-like protein 3
       102902667 calmodulin-like
       101091063 CALM3; calmodulin-3 isoform X1
       101097703 calmodulin-alpha-like
       101094679 CALM1; calmodulin-1
       111556187 calmodulin-like protein 4
       101086824 CALML6; calmodulin-like protein 6 isoform X1
       101100214 CALML4; calmodulin-like protein 4 isoform X1
       751103 HRAS; GTPase HRas isoform X1
       751104 KRAS; GTPase KRas
       751105 NRAS; GTPase NRas
       101092784 MRAS; ras-related protein M-Ras isoform X2
       101096187 RRAS; ras-related protein R-Ras isoform X1
       101094623 RRAS2; ras-related protein R-Ras2 isoform X2
       101092407 NF1; neurofibromin isoform X1
       101095151 RASA1; ras GTPase-activating protein 1
       101098329 RASA2; ras GTPase-activating protein 2 isoform X1
       101092578 RASA3; ras GTPase-activating protein 3
       101091420 RASA4B; ras GTPase-activating protein 4B isoform X1
       101092938 SYNGAP1; ras/Rap GTPase-activating protein SynGAP isoform X2
       101088621 RASAL1; rasGAP-activating-like protein 1 isoform X1
       101100534 RASAL2; ras GTPase-activating protein nGAP isoform X7
       101090495 RASAL3; RAS protein activator like-3
       101094657 RASSF1; ras association domain-containing protein 1 isoform X3
       101089486 RASSF5; ras association domain-containing protein 5 isoform X1
       101091185 STK4; serine/threonine-protein kinase 4
       101094530 TIAM1; T-lymphoma invasion and metastasis-inducing protein 1 isoform X1
       101101277 RAC1; ras-related C3 botulinum toxin substrate 1 isoform X1
       101096744 RAC2; ras-related C3 botulinum toxin substrate 2 isoform X1
       101080496 RAC3; ras-related C3 botulinum toxin substrate 3 isoform X1
       101087171 PAK1; serine/threonine-protein kinase PAK 1
       101082845 PAK2; serine/threonine-protein kinase PAK 2
       101092248 PAK3; serine/threonine-protein kinase PAK 3 isoform X1
       101098348 PAK4; serine/threonine-protein kinase PAK 4 isoform X1
       101091011 PAK5; serine/threonine-protein kinase PAK 5
       101091201 serine/threonine-protein kinase PAK 6 isoform X2
       101084011 RHOA; transforming protein RhoA
       101094274 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
       101091892 PIK3CB; LOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
       101097413 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
       100271864 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X3
       101093286 PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1
       101093586 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
       101087931 AKT1; RAC-alpha serine/threonine-protein kinase
       101092818 AKT3; RAC-gamma serine/threonine-protein kinase isoform X2
       100499544 AKT2; RAC-beta serine/threonine-protein kinase isoform X1
       101086544 IKBKG; NF-kappa-B essential modulator isoform X1
       101095617 CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1
       100142682 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X2
       100142683 NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1
       101096604 RELA; transcription factor p65
       768269 BAD; bcl2-associated agonist of cell death
       493701 BCL2L1; bcl-2-like protein 1
       101089987 FOXO4; forkhead box protein O4
       493945 FASLG; tumor necrosis factor ligand superfamily member 6
       101081386 AFDN; afadin isoform X1
       101094210 SHOC2; leucine-rich repeat protein SHOC-2
       101096047 RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X2
       101081387 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X2
       101100281 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 isoform X1
       101087614 MAPK1; mitogen-activated protein kinase 1
       101087958 MAPK3; mitogen-activated protein kinase 3
       101101581 ADPRH; ADP-ribosylarginine hydrolase isoform X6
       101091384 group IIE secretory phospholipase A2
       101091639 PLA2G2D; group IID secretory phospholipase A2
       101091884 PLA2G2F; group IIF secretory phospholipase A2
       101083969 PLA2G12B; group XIIB secretory phospholipase A2-like protein isoform X1
       101091796 PLA2G5; calcium-dependent phospholipase A2 isoform X2
       101096267 PLA2G3; group 3 secretory phospholipase A2 isoform X1
       101095522 PLA2G1B; phospholipase A2
       101081105 PLA2G10; group 10 secretory phospholipase A2
       101092035 PLA2G2C; LOW QUALITY PROTEIN: putative inactive group IIC secretory phospholipase A2
       101082828 PLA2G4E; cytosolic phospholipase A2 epsilon isoform X1
       101082033 PLA2G4A; cytosolic phospholipase A2 isoform X1
       101083342 cytosolic phospholipase A2 beta isoform X1
       101082574 PLA2G4F; cytosolic phospholipase A2 zeta isoform X1
       101082829 PLA2G4D; cytosolic phospholipase A2 delta
       101095350 PLA2G6; 85/88 kDa calcium-independent phospholipase A2 isoform X1
       101090719 HRAS-like suppressor 3 isoform X2
       101095156 ELK1; ETS domain-containing protein Elk-1 isoform X1
       101090461 ETS1; protein C-ets-1 isoform X1
       101080565 ETS2; protein C-ets-2
       101082014 BRAP; BRCA1-associated protein
       101092156 KSR1; kinase suppressor of Ras 1 isoform X9
       101091904 KSR2; kinase suppressor of Ras 2
       101088478 RAPGEF5; rap guanine nucleotide exchange factor 5 isoform X1
       101094942 RAP1A; ras-related protein Rap-1A isoform X1
       101095993 RAP1B; LOW QUALITY PROTEIN: ras-related protein Rap-1b
       101090558 RALGDS; ral guanine nucleotide dissociation stimulator isoform X2
       102899245 ral guanine nucleotide dissociation stimulator-like
       101090074 RGL1; ral guanine nucleotide dissociation stimulator-like 1 isoform X1
       111556165 RGL2; LOW QUALITY PROTEIN: ral guanine nucleotide dissociation stimulator-like 2
       101088748 ral guanine nucleotide dissociation stimulator-like 2
       101091003 RALA; ras-related protein Ral-A
       101080471 RALB; ras-related protein Ral-B
       101091310 MAPK8; mitogen-activated protein kinase 8 isoform X1
       101101463 MAPK10; mitogen-activated protein kinase 10 isoform X1
       101084765 MAPK9; mitogen-activated protein kinase 9 isoform X1
       101089188 EXOC2; exocyst complex component 2
       101091955 TBK1; serine/threonine-protein kinase TBK1 isoform X1
       101099543 REL; proto-oncogene c-Rel
       101084052 PLD1; phospholipase D1 isoform X3
       101092214 PLD2; phospholipase D2
       101082017 RALBP1; ralA-binding protein 1
       101094772 CDC42; cell division control protein 42 homolog isoform X1
       101088695 PLCE1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1
       101086433 PRKCA; protein kinase C alpha type isoform X1
       101088970 PRKCB; protein kinase C beta type isoform X3
       101082196 PRKCG; protein kinase C gamma type
       101084059 RIN1; ras and Rab interactor 1
       101087622 ABL1; tyrosine-protein kinase ABL1 isoform X1
       101080757 ABL2; LOW QUALITY PROTEIN: Abelson tyrosine-protein kinase 2
       101099995 RAB5A; ras-related protein Rab-5A
       101093783 RAB5B; ras-related protein Rab-5B
       101094966 RAB5C; ras-related protein Rab-5C
       101093695 ARF6; ADP-ribosylation factor 6
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K02582 NGFB; nerve growth factor, beta
K04355 BDNF; brain-derived neurotrophic factor
K04356 NTF3; neurotrophin 3
K12457 NTF4; neurotrophin 4
K04526 INS; insulin
K05459 IGF1; insulin-like growth factor 1
K13769 IGF2; insulin-like growth factor 2
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K05450 PDGFC_D; platelet derived growth factor C/D
K05453 CSF1; macrophage colony-stimulating factor 1
K05461 KITLG; KIT ligand
K05454 FLT3LG; fms-related tyrosine kinase 3 ligand
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05460 HGF; hepatocyte growth factor
K05465 ANGPT1; angiopoietin 1
K05466 ANGPT2; angiopoietin 2
K05467 ANGPT4; angiopoietin 4
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K02583 NGFR; tumor necrosis factor receptor superfamily member 16
K03176 NTRK1; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K04360 NTRK2; neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]
K04527 INSR; insulin receptor [EC:2.7.10.1]
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05090 CSF1R; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K05091 KIT; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05092 FLT3; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K05096 FLT1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K05097 FLT4; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K05098 KDR; kinase insert domain protein receptor [EC:2.7.10.1]
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K05121 TEK; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
K05103 EPHA2; Eph receptor A2 [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K09593 GAB1; GRB2-associated-binding protein 1
K08091 GAB2; GRB2-associated-binding protein 2
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K07293 PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04350 RASGRP1; RAS guanyl-releasing protein 1
K12361 RASGRP2; RAS guanyl-releasing protein 2
K12362 RASGRP3; RAS guanyl-releasing protein 3
K12363 RASGRP4; RAS guanyl-releasing protein 4
K10785 TRBV; T-cell receptor beta chain V region
K07360 ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
K07362 LAT; linker for activation of T cells
K04163 HTR7; 5-hydroxytryptamine receptor 7
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04349 RASGRF1; Ras-specific guanine nucleotide-releasing factor 1
K12326 RASGRF2; Ras-specific guanine nucleotide-releasing factor 2
K05208 GRIN1; glutamate receptor ionotropic, NMDA 1
K05209 GRIN2A; glutamate receptor ionotropic, NMDA 2A
K05210 GRIN2B; glutamate receptor ionotropic, NMDA 2B
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K07831 MRAS; Ras-related protein M-Ras
K07829 RRAS; Ras-related protein R-Ras
K07830 RRAS2; Ras-related protein R-Ras2
K08052 NF1; neurofibromin 1
K04352 RASA1; Ras GTPase-activating protein 1
K08053 RASA2; Ras GTPase-activating protein 2
K12380 RASA3; Ras GTPase-activating protein 3
K17630 RASA4; Ras GTPase-activating protein 4
K17631 SYNGAP; Ras/Rap GTPase-activating protein SynGAP
K17632 RASAL1; RAS protein activator-like 1
K17633 RASAL2; RAS protein activator-like 2
K17634 RASAL3; RAS protein activator-like 3
K09850 RASSF1; Ras association domain-containing protein 1
K08015 RASSF5; Ras association domain-containing protein 5
K04411 STK4; serine/threonine kinase 4
K05731 TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3; p21-activated kinase 3 [EC:2.7.11.1]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K05736 PAK5; p21-activated kinase 5 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K04513 RHOA; Ras homolog gene family, member A
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K02158 BAD; Bcl-2-antagonist of cell death
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K12358 FOXO4; forkhead box protein O4
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K05702 AF6; afadin
K19613 SHOC2; leucine-rich repeat protein SHOC2
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K13618 PLA1A; phosphatidylserine sn-1 acylhydrolase [EC:3.1.1.111]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K01047 PLA2G; secretory phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16343 PLA2G6; calcium-independent phospholipase A2 [EC:3.1.1.4]
K16817 PLA2G16; HRAS-like suppressor 3 [EC:3.1.1.32 3.1.1.4]
K04375 ELK1; ETS domain-containing protein Elk-1
K02678 ETS1; C-ets-1
K21932 ETS2; C-ets-2
K10632 BRAP; BRCA1-associated protein [EC:2.3.2.27]
K14958 KSR1; kinase suppressor of Ras 1
K18529 KSR2; kinase suppressor of Ras 2 [EC:2.7.11.1]
K08019 RAPGEF5; Rap guanine nucleotide exchange factor 5
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K17635 RGL1; ral guanine nucleotide dissociation stimulator-like 1
K17636 RGL2; ral guanine nucleotide dissociation stimulator-like 2
K17636 RGL2; ral guanine nucleotide dissociation stimulator-like 2
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K17637 EXOC2; exocyst complex component 2
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K09254 REL; c-Rel proto-oncogene protein
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K08773 RALBP1; RalA-binding protein 1
K04393 CDC42; cell division control protein 42
K05860 PLCE; phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K17638 RIN1; Ras and Rab interactor 1
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K08887 ABL2; abelson tyrosine-protein kinase 2 [EC:2.7.10.2]
K07887 RAB5A; Ras-related protein Rab-5A
K07888 RAB5B; Ras-related protein Rab-5B
K07889 RAB5C; Ras-related protein Rab-5C
K07941 ARF6; ADP-ribosylation factor 6
     04015 Rap1 signaling pathway [PATH:fca04015]
     04310 Wnt signaling pathway [PATH:fca04310]
     04330 Notch signaling pathway [PATH:fca04330]
     04340 Hedgehog signaling pathway [PATH:fca04340]
     04341 Hedgehog signaling pathway - fly
     04350 TGF-beta signaling pathway [PATH:fca04350]
     04390 Hippo signaling pathway [PATH:fca04390]
       101088123 CRB2; protein crumbs homolog 2 isoform X1
       101092328 CRB1; LOW QUALITY PROTEIN: protein crumbs homolog 1
       101100223 PARD3; partitioning defective 3 homolog isoform X1
       101101605 PARD6A; partitioning defective 6 homolog alpha isoform X1
       105261071 PARD6G; partitioning defective 6 homolog gamma
       101081032 PARD6B; partitioning defective 6 homolog beta
       101087851 PRKCZ; protein kinase C zeta type isoform X2
       101087000 PRKCI; protein kinase C iota type
       101098731 PATJ; LOW QUALITY PROTEIN: inaD-like protein
       101090946 MPP5; MAGUK p55 subfamily member 5
       101096706 AMOT; LOW QUALITY PROTEIN: angiomotin
       101101408 YAP1; LOW QUALITY PROTEIN: transcriptional coactivator YAP1
       101100243 WWTR1; WW domain-containing transcription regulator protein 1
       101095391 CDH1; cadherin-1
       101082110 WTIP; Wilms tumor protein 1-interacting protein
       101092500 LIMD1; LIM domain-containing protein 1 isoform X1
       101092118 AJUBA; LIM domain-containing protein ajuba
       101087787 NF2; merlin isoform X3
       101092738 WWC1; protein KIBRA isoform X1
       101081897 FRMD1; FERM domain-containing protein 1 isoform X6
       101097070 FRMD6; FERM domain-containing protein 6 isoform X4
       101096154 SAV1; protein salvador homolog 1
       101081440 STK3; serine/threonine-protein kinase 3 isoform X1
       101081541 RASSF6; ras association domain-containing protein 6 isoform X1
       101094657 RASSF1; ras association domain-containing protein 1 isoform X3
       101099271 PPP2CA; serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
       101094667 PPP2CB; serine/threonine-protein phosphatase 2A catalytic subunit beta isoform
       101083726 PPP2R1A; serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
       101081075 PPP2R1B; serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X1
       101086093 PPP2R2D; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform
       101099546 PPP2R2A; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform isoform X1
       101084083 PPP2R2B; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform isoform X1
       101091784 PPP2R2C; protein phosphatase 2, regulatory subunit B, gamma isoform X2
       101081470 LATS1; serine/threonine-protein kinase LATS1 isoform X1
       101093824 LATS2; serine/threonine-protein kinase LATS2 isoform X1
       101099872 MOB1A; MOB kinase activator 1A isoform X1
       101084106 MOB1B; MOB kinase activator 1B isoform X1
       101100922 PPP1CC; serine/threonine-protein phosphatase PP1-gamma catalytic subunit
       101092932 PPP1CB; serine/threonine-protein phosphatase PP1-beta catalytic subunit
       109492306 PPP1CA; serine/threonine-protein phosphatase PP1-alpha catalytic subunit
       101083477 TP53BP2; apoptosis-stimulating of p53 protein 2 isoform X3
       101086763 LLGL1; lethal(2) giant larvae protein homolog 1 isoform X1
       101100607 LLGL2; lethal(2) giant larvae protein homolog 2 isoform X1
       101092000 SCRIB; protein scribble homolog isoform X1
       101084051 DLG1; disks large homolog 1 isoform X4
       101097912 DLG2; disks large homolog 2 isoform X17
       101088910 DLG3; disks large homolog 3 isoform X5
       101093902 DLG4; disks large homolog 4 isoform X10
       101093803 DLG5; disks large homolog 5 isoform X1
       101091915 CSNK1D; casein kinase I isoform X2
       101101321 casein kinase I isoform X1
       101094156 FBXW11; F-box/WD repeat-containing protein 11 isoform X4
       101097596 BTRC; F-box/WD repeat-containing protein 1A isoform X1
       101088009 TP73; tumor protein p73 isoform X1
       111558033 BBC3; bcl-2-binding component 3
       101098180 TEAD2; transcriptional enhancer factor TEF-4 isoform X1
       101089948 TEAD4; transcriptional enhancer factor TEF-3 isoform X1
       101093890 TEAD1; transcriptional enhancer factor TEF-1 isoform X1
       101090266 TEAD3; transcriptional enhancer factor TEF-5
       101094598 CTGF; connective tissue growth factor
       101101401 GLI2; zinc finger protein GLI2
       101081041 AREG; amphiregulin
       493835 BIRC5; baculoviral IAP repeat-containing protein 5
       101082056 AFP; alpha-fetoprotein
       101095098 alpha-fetoprotein-like isoform X1
       101087258 ITGB2; integrin beta-2
       101082206 FGF1; fibroblast growth factor 1 isoform X1
       768263 TGFB1; transforming growth factor beta-1 isoform X2
       101093414 TGFB2; transforming growth factor beta-2 isoform X2
       101098469 TGFB3; transforming growth factor beta-3 isoform X1
       101094057 TGFBR1; TGF-beta receptor type-1 isoform X1
       101091725 TGFBR2; TGF-beta receptor type-2
       101088277 SMAD7; mothers against decapentaplegic homolog 7 isoform X1
       101087179 SMAD2; mothers against decapentaplegic homolog 2 isoform X1
       101101387 SMAD3; mothers against decapentaplegic homolog 3
       101093650 SMAD4; mothers against decapentaplegic homolog 4 isoform X1
       100127105 SERPINE1; plasminogen activator inhibitor 1
       100301987 BMP2; bone morphogenetic protein 2
       101100311 BMP4; bone morphogenetic protein 4 isoform X2
       101097318 BMP5; bone morphogenetic protein 5
       101098870 BMP6; bone morphogenetic protein 6
       101094168 BMP7; LOW QUALITY PROTEIN: bone morphogenetic protein 7
       111559734 bone morphogenetic protein 7-like
       101089375 BMP8A; LOW QUALITY PROTEIN: bone morphogenetic protein 8A
       102901566 BMP8B; bone morphogenetic protein 8B isoform X1
       101081533 GDF5; growth/differentiation factor 5 isoform X1
       111558542 GDF6; growth/differentiation factor 6
       111559870 GDF7; growth/differentiation factor 7
       101080263 AMH; muellerian-inhibiting factor
       101089548 BMPR1A; bone morphogenetic protein receptor type-1A
       101082489 BMPR1B; bone morphogenetic protein receptor type-1B isoform X3
       101096338 BMPR2; bone morphogenetic protein receptor type-2
       101085713 SMAD1; mothers against decapentaplegic homolog 1
       101097058 ID1; DNA-binding protein inhibitor ID-1
       101090256 ID2; DNA-binding protein inhibitor ID-2
       101094190 WNT1; proto-oncogene Wnt-1
       493672 WNT2; protein Wnt-2 precursor
       101080904 WNT2B; protein Wnt-2b
       101088533 WNT3; proto-oncogene Wnt-3
       101080607 WNT3A; protein Wnt-3a
       101095185 WNT4; protein Wnt-4 isoform X1
       101085809 WNT5B; protein Wnt-5b
       101080694 WNT5A; protein Wnt-5a isoform X1
       101099392 WNT6; protein Wnt-6
       101083664 WNT7A; protein Wnt-7a
       101095592 WNT7B; protein Wnt-7b isoform X1
       101089489 WNT8A; protein Wnt-8a
       101096357 WNT8B; protein Wnt-8b
       101080844 WNT9B; LOW QUALITY PROTEIN: protein Wnt-9b
       111560436 WNT9A; protein Wnt-9a isoform X1
       101092455 WNT10A; protein Wnt-10a
       101093948 WNT10B; protein Wnt-10b
       101100080 WNT11; protein Wnt-11
       101090252 WNT16; protein Wnt-16
       101082735 FZD1; frizzled-1
       101087255 FZD7; frizzled-7
       101085253 FZD2; frizzled-2
       101095250 FZD3; frizzled-3 isoform X1
       101093710 FZD4; frizzled-4 isoform X1
       101101229 FZD8; frizzled-8
       101097508 FZD5; frizzled-5
       101101443 FZD6; frizzled-6
       101087697 FZD9; frizzled-9
       101081169 FZD10; frizzled-10
       101094385 DVL2; segment polarity protein dishevelled homolog DVL-2 isoform X1
       101084782 DVL1; segment polarity protein dishevelled homolog DVL-1 isoform X1
       101095675 DVL3; segment polarity protein dishevelled homolog DVL-3 isoform X2
       101088481 YWHAQ; 14-3-3 protein theta
       100127113 YWHAZ; 14-3-3 protein zeta/delta
       101091685 YWHAB; 14-3-3 protein beta/alpha
       101101425 YWHAE; 14-3-3 protein epsilon isoform X1
       101084156 YWHAG; 14-3-3 protein gamma
       101099908 YWHAH; 14-3-3 protein eta
       101081660 GSK3B; glycogen synthase kinase-3 beta isoform X2
       101097342 CTNNB1; catenin beta-1 isoform X1
       101096138 APC; adenomatous polyposis coli protein isoform X5
       101097211 APC2; adenomatous polyposis coli protein 2 isoform X1
       101088804 AXIN1; axin-1 isoform X1
       101093061 AXIN2; axin-2 isoform X1
       101081447 NKD2; protein naked cuticle homolog 2
       101096624 NKD1; protein naked cuticle homolog 1 isoform X1
       101098768 TCF7; transcription factor 7 isoform X1
       101089850 TCF7L1; transcription factor 7-like 1 isoform X1
       101095618 TCF7L2; transcription factor 7-like 2 isoform X1
       101088077 LEF1; lymphoid enhancer-binding factor 1 isoform X2
       100379628 MYC; myc proto-oncogene protein
       100037407 CCND1; G1/S-specific cyclin-D1
       101090950 CCND2; G1/S-specific cyclin-D2
       101101311 CCND3; G1/S-specific cyclin-D3 isoform X1
       100379629 SOX2; transcription factor SOX-2
       101090987 SNAI2; zinc finger protein SNAI2 isoform X1
       101083444 baculoviral IAP repeat-containing protein 3
       101101663 BIRC2; baculoviral IAP repeat-containing protein 2
       100144392 ACTG1; actin, cytoplasmic 2
       101098507 ACTB; actin, cytoplasmic 1
       101089324 CTNNA1; catenin alpha-1
       101088568 CTNNA2; catenin alpha-2 isoform X1
       101086346 CTNNA3; catenin alpha-3
K16681 CRB; protein crumbs
K16681 CRB; protein crumbs
K04237 PARD3; partitioning defective protein 3
K06093 PARD6; partitioning defective protein 6
K06093 PARD6; partitioning defective protein 6
K06093 PARD6; partitioning defective protein 6
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K06069 PRKCI; atypical protein kinase C iota type [EC:2.7.11.13]
K06092 INADL; InaD-like protein
K06091 MPP5; MAGUK p55 subfamily member 5
K16819 AMOT; angiomotin
K16687 YAP1; transcriptional coactivator YAP1
K16820 WWTR1; WW domain-containing transcription regulator protein 1
K05689 CDH1; cadherin 1, type 1, E-cadherin
K16682 AJUBA; LIM domain-containing protein
K16682 AJUBA; LIM domain-containing protein
K16682 AJUBA; LIM domain-containing protein
K16684 NF2; merlin
K16685 WWC1; protein KIBRA
K16821 FRMD1; FERM domain-containing protein 1
K16822 FRMD6; FERM domain-containing protein 6
K16686 SAV1; scaffold protein salvador
K04412 STK3; serine/threonine kinase 3
K09854 RASSF6; Ras association domain-containing protein 6
K09850 RASSF1; Ras association domain-containing protein 1
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K08791 LATS1_2; serine/threonine-protein kinase LATS1/2 [EC:2.7.11.1]
K08791 LATS1_2; serine/threonine-protein kinase LATS1/2 [EC:2.7.11.1]
K06685 MOB1; MOB kinase activator 1
K06685 MOB1; MOB kinase activator 1
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K16823 TP53BP2; apoptosis-stimulating of p53 protein 2
K06094 LLGL; lethal(2) giant larvae protein
K06094 LLGL; lethal(2) giant larvae protein
K16175 SCRIB; protein scribble
K12076 DLG1; disks large protein 1
K12075 DLG2; discs large protein 2
K21098 DLG3; discs large protein 3
K11828 DLG4; discs large protein 4
K24050 DLG5; discs large protein 5
K08959 CSNK1D; casein kinase 1, delta [EC:2.7.11.1]
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
K10148 TP73; tumor protein p73
K10132 BBC3; Bcl-2-binding component 3
K09448 TEAD; transcriptional enhancer factor
K09448 TEAD; transcriptional enhancer factor
K09448 TEAD; transcriptional enhancer factor
K09448 TEAD; transcriptional enhancer factor
K06827 CTGF; connective tissue growth factor (insulin-like growth factor-binding protein 8)
K16798 GLI2; zinc finger protein GLI2
K09782 AREG; amphiregulin
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K16144 AFP; alpha-fetoprotein
K16144 AFP; alpha-fetoprotein
K06464 ITGB2; integrin beta 2
K18496 FGF1; fibroblast growth factor 1
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K19631 SMAD7; mothers against decapentaplegic homolog 7
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K03982 SERPINE1; plasminogen activator inhibitor 1
K21283 BMP2; bone morphogenetic protein 2
K04662 BMP4; bone morphogenetic protein 4
K04663 BMP5; bone morphogenetic protein 5
K16620 BMP6; bone morphogenetic protein 6
K16621 BMP7; bone morphogenetic protein 7
K16621 BMP7; bone morphogenetic protein 7
K16622 BMP8; bone morphogenetic protein 8
K16622 BMP8; bone morphogenetic protein 8
K04664 GDF5; growth differentiation factor 5
K20012 GDF6; growth differentiation factor 6
K20013 GDF7; growth differentiation factor 7
K04665 AMH; anti-mullerian hormone
K04673 BMPR1A; bone morphogenetic protein receptor type-1A [EC:2.7.11.30]
K13578 BMPR1B; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]
K04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
K04676 SMAD1; mothers against decapentaplegic homolog 1
K04680 ID1; DNA-binding protein inhibitor ID1
K17693 ID2; DNA-binding protein inhibitor ID2
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K02842 FZD9_10; frizzled 9/10
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K06630 YWHAE; 14-3-3 protein epsilon
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02105 CTNNB1; catenin beta 1
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K03213 NKD; naked cuticle
K03213 NKD; naked cuticle
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K16796 SOX2; transcription factor SOX2 (SOX group B)
K05706 SNAI2; snail 2
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K05692 ACTB_G1; actin beta/gamma 1
K05692 ACTB_G1; actin beta/gamma 1
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
     04391 Hippo signaling pathway - fly
     04392 Hippo signaling pathway - multiple species [PATH:fca04392]
       101100127 DCHS2; protocadherin-23
       101093545 DCHS1; LOW QUALITY PROTEIN: protocadherin-16
       111559083 LOW QUALITY PROTEIN: protocadherin-16-like
       101085714 FAT4; protocadherin Fat 4
       101101321 casein kinase I isoform X1
       101087787 NF2; merlin isoform X3
       101092738 WWC1; protein KIBRA isoform X1
       101081897 FRMD1; FERM domain-containing protein 1 isoform X6
       101097070 FRMD6; FERM domain-containing protein 6 isoform X4
       101094657 RASSF1; ras association domain-containing protein 1 isoform X3
       101081541 RASSF6; ras association domain-containing protein 6 isoform X1
       101081440 STK3; serine/threonine-protein kinase 3 isoform X1
       101096154 SAV1; protein salvador homolog 1
       101081470 LATS1; serine/threonine-protein kinase LATS1 isoform X1
       101093824 LATS2; serine/threonine-protein kinase LATS2 isoform X1
       101099872 MOB1A; MOB kinase activator 1A isoform X1
       101084106 MOB1B; MOB kinase activator 1B isoform X1
       101082110 WTIP; Wilms tumor protein 1-interacting protein
       101092500 LIMD1; LIM domain-containing protein 1 isoform X1
       101092118 AJUBA; LIM domain-containing protein ajuba
       101101408 YAP1; LOW QUALITY PROTEIN: transcriptional coactivator YAP1
       101100243 WWTR1; WW domain-containing transcription regulator protein 1
       101098180 TEAD2; transcriptional enhancer factor TEF-4 isoform X1
       101089948 TEAD4; transcriptional enhancer factor TEF-3 isoform X1
       101093890 TEAD1; transcriptional enhancer factor TEF-1 isoform X1
       101090266 TEAD3; transcriptional enhancer factor TEF-5
       101101378 RASSF2; ras association domain-containing protein 2
       101098746 RASSF4; ras association domain-containing protein 4 isoform X1
       101087171 PAK1; serine/threonine-protein kinase PAK 1
K16507 DCHS1_2; protocadherin-16/23
K16507 DCHS1_2; protocadherin-16/23
K16507 DCHS1_2; protocadherin-16/23
K16669 FAT4; protocadherin Fat 4
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K16684 NF2; merlin
K16685 WWC1; protein KIBRA
K16821 FRMD1; FERM domain-containing protein 1
K16822 FRMD6; FERM domain-containing protein 6
K09850 RASSF1; Ras association domain-containing protein 1
K09854 RASSF6; Ras association domain-containing protein 6
K04412 STK3; serine/threonine kinase 3
K16686 SAV1; scaffold protein salvador
K08791 LATS1_2; serine/threonine-protein kinase LATS1/2 [EC:2.7.11.1]
K08791 LATS1_2; serine/threonine-protein kinase LATS1/2 [EC:2.7.11.1]
K06685 MOB1; MOB kinase activator 1
K06685 MOB1; MOB kinase activator 1
K16682 AJUBA; LIM domain-containing protein
K16682 AJUBA; LIM domain-containing protein
K16682 AJUBA; LIM domain-containing protein
K16687 YAP1; transcriptional coactivator YAP1
K16820 WWTR1; WW domain-containing transcription regulator protein 1
K09448 TEAD; transcriptional enhancer factor
K09448 TEAD; transcriptional enhancer factor
K09448 TEAD; transcriptional enhancer factor
K09448 TEAD; transcriptional enhancer factor
K09851 RASSF2_4; Ras association domain-containing protein 2/4
K09851 RASSF2_4; Ras association domain-containing protein 2/4
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
     04370 VEGF signaling pathway [PATH:fca04370]
     04371 Apelin signaling pathway [PATH:fca04371]
     04630 JAK-STAT signaling pathway [PATH:fca04630]
     04064 NF-kappa B signaling pathway [PATH:fca04064]
     04668 TNF signaling pathway [PATH:fca04668]
     04066 HIF-1 signaling pathway [PATH:fca04066]
     04068 FoxO signaling pathway [PATH:fca04068]
     04020 Calcium signaling pathway [PATH:fca04020]
     04070 Phosphatidylinositol signaling system [PATH:fca04070]
     04072 Phospholipase D signaling pathway [PATH:fca04072]
     04071 Sphingolipid signaling pathway [PATH:fca04071]
     04024 cAMP signaling pathway [PATH:fca04024]
     04022 cGMP-PKG signaling pathway [PATH:fca04022]
     04151 PI3K-Akt signaling pathway [PATH:fca04151]
     04152 AMPK signaling pathway [PATH:fca04152]
     04150 mTOR signaling pathway [PATH:fca04150]
     04075 Plant hormone signal transduction
 
   09133 Signaling molecules and interaction
 
 09140 Cellular Processes
 
 09150 Organismal Systems
 
 09160 Human Diseases
 
   09161 Cancer: overview
     05200 Pathways in cancer [PATH:fca05200]
       101098832 DCC; LOW QUALITY PROTEIN: netrin receptor DCC
       493932 CASP3; caspase-3
       768260 CASP9; caspase-9 isoform X1
       101096960 APPL1; DCC-interacting protein 13-alpha isoform X1
       101095391 CDH1; cadherin-1
       101097342 CTNNB1; catenin beta-1 isoform X1
       101089324 CTNNA1; catenin alpha-1
       101088568 CTNNA2; catenin alpha-2 isoform X1
       101086346 CTNNA3; catenin alpha-3
       101088804 AXIN1; axin-1 isoform X1
       101093061 AXIN2; axin-2 isoform X1
       101096138 APC; adenomatous polyposis coli protein isoform X5
       101097211 APC2; adenomatous polyposis coli protein 2 isoform X1
       101081660 GSK3B; glycogen synthase kinase-3 beta isoform X2
       101098768 TCF7; transcription factor 7 isoform X1
       101089850 TCF7L1; transcription factor 7-like 1 isoform X1
       101095618 TCF7L2; transcription factor 7-like 2 isoform X1
       101088077 LEF1; lymphoid enhancer-binding factor 1 isoform X2
       493835 BIRC5; baculoviral IAP repeat-containing protein 5
       100379628 MYC; myc proto-oncogene protein
       100037407 CCND1; G1/S-specific cyclin-D1
       101094190 WNT1; proto-oncogene Wnt-1
       493672 WNT2; protein Wnt-2 precursor
       101080904 WNT2B; protein Wnt-2b
       101088533 WNT3; proto-oncogene Wnt-3
       101080607 WNT3A; protein Wnt-3a
       101095185 WNT4; protein Wnt-4 isoform X1
       101085809 WNT5B; protein Wnt-5b
       101080694 WNT5A; protein Wnt-5a isoform X1
       101099392 WNT6; protein Wnt-6
       101083664 WNT7A; protein Wnt-7a
       101095592 WNT7B; protein Wnt-7b isoform X1
       101089489 WNT8A; protein Wnt-8a
       101096357 WNT8B; protein Wnt-8b
       101080844 WNT9B; LOW QUALITY PROTEIN: protein Wnt-9b
       111560436 WNT9A; protein Wnt-9a isoform X1
       101092455 WNT10A; protein Wnt-10a
       101093948 WNT10B; protein Wnt-10b
       101100080 WNT11; protein Wnt-11
       101090252 WNT16; protein Wnt-16
       101082735 FZD1; frizzled-1
       101087255 FZD7; frizzled-7
       101085253 FZD2; frizzled-2
       101095250 FZD3; frizzled-3 isoform X1
       101093710 FZD4; frizzled-4 isoform X1
       101101229 FZD8; frizzled-8
       101097508 FZD5; frizzled-5
       101101443 FZD6; frizzled-6
       101087697 FZD9; frizzled-9
       101081169 FZD10; frizzled-10
       101084481 LRP5; low-density lipoprotein receptor-related protein 5
       101082246 LRP6; low-density lipoprotein receptor-related protein 6
       101094385 DVL2; segment polarity protein dishevelled homolog DVL-2 isoform X1
       101084782 DVL1; segment polarity protein dishevelled homolog DVL-1 isoform X1
       101095675 DVL3; segment polarity protein dishevelled homolog DVL-3 isoform X2
       101087686 FRAT1; proto-oncogene FRAT1
       105261037 FRAT2; GSK-3-binding protein FRAT2
       101090463 F2; prothrombin
       101093714 AGT; angiotensinogen
       101100861 F2R; proteinase-activated receptor 1
       101081027 F2RL3; proteinase-activated receptor 4 isoform X1
       101092556 LPAR1; lysophosphatidic acid receptor 1
       101100950 LPAR2; lysophosphatidic acid receptor 2
       101097996 LPAR3; lysophosphatidic acid receptor 3
       101087973 LPAR4; lysophosphatidic acid receptor 4
       102899848 LPAR5; lysophosphatidic acid receptor 5
       101095629 LPAR6; lysophosphatidic acid receptor 6
       101082936 AGTR1; type-1 angiotensin II receptor
       101093316 GNA12; guanine nucleotide-binding protein subunit alpha-12
       101087625 GNA13; guanine nucleotide-binding protein subunit alpha-13
       101085657 ARHGEF12; rho guanine nucleotide exchange factor 12 isoform X1
       101080861 ARHGEF11; rho guanine nucleotide exchange factor 11 isoform X1
       101083892 ARHGEF1; rho guanine nucleotide exchange factor 1 isoform X1
       101094361 PLEKHG5; pleckstrin homology domain-containing family G member 5 isoform X1
       101084011 RHOA; transforming protein RhoA
       101092552 ROCK1; rho-associated protein kinase 1 isoform X1
       101094501 ROCK2; rho-associated protein kinase 2 isoform X1
       493806 CXCL12; stromal cell-derived factor 1 precursor
       493676 CXCR4; C-X-C chemokine receptor type 4
       101092837 GNAI1; guanine nucleotide-binding protein G(i) subunit alpha-1 isoform X1
       101100320 GNAI3; guanine nucleotide-binding protein G(k) subunit alpha
       101089679 GNAI2; guanine nucleotide-binding protein G(i) subunit alpha-2
       101097794 PTGER1; LOW QUALITY PROTEIN: prostaglandin E2 receptor EP1 subtype
       100169967 PTGER2; prostaglandin E2 receptor EP2 subtype
       101083952 PTGER3; LOW QUALITY PROTEIN: prostaglandin E2 receptor EP3 subtype
       100169968 PTGER4; prostaglandin E2 receptor EP4 subtype
       101098453 LOW QUALITY PROTEIN: guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas
       102900772 neuroendocrine secretory protein 55
       101101375 ADCY1; adenylate cyclase type 1
       101094327 ADCY2; adenylate cyclase type 2 isoform X1
       101088157 ADCY3; adenylate cyclase type 3 isoform X1
       101097735 ADCY4; adenylate cyclase type 4
       101100749 ADCY5; adenylate cyclase type 5 isoform X2
       101091211 ADCY6; adenylate cyclase type 6 isoform X2
       101094148 ADCY7; adenylate cyclase type 7 isoform X1
       101087555 ADCY8; adenylate cyclase type 8 isoform X1
       101095942 ADCY9; adenylate cyclase type 9
       101090494 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X3
       101095353 PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X1
       101086580 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
       101093317 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
       101084799 GNB3; LOW QUALITY PROTEIN: guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
       101091855 GNB4; guanine nucleotide-binding protein subunit beta-4
       101081809 GNB5; guanine nucleotide-binding protein subunit beta-5 isoform X1
       101097491 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
       101091560 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
       101081928 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 isoform X1
       111561761 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
       101088219 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
       101090817 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 isoform X2
       111557526 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
       101088915 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
       101084346 GNG14; putative guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-14
       101089378 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
       101086526 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
       101088476 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
       101096184 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
       101089498 COL4A6; collagen alpha-6(IV) chain isoform X1
       101093002 COL4A5; collagen alpha-5(IV) chain isoform X4
       101096282 COL4A2; collagen alpha-2(IV) chain
       101096030 COL4A1; collagen alpha-1(IV) chain
       101087512 COL4A3; collagen alpha-3(IV) chain isoform X1
       101091469 COL4A4; LOW QUALITY PROTEIN: collagen alpha-4(IV) chain
       101083299 LAMA1; laminin subunit alpha-1 isoform X2
       101092612 LAMA2; LOW QUALITY PROTEIN: laminin subunit alpha-2
       101100161 LAMA3; laminin subunit alpha-3 isoform X5
       101083923 LAMA5; LOW QUALITY PROTEIN: laminin subunit alpha-5
       101086907 LAMA4; laminin subunit alpha-4 isoform X2
       101080367 LAMB1; laminin subunit beta-1
       101082047 LAMB2; laminin subunit beta-2 isoform X1
       101088641 LAMB3; laminin subunit beta-3
       101101552 LAMB4; laminin subunit beta-4 isoform X1
       101090321 LAMC1; laminin subunit gamma-1
       101089571 LAMC2; laminin subunit gamma-2
       101098499 LAMC3; LOW QUALITY PROTEIN: laminin subunit gamma-3
       101081746 FN1; fibronectin isoform X1
       101090237 ITGA2; integrin alpha-2
       101100930 ITGA2B; integrin alpha-IIb
       101093156 ITGA3; integrin alpha-3 isoform X2
       101092454 ITGA6; LOW QUALITY PROTEIN: integrin alpha-6
       101085820 ITGAV; LOW QUALITY PROTEIN: integrin alpha-V
       751821 ITGB1; integrin beta-1 precursor
       101095952 PTK2; focal adhesion kinase 1 isoform X1
       101094274 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
       101091892 PIK3CB; LOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
       101097413 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
       100271864 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X3
       101093286 PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1
       101093586 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
       101091813 PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1
       105260486 NKX3-1; homeobox protein Nkx-3.1
       101087931 AKT1; RAC-alpha serine/threonine-protein kinase
       101092818 AKT3; RAC-gamma serine/threonine-protein kinase isoform X2
       100499544 AKT2; RAC-beta serine/threonine-protein kinase isoform X1
       101095617 CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1
       100142682 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X2
       101086544 IKBKG; NF-kappa-B essential modulator isoform X1
       101090622 NFKBIA; NF-kappa-B inhibitor alpha
       100142683 NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1
       101080578 NFKB2; nuclear factor NF-kappa-B p100 subunit isoform X1
       101096604 RELA; transcription factor p65
       100126581 PTGS2; prostaglandin G/H synthase 2 precursor
       101087020 NOS2; nitric oxide synthase, inducible isoform X2
       493934 BCL2; apoptosis regulator Bcl-2
       101083444 baculoviral IAP repeat-containing protein 3
       101101663 BIRC2; baculoviral IAP repeat-containing protein 2
       101090594 XIAP; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase XIAP
       101080371 BIRC7; baculoviral IAP repeat-containing protein 7 isoform X1
       493701 BCL2L1; bcl-2-like protein 1
       101087620 TRAF1; TNF receptor-associated factor 1 isoform X1
       101096363 TRAF2; TNF receptor-associated factor 2 isoform X1
       101096739 TRAF3; TNF receptor-associated factor 3 isoform X1
       101096365 TRAF4; TNF receptor-associated factor 4
       101086032 TRAF5; TNF receptor-associated factor 5 isoform X1
       101099750 TRAF6; TNF receptor-associated factor 6
       101098152 MTOR; serine/threonine-protein kinase mTOR isoform X1
       101091812 RPS6KB2; ribosomal protein S6 kinase beta-2 isoform X3
       101092561 RPS6KB1; ribosomal protein S6 kinase beta-1 isoform X1
       768269 BAD; bcl2-associated agonist of cell death
       101096628 FOXO1; forkhead box protein O1
       493939 MDM2; E3 ubiquitin-protein ligase Mdm2
       493847 TP53; cellular tumor antigen p53
       493958 CDKN1B; cyclin-dependent kinase inhibitor 1B
       493943 CDKN1A; cyclin-dependent kinase inhibitor 1
       101101671 BCR; breakpoint cluster region protein isoform X1
       101087622 ABL1; tyrosine-protein kinase ABL1 isoform X1
       101084908 CRKL; crk-like protein
       101086100 CRK; adapter molecule crk isoform X1
       101096508 E3 ubiquitin-protein ligase CBL
       101090913 signal transducer and activator of transcription 5A isoform X1
       101090663 STAT5B; LOW QUALITY PROTEIN: signal transducer and activator of transcription 5B
       493888 PIM1; serine/threonine-protein kinase pim-1
       101098037 PIM2; serine/threonine-protein kinase pim-2
       101099143 kininogen-1 isoform X1
       494214 EDN1; endothelin-1 precursor
       101082667 B2 bradykinin receptor isoform X1
       101083419 EDNRA; endothelin-1 receptor
       101086531 EDNRB; endothelin receptor type B
       101094708 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha isoform X2
       101086541 GNA11; guanine nucleotide-binding protein subunit alpha-11
       101090942 PLCB2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X1
       101092961 PLCB3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X1
       101092262 PLCB1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1
       101090005 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1
       101086433 PRKCA; protein kinase C alpha type isoform X1
       101088970 PRKCB; protein kinase C beta type isoform X3
       101082196 PRKCG; protein kinase C gamma type
       751114 IL2; interleukin-2 precursor
       111560806 interleukin-3-like
       751514 IL4; interleukin-4 precursor
       493803 IL5; interleukin-5 precursor
       493687 IL6; interleukin-6 precursor
       101084597 IL7; interleukin-7 isoform X1
       493741 IL12A; interleukin-12 subunit alpha precursor
       768273 IL12B; interleukin-12 subunit beta precursor
       101084678 IL13; interleukin-13 isoform X2
       493682 IL15; interleukin-15 precursor
       654423 IL23A; interleukin-23 subunit alpha
       493801 EPO; erythropoietin precursor
       493648 IFNA8; interferon alpha-8 precursor
       493653 IFNA7; interferon alpha precursor
       101088440 interferon alpha-2-like
       101081371 interferon alpha-like
       493840 IFNA5; LOW QUALITY PROTEIN: interferon alpha-5
       111557596 interferon alpha-like
       493965 IFNG; interferon gamma precursor
       493953 IL2RA; interleukin-2 receptor subunit alpha precursor
       101092622 IL2RB; interleukin-2 receptor subunit beta isoform X1
       101090239 IL2RG; cytokine receptor common subunit gamma
       105261394 IL3RA; interleukin-3 receptor subunit alpha isoform X1
       101096277 IL4R; interleukin-4 receptor subunit alpha
       101091636 CSF2RB; cytokine receptor common subunit beta
       101099031 IL5RA; interleukin-5 receptor subunit alpha isoform X1
       101085689 IL6R; interleukin-6 receptor subunit alpha isoform X1
       101089832 IL6ST; interleukin-6 receptor subunit beta isoform X1
       101100697 IL7R; interleukin-7 receptor subunit alpha
       101093085 IL12RB1; LOW QUALITY PROTEIN: interleukin-12 receptor subunit beta-1
       101088012 IL12RB2; interleukin-12 receptor subunit beta-2 isoform X1
       101091351 IL13RA1; interleukin-13 receptor subunit alpha-1
       101082243 IL15RA; interleukin-15 receptor subunit alpha isoform X1
       101087763 IL23R; LOW QUALITY PROTEIN: interleukin-23 receptor
       101081364 EPOR; LOW QUALITY PROTEIN: erythropoietin receptor
       101092535 IFNAR1; interferon alpha/beta receptor 1
       101090285 IFNAR2; interferon alpha/beta receptor 2
       101086811 IFNGR1; interferon gamma receptor 1
       101092286 IFNGR2; interferon gamma receptor 2 isoform X1
       101094586 EML4; echinoderm microtubule-associated protein-like 4 isoform X1
       101091689 ALK; ALK tyrosine kinase receptor isoform X2
       101093110 RASGRP1; RAS guanyl-releasing protein 1 isoform X1
       101094450 RASGRP2; RAS guanyl-releasing protein 2 isoform X1
       101085456 RASGRP3; ras guanyl-releasing protein 3 isoform X1
       101094467 RASGRP4; RAS guanyl-releasing protein 4 isoform X1
       101084377 JAK1; tyrosine-protein kinase JAK1
       101088959 JAK2; tyrosine-protein kinase JAK2 isoform X2
       101092339 JAK3; tyrosine-protein kinase JAK3
       101095698 STAT3; signal transducer and activator of transcription 3 isoform X1
       101084561 STAT1; signal transducer and activator of transcription 1-alpha/beta
       101099224 STAT2; signal transducer and activator of transcription 2 isoform X1
       101080650 STAT4; signal transducer and activator of transcription 4 isoform X6
       101089873 STAT6; signal transducer and activator of transcription 6
       493845 VEGFA; vascular endothelial growth factor A precursor
       101092465 VEGFB; vascular endothelial growth factor B isoform X1
       101095904 PGF; placenta growth factor isoform X2
       493703 VEGFD; vascular endothelial growth factor D
       101085368 VEGFC; vascular endothelial growth factor C
       101094921 TGFA; protransforming growth factor alpha isoform X1
       493978 EGF; pro-epidermal growth factor precursor
       100510799 EGFR; epidermal growth factor receptor isoform X1
       751824 ERBB2; receptor tyrosine-protein kinase erbB-2 precursor
       101087287 PDGFA; platelet-derived growth factor subunit A isoform X1
       100135774 PDGFB; platelet-derived growth factor subunit B isoform X4
       101090765 PDGFRA; platelet-derived growth factor receptor alpha
       101084600 PDGFRB; platelet-derived growth factor receptor beta isoform X1
       101101237 IGF1; insulin-like growth factor I isoform X3
       101093644 IGF2; insulin-like growth factor II isoform X3
       100500937 IGF1R; insulin-like growth factor 1 receptor isoform X1
       493937 KITLG; kit ligand precursor
       493766 KIT; mast/stem cell growth factor receptor Kit precursor
       493796 FLT3LG; fms related tyrosine kinase 3 ligand precursor
       101099264 FLT3; receptor-type tyrosine-protein kinase FLT3
       493705 HGF; hepatocyte growth factor precursor
       493669 MET; hepatocyte growth factor receptor precursor
       101082206 FGF1; fibroblast growth factor 1 isoform X1
       100135772 FGF2; LOW QUALITY PROTEIN: fibroblast growth factor 2
       100136904 FGF5; fibroblast growth factor 5 precursor
       101084335 FGF9; fibroblast growth factor 9
       101090606 FGF17; fibroblast growth factor 17 isoform X1
       101091459 FGF6; fibroblast growth factor 6
       101084778 FGF16; fibroblast growth factor 16
       101097982 FGF7; fibroblast growth factor 7 isoform X1
       101098518 FGF18; fibroblast growth factor 18
       111556546 FGF4; fibroblast growth factor 4
       111556666 FGF3; fibroblast growth factor 3
       101084652 FGF8; fibroblast growth factor 8 isoform X1
       101083745 FGF22; fibroblast growth factor 22
       101090489 FGF10; fibroblast growth factor 10
       101083766 FGF20; fibroblast growth factor 20
       101087099 FGF19; fibroblast growth factor 19
       101080595 FGF21; fibroblast growth factor 21
       101100063 FGF23; fibroblast growth factor 23
       101086055 FGFR1; fibroblast growth factor receptor 1 isoform X3
       101095198 FGFR2; fibroblast growth factor receptor 2 isoform X6
       100141386 FGFR3; fibroblast growth factor receptor 3 isoform X1
       101100864 FGFR4; fibroblast growth factor receptor 4 isoform X1
       101099916 GRB2; growth factor receptor-bound protein 2 isoform X1
       101098862 SOS1; son of sevenless homolog 1 isoform X1
       101088847 SOS2; LOW QUALITY PROTEIN: son of sevenless homolog 2
       751103 HRAS; GTPase HRas isoform X1
       751104 KRAS; GTPase KRas
       751105 NRAS; GTPase NRas
       101089839 ARAF; serine/threonine-protein kinase A-Raf
       101092346 BRAF; serine/threonine-protein kinase B-raf isoform X4
       101096047 RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X2
       101081387 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X2
       101100281 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 isoform X1
       101087614 MAPK1; mitogen-activated protein kinase 1
       101087958 MAPK3; mitogen-activated protein kinase 3
       101097261 JUN; transcription factor AP-1
       493935 FOS; proto-oncogene c-Fos
       101090461 ETS1; protein C-ets-1 isoform X1
       101084217 MMP1; interstitial collagenase
       101083957 LOW QUALITY PROTEIN: interstitial collagenase-like
       101098838 MMP2; 72 kDa type IV collagenase
       101084185 MMP9; matrix metalloproteinase-9
       493836 CXCL8; interleukin-8 precursor
       101097903 CDK4; cyclin-dependent kinase 4 isoform X2
       101095179 RPS6KA5; ribosomal protein S6 kinase alpha-5 isoform X1
       101101086 RET; proto-oncogene tyrosine-protein kinase receptor Ret
       101100594 CCDC6; coiled-coil domain-containing protein 6 isoform X1
       101094542 NCOA4; nuclear receptor coactivator 4 isoform X1
       101081603 NTRK1; high affinity nerve growth factor receptor
       101099019 TPM3; tropomyosin alpha-3 chain isoform X6
       101082873 TPR; nucleoprotein TPR isoform X1
       101094042 TFG; protein TFG isoform X1
       101094657 RASSF1; ras association domain-containing protein 1 isoform X3
       101089486 RASSF5; ras association domain-containing protein 5 isoform X1
       101091185 STK4; serine/threonine-protein kinase 4
       101099780 DAPK3; death-associated protein kinase 3
       101089774 DAPK2; death-associated protein kinase 2 isoform X1
       101084322 DAPK1; LOW QUALITY PROTEIN: death-associated protein kinase 1
       101092925 PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1
       101080675 PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
       101095156 ELK1; ETS domain-containing protein Elk-1 isoform X1
       101081534 CALM2; calmodulin-2
       101099307 calmodulin-like protein 3
       102902667 calmodulin-like
       101091063 CALM3; calmodulin-3 isoform X1
       101097703 calmodulin-alpha-like
       101094679 CALM1; calmodulin-1
       111556187 calmodulin-like protein 4
       101086824 CALML6; calmodulin-like protein 6 isoform X1
       101100214 CALML4; calmodulin-like protein 4 isoform X1
       101098221 CAMK2D; calcium/calmodulin-dependent protein kinase type II subunit delta isoform X5
       101098090 CAMK2G; calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X16
       101084342 CAMK2A; calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1
       101098615 CAMK2B; calcium/calmodulin-dependent protein kinase type II subunit beta isoform X1
       101090558 RALGDS; ral guanine nucleotide dissociation stimulator isoform X2
       102899245 ral guanine nucleotide dissociation stimulator-like
       101091003 RALA; ras-related protein Ral-A
       101080471 RALB; ras-related protein Ral-B
       101082017 RALBP1; ralA-binding protein 1
       101094772 CDC42; cell division control protein 42 homolog isoform X1
       101101277 RAC1; ras-related C3 botulinum toxin substrate 1 isoform X1
       101096744 RAC2; ras-related C3 botulinum toxin substrate 2 isoform X1
       101080496 RAC3; ras-related C3 botulinum toxin substrate 3 isoform X1
       101084052 PLD1; phospholipase D1 isoform X3
       101092214 PLD2; phospholipase D2
       101091310 MAPK8; mitogen-activated protein kinase 8 isoform X1
       101101463 MAPK10; mitogen-activated protein kinase 10 isoform X1
       101084765 MAPK9; mitogen-activated protein kinase 9 isoform X1
       101096468 PAX8; paired box protein Pax-8 isoform X1
       101095161 PPARG; peroxisome proliferator-activated receptor gamma isoform X1
       101085757 RXRA; retinoic acid receptor RXR-alpha isoform X2
       101085801 retinoic acid receptor RXR-beta isoform X1
       111556172 retinoic acid receptor RXR-beta isoform X2
       101081273 RXRG; retinoic acid receptor RXR-gamma isoform X2
       101085742 RARB; retinoic acid receptor beta isoform X2
       552888 ESR1; estrogen receptor
       101086317 ESR2; estrogen receptor beta
       101094588 NCOA1; nuclear receptor coactivator 1 isoform X1
       101083330 NCOA3; nuclear receptor coactivator 3 isoform X1
       101100227 SP1; transcription factor Sp1
       101098383 PPARD; peroxisome proliferator-activated receptor delta isoform X1
       101092310 JUP; junction plakoglobin
       101098251 ZBTB16; zinc finger and BTB domain-containing protein 16
       101083048 RARA; retinoic acid receptor alpha isoform X2
       101088573 CCNA2; cyclin-A2
       101085426 CCNA1; cyclin-A1 isoform X1
       101086975 PML; protein PML isoform X1
       101084898 RUNX1; runt-related transcription factor 1 isoform X1
       101080942 RUNX1T1; protein CBFA2T1 isoform X1
       101094951 SPI1; transcription factor PU.1 isoform X4
       105261262 CEBPA; CCAAT/enhancer-binding protein alpha
       101100621 granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform X1
       102901718 granulocyte-macrophage colony-stimulating factor receptor subunit alpha-like
       101089787 CSF3R; granulocyte colony-stimulating factor receptor isoform X1
       493706 CSF1R; macrophage colony-stimulating factor 1 receptor precursor
       101089220 CDKN2A; cyclin-dependent kinase inhibitor 2A
       101098454 E2F1; transcription factor E2F1
       101098067 E2F2; transcription factor E2F2
       101089768 E2F3; transcription factor E2F3 isoform X2
       493947 MAX; protein max
       101084723 ZBTB17; zinc finger and BTB domain-containing protein 17 isoform X1
       101087014 CDKN2B; cyclin-dependent kinase 4 inhibitor B
       100037415 CDK6; cyclin-dependent kinase 6
       101090950 CCND2; G1/S-specific cyclin-D2
       101101311 CCND3; G1/S-specific cyclin-D3 isoform X1
       101092660 CKS1B; cyclin-dependent kinases regulatory subunit 1 isoform X2
       101086011 CKS2; cyclin-dependent kinases regulatory subunit 2
       101099017 SKP1; S-phase kinase-associated protein 1
       101087051 CUL1; cullin-1 isoform X1
       101087758 RBX1; E3 ubiquitin-protein ligase RBX1
       101099275 SKP2; S-phase kinase-associated protein 2 isoform X1
       101093368 CDK2; cyclin-dependent kinase 2 isoform X2
       101086192 CCNE1; G1/S-specific cyclin-E1
       101085347 CCNE2; LOW QUALITY PROTEIN: G1/S-specific cyclin-E2
       101101356 RB1; retinoblastoma-associated protein isoform X1
       101087971 GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta
       101086509 GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma
       493837 BAX; apoptosis regulator BAX
       101093435 BAK1; bcl-2 homologous antagonist/killer
       101092211 DDB2; DNA damage-binding protein 2 isoform X1
       101099613 POLK; DNA polymerase kappa isoform X1
       100144612 TERT; telomerase reverse transcriptase isoform X1
       101091431 MITF; LOW QUALITY PROTEIN: microphthalmia-associated transcription factor
       768263 TGFB1; transforming growth factor beta-1 isoform X2
       101093414 TGFB2; transforming growth factor beta-2 isoform X2
       101098469 TGFB3; transforming growth factor beta-3 isoform X1
       101094057 TGFBR1; TGF-beta receptor type-1 isoform X1
       101091725 TGFBR2; TGF-beta receptor type-2
       101087179 SMAD2; mothers against decapentaplegic homolog 2 isoform X1
       101101387 SMAD3; mothers against decapentaplegic homolog 3
       101093650 SMAD4; mothers against decapentaplegic homolog 4 isoform X1
       101088775 MECOM; MDS1 and EVI1 complex locus protein EVI1 isoform X2
       101095494 CTBP1; C-terminal-binding protein 1 isoform X3
       101099152 CTBP2; C-terminal-binding protein 2 isoform X1
       101088165 HDAC2; histone deacetylase 2 isoform X1
       101099228 HDAC1; histone deacetylase 1 isoform X3
       101089037 MLH1; DNA mismatch repair protein Mlh1 isoform X1
       101082051 MSH2; DNA mismatch repair protein Msh2
       101090919 MSH3; DNA mismatch repair protein Msh3 isoform X1
       101082303 MSH6; DNA mismatch repair protein Msh6 isoform X1
       493878 BRCA2; breast cancer type 2 susceptibility protein homolog
       101089015 RAD51; DNA repair protein RAD51 homolog 1
       493945 FASLG; tumor necrosis factor ligand superfamily member 6
       493881 FAS; tumor necrosis factor receptor superfamily member 6 precursor
       101087871 FADD; FAS-associated death domain protein
       100142684 CASP8; caspase-8 isoform X1
       100502578 BID; BH3-interacting domain death agonist
       102900397 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
       111558033 BBC3; bcl-2-binding component 3
       101084615 BCL2L11; bcl-2-like protein 11 isoform X2
       101098213 cytochrome c
       101094614 cytochrome c
       101088122 cytochrome c-like
       101100947 cytochrome c
       768257 APAF1; apoptotic protease-activating factor 1 isoform X1
       768262 CASP7; caspase-7 isoform X1
       101091260 KEAP1; kelch-like ECH-associated protein 1
       101098812 NFE2L2; nuclear factor erythroid 2-related factor 2 isoform X2
       101092621 HMOX1; heme oxygenase 1
       101097859 NQO1; NAD(P)H dehydrogenase [quinone] 1
       101090936 MGST2; microsomal glutathione S-transferase 2
       101096317 glutathione S-transferase A2 isoform X1
       101097351 GSTO1; glutathione S-transferase omega-1
       101099565 MGST1; microsomal glutathione S-transferase 1 isoform X1
       101090141 GSTO2; glutathione S-transferase omega-2 isoform X3
       101080760 MGST3; microsomal glutathione S-transferase 3
       100169963 GSTM3; glutathione S-transferase Mu 3
       101083114 glutathione S-transferase theta-3-like
       101083370 glutathione S-transferase theta-1 isoform X1
       101092550 glutathione S-transferase theta-1-like
       101085041 GSTA4; glutathione S-transferase A4
       101092798 LOW QUALITY PROTEIN: glutathione S-transferase theta-2B-like
       101100824 glutathione S-transferase Mu 4
       111560471 glutathione S-transferase A2-like
       101084793 glutathione S-transferase A4-like
       101083623 glutathione S-transferase theta-4-like
       101082184 GSTP1; glutathione S-transferase P
       101085222 TXNRD1; thioredoxin reductase 1, cytoplasmic isoform X1
       101090928 TXNRD3; thioredoxin reductase 3 isoform X1
       101101420 TXNRD2; thioredoxin reductase 2, mitochondrial isoform X1
       101092590 VHL; von Hippel-Lindau disease tumor suppressor
       100628309 ELOC; elongin-C
       101098462 elongin-C-like
       100628310 TCEB2; transcription elongation factor B polypeptide 2
       101101182 ELOB; elongin-B isoform X1
       101094429 CUL2; cullin-2 isoform X1
       101090063 EGLN2; egl nine homolog 2 isoform X1
       101082320 EGLN3; egl nine homolog 3
       101089964 EGLN1; egl nine homolog 1 isoform X1
       101096029 FH; fumarate hydratase, mitochondrial
       101083686 HIF1A; hypoxia-inducible factor 1-alpha
       101085621 EPAS1; endothelial PAS domain-containing protein 1 isoform X1
       101093627 ARNT; aryl hydrocarbon receptor nuclear translocator isoform X1
       101087746 ARNT2; aryl hydrocarbon receptor nuclear translocator 2 isoform X3
       101088344 EP300; histone acetyltransferase p300
       101094471 CREBBP; CREB-binding protein isoform X1
       100127104 SLC2A1; solute carrier family 2, facilitated glucose transporter member 1
       101093427 JAG1; protein jagged-1
       101089198 JAG2; protein jagged-2 isoform X1
       101086978 DLL4; delta-like protein 4
       101095456 DLL3; delta-like protein 3
       101083683 DLL1; delta-like protein 1
       101094384 NOTCH1; neurogenic locus notch homolog protein 1
       101091800 NOTCH2; neurogenic locus notch homolog protein 2 isoform X1
       101088469 NOTCH3; neurogenic locus notch homolog protein 3
       101080381 NOTCH4; LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 4
       105260569 LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 4-like
       101091223 HES1; transcription factor HES-1
       101089627 HES5; transcription factor HES-5
       101083681 HEY2; hairy/enhancer-of-split related with YRPW motif protein 2 isoform X1
       101085436 HEY1; hairy/enhancer-of-split related with YRPW motif protein 1
       101089629 HEYL; hairy/enhancer-of-split related with YRPW motif-like protein
       101094727 FLT4; vascular endothelial growth factor receptor 3 isoform X1
       111557492 SHH; sonic hedgehog protein
       101085077 PTCH1; protein patched homolog 1 isoform X4
       101087567 SMO; smoothened homolog
       101090619 KIF7; kinesin-like protein KIF7 isoform X1
       101085156 SUFU; suppressor of fused homolog isoform X4
       101092697 GLI1; zinc finger protein GLI1 isoform X1
       101101401 GLI2; zinc finger protein GLI2
       101089998 GLI3; transcriptional activator GLI3 isoform X3
       100301987 BMP2; bone morphogenetic protein 2
       101100311 BMP4; bone morphogenetic protein 4 isoform X2
       101087058 HHIP; hedgehog-interacting protein
       101089126 PTCH2; protein patched homolog 2 isoform X4
       101081787 AR; androgen receptor isoform X1
       101095825 HSP90AB1; LOW QUALITY PROTEIN: heat shock protein HSP 90-beta
       101094857 HSP90AA1; heat shock protein HSP 90-alpha
       101082249 HSP90B1; endoplasmin
K06765 DCC; deleted in colorectal carcinoma
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K08733 APPL1; DCC-interacting protein 13 alpha
K05689 CDH1; cadherin 1, type 1, E-cadherin
K02105 CTNNB1; catenin beta 1
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K02842 FZD9_10; frizzled 9/10
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03096 FRAT2; frequently rearranged in advanced T-cell lymphomas 2
K01313 F2; coagulation factor II (thrombin) [EC:3.4.21.5]
K09821 AGT; angiotensinogen
K03914 F2R; coagulation factor II (thrombin) receptor
K04236 F2RL3; coagulation factor II (thrombin) receptor-like 3
K04289 LPAR1; lysophosphatidic acid receptor 1
K04291 LPAR2; lysophosphatidic acid receptor 2
K04294 LPAR3; lysophosphatidic acid receptor 3
K04275 LPAR4; lysophosphatidic acid receptor 4
K08390 LPAR5; lysophosphatidic acid receptor 5
K04273 LPAR6; lysophosphatidic acid receptor 6
K04166 AGTR1; angiotensin II receptor type 1
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K07532 ARHGEF12; Rho guanine nucleotide exchange factor 12
K12331 ARHGEF11; Rho guanine nucleotide exchange factor 11
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K19464 PLEKHG5; pleckstrin homology domain-containing family G member 5
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K10031 CXCL12; C-X-C motif chemokine 12
K04189 CXCR4; C-X-C chemokine receptor type 4
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04258 PTGER1; prostaglandin E receptor 1
K04259 PTGER2; prostaglandin E receptor 2
K04260 PTGER3; prostaglandin E receptor 3
K04261 PTGER4; prostaglandin E receptor 4
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K05637 LAMA1_2; laminin, alpha 1/2
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K05717 FN1; fibronectin 1
K06481 ITGA2; integrin alpha 2
K06476 ITGA2B; integrin alpha 2B
K06482 ITGA3; integrin alpha 3
K06485 ITGA6; integrin alpha 6
K06487 ITGAV; integrin alpha V
K05719 ITGB1; integrin beta 1
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K09348 NKX3-1; homeobox protein Nkx-3.1
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K04735 RELA; transcription factor p65
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K02161 BCL2; apoptosis regulator Bcl-2
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K03172 TRAF1; TNF receptor-associated factor 1
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K03174 TRAF3; TNF receptor-associated factor 3
K09848 TRAF4; TNF receptor-associated factor 4
K09849 TRAF5; TNF receptor-associated factor 5
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K07201 FOXO1; forkhead box protein O1
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53; tumor protein p53
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K08878 BCR1; breakpoint cluster region protein [EC:2.7.11.1]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K04702 PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
K08806 PIM2; proto-oncogene serine/threonine-protein kinase Pim-2 [EC:2.7.11.1]
K03898 KNG; kininogen
K16366 EDN1; endothelin-1
K03916 BDKRB2; bradykinin receptor B2
K04197 EDNRA; endothelin receptor type A
K04198 EDNRB; endothelin receptor type B
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K05429 IL2; interleukin 2
K04736 IL3; interleukin 3
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05405 IL6; interleukin 6
K05431 IL7; interleukin 7
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05435 IL13; interleukin 13
K05433 IL15; interleukin 15
K05426 IL23A; interleukin 23 subunit alpha
K05437 EPO; erythropoietin
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K04687 IFNG; interferon gamma
K05068 IL2RA; interleukin 2 receptor alpha
K05069 IL2RB; interleukin 2 receptor beta
K05070 IL2RG; interleukin 2 receptor gamma
K04737 IL3RA; interleukin 3 receptor alpha
K05071 IL4R; interleukin 4 receptor
K04738 CSF2RB; cytokine receptor common subunit beta
K05067 IL5RA. CD125; interleukin 5 receptor alpha
K05055 IL6R; interleukin 6 receptor
K05060 IL6ST; interleukin 6 signal transducer
K05072 IL7R; interleukin 7 receptor
K05063 IL12RB1; interleukin 12 receptor beta-1
K05064 IL12RB2; interleukin 12 receptor beta-2
K05076 IL13RA1; interleukin 13 receptor alpha-1
K05074 IL15RA; interleukin 15 receptor alpha
K05065 IL23R; interleukin 23 receptor
K05079 EPOR; erythropoietin receptor
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K05132 IFNGR1; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K15420 EML4; echinoderm microtubule-associated protein-like 4
K05119 ALK; anaplastic lymphoma kinase [EC:2.7.10.1]
K04350 RASGRP1; RAS guanyl-releasing protein 1
K12361 RASGRP2; RAS guanyl-releasing protein 2
K12362 RASGRP3; RAS guanyl-releasing protein 3
K12363 RASGRP4; RAS guanyl-releasing protein 4
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K11222 STAT4; signal transducer and activator of transcription 4
K11225 STAT6; signal transducer and activator of transcription 6
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05449 VEGFC_D; vascular endothelial growth factor C/D
K08774 TGFA; transforming growth factor, alpha
K04357 EGF; epidermal growth factor
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05459 IGF1; insulin-like growth factor 1
K13769 IGF2; insulin-like growth factor 2
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K05461 KITLG; KIT ligand
K05091 KIT; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05454 FLT3LG; fms-related tyrosine kinase 3 ligand
K05092 FLT3; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K05460 HGF; hepatocyte growth factor
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K02678 ETS1; C-ets-1
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K10030 IL8; interleukin 8
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K04445 RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K09288 CCDC6; coiled-coil domain-containing protein 6
K09289 NCOA4; nuclear receptor coactivator 4
K03176 NTRK1; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K09290 TPM3; tropomyosin 3
K09291 TPR; nucleoprotein TPR
K09292 TFG; protein TFG
K09850 RASSF1; Ras association domain-containing protein 1
K08015 RASSF5; Ras association domain-containing protein 5
K04411 STK4; serine/threonine kinase 4
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04375 ELK1; ETS domain-containing protein Elk-1
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K08773 RALBP1; RalA-binding protein 1
K04393 CDC42; cell division control protein 42
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K09293 PAX8; paired box protein 8
K08530 NR1C3; peroxisome proliferator-activated receptor gamma
K08524 RXRA; retinoid X receptor alpha
K08525 RXRB; retinoid X receptor beta
K08525 RXRB; retinoid X receptor beta
K08526 RXRG; retinoid X receptor gamma
K08528 RARB; retinoic acid receptor beta
K08550 ESR1; estrogen receptor alpha
K08551 ESR2; estrogen receptor beta
K09101 NCOA1; nuclear receptor coactivator 1 [EC:2.3.1.48]
K11256 NCOA3; nuclear receptor coactivator 3 [EC:2.3.1.48]
K04684 SP1; transcription factor Sp1
K04504 NR1C2; peroxisome proliferator-activated receptor delta
K10056 JUP; junction plakoglobin
K10055 ZBTB16; zinc finger and BTB domain-containing protein 16
K08527 RARA; retinoic acid receptor alpha
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K10054 PML; probable transcription factor PML
K08367 RUNX1; runt-related transcription factor 1
K10053 RUNX1T1; CBFA2/RNUX1 translocation partner 1
K09438 SPI1; transcription factor PU.1
K09055 CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
K05066 CSF2RA; granulocyte-macrophage colony-stimulating factor receptor alpha
K05066 CSF2RA; granulocyte-macrophage colony-stimulating factor receptor alpha
K05061 CSF3R; granulocyte colony-stimulating factor receptor
K05090 CSF1R; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04453 MAX; Max protein
K10500 ZBTB17; zinc finger and BTB domain-containing protein 17
K04685 CDKN2B; cyclin-dependent kinase inhibitor 2B
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K02219 CKS1; cyclin-dependent kinase regulatory subunit CKS1
K02219 CKS1; cyclin-dependent kinase regulatory subunit CKS1
K03094 SKP1; S-phase kinase-associated protein 1
K03347 CUL1; cullin 1
K03868 RBX1; RING-box protein 1 [EC:2.3.2.32]
K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K06618 RB1; retinoblastoma-associated protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
K09455 MITF; microphthalmia-associated transcription factor
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04462 MECOM; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
K04496 CTBP; C-terminal binding protein
K04496 CTBP; C-terminal binding protein
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K08734 MLH1; DNA mismatch repair protein MLH1
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K08775 BRCA2; breast cancer 2 susceptibility protein
K04482 RAD51; DNA repair protein RAD51
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K10131 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
K10132 BBC3; Bcl-2-binding component 3
K16341 BCL2L11; Bcl-2-like protein 11
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K10456 KLHL19; kelch-like protein 19
K05638 NFE2L2; nuclear factor erythroid 2-related factor 2
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K00355 NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K03871 VHL; von Hippel-Lindau disease tumor supressor
K03872 ELOC; elongin-C
K03872 ELOC; elongin-C
K03873 ELOB; elongin-B
K03873 ELOB; elongin-B
K03870 CUL2; cullin 2
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K09095 HIF2A; hypoxia-inducible factor 2 alpha
K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
K15589 ARNT2; aryl hydrocarbon receptor nuclear translocator 2
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K07299 SLC2A1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K06052 JAG1; jagged-1
K21635 JAG2; jagged-2
K06051 DLL; delta
K06051 DLL; delta
K06051 DLL; delta
K02599 NOTCH1; Notch 1
K20994 NOTCH2; Notch 2
K20995 NOTCH3; Notch 3
K20996 NOTCH4; Notch 4
K20996 NOTCH4; Notch 4
K06054 HES1; hairy and enhancer of split 1
K06055 HES5; hairy and enhancer of split 5
K09091 HEY; hairy and enhancer of split related with YRPW motif
K09091 HEY; hairy and enhancer of split related with YRPW motif
K09091 HEY; hairy and enhancer of split related with YRPW motif
K05097 FLT4; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K11988 SHH; sonic hedgehog
K06225 PTCH1; patched 1
K06226 SMO; smoothened
K18806 KIF7; kinesin family member 7
K06229 SUFU; suppressor of fused
K16797 GLI1; zinc finger protein GLI1
K16798 GLI2; zinc finger protein GLI2
K06230 GLI3; zinc finger protein GLI3
K21283 BMP2; bone morphogenetic protein 2
K04662 BMP4; bone morphogenetic protein 4
K06231 HHIP; hedgehog interacting protein
K11101 PTCH2; patched 2
K08557 AR; androgen receptor
K04079 HSP90A; molecular chaperone HtpG
K04079 HSP90A; molecular chaperone HtpG
K09487 HSP90B; heat shock protein 90kDa beta
     05202 Transcriptional misregulation in cancer [PATH:fca05202]
     05206 MicroRNAs in cancer [PATH:fca05206]
       101091813 PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1
       493958 CDKN1B; cyclin-dependent kinase inhibitor 1B
       101091215 TIMP3; metalloproteinase inhibitor 3
       751104 KRAS; GTPase KRas
       100037415 CDK6; cyclin-dependent kinase 6
       101098445 CDC25A; M-phase inducer phosphatase 1 isoform X1
       101092757 CDC25B; LOW QUALITY PROTEIN: M-phase inducer phosphatase 2
       101086942 CDC25C; M-phase inducer phosphatase 3 isoform X1
       111561386 HMGA2; high mobility group protein HMGI-C isoform X1
       100037407 CCND1; G1/S-specific cyclin-D1
       101090950 CCND2; G1/S-specific cyclin-D2
       101086192 CCNE1; G1/S-specific cyclin-E1
       101085347 CCNE2; LOW QUALITY PROTEIN: G1/S-specific cyclin-E2
       101084908 CRKL; crk-like protein
       101086100 CRK; adapter molecule crk isoform X1
       101098019 HDAC5; histone deacetylase 5 isoform X3
       101093384 HDAC4; histone deacetylase 4 isoform X5
       101092171 FOXP1; forkhead box protein P1 isoform X2
       493888 PIM1; serine/threonine-protein kinase pim-1
       493669 MET; hepatocyte growth factor receptor precursor
       100510798 DNMT3A; DNA (cytosine-5)-methyltransferase 3A
       101092926 DNMT3B; DNA (cytosine-5)-methyltransferase 3B isoform X4
       493970 MCL1; induced myeloid leukemia cell differentiation protein Mcl-1 homolog
       768265 BCL2L2; bcl-2-like protein 2
       100510799 EGFR; epidermal growth factor receptor isoform X1
       493845 VEGFA; vascular endothelial growth factor A precursor
       101091377 ZEB1; zinc finger E-box-binding homeobox 1 isoform X1
       101093414 TGFB2; transforming growth factor beta-2 isoform X2
       101092519 EZR; ezrin isoform X1
       101093647 PDCD4; programmed cell death protein 4
       101088344 EP300; histone acetyltransferase p300
       101094471 CREBBP; CREB-binding protein isoform X1
       101091450 TPM1; tropomyosin alpha-1 chain isoform X14
       101088453 SPRY2; protein sprouty homolog 2
       493934 BCL2; apoptosis regulator Bcl-2
       101083372 SERPINB5; serpin B5
       101095767 ST14; suppressor of tumorigenicity 14 protein isoform X1
       101099873 cytochrome P450 1B1
       101098152 MTOR; serine/threonine-protein kinase mTOR isoform X1
       101086862 RPTOR; regulatory-associated protein of mTOR isoform X1
       101096141 LOW QUALITY PROTEIN: 1
       751824 ERBB2; receptor tyrosine-protein kinase erbB-2 precursor
       101085388 ERBB3; receptor tyrosine-protein kinase erbB-3 precursor
       101087622 ABL1; tyrosine-protein kinase ABL1 isoform X1
       101095124 TP63; tumor protein 63 isoform X1
       101082586 ZEB2; zinc finger E-box-binding homeobox 2 isoform X1
       101098761 FSCN1; fascin
       101094657 RASSF1; ras association domain-containing protein 1 isoform X3
       101097909 HOXD10; homeobox protein Hox-D10
       101082094 DDIT4; DNA damage-inducible transcript 4 protein
       101091452 BMF; LOW QUALITY PROTEIN: bcl-2-modifying factor
       101098348 PAK4; serine/threonine-protein kinase PAK 4 isoform X1
       101084185 MMP9; matrix metalloproteinase-9
       101089066 SLC7A1; high affinity cationic amino acid transporter 1
       101087709 CCNG1; cyclin-G1
       101092621 HMOX1; heme oxygenase 1
       101082582 STMN1; stathmin
       101095698 STAT3; signal transducer and activator of transcription 3 isoform X1
       100379628 MYC; myc proto-oncogene protein
       493932 CASP3; caspase-3
       751103 HRAS; GTPase HRas isoform X1
       751105 NRAS; GTPase NRas
       101093502 DNMT1; DNA (cytosine-5)-methyltransferase 1 isoform X3
       101096138 APC; adenomatous polyposis coli protein isoform X5
       101097211 APC2; adenomatous polyposis coli protein 2 isoform X1
       101087257 IRS1; insulin receptor substrate 1
       100271864 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X3
       101093286 PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1
       101093586 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
       101097357 MAPK7; mitogen-activated protein kinase 7
       101094274 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
       101091892 PIK3CB; LOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
       101097413 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
       101099911 HNRNPK; heterogeneous nuclear ribonucleoprotein K isoform X1
       101088789 RECK; reversion-inducing cysteine-rich protein with Kazal motifs isoform X1
       101089768 E2F3; transcription factor E2F3 isoform X2
       101095791 IRS2; insulin receptor substrate 2
       101094384 NOTCH1; neurogenic locus notch homolog protein 1
       101091800 NOTCH2; neurogenic locus notch homolog protein 2 isoform X1
       101088469 NOTCH3; neurogenic locus notch homolog protein 3
       101080381 NOTCH4; LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 4
       105260569 LOW QUALITY PROTEIN: neurogenic locus notch homolog protein 4-like
       554342 BMI1; polycomb complex protein BMI-1
       493663 MMP16; matrix metalloproteinase-16 isoform X1
       101089291 ATM; serine-protein kinase ATM isoform X1
       111558242 SOCS1; suppressor of cytokine signaling 1
       101098744 CD44; CD44 antigen isoform X9
       101089449 DICER1; endoribonuclease Dicer isoform X1
       101095250 FZD3; frizzled-3 isoform X1
       101093870 ITGA5; integrin alpha-5
       101090715 RDX; radixin isoform X2
       101084011 RHOA; transforming protein RhoA
       101098338 PLAU; urokinase-type plasminogen activator
       101093435 BAK1; bcl-2 homologous antagonist/killer
       101086875 ZFPM2; zinc finger protein ZFPM2
       101092159 ITGB3; integrin beta-3 isoform X2
       101085770 UBE2I; SUMO-conjugating enzyme UBC9
       111560412 SOX4; transcription factor SOX-4
       101096629 TNR; LOW QUALITY PROTEIN: tenascin-R
       101083629 TNC; tenascin
       101097863 TNN; tenascin-N
       101101563 TNXB; LOW QUALITY PROTEIN: tenascin-X
       493707 ABCB1; multidrug resistance protein 1
       101101279 ABCC1; multidrug resistance-associated protein 1 isoform X1
       101081937 BRCA1; breast cancer type 1 susceptibility protein isoform X1
       493943 CDKN1A; cyclin-dependent kinase inhibitor 1
       101085951 EFNA5; ephrin-A5 isoform X1
       101094570 EFNA1; ephrin-A1 isoform X1
       101094822 EFNA3; ephrin-A3
       111557556 EFNA2; ephrin-A2
       101095077 EFNA4; ephrin-A4 isoform X1
       101092689 THBS1; thrombospondin-1
       101096428 IGF2BP1; insulin-like growth factor 2 mRNA-binding protein 1 isoform X1
       101096006 TRIM71; E3 ubiquitin-protein ligase TRIM71
       100142683 NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1
       100142682 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X2
       100126581 PTGS2; prostaglandin G/H synthase 2 precursor
       101087614 MAPK1; mitogen-activated protein kinase 1
       101087958 MAPK3; mitogen-activated protein kinase 3
       101086433 PRKCA; protein kinase C alpha type isoform X1
       101088970 PRKCB; protein kinase C beta type isoform X3
       101082196 PRKCG; protein kinase C gamma type
       101099916 GRB2; growth factor receptor-bound protein 2 isoform X1
       100141386 FGFR3; fibroblast growth factor receptor 3 isoform X1
       101095179 RPS6KA5; ribosomal protein S6 kinase alpha-5 isoform X1
       493847 TP53; cellular tumor antigen p53
       493939 MDM2; E3 ubiquitin-protein ligase Mdm2
       101082460 MDM4; protein Mdm4 isoform X3
       101090765 PDGFRA; platelet-derived growth factor receptor alpha
       101092925 PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1
       101080675 PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
       101096047 RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X2
       101081387 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X2
       101100281 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 isoform X1
       101098862 SOS1; son of sevenless homolog 1 isoform X1
       101088847 SOS2; LOW QUALITY PROTEIN: son of sevenless homolog 2
       101092911 SHC1; LOW QUALITY PROTEIN: SHC-transforming protein 1
       101087287 PDGFA; platelet-derived growth factor subunit A isoform X1
       101099050 SHC4; SHC-transforming protein 4
       100135774 PDGFB; platelet-derived growth factor subunit B isoform X4
       101084600 PDGFRB; platelet-derived growth factor receptor beta isoform X1
       101089220 CDKN2A; cyclin-dependent kinase inhibitor 2A
       101098454 E2F1; transcription factor E2F1
       101098067 E2F2; transcription factor E2F2
       101084615 BCL2L11; bcl-2-like protein 11 isoform X2
       111560514 MARCKS; myristoylated alanine-rich C-kinase substrate
       101096338 BMPR2; bone morphogenetic protein receptor type-2
       101088165 HDAC2; histone deacetylase 2 isoform X1
       101099228 HDAC1; histone deacetylase 1 isoform X3
       101087309 EZH2; LOW QUALITY PROTEIN: histone-lysine N-methyltransferase EZH2
       101100228 GLS2; glutaminase liver isoform, mitochondrial isoform X1
       101080395 GLS; glutaminase kidney isoform, mitochondrial isoform X4
       101087610 SIRT1; NAD-dependent protein deacetylase sirtuin-1
       101088533 WNT3; proto-oncogene Wnt-3
       101080607 WNT3A; protein Wnt-3a
       101083033 CDCA5; sororin isoform X3
       101098230 KIF23; kinesin-like protein KIF23 isoform X1
       101092552 ROCK1; rho-associated protein kinase 1 isoform X1
       101100958 PRKCE; protein kinase C epsilon type isoform X1
       101086368 SLC45A3; solute carrier family 45 member 3
       101091951 VIM; vimentin
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K16866 TIMP3; metalloproteinase inhibitor 3
K07827 KRAS; GTPase KRas
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
K05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
K09283 HMGA2; high mobility group AT-hook protein 2
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K11406 HDAC4_5; histone deacetylase 4/5 [EC:3.5.1.98]
K11406 HDAC4_5; histone deacetylase 4/5 [EC:3.5.1.98]
K23582 FOXP1; forkhead box protein P1
K04702 PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K17398 DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]
K17399 DNMT3B; DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37]
K02539 MCL1; myeloid leukemia cell differntiation protein MCL-1
K02163 BCLW; apoptosis regulator BCL-W
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05448 VEGFA; vascular endothelial growth factor A
K09299 ZEB1; zinc finger homeobox protein 1
K13376 TGFB2; transforming growth factor beta-2
K08007 VIL2; villin 2 (ezrin)
K16865 PDCD4; programmed cell death protein 4
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K10373 TPM1; tropomyosin 1
K17383 SPRY2; protein sprouty homolog 2
K02161 BCL2; apoptosis regulator Bcl-2
K10139 SERPINB5; serpin B5
K08670 ST14; suppressor of tumorigenicity protein 14 [EC:3.4.21.109]
K07410 CYP1B1; cytochrome P450 family 1 subfamily B1 [EC:1.14.14.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07204 RAPTOR; regulatory associated protein of mTOR
K07436 CYP24A1; vitamin D3 24-hydroxylase [EC:1.14.15.16]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05084 ERBB3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K10149 TP63; tumor protein p63
K23560 ZEB2; zinc finger homeobox protein 2
K23551 FSCN1; fascin 1
K09850 RASSF1; Ras association domain-containing protein 1
K09295 HOXD10; homrobox protein Hox-D10
K08270 DDIT4; DNA-damage-inducible transcript 4
K17460 BMF; Bcl-2-modifying factor
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K13863 SLC7A1; solute carrier family 7 (cationic amino acid transporter), member 1
K10145 CCNG1; cyclin G1
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K04381 STMN1; stathmin
K04692 STAT3; signal transducer and activator of transcription 3
K04377 MYC; Myc proto-oncogene protein
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K02833 HRAS; GTPase HRas
K07828 NRAS; GTPase NRas
K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K16172 IRS1; insulin receptor substrate 1
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04464 MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K12886 HNRNPK; heterogeneous nuclear ribonucleoprotein K
K17461 RECK; reversion-inducing-cysteine-rich protein with kazal motifs
K06620 E2F3; transcription factor E2F3
K07187 IRS2; insulin receptor substrate 2
K02599 NOTCH1; Notch 1
K20994 NOTCH2; Notch 2
K20995 NOTCH3; Notch 3
K20996 NOTCH4; Notch 4
K20996 NOTCH4; Notch 4
K11459 PCGF4; polycomb group RING finger protein 4
K07996 MMP16; matrix metalloproteinase-16 (membrane-inserted) [EC:3.4.24.-]
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K04694 SOCS1; suppressor of cytokine signaling 1
K06256 CD44; CD44 antigen
K11592 DICER1; endoribonuclease Dicer [EC:3.1.26.-]
K02329 FZD3; frizzled 3
K06484 ITGA5; integrin alpha 5
K05762 RDX; radixin
K04513 RHOA; Ras homolog gene family, member A
K01348 PLAU; urokinase plasminogen activator [EC:3.4.21.73]
K14021 BAK; Bcl-2 homologous antagonist/killer
K17442 ZFPM2; zinc finger protein ZFPM2
K06493 ITGB3; integrin beta 3
K10577 UBE2I; ubiquitin-conjugating enzyme E2 I
K23581 SOX4; transcription factor SOX4 (SOX group C)
K06252 TN; tenascin
K06252 TN; tenascin
K06252 TN; tenascin
K06252 TN; tenascin
K05658 ABCB1; ATP-binding cassette, subfamily B (MDR/TAP), member 1 [EC:7.6.2.2]
K05665 ABCC1; ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3]
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K05462 EFNA; ephrin-A
K16857 THBS1; thrombospondin 1
K17391 IGF2BP1; insulin-like growth factor 2 mRNA-binding protein 1
K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04364 GRB2; growth factor receptor-bound protein 2
K05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K04445 RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K04451 TP53; tumor protein p53
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K10127 MDM4; protein Mdm4
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K06279 SHC1; SHC-transforming protein 1
K04359 PDGFA; platelet-derived growth factor subunit A
K17449 SHC4; SHC-transforming protein 4
K17386 PDGFB; platelet-derived growth factor subunit B
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K16341 BCL2L11; Bcl-2-like protein 11
K12561 MARCKS; myristoylated alanine-rich C-kinase substrate
K04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K11430 EZH2; [histone H3]-lysine27 N-trimethyltransferase EZH2 [EC:2.1.1.356]
K01425 glsA; glutaminase [EC:3.5.1.2]
K01425 glsA; glutaminase [EC:3.5.1.2]
K11411 SIRT1; NAD+-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K17390 CDCA5; sororin
K17387 KIF23; kinesin family member 23
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
K15379 SLC45A3; solute carrier family 45, member 3
K07606 VIM; vimentin
     05205 Proteoglycans in cancer [PATH:fca05205]
     05204 Chemical carcinogenesis [PATH:fca05204]
     05203 Viral carcinogenesis [PATH:fca05203]
     05230 Central carbon metabolism in cancer [PATH:fca05230]
     05231 Choline metabolism in cancer [PATH:fca05231]
     05235 PD-L1 expression and PD-1 checkpoint pathway in cancer [PATH:fca05235]
 
   09162 Cancer: specific types
     05210 Colorectal cancer [PATH:fca05210]
     05212 Pancreatic cancer [PATH:fca05212]
     05225 Hepatocellular carcinoma [PATH:fca05225]
     05226 Gastric cancer [PATH:fca05226]
     05214 Glioma [PATH:fca05214]
     05216 Thyroid cancer [PATH:fca05216]
     05221 Acute myeloid leukemia [PATH:fca05221]
     05220 Chronic myeloid leukemia [PATH:fca05220]
     05217 Basal cell carcinoma [PATH:fca05217]
     05218 Melanoma [PATH:fca05218]
     05211 Renal cell carcinoma [PATH:fca05211]
     05219 Bladder cancer [PATH:fca05219]
       100141386 FGFR3; fibroblast growth factor receptor 3 isoform X1
       751103 HRAS; GTPase HRas isoform X1
       751104 KRAS; GTPase KRas
       751105 NRAS; GTPase NRas
       101089839 ARAF; serine/threonine-protein kinase A-Raf
       101092346 BRAF; serine/threonine-protein kinase B-raf isoform X4
       101096047 RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X2
       101081387 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X2
       101100281 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 isoform X1
       101087614 MAPK1; mitogen-activated protein kinase 1
       101087958 MAPK3; mitogen-activated protein kinase 3
       101095179 RPS6KA5; ribosomal protein S6 kinase alpha-5 isoform X1
       100379628 MYC; myc proto-oncogene protein
       101094657 RASSF1; ras association domain-containing protein 1 isoform X3
       101099780 DAPK3; death-associated protein kinase 3
       101089774 DAPK2; death-associated protein kinase 2 isoform X1
       101084322 DAPK1; LOW QUALITY PROTEIN: death-associated protein kinase 1
       101089220 CDKN2A; cyclin-dependent kinase inhibitor 2A
       493939 MDM2; E3 ubiquitin-protein ligase Mdm2
       493847 TP53; cellular tumor antigen p53
       493943 CDKN1A; cyclin-dependent kinase inhibitor 1
       100037407 CCND1; G1/S-specific cyclin-D1
       101097903 CDK4; cyclin-dependent kinase 4 isoform X2
       101101356 RB1; retinoblastoma-associated protein isoform X1
       101098454 E2F1; transcription factor E2F1
       101098067 E2F2; transcription factor E2F2
       101089768 E2F3; transcription factor E2F3 isoform X2
       101092689 THBS1; thrombospondin-1
       101093578 HBEGF; proheparin-binding EGF-like growth factor
       101098838 MMP2; 72 kDa type IV collagenase
       101084185 MMP9; matrix metalloproteinase-9
       101088858 UPK3A; uroplakin-3a isoform X1
       101100378 SRC; proto-oncogene tyrosine-protein kinase Src isoform X3
       493978 EGF; pro-epidermal growth factor precursor
       751824 ERBB2; receptor tyrosine-protein kinase erbB-2 precursor
       100510799 EGFR; epidermal growth factor receptor isoform X1
       493845 VEGFA; vascular endothelial growth factor A precursor
       101084217 MMP1; interstitial collagenase
       101083957 LOW QUALITY PROTEIN: interstitial collagenase-like
       493836 CXCL8; interleukin-8 precursor
       101095391 CDH1; cadherin-1
K05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04445 RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K04377 MYC; Myc proto-oncogene protein
K09850 RASSF1; Ras association domain-containing protein 1
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04503 CCND1; G1/S-specific cyclin-D1
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K16857 THBS1; thrombospondin 1
K08523 HBEGF; heparin-binding EGF-like growth factor
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K19520 UPK3A; uroplakin-3a
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K04357 EGF; epidermal growth factor
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05448 VEGFA; vascular endothelial growth factor A
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K10030 IL8; interleukin 8
K05689 CDH1; cadherin 1, type 1, E-cadherin
     05215 Prostate cancer [PATH:fca05215]
     05213 Endometrial cancer [PATH:fca05213]
     05224 Breast cancer [PATH:fca05224]
     05222 Small cell lung cancer [PATH:fca05222]
     05223 Non-small cell lung cancer [PATH:fca05223]
       101082731 FHIT; bis(5'-adenosyl)-triphosphatase isoform X4
       101085742 RARB; retinoic acid receptor beta isoform X2
       101085757 RXRA; retinoic acid receptor RXR-alpha isoform X2
       101085801 retinoic acid receptor RXR-beta isoform X1
       111556172 retinoic acid receptor RXR-beta isoform X2
       101081273 RXRG; retinoic acid receptor RXR-gamma isoform X2
       101089220 CDKN2A; cyclin-dependent kinase inhibitor 2A
       101097903 CDK4; cyclin-dependent kinase 4 isoform X2
       100037415 CDK6; cyclin-dependent kinase 6
       100037407 CCND1; G1/S-specific cyclin-D1
       101101356 RB1; retinoblastoma-associated protein isoform X1
       101098454 E2F1; transcription factor E2F1
       101098067 E2F2; transcription factor E2F2
       101089768 E2F3; transcription factor E2F3 isoform X2
       751104 KRAS; GTPase KRas
       101094657 RASSF1; ras association domain-containing protein 1 isoform X3
       101089486 RASSF5; ras association domain-containing protein 5 isoform X1
       101091185 STK4; serine/threonine-protein kinase 4
       101094274 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
       101091892 PIK3CB; LOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
       101097413 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
       100271864 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X3
       101093286 PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1
       101093586 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
       101101686 PDPK1; 3-phosphoinositide-dependent protein kinase 1 isoform X2
       101087931 AKT1; RAC-alpha serine/threonine-protein kinase
       101092818 AKT3; RAC-gamma serine/threonine-protein kinase isoform X2
       100499544 AKT2; RAC-beta serine/threonine-protein kinase isoform X1
       768269 BAD; bcl2-associated agonist of cell death
       768260 CASP9; caspase-9 isoform X1
       101081548 FOXO3; forkhead box protein O3
       493978 EGF; pro-epidermal growth factor precursor
       101094921 TGFA; protransforming growth factor alpha isoform X1
       100510799 EGFR; epidermal growth factor receptor isoform X1
       751824 ERBB2; receptor tyrosine-protein kinase erbB-2 precursor
       493705 HGF; hepatocyte growth factor precursor
       493669 MET; hepatocyte growth factor receptor precursor
       101099916 GRB2; growth factor receptor-bound protein 2 isoform X1
       101098862 SOS1; son of sevenless homolog 1 isoform X1
       101088847 SOS2; LOW QUALITY PROTEIN: son of sevenless homolog 2
       751103 HRAS; GTPase HRas isoform X1
       751105 NRAS; GTPase NRas
       101089839 ARAF; serine/threonine-protein kinase A-Raf
       101092346 BRAF; serine/threonine-protein kinase B-raf isoform X4
       101096047 RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X2
       101081387 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X2
       101100281 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 isoform X1
       101087614 MAPK1; mitogen-activated protein kinase 1
       101087958 MAPK3; mitogen-activated protein kinase 3
       101092925 PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1
       101080675 PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
       101086433 PRKCA; protein kinase C alpha type isoform X1
       101088970 PRKCB; protein kinase C beta type isoform X3
       101082196 PRKCG; protein kinase C gamma type
       493847 TP53; cellular tumor antigen p53
       493943 CDKN1A; cyclin-dependent kinase inhibitor 1
       101087971 GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta
       101086509 GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma
       493837 BAX; apoptosis regulator BAX
       101093435 BAK1; bcl-2 homologous antagonist/killer
       101092211 DDB2; DNA damage-binding protein 2 isoform X1
       101099613 POLK; DNA polymerase kappa isoform X1
       101094768 KIF5A; kinesin heavy chain isoform X2
       101098883 KIF5C; kinesin heavy chain
       101092693 KIF5B; kinesin-1 heavy chain
       101101086 RET; proto-oncogene tyrosine-protein kinase receptor Ret
       101094586 EML4; echinoderm microtubule-associated protein-like 4 isoform X1
       101091689 ALK; ALK tyrosine kinase receptor isoform X2
       101092339 JAK3; tyrosine-protein kinase JAK3
       101095698 STAT3; signal transducer and activator of transcription 3 isoform X1
       101090913 signal transducer and activator of transcription 5A isoform X1
       101090663 STAT5B; LOW QUALITY PROTEIN: signal transducer and activator of transcription 5B
K01522 FHIT; bis(5'-adenosyl)-triphosphatase [EC:3.6.1.29]
K08528 RARB; retinoic acid receptor beta
K08524 RXRA; retinoid X receptor alpha
K08525 RXRB; retinoid X receptor beta
K08525 RXRB; retinoid X receptor beta
K08526 RXRG; retinoid X receptor gamma
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K04503 CCND1; G1/S-specific cyclin-D1
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K07827 KRAS; GTPase KRas
K09850 RASSF1; Ras association domain-containing protein 1
K08015 RASSF5; Ras association domain-containing protein 5
K04411 STK4; serine/threonine kinase 4
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K09408 FOXO3; forkhead box protein O3
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05460 HGF; hepatocyte growth factor
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K10396 KIF5; kinesin family member 5
K10396 KIF5; kinesin family member 5
K10396 KIF5; kinesin family member 5
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K15420 EML4; echinoderm microtubule-associated protein-like 4
K05119 ALK; anaplastic lymphoma kinase [EC:2.7.10.1]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
 
   09163 Immune disease
 
   09164 Neurodegenerative disease
 
   09165 Substance dependence
 
   09166 Cardiovascular disease
 
   09167 Endocrine and metabolic disease
 
   09171 Infectious disease: bacterial
 
   09172 Infectious disease: viral
 
   09174 Infectious disease: parasitic
 
   09175 Drug resistance: antimicrobial
 
   09176 Drug resistance: antineoplastic
 
 09180 Brite Hierarchies
 
 09190 Not Included in Pathway or Brite

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: November 29, 2020