KEGG Orthology (KO) - Falco cherrug (Saker falcon)

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     KO
 09100 Metabolism
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
   09131 Membrane transport
 
   09132 Signal transduction
     02020 Two-component system
     04010 MAPK signaling pathway [PATH:fch04010]
     04013 MAPK signaling pathway - fly
     04016 MAPK signaling pathway - plant
     04011 MAPK signaling pathway - yeast
     04012 ErbB signaling pathway [PATH:fch04012]
       102049265 EGF; pro-epidermal growth factor
       102057058 TGFA; protransforming growth factor alpha
       102057791 AREG; amphiregulin
       102058683 EGFR; epidermal growth factor receptor isoform X1
       102057575 ERBB2; receptor tyrosine-protein kinase erbB-2
       102057302 PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
       102046961 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1-like isoform X1
       102058636 PLCG2; LOW QUALITY PROTEIN: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
       102052104 CAMK2A; calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1
       102057655 CAMK2G; calcium/calmodulin-dependent protein kinase type II subunit gamma
       102051471 CAMK2D; calcium/calmodulin-dependent protein kinase type II subunit delta isoform X1
       102053069 PRKCA; protein kinase C alpha type
       102047370 PRKCB; protein kinase C beta type
       102049511 protein kinase C gamma type
       102058724 CBL; E3 ubiquitin-protein ligase CBL
       102053933 CBLB; E3 ubiquitin-protein ligase CBL-B isoform X1
       102053699 signal transducer and activator of transcription 5B
       102052372 SRC; proto-oncogene tyrosine-protein kinase Src isoform X2
       102059158 PTK2; focal adhesion kinase 1 isoform X9
       102048492 CRK; adapter molecule crk
       102051164 CRKL; crk-like protein
       102052443 ABL1; tyrosine-protein kinase ABL1 isoform X1
       102045785 ABL2; tyrosine-protein kinase ABL2
       102056394 NCK2; cytoplasmic protein NCK2
       102053816 PAK1; serine/threonine-protein kinase PAK 1
       102046818 PAK2; serine/threonine-protein kinase PAK 2
       102049349 PAK3; serine/threonine-protein kinase PAK 3 isoform X1
       102047228 serine/threonine-protein kinase PAK 4-like
       102054246 PAK5; serine/threonine-protein kinase PAK 5
       102047737 PAK6; serine/threonine-protein kinase PAK 6
       102047307 MAP2K4; dual specificity mitogen-activated protein kinase kinase 4 isoform X3
       102048069 dual specificity mitogen-activated protein kinase kinase 7
       102054176 MAPK10; mitogen-activated protein kinase 10 isoform X1
       102055660 MAPK9; mitogen-activated protein kinase 9 isoform X2
       102047380 MAPK8; mitogen-activated protein kinase 8 isoform X1
       102050406 JUN; transcription factor AP-1
       102052299 BTC; probetacellulin
       102052533 HBEGF; proheparin-binding EGF-like growth factor
       102057621 EREG; proepiregulin
       102056537 uncharacterized protein LOC102056537
       102056349 NRG1; pro-neuregulin-1, membrane-bound isoform isoform X1
       102053051 NRG2; pro-neuregulin-2, membrane-bound isoform
       102046664 ERBB4; receptor tyrosine-protein kinase erbB-4
       102048929 SHC1; SHC-transforming protein 1
       102049085 SHC2; SHC-transforming protein 2 isoform X1
       102053453 SHC3; SHC-transforming protein 3 isoform X1
       102053624 SHC4; SHC-transforming protein 4 isoform X1
       102057209 GRB2; growth factor receptor-bound protein 2
       102052422 SOS1; son of sevenless homolog 1 isoform X1
       102056424 SOS2; son of sevenless homolog 2
       102055506 HRAS; GTPase HRas
       102052019 KRAS; GTPase KRas isoform X1
       102054942 NRAS; GTPase NRas
       102056938 BRAF; serine/threonine-protein kinase B-raf isoform X1
       102051503 RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1
       102053397 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X1
       102049695 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2
       102048221 MAPK1; LOW QUALITY PROTEIN: mitogen-activated protein kinase 1
       102056832 MYC; myc proto-oncogene protein
       102060203 GAB1; GRB2-associated-binding protein 1
       102054634 NRG4; pro-neuregulin-4, membrane-bound isoform isoform X1
       102049812 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
       102057414 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
       102049197 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
       102056135 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1
       102059517 phosphatidylinositol 3-kinase regulatory subunit gamma isoform X2
       102057083 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
       102060018 AKT2; RAC-beta serine/threonine-protein kinase
       102055811 AKT1; RAC-alpha serine/threonine-protein kinase
       102050094 AKT3; RAC-gamma serine/threonine-protein kinase isoform X1
       102051979 MTOR; serine/threonine-protein kinase mTOR
       102057985 RPS6KB1; ribosomal protein S6 kinase beta-1
       102047520 EIF4EBP1; eukaryotic translation initiation factor 4E-binding protein 1
       102059271 GSK3B; glycogen synthase kinase-3 beta isoform X1
       102051672 CDKN1B; cyclin-dependent kinase inhibitor 1B
       114014226 CDKN1A; cyclin-dependent kinase inhibitor 1
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K09782 AREG; amphiregulin
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K22517 CBLB; E3 ubiquitin-protein ligase CBL-B [EC:2.3.2.27]
K11224 STAT5B; signal transducer and activator of transcription 5B
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K08887 ABL2; abelson tyrosine-protein kinase 2 [EC:2.7.10.2]
K19862 NCK2; NCK adaptor protein 2
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3; p21-activated kinase 3 [EC:2.7.11.1]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K05736 PAK5; p21-activated kinase 5 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K04430 MAP2K4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K09783 BTC; betacellulin
K08523 HBEGF; heparin-binding EGF-like growth factor
K09784 EREG; epiregulin
K05084 ERBB3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
K05455 NRG1; neuregulin 1
K05456 NRG2; neuregulin 2
K05085 ERBB4; receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04377 MYC; Myc proto-oncogene protein
K09593 GAB1; GRB2-associated-binding protein 1
K05458 NRG4; neuregulin 4
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
     04014 Ras signaling pathway
     04015 Rap1 signaling pathway
     04310 Wnt signaling pathway [PATH:fch04310]
     04330 Notch signaling pathway [PATH:fch04330]
     04340 Hedgehog signaling pathway [PATH:fch04340]
     04341 Hedgehog signaling pathway - fly
     04350 TGF-beta signaling pathway [PATH:fch04350]
     04390 Hippo signaling pathway
     04391 Hippo signaling pathway - fly
     04392 Hippo signaling pathway - multiple species
     04370 VEGF signaling pathway [PATH:fch04370]
     04371 Apelin signaling pathway [PATH:fch04371]
     04630 JAK-STAT signaling pathway
     04064 NF-kappa B signaling pathway
     04668 TNF signaling pathway
     04066 HIF-1 signaling pathway
     04068 FoxO signaling pathway [PATH:fch04068]
       102047778 TGFB2; transforming growth factor beta-2 proprotein
       102055453 TGFB3; transforming growth factor beta-3 proprotein
       102055038 TGFBR1; TGF-beta receptor type-1
       102048632 TGF-beta receptor type-2-like
       102053489 TGFBR2; TGF-beta receptor type-2
       102057734 SMAD4; mothers against decapentaplegic homolog 4 isoform X1
       102048236 mothers against decapentaplegic homolog 4-like
       102053568 SMAD3; mothers against decapentaplegic homolog 3 isoform X1
       102055692 STK11; serine/threonine-protein kinase STK11
       102049360 PRKAA2; 5'-AMP-activated protein kinase catalytic subunit alpha-2 isoform X1
       102050598 PRKAA1; 5'-AMP-activated protein kinase catalytic subunit alpha-1
       102054722 PRKAB2; 5'-AMP-activated protein kinase subunit beta-2 isoform X1
       102057661 PRKAB1; 5'-AMP-activated protein kinase subunit beta-1
       102049283 PRKAG1; LOW QUALITY PROTEIN: 5'-AMP-activated protein kinase subunit gamma-1
       102054583 PRKAG3; 5'-AMP-activated protein kinase subunit gamma-3
       102047539 5'-AMP-activated protein kinase subunit gamma-2
       102053931 NLK; serine/threonine-protein kinase NLK isoform X1
       102053148 SKP2; S-phase kinase-associated protein 2
       102048171 MDM2; E3 ubiquitin-protein ligase Mdm2 isoform X1
       102053523 SETD7; histone-lysine N-methyltransferase SETD7
       102056653 CREBBP; LOW QUALITY PROTEIN: CREB-binding protein
       102045802 EP300; histone acetyltransferase p300 isoform X2
       102058467 SIRT1; NAD-dependent protein deacetylase sirtuin-1
       102048670 USP7; ubiquitin carboxyl-terminal hydrolase 7 isoform X1
       102054176 MAPK10; mitogen-activated protein kinase 10 isoform X1
       102055660 MAPK9; mitogen-activated protein kinase 9 isoform X2
       102047380 MAPK8; mitogen-activated protein kinase 8 isoform X1
       102055434 STK4; serine/threonine-protein kinase 4
       102060062 IGF1; insulin-like growth factor I
       102046128 IGF1R; insulin-like growth factor 1 receptor isoform X1
       102054961 INS; LOW QUALITY PROTEIN: insulin
       102056291 INSR; insulin receptor
       102052001 IRS1; insulin receptor substrate 1
       102052095 IRS4; insulin receptor substrate 4
       102046894 IRS2; insulin receptor substrate 2
       102049812 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
       102057414 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
       102049197 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
       102056135 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1
       102059517 phosphatidylinositol 3-kinase regulatory subunit gamma isoform X2
       102057083 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
       102054066 PDPK1; 3-phosphoinositide-dependent protein kinase 1 isoform X4
       102053491 CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X2
       102058892 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta
       102050194 PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1
       102060018 AKT2; RAC-beta serine/threonine-protein kinase
       102055811 AKT1; RAC-alpha serine/threonine-protein kinase
       102050094 AKT3; RAC-gamma serine/threonine-protein kinase isoform X1
       102052186 serine/threonine-protein kinase Sgk1 isoform X1
       102049201 SGK2; serine/threonine-protein kinase Sgk2 isoform X1
       102059079 serine/threonine-protein kinase Sgk3 isoform X1
       102057600 FOXO1; forkhead box protein O1
       102052285 FOXO3; forkhead box protein O3 isoform X1
       102053049 FOXO4; forkhead box protein O4
       102054496 HOMER2; homer protein homolog 2
       102049013 HOMER1; homer protein homolog 1
       102045712 HOMER3; homer protein homolog 3 isoform X3
       102047434 casein kinase I
       102058451 LOW QUALITY PROTEIN: casein kinase I-like
       102047657 IL6; interleukin-6
       102051109 IL10; interleukin-10
       102053408 STAT3; signal transducer and activator of transcription 3 isoform X1
       102049265 EGF; pro-epidermal growth factor
       102058683 EGFR; epidermal growth factor receptor isoform X1
       102057209 GRB2; growth factor receptor-bound protein 2
       102052422 SOS1; son of sevenless homolog 1 isoform X1
       102056424 SOS2; son of sevenless homolog 2
       102055506 HRAS; GTPase HRas
       102052019 KRAS; GTPase KRas isoform X1
       102054942 NRAS; GTPase NRas
       102056938 BRAF; serine/threonine-protein kinase B-raf isoform X1
       102051503 RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1
       102053397 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X1
       102049695 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2
       102048221 MAPK1; LOW QUALITY PROTEIN: mitogen-activated protein kinase 1
       102059377 MAPK14; mitogen-activated protein kinase 14 isoform X1
       102054359 MAPK13; mitogen-activated protein kinase 13 isoform X1
       102051874 MAPK12; mitogen-activated protein kinase 12 isoform X1
       102052038 MAPK11; mitogen-activated protein kinase 11
       102048468 PRMT1; protein arginine N-methyltransferase 1
       102049722 FOXG1; forkhead box protein G1
       102046409 CCNB1; LOW QUALITY PROTEIN: G2/mitotic-specific cyclin-B1
       102054317 CCNB2; G2/mitotic-specific cyclin-B2
       102051864 CCNB3; G2/mitotic-specific cyclin-B3 isoform X1
       102053036 CCND1; G1/S-specific cyclin-D1
       102053549 CCND2; G1/S-specific cyclin-D2
       102054033 CCNG2; cyclin-G2
       114014226 CDKN1A; cyclin-dependent kinase inhibitor 1
       102051672 CDKN1B; cyclin-dependent kinase inhibitor 1B
       102056460 RBL2; retinoblastoma-like protein 2 isoform X2
       102046673 PLK1; serine/threonine-protein kinase PLK1
       102048461 PLK2; serine/threonine-protein kinase PLK2
       102049980 PLK3; serine/threonine-protein kinase PLK3 isoform X2
       102059128 PLK4; serine/threonine-protein kinase PLK4
       102057224 GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma
       102057932 GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta
       102046752 FASLG; tumor necrosis factor ligand superfamily member 6
       102047699 TNFSF10; tumor necrosis factor ligand superfamily member 10 isoform X1
       102049546 BCL6; B-cell lymphoma 6 protein
       106631163 BNIP3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
       106631468 ATG12; ubiquitin-like protein ATG12
       102047079 GABARAPL1; gamma-aminobutyric acid receptor-associated protein-like 1
       102058869 GABARAPL2; gamma-aminobutyric acid receptor-associated protein-like 2
       102057737 CAT; catalase
       102047193 SOD2; superoxide dismutase [Mn], mitochondrial
       102058832 ATM; serine-protein kinase ATM
       102052060 PCK1; phosphoenolpyruvate carboxykinase, cytosolic [GTP]
       102052041 G6PC; glucose-6-phosphatase
       102056383 G6PC3; glucose-6-phosphatase 3 isoform X4
       102052276 G6PC2; glucose-6-phosphatase 2 isoform X1
       102052979 IL7R; interleukin-7 receptor subunit alpha isoform X1
       102060015 KLF2; Krueppel-like factor 2
       102050605 S1PR1; sphingosine 1-phosphate receptor 1
       102053893 S1PR4; sphingosine 1-phosphate receptor 4
       102058214 RAG1; LOW QUALITY PROTEIN: V(D)J recombination-activating protein 1
       102058383 RAG2; V(D)J recombination-activating protein 2
       102055601 FBXO32; F-box only protein 32
       102056316 FBXO25; F-box only protein 25 isoform X4
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04501 SMAD4; mothers against decapentaplegic homolog 4
K23605 SMAD3; mothers against decapentaplegic homolog 3
K07298 STK11; serine/threonine-protein kinase 11 [EC:2.7.11.1]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K04468 NLK; nemo like kinase [EC:2.7.11.24]
K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K11431 SETD7; [histone H3]-lysine4 N-methyltransferase [EC:2.1.1.364]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K11411 SIRT1; NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04411 STK4; serine/threonine kinase 4
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04526 INS; insulin
K04527 INSR; insulin receptor [EC:2.7.10.1]
K16172 IRS1; insulin receptor substrate 1
K07187 IRS2; insulin receptor substrate 2
K07187 IRS2; insulin receptor substrate 2
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K13302 SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
K13303 SGK2; serum/glucocorticoid-regulated kinase 2 [EC:2.7.11.1]
K13304 SGK3; serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1]
K07201 FOXO1; forkhead box protein O1
K09408 FOXO3; forkhead box protein O3
K12358 FOXO4; forkhead box protein O4
K15010 HOMER; homer
K15010 HOMER; homer
K15010 HOMER; homer
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K05405 IL6; interleukin 6
K05443 IL10; interleukin 10
K04692 STAT3; signal transducer and activator of transcription 3
K04357 EGF; epidermal growth factor
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K11434 PRMT1; type I protein arginine methyltransferase [EC:2.1.1.319]
K09385 FOXG; forkhead box protein G
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K21771 CCNB3; G2/mitotic-specific cyclin-B3
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10146 CCNG2; cyclin G2
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K16332 RBL2; retinoblastoma-like protein 2
K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
K08861 PLK2; polo-like kinase 2 [EC:2.7.11.21]
K08862 PLK3; polo-like kinase 3 [EC:2.7.11.21]
K08863 PLK4; polo-like kinase 4 [EC:2.7.11.21]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K04721 TNFSF10; tumor necrosis factor ligand superfamily member 10
K15618 BCL6; B-cell lymphoma 6 protein
K15464 BNIP3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
K08336 ATG12; ubiquitin-like protein ATG12
K08341 GABARAP; GABA(A) receptor-associated protein
K08341 GABARAP; GABA(A) receptor-associated protein
K03781 katE; catalase [EC:1.11.1.6]
K04564 SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K05072 IL7R; interleukin 7 receptor
K17845 KLF2; krueppel-like factor 2
K04288 S1PR1; sphingosine 1-phosphate receptor 1
K04293 S1PR4; sphingosine 1-phosphate receptor 4
K10628 RAG1; V(D)J recombination-activating protein 1 [EC:2.3.2.27]
K10988 RAG2; recombination-activating protein 2
K10305 FBXO25_32; F-box protein 25/32
K10305 FBXO25_32; F-box protein 25/32
     04020 Calcium signaling pathway [PATH:fch04020]
     04070 Phosphatidylinositol signaling system [PATH:fch04070]
     04072 Phospholipase D signaling pathway
     04071 Sphingolipid signaling pathway
     04024 cAMP signaling pathway
     04022 cGMP-PKG signaling pathway
     04151 PI3K-Akt signaling pathway
     04152 AMPK signaling pathway
     04150 mTOR signaling pathway [PATH:fch04150]
     04075 Plant hormone signal transduction
 
   09133 Signaling molecules and interaction
 
 09140 Cellular Processes
 
   09141 Transport and catabolism
 
   09143 Cell growth and death
     04110 Cell cycle [PATH:fch04110]
       102053036 CCND1; G1/S-specific cyclin-D1
       102053549 CCND2; G1/S-specific cyclin-D2
       102059828 CCND3; G1/S-specific cyclin-D3 isoform X1
       102047555 CDK6; cyclin-dependent kinase 6
       102054877 RB1; retinoblastoma-associated protein
       102050265 RBL1; retinoblastoma-like protein 1 isoform X1
       102056460 RBL2; retinoblastoma-like protein 2 isoform X2
       102052443 ABL1; tyrosine-protein kinase ABL1 isoform X1
       102055405 HDAC1; histone deacetylase 1
       102057203 HDAC2; histone deacetylase 2
       102052559 E2F1; transcription factor E2F1
       102058355 E2F2; transcription factor E2F2 isoform X1
       102046119 E2F3; transcription factor E2F3 isoform X1
       102057067 E2F4; LOW QUALITY PROTEIN: transcription factor E2F4
       102057325 E2F5; transcription factor E2F5
       102048541 TFDP1; transcription factor Dp-1 isoform X2
       102054005 TFDP2; transcription factor Dp-2 isoform X2
       102059271 GSK3B; glycogen synthase kinase-3 beta isoform X1
       102047778 TGFB2; transforming growth factor beta-2 proprotein
       102055453 TGFB3; transforming growth factor beta-3 proprotein
       102059402 SMAD2; mothers against decapentaplegic homolog 2 isoform X1
       102053568 SMAD3; mothers against decapentaplegic homolog 3 isoform X1
       102057734 SMAD4; mothers against decapentaplegic homolog 4 isoform X1
       102048236 mothers against decapentaplegic homolog 4-like
       102056832 MYC; myc proto-oncogene protein
       102053344 ZBTB17; zinc finger and BTB domain-containing protein 17
       102051318 CDKN2C; cyclin-dependent kinase 4 inhibitor C
       102051672 CDKN1B; cyclin-dependent kinase inhibitor 1B
       114014226 CDKN1A; cyclin-dependent kinase inhibitor 1
       102059423 CCNE1; G1/S-specific cyclin-E1
       102047310 CCNE2; G1/S-specific cyclin-E2 isoform X2
       102046372 SKP1; S-phase kinase-associated protein 1
       102056187 CUL1; cullin-1
       102049129 RBX1; E3 ubiquitin-protein ligase RBX1
       102053148 SKP2; S-phase kinase-associated protein 2
       102057956 CCNA2; cyclin-A2
       102053902 CCNA1; cyclin-A1
       102055202 CDC6; cell division control protein 6 homolog
       102052346 CDT1; DNA replication factor Cdt1
       102060031 ORC1; origin recognition complex subunit 1
       102056946 origin recognition complex subunit 2 isoform X4
       102050146 ORC3; origin recognition complex subunit 3 isoform X6
       102053149 ORC4; origin recognition complex subunit 4
       102047368 ORC5; origin recognition complex subunit 5 isoform X1
       102053596 ORC6; origin recognition complex subunit 6
       102057606 MCM2; DNA replication licensing factor MCM2
       102051201 MCM3; DNA replication licensing factor MCM3
       102045846 MCM4; DNA replication licensing factor MCM4
       102055635 MCM5; DNA replication licensing factor MCM5
       102058582 MCM6; DNA replication licensing factor MCM6
       102047425 CDC45; cell division control protein 45 homolog
       102048649 TICRR; treslin
       102054568 mdm2-binding protein
       102047930 CDC7; cell division cycle 7-related protein kinase isoform X1
       102058120 DBF4; LOW QUALITY PROTEIN: protein DBF4 homolog A
       102049851 DBF4B; protein DBF4 homolog B isoform X1
       102058935 CDK1; cyclin-dependent kinase 1
       102046409 CCNB1; LOW QUALITY PROTEIN: G2/mitotic-specific cyclin-B1
       102054317 CCNB2; G2/mitotic-specific cyclin-B2
       102051864 CCNB3; G2/mitotic-specific cyclin-B3 isoform X1
       102053620 CDC25B; LOW QUALITY PROTEIN: M-phase inducer phosphatase 2
       102052519 YWHAQ; 14-3-3 protein theta
       102051367 YWHAB; 14-3-3 protein beta/alpha isoform X1
       102058855 YWHAZ; 14-3-3 protein zeta/delta
       102053007 YWHAE; 14-3-3 protein epsilon
       102057409 YWHAG; 14-3-3 protein gamma
       102053660 YWHAH; 14-3-3 protein eta
       102046673 PLK1; serine/threonine-protein kinase PLK1
       102055259 WEE2; wee1-like protein kinase 2
       102046610 WEE1; wee1-like protein kinase
       102046357 CCNH; cyclin-H
       102046068 CDK7; cyclin-dependent kinase 7 isoform X1
       102058801 ANAPC1; LOW QUALITY PROTEIN: anaphase-promoting complex subunit 1
       102059245 ANAPC2; anaphase-promoting complex subunit 2
       102047112 CDC27; cell division cycle protein 27 homolog isoform X2
       102056193 ANAPC4; anaphase-promoting complex subunit 4 isoform X1
       102050436 ANAPC5; anaphase-promoting complex subunit 5
       102051139 CDC16; cell division cycle protein 16 homolog isoform X1
       102049913 ANAPC7; anaphase-promoting complex subunit 7
       102046316 CDC23; cell division cycle protein 23 homolog
       102060033 ANAPC10; anaphase-promoting complex subunit 10
       102050582 ANAPC13; anaphase-promoting complex subunit 13
       102057326 ANAPC15; anaphase-promoting complex subunit 15 isoform X1
       102053271 ANAPC16; anaphase-promoting complex subunit 16
       102054040 CDC20; cell division cycle protein 20 homolog
       102047993 PTTG1; securin isoform X1
       102059227 ESPL1; separin
       102050629 SMC1B; structural maintenance of chromosomes protein 1B isoform X1
       102048613 SMC3; structural maintenance of chromosomes protein 3
       102049423 RAD21; double-strand-break repair protein rad21 homolog isoform X1
       102057979 cohesin subunit SA-2-like isoform X1
       102049248 STAG1; cohesin subunit SA-1 isoform X2
       102051249 STAG2; cohesin subunit SA-2 isoform X1
       102056585 ATRX; transcriptional regulator ATRX
       102055609 DDX11; ATP-dependent DNA helicase DDX11
       102053499 NIPBL; LOW QUALITY PROTEIN: nipped-B-like protein
       102058971 MAU2; MAU2 chromatid cohesion factor homolog
       102050152 HDAC8; histone deacetylase 8
       102048386 ESCO2; N-acetyltransferase ESCO2 isoform X1
       102053832 ESCO1; N-acetyltransferase ESCO1 isoform X2
       102052928 PDS5A; sister chromatid cohesion protein PDS5 homolog A isoform X1
       102045767 PDS5B; sister chromatid cohesion protein PDS5 homolog B isoform X1
       102060116 WAPL; wings apart-like protein homolog isoform X1
       102057582 SGO1; shugoshin 1
       102052989 PPP2CB; serine/threonine-protein phosphatase 2A catalytic subunit beta isoform
       102058381 PPP2CA; serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
       102056197 PPP2R1A; serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
       102057631 PPP2R5E; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform isoform X3
       102055426 PPP2R5C; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X1
       102053998 PPP2R5A; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform
       102059701 PPP2R5D; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform
       102050225 NDC80; kinetochore protein NDC80 homolog
       102048828 KNL1; LOW QUALITY PROTEIN: kinetochore scaffold 1
       102055530 TTK; dual specificity protein kinase TTK
       102057977 MAD1L1; mitotic spindle assembly checkpoint protein MAD1 isoform X1
       102057276 MAD2L1; mitotic spindle assembly checkpoint protein MAD2A
       102052591 MAD2L2; mitotic spindle assembly checkpoint protein MAD2B
       102047575 BUB1B; mitotic checkpoint serine/threonine-protein kinase BUB1 beta isoform X1
       102047407 BUB3; mitotic checkpoint protein BUB3 isoform X2
       102052065 BUB1; mitotic checkpoint serine/threonine-protein kinase BUB1
       102053645 TRIP13; pachytene checkpoint protein 2 homolog isoform X1
       102053233 MAD2L1BP; MAD2L1-binding protein
       102060120 FZR1; fizzy-related protein homolog
       102045723 FBXO5; F-box only protein 5
       102050084 CDC14A; dual specificity protein phosphatase CDC14A isoform X3
       102056690 CDC14B; dual specificity protein phosphatase CDC14B isoform X1
       102056653 CREBBP; LOW QUALITY PROTEIN: CREB-binding protein
       102045802 EP300; histone acetyltransferase p300 isoform X2
       102045681 PRKDC; DNA-dependent protein kinase catalytic subunit
       102049948 ATR; serine/threonine-protein kinase ATR
       102058832 ATM; serine-protein kinase ATM
       102048171 MDM2; E3 ubiquitin-protein ligase Mdm2 isoform X1
       102057224 GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma
       102057932 GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta
       102055712 PCNA; proliferating cell nuclear antigen
       102050727 SFN; 14-3-3 protein sigma
       102048652 CHEK1; LOW QUALITY PROTEIN: serine/threonine-protein kinase Chk1
       102057640 CHEK2; serine/threonine-protein kinase Chk2
       102054923 CDC25A; M-phase inducer phosphatase 1
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K04681 RBL1; retinoblastoma-like protein 1
K16332 RBL2; retinoblastoma-like protein 2
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04682 E2F4_5; transcription factor E2F4/5
K04682 E2F4_5; transcription factor E2F4/5
K04683 TFDP1; transcription factor Dp-1
K09392 TFDP2; transcription factor Dp-2
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04377 MYC; Myc proto-oncogene protein
K10500 ZBTB17; zinc finger and BTB domain-containing protein 17
K06622 CDKN2C; cyclin-dependent kinase inhibitor 2C
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K03094 SKP1; S-phase kinase-associated protein 1
K03347 CUL1; cullin 1
K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K02213 CDC6; cell division control protein 6
K10727 CDT1; chromatin licensing and DNA replication factor 1
K02603 ORC1; origin recognition complex subunit 1
K02604 ORC2; origin recognition complex subunit 2
K02605 ORC3; origin recognition complex subunit 3
K02606 ORC4; origin recognition complex subunit 4
K02607 ORC5; origin recognition complex subunit 5
K02608 ORC6; origin recognition complex subunit 6
K02540 MCM2; DNA replication licensing factor MCM2 [EC:5.6.2.3]
K02541 MCM3; DNA replication licensing factor MCM3 [EC:5.6.2.3]
K02212 MCM4; DNA replication licensing factor MCM4 [EC:5.6.2.3]
K02209 MCM5; DNA replication licensing factor MCM5 [EC:5.6.2.3]
K02542 MCM6; DNA replication licensing factor MCM6 [EC:5.6.2.3]
K06628 CDC45; cell division control protein 45
K26117 TICRR; Treslin
K26116 MTBP; Mdm2-binding protein
K02214 CDC7; cell division control protein 7 [EC:2.7.11.1]
K06629 DBF4; protein DBF4
K06629 DBF4; protein DBF4
K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K21771 CCNB3; G2/mitotic-specific cyclin-B3
K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K06630 YWHAE; 14-3-3 protein epsilon
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
K06634 CCNH; cyclin H
K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
K03348 APC1; anaphase-promoting complex subunit 1
K03349 APC2; anaphase-promoting complex subunit 2
K03350 APC3; anaphase-promoting complex subunit 3
K03351 APC4; anaphase-promoting complex subunit 4
K03352 APC5; anaphase-promoting complex subunit 5
K03353 APC6; anaphase-promoting complex subunit 6
K03354 APC7; anaphase-promoting complex subunit 7
K03355 APC8; anaphase-promoting complex subunit 8
K03357 APC10; anaphase-promoting complex subunit 10
K12456 APC13; anaphase-promoting complex subunit 13
K25228 APC15; anaphase-promoting complex subunit 15
K25229 APC16; anaphase-promoting complex subunit 16
K03363 CDC20; cell division cycle 20, cofactor of APC complex
K06635 PTTG; securin
K02365 ESP1; separase [EC:3.4.22.49]
K06636 SMC1; structural maintenance of chromosome 1
K06669 SMC3; structural maintenance of chromosome 3 (chondroitin sulfate proteoglycan 6)
K06670 SCC1; cohesin complex subunit SCC1
K06671 STAG1_2; cohesin complex subunit SA-1/2
K06671 STAG1_2; cohesin complex subunit SA-1/2
K06671 STAG1_2; cohesin complex subunit SA-1/2
K10779 ATRX; transcriptional regulator ATRX
K11273 DDX11; chromosome transmission fidelity protein 1 [EC:5.6.2.7]
K06672 SCC2; cohesin loading factor subunit SCC2
K11266 MAU2; MAternally affected uncoordination
K11405 HDAC8; histone deacetylase 8 [EC:3.5.1.98]
K11268 ESCO; N-acetyltransferase [EC:2.3.1.-]
K11268 ESCO; N-acetyltransferase [EC:2.3.1.-]
K11267 PDS5; sister chromatid cohesion protein PDS5
K11267 PDS5; sister chromatid cohesion protein PDS5
K25163 WAPL; wings apart-like protein
K11580 SGOL1; shugoshin-like 1
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11547 NDC80; kinetochore protein NDC80
K11542 CASC5; protein CASC5
K08866 TTK; serine/threonine-protein kinase TTK/MPS1 [EC:2.7.12.1]
K06679 MAD1; mitotic spindle assembly checkpoint protein MAD1
K02537 MAD2; mitotic spindle assembly checkpoint protein MAD2
K13728 MAD2L2; mitotic spindle assembly checkpoint protein MAD2B
K06637 BUB1B; mitotic checkpoint serine/threonine-protein kinase BUB1 beta [EC:2.7.11.1]
K02180 BUB3; cell cycle arrest protein BUB3
K02178 BUB1; checkpoint serine/threonine-protein kinase [EC:2.7.11.1]
K22399 TRIP13; pachytene checkpoint protein 2
K26093 MAD2L1BP; MAD2L1-binding protein
K03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
K10292 FBXO5; F-box protein 5
K06639 CDC14; cell division cycle 14 [EC:3.1.3.16 3.1.3.48]
K06639 CDC14; cell division cycle 14 [EC:3.1.3.16 3.1.3.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04802 PCNA; proliferating cell nuclear antigen
K06644 SFN; stratifin
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
     04111 Cell cycle - yeast
     04112 Cell cycle - Caulobacter
     04113 Meiosis - yeast
     04114 Oocyte meiosis [PATH:fch04114]
     04210 Apoptosis [PATH:fch04210]
     04214 Apoptosis - fly
     04215 Apoptosis - multiple species
     04216 Ferroptosis [PATH:fch04216]
     04217 Necroptosis [PATH:fch04217]
     04115 p53 signaling pathway [PATH:fch04115]
       102058832 ATM; serine-protein kinase ATM
       102057640 CHEK2; serine/threonine-protein kinase Chk2
       102049948 ATR; serine/threonine-protein kinase ATR
       102048652 CHEK1; LOW QUALITY PROTEIN: serine/threonine-protein kinase Chk1
       102048302 GORAB; LOW QUALITY PROTEIN: RAB6-interacting golgin
       102048171 MDM2; E3 ubiquitin-protein ligase Mdm2 isoform X1
       102047084 MDM4; protein Mdm4
       114014226 CDKN1A; cyclin-dependent kinase inhibitor 1
       102053036 CCND1; G1/S-specific cyclin-D1
       102053549 CCND2; G1/S-specific cyclin-D2
       102059828 CCND3; G1/S-specific cyclin-D3 isoform X1
       102047555 CDK6; cyclin-dependent kinase 6
       102059423 CCNE1; G1/S-specific cyclin-E1
       102047310 CCNE2; G1/S-specific cyclin-E2 isoform X2
       102050727 SFN; 14-3-3 protein sigma
       102046409 CCNB1; LOW QUALITY PROTEIN: G2/mitotic-specific cyclin-B1
       102054317 CCNB2; G2/mitotic-specific cyclin-B2
       102058935 CDK1; cyclin-dependent kinase 1
       102057224 GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma
       102057932 GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta
       102049791 GTSE1; G2 and S phase-expressed protein 1 isoform X1
       102048640 FAS; tumor necrosis factor receptor superfamily member 6
       102060037 PIDD1; p53-induced death domain-containing protein 1 isoform X1
       102053169 tumor necrosis factor receptor superfamily member 10A
       106630990 CASP8; caspase-8 isoform X1
       102053879 BID; BH3-interacting domain death agonist isoform X1
       102056509 BCL2L1; bcl-2-like protein 1
       102056589 BCL2; apoptosis regulator Bcl-2
       102059923 TP53I3; quinone oxidoreductase PIG3 isoform X1
       102055873 EI24; etoposide-induced protein 2.4 homolog
       102057660 LOW QUALITY PROTEIN: protein shisa-5-like
       102046643 p53 apoptosis effector related to PMP-22-like
       102046813 p53 apoptosis effector related to PMP-22-like
       102048902 ZMAT3; zinc finger matrin-type protein 3
       102058058 SIAH1; E3 ubiquitin-protein ligase SIAH1 isoform X2
       102046053 cytochrome c
       102046505 APAF1; apoptotic protease-activating factor 1 isoform X1
       102054465 CASP9; caspase-9 isoform X2
       102056397 CASP3; caspase-3
       102057106 AIFM2; apoptosis-inducing factor 2
       102056357 IGFBP3; insulin-like growth factor-binding protein 3
       102060062 IGF1; insulin-like growth factor I
       102054251 CD82; CD82 antigen
       102054866 THBS1; thrombospondin-1
       102056758 SERPINB5; serpin B5
       102048021 DDB2; DNA damage-binding protein 2 isoform X1
       102056241 RRM2; LOW QUALITY PROTEIN: ribonucleoside-diphosphate reductase subunit M2
       102054305 RRM2B; ribonucleoside-diphosphate reductase subunit M2 B
       102051859 sestrin-3-like isoform X1
       102048373 SESN3; sestrin-3 isoform X2
       102059656 SESN1; sestrin-1 isoform X2
       102055687 SESN2; sestrin-2 isoform X1
       102050194 PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1
       102055452 TSC2; tuberin isoform X4
       102047261 STEAP3; metalloreductase STEAP3 isoform X1
       102057361 COP1; E3 ubiquitin-protein ligase COP1 isoform X2
       102052138 RCHY1; RING finger and CHY zinc finger domain-containing protein 1
       102048798 CCNG1; cyclin-G1
       102054033 CCNG2; cyclin-G2
       102056834 PPM1D; protein phosphatase 1D
       102059062 TP73; tumor protein p73 isoform X2
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K19748 GORAB; RAB6-interacting golgin
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K10127 MDM4; protein Mdm4
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K06644 SFN; stratifin
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K10129 GTSE1; G-2 and S-phase expressed protein 1
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K10130 LRDD; leucine-rich repeats and death domain-containing protein
K04722 TNFRSF10A_B; tumor necrosis factor receptor superfamily member 10A/B
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator Bcl-2
K10133 TP53I3; tumor protein p53-inducible protein 3 [EC:1.-.-.-]
K10134 EI24; etoposide-induced 2.4 mRNA
K10135 SCOTIN; scotin
K10136 PERP; TP53 apoptosis effector
K10136 PERP; TP53 apoptosis effector
K10137 ZMAT3; zinc finger, matrin type 3
K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K22745 AIFM2; apoptosis-inducing factor 2
K10138 IGFBP3; insulin-like growth factor-binding protein 3
K05459 IGF1; insulin-like growth factor 1
K06509 KAI1; CD82 antigen
K16857 THBS1; thrombospondin 1
K10139 SERPINB5; serpin B5
K10140 DDB2; DNA damage-binding protein 2
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K10141 SESN1_3; sestrin 1/3
K10141 SESN1_3; sestrin 1/3
K10141 SESN1_3; sestrin 1/3
K20394 SESN2; sestrin 2
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K07207 TSC2; tuberous sclerosis 2
K10142 STEAP3; metalloreductase STEAP3 [EC:1.16.1.-]
K10143 RFWD2; E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]
K10144 RCHY1; RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]
K10145 CCNG1; cyclin G1
K10146 CCNG2; cyclin G2
K10147 PPM1D; protein phosphatase 1D [EC:3.1.3.16]
K10148 TP73; tumor protein p73
     04218 Cellular senescence [PATH:fch04218]
       102047778 TGFB2; transforming growth factor beta-2 proprotein
       102055453 TGFB3; transforming growth factor beta-3 proprotein
       102055038 TGFBR1; TGF-beta receptor type-1
       102048632 TGF-beta receptor type-2-like
       102053489 TGFBR2; TGF-beta receptor type-2
       102059402 SMAD2; mothers against decapentaplegic homolog 2 isoform X1
       102053568 SMAD3; mothers against decapentaplegic homolog 3 isoform X1
       102047555 CDK6; cyclin-dependent kinase 6
       102053036 CCND1; G1/S-specific cyclin-D1
       102053549 CCND2; G1/S-specific cyclin-D2
       102059828 CCND3; G1/S-specific cyclin-D3 isoform X1
       102054877 RB1; retinoblastoma-associated protein
       102050265 RBL1; retinoblastoma-like protein 1 isoform X1
       102056460 RBL2; retinoblastoma-like protein 2 isoform X2
       102052559 E2F1; transcription factor E2F1
       102058355 E2F2; transcription factor E2F2 isoform X1
       102046119 E2F3; transcription factor E2F3 isoform X1
       102057067 E2F4; LOW QUALITY PROTEIN: transcription factor E2F4
       102057325 E2F5; transcription factor E2F5
       102049812 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
       102057414 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
       102049197 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
       102056135 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1
       102059517 phosphatidylinositol 3-kinase regulatory subunit gamma isoform X2
       102057083 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta
       102057600 FOXO1; forkhead box protein O1
       102052285 FOXO3; forkhead box protein O3 isoform X1
       114014226 CDKN1A; cyclin-dependent kinase inhibitor 1
       102059423 CCNE1; G1/S-specific cyclin-E1
       102047310 CCNE2; G1/S-specific cyclin-E2 isoform X2
       102052019 KRAS; GTPase KRas isoform X1
       102054942 NRAS; GTPase NRas
       102050700 RRAS2; ras-related protein R-Ras2 isoform X1
       102047148 MRAS; ras-related protein M-Ras
       102055506 HRAS; GTPase HRas
       102060018 AKT2; RAC-beta serine/threonine-protein kinase
       102055811 AKT1; RAC-alpha serine/threonine-protein kinase
       102050094 AKT3; RAC-gamma serine/threonine-protein kinase isoform X1
       102050812 TSC1; hamartin isoform X1
       102055452 TSC2; tuberin isoform X4
       102048263 RHEB; GTP-binding protein Rheb
       102051979 MTOR; serine/threonine-protein kinase mTOR
       102050194 PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1
       102058467 SIRT1; NAD-dependent protein deacetylase sirtuin-1
       102057956 CCNA2; cyclin-A2
       102053902 CCNA1; cyclin-A1
       102051208 MYBL2; myb-related protein B
       102059362 LIN9; protein lin-9 homolog isoform X2
       102046900 LIN52; protein lin-52 homolog
       102056078 LIN54; protein lin-54 homolog isoform X2
       102053610 RBBP4; histone-binding protein RBBP4
       102050879 FOXM1; LOW QUALITY PROTEIN: forkhead box protein M1
       102056832 MYC; myc proto-oncogene protein
       102048171 MDM2; E3 ubiquitin-protein ligase Mdm2 isoform X1
       102051790 RASSF5; ras association domain-containing protein 5
       102054729 BTRC; F-box/WD repeat-containing protein 1A isoform X1
       102057588 FBXW11; F-box/WD repeat-containing protein 11
       102049832 HIPK3; homeodomain-interacting protein kinase 3 isoform X2
       102048007 HIPK2; homeodomain-interacting protein kinase 2 isoform X1
       102045853 HIPK4; homeodomain-interacting protein kinase 4
       102054129 HIPK1; LOW QUALITY PROTEIN: homeodomain-interacting protein kinase 1
       102058478 PPP1CB; serine/threonine-protein phosphatase PP1-beta catalytic subunit
       102054093 serine/threonine-protein phosphatase PP1-gamma catalytic subunit
       102053170 PPP1CA; serine/threonine-protein phosphatase PP1-alpha catalytic subunit
       102051503 RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1
       102053397 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X1
       102049695 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2
       102048221 MAPK1; LOW QUALITY PROTEIN: mitogen-activated protein kinase 1
       102055484 ETS1; protein C-ets-1
       102052703 MAP2K3; LOW QUALITY PROTEIN: dual specificity mitogen-activated protein kinase kinase 3
       102053088 MAP2K6; dual specificity mitogen-activated protein kinase kinase 6
       102059377 MAPK14; mitogen-activated protein kinase 14 isoform X1
       102054359 MAPK13; mitogen-activated protein kinase 13 isoform X1
       102051874 MAPK12; mitogen-activated protein kinase 12 isoform X1
       102052038 MAPK11; mitogen-activated protein kinase 11
       102057224 GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma
       102057932 GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta
       102058935 CDK1; cyclin-dependent kinase 1
       102046409 CCNB1; LOW QUALITY PROTEIN: G2/mitotic-specific cyclin-B1
       102054317 CCNB2; G2/mitotic-specific cyclin-B2
       102051864 CCNB3; G2/mitotic-specific cyclin-B3 isoform X1
       102045904 MRE11; double-strand break repair protein MRE11
       102048259 RAD50; DNA repair protein RAD50
       102056294 NBN; nibrin
       102058832 ATM; serine-protein kinase ATM
       102057640 CHEK2; serine/threonine-protein kinase Chk2
       102053001 RAD9A; cell cycle checkpoint control protein RAD9A isoform X1
       102054440 RAD9B; cell cycle checkpoint control protein RAD9B isoform X5
       102052130 RAD1; cell cycle checkpoint protein RAD1
       102057893 HUS1; checkpoint protein HUS1
       102049948 ATR; serine/threonine-protein kinase ATR
       102048652 CHEK1; LOW QUALITY PROTEIN: serine/threonine-protein kinase Chk1
       102054923 CDC25A; M-phase inducer phosphatase 1
       102053934 SQSTM1; sequestosome-1 isoform X1
       102060092 GATA4; transcription factor GATA-4 isoform X2
       102057938 TRAF3IP2; adapter protein CIKS isoform X1
       102049462 NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1
       102047657 IL6; interleukin-6
       102051634 interleukin-8
       102056940 interleukin-8-like
       102056357 IGFBP3; insulin-like growth factor-binding protein 3
       102047520 EIF4EBP1; eukaryotic translation initiation factor 4E-binding protein 1
       102050830 MAPKAPK2; MAP kinase-activated protein kinase 2 isoform X3
       102048200 ZFP36L1; mRNA decay activator protein ZFP36L1
       102054190 CACNA1D; LOW QUALITY PROTEIN: voltage-dependent L-type calcium channel subunit alpha-1D
       102051043 TRPV4; transient receptor potential cation channel subfamily V member 4
       114015105 transient receptor potential cation channel subfamily M member 7-like
       102045859 CAPN11; calpain-11
       102058565 CAPN1; calpain-1 catalytic subunit
       102048431 CAPN2; calpain-2 catalytic subunit
       102049588 CALM1; calmodulin-1
       102058651 CALM2; calmodulin-2
       102058709 calmodulin, striated muscle
       102055619 CALML4; calmodulin-like protein 4 isoform X1
       102052148 PPP3CC; serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform
       102048177 PPP3CB; serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X4
       102053077 PPP3CA; serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X1
       102050745 PPP3R1; calcineurin subunit B type 1 isoform X2
       102046809 NFATC1; nuclear factor of activated T-cells, cytoplasmic 1
       102047550 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2 isoform X1
       102050007 NFATC3; nuclear factor of activated T-cells, cytoplasmic 3 isoform X1
       102050701 ITPR1; inositol 1,4,5-trisphosphate receptor type 1
       102052635 ITPR2; inositol 1,4,5-trisphosphate receptor type 2 isoform X1
       102057380 ITPR3; inositol 1,4,5-trisphosphate receptor type 3
       102052754 SLC25A5; ADP/ATP translocase 2
       102057129 SLC25A6; ADP/ATP translocase 3
       102056660 SLC25A4; ADP/ATP translocase 1
       102058611 SLC25A31; LOW QUALITY PROTEIN: ADP/ATP translocase 4
       102047522 PPID; peptidyl-prolyl cis-trans isomerase D
       102046544 VDAC1; voltage-dependent anion-selective channel protein 1 isoform X1
       102057472 VDAC2; voltage-dependent anion-selective channel protein 2
       102053808 VDAC3; voltage-dependent anion-selective channel protein 3 isoform X1
       102054547 MCU; calcium uniporter protein, mitochondrial
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K06618 RB1; retinoblastoma-associated protein
K04681 RBL1; retinoblastoma-like protein 1
K16332 RBL2; retinoblastoma-like protein 2
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04682 E2F4_5; transcription factor E2F4/5
K04682 E2F4_5; transcription factor E2F4/5
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K07201 FOXO1; forkhead box protein O1
K09408 FOXO3; forkhead box protein O3
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K07830 RRAS2; Ras-related protein R-Ras2
K07831 MRAS; Ras-related protein M-Ras
K02833 HRAS; GTPase HRas
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K07208 RHEB; Ras homolog enriched in brain
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K11411 SIRT1; NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K21769 MYBL2; myb-related protein B
K21773 LIN9; protein lin-9
K21775 LIN52; protein lin-52
K21776 LIN54; protein lin-54
K10752 RBBP4; histone-binding protein RBBP4
K09406 FOXM; forkhead box protein M
K04377 MYC; Myc proto-oncogene protein
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K08015 RASSF5; Ras association domain-containing protein 5
K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K02678 ETS1; C-ets-1
K04432 MAP2K3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K05868 CCNB1; G2/mitotic-specific cyclin-B1
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K21771 CCNB3; G2/mitotic-specific cyclin-B3
K10865 MRE11; double-strand break repair protein MRE11
K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
K10867 NBN; nibrin
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]
K10995 RAD9B; cell cycle checkpoint control protein RAD9B
K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
K10903 HUS1; HUS1 checkpoint protein
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
K14381 SQSTM1; sequestosome 1
K09183 GATA4; GATA-binding protein 4
K21124 TRAF3IP2; adaptor protein CIKS
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K05405 IL6; interleukin 6
K10030 IL8; interleukin 8
K10030 IL8; interleukin 8
K10138 IGFBP3; insulin-like growth factor-binding protein 3
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
K18753 ZFP36L; butyrate response factor
K04851 CACNA1D; voltage-dependent calcium channel L type alpha-1D
K04973 TRPV4; transient receptor potential cation channel subfamily V member 4
K04982 TRPM7; transient receptor potential cation channel subfamily M member 7 [EC:2.7.11.1]
K01367 CAPN1; calpain-1 [EC:3.4.22.52]
K01367 CAPN1; calpain-1 [EC:3.4.22.52]
K03853 CAPN2; calpain-2 [EC:3.4.22.53]
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3; nuclear factor of activated T-cells, cytoplasmic 3
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05864 PPID; peptidyl-prolyl isomerase D [EC:5.2.1.8]
K05862 VDAC1; voltage-dependent anion channel protein 1
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K20858 MCU; calcium uniporter protein, mitochondrial
 
   09144 Cellular community - eukaryotes
 
   09145 Cellular community - prokaryotes
 
   09142 Cell motility
 
 09150 Organismal Systems
 
 09160 Human Diseases
 
 09180 Brite Hierarchies
 
 09190 Not Included in Pathway or Brite

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: April 23, 2024