KEGG Orthology (KO) - Geospiza fortis (medium ground-finch)

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     KO
 09100 Metabolism
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
   09131 Membrane transport
 
   09132 Signal transduction
     02020 Two-component system
     04010 MAPK signaling pathway [PATH:gfr04010]
     04013 MAPK signaling pathway - fly
     04016 MAPK signaling pathway - plant
     04011 MAPK signaling pathway - yeast
     04012 ErbB signaling pathway [PATH:gfr04012]
       102034269 EGF; epidermal growth factor
       102032034 uncharacterized LOC102032034
       102040687 AREG; amphiregulin
       102045482 EGFR; epidermal growth factor receptor
       102032882 PLCG1; phospholipase C gamma 1
       102038983 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1-like
       102039725 PLCG2; phospholipase C gamma 2
       102036854 CAMK2G; calcium/calmodulin dependent protein kinase II gamma
       102040653 CAMK2A; calcium/calmodulin dependent protein kinase II alpha
       102031855 CAMK2D; calcium/calmodulin-dependent protein kinase type II delta chain
       102041076 CAMK2B; calcium/calmodulin dependent protein kinase II beta
       102043485 PRKCA; protein kinase C alpha
       102041922 PRKCB; protein kinase C beta
       102040754 protein kinase C gamma type-like
       102036440 CBL; Cbl proto-oncogene
       102033221 CBLB; Cbl proto-oncogene B
       102036670 STAT5B; signal transducer and activator of transcription 5B
       102044186 SRC; SRC proto-oncogene, non-receptor tyrosine kinase
       102043366 PTK2; protein tyrosine kinase 2
       102039553 CRKL; CRK like proto-oncogene, adaptor protein
       102040219 CRK; CRK proto-oncogene, adaptor protein
       102042232 ABL1; ABL proto-oncogene 1, non-receptor tyrosine kinase
       102041022 ABL2; ABL proto-oncogene 2, non-receptor tyrosine kinase
       102038661 NCK2; NCK adaptor protein 2
       102033628 PAK1; p21 (RAC1) activated kinase 1
       102034742 PAK2; p21 (RAC1) activated kinase 2
       102042620 PAK3; p21 (RAC1) activated kinase 3
       102033882 serine/threonine-protein kinase PAK 1-like
       102045516 PAK5; p21 (RAC1) activated kinase 5
       102033561 PAK6; p21 (RAC1) activated kinase 6
       102037348 MAP2K4; mitogen-activated protein kinase kinase 4
       102038813 MAP2K7; mitogen-activated protein kinase kinase 7
       102036009 MAPK8; mitogen-activated protein kinase 8
       102043776 MAPK10; mitogen-activated protein kinase 10
       102043222 MAPK9; mitogen-activated protein kinase 9
       102039078 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
       102041705 BTC; betacellulin
       102031792 HBEGF; heparin binding EGF like growth factor
       102038525 EREG; epiregulin
       102041971 NRG1; neuregulin 1
       102032122 NRG2; neuregulin 2
       102045033 ERBB4; erb-b2 receptor tyrosine kinase 4
       102039503 SHC1; SHC adaptor protein 1
       102034643 SHC2; SHC adaptor protein 2
       102039603 SHC3; SHC adaptor protein 3
       102037367 SHC4; SHC adaptor protein 4
       102038068 GRB2; growth factor receptor bound protein 2
       102038427 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
       102033314 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
       102044012 HRAS; HRas proto-oncogene, GTPase
       102035876 KRAS; KRAS proto-oncogene, GTPase
       102039955 NRAS; neuroblastoma RAS viral oncogene homolog
       102032961 BRAF; B-Raf proto-oncogene, serine/threonine kinase
       102034977 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
       102031727 MAP2K1; mitogen-activated protein kinase kinase 1
       102041148 MAP2K2; mitogen-activated protein kinase kinase 2
       102043401 MAPK1; mitogen-activated protein kinase 1
       102039834 GAB1; GRB2 associated binding protein 1
       102039460 NRG3; neuregulin 3
       102032707 NRG4; neuregulin 4
       102042284 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       102040845 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       102040853 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       102039817 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
       102032353 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
       102035891 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
       102036745 AKT1; AKT serine/threonine kinase 1
       102036791 AKT3; AKT serine/threonine kinase 3
       102034190 MTOR; mechanistic target of rapamycin
       102036821 RPS6KB1; ribosomal protein S6 kinase B1
       102034944 GSK3B; glycogen synthase kinase 3 beta
       102045566 CDKN1B; cyclin dependent kinase inhibitor 1B
       102041135 CDKN1A; cyclin dependent kinase inhibitor 1A
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K09782 AREG; amphiregulin
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K22517 CBLB; E3 ubiquitin-protein ligase CBL-B [EC:2.3.2.27]
K11224 STAT5B; signal transducer and activator of transcription 5B
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K08887 ABL2; abelson tyrosine-protein kinase 2 [EC:2.7.10.2]
K19862 NCK2; NCK adaptor protein 2
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3; p21-activated kinase 3 [EC:2.7.11.1]
K05733 PAK3; p21-activated kinase 3 [EC:2.7.11.1]
K05736 PAK5; p21-activated kinase 5 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K04430 MAP2K4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K09783 BTC; betacellulin
K08523 HBEGF; heparin-binding EGF-like growth factor
K09784 EREG; epiregulin
K05455 NRG1; neuregulin 1
K05456 NRG2; neuregulin 2
K05085 ERBB4; receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K09593 GAB1; GRB2-associated-binding protein 1
K05457 NRG3; neuregulin 3
K05458 NRG4; neuregulin 4
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
     04014 Ras signaling pathway
     04015 Rap1 signaling pathway
     04310 Wnt signaling pathway [PATH:gfr04310]
     04330 Notch signaling pathway [PATH:gfr04330]
     04340 Hedgehog signaling pathway [PATH:gfr04340]
     04341 Hedgehog signaling pathway - fly
     04350 TGF-beta signaling pathway [PATH:gfr04350]
     04390 Hippo signaling pathway
     04391 Hippo signaling pathway - fly
     04392 Hippo signaling pathway - multiple species
     04370 VEGF signaling pathway [PATH:gfr04370]
     04371 Apelin signaling pathway [PATH:gfr04371]
     04630 JAK-STAT signaling pathway
     04064 NF-kappa B signaling pathway
     04668 TNF signaling pathway
     04066 HIF-1 signaling pathway
     04068 FoxO signaling pathway [PATH:gfr04068]
       102037698 TGFB2; transforming growth factor beta 2
       102037028 TGFB3; transforming growth factor beta 3
       102037879 TGFBR1; transforming growth factor beta receptor 1
       102044945 TGF-beta receptor type-2-like
       102040558 TGFBR2; transforming growth factor beta receptor 2
       102041942 mothers against decapentaplegic homolog 4-like
       102043998 SMAD4; SMAD family member 4
       102040325 SMAD3; SMAD family member 3
       102045531 STK11; serine/threonine kinase 11
       102044941 5'-AMP-activated protein kinase catalytic subunit alpha-1
       102038682 PRKAA1; protein kinase AMP-activated catalytic subunit alpha 1
       102031783 PRKAA2; protein kinase AMP-activated catalytic subunit alpha 2
       102045511 PRKAB1; protein kinase AMP-activated non-catalytic subunit beta 1
       102039548 PRKAB2; protein kinase AMP-activated non-catalytic subunit beta 2
       102035320 PRKAG3; protein kinase AMP-activated non-catalytic subunit gamma 3
       102042687 PRKAG2; protein kinase AMP-activated non-catalytic subunit gamma 2
       102033868 PRKAG1; protein kinase AMP-activated non-catalytic subunit gamma 1
       102033058 NLK; nemo like kinase
       102037500 SKP2; S-phase kinase associated protein 2
       102041787 MDM2; MDM2 proto-oncogene
       102040515 SETD7; SET domain containing lysine methyltransferase 7
       102038495 EP300; E1A binding protein p300
       102043483 CREBBP; CREB binding protein
       102038978 SIRT1; sirtuin 1
       102042457 USP7; ubiquitin specific peptidase 7
       102036009 MAPK8; mitogen-activated protein kinase 8
       102043776 MAPK10; mitogen-activated protein kinase 10
       102043222 MAPK9; mitogen-activated protein kinase 9
       102031383 STK4; serine/threonine kinase 4
       102032215 IGF1; insulin like growth factor 1
       102036037 IGF1R; insulin like growth factor 1 receptor
       102044590 INS; insulin
       102036061 INSR; insulin receptor
       102044407 IRS1; insulin receptor substrate 1
       102041556 IRS4; insulin receptor substrate 4
       102044059 IRS2; insulin receptor substrate 2
       102042284 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       102040845 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       102040853 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       102039817 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
       102032353 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
       102035891 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
       102032960 PDPK1; 3-phosphoinositide dependent protein kinase 1
       102042264 CHUK; conserved helix-loop-helix ubiquitous kinase
       102035648 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
       102039901 PTEN; phosphatase and tensin homolog
       102036745 AKT1; AKT serine/threonine kinase 1
       102036791 AKT3; AKT serine/threonine kinase 3
       102037330 SGK1; serum/glucocorticoid regulated kinase 1
       102031612 SGK2; SGK2, serine/threonine kinase 2
       102036813 SGK3; serine/threonine-protein kinase Sgk3
       102039410 FOXO1; forkhead box O1
       102034329 FOXO3; forkhead box O3
       102043730 FOXO4; forkhead box O4
       102031516 forkhead box protein O6-like
       102038278 GRM1; glutamate metabotropic receptor 1
       102039525 HOMER2; homer scaffolding protein 2
       102044255 HOMER1; homer scaffolding protein 1
       102043767 HOMER3; homer scaffolding protein 3
       102035003 CSNK1E; casein kinase I isoform epsilon
       102040265 IL6; interleukin 6
       102044259 IL10; interleukin 10
       102036392 STAT3; signal transducer and activator of transcription 3
       102034269 EGF; epidermal growth factor
       102045482 EGFR; epidermal growth factor receptor
       102038068 GRB2; growth factor receptor bound protein 2
       102038427 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
       102033314 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
       102044012 HRAS; HRas proto-oncogene, GTPase
       102035876 KRAS; KRAS proto-oncogene, GTPase
       102039955 NRAS; neuroblastoma RAS viral oncogene homolog
       102032961 BRAF; B-Raf proto-oncogene, serine/threonine kinase
       102034977 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
       102031727 MAP2K1; mitogen-activated protein kinase kinase 1
       102041148 MAP2K2; mitogen-activated protein kinase kinase 2
       102043401 MAPK1; mitogen-activated protein kinase 1
       102043521 MAPK12; mitogen-activated protein kinase 12
       102038787 MAPK11; mitogen-activated protein kinase 11
       102044158 MAPK14; mitogen-activated protein kinase 14
       102042160 MAPK13; mitogen-activated protein kinase 13
       102037592 FOXG1; forkhead box G1
       102044449 CCNB2; cyclin B2
       102043430 CCNB3; G2/mitotic-specific cyclin-B3
       102042858 CCND1; cyclin D1
       102034688 CCND2; cyclin D2
       102045099 CCNG2; cyclin G2
       102041135 CDKN1A; cyclin dependent kinase inhibitor 1A
       102045566 CDKN1B; cyclin dependent kinase inhibitor 1B
       102044028 RBL2; RB transcriptional corepressor like 2
       102042745 PLK1; polo like kinase 1
       102035739 PLK2; polo like kinase 2
       102037104 PLK3; polo like kinase 3
       102034868 PLK4; polo like kinase 4
       102045588 FASLG; Fas ligand
       102042782 TNFSF10; tumor necrosis factor superfamily member 10
       102041209 BCL6; B-cell CLL/lymphoma 6
       102036777 BNIP3; BCL2 interacting protein 3
       106632024 BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like
       102043479 GABARAPL2; GABA type A receptor associated protein like 2
       102039558 GABARAPL1; GABA type A receptor associated protein like 1
       102031847 CAT; catalase
       102040279 SOD2; superoxide dismutase 2
       102035572 PCK1; phosphoenolpyruvate carboxykinase 1
       102043169 G6PC2; glucose-6-phosphatase catalytic subunit 2
       102041145 G6PC; glucose-6-phosphatase catalytic subunit
       102033898 IL7R; interleukin 7 receptor
       102032912 KLF2; Kruppel like factor 2
       102036533 S1PR1; sphingosine-1-phosphate receptor 1
       102033804 S1PR4; sphingosine-1-phosphate receptor 4
       102041505 RAG1; recombination activating 1
       102041336 RAG2; recombination activating 2
       102032001 FBXO32; F-box protein 32
       102040175 FBXO25; F-box protein 25
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04501 SMAD4; mothers against decapentaplegic homolog 4
K23605 SMAD3; mothers against decapentaplegic homolog 3
K07298 STK11; serine/threonine-protein kinase 11 [EC:2.7.11.1]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K04468 NLK; nemo like kinase [EC:2.7.11.24]
K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K11431 SETD7; [histone H3]-lysine4 N-methyltransferase [EC:2.1.1.364]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K11411 SIRT1; NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04411 STK4; serine/threonine kinase 4
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04526 INS; insulin
K04527 INSR; insulin receptor [EC:2.7.10.1]
K16172 IRS1; insulin receptor substrate 1
K07187 IRS2; insulin receptor substrate 2
K07187 IRS2; insulin receptor substrate 2
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K13302 SGK1; serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]
K13303 SGK2; serum/glucocorticoid-regulated kinase 2 [EC:2.7.11.1]
K13304 SGK3; serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1]
K07201 FOXO1; forkhead box protein O1
K09408 FOXO3; forkhead box protein O3
K12358 FOXO4; forkhead box protein O4
K17847 FOXO6; forkhead box protein O6
K04603 GRM1; metabotropic glutamate receptor 1
K15010 HOMER; homer
K15010 HOMER; homer
K15010 HOMER; homer
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K05405 IL6; interleukin 6
K05443 IL10; interleukin 10
K04692 STAT3; signal transducer and activator of transcription 3
K04357 EGF; epidermal growth factor
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K09385 FOXG; forkhead box protein G
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K21771 CCNB3; G2/mitotic-specific cyclin-B3
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10146 CCNG2; cyclin G2
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K16332 RBL2; retinoblastoma-like protein 2
K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
K08861 PLK2; polo-like kinase 2 [EC:2.7.11.21]
K08862 PLK3; polo-like kinase 3 [EC:2.7.11.21]
K08863 PLK4; polo-like kinase 4 [EC:2.7.11.21]
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K04721 TNFSF10; tumor necrosis factor ligand superfamily member 10
K15618 BCL6; B-cell lymphoma 6 protein
K15464 BNIP3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
K15464 BNIP3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
K08341 GABARAP; GABA(A) receptor-associated protein
K08341 GABARAP; GABA(A) receptor-associated protein
K03781 katE; catalase [EC:1.11.1.6]
K04564 SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K05072 IL7R; interleukin 7 receptor
K17845 KLF2; krueppel-like factor 2
K04288 S1PR1; sphingosine 1-phosphate receptor 1
K04293 S1PR4; sphingosine 1-phosphate receptor 4
K10628 RAG1; V(D)J recombination-activating protein 1 [EC:2.3.2.27]
K10988 RAG2; recombination-activating protein 2
K10305 FBXO25_32; F-box protein 25/32
K10305 FBXO25_32; F-box protein 25/32
     04020 Calcium signaling pathway [PATH:gfr04020]
     04070 Phosphatidylinositol signaling system [PATH:gfr04070]
     04072 Phospholipase D signaling pathway
     04071 Sphingolipid signaling pathway
     04024 cAMP signaling pathway
     04022 cGMP-PKG signaling pathway
     04151 PI3K-Akt signaling pathway
     04152 AMPK signaling pathway
     04150 mTOR signaling pathway [PATH:gfr04150]
     04075 Plant hormone signal transduction
 
   09133 Signaling molecules and interaction
 
 09140 Cellular Processes
 
   09141 Transport and catabolism
 
   09143 Cell growth and death
     04110 Cell cycle [PATH:gfr04110]
       102042858 CCND1; cyclin D1
       102034688 CCND2; cyclin D2
       102033692 CCND3; cyclin D3
       102034159 CDK6; cyclin dependent kinase 6
       102036868 RB1; RB transcriptional corepressor 1
       102034865 RBL1; RB transcriptional corepressor like 1
       102044028 RBL2; RB transcriptional corepressor like 2
       102042232 ABL1; ABL proto-oncogene 1, non-receptor tyrosine kinase
       102038486 HDAC2; histone deacetylase 2
       102045090 HDAC1; histone deacetylase 1
       102032688 E2F1; E2F transcription factor 1
       102036661 E2F2; transcription factor E2F2
       102039591 E2F3; E2F transcription factor 3
       102032445 E2F4; E2F transcription factor 4
       102037886 E2F5; E2F transcription factor 5
       102036523 TFDP1; transcription factor Dp-1
       102042356 TFDP2; transcription factor Dp-2
       102034944 GSK3B; glycogen synthase kinase 3 beta
       102037698 TGFB2; transforming growth factor beta 2
       102037028 TGFB3; transforming growth factor beta 3
       102040865 mothers against decapentaplegic homolog 2-like
       102044404 SMAD2; SMAD family member 2
       102040325 SMAD3; SMAD family member 3
       102041942 mothers against decapentaplegic homolog 4-like
       102043998 SMAD4; SMAD family member 4
       102035988 ZBTB17; zinc finger and BTB domain containing 17
       102034516 CDKN2C; cyclin dependent kinase inhibitor 2C
       102045566 CDKN1B; cyclin dependent kinase inhibitor 1B
       102041135 CDKN1A; cyclin dependent kinase inhibitor 1A
       102043017 CCNE2; cyclin E2
       102040569 CCNE1; cyclin E1
       102038546 SKP1; S-phase kinase associated protein 1
       102038503 CUL1; cullin 1
       102037823 RBX1; ring-box 1
       102037500 SKP2; S-phase kinase associated protein 2
       102043650 CCNA1; cyclin A1
       102032849 CCNA2; cyclin A2
       102033975 CDC6; cell division control protein 6 homolog
       102036886 CDT1; chromatin licensing and DNA replication factor 1
       102035920 ORC1; origin recognition complex subunit 1
       102034208 ORC2; origin recognition complex subunit 2
       102040713 ORC3; origin recognition complex subunit 3
       102039050 ORC4; origin recognition complex subunit 4
       102045639 ORC5; origin recognition complex subunit 5
       102041407 ORC6; origin recognition complex subunit 6
       102043349 MCM2; minichromosome maintenance complex component 2
       102044581 MCM3; minichromosome maintenance complex component 3
       102044176 MCM4; minichromosome maintenance complex component 4
       102032440 MCM5; minichromosome maintenance complex component 5
       102041085 MCM6; minichromosome maintenance complex component 6
       102033577 MCM7; minichromosome maintenance complex component 7
       102039928 CDC45; cell division cycle 45
       102036798 TICRR; TOPBP1 interacting checkpoint and replication regulator
       102035737 MTBP; MDM2 binding protein
       102044566 CDC7; cell division cycle 7
       102045619 DBF4; DBF4 zinc finger
       102034239 CDK1; cyclin dependent kinase 1
       102044449 CCNB2; cyclin B2
       102043430 CCNB3; G2/mitotic-specific cyclin-B3
       102043016 YWHAB; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
       102035632 YWHAZ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
       102033997 YWHAQ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
       102040391 YWHAE; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
       102035580 YWHAG; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
       102041653 YWHAH; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
       102042745 PLK1; polo like kinase 1
       102032459 WEE2; WEE1 homolog 2
       102044984 WEE1; WEE1 G2 checkpoint kinase
       102034871 CCNH; cyclin H
       102043443 CDK7; cyclin dependent kinase 7
       102042185 ANAPC1; anaphase promoting complex subunit 1
       102042636 ANAPC2; anaphase promoting complex subunit 2
       102033810 CDC27; cell division cycle 27
       102036004 ANAPC4; anaphase promoting complex subunit 4
       102044742 ANAPC5; anaphase promoting complex subunit 5
       102036977 CDC16; cell division cycle 16
       102043856 ANAPC7; anaphase promoting complex subunit 7
       102038213 CDC23; cell division cycle 23
       102040249 ANAPC10; anaphase promoting complex subunit 10
       102032785 ANAPC13; anaphase promoting complex subunit 13
       102032636 ANAPC15; anaphase promoting complex subunit 15
       102039157 ANAPC16; anaphase promoting complex subunit 16
       102042968 CDC20; cell division cycle 20
       102036459 PTTG1; pituitary tumor-transforming 1
       102044437 ESPL1; extra spindle pole bodies like 1, separase
       102044626 SMC1B; structural maintenance of chromosomes 1B
       102040587 SMC1A; structural maintenance of chromosomes 1A
       102035434 SMC3; structural maintenance of chromosomes 3
       102043624 RAD21; RAD21 cohesin complex component
       102035391 RAD21L1; RAD21 cohesin complex component like 1
       102034892 cohesin subunit SA-2-like
       102039753 STAG2; stromal antigen 2
       102031956 STAG1; stromal antigen 1
       102044208 ATRX; ATRX, chromatin remodeler
       102036358 DDX11; DEAD/H-box helicase 11
       102034854 NIPBL; NIPBL, cohesin loading factor
       102042933 nipped-B-like protein
       102032751 MAU2; MAU2 sister chromatid cohesion factor
       102043759 HDAC8; histone deacetylase 8
       102040994 ESCO1; establishment of sister chromatid cohesion N-acetyltransferase 1
       102039510 PDS5A; PDS5 cohesin associated factor A
       102041983 PDS5B; PDS5 cohesin associated factor B
       102033311 WAPL; WAPL cohesin release factor
       102042294 SGO1; shugoshin 1
       102036925 PPP2CA; protein phosphatase 2 catalytic subunit alpha
       102042538 PPP2CB; protein phosphatase 2 catalytic subunit beta
       102031820 PPP2R5C; protein phosphatase 2 regulatory subunit B'gamma
       102039573 PPP2R5E; protein phosphatase 2 regulatory subunit B'epsilon
       102041034 PPP2R5A; protein phosphatase 2 regulatory subunit B'alpha
       102035456 PPP2R5D; protein phosphatase 2 regulatory subunit B'delta
       102039575 NDC80; NDC80, kinetochore complex component
       106631942 KNL1; kinetochore scaffold 1
       102044289 TTK; TTK protein kinase
       102043620 MAD1L1; MAD1 mitotic arrest deficient like 1
       102034691 MAD2L1; MAD2 mitotic arrest deficient-like 1 (yeast)
       102033397 MAD2L2; MAD2 mitotic arrest deficient-like 2 (yeast)
       102045196 BUB1B; BUB1 mitotic checkpoint serine/threonine kinase B
       102040620 BUB3; BUB3, mitotic checkpoint protein
       102041853 BUB1; BUB1 mitotic checkpoint serine/threonine kinase
       102044684 TRIP13; thyroid hormone receptor interactor 13
       102043386 MAD2L1BP; MAD2L1 binding protein
       102033016 FZR1; fizzy/cell division cycle 20 related 1
       102037876 FBXO5; F-box protein 5
       102035794 CDC14A; exostosin-like 2
       102034637 CDC14B; cell division cycle 14B
       102038495 EP300; E1A binding protein p300
       102043483 CREBBP; CREB binding protein
       102042450 PRKDC; protein kinase, DNA-activated, catalytic polypeptide
       102032229 ATR; ATR serine/threonine kinase
       102041787 MDM2; MDM2 proto-oncogene
       102042764 PCNA; proliferating cell nuclear antigen
       102038349 SFN; stratifin
       102039036 CHEK1; checkpoint kinase 1
       102038788 CHEK2; checkpoint kinase 2
       102040683 CDC25A; cell division cycle 25A
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K04681 RBL1; retinoblastoma-like protein 1
K16332 RBL2; retinoblastoma-like protein 2
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04682 E2F4_5; transcription factor E2F4/5
K04682 E2F4_5; transcription factor E2F4/5
K04683 TFDP1; transcription factor Dp-1
K09392 TFDP2; transcription factor Dp-2
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04500 SMAD2; mothers against decapentaplegic homolog 2
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04501 SMAD4; mothers against decapentaplegic homolog 4
K10500 ZBTB17; zinc finger and BTB domain-containing protein 17
K06622 CDKN2C; cyclin-dependent kinase inhibitor 2C
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K03094 SKP1; S-phase kinase-associated protein 1
K03347 CUL1; cullin 1
K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K02213 CDC6; cell division control protein 6
K10727 CDT1; chromatin licensing and DNA replication factor 1
K02603 ORC1; origin recognition complex subunit 1
K02604 ORC2; origin recognition complex subunit 2
K02605 ORC3; origin recognition complex subunit 3
K02606 ORC4; origin recognition complex subunit 4
K02607 ORC5; origin recognition complex subunit 5
K02608 ORC6; origin recognition complex subunit 6
K02540 MCM2; DNA replication licensing factor MCM2 [EC:5.6.2.3]
K02541 MCM3; DNA replication licensing factor MCM3 [EC:5.6.2.3]
K02212 MCM4; DNA replication licensing factor MCM4 [EC:5.6.2.3]
K02209 MCM5; DNA replication licensing factor MCM5 [EC:5.6.2.3]
K02542 MCM6; DNA replication licensing factor MCM6 [EC:5.6.2.3]
K02210 MCM7; DNA replication licensing factor MCM7 [EC:5.6.2.3]
K06628 CDC45; cell division control protein 45
K26117 TICRR; Treslin
K26116 MTBP; Mdm2-binding protein
K02214 CDC7; cell division control protein 7 [EC:2.7.11.1]
K06629 DBF4; protein DBF4
K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
K21770 CCNB2; G2/mitotic-specific cyclin-B2
K21771 CCNB3; G2/mitotic-specific cyclin-B3
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K06630 YWHAE; 14-3-3 protein epsilon
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
K06634 CCNH; cyclin H
K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
K03348 APC1; anaphase-promoting complex subunit 1
K03349 APC2; anaphase-promoting complex subunit 2
K03350 APC3; anaphase-promoting complex subunit 3
K03351 APC4; anaphase-promoting complex subunit 4
K03352 APC5; anaphase-promoting complex subunit 5
K03353 APC6; anaphase-promoting complex subunit 6
K03354 APC7; anaphase-promoting complex subunit 7
K03355 APC8; anaphase-promoting complex subunit 8
K03357 APC10; anaphase-promoting complex subunit 10
K12456 APC13; anaphase-promoting complex subunit 13
K25228 APC15; anaphase-promoting complex subunit 15
K25229 APC16; anaphase-promoting complex subunit 16
K03363 CDC20; cell division cycle 20, cofactor of APC complex
K06635 PTTG; securin
K02365 ESP1; separase [EC:3.4.22.49]
K06636 SMC1; structural maintenance of chromosome 1
K06636 SMC1; structural maintenance of chromosome 1
K06669 SMC3; structural maintenance of chromosome 3 (chondroitin sulfate proteoglycan 6)
K06670 SCC1; cohesin complex subunit SCC1
K06670 SCC1; cohesin complex subunit SCC1
K06671 STAG1_2; cohesin complex subunit SA-1/2
K06671 STAG1_2; cohesin complex subunit SA-1/2
K06671 STAG1_2; cohesin complex subunit SA-1/2
K10779 ATRX; transcriptional regulator ATRX
K11273 DDX11; chromosome transmission fidelity protein 1 [EC:5.6.2.7]
K06672 SCC2; cohesin loading factor subunit SCC2
K06672 SCC2; cohesin loading factor subunit SCC2
K11266 MAU2; MAternally affected uncoordination
K11405 HDAC8; histone deacetylase 8 [EC:3.5.1.98]
K11268 ESCO; N-acetyltransferase [EC:2.3.1.-]
K11267 PDS5; sister chromatid cohesion protein PDS5
K11267 PDS5; sister chromatid cohesion protein PDS5
K25163 WAPL; wings apart-like protein
K11580 SGOL1; shugoshin-like 1
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11547 NDC80; kinetochore protein NDC80
K11542 CASC5; protein CASC5
K08866 TTK; serine/threonine-protein kinase TTK/MPS1 [EC:2.7.12.1]
K06679 MAD1; mitotic spindle assembly checkpoint protein MAD1
K02537 MAD2; mitotic spindle assembly checkpoint protein MAD2
K13728 MAD2L2; mitotic spindle assembly checkpoint protein MAD2B
K06637 BUB1B; mitotic checkpoint serine/threonine-protein kinase BUB1 beta [EC:2.7.11.1]
K02180 BUB3; cell cycle arrest protein BUB3
K02178 BUB1; checkpoint serine/threonine-protein kinase [EC:2.7.11.1]
K22399 TRIP13; pachytene checkpoint protein 2
K26093 MAD2L1BP; MAD2L1-binding protein
K03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
K10292 FBXO5; F-box protein 5
K06639 CDC14; cell division cycle 14 [EC:3.1.3.16 3.1.3.48]
K06639 CDC14; cell division cycle 14 [EC:3.1.3.16 3.1.3.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04802 PCNA; proliferating cell nuclear antigen
K06644 SFN; stratifin
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
     04111 Cell cycle - yeast
     04112 Cell cycle - Caulobacter
     04113 Meiosis - yeast
     04114 Oocyte meiosis [PATH:gfr04114]
     04210 Apoptosis [PATH:gfr04210]
     04214 Apoptosis - fly
     04215 Apoptosis - multiple species
     04216 Ferroptosis [PATH:gfr04216]
     04217 Necroptosis [PATH:gfr04217]
     04115 p53 signaling pathway [PATH:gfr04115]
     04218 Cellular senescence [PATH:gfr04218]
 
   09144 Cellular community - eukaryotes
 
   09145 Cellular community - prokaryotes
 
   09142 Cell motility
 
 09150 Organismal Systems
 
 09160 Human Diseases
 
 09180 Brite Hierarchies
 
 09190 Not Included in Pathway or Brite

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: April 25, 2024