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KO |
Eukaryotic type
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Sister chromatid cohesion proteins
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Meiosis-specific proteins
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Nucleosome assembly factors
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Histone modification proteins
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HATs (histone acetyltransferases)
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HAT complexes
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HDACs (histone deacetylases)
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HDAC complexes
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Sin3A-HDAC complex
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BRAF-HDAC complex
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REST complex
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109508297 rest; RE1-silencing transcription factor
109518234 sin3a; paired amphipathic helix protein Sin3a
109525885 paired amphipathic helix protein Sin3a-like isoform X1
109516888 sin3b; paired amphipathic helix protein Sin3b isoform X1
109514575 probable histone deacetylase 1-B
109520795 probable histone deacetylase 1-B isoform X1
109520565 rcor1; REST corepressor 1
109530811 rcor3; REST corepressor 3
109511880 rcor2; REST corepressor 2
109526830 kdm1a; lysine-specific histone demethylase 1A isoform X1
109508408 smarca4; transcription activator BRG1 isoform X1
109511342 transcription activator BRG1-like isoform X1
109510555 histone-lysine N-methyltransferase EHMT1-like isoform X1
109527076 histone-lysine N-methyltransferase EHMT1-like
109516321 ehmt2; histone-lysine N-methyltransferase EHMT2
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K09222 REST; RE1-silencing transcription factor
K11644 SIN3A; paired amphipathic helix protein Sin3a
K11644 SIN3A; paired amphipathic helix protein Sin3a
K23213 SIN3B; paired amphipathic helix protein Sin3b
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K11829 RCOR1; REST corepressor 1
K26242 RCOR2_3; REST corepressor 2/3
K26242 RCOR2_3; REST corepressor 2/3
K11450 KDM1A; [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase [EC:1.14.99.66]
K11647 SMARCA2_4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:5.6.2.-]
K11647 SMARCA2_4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:5.6.2.-]
K11420 EHMT; [histone H3]-lysine9 N-trimethyltransferase EHMT [EC:2.1.1.355]
K11420 EHMT; [histone H3]-lysine9 N-trimethyltransferase EHMT [EC:2.1.1.355]
K11420 EHMT; [histone H3]-lysine9 N-trimethyltransferase EHMT [EC:2.1.1.355]
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SHIP complex
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MiDAC complex
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SMART complex
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Other HDAC associated proteins
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HMTs (histone methyltransferases)
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HKMTs (histone lysine methyltransferases)
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109513128 histone-lysine N-methyltransferase ASH1L-like isoform X1
109521050 ash1l; histone-lysine N-methyltransferase ASH1L isoform X1
109532198 dot1l; histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
109510555 histone-lysine N-methyltransferase EHMT1-like isoform X1
109527076 histone-lysine N-methyltransferase EHMT1-like
109516321 ehmt2; histone-lysine N-methyltransferase EHMT2
109508596 histone-lysine N-methyltransferase EZH1-like isoform X1
109521815 ezh2; histone-lysine N-methyltransferase EZH2
109529394 kmt2a; histone-lysine N-methyltransferase 2A isoform X1
109531346 kmt2d; histone-lysine N-methyltransferase 2D isoform X1
109521240 histone-lysine N-methyltransferase 2C-like isoform X1
109526300 LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2C-like
109514546 histone-lysine N-methyltransferase 2A-like
109525616 kmt2b; histone-lysine N-methyltransferase 2B isoform X1
109530075 kmt2e; histone-lysine N-methyltransferase 2E
109515816 histone-lysine N-methyltransferase NSD2-like
109517985 uncharacterized protein LOC109517985 isoform X1
109520165 nsd2; histone-lysine N-methyltransferase NSD2
109525952 nsd3; histone-lysine N-methyltransferase NSD3 isoform X1
109529179 prdm2; PR domain zinc finger protein 2
109526575 PR domain zinc finger protein 2-like
109525487 mecom; MDS1 and EVI1 complex locus protein EVI1 isoform X1
109513448 prdm6; putative histone-lysine N-methyltransferase PRDM6
109513274 histone-lysine N-methyltransferase PRDM9-like isoform X1
109512673 znf488; zinc finger protein 488
109509808 PR domain zinc finger protein 8-like
109526896 prdm8; PR domain zinc finger protein 8
109509672 PR domain zinc finger protein 8-like
109520407 prdm12; PR domain zinc finger protein 12
109525307 PR domain zinc finger protein 12-like
109526576 prdm16; PR domain zinc finger protein 16 isoform X1
109531597 LOW QUALITY PROTEIN: histone-lysine N-methyltransferase SETD1A-like
109517174 setd1b; histone-lysine N-methyltransferase SETD1B isoform X1
109518019 setd2; histone-lysine N-methyltransferase SETD2 isoform X1
109510205 setd4; SET domain-containing protein 4
109531142 setd6; N-lysine methyltransferase SETD6 isoform X1
109529075 setd7; histone-lysine N-methyltransferase SETD7
109529122 N-lysine methyltransferase KMT5A-A-like isoform X1
109525154 N-lysine methyltransferase KMT5A-A-like
109522778 setdb1; histone-lysine N-methyltransferase SETDB1
109528432 histone-lysine N-methyltransferase SETDB2-like isoform X1
109521469 histone-lysine N-methyltransferase SETMAR
109527440 smyd1; histone-lysine N-methyltransferase SMYD1 isoform X1
109528434 smyd3; histone-lysine N-methyltransferase SMYD3 isoform X1
109518109 N-lysine methyltransferase SMYD2-B-like
109531565 smyd2; N-lysine methyltransferase SMYD2
109528227 suv39h1; histone-lysine N-methyltransferase SUV39H1
109514373 kmt5b; histone-lysine N-methyltransferase KMT5B
109527740 uncharacterized protein LOC109527740
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K06101 ASH1L; [histone H3]-lysine4 N-trimethyltransferase ASH1L [EC:2.1.1.354]
K06101 ASH1L; [histone H3]-lysine4 N-trimethyltransferase ASH1L [EC:2.1.1.354]
K11427 DOT1L; [histone H3]-lysine79 N-trimethyltransferase [EC:2.1.1.360]
K11420 EHMT; [histone H3]-lysine9 N-trimethyltransferase EHMT [EC:2.1.1.355]
K11420 EHMT; [histone H3]-lysine9 N-trimethyltransferase EHMT [EC:2.1.1.355]
K11420 EHMT; [histone H3]-lysine9 N-trimethyltransferase EHMT [EC:2.1.1.355]
K17451 EZH1; [histone H3]-lysine27 N-trimethyltransferase EZH1 [EC:2.1.1.356]
K11430 EZH2; [histone H3]-lysine27 N-trimethyltransferase EZH2 [EC:2.1.1.356]
K09186 MLL1; [histone H3]-lysine4 N-trimethyltransferase MLL1 [EC:2.1.1.354]
K09187 MLL2; [histone H3]-lysine4 N-trimethyltransferase MLL2 [EC:2.1.1.354]
K09188 MLL3; [histone H3]-lysine4 N-trimethyltransferase MLL3 [EC:2.1.1.354]
K09188 MLL3; [histone H3]-lysine4 N-trimethyltransferase MLL3 [EC:2.1.1.354]
K14959 MLL4; [histone H3]-lysine4 N-trimethyltransferase MLL4 [EC:2.1.1.354]
K14959 MLL4; [histone H3]-lysine4 N-trimethyltransferase MLL4 [EC:2.1.1.354]
K09189 MLL5; [histone H3]-lysine4 N-trimethyltransferase MLL5 [EC:2.1.1.354]
K15588 NSD1; [histone H3]-lysine36 N-dimethyltransferase NSD1 [EC:2.1.1.357]
K15588 NSD1; [histone H3]-lysine36 N-dimethyltransferase NSD1 [EC:2.1.1.357]
K11424 WHSC1; [histone H3]-lysine36 N-dimethyltransferase NSD2 [EC:2.1.1.357]
K11425 WHSC1L1; [histone H3]-lysine4 N-dimethyltransferase / [histone H3]-lysine27 N-dimethyltransferase [EC:2.1.1.370 2.1.1.371]
K11432 PRDM2; [histone H3]-lysine9 N-trimethyltransferase PRDM2 [EC:2.1.1.355]
K11432 PRDM2; [histone H3]-lysine9 N-trimethyltransferase PRDM2 [EC:2.1.1.355]
K04462 MECOM; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
K20795 PRDM6; [histone H4]-lysine20 N-methyltransferase PRDM6 [EC:2.1.1.361]
K20796 PRDM7_9; [histone H3]-lysine4 N-trimethyltransferase PRDM7/9 [EC:2.1.1.354]
K20797 PRDM8; PR domain zinc finger protein 8 [EC:2.1.1.-]
K20797 PRDM8; PR domain zinc finger protein 8 [EC:2.1.1.-]
K20797 PRDM8; PR domain zinc finger protein 8 [EC:2.1.1.-]
K20797 PRDM8; PR domain zinc finger protein 8 [EC:2.1.1.-]
K24255 PRDM12; PR domain zinc finger protein 12 [EC:2.1.1.-]
K24255 PRDM12; PR domain zinc finger protein 12 [EC:2.1.1.-]
K22410 PRDM16; [histone H3]-lysine9 N-methyltransferase [EC:2.1.1.367]
K11422 SETD1; [histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:2.1.1.354]
K11422 SETD1; [histone H3]-lysine4 N-trimethyltransferase SETD1 [EC:2.1.1.354]
K11423 SETD2; [histone H3]-lysine36 N-trimethyltransferase [EC:2.1.1.359]
K27277 SETD4; SET domain-containing protein 4 [EC:2.1.1.- 2.1.1.364]
K05302 SETD6; N-lysine methyltransferase SETD6 [EC:2.1.1.-]
K11431 SETD7; [histone H3]-lysine4 N-methyltransferase [EC:2.1.1.364]
K11428 SETD8; [histone H4]-lysine20 N-methyltransferase SETD8 [EC:2.1.1.361]
K11428 SETD8; [histone H4]-lysine20 N-methyltransferase SETD8 [EC:2.1.1.361]
K11421 SETDB1; [histone H3]-N6,N6-dimethyl-lysine9 N-methyltransferase [EC:2.1.1.366]
K18494 SETDB2; [histone H3]-lysine9 N-trimethyltransferase SETDB2 [EC:2.1.1.355]
K11433 SETMAR; [histone H3]-lysine36 N-dimethyltransferase SETMAR [EC:2.1.1.357]
K11426 SMYD; [histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:2.1.1.354 2.1.1.357]
K11426 SMYD; [histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:2.1.1.354 2.1.1.357]
K11426 SMYD; [histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:2.1.1.354 2.1.1.357]
K11426 SMYD; [histone H3]-lysine4/36 N-trimethyltransferase SMYD [EC:2.1.1.354 2.1.1.357]
K11419 SUV39H; [histone H3]-lysine9 N-trimethyltransferase SUV39H [EC:2.1.1.355]
K11429 SUV420H; [histone H4]-N-methyl-L-lysine20 N-methyltransferase [EC:2.1.1.362]
K11429 SUV420H; [histone H4]-N-methyl-L-lysine20 N-methyltransferase [EC:2.1.1.362]
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PRMTs (protein arginine metyltransferases)
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HMT complexes
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Histone demethylases
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Polycomb repressive complex (PRC) and associated proteins
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Sir proteins
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Other histone modification proteins
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Chromosome condensation proteins
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Centromeric chromatin formation proteins
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Heterochromatin formation proteins
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Gene silencing
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Centrosome formation proteins
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Sister chromatid separation proteins
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Chromatin remodeling factors
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Prokaryotic type
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