KEGG Orthology (KO) - Homo sapiens (human)

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     KO
 09100 Metabolism
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
 09140 Cellular Processes
 
 09150 Organismal Systems
 
   09151 Immune system
     04640 Hematopoietic cell lineage [PATH:hsa04640]
     04610 Complement and coagulation cascades [PATH:hsa04610]
     04611 Platelet activation [PATH:hsa04611]
     04613 Neutrophil extracellular trap formation [PATH:hsa04613]
     04620 Toll-like receptor signaling pathway [PATH:hsa04620]
     04624 Toll and Imd signaling pathway
     04621 NOD-like receptor signaling pathway [PATH:hsa04621]
     04622 RIG-I-like receptor signaling pathway [PATH:hsa04622]
     04623 Cytosolic DNA-sensing pathway [PATH:hsa04623]
     04625 C-type lectin receptor signaling pathway [PATH:hsa04625]
     04650 Natural killer cell mediated cytotoxicity [PATH:hsa04650]
       3105 HLA-A; major histocompatibility complex, class I, A
       3106 HLA-B; major histocompatibility complex, class I, B
       3107 HLA-C; major histocompatibility complex, class I, C
       3134 HLA-F; major histocompatibility complex, class I, F
       3135 HLA-G; major histocompatibility complex, class I, G
       3133 HLA-E; major histocompatibility complex, class I, E
       3812 KIR3DL2; killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2
       3811 KIR3DL1; killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1
       115653 KIR3DL3; killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3
       3803 KIR2DL2; killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 2
       3802 KIR2DL1; killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1
       3804 KIR2DL3; killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3
       57292 KIR2DL5A; killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 5A
       3821 KLRC1; killer cell lectin like receptor C1
       3824 KLRD1; killer cell lectin like receptor D1
       5777 PTPN6; protein tyrosine phosphatase non-receptor type 6
       5781 PTPN11; protein tyrosine phosphatase non-receptor type 11
       3383 ICAM1; intercellular adhesion molecule 1
       3384 ICAM2; intercellular adhesion molecule 2
       3683 ITGAL; integrin subunit alpha L
       3689 ITGB2; integrin subunit beta 2
       2185 PTK2B; protein tyrosine kinase 2 beta
       10451 VAV3; vav guanine nucleotide exchange factor 3
       7409 VAV1; vav guanine nucleotide exchange factor 1
       7410 VAV2; vav guanine nucleotide exchange factor 2
       5879 RAC1; Rac family small GTPase 1
       5880 RAC2; Rac family small GTPase 2
       5881 RAC3; Rac family small GTPase 3
       5058 PAK1; p21 (RAC1) activated kinase 1
       5604 MAP2K1; mitogen-activated protein kinase kinase 1
       5605 MAP2K2; mitogen-activated protein kinase kinase 2
       5594 MAPK1; mitogen-activated protein kinase 1
       5595 MAPK3; mitogen-activated protein kinase 3
       7124 TNF; tumor necrosis factor
       1437 CSF2; colony stimulating factor 2
       3458 IFNG; interferon gamma
       3806 KIR2DS1; killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 1
       3808 KIR2DS3; killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 3
       3809 KIR2DS4; killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 4
       3810 KIR2DS5; killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 5
       100132285 KIR2DS2; killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 2
       3822 KLRC2; killer cell lectin like receptor C2
       3823 KLRC3; killer cell lectin like receptor C3
       9436 NCR2; natural cytotoxicity triggering receptor 2
       7305 TYROBP; transmembrane immune signaling adaptor TYROBP
       3932 LCK; LCK proto-oncogene, Src family tyrosine kinase
       102723407 IGH; immunoglobulin heavy variable 4-38-2-like
       2214 FCGR3A; Fc gamma receptor IIIa
       2215 FCGR3B; Fc gamma receptor IIIb
       9437 NCR1; natural cytotoxicity triggering receptor 1
       259197 NCR3; natural cytotoxicity triggering receptor 3
       2207 FCER1G; Fc epsilon receptor Ig
       919 CD247; CD247 molecule
       7535 ZAP70; zeta chain of T cell receptor associated protein kinase 70
       6850 SYK; spleen associated tyrosine kinase
       3937 LCP2; lymphocyte cytosolic protein 2
       27040 LAT; linker for activation of T cells
       7462 LAT2; linker for activation of T cells family member 2
       5335 PLCG1; phospholipase C gamma 1
       5336 PLCG2; phospholipase C gamma 2
       6452 SH3BP2; SH3 domain binding protein 2
       5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
       5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
       8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
       2534 FYN; FYN proto-oncogene, Src family tyrosine kinase
       6464 SHC1; SHC adaptor protein 1
       25759 SHC2; SHC adaptor protein 2
       53358 SHC3; SHC adaptor protein 3
       399694 SHC4; SHC adaptor protein 4
       2885 GRB2; growth factor receptor bound protein 2
       6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
       6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
       3265 HRAS; HRas proto-oncogene, GTPase
       3845 KRAS; KRAS proto-oncogene, GTPase
       4893 NRAS; NRAS proto-oncogene, GTPase
       369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
       673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
       5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
       4277 MICB; MHC class I polypeptide-related sequence B
       100507436 MICA; MHC class I polypeptide-related sequence A
       80329 ULBP1; UL16 binding protein 1
       80328 ULBP2; UL16 binding protein 2
       79465 ULBP3; UL16 binding protein 3
       22914 KLRK1; killer cell lectin like receptor K1
       100528032 KLRC4-KLRK1; KLRC4-KLRK1 readthrough
       10870 HCST; hematopoietic cell signal transducer
       962 CD48; CD48 molecule
       51744 CD244; CD244 molecule
       5530 PPP3CA; protein phosphatase 3 catalytic subunit alpha
       5532 PPP3CB; protein phosphatase 3 catalytic subunit beta
       5533 PPP3CC; protein phosphatase 3 catalytic subunit gamma
       5534 PPP3R1; protein phosphatase 3 regulatory subunit B, alpha
       5535 PPP3R2; protein phosphatase 3 regulatory subunit B, beta
       4772 NFATC1; nuclear factor of activated T cells 1
       4773 NFATC2; nuclear factor of activated T cells 2
       5578 PRKCA; protein kinase C alpha
       5579 PRKCB; protein kinase C beta
       5582 PRKCG; protein kinase C gamma
       117157 SH2D1B; SH2 domain containing 1B
       4068 SH2D1A; SH2 domain containing 1A
       3459 IFNGR1; interferon gamma receptor 1
       3460 IFNGR2; interferon gamma receptor 2
       3439 IFNA1; interferon alpha 1
       3440 IFNA2; interferon alpha 2
       3441 IFNA4; interferon alpha 4
       3442 IFNA5; interferon alpha 5
       3443 IFNA6; interferon alpha 6
       3444 IFNA7; interferon alpha 7
       3445 IFNA8; interferon alpha 8
       3446 IFNA10; interferon alpha 10
       3447 IFNA13; interferon alpha 13
       3448 IFNA14; interferon alpha 14
       3449 IFNA16; interferon alpha 16
       3451 IFNA17; interferon alpha 17
       3452 IFNA21; interferon alpha 21
       3456 IFNB1; interferon beta 1
       3454 IFNAR1; interferon alpha and beta receptor subunit 1
       3455 IFNAR2; interferon alpha and beta receptor subunit 2
       8743 TNFSF10; TNF superfamily member 10
       8797 TNFRSF10A; TNF receptor superfamily member 10a
       8795 TNFRSF10B; TNF receptor superfamily member 10b
       356 FASLG; Fas ligand
       355 FAS; Fas cell surface death receptor
       3002 GZMB; granzyme B
       5551 PRF1; perforin 1
       836 CASP3; caspase 3
       637 BID; BH3 interacting domain death agonist
       353091 RAET1G; retinoic acid early transcript 1G
       154064 RAET1L; retinoic acid early transcript 1L
       135250 RAET1E; retinoic acid early transcript 1E
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K07980 KIR3DL; killer cell immunoglobulin-like receptor 3DL
K07980 KIR3DL; killer cell immunoglobulin-like receptor 3DL
K07980 KIR3DL; killer cell immunoglobulin-like receptor 3DL
K07981 KIR2DL1_2_3; killer cell immunoglobulin-like receptor 2DL1/2/3
K07981 KIR2DL1_2_3; killer cell immunoglobulin-like receptor 2DL1/2/3
K07981 KIR2DL1_2_3; killer cell immunoglobulin-like receptor 2DL1/2/3
K24232 KIR2DL5; killer cell immunoglobulin-like receptor 2DL5
K06541 KLRC1; killer cell lectin-like receptor subfamily C1
K06516 KLRD1; killer cell lectin-like receptor subfamily D member 1
K05697 PTPN6; tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
K07293 PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K06490 ICAM1; intercellular adhesion molecule 1
K06523 ICAM2; intercellular adhesion molecule 2
K05718 ITGAL; integrin alpha L
K06464 ITGB2; integrin beta 2
K05871 PTK2B; focal adhesion kinase 2 [EC:2.7.10.2]
K05730 VAV; guanine nucleotide exchange factor VAV
K05730 VAV; guanine nucleotide exchange factor VAV
K05730 VAV; guanine nucleotide exchange factor VAV
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K03156 TNF; tumor necrosis factor superfamily, member 2
K05427 CSF2; granulocyte-macrophage colony-stimulating factor
K04687 IFNG; interferon gamma
K07982 KIR2DS; killer cell immunoglobulin-like receptor 2DS
K07982 KIR2DS; killer cell immunoglobulin-like receptor 2DS
K07982 KIR2DS; killer cell immunoglobulin-like receptor 2DS
K07982 KIR2DS; killer cell immunoglobulin-like receptor 2DS
K07982 KIR2DS; killer cell immunoglobulin-like receptor 2DS
K24233 KLRC2_3; killer cell lectin-like receptor subfamily C2/3
K24233 KLRC2_3; killer cell lectin-like receptor subfamily C2/3
K06742 NCR2; natural cytotoxicity triggering receptor 2
K07992 TYROBP; TYRO protein tyrosine kinase binding protein
K05856 LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
K06856 IGH; immunoglobulin heavy chain
K06463 FCGR3; low affinity immunoglobulin gamma Fc receptor III
K06463 FCGR3; low affinity immunoglobulin gamma Fc receptor III
K06741 NCR1; natural cytotoxicity triggering receptor 1
K06743 NCR3; natural cytotoxicity triggering receptor 3
K07983 FCER1G; high affinity immunoglobulin epsilon receptor subunit gamma
K06453 CD3Z; CD3Z antigen, zeta polypeptide
K07360 ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K07361 LCP2; lymphocyte cytosolic protein 2
K07362 LAT; linker for activation of T cells family member 1
K26356 LAT2; linker for activation of T-cells family member 2
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K07984 SH3BP2; SH3-domain binding protein 2
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K07985 MIC; MHC class I-related protein
K07985 MIC; MHC class I-related protein
K07986 ULBP; UL16 binding protein
K07986 ULBP; UL16 binding protein
K07986 ULBP; UL16 binding protein
K06728 KLRK1; killer cell lectin-like receptor subfamily K member 1
K06728 KLRK1; killer cell lectin-like receptor subfamily K member 1
K07988 HCST; hematopoietic cell signal transducer
K06479 CD48; CD48 antigen
K06582 CD244; natural killer cell receptor 2B4
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K07989 SH2D1B; SH2 domain-containing protein 1B
K07990 SH2D1A; SH2 domain-containing protein 1A
K05132 IFNGR1; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K04721 TNFSF10; tumor necrosis factor ligand superfamily member 10
K04722 TNFRSF10A_B; tumor necrosis factor receptor superfamily member 10A/B
K04722 TNFRSF10A_B; tumor necrosis factor receptor superfamily member 10A/B
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K01353 GZMB; granzyme B [EC:3.4.21.79]
K07818 PRF1; perforin 1
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04726 BID; BH3 interacting domain death agonist
K07987 RAET1; retinoic acid early transcript 1
K07987 RAET1; retinoic acid early transcript 1
K07987 RAET1; retinoic acid early transcript 1
     04612 Antigen processing and presentation [PATH:hsa04612]
     04660 T cell receptor signaling pathway [PATH:hsa04660]
     04658 Th1 and Th2 cell differentiation [PATH:hsa04658]
     04659 Th17 cell differentiation [PATH:hsa04659]
     04657 IL-17 signaling pathway [PATH:hsa04657]
     04662 B cell receptor signaling pathway [PATH:hsa04662]
     04664 Fc epsilon RI signaling pathway [PATH:hsa04664]
     04666 Fc gamma R-mediated phagocytosis [PATH:hsa04666]
     04670 Leukocyte transendothelial migration [PATH:hsa04670]
     04672 Intestinal immune network for IgA production [PATH:hsa04672]
     04062 Chemokine signaling pathway [PATH:hsa04062]
 
   09152 Endocrine system
 
   09153 Circulatory system
 
   09154 Digestive system
 
   09155 Excretory system
 
   09156 Nervous system
 
   09157 Sensory system
 
   09158 Development and regeneration
 
   09149 Aging
 
   09159 Environmental adaptation
 
 09160 Human Diseases
 
   09161 Cancer: overview
 
   09162 Cancer: specific types
 
   09172 Infectious disease: viral
     05166 Human T-cell leukemia virus 1 infection [PATH:hsa05166]
     05170 Human immunodeficiency virus 1 infection [PATH:hsa05170]
     05161 Hepatitis B [PATH:hsa05161]
     05160 Hepatitis C [PATH:hsa05160]
     05171 Coronavirus disease - COVID-19 [PATH:hsa05171]
     05164 Influenza A [PATH:hsa05164]
     05162 Measles [PATH:hsa05162]
     05168 Herpes simplex virus 1 infection [PATH:hsa05168]
     05163 Human cytomegalovirus infection [PATH:hsa05163]
     05167 Kaposi sarcoma-associated herpesvirus infection [PATH:hsa05167]
       718 C3; complement C3
       7098 TLR3; toll like receptor 3
       148022 TICAM1; TIR domain containing adaptor molecule 1
       7187 TRAF3; TNF receptor associated factor 3
       9641 IKBKE; inhibitor of nuclear factor kappa B kinase subunit epsilon
       29110 TBK1; TANK binding kinase 1
       3665 IRF7; interferon regulatory factor 7
       3439 IFNA1; interferon alpha 1
       3440 IFNA2; interferon alpha 2
       3441 IFNA4; interferon alpha 4
       3442 IFNA5; interferon alpha 5
       3443 IFNA6; interferon alpha 6
       3444 IFNA7; interferon alpha 7
       3445 IFNA8; interferon alpha 8
       3446 IFNA10; interferon alpha 10
       3447 IFNA13; interferon alpha 13
       3448 IFNA14; interferon alpha 14
       3449 IFNA16; interferon alpha 16
       3451 IFNA17; interferon alpha 17
       3452 IFNA21; interferon alpha 21
       3661 IRF3; interferon regulatory factor 3
       1387 CREBBP; CREB binding protein
       2033 EP300; E1A binding protein p300
       3456 IFNB1; interferon beta 1
       3454 IFNAR1; interferon alpha and beta receptor subunit 1
       3455 IFNAR2; interferon alpha and beta receptor subunit 2
       3716 JAK1; Janus kinase 1
       7297 TYK2; tyrosine kinase 2
       6772 STAT1; signal transducer and activator of transcription 1
       6773 STAT2; signal transducer and activator of transcription 2
       10379 IRF9; interferon regulatory factor 9
       5610 EIF2AK2; eukaryotic translation initiation factor 2 alpha kinase 2
       5600 MAPK11; mitogen-activated protein kinase 11
       6300 MAPK12; mitogen-activated protein kinase 12
       5603 MAPK13; mitogen-activated protein kinase 13
       1432 MAPK14; mitogen-activated protein kinase 14
       9261 MAPKAPK2; MAPK activated protein kinase 2
       5608 MAP2K6; mitogen-activated protein kinase kinase 6
       7538 ZFP36; ZFP36 ring finger protein
       3569 IL6; interleukin 6
       1437 CSF2; colony stimulating factor 2
       1232 CCR3; C-C motif chemokine receptor 3
       1234 CCR5; C-C motif chemokine receptor 5
       1230 CCR1; C-C motif chemokine receptor 1
       1233 CCR4; C-C motif chemokine receptor 4
       1237 CCR8; C-C motif chemokine receptor 8
       355 FAS; Fas cell surface death receptor
       8772 FADD; Fas associated via death domain
       841 CASP8; caspase 8
       637 BID; BH3 interacting domain death agonist
       581 BAX; BCL2 associated X, apoptosis regulator
       578 BAK1; BCL2 antagonist/killer 1
       54205 CYCS; cytochrome c, somatic
       842 CASP9; caspase 9
       836 CASP3; caspase 3
       7132 TNFRSF1A; TNF receptor superfamily member 1A
       8717 TRADD; TNFRSF1A associated via death domain
       7186 TRAF2; TNF receptor associated factor 2
       1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
       3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
       8517 IKBKG; inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
       4792 NFKBIA; NFKB inhibitor alpha
       4790 NFKB1; nuclear factor kappa B subunit 1
       5970 RELA; RELA proto-oncogene, NF-kB subunit
       7157 TP53; tumor protein p53
       1026 CDKN1A; cyclin dependent kinase inhibitor 1A
       1019 CDK4; cyclin dependent kinase 4
       1021 CDK6; cyclin dependent kinase 6
       5925 RB1; RB transcriptional corepressor 1
       1869 E2F1; E2F transcription factor 1
       1870 E2F2; E2F transcription factor 2
       1871 E2F3; E2F transcription factor 3
       3105 HLA-A; major histocompatibility complex, class I, A
       3106 HLA-B; major histocompatibility complex, class I, B
       3107 HLA-C; major histocompatibility complex, class I, C
       3134 HLA-F; major histocompatibility complex, class I, F
       3135 HLA-G; major histocompatibility complex, class I, G
       3133 HLA-E; major histocompatibility complex, class I, E
       3459 IFNGR1; interferon gamma receptor 1
       3383 ICAM1; intercellular adhesion molecule 1
       942 CD86; CD86 molecule
       4277 MICB; MHC class I polypeptide-related sequence B
       100507436 MICA; MHC class I polypeptide-related sequence A
       9976 CLEC2B; C-type lectin domain family 2 member B
       7311 UBA52; ubiquitin A-52 residue ribosomal protein fusion product 1
       6233 RPS27A; ribosomal protein S27a
       7314 UBB; ubiquitin B
       7316 UBC; ubiquitin C
       8678 BECN1; beclin 1
       441925 BECN2; beclin 2
       22863 ATG14; autophagy related 14
       5289 PIK3C3; phosphatidylinositol 3-kinase catalytic subunit type 3
       64422 ATG3; autophagy related 3
       440738 MAP1LC3C; microtubule associated protein 1 light chain 3 gamma
       81631 MAP1LC3B; microtubule associated protein 1 light chain 3 beta
       84557 MAP1LC3A; microtubule associated protein 1 light chain 3 alpha
       643246 MAP1LC3B2; microtubule associated protein 1 light chain 3 beta 2
       2782 GNB1; G protein subunit beta 1
       2783 GNB2; G protein subunit beta 2
       2784 GNB3; G protein subunit beta 3
       59345 GNB4; G protein subunit beta 4
       10681 GNB5; G protein subunit beta 5
       54331 GNG2; G protein subunit gamma 2
       2785 GNG3; G protein subunit gamma 3
       2786 GNG4; G protein subunit gamma 4
       2787 GNG5; G protein subunit gamma 5
       2788 GNG7; G protein subunit gamma 7
       94235 GNG8; G protein subunit gamma 8
       2790 GNG10; G protein subunit gamma 10
       2791 GNG11; G protein subunit gamma 11
       55970 GNG12; G protein subunit gamma 12
       51764 GNG13; G protein subunit gamma 13
       2792 GNGT1; G protein subunit gamma transducin 1
       2793 GNGT2; G protein subunit gamma transducin 2
       3265 HRAS; HRas proto-oncogene, GTPase
       3845 KRAS; KRAS proto-oncogene, GTPase
       4893 NRAS; NRAS proto-oncogene, GTPase
       5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
       5604 MAP2K1; mitogen-activated protein kinase kinase 1
       5605 MAP2K2; mitogen-activated protein kinase kinase 2
       5594 MAPK1; mitogen-activated protein kinase 1
       5595 MAPK3; mitogen-activated protein kinase 3
       3091 HIF1A; hypoxia inducible factor 1 subunit alpha
       3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
       2353 FOS; Fos proto-oncogene, AP-1 transcription factor subunit
       5294 PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
       23533 PIK3R5; phosphoinositide-3-kinase regulatory subunit 5
       146850 PIK3R6; phosphoinositide-3-kinase regulatory subunit 6
       5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
       5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
       8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
       207 AKT1; AKT serine/threonine kinase 1
       208 AKT2; AKT serine/threonine kinase 2
       10000 AKT3; AKT serine/threonine kinase 3
       2475 MTOR; mechanistic target of rapamycin kinase
       57580 PREX1; phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1
       5879 RAC1; Rac family small GTPase 1
       5599 MAPK8; mitogen-activated protein kinase 8
       5602 MAPK10; mitogen-activated protein kinase 10
       5601 MAPK9; mitogen-activated protein kinase 9
       344807 CD200R1L; CD200 receptor 1 like
       131450 CD200R1; CD200 receptor 1
       6850 SYK; spleen associated tyrosine kinase
       6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase
       3055 HCK; HCK proto-oncogene, Src family tyrosine kinase
       4067 LYN; LYN proto-oncogene, Src family tyrosine kinase
       6416 MAP2K4; mitogen-activated protein kinase kinase 4
       5609 MAP2K7; mitogen-activated protein kinase kinase 7
       5336 PLCG2; phospholipase C gamma 2
       5335 PLCG1; phospholipase C gamma 1
       3708 ITPR1; inositol 1,4,5-trisphosphate receptor type 1
       3709 ITPR2; inositol 1,4,5-trisphosphate receptor type 2
       3710 ITPR3; inositol 1,4,5-trisphosphate receptor type 3
       810 CALML3; calmodulin like 3
       805 CALM2; calmodulin 2
       808 CALM3; calmodulin 3
       801 CALM1; calmodulin 1
       163688 CALML6; calmodulin like 6
       51806 CALML5; calmodulin like 5
       91860 CALML4; calmodulin like 4
       5530 PPP3CA; protein phosphatase 3 catalytic subunit alpha
       5532 PPP3CB; protein phosphatase 3 catalytic subunit beta
       5533 PPP3CC; protein phosphatase 3 catalytic subunit gamma
       5534 PPP3R1; protein phosphatase 3 regulatory subunit B, alpha
       5535 PPP3R2; protein phosphatase 3 regulatory subunit B, beta
       4772 NFATC1; nuclear factor of activated T cells 1
       4773 NFATC2; nuclear factor of activated T cells 2
       4775 NFATC3; nuclear factor of activated T cells 3
       4776 NFATC4; nuclear factor of activated T cells 4
       3576 CXCL8; C-X-C motif chemokine ligand 8
       5743 PTGS2; prostaglandin-endoperoxide synthase 2
       2919 CXCL1; C-X-C motif chemokine ligand 1
       2920 CXCL2; C-X-C motif chemokine ligand 2
       2921 CXCL3; C-X-C motif chemokine ligand 3
       1827 RCAN1; regulator of calcineurin 1
       2247 FGF2; fibroblast growth factor 2
       7422 VEGFA; vascular endothelial growth factor A
       5155 PDGFB; platelet derived growth factor subunit B
       285 ANGPT2; angiopoietin 2
       3572 IL6ST; interleukin 6 cytokine family signal transducer
       3717 JAK2; Janus kinase 2
       6774 STAT3; signal transducer and activator of transcription 3
       2932 GSK3B; glycogen synthase kinase 3 beta
       1499 CTNNB1; catenin beta 1
       6932 TCF7; transcription factor 7
       83439 TCF7L1; transcription factor 7 like 1
       6934 TCF7L2; transcription factor 7 like 2
       51176 LEF1; lymphoid enhancer binding factor 1
       1385 CREB1; cAMP responsive element binding protein 1
       595 CCND1; cyclin D1
       4609 MYC; MYC proto-oncogene, bHLH transcription factor
K03990 C3; complement component 3
K05401 TLR3; toll-like receptor 3
K05842 TRIF; toll-like receptor adapter molecule 1
K03174 TRAF3; TNF receptor-associated factor 3
K07211 IKBKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K09447 IRF7; interferon regulatory factor 7
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05411 IRF3; interferon regulatory factor 3
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K05415 IFNB; interferon beta
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K04693 IRF9; interferon regulatory factor 9
K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
K04433 MAP2K6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K15308 TTP; tristetraprolin
K05405 IL6; interleukin 6
K05427 CSF2; granulocyte-macrophage colony-stimulating factor
K04178 CCR3; C-C chemokine receptor type 3
K04180 CCR5; C-C chemokine receptor type 5
K04176 CCR1; C-C chemokine receptor type 1
K04179 CCR4; C-C chemokine receptor type 4
K04183 CCR8; C-C chemokine receptor type 8
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K08738 CYC; cytochrome c
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K03158 TNFRSF1A; tumor necrosis factor receptor superfamily member 1A
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K06751 MHC1; MHC class I antigen
K05132 IFNGR1; interferon gamma receptor 1
K06490 ICAM1; intercellular adhesion molecule 1
K05413 CD86; CD86 antigen
K07985 MIC; MHC class I-related protein
K07985 MIC; MHC class I-related protein
K10071 CLEC2B; C-type lectin domain family 2 member B
K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
K04551 UBB; ubiquitin B
K08770 UBC; ubiquitin C
K08334 BECN; beclin
K08334 BECN; beclin
K17889 ATG14L; beclin 1-associated autophagy-related key regulator
K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
K10435 MAP1LC; microtubule-associated protein 1 light chain
K10435 MAP1LC; microtubule-associated protein 1 light chain
K10435 MAP1LC; microtubule-associated protein 1 light chain
K10435 MAP1LC; microtubule-associated protein 1 light chain
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K21289 PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153]
K21290 PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6
K21290 PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K12365 PREX1; phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchanger 1 protein
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K21668 CD200R; cell surface glycoprotein CD200 receptor
K21668 CD200R; cell surface glycoprotein CD200 receptor
K05855 SYK; spleen tyrosine kinase [EC:2.7.10.2]
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K08893 HCK; hemopoietic cell kinase [EC:2.7.10.2]
K05854 LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]
K04430 MAP2K4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K04446 NFATC1; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4; nuclear factor of activated T-cells, cytoplasmic 4
K10030 IL8; interleukin 8
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K05505 CXCL1_2_3; C-X-C motif chemokine 1/2/3
K05505 CXCL1_2_3; C-X-C motif chemokine 1/2/3
K05505 CXCL1_2_3; C-X-C motif chemokine 1/2/3
K17901 RCAN1; calcipressin-1
K18497 FGF2; fibroblast growth factor 2
K05448 VEGFA; vascular endothelial growth factor A
K17386 PDGFB; platelet-derived growth factor subunit B
K05466 ANGPT2; angiopoietin 2
K05060 IL6ST; interleukin 6 signal transducer
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02105 CTNNB1; catenin beta 1
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04503 CCND1; G1/S-specific cyclin-D1
K04377 MYC; Myc proto-oncogene protein
     05169 Epstein-Barr virus infection [PATH:hsa05169]
     05165 Human papillomavirus infection [PATH:hsa05165]
 
   09171 Infectious disease: bacterial
 
   09174 Infectious disease: parasitic
 
   09163 Immune disease
 
   09164 Neurodegenerative disease
 
   09165 Substance dependence
 
   09166 Cardiovascular disease
 
   09167 Endocrine and metabolic disease
 
   09175 Drug resistance: antimicrobial
 
   09176 Drug resistance: antineoplastic
 
 09180 Brite Hierarchies
 
 09190 Not Included in Pathway or Brite

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: April 24, 2024