KEGG Orthology (KO) - Homo sapiens (human)

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     KO
 09100 Metabolism
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
   09131 Membrane transport
 
   09132 Signal transduction
     02020 Two-component system
     04010 MAPK signaling pathway [PATH:hsa04010]
     04013 MAPK signaling pathway - fly
     04016 MAPK signaling pathway - plant
     04011 MAPK signaling pathway - yeast
     04012 ErbB signaling pathway [PATH:hsa04012]
     04014 Ras signaling pathway [PATH:hsa04014]
     04015 Rap1 signaling pathway [PATH:hsa04015]
     04310 Wnt signaling pathway [PATH:hsa04310]
     04330 Notch signaling pathway [PATH:hsa04330]
     04340 Hedgehog signaling pathway [PATH:hsa04340]
     04341 Hedgehog signaling pathway - fly
     04350 TGF-beta signaling pathway [PATH:hsa04350]
     04390 Hippo signaling pathway [PATH:hsa04390]
     04391 Hippo signaling pathway - fly
     04392 Hippo signaling pathway - multiple species [PATH:hsa04392]
     04370 VEGF signaling pathway [PATH:hsa04370]
     04371 Apelin signaling pathway [PATH:hsa04371]
     04630 JAK-STAT signaling pathway [PATH:hsa04630]
     04064 NF-kappa B signaling pathway [PATH:hsa04064]
     04668 TNF signaling pathway [PATH:hsa04668]
     04066 HIF-1 signaling pathway [PATH:hsa04066]
       3569 IL6; interleukin 6
       3570 IL6R; interleukin 6 receptor
       6774 STAT3; signal transducer and activator of transcription 3
       7099 TLR4; toll like receptor 4
       3458 IFNG; interferon gamma
       3459 IFNGR1; interferon gamma receptor 1
       3460 IFNGR2; interferon gamma receptor 2
       5970 RELA; RELA proto-oncogene, NF-kB subunit
       4790 NFKB1; nuclear factor kappa B subunit 1
       3630 INS; insulin
       1950 EGF; epidermal growth factor
       3479 IGF1; insulin like growth factor 1
       3643 INSR; insulin receptor
       1956 EGFR; epidermal growth factor receptor
       3480 IGF1R; insulin like growth factor 1 receptor
       2064 ERBB2; erb-b2 receptor tyrosine kinase 2
       5604 MAP2K1; mitogen-activated protein kinase kinase 1
       5605 MAP2K2; mitogen-activated protein kinase kinase 2
       5594 MAPK1; mitogen-activated protein kinase 1
       5595 MAPK3; mitogen-activated protein kinase 3
       8569 MKNK1; MAPK interacting serine/threonine kinase 1
       2872 MKNK2; MAPK interacting serine/threonine kinase 2
       5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
       5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
       8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
       207 AKT1; AKT serine/threonine kinase 1
       208 AKT2; AKT serine/threonine kinase 2
       10000 AKT3; AKT serine/threonine kinase 3
       2475 MTOR; mechanistic target of rapamycin kinase
       1978 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
       1977 EIF4E; eukaryotic translation initiation factor 4E
       9470 EIF4E2; eukaryotic translation initiation factor 4E family member 2
       253314 EIF4E1B; eukaryotic translation initiation factor 4E family member 1B
       6198 RPS6KB1; ribosomal protein S6 kinase B1
       6199 RPS6KB2; ribosomal protein S6 kinase B2
       6194 RPS6; ribosomal protein S6
       3091 HIF1A; hypoxia inducible factor 1 subunit alpha
       7428 VHL; von Hippel-Lindau tumor suppressor
       9978 RBX1; ring-box 1
       6921 ELOC; elongin C
       6923 ELOB; elongin B
       8453 CUL2; cullin 2
       54583 EGLN1; egl-9 family hypoxia inducible factor 1
       112399 EGLN3; egl-9 family hypoxia inducible factor 3
       112398 EGLN2; egl-9 family hypoxia inducible factor 2
       405 ARNT; aryl hydrocarbon receptor nuclear translocator
       1387 CREBBP; CREB binding protein
       2033 EP300; E1A binding protein p300
       1536 CYBB; cytochrome b-245 beta chain
       5335 PLCG1; phospholipase C gamma 1
       5336 PLCG2; phospholipase C gamma 2
       5578 PRKCA; protein kinase C alpha
       5579 PRKCB; protein kinase C beta
       5582 PRKCG; protein kinase C gamma
       815 CAMK2A; calcium/calmodulin dependent protein kinase II alpha
       817 CAMK2D; calcium/calmodulin dependent protein kinase II delta
       816 CAMK2B; calcium/calmodulin dependent protein kinase II beta
       818 CAMK2G; calcium/calmodulin dependent protein kinase II gamma
       7076 TIMP1; TIMP metallopeptidase inhibitor 1
       4055 LTBR; lymphotoxin beta receptor
       2056 EPO; erythropoietin
       7018 TF; transferrin
       7037 TFRC; transferrin receptor
       7422 VEGFA; vascular endothelial growth factor A
       2321 FLT1; fms related receptor tyrosine kinase 1
       5054 SERPINE1; serpin family E member 1
       284 ANGPT1; angiopoietin 1
       285 ANGPT2; angiopoietin 2
       51378 ANGPT4; angiopoietin 4
       7010 TEK; TEK receptor tyrosine kinase
       1906 EDN1; endothelin 1
       4843 NOS2; nitric oxide synthase 2
       4846 NOS3; nitric oxide synthase 3
       3162 HMOX1; heme oxygenase 1
       4878 NPPA; natriuretic peptide A
       6513 SLC2A1; solute carrier family 2 member 1
       5163 PDK1; pyruvate dehydrogenase kinase 1
       3101 HK3; hexokinase 3
       3098 HK1; hexokinase 1
       3099 HK2; hexokinase 2
       80201 HKDC1; hexokinase domain containing 1
       5213 PFKM; phosphofructokinase, muscle
       5214 PFKP; phosphofructokinase, platelet
       5211 PFKL; phosphofructokinase, liver type
       2597 GAPDH; glyceraldehyde-3-phosphate dehydrogenase
       230 ALDOC; aldolase, fructose-bisphosphate C
       226 ALDOA; aldolase, fructose-bisphosphate A
       229 ALDOB; aldolase, fructose-bisphosphate B
       2027 ENO3; enolase 3
       2026 ENO2; enolase 2
       2023 ENO1; enolase 1
       387712 ENO4; enolase 4
       5232 PGK2; phosphoglycerate kinase 2
       5230 PGK1; phosphoglycerate kinase 1
       5209 PFKFB3; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
       160287 LDHAL6A; lactate dehydrogenase A like 6A
       92483 LDHAL6B; lactate dehydrogenase A like 6B
       3939 LDHA; lactate dehydrogenase A
       3945 LDHB; lactate dehydrogenase B
       3948 LDHC; lactate dehydrogenase C
       596 BCL2; BCL2 apoptosis regulator
       1026 CDKN1A; cyclin dependent kinase inhibitor 1A
       1027 CDKN1B; cyclin dependent kinase inhibitor 1B
       5161 PDHA2; pyruvate dehydrogenase E1 subunit alpha 2
       5160 PDHA1; pyruvate dehydrogenase E1 subunit alpha 1
       5162 PDHB; pyruvate dehydrogenase E1 subunit beta
K05405 IL6; interleukin 6
K05055 IL6R; interleukin 6 receptor
K04692 STAT3; signal transducer and activator of transcription 3
K10160 TLR4; toll-like receptor 4
K04687 IFNG; interferon gamma
K05132 IFNGR1; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K04735 RELA; transcription factor p65
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04526 INS; insulin
K04357 EGF; epidermal growth factor
K05459 IGF1; insulin-like growth factor 1
K04527 INSR; insulin receptor [EC:2.7.10.1]
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04372 MKNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
K04372 MKNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K03259 EIF4E; translation initiation factor 4E
K03259 EIF4E; translation initiation factor 4E
K03259 EIF4E; translation initiation factor 4E
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02991 RP-S6e; small subunit ribosomal protein S6e
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K03871 VHL; von Hippel-Lindau disease tumor supressor
K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K03872 ELOC; elongin-C
K03873 ELOB; elongin-B
K03870 CUL2; cullin 2
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K21421 NOX2; NADPH oxidase 2 [EC:1.-.-.-]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K16451 TIMP1; metalloproteinase inhibitor 1
K03159 TNFRSF3; lymphotoxin beta receptor TNFR superfamily member 3
K05437 EPO; erythropoietin
K14736 TF; transferrin
K06503 TFRC; transferrin receptor
K05448 VEGFA; vascular endothelial growth factor A
K05096 FLT1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
K03982 SERPINE1; plasminogen activator inhibitor 1
K05465 ANGPT1; angiopoietin 1
K05466 ANGPT2; angiopoietin 2
K05467 ANGPT4; angiopoietin 4
K05121 TEK; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]
K16366 EDN1; endothelin-1
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K12334 NPPA; natriuretic peptide A
K07299 SLC2A1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K12077 PDK1; pyruvate dehydrogenase kinase isoform 1 [EC:2.7.11.2]
K00844 HK; hexokinase [EC:2.7.1.1]
K00844 HK; hexokinase [EC:2.7.1.1]
K00844 HK; hexokinase [EC:2.7.1.1]
K00844 HK; hexokinase [EC:2.7.1.1]
K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12]
K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
K01689 ENO; enolase [EC:4.2.1.11]
K01689 ENO; enolase [EC:4.2.1.11]
K01689 ENO; enolase [EC:4.2.1.11]
K01689 ENO; enolase [EC:4.2.1.11]
K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
K01103 PFKFB3; 6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 3 [EC:2.7.1.105 3.1.3.46]
K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
K02161 BCL2; apoptosis regulator Bcl-2
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K00161 PDHA; pyruvate dehydrogenase E1 component alpha subunit [EC:1.2.4.1]
K00161 PDHA; pyruvate dehydrogenase E1 component alpha subunit [EC:1.2.4.1]
K00162 PDHB; pyruvate dehydrogenase E1 component beta subunit [EC:1.2.4.1]
     04068 FoxO signaling pathway [PATH:hsa04068]
     04020 Calcium signaling pathway [PATH:hsa04020]
     04070 Phosphatidylinositol signaling system [PATH:hsa04070]
     04072 Phospholipase D signaling pathway [PATH:hsa04072]
     04071 Sphingolipid signaling pathway [PATH:hsa04071]
     04024 cAMP signaling pathway [PATH:hsa04024]
     04022 cGMP-PKG signaling pathway [PATH:hsa04022]
     04151 PI3K-Akt signaling pathway [PATH:hsa04151]
     04152 AMPK signaling pathway [PATH:hsa04152]
     04150 mTOR signaling pathway [PATH:hsa04150]
     04075 Plant hormone signal transduction
 
   09133 Signaling molecules and interaction
 
 09140 Cellular Processes
 
 09150 Organismal Systems
 
 09160 Human Diseases
 
   09161 Cancer: overview
     05200 Pathways in cancer [PATH:hsa05200]
       1630 DCC; DCC netrin 1 receptor
       836 CASP3; caspase 3
       842 CASP9; caspase 9
       26060 APPL1; adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
       999 CDH1; cadherin 1
       1499 CTNNB1; catenin beta 1
       29119 CTNNA3; catenin alpha 3
       1495 CTNNA1; catenin alpha 1
       1496 CTNNA2; catenin alpha 2
       8312 AXIN1; axin 1
       8313 AXIN2; axin 2
       324 APC; APC regulator of WNT signaling pathway
       10297 APC2; APC regulator of WNT signaling pathway 2
       2932 GSK3B; glycogen synthase kinase 3 beta
       6932 TCF7; transcription factor 7
       83439 TCF7L1; transcription factor 7 like 1
       6934 TCF7L2; transcription factor 7 like 2
       51176 LEF1; lymphoid enhancer binding factor 1
       332 BIRC5; baculoviral IAP repeat containing 5
       4609 MYC; MYC proto-oncogene, bHLH transcription factor
       595 CCND1; cyclin D1
       7471 WNT1; Wnt family member 1
       7472 WNT2; Wnt family member 2
       7482 WNT2B; Wnt family member 2B
       7473 WNT3; Wnt family member 3
       89780 WNT3A; Wnt family member 3A
       54361 WNT4; Wnt family member 4
       7474 WNT5A; Wnt family member 5A
       81029 WNT5B; Wnt family member 5B
       7475 WNT6; Wnt family member 6
       7476 WNT7A; Wnt family member 7A
       7477 WNT7B; Wnt family member 7B
       7478 WNT8A; Wnt family member 8A
       7479 WNT8B; Wnt family member 8B
       7483 WNT9A; Wnt family member 9A
       7484 WNT9B; Wnt family member 9B
       7480 WNT10B; Wnt family member 10B
       80326 WNT10A; Wnt family member 10A
       7481 WNT11; Wnt family member 11
       51384 WNT16; Wnt family member 16
       8321 FZD1; frizzled class receptor 1
       8324 FZD7; frizzled class receptor 7
       2535 FZD2; frizzled class receptor 2
       7976 FZD3; frizzled class receptor 3
       8322 FZD4; frizzled class receptor 4
       7855 FZD5; frizzled class receptor 5
       8325 FZD8; frizzled class receptor 8
       8323 FZD6; frizzled class receptor 6
       11211 FZD10; frizzled class receptor 10
       8326 FZD9; frizzled class receptor 9
       4041 LRP5; LDL receptor related protein 5
       4040 LRP6; LDL receptor related protein 6
       1857 DVL3; dishevelled segment polarity protein 3
       1856 DVL2; dishevelled segment polarity protein 2
       1855 DVL1; dishevelled segment polarity protein 1
       10023 FRAT1; FRAT regulator of WNT signaling pathway 1
       23401 FRAT2; FRAT regulator of WNT signaling pathway 2
       2147 F2; coagulation factor II, thrombin
       183 AGT; angiotensinogen
       2149 F2R; coagulation factor II thrombin receptor
       9002 F2RL3; F2R like thrombin or trypsin receptor 3
       1902 LPAR1; lysophosphatidic acid receptor 1
       9170 LPAR2; lysophosphatidic acid receptor 2
       23566 LPAR3; lysophosphatidic acid receptor 3
       2846 LPAR4; lysophosphatidic acid receptor 4
       57121 LPAR5; lysophosphatidic acid receptor 5
       10161 LPAR6; lysophosphatidic acid receptor 6
       185 AGTR1; angiotensin II receptor type 1
       2768 GNA12; G protein subunit alpha 12
       10672 GNA13; G protein subunit alpha 13
       23365 ARHGEF12; Rho guanine nucleotide exchange factor 12
       9826 ARHGEF11; Rho guanine nucleotide exchange factor 11
       9138 ARHGEF1; Rho guanine nucleotide exchange factor 1
       57449 PLEKHG5; pleckstrin homology and RhoGEF domain containing G5
       387 RHOA; ras homolog family member A
       6093 ROCK1; Rho associated coiled-coil containing protein kinase 1
       9475 ROCK2; Rho associated coiled-coil containing protein kinase 2
       6387 CXCL12; C-X-C motif chemokine ligand 12
       7852 CXCR4; C-X-C motif chemokine receptor 4
       2770 GNAI1; G protein subunit alpha i1
       2773 GNAI3; G protein subunit alpha i3
       2771 GNAI2; G protein subunit alpha i2
       5731 PTGER1; prostaglandin E receptor 1
       5732 PTGER2; prostaglandin E receptor 2
       5733 PTGER3; prostaglandin E receptor 3
       5734 PTGER4; prostaglandin E receptor 4
       2778 GNAS; GNAS complex locus
       107 ADCY1; adenylate cyclase 1
       108 ADCY2; adenylate cyclase 2
       109 ADCY3; adenylate cyclase 3
       196883 ADCY4; adenylate cyclase 4
       111 ADCY5; adenylate cyclase 5
       112 ADCY6; adenylate cyclase 6
       113 ADCY7; adenylate cyclase 7
       114 ADCY8; adenylate cyclase 8
       115 ADCY9; adenylate cyclase 9
       5566 PRKACA; protein kinase cAMP-activated catalytic subunit alpha
       5567 PRKACB; protein kinase cAMP-activated catalytic subunit beta
       5568 PRKACG; protein kinase cAMP-activated catalytic subunit gamma
       2782 GNB1; G protein subunit beta 1
       2783 GNB2; G protein subunit beta 2
       2784 GNB3; G protein subunit beta 3
       59345 GNB4; G protein subunit beta 4
       10681 GNB5; G protein subunit beta 5
       54331 GNG2; G protein subunit gamma 2
       2785 GNG3; G protein subunit gamma 3
       2786 GNG4; G protein subunit gamma 4
       2787 GNG5; G protein subunit gamma 5
       2788 GNG7; G protein subunit gamma 7
       94235 GNG8; G protein subunit gamma 8
       2790 GNG10; G protein subunit gamma 10
       2791 GNG11; G protein subunit gamma 11
       55970 GNG12; G protein subunit gamma 12
       51764 GNG13; G protein subunit gamma 13
       2792 GNGT1; G protein subunit gamma transducin 1
       2793 GNGT2; G protein subunit gamma transducin 2
       1284 COL4A2; collagen type IV alpha 2 chain
       1286 COL4A4; collagen type IV alpha 4 chain
       1288 COL4A6; collagen type IV alpha 6 chain
       1282 COL4A1; collagen type IV alpha 1 chain
       1287 COL4A5; collagen type IV alpha 5 chain
       1285 COL4A3; collagen type IV alpha 3 chain
       284217 LAMA1; laminin subunit alpha 1
       3908 LAMA2; laminin subunit alpha 2
       3909 LAMA3; laminin subunit alpha 3
       3911 LAMA5; laminin subunit alpha 5
       3910 LAMA4; laminin subunit alpha 4
       3912 LAMB1; laminin subunit beta 1
       3913 LAMB2; laminin subunit beta 2
       3914 LAMB3; laminin subunit beta 3
       22798 LAMB4; laminin subunit beta 4
       3915 LAMC1; laminin subunit gamma 1
       3918 LAMC2; laminin subunit gamma 2
       10319 LAMC3; laminin subunit gamma 3
       2335 FN1; fibronectin 1
       3673 ITGA2; integrin subunit alpha 2
       3674 ITGA2B; integrin subunit alpha 2b
       3675 ITGA3; integrin subunit alpha 3
       3655 ITGA6; integrin subunit alpha 6
       3685 ITGAV; integrin subunit alpha V
       3688 ITGB1; integrin subunit beta 1
       5747 PTK2; protein tyrosine kinase 2
       5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
       5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
       8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
       5728 PTEN; phosphatase and tensin homolog
       4824 NKX3-1; NK3 homeobox 1
       207 AKT1; AKT serine/threonine kinase 1
       208 AKT2; AKT serine/threonine kinase 2
       10000 AKT3; AKT serine/threonine kinase 3
       1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
       3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
       8517 IKBKG; inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
       4792 NFKBIA; NFKB inhibitor alpha
       4790 NFKB1; nuclear factor kappa B subunit 1
       4791 NFKB2; nuclear factor kappa B subunit 2
       5970 RELA; RELA proto-oncogene, NF-kB subunit
       5743 PTGS2; prostaglandin-endoperoxide synthase 2
       4843 NOS2; nitric oxide synthase 2
       596 BCL2; BCL2 apoptosis regulator
       329 BIRC2; baculoviral IAP repeat containing 2
       330 BIRC3; baculoviral IAP repeat containing 3
       331 XIAP; X-linked inhibitor of apoptosis
       79444 BIRC7; baculoviral IAP repeat containing 7
       598 BCL2L1; BCL2 like 1
       7185 TRAF1; TNF receptor associated factor 1
       7186 TRAF2; TNF receptor associated factor 2
       7187 TRAF3; TNF receptor associated factor 3
       9618 TRAF4; TNF receptor associated factor 4
       7188 TRAF5; TNF receptor associated factor 5
       7189 TRAF6; TNF receptor associated factor 6
       2475 MTOR; mechanistic target of rapamycin kinase
       6198 RPS6KB1; ribosomal protein S6 kinase B1
       6199 RPS6KB2; ribosomal protein S6 kinase B2
       572 BAD; BCL2 associated agonist of cell death
       2308 FOXO1; forkhead box O1
       4193 MDM2; MDM2 proto-oncogene
       7157 TP53; tumor protein p53
       1027 CDKN1B; cyclin dependent kinase inhibitor 1B
       1026 CDKN1A; cyclin dependent kinase inhibitor 1A
       613 BCR; BCR activator of RhoGEF and GTPase
       25 ABL1; ABL proto-oncogene 1, non-receptor tyrosine kinase
       1398 CRK; CRK proto-oncogene, adaptor protein
       1399 CRKL; CRK like proto-oncogene, adaptor protein
       867 CBL; Cbl proto-oncogene
       6776 STAT5A; signal transducer and activator of transcription 5A
       6777 STAT5B; signal transducer and activator of transcription 5B
       5292 PIM1; Pim-1 proto-oncogene, serine/threonine kinase
       11040 PIM2; Pim-2 proto-oncogene, serine/threonine kinase
       3827 KNG1; kininogen 1
       1906 EDN1; endothelin 1
       623 BDKRB1; bradykinin receptor B1
       624 BDKRB2; bradykinin receptor B2
       1909 EDNRA; endothelin receptor type A
       1910 EDNRB; endothelin receptor type B
       2776 GNAQ; G protein subunit alpha q
       2767 GNA11; G protein subunit alpha 11
       23236 PLCB1; phospholipase C beta 1
       5330 PLCB2; phospholipase C beta 2
       5331 PLCB3; phospholipase C beta 3
       5332 PLCB4; phospholipase C beta 4
       5578 PRKCA; protein kinase C alpha
       5579 PRKCB; protein kinase C beta
       5582 PRKCG; protein kinase C gamma
       3558 IL2; interleukin 2
       3562 IL3; interleukin 3
       3565 IL4; interleukin 4
       3567 IL5; interleukin 5
       3569 IL6; interleukin 6
       3574 IL7; interleukin 7
       3592 IL12A; interleukin 12A
       3593 IL12B; interleukin 12B
       3596 IL13; interleukin 13
       3600 IL15; interleukin 15
       51561 IL23A; interleukin 23 subunit alpha
       2056 EPO; erythropoietin
       3439 IFNA1; interferon alpha 1
       3440 IFNA2; interferon alpha 2
       3441 IFNA4; interferon alpha 4
       3442 IFNA5; interferon alpha 5
       3443 IFNA6; interferon alpha 6
       3444 IFNA7; interferon alpha 7
       3445 IFNA8; interferon alpha 8
       3446 IFNA10; interferon alpha 10
       3447 IFNA13; interferon alpha 13
       3448 IFNA14; interferon alpha 14
       3449 IFNA16; interferon alpha 16
       3451 IFNA17; interferon alpha 17
       3452 IFNA21; interferon alpha 21
       3458 IFNG; interferon gamma
       3559 IL2RA; interleukin 2 receptor subunit alpha
       3560 IL2RB; interleukin 2 receptor subunit beta
       3561 IL2RG; interleukin 2 receptor subunit gamma
       3563 IL3RA; interleukin 3 receptor subunit alpha
       3566 IL4R; interleukin 4 receptor
       1439 CSF2RB; colony stimulating factor 2 receptor subunit beta
       3568 IL5RA; interleukin 5 receptor subunit alpha
       3570 IL6R; interleukin 6 receptor
       3572 IL6ST; interleukin 6 signal transducer
       3575 IL7R; interleukin 7 receptor
       3594 IL12RB1; interleukin 12 receptor subunit beta 1
       3595 IL12RB2; interleukin 12 receptor subunit beta 2
       3597 IL13RA1; interleukin 13 receptor subunit alpha 1
       3601 IL15RA; interleukin 15 receptor subunit alpha
       149233 IL23R; interleukin 23 receptor
       2057 EPOR; erythropoietin receptor
       3454 IFNAR1; interferon alpha and beta receptor subunit 1
       3455 IFNAR2; interferon alpha and beta receptor subunit 2
       3459 IFNGR1; interferon gamma receptor 1
       3460 IFNGR2; interferon gamma receptor 2
       27436 EML4; EMAP like 4
       238 ALK; ALK receptor tyrosine kinase
       10125 RASGRP1; RAS guanyl releasing protein 1
       10235 RASGRP2; RAS guanyl releasing protein 2
       25780 RASGRP3; RAS guanyl releasing protein 3
       115727 RASGRP4; RAS guanyl releasing protein 4
       3716 JAK1; Janus kinase 1
       3717 JAK2; Janus kinase 2
       3718 JAK3; Janus kinase 3
       6774 STAT3; signal transducer and activator of transcription 3
       6772 STAT1; signal transducer and activator of transcription 1
       6773 STAT2; signal transducer and activator of transcription 2
       6775 STAT4; signal transducer and activator of transcription 4
       6778 STAT6; signal transducer and activator of transcription 6
       7422 VEGFA; vascular endothelial growth factor A
       7423 VEGFB; vascular endothelial growth factor B
       5228 PGF; placental growth factor
       7424 VEGFC; vascular endothelial growth factor C
       2277 VEGFD; vascular endothelial growth factor D
       7039 TGFA; transforming growth factor alpha
       1950 EGF; epidermal growth factor
       1956 EGFR; epidermal growth factor receptor
       2064 ERBB2; erb-b2 receptor tyrosine kinase 2
       5154 PDGFA; platelet derived growth factor subunit A
       5155 PDGFB; platelet derived growth factor subunit B
       5156 PDGFRA; platelet derived growth factor receptor alpha
       5159 PDGFRB; platelet derived growth factor receptor beta
       3479 IGF1; insulin like growth factor 1
       3481 IGF2; insulin like growth factor 2
       3480 IGF1R; insulin like growth factor 1 receptor
       4254 KITLG; KIT ligand
       3815 KIT; KIT proto-oncogene, receptor tyrosine kinase
       2323 FLT3LG; fms related receptor tyrosine kinase 3 ligand
       2322 FLT3; fms related receptor tyrosine kinase 3
       3082 HGF; hepatocyte growth factor
       4233 MET; MET proto-oncogene, receptor tyrosine kinase
       2246 FGF1; fibroblast growth factor 1
       2247 FGF2; fibroblast growth factor 2
       2248 FGF3; fibroblast growth factor 3
       2249 FGF4; fibroblast growth factor 4
       8822 FGF17; fibroblast growth factor 17
       2251 FGF6; fibroblast growth factor 6
       2252 FGF7; fibroblast growth factor 7
       2253 FGF8; fibroblast growth factor 8
       2254 FGF9; fibroblast growth factor 9
       2255 FGF10; fibroblast growth factor 10
       8823 FGF16; fibroblast growth factor 16
       2250 FGF5; fibroblast growth factor 5
       8817 FGF18; fibroblast growth factor 18
       26281 FGF20; fibroblast growth factor 20
       27006 FGF22; fibroblast growth factor 22
       9965 FGF19; fibroblast growth factor 19
       26291 FGF21; fibroblast growth factor 21
       8074 FGF23; fibroblast growth factor 23
       2260 FGFR1; fibroblast growth factor receptor 1
       2263 FGFR2; fibroblast growth factor receptor 2
       2261 FGFR3; fibroblast growth factor receptor 3
       2264 FGFR4; fibroblast growth factor receptor 4
       2885 GRB2; growth factor receptor bound protein 2
       6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
       6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
       3265 HRAS; HRas proto-oncogene, GTPase
       3845 KRAS; KRAS proto-oncogene, GTPase
       4893 NRAS; NRAS proto-oncogene, GTPase
       369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
       673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
       5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
       5604 MAP2K1; mitogen-activated protein kinase kinase 1
       5605 MAP2K2; mitogen-activated protein kinase kinase 2
       5594 MAPK1; mitogen-activated protein kinase 1
       5595 MAPK3; mitogen-activated protein kinase 3
       3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
       2353 FOS; Fos proto-oncogene, AP-1 transcription factor subunit
       2113 ETS1; ETS proto-oncogene 1, transcription factor
       4312 MMP1; matrix metallopeptidase 1
       4313 MMP2; matrix metallopeptidase 2
       4318 MMP9; matrix metallopeptidase 9
       3576 CXCL8; C-X-C motif chemokine ligand 8
       1019 CDK4; cyclin dependent kinase 4
       9252 RPS6KA5; ribosomal protein S6 kinase A5
       5979 RET; ret proto-oncogene
       8030 CCDC6; coiled-coil domain containing 6
       8031 NCOA4; nuclear receptor coactivator 4
       4914 NTRK1; neurotrophic receptor tyrosine kinase 1
       7170 TPM3; tropomyosin 3
       7175 TPR; translocated promoter region, nuclear basket protein
       10342 TFG; trafficking from ER to golgi regulator
       11186 RASSF1; Ras association domain family member 1
       83593 RASSF5; Ras association domain family member 5
       6789 STK4; serine/threonine kinase 4
       1612 DAPK1; death associated protein kinase 1
       1613 DAPK3; death associated protein kinase 3
       23604 DAPK2; death associated protein kinase 2
       5335 PLCG1; phospholipase C gamma 1
       5336 PLCG2; phospholipase C gamma 2
       2002 ELK1; ETS transcription factor ELK1
       810 CALML3; calmodulin like 3
       805 CALM2; calmodulin 2
       808 CALM3; calmodulin 3
       801 CALM1; calmodulin 1
       163688 CALML6; calmodulin like 6
       51806 CALML5; calmodulin like 5
       91860 CALML4; calmodulin like 4
       815 CAMK2A; calcium/calmodulin dependent protein kinase II alpha
       817 CAMK2D; calcium/calmodulin dependent protein kinase II delta
       816 CAMK2B; calcium/calmodulin dependent protein kinase II beta
       818 CAMK2G; calcium/calmodulin dependent protein kinase II gamma
       5900 RALGDS; ral guanine nucleotide dissociation stimulator
       5898 RALA; RAS like proto-oncogene A
       5899 RALB; RAS like proto-oncogene B
       10928 RALBP1; ralA binding protein 1
       998 CDC42; cell division cycle 42
       5879 RAC1; Rac family small GTPase 1
       5880 RAC2; Rac family small GTPase 2
       5881 RAC3; Rac family small GTPase 3
       5337 PLD1; phospholipase D1
       5338 PLD2; phospholipase D2
       5599 MAPK8; mitogen-activated protein kinase 8
       5602 MAPK10; mitogen-activated protein kinase 10
       5601 MAPK9; mitogen-activated protein kinase 9
       7849 PAX8; paired box 8
       5468 PPARG; peroxisome proliferator activated receptor gamma
       6256 RXRA; retinoid X receptor alpha
       6257 RXRB; retinoid X receptor beta
       6258 RXRG; retinoid X receptor gamma
       5915 RARB; retinoic acid receptor beta
       2099 ESR1; estrogen receptor 1
       2100 ESR2; estrogen receptor 2
       8648 NCOA1; nuclear receptor coactivator 1
       8202 NCOA3; nuclear receptor coactivator 3
       6667 SP1; Sp1 transcription factor
       5467 PPARD; peroxisome proliferator activated receptor delta
       3728 JUP; junction plakoglobin
       7704 ZBTB16; zinc finger and BTB domain containing 16
       5914 RARA; retinoic acid receptor alpha
       890 CCNA2; cyclin A2
       8900 CCNA1; cyclin A1
       5371 PML; PML nuclear body scaffold
       861 RUNX1; RUNX family transcription factor 1
       862 RUNX1T1; RUNX1 partner transcriptional co-repressor 1
       6688 SPI1; Spi-1 proto-oncogene
       1050 CEBPA; CCAAT enhancer binding protein alpha
       1438 CSF2RA; colony stimulating factor 2 receptor subunit alpha
       1441 CSF3R; colony stimulating factor 3 receptor
       1436 CSF1R; colony stimulating factor 1 receptor
       1029 CDKN2A; cyclin dependent kinase inhibitor 2A
       1869 E2F1; E2F transcription factor 1
       1870 E2F2; E2F transcription factor 2
       1871 E2F3; E2F transcription factor 3
       4149 MAX; MYC associated factor X
       7709 ZBTB17; zinc finger and BTB domain containing 17
       1030 CDKN2B; cyclin dependent kinase inhibitor 2B
       1021 CDK6; cyclin dependent kinase 6
       894 CCND2; cyclin D2
       896 CCND3; cyclin D3
       1163 CKS1B; CDC28 protein kinase regulatory subunit 1B
       1164 CKS2; CDC28 protein kinase regulatory subunit 2
       6500 SKP1; S-phase kinase associated protein 1
       8454 CUL1; cullin 1
       9978 RBX1; ring-box 1
       6502 SKP2; S-phase kinase associated protein 2
       1017 CDK2; cyclin dependent kinase 2
       898 CCNE1; cyclin E1
       9134 CCNE2; cyclin E2
       5925 RB1; RB transcriptional corepressor 1
       1647 GADD45A; growth arrest and DNA damage inducible alpha
       4616 GADD45B; growth arrest and DNA damage inducible beta
       10912 GADD45G; growth arrest and DNA damage inducible gamma
       581 BAX; BCL2 associated X, apoptosis regulator
       578 BAK1; BCL2 antagonist/killer 1
       1643 DDB2; damage specific DNA binding protein 2
       51426 POLK; DNA polymerase kappa
       7015 TERT; telomerase reverse transcriptase
       7012 TERC; telomerase RNA component
       4286 MITF; melanocyte inducing transcription factor
       7040 TGFB1; transforming growth factor beta 1
       7042 TGFB2; transforming growth factor beta 2
       7043 TGFB3; transforming growth factor beta 3
       7046 TGFBR1; transforming growth factor beta receptor 1
       7048 TGFBR2; transforming growth factor beta receptor 2
       4087 SMAD2; SMAD family member 2
       4088 SMAD3; SMAD family member 3
       4089 SMAD4; SMAD family member 4
       2122 MECOM; MDS1 and EVI1 complex locus
       1487 CTBP1; C-terminal binding protein 1
       1488 CTBP2; C-terminal binding protein 2
       3065 HDAC1; histone deacetylase 1
       3066 HDAC2; histone deacetylase 2
       4292 MLH1; mutL homolog 1
       4436 MSH2; mutS homolog 2
       4437 MSH3; mutS homolog 3
       2956 MSH6; mutS homolog 6
       675 BRCA2; BRCA2 DNA repair associated
       5888 RAD51; RAD51 recombinase
       356 FASLG; Fas ligand
       355 FAS; Fas cell surface death receptor
       8772 FADD; Fas associated via death domain
       841 CASP8; caspase 8
       637 BID; BH3 interacting domain death agonist
       5366 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
       27113 BBC3; BCL2 binding component 3
       10018 BCL2L11; BCL2 like 11
       54205 CYCS; cytochrome c, somatic
       317 APAF1; apoptotic peptidase activating factor 1
       840 CASP7; caspase 7
       9817 KEAP1; kelch like ECH associated protein 1
       4780 NFE2L2; nuclear factor, erythroid 2 like 2
       3162 HMOX1; heme oxygenase 1
       1728 NQO1; NAD(P)H quinone dehydrogenase 1
       221357 GSTA5; glutathione S-transferase alpha 5
       2939 GSTA2; glutathione S-transferase alpha 2
       2941 GSTA4; glutathione S-transferase alpha 4
       119391 GSTO2; glutathione S-transferase omega 2
       2948 GSTM4; glutathione S-transferase mu 4
       2953 GSTT2; glutathione S-transferase theta 2 (gene/pseudogene)
       2952 GSTT1; glutathione S-transferase theta 1
       2947 GSTM3; glutathione S-transferase mu 3
       4257 MGST1; microsomal glutathione S-transferase 1
       4259 MGST3; microsomal glutathione S-transferase 3
       2944 GSTM1; glutathione S-transferase mu 1
       2949 GSTM5; glutathione S-transferase mu 5
       4258 MGST2; microsomal glutathione S-transferase 2
       2938 GSTA1; glutathione S-transferase alpha 1
       2946 GSTM2; glutathione S-transferase mu 2
       2940 GSTA3; glutathione S-transferase alpha 3
       9446 GSTO1; glutathione S-transferase omega 1
       653689 GSTT2B; glutathione S-transferase theta 2B
       2950 GSTP1; glutathione S-transferase pi 1
       7296 TXNRD1; thioredoxin reductase 1
       114112 TXNRD3; thioredoxin reductase 3
       10587 TXNRD2; thioredoxin reductase 2
       7428 VHL; von Hippel-Lindau tumor suppressor
       6921 ELOC; elongin C
       6923 ELOB; elongin B
       8453 CUL2; cullin 2
       54583 EGLN1; egl-9 family hypoxia inducible factor 1
       112399 EGLN3; egl-9 family hypoxia inducible factor 3
       112398 EGLN2; egl-9 family hypoxia inducible factor 2
       2271 FH; fumarate hydratase
       3091 HIF1A; hypoxia inducible factor 1 subunit alpha
       2034 EPAS1; endothelial PAS domain protein 1
       405 ARNT; aryl hydrocarbon receptor nuclear translocator
       9915 ARNT2; aryl hydrocarbon receptor nuclear translocator 2
       1387 CREBBP; CREB binding protein
       2033 EP300; E1A binding protein p300
       6513 SLC2A1; solute carrier family 2 member 1
       182 JAG1; jagged canonical Notch ligand 1
       3714 JAG2; jagged canonical Notch ligand 2
       10683 DLL3; delta like canonical Notch ligand 3
       28514 DLL1; delta like canonical Notch ligand 1
       54567 DLL4; delta like canonical Notch ligand 4
       4851 NOTCH1; notch receptor 1
       4853 NOTCH2; notch receptor 2
       4854 NOTCH3; notch receptor 3
       4855 NOTCH4; notch receptor 4
       3280 HES1; hes family bHLH transcription factor 1
       388585 HES5; hes family bHLH transcription factor 5
       26508 HEYL; hes related family bHLH transcription factor with YRPW motif like
       23462 HEY1; hes related family bHLH transcription factor with YRPW motif 1
       23493 HEY2; hes related family bHLH transcription factor with YRPW motif 2
       2324 FLT4; fms related receptor tyrosine kinase 4
       6469 SHH; sonic hedgehog signaling molecule
       5727 PTCH1; patched 1
       6608 SMO; smoothened, frizzled class receptor
       374654 KIF7; kinesin family member 7
       51684 SUFU; SUFU negative regulator of hedgehog signaling
       2735 GLI1; GLI family zinc finger 1
       2736 GLI2; GLI family zinc finger 2
       2737 GLI3; GLI family zinc finger 3
       650 BMP2; bone morphogenetic protein 2
       652 BMP4; bone morphogenetic protein 4
       64399 HHIP; hedgehog interacting protein
       8643 PTCH2; patched 2
       367 AR; androgen receptor
       3320 HSP90AA1; heat shock protein 90 alpha family class A member 1
       3326 HSP90AB1; heat shock protein 90 alpha family class B member 1
       7184 HSP90B1; heat shock protein 90 beta family member 1
       354 KLK3; kallikrein related peptidase 3
K06765 DCC; deleted in colorectal carcinoma
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K08733 APPL1; DCC-interacting protein 13 alpha
K05689 CDH1; cadherin 1, type 1, E-cadherin
K02105 CTNNB1; catenin beta 1
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K02842 FZD9_10; frizzled 9/10
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03096 FRAT2; frequently rearranged in advanced T-cell lymphomas 2
K01313 F2; coagulation factor II (thrombin) [EC:3.4.21.5]
K09821 AGT; angiotensinogen
K03914 F2R; coagulation factor II (thrombin) receptor
K04236 F2RL3; coagulation factor II (thrombin) receptor-like 3
K04289 LPAR1; lysophosphatidic acid receptor 1
K04291 LPAR2; lysophosphatidic acid receptor 2
K04294 LPAR3; lysophosphatidic acid receptor 3
K04275 LPAR4; lysophosphatidic acid receptor 4
K08390 LPAR5; lysophosphatidic acid receptor 5
K04273 LPAR6; lysophosphatidic acid receptor 6
K04166 AGTR1; angiotensin II receptor type 1
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K07532 ARHGEF12; Rho guanine nucleotide exchange factor 12
K12331 ARHGEF11; Rho guanine nucleotide exchange factor 11
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K19464 PLEKHG5; pleckstrin homology domain-containing family G member 5
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K10031 CXCL12; C-X-C motif chemokine 12
K04189 CXCR4; C-X-C chemokine receptor type 4
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04258 PTGER1; prostaglandin E receptor 1
K04259 PTGER2; prostaglandin E receptor 2
K04260 PTGER3; prostaglandin E receptor 3
K04261 PTGER4; prostaglandin E receptor 4
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K05637 LAMA1_2; laminin, alpha 1/2
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K05717 FN1; fibronectin 1
K06481 ITGA2; integrin alpha 2
K06476 ITGA2B; integrin alpha 2B
K06482 ITGA3; integrin alpha 3
K06485 ITGA6; integrin alpha 6
K06487 ITGAV; integrin alpha V
K05719 ITGB1; integrin beta 1
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K09348 NKX3-1; homeobox protein Nkx-3.1
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K04735 RELA; transcription factor p65
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K02161 BCL2; apoptosis regulator Bcl-2
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K03172 TRAF1; TNF receptor-associated factor 1
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K03174 TRAF3; TNF receptor-associated factor 3
K09848 TRAF4; TNF receptor-associated factor 4
K09849 TRAF5; TNF receptor-associated factor 5
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K07201 FOXO1; forkhead box protein O1
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53; tumor protein p53
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K08878 BCR1; breakpoint cluster region protein [EC:2.7.11.1]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K04702 PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
K08806 PIM2; proto-oncogene serine/threonine-protein kinase Pim-2 [EC:2.7.11.1]
K03898 KNG; kininogen
K16366 EDN1; endothelin-1
K03915 BDKRB1; bradykinin receptor B1
K03916 BDKRB2; bradykinin receptor B2
K04197 EDNRA; endothelin receptor type A
K04198 EDNRB; endothelin receptor type B
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K05429 IL2; interleukin 2
K04736 IL3; interleukin 3
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05405 IL6; interleukin 6
K05431 IL7; interleukin 7
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05435 IL13; interleukin 13
K05433 IL15; interleukin 15
K05426 IL23A; interleukin 23 subunit alpha
K05437 EPO; erythropoietin
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K04687 IFNG; interferon gamma
K05068 IL2RA; interleukin 2 receptor alpha
K05069 IL2RB; interleukin 2 receptor beta
K05070 IL2RG; interleukin 2 receptor gamma
K04737 IL3RA; interleukin 3 receptor alpha
K05071 IL4R; interleukin 4 receptor
K04738 CSF2RB; cytokine receptor common subunit beta
K05067 IL5RA. CD125; interleukin 5 receptor alpha
K05055 IL6R; interleukin 6 receptor
K05060 IL6ST; interleukin 6 signal transducer
K05072 IL7R; interleukin 7 receptor
K05063 IL12RB1; interleukin 12 receptor beta-1
K05064 IL12RB2; interleukin 12 receptor beta-2
K05076 IL13RA1; interleukin 13 receptor alpha-1
K05074 IL15RA; interleukin 15 receptor alpha
K05065 IL23R; interleukin 23 receptor
K05079 EPOR; erythropoietin receptor
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K05132 IFNGR1; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K15420 EML4; echinoderm microtubule-associated protein-like 4
K05119 ALK; anaplastic lymphoma kinase [EC:2.7.10.1]
K04350 RASGRP1; RAS guanyl-releasing protein 1
K12361 RASGRP2; RAS guanyl-releasing protein 2
K12362 RASGRP3; RAS guanyl-releasing protein 3
K12363 RASGRP4; RAS guanyl-releasing protein 4
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K11222 STAT4; signal transducer and activator of transcription 4
K11225 STAT6; signal transducer and activator of transcription 6
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05449 VEGFC_D; vascular endothelial growth factor C/D
K08774 TGFA; transforming growth factor, alpha
K04357 EGF; epidermal growth factor
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05459 IGF1; insulin-like growth factor 1
K13769 IGF2; insulin-like growth factor 2
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K05461 KITLG; KIT ligand
K05091 KIT; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05454 FLT3LG; fms-related tyrosine kinase 3 ligand
K05092 FLT3; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K05460 HGF; hepatocyte growth factor
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K02678 ETS1; C-ets-1
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K10030 IL8; interleukin 8
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K04445 RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K09288 CCDC6; coiled-coil domain-containing protein 6
K09289 NCOA4; nuclear receptor coactivator 4
K03176 NTRK1; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K09290 TPM3; tropomyosin 3
K09291 TPR; nucleoprotein TPR
K09292 TFG; protein TFG
K09850 RASSF1; Ras association domain-containing protein 1
K08015 RASSF5; Ras association domain-containing protein 5
K04411 STK4; serine/threonine kinase 4
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04375 ELK1; ETS domain-containing protein Elk-1
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K08773 RALBP1; RalA-binding protein 1
K04393 CDC42; cell division control protein 42
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K09293 PAX8; paired box protein 8
K08530 NR1C3; peroxisome proliferator-activated receptor gamma
K08524 RXRA; retinoid X receptor alpha
K08525 RXRB; retinoid X receptor beta
K08526 RXRG; retinoid X receptor gamma
K08528 RARB; retinoic acid receptor beta
K08550 ESR1; estrogen receptor alpha
K08551 ESR2; estrogen receptor beta
K09101 NCOA1; nuclear receptor coactivator 1 [EC:2.3.1.48]
K11256 NCOA3; nuclear receptor coactivator 3 [EC:2.3.1.48]
K04684 SP1; transcription factor Sp1
K04504 NR1C2; peroxisome proliferator-activated receptor delta
K10056 JUP; junction plakoglobin
K10055 ZBTB16; zinc finger and BTB domain-containing protein 16
K08527 RARA; retinoic acid receptor alpha
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K10054 PML; probable transcription factor PML
K08367 RUNX1; runt-related transcription factor 1
K10053 RUNX1T1; CBFA2/RNUX1 translocation partner 1
K09438 SPI1; transcription factor PU.1
K09055 CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
K05066 CSF2RA; granulocyte-macrophage colony-stimulating factor receptor alpha
K05061 CSF3R; granulocyte colony-stimulating factor receptor
K05090 CSF1R; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04453 MAX; Max protein
K10500 ZBTB17; zinc finger and BTB domain-containing protein 17
K04685 CDKN2B; cyclin-dependent kinase inhibitor 2B
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K02219 CKS1; cyclin-dependent kinase regulatory subunit CKS1
K02219 CKS1; cyclin-dependent kinase regulatory subunit CKS1
K03094 SKP1; S-phase kinase-associated protein 1
K03347 CUL1; cullin 1
K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K06618 RB1; retinoblastoma-associated protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
K22183 TERC; telomerase RNA component
K09455 MITF; microphthalmia-associated transcription factor
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04462 MECOM; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
K04496 CTBP; C-terminal binding protein
K04496 CTBP; C-terminal binding protein
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K08734 MLH1; DNA mismatch repair protein MLH1
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K08775 BRCA2; breast cancer 2 susceptibility protein
K04482 RAD51; DNA repair protein RAD51
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K10131 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
K10132 BBC3; Bcl-2-binding component 3
K16341 BCL2L11; Bcl-2-like protein 11
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K10456 KLHL19; kelch-like protein 19
K05638 NFE2L2; nuclear factor erythroid 2-related factor 2
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K00355 NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K03871 VHL; von Hippel-Lindau disease tumor supressor
K03872 ELOC; elongin-C
K03873 ELOB; elongin-B
K03870 CUL2; cullin 2
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K09095 HIF2A; hypoxia-inducible factor 2 alpha
K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
K15589 ARNT2; aryl hydrocarbon receptor nuclear translocator 2
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K07299 SLC2A1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K06052 JAG1; jagged-1
K21635 JAG2; jagged-2
K06051 DLL; delta
K06051 DLL; delta
K06051 DLL; delta
K02599 NOTCH1; Notch 1
K20994 NOTCH2; Notch 2
K20995 NOTCH3; Notch 3
K20996 NOTCH4; Notch 4
K06054 HES1; hairy and enhancer of split 1
K06055 HES5; hairy and enhancer of split 5
K09091 HEY; hairy and enhancer of split related with YRPW motif
K09091 HEY; hairy and enhancer of split related with YRPW motif
K09091 HEY; hairy and enhancer of split related with YRPW motif
K05097 FLT4; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K11988 SHH; sonic hedgehog
K06225 PTCH1; patched 1
K06226 SMO; smoothened
K18806 KIF7; kinesin family member 7
K06229 SUFU; suppressor of fused
K16797 GLI1; zinc finger protein GLI1
K16798 GLI2; zinc finger protein GLI2
K06230 GLI3; zinc finger protein GLI3
K21283 BMP2; bone morphogenetic protein 2
K04662 BMP4; bone morphogenetic protein 4
K06231 HHIP; hedgehog interacting protein
K11101 PTCH2; patched 2
K08557 AR; androgen receptor
K04079 HSP90A; molecular chaperone HtpG
K04079 HSP90A; molecular chaperone HtpG
K09487 HSP90B; heat shock protein 90kDa beta
K01351 KLK3; semenogelase [EC:3.4.21.77]
     05202 Transcriptional misregulation in cancer [PATH:hsa05202]
     05206 MicroRNAs in cancer [PATH:hsa05206]
     05205 Proteoglycans in cancer [PATH:hsa05205]
     05204 Chemical carcinogenesis [PATH:hsa05204]
     05203 Viral carcinogenesis [PATH:hsa05203]
     05230 Central carbon metabolism in cancer [PATH:hsa05230]
     05231 Choline metabolism in cancer [PATH:hsa05231]
     05235 PD-L1 expression and PD-1 checkpoint pathway in cancer [PATH:hsa05235]
 
   09162 Cancer: specific types
     05210 Colorectal cancer [PATH:hsa05210]
     05212 Pancreatic cancer [PATH:hsa05212]
     05225 Hepatocellular carcinoma [PATH:hsa05225]
     05226 Gastric cancer [PATH:hsa05226]
     05214 Glioma [PATH:hsa05214]
     05216 Thyroid cancer [PATH:hsa05216]
     05221 Acute myeloid leukemia [PATH:hsa05221]
     05220 Chronic myeloid leukemia [PATH:hsa05220]
     05217 Basal cell carcinoma [PATH:hsa05217]
     05218 Melanoma [PATH:hsa05218]
     05211 Renal cell carcinoma [PATH:hsa05211]
       3091 HIF1A; hypoxia inducible factor 1 subunit alpha
       2034 EPAS1; endothelial PAS domain protein 1
       54583 EGLN1; egl-9 family hypoxia inducible factor 1
       112399 EGLN3; egl-9 family hypoxia inducible factor 3
       112398 EGLN2; egl-9 family hypoxia inducible factor 2
       7428 VHL; von Hippel-Lindau tumor suppressor
       6921 ELOC; elongin C
       6923 ELOB; elongin B
       9978 RBX1; ring-box 1
       8453 CUL2; cullin 2
       405 ARNT; aryl hydrocarbon receptor nuclear translocator
       9915 ARNT2; aryl hydrocarbon receptor nuclear translocator 2
       1387 CREBBP; CREB binding protein
       2033 EP300; E1A binding protein p300
       6513 SLC2A1; solute carrier family 2 member 1
       7422 VEGFA; vascular endothelial growth factor A
       7040 TGFB1; transforming growth factor beta 1
       7042 TGFB2; transforming growth factor beta 2
       7043 TGFB3; transforming growth factor beta 3
       5155 PDGFB; platelet derived growth factor subunit B
       7039 TGFA; transforming growth factor alpha
       3082 HGF; hepatocyte growth factor
       4233 MET; MET proto-oncogene, receptor tyrosine kinase
       2549 GAB1; GRB2 associated binding protein 1
       5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
       5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
       8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
       207 AKT1; AKT serine/threonine kinase 1
       208 AKT2; AKT serine/threonine kinase 2
       10000 AKT3; AKT serine/threonine kinase 3
       572 BAD; BCL2 associated agonist of cell death
       1398 CRK; CRK proto-oncogene, adaptor protein
       1399 CRKL; CRK like proto-oncogene, adaptor protein
       2889 RAPGEF1; Rap guanine nucleotide exchange factor 1
       5906 RAP1A; RAP1A, member of RAS oncogene family
       5908 RAP1B; RAP1B, member of RAS oncogene family
       5781 PTPN11; protein tyrosine phosphatase non-receptor type 11
       2885 GRB2; growth factor receptor bound protein 2
       6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
       6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
       3265 HRAS; HRas proto-oncogene, GTPase
       3845 KRAS; KRAS proto-oncogene, GTPase
       4893 NRAS; NRAS proto-oncogene, GTPase
       369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
       673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
       5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
       5604 MAP2K1; mitogen-activated protein kinase kinase 1
       5605 MAP2K2; mitogen-activated protein kinase kinase 2
       5594 MAPK1; mitogen-activated protein kinase 1
       5595 MAPK3; mitogen-activated protein kinase 3
       2113 ETS1; ETS proto-oncogene 1, transcription factor
       3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
       5879 RAC1; Rac family small GTPase 1
       998 CDC42; cell division cycle 42
       5058 PAK1; p21 (RAC1) activated kinase 1
       5062 PAK2; p21 (RAC1) activated kinase 2
       5063 PAK3; p21 (RAC1) activated kinase 3
       10298 PAK4; p21 (RAC1) activated kinase 4
       57144 PAK5; p21 (RAC1) activated kinase 5
       56924 PAK6; p21 (RAC1) activated kinase 6
       106821730 BUB1B-PAK6; BUB1B-PAK6 readthrough
       5546 PRCC; proline rich mitotic checkpoint control factor
       7030 TFE3; transcription factor binding to IGHM enhancer 3
       1026 CDKN1A; cyclin dependent kinase inhibitor 1A
       2271 FH; fumarate hydratase
       201163 FLCN; folliculin
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K09095 HIF2A; hypoxia-inducible factor 2 alpha
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K03871 VHL; von Hippel-Lindau disease tumor supressor
K03872 ELOC; elongin-C
K03873 ELOB; elongin-B
K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K03870 CUL2; cullin 2
K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
K15589 ARNT2; aryl hydrocarbon receptor nuclear translocator 2
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K07299 SLC2A1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K05448 VEGFA; vascular endothelial growth factor A
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K17386 PDGFB; platelet-derived growth factor subunit B
K08774 TGFA; transforming growth factor, alpha
K05460 HGF; hepatocyte growth factor
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K09593 GAB1; GRB2-associated-binding protein 1
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K06277 RAPGEF1; Rap guanine nucleotide exchange factor 1
K04353 RAP1A; Ras-related protein Rap-1A
K07836 RAP1B; Ras-related protein Rap-1B
K07293 PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K02678 ETS1; C-ets-1
K04448 JUN; transcription factor AP-1
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K04393 CDC42; cell division control protein 42
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K04410 PAK2; p21-activated kinase 2 [EC:2.7.11.1]
K05733 PAK3; p21-activated kinase 3 [EC:2.7.11.1]
K05734 PAK4; p21-activated kinase 4 [EC:2.7.11.1]
K05736 PAK5; p21-activated kinase 5 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K05735 PAK6; p21-activated kinase 6 [EC:2.7.11.1]
K13105 PRCC; proline-rich protein PRCC
K09105 TFE3; transcription factor E3
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
K09594 FLCN; folliculin
     05219 Bladder cancer [PATH:hsa05219]
     05215 Prostate cancer [PATH:hsa05215]
     05213 Endometrial cancer [PATH:hsa05213]
     05224 Breast cancer [PATH:hsa05224]
     05222 Small cell lung cancer [PATH:hsa05222]
     05223 Non-small cell lung cancer [PATH:hsa05223]
 
   09163 Immune disease
 
   09164 Neurodegenerative disease
 
   09165 Substance dependence
 
   09166 Cardiovascular disease
 
   09167 Endocrine and metabolic disease
 
   09171 Infectious disease: bacterial
 
   09172 Infectious disease: viral
 
   09174 Infectious disease: parasitic
 
   09175 Drug resistance: antimicrobial
 
   09176 Drug resistance: antineoplastic
 
 09180 Brite Hierarchies
 
 09190 Not Included in Pathway or Brite

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: January 27, 2021