KEGG Orthology (KO) - Homo sapiens (human)

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     KO
 09100 Metabolism
 
   09101 Carbohydrate metabolism
 
   09102 Energy metabolism
 
   09103 Lipid metabolism
 
   09104 Nucleotide metabolism
 
   09105 Amino acid metabolism
     00250 Alanine, aspartate and glutamate metabolism [PATH:hsa00250]
     00260 Glycine, serine and threonine metabolism [PATH:hsa00260]
     00270 Cysteine and methionine metabolism [PATH:hsa00270]
     00280 Valine, leucine and isoleucine degradation [PATH:hsa00280]
     00290 Valine, leucine and isoleucine biosynthesis [PATH:hsa00290]
     00300 Lysine biosynthesis
     00310 Lysine degradation [PATH:hsa00310]
     00220 Arginine biosynthesis [PATH:hsa00220]
     00330 Arginine and proline metabolism [PATH:hsa00330]
     00340 Histidine metabolism [PATH:hsa00340]
     00350 Tyrosine metabolism [PATH:hsa00350]
       2805 GOT1; glutamic-oxaloacetic transaminase 1
       137362 GOT1L1; glutamic-oxaloacetic transaminase 1 like 1
       2806 GOT2; glutamic-oxaloacetic transaminase 2
       6898 TAT; tyrosine aminotransferase
       259307 IL4I1; interleukin 4 induced 1
       3242 HPD; 4-hydroxyphenylpyruvate dioxygenase
       3081 HGD; homogentisate 1,2-dioxygenase
       2954 GSTZ1; glutathione S-transferase zeta 1
       2184 FAH; fumarylacetoacetate hydrolase
       7299 TYR; tyrosinase
       7054 TH; tyrosine hydroxylase
       1638 DCT; dopachrome tautomerase
       7306 TYRP1; tyrosinase related protein 1
       1644 DDC; dopa decarboxylase
       1621 DBH; dopamine beta-hydroxylase
       5409 PNMT; phenylethanolamine N-methyltransferase
       1312 COMT; catechol-O-methyltransferase
       220074 LRTOMT; leucine rich transmembrane and O-methyltransferase domain containing
       4129 MAOB; monoamine oxidase B
       4128 MAOA; monoamine oxidase A
       8639 AOC3; amine oxidase copper containing 3
       314 AOC2; amine oxidase copper containing 2
       221 ALDH3B1; aldehyde dehydrogenase 3 family member B1
       222 ALDH3B2; aldehyde dehydrogenase 3 family member B2
       218 ALDH3A1; aldehyde dehydrogenase 3 family member A1
       124 ADH1A; alcohol dehydrogenase 1A (class I), alpha polypeptide
       125 ADH1B; alcohol dehydrogenase 1B (class I), beta polypeptide
       126 ADH1C; alcohol dehydrogenase 1C (class I), gamma polypeptide
       131 ADH7; alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
       127 ADH4; alcohol dehydrogenase 4 (class II), pi polypeptide
       128 ADH5; alcohol dehydrogenase 5 (class III), chi polypeptide
       130 ADH6; alcohol dehydrogenase 6 (class V)
       7173 TPO; thyroid peroxidase
       316 AOX1; aldehyde oxidase 1
       81889 FAHD1; fumarylacetoacetate hydrolase domain containing 1
       4282 MIF; macrophage migration inhibitory factor
K14454 GOT1; aspartate aminotransferase, cytoplasmic [EC:2.6.1.1]
K14454 GOT1; aspartate aminotransferase, cytoplasmic [EC:2.6.1.1]
K14455 GOT2; aspartate aminotransferase, mitochondrial [EC:2.6.1.1]
K00815 TAT; tyrosine aminotransferase [EC:2.6.1.5]
K03334 IL4I1; L-amino-acid oxidase [EC:1.4.3.2]
K00457 HPD; 4-hydroxyphenylpyruvate dioxygenase [EC:1.13.11.27]
K00451 HGD; homogentisate 1,2-dioxygenase [EC:1.13.11.5]
K01800 maiA; maleylacetoacetate isomerase [EC:5.2.1.2]
K01555 FAH; fumarylacetoacetase [EC:3.7.1.2]
K00505 TYR; tyrosinase [EC:1.14.18.1]
K00501 TH; tyrosine 3-monooxygenase [EC:1.14.16.2]
K01827 DCT; dopachrome tautomerase [EC:5.3.3.12]
K00506 TYRP1; tyrosinase-related protein 1 [EC:1.14.18.-]
K01593 DDC; aromatic-L-amino-acid/L-tryptophan decarboxylase [EC:4.1.1.28 4.1.1.105]
K00503 DBH; dopamine beta-monooxygenase [EC:1.14.17.1]
K00553 PNMT; phenylethanolamine N-methyltransferase [EC:2.1.1.28]
K00545 COMT; catechol O-methyltransferase [EC:2.1.1.6]
K00545 COMT; catechol O-methyltransferase [EC:2.1.1.6]
K00274 MAO; monoamine oxidase [EC:1.4.3.4]
K00274 MAO; monoamine oxidase [EC:1.4.3.4]
K00276 AOC3; primary-amine oxidase [EC:1.4.3.21]
K00276 AOC3; primary-amine oxidase [EC:1.4.3.21]
K00129 ALDH3; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K00129 ALDH3; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K00129 ALDH3; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K13951 ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]
K13951 ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]
K13951 ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]
K13951 ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]
K13980 ADH4; alcohol dehydrogenase 4 [EC:1.1.1.1]
K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]
K13952 ADH6; alcohol dehydrogenase 6 [EC:1.1.1.1]
K00431 TPO; thyroid peroxidase [EC:1.11.1.8]
K00157 AOX; aldehyde oxidase [EC:1.2.3.1]
K01557 FAHD1; acylpyruvate hydrolase [EC:3.7.1.5]
K07253 MIF; phenylpyruvate tautomerase [EC:5.3.2.1]
     00360 Phenylalanine metabolism [PATH:hsa00360]
     00380 Tryptophan metabolism [PATH:hsa00380]
     00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:hsa00400]
 
   09106 Metabolism of other amino acids
 
   09107 Glycan biosynthesis and metabolism
 
   09108 Metabolism of cofactors and vitamins
 
   09109 Metabolism of terpenoids and polyketides
 
   09110 Biosynthesis of other secondary metabolites
 
   09111 Xenobiotics biodegradation and metabolism
 
   09112 Not included in regular maps
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
 09140 Cellular Processes
 
 09150 Organismal Systems
 
   09151 Immune system
 
   09152 Endocrine system
     04911 Insulin secretion [PATH:hsa04911]
     04910 Insulin signaling pathway [PATH:hsa04910]
     04922 Glucagon signaling pathway [PATH:hsa04922]
     04923 Regulation of lipolysis in adipocytes [PATH:hsa04923]
     04920 Adipocytokine signaling pathway [PATH:hsa04920]
     03320 PPAR signaling pathway [PATH:hsa03320]
     04929 GnRH secretion [PATH:hsa04929]
     04912 GnRH signaling pathway [PATH:hsa04912]
     04913 Ovarian steroidogenesis [PATH:hsa04913]
     04915 Estrogen signaling pathway [PATH:hsa04915]
     04914 Progesterone-mediated oocyte maturation [PATH:hsa04914]
     04917 Prolactin signaling pathway [PATH:hsa04917]
     04921 Oxytocin signaling pathway [PATH:hsa04921]
     04926 Relaxin signaling pathway [PATH:hsa04926]
     04935 Growth hormone synthesis, secretion and action [PATH:hsa04935]
     04918 Thyroid hormone synthesis [PATH:hsa04918]
     04919 Thyroid hormone signaling pathway [PATH:hsa04919]
     04928 Parathyroid hormone synthesis, secretion and action [PATH:hsa04928]
     04916 Melanogenesis [PATH:hsa04916]
       5443 POMC; proopiomelanocortin
       434 ASIP; agouti signaling protein
       4157 MC1R; melanocortin 1 receptor
       2778 GNAS; GNAS complex locus
       107 ADCY1; adenylate cyclase 1
       108 ADCY2; adenylate cyclase 2
       109 ADCY3; adenylate cyclase 3
       196883 ADCY4; adenylate cyclase 4
       111 ADCY5; adenylate cyclase 5
       112 ADCY6; adenylate cyclase 6
       113 ADCY7; adenylate cyclase 7
       114 ADCY8; adenylate cyclase 8
       115 ADCY9; adenylate cyclase 9
       5566 PRKACA; protein kinase cAMP-activated catalytic subunit alpha
       5567 PRKACB; protein kinase cAMP-activated catalytic subunit beta
       5568 PRKACG; protein kinase cAMP-activated catalytic subunit gamma
       1385 CREB1; cAMP responsive element binding protein 1
       10488 CREB3; cAMP responsive element binding protein 3
       90993 CREB3L1; cAMP responsive element binding protein 3 like 1
       64764 CREB3L2; cAMP responsive element binding protein 3 like 2
       84699 CREB3L3; cAMP responsive element binding protein 3 like 3
       148327 CREB3L4; cAMP responsive element binding protein 3 like 4
       1387 CREBBP; CREB binding protein
       2033 EP300; E1A binding protein p300
       4286 MITF; melanocyte inducing transcription factor
       7471 WNT1; Wnt family member 1
       7472 WNT2; Wnt family member 2
       7482 WNT2B; Wnt family member 2B
       7473 WNT3; Wnt family member 3
       89780 WNT3A; Wnt family member 3A
       54361 WNT4; Wnt family member 4
       7474 WNT5A; Wnt family member 5A
       81029 WNT5B; Wnt family member 5B
       7475 WNT6; Wnt family member 6
       7476 WNT7A; Wnt family member 7A
       7477 WNT7B; Wnt family member 7B
       7478 WNT8A; Wnt family member 8A
       7479 WNT8B; Wnt family member 8B
       7483 WNT9A; Wnt family member 9A
       7484 WNT9B; Wnt family member 9B
       7480 WNT10B; Wnt family member 10B
       80326 WNT10A; Wnt family member 10A
       7481 WNT11; Wnt family member 11
       51384 WNT16; Wnt family member 16
       8321 FZD1; frizzled class receptor 1
       8324 FZD7; frizzled class receptor 7
       2535 FZD2; frizzled class receptor 2
       7976 FZD3; frizzled class receptor 3
       8322 FZD4; frizzled class receptor 4
       7855 FZD5; frizzled class receptor 5
       8325 FZD8; frizzled class receptor 8
       8323 FZD6; frizzled class receptor 6
       11211 FZD10; frizzled class receptor 10
       8326 FZD9; frizzled class receptor 9
       2775 GNAO1; G protein subunit alpha o1
       2776 GNAQ; G protein subunit alpha q
       1857 DVL3; dishevelled segment polarity protein 3
       1856 DVL2; dishevelled segment polarity protein 2
       1855 DVL1; dishevelled segment polarity protein 1
       2932 GSK3B; glycogen synthase kinase 3 beta
       1499 CTNNB1; catenin beta 1
       6932 TCF7; transcription factor 7
       83439 TCF7L1; transcription factor 7 like 1
       6934 TCF7L2; transcription factor 7 like 2
       51176 LEF1; lymphoid enhancer binding factor 1
       4254 KITLG; KIT ligand
       3815 KIT; KIT proto-oncogene, receptor tyrosine kinase
       3265 HRAS; HRas proto-oncogene, GTPase
       3845 KRAS; KRAS proto-oncogene, GTPase
       4893 NRAS; NRAS proto-oncogene, GTPase
       5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
       5604 MAP2K1; mitogen-activated protein kinase kinase 1
       5605 MAP2K2; mitogen-activated protein kinase kinase 2
       5594 MAPK1; mitogen-activated protein kinase 1
       5595 MAPK3; mitogen-activated protein kinase 3
       7299 TYR; tyrosinase
       7306 TYRP1; tyrosinase related protein 1
       1638 DCT; dopachrome tautomerase
       1906 EDN1; endothelin 1
       1910 EDNRB; endothelin receptor type B
       2770 GNAI1; G protein subunit alpha i1
       2773 GNAI3; G protein subunit alpha i3
       2771 GNAI2; G protein subunit alpha i2
       23236 PLCB1; phospholipase C beta 1
       5330 PLCB2; phospholipase C beta 2
       5331 PLCB3; phospholipase C beta 3
       5332 PLCB4; phospholipase C beta 4
       810 CALML3; calmodulin like 3
       805 CALM2; calmodulin 2
       808 CALM3; calmodulin 3
       801 CALM1; calmodulin 1
       163688 CALML6; calmodulin like 6
       51806 CALML5; calmodulin like 5
       91860 CALML4; calmodulin like 4
       815 CAMK2A; calcium/calmodulin dependent protein kinase II alpha
       817 CAMK2D; calcium/calmodulin dependent protein kinase II delta
       816 CAMK2B; calcium/calmodulin dependent protein kinase II beta
       818 CAMK2G; calcium/calmodulin dependent protein kinase II gamma
       5578 PRKCA; protein kinase C alpha
       5579 PRKCB; protein kinase C beta
       5582 PRKCG; protein kinase C gamma
K05228 POMC; proopiomelanocortin
K08725 ASIP; agouti signaling protein
K04199 MC1R; melanocortin 1 receptor
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K09455 MITF; microphthalmia-associated transcription factor
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K02842 FZD9_10; frizzled 9/10
K04534 GNAO; guanine nucleotide-binding protein G(o) subunit alpha
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02105 CTNNB1; catenin beta 1
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K05461 KITLG; KIT ligand
K05091 KIT; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K00505 TYR; tyrosinase [EC:1.14.18.1]
K00506 TYRP1; tyrosinase-related protein 1 [EC:1.14.18.-]
K01827 DCT; dopachrome tautomerase [EC:5.3.3.12]
K16366 EDN1; endothelin-1
K04198 EDNRB; endothelin receptor type B
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
     04924 Renin secretion [PATH:hsa04924]
     04614 Renin-angiotensin system [PATH:hsa04614]
     04925 Aldosterone synthesis and secretion [PATH:hsa04925]
     04927 Cortisol synthesis and secretion [PATH:hsa04927]
 
   09153 Circulatory system
 
   09154 Digestive system
 
   09155 Excretory system
 
   09156 Nervous system
 
   09157 Sensory system
 
   09158 Development and regeneration
 
   09149 Aging
 
   09159 Environmental adaptation
 
 09160 Human Diseases
 
 09180 Brite Hierarchies
 
 09190 Not Included in Pathway or Brite

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Last updated: April 24, 2024