KEGG Orthology (KO) - Homo sapiens (human)

[ Brite menu | Download htext | Download json | Help ]
Search

1st Level  2nd Level  3rd Level  4th Level 

     KO
 09100 Metabolism
 
   09101 Carbohydrate metabolism
 
   09102 Energy metabolism
 
   09103 Lipid metabolism
 
   09104 Nucleotide metabolism
     00230 Purine metabolism [PATH:hsa00230]
       53343 NUDT9; nudix hydrolase 9
       56985 ADPRM; ADP-ribose/CDP-alcohol diphosphatase, manganese dependent
       11164 NUDT5; nudix hydrolase 5
       5236 PGM1; phosphoglucomutase 1
       55276 PGM2; phosphoglucomutase 2
       221823 PRPS1L1; phosphoribosyl pyrophosphate synthetase 1 like 1
       5634 PRPS2; phosphoribosyl pyrophosphate synthetase 2
       5631 PRPS1; phosphoribosyl pyrophosphate synthetase 1
       5471 PPAT; phosphoribosyl pyrophosphate amidotransferase
       2618 GART; phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
       5198 PFAS; phosphoribosylformylglycinamidine synthase
       10606 PAICS; phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
       158 ADSL; adenylosuccinate lyase
       471 ATIC; 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
       353 APRT; adenine phosphoribosyltransferase
       22978 NT5C2; 5'-nucleotidase, cytosolic II
       84618 NT5C1A; 5'-nucleotidase, cytosolic IA
       93034 NT5C1B; 5'-nucleotidase, cytosolic IB
       30833 NT5C; 5', 3'-nucleotidase, cytosolic
       56953 NT5M; 5',3'-nucleotidase, mitochondrial
       100526794 NT5C1B-RDH14; NT5C1B-RDH14 readthrough
       4907 NT5E; 5'-nucleotidase ecto
       51251 NT5C3A; 5'-nucleotidase, cytosolic IIIA
       115024 NT5C3B; 5'-nucleotidase, cytosolic IIIB
       4860 PNP; purine nucleoside phosphorylase
       3251 HPRT1; hypoxanthine phosphoribosyltransferase 1
       3614 IMPDH1; inosine monophosphate dehydrogenase 1
       3615 IMPDH2; inosine monophosphate dehydrogenase 2
       10201 NME6; NME/NM23 nucleoside diphosphate kinase 6
       29922 NME7; NME/NM23 family member 7
       4831 NME2; NME/NM23 nucleoside diphosphate kinase 2
       4833 NME4; NME/NM23 nucleoside diphosphate kinase 4
       4830 NME1; NME/NM23 nucleoside diphosphate kinase 1
       4832 NME3; NME/NM23 nucleoside diphosphate kinase 3
       654364 NME1-NME2; NME1-NME2 readthrough
       221264 AK9; adenylate kinase 9
       956 ENTPD3; ectonucleoside triphosphate diphosphohydrolase 3
       377841 ENTPD8; ectonucleoside triphosphate diphosphohydrolase 8
       953 ENTPD1; ectonucleoside triphosphate diphosphohydrolase 1
       124583 CANT1; calcium activated nucleotidase 1
       9583 ENTPD4; ectonucleoside triphosphate diphosphohydrolase 4
       957 ENTPD5; ectonucleoside triphosphate diphosphohydrolase 5 (inactive)
       955 ENTPD6; ectonucleoside triphosphate diphosphohydrolase 6
       131870 NUDT16; nudix hydrolase 16
       3704 ITPA; inosine triphosphatase
       7498 XDH; xanthine dehydrogenase
       318 NUDT2; nudix hydrolase 2
       8833 GMPS; guanine monophosphate synthase
       2766 GMPR; guanosine monophosphate reductase
       51292 GMPR2; guanosine monophosphate reductase 2
       9615 GDA; guanine deaminase
       2987 GUK1; guanylate kinase 1
       5315 PKM; pyruvate kinase M1/2
       5313 PKLR; pyruvate kinase L/R
       6240 RRM1; ribonucleotide reductase catalytic subunit M1
       50484 RRM2B; ribonucleotide reductase regulatory TP53 inducible subunit M2B
       6241 RRM2; ribonucleotide reductase regulatory subunit M2
       1716 DGUOK; deoxyguanosine kinase
       374659 HDDC3; HD domain containing 3
       58497 PRUNE1; prune exopolyphosphatase 1
       107 ADCY1; adenylate cyclase 1
       108 ADCY2; adenylate cyclase 2
       109 ADCY3; adenylate cyclase 3
       196883 ADCY4; adenylate cyclase 4
       111 ADCY5; adenylate cyclase 5
       112 ADCY6; adenylate cyclase 6
       113 ADCY7; adenylate cyclase 7
       114 ADCY8; adenylate cyclase 8
       115 ADCY9; adenylate cyclase 9
       55811 ADCY10; adenylate cyclase 10
       2977 GUCY1A2; guanylate cyclase 1 soluble subunit alpha 2
       2982 GUCY1A1; guanylate cyclase 1 soluble subunit alpha 1
       2983 GUCY1B1; guanylate cyclase 1 soluble subunit beta 1
       2984 GUCY2C; guanylate cyclase 2C
       3000 GUCY2D; guanylate cyclase 2D, retinal
       2986 GUCY2F; guanylate cyclase 2F, retinal
       4881 NPR1; natriuretic peptide receptor 1
       4882 NPR2; natriuretic peptide receptor 2
       5136 PDE1A; phosphodiesterase 1A
       5153 PDE1B; phosphodiesterase 1B
       5137 PDE1C; phosphodiesterase 1C
       5138 PDE2A; phosphodiesterase 2A
       5139 PDE3A; phosphodiesterase 3A
       5140 PDE3B; phosphodiesterase 3B
       8654 PDE5A; phosphodiesterase 5A
       5145 PDE6A; phosphodiesterase 6A
       5158 PDE6B; phosphodiesterase 6B
       5146 PDE6C; phosphodiesterase 6C
       5147 PDE6D; phosphodiesterase 6D
       5148 PDE6G; phosphodiesterase 6G
       5149 PDE6H; phosphodiesterase 6H
       5152 PDE9A; phosphodiesterase 9A
       10846 PDE10A; phosphodiesterase 10A
       50940 PDE11A; phosphodiesterase 11A
       122622 ADSS1; adenylosuccinate synthase 1
       159 ADSS2; adenylosuccinate synthase 2
       271 AMPD2; adenosine monophosphate deaminase 2
       272 AMPD3; adenosine monophosphate deaminase 3
       270 AMPD1; adenosine monophosphate deaminase 1
       132 ADK; adenosine kinase
       1633 DCK; deoxycytidine kinase
       100 ADA; adenosine deaminase
       51816 ADA2; adenosine deaminase 2
       122481 AK7; adenylate kinase 7
       205 AK4; adenylate kinase 4
       26289 AK5; adenylate kinase 5
       204 AK2; adenylate kinase 2
       203 AK1; adenylate kinase 1
       390877 adenylate kinase isoenzyme 1-like
       158067 AK8; adenylate kinase 8
       102157402 AK6; adenylate kinase 6
       50808 AK3; adenylate kinase 3
       954 ENTPD2; ectonucleoside triphosphate diphosphohydrolase 2
       84284 NTPCR; nucleoside-triphosphatase, cancer-related
       5141 PDE4A; phosphodiesterase 4A
       5142 PDE4B; phosphodiesterase 4B
       5143 PDE4C; phosphodiesterase 4C
       5144 PDE4D; phosphodiesterase 4D
       5150 PDE7A; phosphodiesterase 7A
       27115 PDE7B; phosphodiesterase 7B
       8622 PDE8B; phosphodiesterase 8B
       5151 PDE8A; phosphodiesterase 8A
       2272 FHIT; fragile histidine triad diadenosine triphosphatase
       22875 ENPP4; ectonucleotide pyrophosphatase/phosphodiesterase 4
       9060 PAPSS2; 3'-phosphoadenosine 5'-phosphosulfate synthase 2
       9061 PAPSS1; 3'-phosphoadenosine 5'-phosphosulfate synthase 1
       5167 ENPP1; ectonucleotide pyrophosphatase/phosphodiesterase 1
       5169 ENPP3; ectonucleotide pyrophosphatase/phosphodiesterase 3
       646625 URAD; ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase
       55821 ALLC; allantoicase
K13988 NUDT9; ADP-ribose pyrophosphatase [EC:3.6.1.13]
K01517 ADPRM; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [EC:3.6.1.13 3.6.1.16 3.6.1.53]
K13987 NUDT5; ADP-sugar pyrophosphatase / 8-oxo-dGDP phosphatase / ADP-D-ribose pyrophosphorylase [EC:3.6.1.13 3.6.1.58 2.7.7.96]
K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
K15779 PGM2; phosphoglucomutase / phosphopentomutase [EC:5.4.2.2 5.4.2.7]
K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
K11787 GART; phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.4.13 2.1.2.2 6.3.3.1]
K01952 PFAS; phosphoribosylformylglycinamidine synthase [EC:6.3.5.3]
K01587 PAICS; phosphoribosylaminoimidazole carboxylase / phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:4.1.1.21 6.3.2.6]
K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
K01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]
K01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]
K01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]
K01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]
K01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]
K01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]
K19970 NT5E; 5'-nucleotidase [EC:3.1.3.5]
K24242 NT5C3; cytosolic 5'-nucleotidase 3 [EC:3.1.3.5 3.1.3.-]
K24242 NT5C3; cytosolic 5'-nucleotidase 3 [EC:3.1.3.5 3.1.3.-]
K03783 punA; purine-nucleoside phosphorylase [EC:2.4.2.1]
K00760 hprT; hypoxanthine phosphoribosyltransferase [EC:2.4.2.8]
K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
K18533 AK9; adenylate/nucleoside-diphosphate kinase [EC:2.7.4.3 2.7.4.6]
K01510 ENTPD1_3_8; apyrase [EC:3.6.1.5]
K01510 ENTPD1_3_8; apyrase [EC:3.6.1.5]
K01510 ENTPD1_3_8; apyrase [EC:3.6.1.5]
K12304 CANT1; soluble calcium-activated nucleotidase 1 [EC:3.6.1.6]
K12305 ENTPD4; ectonucleoside triphosphate diphosphohydrolase 4 [EC:3.6.1.6]
K01511 ENTPD5_6; ectonucleoside triphosphate diphosphohydrolase 5/6 [EC:3.6.1.6]
K01511 ENTPD5_6; ectonucleoside triphosphate diphosphohydrolase 5/6 [EC:3.6.1.6]
K16855 NUDT16; U8 snoRNA-decapping enzyme [EC:3.6.1.62 3.6.1.64]
K01519 ITPA; inosine triphosphate pyrophosphatase [EC:3.6.1.-]
K00106 XDH; xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2]
K01518 NUDT2; bis(5'-nucleosidyl)-tetraphosphatase [EC:3.6.1.17]
K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
K00364 E1.7.1.7; GMP reductase [EC:1.7.1.7]
K00364 E1.7.1.7; GMP reductase [EC:1.7.1.7]
K01487 E3.5.4.3; guanine deaminase [EC:3.5.4.3]
K00942 E2.7.4.8; guanylate kinase [EC:2.7.4.8]
K00873 PK; pyruvate kinase [EC:2.7.1.40]
K12406 PKLR; pyruvate kinase isozymes R/L [EC:2.7.1.40]
K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K00904 DGUOK; deoxyguanosine kinase [EC:2.7.1.113]
K21138 HDDC3; guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [EC:3.1.7.2]
K01514 PRUNE; exopolyphosphatase [EC:3.6.1.11]
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K11265 ADCY10; adenylate cyclase 10 [EC:4.6.1.1]
K12318 GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
K12318 GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
K12319 GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
K12320 GUCY2C; heat-stable enterotoxin receptor [EC:4.6.1.2]
K12321 GUCY2D_E; guanylate cyclase 2D/E [EC:4.6.1.2]
K12322 GUCY2F; guanylate cyclase 2F [EC:4.6.1.2]
K12323 ANPRA; atrial natriuretic peptide receptor A [EC:4.6.1.2]
K12324 ANPRB; atrial natriuretic peptide receptor B [EC:4.6.1.2]
K13755 PDE1; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase [EC:3.1.4.17]
K13755 PDE1; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase [EC:3.1.4.17]
K13755 PDE1; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase [EC:3.1.4.17]
K18283 PDE2A; cGMP-dependent 3',5'-cyclic phosphodiesterase [EC:3.1.4.17]
K19021 PDE3A; cGMP-inhibited 3',5'-cyclic phosphodiesterase A [EC:3.1.4.17]
K13296 PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B [EC:3.1.4.17]
K13762 PDE5; cGMP-specific 3',5'-cyclic phosphodiesterase [EC:3.1.4.35]
K08718 PDE6A; rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha [EC:3.1.4.35]
K13756 PDE6B; rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta [EC:3.1.4.35]
K13757 PDE6C; cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' [EC:3.1.4.35]
K13758 PDE6D; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta
K13759 PDE6G; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma
K13760 PDE6H; retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma
K13761 PDE9; high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9 [EC:3.1.4.35]
K18438 PDE10; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:3.1.4.17 3.1.4.35]
K13298 PDE11; dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11 [EC:3.1.4.17 3.1.4.35]
K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
K01490 AMPD; AMP deaminase [EC:3.5.4.6]
K01490 AMPD; AMP deaminase [EC:3.5.4.6]
K01490 AMPD; AMP deaminase [EC:3.5.4.6]
K00856 E2.7.1.20; adenosine kinase [EC:2.7.1.20]
K00893 DCK; deoxycitidine kinase [EC:2.7.1.74]
K01488 add; adenosine deaminase [EC:3.5.4.4]
K19572 CECR1; adenosine deaminase CECR1 [EC:3.5.4.4]
K00939 adk; adenylate kinase [EC:2.7.4.3]
K00939 adk; adenylate kinase [EC:2.7.4.3]
K00939 adk; adenylate kinase [EC:2.7.4.3]
K00939 adk; adenylate kinase [EC:2.7.4.3]
K00939 adk; adenylate kinase [EC:2.7.4.3]
K00939 adk; adenylate kinase [EC:2.7.4.3]
K00939 adk; adenylate kinase [EC:2.7.4.3]
K18532 AK6; adenylate kinase [EC:2.7.4.3]
K00944 AK3; nucleoside-triphosphate--adenylate kinase [EC:2.7.4.10]
K01509 ENTPD2; adenosinetriphosphatase [EC:3.6.1.-]
K06928 NTPCR; nucleoside-triphosphatase [EC:3.6.1.15]
K13293 PDE4; cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
K13293 PDE4; cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
K13293 PDE4; cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
K13293 PDE4; cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
K18436 PDE7; high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7 [EC:3.1.4.53]
K18436 PDE7; high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7 [EC:3.1.4.53]
K18437 PDE8; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:3.1.4.53]
K18437 PDE8; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:3.1.4.53]
K01522 FHIT; bis(5'-adenosyl)-triphosphatase [EC:3.6.1.29]
K18424 ENPP4; ectonucleotide pyrophosphatase/phosphodiesterase family member 4 [EC:3.6.1.29]
K13811 PAPSS; 3'-phosphoadenosine 5'-phosphosulfate synthase [EC:2.7.7.4 2.7.1.25]
K13811 PAPSS; 3'-phosphoadenosine 5'-phosphosulfate synthase [EC:2.7.7.4 2.7.1.25]
K01513 ENPP1_3; ectonucleotide pyrophosphatase/phosphodiesterase family member 1/3 [EC:3.1.4.1 3.6.1.9]
K01513 ENPP1_3; ectonucleotide pyrophosphatase/phosphodiesterase family member 1/3 [EC:3.1.4.1 3.6.1.9]
K13485 PRHOXNB; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [EC:4.1.1.97]
K01477 alc; allantoicase [EC:3.5.3.4]
     00240 Pyrimidine metabolism [PATH:hsa00240]
 
   09105 Amino acid metabolism
 
   09106 Metabolism of other amino acids
 
   09107 Glycan biosynthesis and metabolism
 
   09108 Metabolism of cofactors and vitamins
 
   09109 Metabolism of terpenoids and polyketides
 
   09110 Biosynthesis of other secondary metabolites
 
   09111 Xenobiotics biodegradation and metabolism
 
   09112 Not included in regular maps
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
 09140 Cellular Processes
 
 09150 Organismal Systems
 
 09160 Human Diseases
 
   09161 Cancer: overview
 
   09162 Cancer: specific types
     05210 Colorectal cancer [PATH:hsa05210]
     05212 Pancreatic cancer [PATH:hsa05212]
     05225 Hepatocellular carcinoma [PATH:hsa05225]
     05226 Gastric cancer [PATH:hsa05226]
     05214 Glioma [PATH:hsa05214]
     05216 Thyroid cancer [PATH:hsa05216]
     05221 Acute myeloid leukemia [PATH:hsa05221]
     05220 Chronic myeloid leukemia [PATH:hsa05220]
     05217 Basal cell carcinoma [PATH:hsa05217]
     05218 Melanoma [PATH:hsa05218]
     05211 Renal cell carcinoma [PATH:hsa05211]
     05219 Bladder cancer [PATH:hsa05219]
     05215 Prostate cancer [PATH:hsa05215]
     05213 Endometrial cancer [PATH:hsa05213]
     05224 Breast cancer [PATH:hsa05224]
     05222 Small cell lung cancer [PATH:hsa05222]
       2272 FHIT; fragile histidine triad diadenosine triphosphatase
       5915 RARB; retinoic acid receptor beta
       6256 RXRA; retinoid X receptor alpha
       6257 RXRB; retinoid X receptor beta
       6258 RXRG; retinoid X receptor gamma
       7157 TP53; tumor protein p53
       1026 CDKN1A; cyclin dependent kinase inhibitor 1A
       1647 GADD45A; growth arrest and DNA damage inducible alpha
       4616 GADD45B; growth arrest and DNA damage inducible beta
       10912 GADD45G; growth arrest and DNA damage inducible gamma
       581 BAX; BCL2 associated X, apoptosis regulator
       578 BAK1; BCL2 antagonist/killer 1
       1643 DDB2; damage specific DNA binding protein 2
       51426 POLK; DNA polymerase kappa
       596 BCL2; BCL2 apoptosis regulator
       54205 CYCS; cytochrome c, somatic
       317 APAF1; apoptotic peptidase activating factor 1
       842 CASP9; caspase 9
       836 CASP3; caspase 3
       4609 MYC; MYC proto-oncogene, bHLH transcription factor
       4149 MAX; MYC associated factor X
       7709 ZBTB17; zinc finger and BTB domain containing 17
       1030 CDKN2B; cyclin dependent kinase inhibitor 2B
       1019 CDK4; cyclin dependent kinase 4
       1021 CDK6; cyclin dependent kinase 6
       595 CCND1; cyclin D1
       1163 CKS1B; CDC28 protein kinase regulatory subunit 1B
       1164 CKS2; CDC28 protein kinase regulatory subunit 2
       6502 SKP2; S-phase kinase associated protein 2
       1027 CDKN1B; cyclin dependent kinase inhibitor 1B
       1017 CDK2; cyclin dependent kinase 2
       898 CCNE1; cyclin E1
       9134 CCNE2; cyclin E2
       5925 RB1; RB transcriptional corepressor 1
       1869 E2F1; E2F transcription factor 1
       1870 E2F2; E2F transcription factor 2
       1871 E2F3; E2F transcription factor 3
       1284 COL4A2; collagen type IV alpha 2 chain
       1286 COL4A4; collagen type IV alpha 4 chain
       1288 COL4A6; collagen type IV alpha 6 chain
       1282 COL4A1; collagen type IV alpha 1 chain
       1287 COL4A5; collagen type IV alpha 5 chain
       1285 COL4A3; collagen type IV alpha 3 chain
       284217 LAMA1; laminin subunit alpha 1
       3908 LAMA2; laminin subunit alpha 2
       3909 LAMA3; laminin subunit alpha 3
       3911 LAMA5; laminin subunit alpha 5
       3910 LAMA4; laminin subunit alpha 4
       3912 LAMB1; laminin subunit beta 1
       3913 LAMB2; laminin subunit beta 2
       3914 LAMB3; laminin subunit beta 3
       22798 LAMB4; laminin subunit beta 4
       3915 LAMC1; laminin subunit gamma 1
       3918 LAMC2; laminin subunit gamma 2
       10319 LAMC3; laminin subunit gamma 3
       2335 FN1; fibronectin 1
       3673 ITGA2; integrin subunit alpha 2
       3674 ITGA2B; integrin subunit alpha 2b
       3675 ITGA3; integrin subunit alpha 3
       3655 ITGA6; integrin subunit alpha 6
       3685 ITGAV; integrin subunit alpha V
       3688 ITGB1; integrin subunit beta 1
       5747 PTK2; protein tyrosine kinase 2
       5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
       5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
       8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
       5728 PTEN; phosphatase and tensin homolog
       207 AKT1; AKT serine/threonine kinase 1
       208 AKT2; AKT serine/threonine kinase 2
       10000 AKT3; AKT serine/threonine kinase 3
       1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
       3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
       8517 IKBKG; inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
       4792 NFKBIA; NFKB inhibitor alpha
       4790 NFKB1; nuclear factor kappa B subunit 1
       5970 RELA; RELA proto-oncogene, NF-kB subunit
       329 BIRC2; baculoviral IAP repeat containing 2
       330 BIRC3; baculoviral IAP repeat containing 3
       331 XIAP; X-linked inhibitor of apoptosis
       79444 BIRC7; baculoviral IAP repeat containing 7
       598 BCL2L1; BCL2 like 1
       7185 TRAF1; TNF receptor associated factor 1
       7186 TRAF2; TNF receptor associated factor 2
       7187 TRAF3; TNF receptor associated factor 3
       9618 TRAF4; TNF receptor associated factor 4
       7188 TRAF5; TNF receptor associated factor 5
       7189 TRAF6; TNF receptor associated factor 6
       5743 PTGS2; prostaglandin-endoperoxide synthase 2
       4843 NOS2; nitric oxide synthase 2
K01522 FHIT; bis(5'-adenosyl)-triphosphatase [EC:3.6.1.29]
K08528 RARB; retinoic acid receptor beta
K08524 RXRA; retinoid X receptor alpha
K08525 RXRB; retinoid X receptor beta
K08526 RXRG; retinoid X receptor gamma
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K02161 BCL2; apoptosis regulator Bcl-2
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04377 MYC; Myc proto-oncogene protein
K04453 MAX; Max protein
K10500 ZBTB17; zinc finger and BTB domain-containing protein 17
K04685 CDKN2B; cyclin-dependent kinase inhibitor 2B
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K04503 CCND1; G1/S-specific cyclin-D1
K02219 CKS1; cyclin-dependent kinase regulatory subunit CKS1
K02219 CKS1; cyclin-dependent kinase regulatory subunit CKS1
K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K05637 LAMA1_2; laminin, alpha 1/2
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K05717 FN1; fibronectin 1
K06481 ITGA2; integrin alpha 2
K06476 ITGA2B; integrin alpha 2B
K06482 ITGA3; integrin alpha 3
K06485 ITGA6; integrin alpha 6
K06487 ITGAV; integrin alpha V
K05719 ITGB1; integrin beta 1
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K03172 TRAF1; TNF receptor-associated factor 1
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K03174 TRAF3; TNF receptor-associated factor 3
K09848 TRAF4; TNF receptor-associated factor 4
K09849 TRAF5; TNF receptor-associated factor 5
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
     05223 Non-small cell lung cancer [PATH:hsa05223]
       2272 FHIT; fragile histidine triad diadenosine triphosphatase
       5915 RARB; retinoic acid receptor beta
       6256 RXRA; retinoid X receptor alpha
       6257 RXRB; retinoid X receptor beta
       6258 RXRG; retinoid X receptor gamma
       1029 CDKN2A; cyclin dependent kinase inhibitor 2A
       1019 CDK4; cyclin dependent kinase 4
       1021 CDK6; cyclin dependent kinase 6
       595 CCND1; cyclin D1
       5925 RB1; RB transcriptional corepressor 1
       1869 E2F1; E2F transcription factor 1
       1870 E2F2; E2F transcription factor 2
       1871 E2F3; E2F transcription factor 3
       3845 KRAS; KRAS proto-oncogene, GTPase
       11186 RASSF1; Ras association domain family member 1
       83593 RASSF5; Ras association domain family member 5
       6789 STK4; serine/threonine kinase 4
       5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
       5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
       8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
       5170 PDPK1; 3-phosphoinositide dependent protein kinase 1
       207 AKT1; AKT serine/threonine kinase 1
       208 AKT2; AKT serine/threonine kinase 2
       10000 AKT3; AKT serine/threonine kinase 3
       572 BAD; BCL2 associated agonist of cell death
       842 CASP9; caspase 9
       2309 FOXO3; forkhead box O3
       1950 EGF; epidermal growth factor
       7039 TGFA; transforming growth factor alpha
       1956 EGFR; epidermal growth factor receptor
       2064 ERBB2; erb-b2 receptor tyrosine kinase 2
       3082 HGF; hepatocyte growth factor
       4233 MET; MET proto-oncogene, receptor tyrosine kinase
       2885 GRB2; growth factor receptor bound protein 2
       6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
       6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
       3265 HRAS; HRas proto-oncogene, GTPase
       4893 NRAS; NRAS proto-oncogene, GTPase
       369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
       673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
       5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
       5604 MAP2K1; mitogen-activated protein kinase kinase 1
       5605 MAP2K2; mitogen-activated protein kinase kinase 2
       5594 MAPK1; mitogen-activated protein kinase 1
       5595 MAPK3; mitogen-activated protein kinase 3
       5335 PLCG1; phospholipase C gamma 1
       5336 PLCG2; phospholipase C gamma 2
       5578 PRKCA; protein kinase C alpha
       5579 PRKCB; protein kinase C beta
       5582 PRKCG; protein kinase C gamma
       7157 TP53; tumor protein p53
       1026 CDKN1A; cyclin dependent kinase inhibitor 1A
       1647 GADD45A; growth arrest and DNA damage inducible alpha
       4616 GADD45B; growth arrest and DNA damage inducible beta
       10912 GADD45G; growth arrest and DNA damage inducible gamma
       581 BAX; BCL2 associated X, apoptosis regulator
       578 BAK1; BCL2 antagonist/killer 1
       1643 DDB2; damage specific DNA binding protein 2
       51426 POLK; DNA polymerase kappa
       3798 KIF5A; kinesin family member 5A
       3799 KIF5B; kinesin family member 5B
       3800 KIF5C; kinesin family member 5C
       5979 RET; ret proto-oncogene
       27436 EML4; EMAP like 4
       238 ALK; ALK receptor tyrosine kinase
       3718 JAK3; Janus kinase 3
       6774 STAT3; signal transducer and activator of transcription 3
       6776 STAT5A; signal transducer and activator of transcription 5A
       6777 STAT5B; signal transducer and activator of transcription 5B
K01522 FHIT; bis(5'-adenosyl)-triphosphatase [EC:3.6.1.29]
K08528 RARB; retinoic acid receptor beta
K08524 RXRA; retinoid X receptor alpha
K08525 RXRB; retinoid X receptor beta
K08526 RXRG; retinoid X receptor gamma
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K04503 CCND1; G1/S-specific cyclin-D1
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K07827 KRAS; GTPase KRas
K09850 RASSF1; Ras association domain-containing protein 1
K08015 RASSF5; Ras association domain-containing protein 5
K04411 STK4; serine/threonine kinase 4
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K09408 FOXO3; forkhead box protein O3
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05460 HGF; hepatocyte growth factor
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K10396 KIF5; kinesin family member 5
K10396 KIF5; kinesin family member 5
K10396 KIF5; kinesin family member 5
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K15420 EML4; echinoderm microtubule-associated protein-like 4
K05119 ALK; anaplastic lymphoma kinase [EC:2.7.10.1]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
 
   09163 Immune disease
 
   09164 Neurodegenerative disease
 
   09165 Substance dependence
 
   09166 Cardiovascular disease
 
   09167 Endocrine and metabolic disease
 
   09171 Infectious disease: bacterial
 
   09172 Infectious disease: viral
 
   09174 Infectious disease: parasitic
 
   09175 Drug resistance: antimicrobial
 
   09176 Drug resistance: antineoplastic
 
 09180 Brite Hierarchies
 
 09190 Not Included in Pathway or Brite

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: January 21, 2021