KEGG Orthology (KO) - Homo sapiens (human)

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     KO
 09100 Metabolism
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
   09131 Membrane transport
 
   09132 Signal transduction
     02020 Two-component system
     04010 MAPK signaling pathway [PATH:hsa04010]
     04013 MAPK signaling pathway - fly
     04016 MAPK signaling pathway - plant
     04011 MAPK signaling pathway - yeast
     04012 ErbB signaling pathway [PATH:hsa04012]
     04014 Ras signaling pathway [PATH:hsa04014]
     04015 Rap1 signaling pathway [PATH:hsa04015]
     04310 Wnt signaling pathway [PATH:hsa04310]
       64840 PORCN; porcupine O-acyltransferase
       7471 WNT1; Wnt family member 1
       7472 WNT2; Wnt family member 2
       7482 WNT2B; Wnt family member 2B
       7473 WNT3; Wnt family member 3
       89780 WNT3A; Wnt family member 3A
       54361 WNT4; Wnt family member 4
       7474 WNT5A; Wnt family member 5A
       81029 WNT5B; Wnt family member 5B
       7475 WNT6; Wnt family member 6
       7476 WNT7A; Wnt family member 7A
       7477 WNT7B; Wnt family member 7B
       7478 WNT8A; Wnt family member 8A
       7479 WNT8B; Wnt family member 8B
       7483 WNT9A; Wnt family member 9A
       7484 WNT9B; Wnt family member 9B
       7480 WNT10B; Wnt family member 10B
       80326 WNT10A; Wnt family member 10A
       7481 WNT11; Wnt family member 11
       51384 WNT16; Wnt family member 16
       9350 CER1; cerberus 1, DAN family BMP antagonist
       147111 NOTUM; notum, palmitoleoyl-protein carboxylesterase
       11197 WIF1; WNT inhibitory factor 1
       50964 SOST; sclerostin
       22943 DKK1; dickkopf WNT signaling pathway inhibitor 1
       27123 DKK2; dickkopf WNT signaling pathway inhibitor 2
       27121 DKK4; dickkopf WNT signaling pathway inhibitor 4
       5176 SERPINF1; serpin family F member 1
       6422 SFRP1; secreted frizzled related protein 1
       6423 SFRP2; secreted frizzled related protein 2
       2487 FRZB; frizzled related protein
       6424 SFRP4; secreted frizzled related protein 4
       6425 SFRP5; secreted frizzled related protein 5
       284654 RSPO1; R-spondin 1
       340419 RSPO2; R-spondin 2
       84870 RSPO3; R-spondin 3
       343637 RSPO4; R-spondin 4
       55366 LGR4; leucine rich repeat containing G protein-coupled receptor 4
       8549 LGR5; leucine rich repeat containing G protein-coupled receptor 5
       59352 LGR6; leucine rich repeat containing G protein-coupled receptor 6
       54894 RNF43; ring finger protein 43
       84133 ZNRF3; zinc and ring finger 3
       8321 FZD1; frizzled class receptor 1
       8324 FZD7; frizzled class receptor 7
       2535 FZD2; frizzled class receptor 2
       7976 FZD3; frizzled class receptor 3
       8322 FZD4; frizzled class receptor 4
       7855 FZD5; frizzled class receptor 5
       8325 FZD8; frizzled class receptor 8
       8323 FZD6; frizzled class receptor 6
       11211 FZD10; frizzled class receptor 10
       8326 FZD9; frizzled class receptor 9
       4041 LRP5; LDL receptor related protein 5
       4040 LRP6; LDL receptor related protein 6
       25805 BAMBI; BMP and activin membrane bound inhibitor
       147495 APCDD1; APC down-regulated 1
       164284 APCDD1L; APC down-regulated 1 like
       1454 CSNK1E; casein kinase 1 epsilon
       102800317 TPTEP2-CSNK1E; TPTEP2-CSNK1E readthrough
       440193 CCDC88C; coiled-coil domain containing 88C
       1857 DVL3; dishevelled segment polarity protein 3
       1856 DVL2; dishevelled segment polarity protein 2
       1855 DVL1; dishevelled segment polarity protein 1
       10023 FRAT1; FRAT regulator of WNT signaling pathway 1
       23401 FRAT2; FRAT regulator of WNT signaling pathway 2
       1457 CSNK2A1; casein kinase 2 alpha 1
       1459 CSNK2A2; casein kinase 2 alpha 2
       283106 CSNK2A3; casein kinase 2 alpha 3
       1460 CSNK2B; casein kinase 2 beta
       85407 NKD1; NKD inhibitor of WNT signaling pathway 1
       85409 NKD2; NKD inhibitor of WNT signaling pathway 2
       80319 CXXC4; CXXC finger protein 4
       59343 SENP2; SUMO specific peptidase 2
       2932 GSK3B; glycogen synthase kinase 3 beta
       1499 CTNNB1; catenin beta 1
       8312 AXIN1; axin 1
       8313 AXIN2; axin 2
       324 APC; APC regulator of WNT signaling pathway
       10297 APC2; APC regulator of WNT signaling pathway 2
       122011 CSNK1A1L; casein kinase 1 alpha 1 like
       1452 CSNK1A1; casein kinase 1 alpha 1
       6932 TCF7; transcription factor 7
       83439 TCF7L1; transcription factor 7 like 1
       6934 TCF7L2; transcription factor 7 like 2
       51176 LEF1; lymphoid enhancer binding factor 1
       84445 LZTS2; leucine zipper tumor suppressor 2
       56998 CTNNBIP1; catenin beta interacting protein 1
       25776 CBY1; chibby 1, beta catenin antagonist
       57680 CHD8; chromodomain helicase DNA binding protein 8
       4163 MCC; MCC regulator of WNT signaling pathway
       57805 CCAR2; cell cycle and apoptosis regulator 2
       23411 SIRT1; sirtuin 1
       64321 SOX17; SRY-box transcription factor 17
       1487 CTBP1; C-terminal binding protein 1
       1488 CTBP2; C-terminal binding protein 2
       102723796 TLE7; TLE family member 7
       7088 TLE1; TLE family member 1, transcriptional corepressor
       7089 TLE2; TLE family member 2, transcriptional corepressor
       7090 TLE3; TLE family member 3, transcriptional corepressor
       7091 TLE4; TLE family member 4, transcriptional corepressor
       79816 TLE6; TLE family member 6, subcortical maternal complex member
       1501 CTNND2; catenin delta 2
       1387 CREBBP; CREB binding protein
       2033 EP300; E1A binding protein p300
       8607 RUVBL1; RuvB like AAA ATPase 1
       4089 SMAD4; SMAD family member 4
       4088 SMAD3; SMAD family member 3
       6885 MAP3K7; mitogen-activated protein kinase kinase kinase 7
       51701 NLK; nemo like kinase
       4609 MYC; MYC proto-oncogene, bHLH transcription factor
       3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
       8061 FOSL1; FOS like 1, AP-1 transcription factor subunit
       595 CCND1; cyclin D1
       894 CCND2; cyclin D2
       896 CCND3; cyclin D3
       8840 CCN4; cellular communication network factor 4
       5467 PPARD; peroxisome proliferator activated receptor delta
       4316 MMP7; matrix metallopeptidase 7
       5663 PSEN1; presenilin 1
       5566 PRKACA; protein kinase cAMP-activated catalytic subunit alpha
       5567 PRKACB; protein kinase cAMP-activated catalytic subunit beta
       5568 PRKACG; protein kinase cAMP-activated catalytic subunit gamma
       7157 TP53; tumor protein p53
       6477 SIAH1; siah E3 ubiquitin protein ligase 1
       27101 CACYBP; calcyclin binding protein
       6500 SKP1; S-phase kinase associated protein 1
       6907 TBL1X; transducin beta like 1 X-linked
       90665 TBL1Y; transducin beta like 1 Y-linked
       79718 TBL1XR1; TBL1X/Y related 1
       8945 BTRC; beta-transducin repeat containing E3 ubiquitin protein ligase
       23291 FBXW11; F-box and WD repeat domain containing 11
       8454 CUL1; cullin 1
       9978 RBX1; ring-box 1
       2239 GPC4; glypican 4
       4919 ROR1; receptor tyrosine kinase like orphan receptor 1
       4920 ROR2; receptor tyrosine kinase like orphan receptor 2
       6259 RYK; receptor like tyrosine kinase
       57216 VANGL2; VANGL planar cell polarity protein 2
       81839 VANGL1; VANGL planar cell polarity protein 1
       144165 PRICKLE1; prickle planar cell polarity protein 1
       166336 PRICKLE2; prickle planar cell polarity protein 2
       29964 PRICKLE4; prickle planar cell polarity protein 4
       4007 PRICKLE3; prickle planar cell polarity protein 3
       27130 INVS; inversin
       23002 DAAM1; dishevelled associated activator of morphogenesis 1
       23500 DAAM2; dishevelled associated activator of morphogenesis 2
       387 RHOA; ras homolog family member A
       9475 ROCK2; Rho associated coiled-coil containing protein kinase 2
       5879 RAC1; Rac family small GTPase 1
       5880 RAC2; Rac family small GTPase 2
       5881 RAC3; Rac family small GTPase 3
       5599 MAPK8; mitogen-activated protein kinase 8
       5602 MAPK10; mitogen-activated protein kinase 10
       5601 MAPK9; mitogen-activated protein kinase 9
       23236 PLCB1; phospholipase C beta 1
       5330 PLCB2; phospholipase C beta 2
       5331 PLCB3; phospholipase C beta 3
       5332 PLCB4; phospholipase C beta 4
       815 CAMK2A; calcium/calmodulin dependent protein kinase II alpha
       817 CAMK2D; calcium/calmodulin dependent protein kinase II delta
       816 CAMK2B; calcium/calmodulin dependent protein kinase II beta
       818 CAMK2G; calcium/calmodulin dependent protein kinase II gamma
       5530 PPP3CA; protein phosphatase 3 catalytic subunit alpha
       5532 PPP3CB; protein phosphatase 3 catalytic subunit beta
       5533 PPP3CC; protein phosphatase 3 catalytic subunit gamma
       5534 PPP3R1; protein phosphatase 3 regulatory subunit B, alpha
       5535 PPP3R2; protein phosphatase 3 regulatory subunit B, beta
       5578 PRKCA; protein kinase C alpha
       5579 PRKCB; protein kinase C beta
       5582 PRKCG; protein kinase C gamma
       4772 NFATC1; nuclear factor of activated T cells 1
       4773 NFATC2; nuclear factor of activated T cells 2
       4775 NFATC3; nuclear factor of activated T cells 3
       4776 NFATC4; nuclear factor of activated T cells 4
K00181 PORCN; O-palmitoleoyl transferase [EC:2.3.1.250]
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K01645 CER1; cerberus 1
K19882 NOTUM; O-palmitoleoyl-L-serine hydrolase [EC:3.1.1.98]
K01691 WIF1; WNT inhibitory factor 1
K16834 SOST; sclerostin
K02165 DKK1_2_4; dickkopf 1/2/4
K02165 DKK1_2_4; dickkopf 1/2/4
K02165 DKK1_2_4; dickkopf 1/2/4
K19614 SERPINF1; pigment epithelium-derived factor
K02166 SFRP1; secreted frizzled-related protein 1
K02176 SFRP2; secreted frizzled-related protein 2
K25481 FRZB; secreted frizzled-related protein 3
K02185 SFRP4; secreted frizzled-related protein 4
K02222 SFRP5; secreted frizzled-related protein 5
K19471 RSPO1; R-spondin 1
K23097 RSPO2; R-spondin 2
K23098 RSPO3; R-spondin 3
K23099 RSPO4; R-spondin 4
K04309 LGR4; leucine-rich repeat-containing G protein-coupled receptor 4
K04308 LGR5; leucine-rich repeat-containing G protein-coupled receptor 5
K08399 LGR6; leucine-rich repeat-containing G protein-coupled receptor 6
K15694 RNF43; E3 ubiquitin-protein ligase RNF43 [EC:2.3.2.27]
K16273 ZNRF3; E3 ubiquitin-protein ligase ZNRF3 [EC:2.3.2.27]
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K02842 FZD9_10; frizzled 9/10
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K10162 BAMBI; BMP and activin membrane-bound inhibitor
K25812 APCDD1; protein APCDD1
K25812 APCDD1; protein APCDD1
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
K25811 CCDC88C; protein Daple
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03096 FRAT2; frequently rearranged in advanced T-cell lymphomas 2
K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
K03115 CSNK2B; casein kinase II subunit beta
K03213 NKD; naked cuticle
K03213 NKD; naked cuticle
K03344 IDAX; Dvl-binding protein IDAX
K03345 SENP2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02105 CTNNB1; catenin beta 1
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K26471 LZTS2; leucine zipper putative tumor suppressor 2
K04493 ICAT; beta-catenin-interacting protein 1 (inhibitor of beta-catenin and Tcf-4)
K23402 CBY1; protein chibby 1
K04494 CHD8; chromodomain helicase DNA binding protein 8 [EC:5.6.2.-]
K26734 MCC; colorectal mutant cancer protein
K25816 CCAR2; cell cycle and apoptosis regulator protein 2
K11411 SIRT1; NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K04495 SOX17; transcription factor SOX17 (SOX group F)
K04496 CTBP; C-terminal binding protein [EC:1.1.1.428]
K04496 CTBP; C-terminal binding protein [EC:1.1.1.428]
K04497 GRO; groucho
K04497 GRO; groucho
K04497 GRO; groucho
K04497 GRO; groucho
K04497 GRO; groucho
K04497 GRO; groucho
K23491 CTNND2; catenin delta-2
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04499 RUVBL1; RuvB-like protein 1 [EC:5.6.2.4]
K04501 SMAD4; mothers against decapentaplegic homolog 4
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04468 NLK; nemo like kinase [EC:2.7.11.24]
K04377 MYC; Myc proto-oncogene protein
K04448 JUN; transcription factor AP-1
K04502 FOSL1; fos-like antigen 1
K04503 CCND1; G1/S-specific cyclin-D1
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K22471 CCN4; CCN family member 4
K04504 NR1C2; peroxisome proliferator-activated receptor delta
K01397 MMP7; matrix metalloproteinase-7 (matrilysin, uterine) [EC:3.4.24.23]
K04505 PSEN1; presenilin 1 [EC:3.4.23.-]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04451 TP53; tumor protein p53
K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
K04507 CACYBP; calcyclin binding protein
K03094 SKP1; S-phase kinase-associated protein 1
K04508 TBL1; transducin (beta)-like 1
K04508 TBL1; transducin (beta)-like 1
K04508 TBL1; transducin (beta)-like 1
K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
K03347 CUL1; cullin 1
K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K08110 GPC4; glypican 4
K05122 ROR1; receptor tyrosine kinase-like orphan receptor 1 [EC:2.7.10.1]
K05123 ROR2; receptor tyrosine kinase-like orphan receptor 2 [EC:2.7.10.1]
K05128 RYK; RYK receptor-like tyrosine kinase [EC:2.7.10.1]
K04510 VANGL; vang-like
K04510 VANGL; vang-like
K04511 PRICKLE; prickle
K04511 PRICKLE; prickle
K04511 PRICKLE; prickle
K04511 PRICKLE; prickle
K19626 INVS; inversin
K04512 DAAM; dishevelled associated activator of morphogenesis
K04512 DAAM; dishevelled associated activator of morphogenesis
K04513 RHOA; Ras homolog gene family, member A
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K04348 PPP3C; serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K06268 PPP3R; serine/threonine-protein phosphatase 2B regulatory subunit
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04446 NFATC1; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3; nuclear factor of activated T-cells, cytoplasmic 3
K17334 NFATC4; nuclear factor of activated T-cells, cytoplasmic 4
     04330 Notch signaling pathway [PATH:hsa04330]
     04340 Hedgehog signaling pathway [PATH:hsa04340]
     04341 Hedgehog signaling pathway - fly
     04350 TGF-beta signaling pathway [PATH:hsa04350]
     04390 Hippo signaling pathway [PATH:hsa04390]
     04391 Hippo signaling pathway - fly
     04392 Hippo signaling pathway - multiple species [PATH:hsa04392]
     04370 VEGF signaling pathway [PATH:hsa04370]
     04371 Apelin signaling pathway [PATH:hsa04371]
     04630 JAK-STAT signaling pathway [PATH:hsa04630]
     04064 NF-kappa B signaling pathway [PATH:hsa04064]
     04668 TNF signaling pathway [PATH:hsa04668]
     04066 HIF-1 signaling pathway [PATH:hsa04066]
     04068 FoxO signaling pathway [PATH:hsa04068]
     04020 Calcium signaling pathway [PATH:hsa04020]
     04070 Phosphatidylinositol signaling system [PATH:hsa04070]
     04072 Phospholipase D signaling pathway [PATH:hsa04072]
     04071 Sphingolipid signaling pathway [PATH:hsa04071]
     04024 cAMP signaling pathway [PATH:hsa04024]
     04022 cGMP-PKG signaling pathway [PATH:hsa04022]
     04151 PI3K-Akt signaling pathway [PATH:hsa04151]
     04152 AMPK signaling pathway [PATH:hsa04152]
     04150 mTOR signaling pathway [PATH:hsa04150]
     04075 Plant hormone signal transduction
 
   09133 Signaling molecules and interaction
 
 09140 Cellular Processes
 
 09150 Organismal Systems
 
 09160 Human Diseases
 
 09180 Brite Hierarchies
 
 09190 Not Included in Pathway or Brite

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: April 23, 2024