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 09100 Metabolism
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09120 Genetic Information Processing
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09130 Environmental Information Processing
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09140 Cellular Processes
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 09150 Organismal Systems
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09151 Immune system
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04640 Hematopoietic cell lineage [PATH:hsa04640]
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04610 Complement and coagulation cascades [PATH:hsa04610]
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04611 Platelet activation [PATH:hsa04611]
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04613 Neutrophil extracellular trap formation [PATH:hsa04613]
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04620 Toll-like receptor signaling pathway [PATH:hsa04620]
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 04624 Toll and Imd signaling pathway
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04621 NOD-like receptor signaling pathway [PATH:hsa04621]
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10392 NOD1; nucleotide binding oligomerization domain containing 1
8767 RIPK2; receptor interacting serine/threonine kinase 2
8517 IKBKG; inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
4793 NFKBIB; NFKB inhibitor beta
4792 NFKBIA; NFKB inhibitor alpha
4790 NFKB1; nuclear factor kappa B subunit 1
5970 RELA; RELA proto-oncogene, NF-kB subunit
3553 IL1B; interleukin 1 beta
3606 IL18; interleukin 18
3569 IL6; interleukin 6
7124 TNF; tumor necrosis factor
3576 CXCL8; C-X-C motif chemokine ligand 8
2919 CXCL1; C-X-C motif chemokine ligand 1
2920 CXCL2; C-X-C motif chemokine ligand 2
2921 CXCL3; C-X-C motif chemokine ligand 3
6347 CCL2; C-C motif chemokine ligand 2
6352 CCL5; C-C motif chemokine ligand 5
820 CAMP; cathelicidin antimicrobial peptide
1667 DEFA1; defensin alpha 1
1668 DEFA3; defensin alpha 3
1669 DEFA4; defensin alpha 4
1670 DEFA5; defensin alpha 5
1671 DEFA6; defensin alpha 6
728358 DEFA1B; defensin alpha 1B
1673 DEFB4A; defensin beta 4A
100289462 DEFB4B; defensin beta 4B
414325 DEFB103A; defensin beta 103A
55894 DEFB103B; defensin beta 103B
64127 NOD2; nucleotide binding oligomerization domain containing 2
6885 MAP3K7; mitogen-activated protein kinase kinase kinase 7
10454 TAB1; TGF-beta activated kinase 1 (MAP3K7) binding protein 1
23118 TAB2; TGF-beta activated kinase 1 (MAP3K7) binding protein 2
257397 TAB3; TGF-beta activated kinase 1 (MAP3K7) binding protein 3
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
5599 MAPK8; mitogen-activated protein kinase 8
5602 MAPK10; mitogen-activated protein kinase 10
5601 MAPK9; mitogen-activated protein kinase 9
5600 MAPK11; mitogen-activated protein kinase 11
6300 MAPK12; mitogen-activated protein kinase 12
5603 MAPK13; mitogen-activated protein kinase 13
1432 MAPK14; mitogen-activated protein kinase 14
3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
55054 ATG16L1; autophagy related 16 like 1
9474 ATG5; autophagy related 5
9140 ATG12; autophagy related 12
11337 GABARAP; GABA type A receptor-associated protein
23710 GABARAPL1; GABA type A receptor associated protein like 1
11345 GABARAPL2; GABA type A receptor associated protein like 2
440738 MAP1LC3C; microtubule associated protein 1 light chain 3 gamma
81631 MAP1LC3B; microtubule associated protein 1 light chain 3 beta
84557 MAP1LC3A; microtubule associated protein 1 light chain 3 alpha
643246 MAP1LC3B2; microtubule associated protein 1 light chain 3 beta 2
10910 SUGT1; SGT1 homolog, MIS12 kinetochore complex assembly cochaperone
81858 SHARPIN; SHANK associated RH domain interactor
10616 RBCK1; RANBP2-type and C3HC4-type zinc finger containing 1
55072 RNF31; ring finger protein 31
331 XIAP; X-linked inhibitor of apoptosis
84674 CARD6; caspase recruitment domain family member 6
7205 TRIP6; thyroid hormone receptor interactor 6
55914 ERBIN; erbb2 interacting protein
329 BIRC2; baculoviral IAP repeat containing 2
330 BIRC3; baculoviral IAP repeat containing 3
7186 TRAF2; TNF receptor associated factor 2
7188 TRAF5; TNF receptor associated factor 5
7189 TRAF6; TNF receptor associated factor 6
64170 CARD9; caspase recruitment domain family member 9
7128 TNFAIP3; TNF alpha induced protein 3
57506 MAVS; mitochondrial antiviral signaling protein
7187 TRAF3; TNF receptor associated factor 3
29110 TBK1; TANK binding kinase 1
9641 IKBKE; inhibitor of nuclear factor kappa B kinase subunit epsilon
10010 TANK; TRAF family member associated NFKB activator
3661 IRF3; interferon regulatory factor 3
3665 IRF7; interferon regulatory factor 7
3439 IFNA1; interferon alpha 1
3440 IFNA2; interferon alpha 2
3441 IFNA4; interferon alpha 4
3442 IFNA5; interferon alpha 5
3443 IFNA6; interferon alpha 6
3444 IFNA7; interferon alpha 7
3445 IFNA8; interferon alpha 8
3446 IFNA10; interferon alpha 10
3447 IFNA13; interferon alpha 13
3448 IFNA14; interferon alpha 14
3449 IFNA16; interferon alpha 16
3451 IFNA17; interferon alpha 17
3452 IFNA21; interferon alpha 21
3456 IFNB1; interferon beta 1
79671 NLRX1; NLR family member X1
118429 ANTXR2; ANTXR cell adhesion molecule 2
84168 ANTXR1; ANTXR cell adhesion molecule 1
22861 NLRP1; NLR family pyrin domain containing 1
29108 PYCARD; PYD and CARD domain containing
834 CASP1; caspase 1
596 BCL2; BCL2 apoptosis regulator
598 BCL2L1; BCL2 like 1
1508 CTSB; cathepsin B
114548 NLRP3; NLR family pyrin domain containing 3
24145 PANX1; pannexin 1
5027 P2RX7; purinergic receptor P2X 7
7226 TRPM2; transient receptor potential cation channel subfamily M member 2
54822 TRPM7; transient receptor potential cation channel subfamily M member 7
51393 TRPV2; transient receptor potential cation channel subfamily V member 2
846 CASR; calcium sensing receptor
222545 GPRC6A; G protein-coupled receptor class C group 6 member A
23236 PLCB1; phospholipase C beta 1
5330 PLCB2; phospholipase C beta 2
5331 PLCB3; phospholipase C beta 3
5332 PLCB4; phospholipase C beta 4
3708 ITPR1; inositol 1,4,5-trisphosphate receptor type 1
3709 ITPR2; inositol 1,4,5-trisphosphate receptor type 2
3710 ITPR3; inositol 1,4,5-trisphosphate receptor type 3
7416 VDAC1; voltage dependent anion channel 1
7417 VDAC2; voltage dependent anion channel 2
7419 VDAC3; voltage dependent anion channel 3
90550 MCU; mitochondrial calcium uniporter
4938 OAS1; 2'-5'-oligoadenylate synthetase 1
4939 OAS2; 2'-5'-oligoadenylate synthetase 2
4940 OAS3; 2'-5'-oligoadenylate synthetase 3
6041 RNASEL; ribonuclease L
56919 DHX33; DEAH-box helicase 33
55669 MFN1; mitofusin 1
9927 MFN2; mitofusin 2
8737 RIPK1; receptor interacting serine/threonine kinase 1
11035 RIPK3; receptor interacting serine/threonine kinase 3
10059 DNM1L; dynamin 1 like
10135 NAMPT; nicotinamide phosphoribosyltransferase
1536 CYBB; cytochrome b-245 beta chain
1535 CYBA; cytochrome b-245 alpha chain
10628 TXNIP; thioredoxin interacting protein
7295 TXN; thioredoxin
25828 TXN2; thioredoxin 2
140609 NEK7; NIMA related kinase 7
79184 BRCC3; BRCA1/BRCA2-containing complex subunit 3
3320 HSP90AA1; heat shock protein 90 alpha family class A member 1
3326 HSP90AB1; heat shock protein 90 alpha family class B member 1
22900 CARD8; caspase recruitment domain family member 8
63940 GPSM3; G protein signaling modulator 3
345611 IRGM; immunity related GTPase M
260434 PYDC1; pyrin domain containing 1
152138 PYDC2; pyrin domain containing 2
4210 MEFV; MEFV innate immunity regulator, pyrin
9051 PSTPIP1; proline-serine-threonine phosphatase interacting protein 1
841 CASP8; caspase 8
8772 FADD; Fas associated via death domain
100506742 CASP12; caspase 12 (gene/pseudogene)
59082 CARD18; caspase recruitment domain family member 18
114769 CARD16; caspase recruitment domain family member 16
171389 NLRP6; NLR family pyrin domain containing 6
199713 NLRP7; NLR family pyrin domain containing 7
91662 NLRP12; NLR family pyrin domain containing 12
4671 NAIP; NLR family apoptosis inhibitory protein
58484 NLRC4; NLR family CARD domain containing 4
5580 PRKCD; protein kinase C delta
2634 GBP2; guanylate binding protein 2
115362 GBP5; guanylate binding protein 5
9447 AIM2; absent in melanoma 2
3428 IFI16; interferon gamma inducible protein 16
7158 TP53BP1; tumor protein p53 binding protein 1
107181291 PYDC5; pyrin domain containing 5
387 RHOA; ras homolog family member A
5585 PKN1; protein kinase N1
5586 PKN2; protein kinase N2
7531 YWHAE; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
2633 GBP1; guanylate binding protein 1
2635 GBP3; guanylate binding protein 3
115361 GBP4; guanylate binding protein 4
388646 GBP7; guanylate binding protein 7
838 CASP5; caspase 5
837 CASP4; caspase 4
79792 GSDMD; gasdermin D
3454 IFNAR1; interferon alpha and beta receptor subunit 1
3455 IFNAR2; interferon alpha and beta receptor subunit 2
3716 JAK1; Janus kinase 1
7297 TYK2; tyrosine kinase 2
6772 STAT1; signal transducer and activator of transcription 1
6773 STAT2; signal transducer and activator of transcription 2
10379 IRF9; interferon regulatory factor 9
7099 TLR4; toll like receptor 4
148022 TICAM1; TIR domain containing adaptor molecule 1
4615 MYD88; MYD88 innate immune signal transduction adaptor
51135 IRAK4; interleukin 1 receptor associated kinase 4
340061 STING1; stimulator of interferon response cGAMP interactor 1
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K08727 NOD1; nucleotide-binding oligomerization domain-containing protein 1
K08846 RIPK2; receptor-interacting serine/threonine-protein kinase 2 [EC:2.7.11.1]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K02581 NFKBIB; NF-kappa-B inhibitor beta
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04519 IL1B; interleukin 1 beta
K05482 IL18; interleukin 18
K05405 IL6; interleukin 6
K03156 TNF; tumor necrosis factor superfamily, member 2
K10030 IL8; interleukin 8
K05505 CXCL1_2_3; C-X-C motif chemokine 1/2/3
K05505 CXCL1_2_3; C-X-C motif chemokine 1/2/3
K05505 CXCL1_2_3; C-X-C motif chemokine 1/2/3
K14624 CCL2; C-C motif chemokine 2
K12499 CCL5; C-C motif chemokine 5
K13916 CAMP; cathelicidin antimicrobial peptide
K05230 DEFA; defensin, alpha
K05230 DEFA; defensin, alpha
K05230 DEFA; defensin, alpha
K05230 DEFA; defensin, alpha
K05230 DEFA; defensin, alpha
K05230 DEFA; defensin, alpha
K21100 DEFB4; beta-defensin 4
K21100 DEFB4; beta-defensin 4
K23126 DEFB103; beta-defensin 103
K23126 DEFB103; beta-defensin 103
K10165 NOD2; nucleotide-binding oligomerization domain-containing protein 2
K04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04403 MAP3K7IP1; TAK1-binding protein 1
K04404 MAP3K7IP2; TAK1-binding protein 2
K12793 MAP3K7IP3; TAK1-binding protein 3
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K17890 ATG16L1; autophagy-related protein 16-1
K08339 ATG5; autophagy-related protein 5
K08336 ATG12; ubiquitin-like protein ATG12
K08341 GABARAP; GABA(A) receptor-associated protein
K08341 GABARAP; GABA(A) receptor-associated protein
K08341 GABARAP; GABA(A) receptor-associated protein
K10435 MAP1LC; microtubule-associated protein 1 light chain
K10435 MAP1LC; microtubule-associated protein 1 light chain
K10435 MAP1LC; microtubule-associated protein 1 light chain
K10435 MAP1LC; microtubule-associated protein 1 light chain
K12795 SUGT1; suppressor of G2 allele of SKP1
K20894 SHARPIN; shank-associated RH domain-interacting protein
K10630 RBCK1; RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.31]
K11974 RNF31; E3 ubiquitin-protein ligase RNF31 [EC:2.3.2.31]
K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K12797 CARD6; caspase recruitment domain-containing protein 6
K12792 TRIP6; thyroid receptor-interacting protein 6
K12796 ERBIN; erbb2-interacting protein
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K09849 TRAF5; TNF receptor-associated factor 5
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K12794 CARD9; caspase recruitment domain-containing protein 9
K11859 TNFAIP3; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12]
K12648 MAVS; mitochondrial antiviral-signaling protein
K03174 TRAF3; TNF receptor-associated factor 3
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K07211 IKBKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K12650 TANK; TRAF family member-associated NF-kappa-B activator
K05411 IRF3; interferon regulatory factor 3
K09447 IRF7; interferon regulatory factor 7
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K12653 NLRX1; NLR family member X1
K20909 ANTXR; anthrax toxin receptor
K20909 ANTXR; anthrax toxin receptor
K12798 NLRP1; NACHT, LRR and PYD domains-containing protein 1
K12799 PYCARD; apoptosis-associated speck-like protein containing a CARD
K01370 CASP1; caspase 1 [EC:3.4.22.36]
K02161 BCL2; apoptosis regulator Bcl-2
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K01363 CTSB; cathepsin B [EC:3.4.22.1]
K12800 NLRP3; NACHT, LRR and PYD domains-containing protein 3
K03443 PANX1; pannexin 1
K05220 P2RX7; P2X purinoceptor 7
K04977 TRPM2; transient receptor potential cation channel subfamily M member 2 [EC:3.6.1.13]
K04982 TRPM7; transient receptor potential cation channel subfamily M member 7 [EC:2.7.11.1]
K04971 TRPV2; transient receptor potential cation channel subfamily V member 2
K04612 CASR; calcium-sensing receptor
K04622 GPRC6A; G protein-coupled receptor family C group 6 member A
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K05862 VDAC1; voltage-dependent anion channel protein 1
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K20858 MCU; calcium uniporter protein, mitochondrial
K14216 OAS; 2'-5'-oligoadenylate synthetase [EC:2.7.7.84]
K14216 OAS; 2'-5'-oligoadenylate synthetase [EC:2.7.7.84]
K14216 OAS; 2'-5'-oligoadenylate synthetase [EC:2.7.7.84]
K01165 RNASEL; ribonuclease L
K17820 DHX33; ATP-dependent RNA helicase DHX33 [EC:3.6.4.13]
K21356 MFN1; mitofusin 1 [EC:3.6.5.-]
K06030 MFN2; mitofusin 2 [EC:3.6.5.-]
K02861 RIPK1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K08847 RIPK3; receptor-interacting serine/threonine-protein kinase 3 [EC:2.7.11.1]
K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
K03462 NAMPT; nicotinamide phosphoribosyltransferase [EC:2.4.2.12]
K21421 NOX2; NADPH oxidase 2 [EC:1.-.-.-]
K08009 CYBA; cytochrome b-245, alpha polypeptide
K20910 TXNIP; thioredoxin-interacting protein
K03671 TXN; thioredoxin
K03671 TXN; thioredoxin
K20876 NEK7; serine/threonine-protein kinase Nek7 [EC:2.7.11.34]
K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
K04079 HSP90A; molecular chaperone HtpG
K04079 HSP90A; molecular chaperone HtpG
K12801 CARD8; caspase recruitment domain-containing protein 8
K15838 GPSM3; G-protein signaling modulator 3
K14139 IRGM; immunity-related GTPase family M protein [EC:3.6.5.-]
K12802 PYDC1; pyrin domain-containing protein 1
K20911 PYDC2; pyrin domain-containing protein 2
K12803 MEFV; pyrin
K12804 PSTPIP1; proline-serine-threonine phosphatase interacting protein 1
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K02373 FADD; FAS-associated death domain protein
K04741 CASP12; caspase 12 [EC:3.4.22.-]
K12806 CARD16_17_18; caspase recruitment domain-containing protein 16/17/18
K12806 CARD16_17_18; caspase recruitment domain-containing protein 16/17/18
K20863 NLRP6; NACHT, LRR and PYD domains-containing protein 6
K20864 NLRP7; NACHT, LRR and PYD domains-containing protein 7
K20865 NLRP12; NACHT, LRR and PYD domains-containing protein 12
K12807 NAIP; baculoviral IAP repeat-containing protein 1
K12805 NLRC4; NLR family CARD domain-containing protein 4
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K20897 GBP2; guanylate-binding protein 2
K20898 GBP5; guanylate-binding protein 5
K12966 AIM2; absent in melanoma 2
K20914 IFI16; gamma-interferon-inducible protein 16
K20915 TP53BP1; tumor suppressor p53-binding protein 1
K20916 POP3; pyrin domain-only protein 3
K04513 RHOA; Ras homolog gene family, member A
K06071 PKN1; serine/threonine-protein kinase N1 [EC:2.7.11.13]
K23691 PKN2; serine/threonine-protein kinase N2 [EC:2.7.11.13]
K06630 YWHAE; 14-3-3 protein epsilon
K20899 GBP1_3_4_7; guanylate-binding protein 1/3/4/7
K20899 GBP1_3_4_7; guanylate-binding protein 1/3/4/7
K20899 GBP1_3_4_7; guanylate-binding protein 1/3/4/7
K20899 GBP1_3_4_7; guanylate-binding protein 1/3/4/7
K04395 CASP5; caspase 5 [EC:3.4.22.58]
K04394 CASP4; caspase 4 [EC:3.4.22.57 3.4.22.64]
K20917 GSDMD; gasdermin-D
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K04693 IRF9; interferon regulatory factor 9
K10160 TLR4; toll-like receptor 4
K05842 TRIF; toll-like receptor adapter molecule 1
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K12654 STING1; stimulator of interferon genes protein
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04622 RIG-I-like receptor signaling pathway [PATH:hsa04622]
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04623 Cytosolic DNA-sensing pathway [PATH:hsa04623]
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04625 C-type lectin receptor signaling pathway [PATH:hsa04625]
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04650 Natural killer cell mediated cytotoxicity [PATH:hsa04650]
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04612 Antigen processing and presentation [PATH:hsa04612]
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04660 T cell receptor signaling pathway [PATH:hsa04660]
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04658 Th1 and Th2 cell differentiation [PATH:hsa04658]
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04659 Th17 cell differentiation [PATH:hsa04659]
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04657 IL-17 signaling pathway [PATH:hsa04657]
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04662 B cell receptor signaling pathway [PATH:hsa04662]
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04664 Fc epsilon RI signaling pathway [PATH:hsa04664]
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04666 Fc gamma R-mediated phagocytosis [PATH:hsa04666]
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04670 Leukocyte transendothelial migration [PATH:hsa04670]
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04672 Intestinal immune network for IgA production [PATH:hsa04672]
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04062 Chemokine signaling pathway [PATH:hsa04062]
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09152 Endocrine system
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09153 Circulatory system
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09154 Digestive system
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09155 Excretory system
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09156 Nervous system
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09157 Sensory system
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09158 Development and regeneration
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09149 Aging
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09159 Environmental adaptation
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09160 Human Diseases
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09161 Cancer: overview
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09162 Cancer: specific types
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09172 Infectious disease: viral
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09171 Infectious disease: bacterial
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09174 Infectious disease: parasitic
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05146 Amoebiasis [PATH:hsa05146]
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05144 Malaria [PATH:hsa05144]
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05145 Toxoplasmosis [PATH:hsa05145]
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3458 IFNG; interferon gamma
3459 IFNGR1; interferon gamma receptor 1
3460 IFNGR2; interferon gamma receptor 2
3716 JAK1; Janus kinase 1
3717 JAK2; Janus kinase 2
6772 STAT1; signal transducer and activator of transcription 1
4261 CIITA; class II major histocompatibility complex transactivator
3108 HLA-DMA; major histocompatibility complex, class II, DM alpha
3109 HLA-DMB; major histocompatibility complex, class II, DM beta
3111 HLA-DOA; major histocompatibility complex, class II, DO alpha
3112 HLA-DOB; major histocompatibility complex, class II, DO beta
3113 HLA-DPA1; major histocompatibility complex, class II, DP alpha 1
3115 HLA-DPB1; major histocompatibility complex, class II, DP beta 1
3117 HLA-DQA1; major histocompatibility complex, class II, DQ alpha 1
3118 HLA-DQA2; major histocompatibility complex, class II, DQ alpha 2
3119 HLA-DQB1; major histocompatibility complex, class II, DQ beta 1
3122 HLA-DRA; major histocompatibility complex, class II, DR alpha
3123 HLA-DRB1; major histocompatibility complex, class II, DR beta 1
3125 HLA-DRB3; major histocompatibility complex, class II, DR beta 3
3126 HLA-DRB4; major histocompatibility complex, class II, DR beta 4
3127 HLA-DRB5; major histocompatibility complex, class II, DR beta 5
345611 IRGM; immunity related GTPase M
4843 NOS2; nitric oxide synthase 2
8651 SOCS1; suppressor of cytokine signaling 1
4615 MYD88; MYD88 innate immune signal transduction adaptor
3654 IRAK1; interleukin 1 receptor associated kinase 1
51135 IRAK4; interleukin 1 receptor associated kinase 4
7189 TRAF6; TNF receptor associated factor 6
6885 MAP3K7; mitogen-activated protein kinase kinase kinase 7
10454 TAB1; TGF-beta activated kinase 1 (MAP3K7) binding protein 1
23118 TAB2; TGF-beta activated kinase 1 (MAP3K7) binding protein 2
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
5599 MAPK8; mitogen-activated protein kinase 8
5602 MAPK10; mitogen-activated protein kinase 10
5601 MAPK9; mitogen-activated protein kinase 9
5606 MAP2K3; mitogen-activated protein kinase kinase 3
5608 MAP2K6; mitogen-activated protein kinase kinase 6
5600 MAPK11; mitogen-activated protein kinase 11
6300 MAPK12; mitogen-activated protein kinase 12
5603 MAPK13; mitogen-activated protein kinase 13
1432 MAPK14; mitogen-activated protein kinase 14
1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
8517 IKBKG; inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
4792 NFKBIA; NFKB inhibitor alpha
4793 NFKBIB; NFKB inhibitor beta
4790 NFKB1; nuclear factor kappa B subunit 1
5970 RELA; RELA proto-oncogene, NF-kB subunit
3592 IL12A; interleukin 12A
3593 IL12B; interleukin 12B
7124 TNF; tumor necrosis factor
596 BCL2; BCL2 apoptosis regulator
598 BCL2L1; BCL2 like 1
329 BIRC2; baculoviral IAP repeat containing 2
330 BIRC3; baculoviral IAP repeat containing 3
331 XIAP; X-linked inhibitor of apoptosis
79444 BIRC7; baculoviral IAP repeat containing 7
23643 LY96; lymphocyte antigen 96
7099 TLR4; toll like receptor 4
3312 HSPA8; heat shock protein family A (Hsp70) member 8
3303 HSPA1A; heat shock protein family A (Hsp70) member 1A
3305 HSPA1L; heat shock protein family A (Hsp70) member 1 like
3304 HSPA1B; heat shock protein family A (Hsp70) member 1B
3310 HSPA6; heat shock protein family A (Hsp70) member 6
7097 TLR2; toll like receptor 2
284217 LAMA1; laminin subunit alpha 1
3908 LAMA2; laminin subunit alpha 2
3909 LAMA3; laminin subunit alpha 3
3911 LAMA5; laminin subunit alpha 5
3910 LAMA4; laminin subunit alpha 4
3912 LAMB1; laminin subunit beta 1
3913 LAMB2; laminin subunit beta 2
3914 LAMB3; laminin subunit beta 3
22798 LAMB4; laminin subunit beta 4
3915 LAMC1; laminin subunit gamma 1
3918 LAMC2; laminin subunit gamma 2
10319 LAMC3; laminin subunit gamma 3
3655 ITGA6; integrin subunit alpha 6
3688 ITGB1; integrin subunit beta 1
3949 LDLR; low density lipoprotein receptor
7132 TNFRSF1A; TNF receptor superfamily member 1A
841 CASP8; caspase 8
836 CASP3; caspase 3
54205 CYCS; cytochrome c, somatic
842 CASP9; caspase 9
2770 GNAI1; G protein subunit alpha i1
2773 GNAI3; G protein subunit alpha i3
2771 GNAI2; G protein subunit alpha i2
2775 GNAO1; G protein subunit alpha o1
5294 PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
23533 PIK3R5; phosphoinositide-3-kinase regulatory subunit 5
146850 PIK3R6; phosphoinositide-3-kinase regulatory subunit 6
5170 PDPK1; 3-phosphoinositide dependent protein kinase 1
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
10000 AKT3; AKT serine/threonine kinase 3
572 BAD; BCL2 associated agonist of cell death
959 CD40LG; CD40 ligand
958 CD40; CD40 molecule
10105 PPIF; peptidylprolyl isomerase F
1234 CCR5; C-C motif chemokine receptor 5
240 ALOX5; arachidonate 5-lipoxygenase
3586 IL10; interleukin 10
3587 IL10RA; interleukin 10 receptor subunit alpha
3588 IL10RB; interleukin 10 receptor subunit beta
7297 TYK2; tyrosine kinase 2
6774 STAT3; signal transducer and activator of transcription 3
7040 TGFB1; transforming growth factor beta 1
7042 TGFB2; transforming growth factor beta 2
7043 TGFB3; transforming growth factor beta 3
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K04687 IFNG; interferon gamma
K05132 IFNGR1; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K08060 CIITA; MHC class II transactivator [EC:2.7.11.1]
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K06752 MHC2; MHC class II antigen
K14139 IRGM; immunity-related GTPase family M protein [EC:3.6.5.-]
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K04694 SOCS1; suppressor of cytokine signaling 1
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04403 MAP3K7IP1; TAK1-binding protein 1
K04404 MAP3K7IP2; TAK1-binding protein 2
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04432 MAP2K3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02581 NFKBIB; NF-kappa-B inhibitor beta
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K03156 TNF; tumor necrosis factor superfamily, member 2
K02161 BCL2; apoptosis regulator Bcl-2
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
K05400 LY96; lymphocyte antigen 96
K10160 TLR4; toll-like receptor 4
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
K10159 TLR2; toll-like receptor 2
K05637 LAMA1_2; laminin, alpha 1/2
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K06485 ITGA6; integrin alpha 6
K05719 ITGB1; integrin beta 1
K12473 LDLR; low-density lipoprotein receptor
K03158 TNFRSF1A; tumor necrosis factor receptor superfamily member 1A
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K08738 CYC; cytochrome c
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04534 GNAO; guanine nucleotide-binding protein G(o) subunit alpha
K21289 PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153]
K21290 PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6
K21290 PIK3R5_6; phosphoinositide-3-kinase regulatory subunit 5/6
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K03161 TNFSF5; tumor necrosis factor ligand superfamily member 5
K03160 TNFRSF5; tumor necrosis factor receptor superfamily member 5
K09565 PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
K04180 CCR5; C-C chemokine receptor type 5
K00461 ALOX5; arachidonate 5-lipoxygenase [EC:1.13.11.34]
K05443 IL10; interleukin 10
K05134 IL10RA; interleukin 10 receptor alpha
K05135 IL10RB; interleukin 10 receptor beta
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
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05140 Leishmaniasis [PATH:hsa05140]
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05142 Chagas disease [PATH:hsa05142]
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05143 African trypanosomiasis [PATH:hsa05143]
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09163 Immune disease
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09164 Neurodegenerative disease
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09165 Substance dependence
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09166 Cardiovascular disease
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09167 Endocrine and metabolic disease
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09175 Drug resistance: antimicrobial
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09176 Drug resistance: antineoplastic
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09180 Brite Hierarchies
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09190 Not Included in Pathway or Brite
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KEGG Orthology (KO) - Homo sapiens (human)