KEGG Orthology (KO) - Homo sapiens (human)

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     KO
 09100 Metabolism
 
 09120 Genetic Information Processing
 
   09121 Transcription
 
   09122 Translation
 
   09123 Folding, sorting and degradation
 
   09124 Replication and repair
     03030 DNA replication [PATH:hsa03030]
     03410 Base excision repair [PATH:hsa03410]
     03420 Nucleotide excision repair [PATH:hsa03420]
     03430 Mismatch repair [PATH:hsa03430]
       6742 SSBP1; single stranded DNA binding protein 1
       5395 PMS2; PMS1 homolog 2, mismatch repair system component
       4292 MLH1; mutL homolog 1
       2956 MSH6; mutS homolog 6
       4436 MSH2; mutS homolog 2
       4437 MSH3; mutS homolog 3
       27030 MLH3; mutL homolog 3
       5981 RFC1; replication factor C subunit 1
       5984 RFC4; replication factor C subunit 4
       5982 RFC2; replication factor C subunit 2
       5985 RFC5; replication factor C subunit 5
       5983 RFC3; replication factor C subunit 3
       5111 PCNA; proliferating cell nuclear antigen
       9156 EXO1; exonuclease 1
       6117 RPA1; replication protein A1
       6118 RPA2; replication protein A2
       6119 RPA3; replication protein A3
       29935 RPA4; replication protein A4
       5424 POLD1; DNA polymerase delta 1, catalytic subunit
       5425 POLD2; DNA polymerase delta 2, accessory subunit
       10714 POLD3; DNA polymerase delta 3, accessory subunit
       57804 POLD4; DNA polymerase delta 4, accessory subunit
       3978 LIG1; DNA ligase 1
K03111 ssb; single-strand DNA-binding protein
K10858 PMS2; DNA mismatch repair protein PMS2
K08734 MLH1; DNA mismatch repair protein MLH1
K08737 MSH6; DNA mismatch repair protein MSH6
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08739 MLH3; DNA mismatch repair protein MLH3
K10754 RFC1; replication factor C subunit 1
K10755 RFC2_4; replication factor C subunit 2/4
K10755 RFC2_4; replication factor C subunit 2/4
K10756 RFC3_5; replication factor C subunit 3/5
K10756 RFC3_5; replication factor C subunit 3/5
K04802 PCNA; proliferating cell nuclear antigen
K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
K07466 RFA1; replication factor A1
K10739 RFA2; replication factor A2
K10740 RPA3; replication factor A3
K10741 RPA4; replication factor A4
K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
K02328 POLD2; DNA polymerase delta subunit 2
K03504 POLD3; DNA polymerase delta subunit 3
K03505 POLD4; DNA polymerase delta subunit 4
K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
     03440 Homologous recombination [PATH:hsa03440]
     03450 Non-homologous end-joining [PATH:hsa03450]
     03460 Fanconi anemia pathway [PATH:hsa03460]
 
 09130 Environmental Information Processing
 
 09140 Cellular Processes
 
 09150 Organismal Systems
 
 09160 Human Diseases
 
   09161 Cancer: overview
     05200 Pathways in cancer [PATH:hsa05200]
       1630 DCC; DCC netrin 1 receptor
       836 CASP3; caspase 3
       842 CASP9; caspase 9
       26060 APPL1; adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
       999 CDH1; cadherin 1
       1499 CTNNB1; catenin beta 1
       29119 CTNNA3; catenin alpha 3
       1495 CTNNA1; catenin alpha 1
       1496 CTNNA2; catenin alpha 2
       8312 AXIN1; axin 1
       8313 AXIN2; axin 2
       324 APC; APC regulator of WNT signaling pathway
       10297 APC2; APC regulator of WNT signaling pathway 2
       2932 GSK3B; glycogen synthase kinase 3 beta
       6932 TCF7; transcription factor 7
       83439 TCF7L1; transcription factor 7 like 1
       6934 TCF7L2; transcription factor 7 like 2
       51176 LEF1; lymphoid enhancer binding factor 1
       332 BIRC5; baculoviral IAP repeat containing 5
       4609 MYC; MYC proto-oncogene, bHLH transcription factor
       595 CCND1; cyclin D1
       7471 WNT1; Wnt family member 1
       7472 WNT2; Wnt family member 2
       7482 WNT2B; Wnt family member 2B
       7473 WNT3; Wnt family member 3
       89780 WNT3A; Wnt family member 3A
       54361 WNT4; Wnt family member 4
       7474 WNT5A; Wnt family member 5A
       81029 WNT5B; Wnt family member 5B
       7475 WNT6; Wnt family member 6
       7476 WNT7A; Wnt family member 7A
       7477 WNT7B; Wnt family member 7B
       7478 WNT8A; Wnt family member 8A
       7479 WNT8B; Wnt family member 8B
       7483 WNT9A; Wnt family member 9A
       7484 WNT9B; Wnt family member 9B
       7480 WNT10B; Wnt family member 10B
       80326 WNT10A; Wnt family member 10A
       7481 WNT11; Wnt family member 11
       51384 WNT16; Wnt family member 16
       8321 FZD1; frizzled class receptor 1
       8324 FZD7; frizzled class receptor 7
       2535 FZD2; frizzled class receptor 2
       7976 FZD3; frizzled class receptor 3
       8322 FZD4; frizzled class receptor 4
       7855 FZD5; frizzled class receptor 5
       8325 FZD8; frizzled class receptor 8
       8323 FZD6; frizzled class receptor 6
       11211 FZD10; frizzled class receptor 10
       8326 FZD9; frizzled class receptor 9
       4041 LRP5; LDL receptor related protein 5
       4040 LRP6; LDL receptor related protein 6
       1857 DVL3; dishevelled segment polarity protein 3
       1856 DVL2; dishevelled segment polarity protein 2
       1855 DVL1; dishevelled segment polarity protein 1
       10023 FRAT1; FRAT regulator of WNT signaling pathway 1
       23401 FRAT2; FRAT regulator of WNT signaling pathway 2
       2147 F2; coagulation factor II, thrombin
       183 AGT; angiotensinogen
       2149 F2R; coagulation factor II thrombin receptor
       9002 F2RL3; F2R like thrombin or trypsin receptor 3
       1902 LPAR1; lysophosphatidic acid receptor 1
       9170 LPAR2; lysophosphatidic acid receptor 2
       23566 LPAR3; lysophosphatidic acid receptor 3
       2846 LPAR4; lysophosphatidic acid receptor 4
       57121 LPAR5; lysophosphatidic acid receptor 5
       10161 LPAR6; lysophosphatidic acid receptor 6
       185 AGTR1; angiotensin II receptor type 1
       2768 GNA12; G protein subunit alpha 12
       10672 GNA13; G protein subunit alpha 13
       23365 ARHGEF12; Rho guanine nucleotide exchange factor 12
       9826 ARHGEF11; Rho guanine nucleotide exchange factor 11
       9138 ARHGEF1; Rho guanine nucleotide exchange factor 1
       57449 PLEKHG5; pleckstrin homology and RhoGEF domain containing G5
       387 RHOA; ras homolog family member A
       6093 ROCK1; Rho associated coiled-coil containing protein kinase 1
       9475 ROCK2; Rho associated coiled-coil containing protein kinase 2
       6387 CXCL12; C-X-C motif chemokine ligand 12
       7852 CXCR4; C-X-C motif chemokine receptor 4
       2770 GNAI1; G protein subunit alpha i1
       2773 GNAI3; G protein subunit alpha i3
       2771 GNAI2; G protein subunit alpha i2
       5731 PTGER1; prostaglandin E receptor 1
       5732 PTGER2; prostaglandin E receptor 2
       5733 PTGER3; prostaglandin E receptor 3
       5734 PTGER4; prostaglandin E receptor 4
       2778 GNAS; GNAS complex locus
       107 ADCY1; adenylate cyclase 1
       108 ADCY2; adenylate cyclase 2
       109 ADCY3; adenylate cyclase 3
       196883 ADCY4; adenylate cyclase 4
       111 ADCY5; adenylate cyclase 5
       112 ADCY6; adenylate cyclase 6
       113 ADCY7; adenylate cyclase 7
       114 ADCY8; adenylate cyclase 8
       115 ADCY9; adenylate cyclase 9
       5566 PRKACA; protein kinase cAMP-activated catalytic subunit alpha
       5567 PRKACB; protein kinase cAMP-activated catalytic subunit beta
       5568 PRKACG; protein kinase cAMP-activated catalytic subunit gamma
       2782 GNB1; G protein subunit beta 1
       2783 GNB2; G protein subunit beta 2
       2784 GNB3; G protein subunit beta 3
       59345 GNB4; G protein subunit beta 4
       10681 GNB5; G protein subunit beta 5
       54331 GNG2; G protein subunit gamma 2
       2785 GNG3; G protein subunit gamma 3
       2786 GNG4; G protein subunit gamma 4
       2787 GNG5; G protein subunit gamma 5
       2788 GNG7; G protein subunit gamma 7
       94235 GNG8; G protein subunit gamma 8
       2790 GNG10; G protein subunit gamma 10
       2791 GNG11; G protein subunit gamma 11
       55970 GNG12; G protein subunit gamma 12
       51764 GNG13; G protein subunit gamma 13
       2792 GNGT1; G protein subunit gamma transducin 1
       2793 GNGT2; G protein subunit gamma transducin 2
       1284 COL4A2; collagen type IV alpha 2 chain
       1286 COL4A4; collagen type IV alpha 4 chain
       1288 COL4A6; collagen type IV alpha 6 chain
       1282 COL4A1; collagen type IV alpha 1 chain
       1287 COL4A5; collagen type IV alpha 5 chain
       1285 COL4A3; collagen type IV alpha 3 chain
       284217 LAMA1; laminin subunit alpha 1
       3908 LAMA2; laminin subunit alpha 2
       3909 LAMA3; laminin subunit alpha 3
       3911 LAMA5; laminin subunit alpha 5
       3910 LAMA4; laminin subunit alpha 4
       3912 LAMB1; laminin subunit beta 1
       3913 LAMB2; laminin subunit beta 2
       3914 LAMB3; laminin subunit beta 3
       22798 LAMB4; laminin subunit beta 4
       3915 LAMC1; laminin subunit gamma 1
       3918 LAMC2; laminin subunit gamma 2
       10319 LAMC3; laminin subunit gamma 3
       2335 FN1; fibronectin 1
       3673 ITGA2; integrin subunit alpha 2
       3674 ITGA2B; integrin subunit alpha 2b
       3675 ITGA3; integrin subunit alpha 3
       3655 ITGA6; integrin subunit alpha 6
       3685 ITGAV; integrin subunit alpha V
       3688 ITGB1; integrin subunit beta 1
       5747 PTK2; protein tyrosine kinase 2
       5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
       5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
       8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
       5728 PTEN; phosphatase and tensin homolog
       4824 NKX3-1; NK3 homeobox 1
       207 AKT1; AKT serine/threonine kinase 1
       208 AKT2; AKT serine/threonine kinase 2
       10000 AKT3; AKT serine/threonine kinase 3
       1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
       3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
       8517 IKBKG; inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
       4792 NFKBIA; NFKB inhibitor alpha
       4790 NFKB1; nuclear factor kappa B subunit 1
       4791 NFKB2; nuclear factor kappa B subunit 2
       5970 RELA; RELA proto-oncogene, NF-kB subunit
       5743 PTGS2; prostaglandin-endoperoxide synthase 2
       4843 NOS2; nitric oxide synthase 2
       596 BCL2; BCL2 apoptosis regulator
       329 BIRC2; baculoviral IAP repeat containing 2
       330 BIRC3; baculoviral IAP repeat containing 3
       331 XIAP; X-linked inhibitor of apoptosis
       79444 BIRC7; baculoviral IAP repeat containing 7
       598 BCL2L1; BCL2 like 1
       7185 TRAF1; TNF receptor associated factor 1
       7186 TRAF2; TNF receptor associated factor 2
       7187 TRAF3; TNF receptor associated factor 3
       9618 TRAF4; TNF receptor associated factor 4
       7188 TRAF5; TNF receptor associated factor 5
       7189 TRAF6; TNF receptor associated factor 6
       2475 MTOR; mechanistic target of rapamycin kinase
       6198 RPS6KB1; ribosomal protein S6 kinase B1
       6199 RPS6KB2; ribosomal protein S6 kinase B2
       572 BAD; BCL2 associated agonist of cell death
       2308 FOXO1; forkhead box O1
       4193 MDM2; MDM2 proto-oncogene
       7157 TP53; tumor protein p53
       1027 CDKN1B; cyclin dependent kinase inhibitor 1B
       1026 CDKN1A; cyclin dependent kinase inhibitor 1A
       613 BCR; BCR activator of RhoGEF and GTPase
       25 ABL1; ABL proto-oncogene 1, non-receptor tyrosine kinase
       1398 CRK; CRK proto-oncogene, adaptor protein
       1399 CRKL; CRK like proto-oncogene, adaptor protein
       867 CBL; Cbl proto-oncogene
       6776 STAT5A; signal transducer and activator of transcription 5A
       6777 STAT5B; signal transducer and activator of transcription 5B
       5292 PIM1; Pim-1 proto-oncogene, serine/threonine kinase
       11040 PIM2; Pim-2 proto-oncogene, serine/threonine kinase
       3827 KNG1; kininogen 1
       1906 EDN1; endothelin 1
       623 BDKRB1; bradykinin receptor B1
       624 BDKRB2; bradykinin receptor B2
       1909 EDNRA; endothelin receptor type A
       1910 EDNRB; endothelin receptor type B
       2776 GNAQ; G protein subunit alpha q
       2767 GNA11; G protein subunit alpha 11
       23236 PLCB1; phospholipase C beta 1
       5330 PLCB2; phospholipase C beta 2
       5331 PLCB3; phospholipase C beta 3
       5332 PLCB4; phospholipase C beta 4
       5578 PRKCA; protein kinase C alpha
       5579 PRKCB; protein kinase C beta
       5582 PRKCG; protein kinase C gamma
       3558 IL2; interleukin 2
       3562 IL3; interleukin 3
       3565 IL4; interleukin 4
       3567 IL5; interleukin 5
       3569 IL6; interleukin 6
       3574 IL7; interleukin 7
       3592 IL12A; interleukin 12A
       3593 IL12B; interleukin 12B
       3596 IL13; interleukin 13
       3600 IL15; interleukin 15
       51561 IL23A; interleukin 23 subunit alpha
       2056 EPO; erythropoietin
       3439 IFNA1; interferon alpha 1
       3440 IFNA2; interferon alpha 2
       3441 IFNA4; interferon alpha 4
       3442 IFNA5; interferon alpha 5
       3443 IFNA6; interferon alpha 6
       3444 IFNA7; interferon alpha 7
       3445 IFNA8; interferon alpha 8
       3446 IFNA10; interferon alpha 10
       3447 IFNA13; interferon alpha 13
       3448 IFNA14; interferon alpha 14
       3449 IFNA16; interferon alpha 16
       3451 IFNA17; interferon alpha 17
       3452 IFNA21; interferon alpha 21
       3458 IFNG; interferon gamma
       3559 IL2RA; interleukin 2 receptor subunit alpha
       3560 IL2RB; interleukin 2 receptor subunit beta
       3561 IL2RG; interleukin 2 receptor subunit gamma
       3563 IL3RA; interleukin 3 receptor subunit alpha
       3566 IL4R; interleukin 4 receptor
       1439 CSF2RB; colony stimulating factor 2 receptor subunit beta
       3568 IL5RA; interleukin 5 receptor subunit alpha
       3570 IL6R; interleukin 6 receptor
       3572 IL6ST; interleukin 6 signal transducer
       3575 IL7R; interleukin 7 receptor
       3594 IL12RB1; interleukin 12 receptor subunit beta 1
       3595 IL12RB2; interleukin 12 receptor subunit beta 2
       3597 IL13RA1; interleukin 13 receptor subunit alpha 1
       3601 IL15RA; interleukin 15 receptor subunit alpha
       149233 IL23R; interleukin 23 receptor
       2057 EPOR; erythropoietin receptor
       3454 IFNAR1; interferon alpha and beta receptor subunit 1
       3455 IFNAR2; interferon alpha and beta receptor subunit 2
       3459 IFNGR1; interferon gamma receptor 1
       3460 IFNGR2; interferon gamma receptor 2
       27436 EML4; EMAP like 4
       238 ALK; ALK receptor tyrosine kinase
       10125 RASGRP1; RAS guanyl releasing protein 1
       10235 RASGRP2; RAS guanyl releasing protein 2
       25780 RASGRP3; RAS guanyl releasing protein 3
       115727 RASGRP4; RAS guanyl releasing protein 4
       3716 JAK1; Janus kinase 1
       3717 JAK2; Janus kinase 2
       3718 JAK3; Janus kinase 3
       6774 STAT3; signal transducer and activator of transcription 3
       6772 STAT1; signal transducer and activator of transcription 1
       6773 STAT2; signal transducer and activator of transcription 2
       6775 STAT4; signal transducer and activator of transcription 4
       6778 STAT6; signal transducer and activator of transcription 6
       7422 VEGFA; vascular endothelial growth factor A
       7423 VEGFB; vascular endothelial growth factor B
       5228 PGF; placental growth factor
       7424 VEGFC; vascular endothelial growth factor C
       2277 VEGFD; vascular endothelial growth factor D
       7039 TGFA; transforming growth factor alpha
       1950 EGF; epidermal growth factor
       1956 EGFR; epidermal growth factor receptor
       2064 ERBB2; erb-b2 receptor tyrosine kinase 2
       5154 PDGFA; platelet derived growth factor subunit A
       5155 PDGFB; platelet derived growth factor subunit B
       5156 PDGFRA; platelet derived growth factor receptor alpha
       5159 PDGFRB; platelet derived growth factor receptor beta
       3479 IGF1; insulin like growth factor 1
       3481 IGF2; insulin like growth factor 2
       3480 IGF1R; insulin like growth factor 1 receptor
       4254 KITLG; KIT ligand
       3815 KIT; KIT proto-oncogene, receptor tyrosine kinase
       2323 FLT3LG; fms related receptor tyrosine kinase 3 ligand
       2322 FLT3; fms related receptor tyrosine kinase 3
       3082 HGF; hepatocyte growth factor
       4233 MET; MET proto-oncogene, receptor tyrosine kinase
       2246 FGF1; fibroblast growth factor 1
       2247 FGF2; fibroblast growth factor 2
       2248 FGF3; fibroblast growth factor 3
       2249 FGF4; fibroblast growth factor 4
       8822 FGF17; fibroblast growth factor 17
       2251 FGF6; fibroblast growth factor 6
       2252 FGF7; fibroblast growth factor 7
       2253 FGF8; fibroblast growth factor 8
       2254 FGF9; fibroblast growth factor 9
       2255 FGF10; fibroblast growth factor 10
       8823 FGF16; fibroblast growth factor 16
       2250 FGF5; fibroblast growth factor 5
       8817 FGF18; fibroblast growth factor 18
       26281 FGF20; fibroblast growth factor 20
       27006 FGF22; fibroblast growth factor 22
       9965 FGF19; fibroblast growth factor 19
       26291 FGF21; fibroblast growth factor 21
       8074 FGF23; fibroblast growth factor 23
       2260 FGFR1; fibroblast growth factor receptor 1
       2263 FGFR2; fibroblast growth factor receptor 2
       2261 FGFR3; fibroblast growth factor receptor 3
       2264 FGFR4; fibroblast growth factor receptor 4
       2885 GRB2; growth factor receptor bound protein 2
       6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
       6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
       3265 HRAS; HRas proto-oncogene, GTPase
       3845 KRAS; KRAS proto-oncogene, GTPase
       4893 NRAS; NRAS proto-oncogene, GTPase
       369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
       673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
       5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
       5604 MAP2K1; mitogen-activated protein kinase kinase 1
       5605 MAP2K2; mitogen-activated protein kinase kinase 2
       5594 MAPK1; mitogen-activated protein kinase 1
       5595 MAPK3; mitogen-activated protein kinase 3
       3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
       2353 FOS; Fos proto-oncogene, AP-1 transcription factor subunit
       2113 ETS1; ETS proto-oncogene 1, transcription factor
       4312 MMP1; matrix metallopeptidase 1
       4313 MMP2; matrix metallopeptidase 2
       4318 MMP9; matrix metallopeptidase 9
       3576 CXCL8; C-X-C motif chemokine ligand 8
       1019 CDK4; cyclin dependent kinase 4
       9252 RPS6KA5; ribosomal protein S6 kinase A5
       5979 RET; ret proto-oncogene
       8030 CCDC6; coiled-coil domain containing 6
       8031 NCOA4; nuclear receptor coactivator 4
       4914 NTRK1; neurotrophic receptor tyrosine kinase 1
       7170 TPM3; tropomyosin 3
       7175 TPR; translocated promoter region, nuclear basket protein
       10342 TFG; trafficking from ER to golgi regulator
       11186 RASSF1; Ras association domain family member 1
       83593 RASSF5; Ras association domain family member 5
       6789 STK4; serine/threonine kinase 4
       1612 DAPK1; death associated protein kinase 1
       1613 DAPK3; death associated protein kinase 3
       23604 DAPK2; death associated protein kinase 2
       5335 PLCG1; phospholipase C gamma 1
       5336 PLCG2; phospholipase C gamma 2
       2002 ELK1; ETS transcription factor ELK1
       810 CALML3; calmodulin like 3
       805 CALM2; calmodulin 2
       808 CALM3; calmodulin 3
       801 CALM1; calmodulin 1
       163688 CALML6; calmodulin like 6
       51806 CALML5; calmodulin like 5
       91860 CALML4; calmodulin like 4
       815 CAMK2A; calcium/calmodulin dependent protein kinase II alpha
       817 CAMK2D; calcium/calmodulin dependent protein kinase II delta
       816 CAMK2B; calcium/calmodulin dependent protein kinase II beta
       818 CAMK2G; calcium/calmodulin dependent protein kinase II gamma
       5900 RALGDS; ral guanine nucleotide dissociation stimulator
       5898 RALA; RAS like proto-oncogene A
       5899 RALB; RAS like proto-oncogene B
       10928 RALBP1; ralA binding protein 1
       998 CDC42; cell division cycle 42
       5879 RAC1; Rac family small GTPase 1
       5880 RAC2; Rac family small GTPase 2
       5881 RAC3; Rac family small GTPase 3
       5337 PLD1; phospholipase D1
       5338 PLD2; phospholipase D2
       5599 MAPK8; mitogen-activated protein kinase 8
       5602 MAPK10; mitogen-activated protein kinase 10
       5601 MAPK9; mitogen-activated protein kinase 9
       7849 PAX8; paired box 8
       5468 PPARG; peroxisome proliferator activated receptor gamma
       6256 RXRA; retinoid X receptor alpha
       6257 RXRB; retinoid X receptor beta
       6258 RXRG; retinoid X receptor gamma
       5915 RARB; retinoic acid receptor beta
       2099 ESR1; estrogen receptor 1
       2100 ESR2; estrogen receptor 2
       8648 NCOA1; nuclear receptor coactivator 1
       8202 NCOA3; nuclear receptor coactivator 3
       6667 SP1; Sp1 transcription factor
       5467 PPARD; peroxisome proliferator activated receptor delta
       3728 JUP; junction plakoglobin
       7704 ZBTB16; zinc finger and BTB domain containing 16
       5914 RARA; retinoic acid receptor alpha
       890 CCNA2; cyclin A2
       8900 CCNA1; cyclin A1
       5371 PML; PML nuclear body scaffold
       861 RUNX1; RUNX family transcription factor 1
       862 RUNX1T1; RUNX1 partner transcriptional co-repressor 1
       6688 SPI1; Spi-1 proto-oncogene
       1050 CEBPA; CCAAT enhancer binding protein alpha
       1438 CSF2RA; colony stimulating factor 2 receptor subunit alpha
       1441 CSF3R; colony stimulating factor 3 receptor
       1436 CSF1R; colony stimulating factor 1 receptor
       1029 CDKN2A; cyclin dependent kinase inhibitor 2A
       1869 E2F1; E2F transcription factor 1
       1870 E2F2; E2F transcription factor 2
       1871 E2F3; E2F transcription factor 3
       4149 MAX; MYC associated factor X
       7709 ZBTB17; zinc finger and BTB domain containing 17
       1030 CDKN2B; cyclin dependent kinase inhibitor 2B
       1021 CDK6; cyclin dependent kinase 6
       894 CCND2; cyclin D2
       896 CCND3; cyclin D3
       1163 CKS1B; CDC28 protein kinase regulatory subunit 1B
       1164 CKS2; CDC28 protein kinase regulatory subunit 2
       6500 SKP1; S-phase kinase associated protein 1
       8454 CUL1; cullin 1
       9978 RBX1; ring-box 1
       6502 SKP2; S-phase kinase associated protein 2
       1017 CDK2; cyclin dependent kinase 2
       898 CCNE1; cyclin E1
       9134 CCNE2; cyclin E2
       5925 RB1; RB transcriptional corepressor 1
       1647 GADD45A; growth arrest and DNA damage inducible alpha
       4616 GADD45B; growth arrest and DNA damage inducible beta
       10912 GADD45G; growth arrest and DNA damage inducible gamma
       581 BAX; BCL2 associated X, apoptosis regulator
       578 BAK1; BCL2 antagonist/killer 1
       1643 DDB2; damage specific DNA binding protein 2
       51426 POLK; DNA polymerase kappa
       7015 TERT; telomerase reverse transcriptase
       7012 TERC; telomerase RNA component
       4286 MITF; melanocyte inducing transcription factor
       7040 TGFB1; transforming growth factor beta 1
       7042 TGFB2; transforming growth factor beta 2
       7043 TGFB3; transforming growth factor beta 3
       7046 TGFBR1; transforming growth factor beta receptor 1
       7048 TGFBR2; transforming growth factor beta receptor 2
       4087 SMAD2; SMAD family member 2
       4088 SMAD3; SMAD family member 3
       4089 SMAD4; SMAD family member 4
       2122 MECOM; MDS1 and EVI1 complex locus
       1487 CTBP1; C-terminal binding protein 1
       1488 CTBP2; C-terminal binding protein 2
       3065 HDAC1; histone deacetylase 1
       3066 HDAC2; histone deacetylase 2
       4292 MLH1; mutL homolog 1
       4436 MSH2; mutS homolog 2
       4437 MSH3; mutS homolog 3
       2956 MSH6; mutS homolog 6
       675 BRCA2; BRCA2 DNA repair associated
       5888 RAD51; RAD51 recombinase
       356 FASLG; Fas ligand
       355 FAS; Fas cell surface death receptor
       8772 FADD; Fas associated via death domain
       841 CASP8; caspase 8
       637 BID; BH3 interacting domain death agonist
       5366 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
       27113 BBC3; BCL2 binding component 3
       10018 BCL2L11; BCL2 like 11
       54205 CYCS; cytochrome c, somatic
       317 APAF1; apoptotic peptidase activating factor 1
       840 CASP7; caspase 7
       9817 KEAP1; kelch like ECH associated protein 1
       4780 NFE2L2; nuclear factor, erythroid 2 like 2
       3162 HMOX1; heme oxygenase 1
       1728 NQO1; NAD(P)H quinone dehydrogenase 1
       221357 GSTA5; glutathione S-transferase alpha 5
       2939 GSTA2; glutathione S-transferase alpha 2
       2941 GSTA4; glutathione S-transferase alpha 4
       119391 GSTO2; glutathione S-transferase omega 2
       2948 GSTM4; glutathione S-transferase mu 4
       2953 GSTT2; glutathione S-transferase theta 2 (gene/pseudogene)
       2952 GSTT1; glutathione S-transferase theta 1
       2947 GSTM3; glutathione S-transferase mu 3
       4257 MGST1; microsomal glutathione S-transferase 1
       4259 MGST3; microsomal glutathione S-transferase 3
       2944 GSTM1; glutathione S-transferase mu 1
       2949 GSTM5; glutathione S-transferase mu 5
       4258 MGST2; microsomal glutathione S-transferase 2
       2938 GSTA1; glutathione S-transferase alpha 1
       2946 GSTM2; glutathione S-transferase mu 2
       2940 GSTA3; glutathione S-transferase alpha 3
       9446 GSTO1; glutathione S-transferase omega 1
       653689 GSTT2B; glutathione S-transferase theta 2B
       2950 GSTP1; glutathione S-transferase pi 1
       7296 TXNRD1; thioredoxin reductase 1
       114112 TXNRD3; thioredoxin reductase 3
       10587 TXNRD2; thioredoxin reductase 2
       7428 VHL; von Hippel-Lindau tumor suppressor
       6921 ELOC; elongin C
       6923 ELOB; elongin B
       8453 CUL2; cullin 2
       54583 EGLN1; egl-9 family hypoxia inducible factor 1
       112399 EGLN3; egl-9 family hypoxia inducible factor 3
       112398 EGLN2; egl-9 family hypoxia inducible factor 2
       2271 FH; fumarate hydratase
       3091 HIF1A; hypoxia inducible factor 1 subunit alpha
       2034 EPAS1; endothelial PAS domain protein 1
       405 ARNT; aryl hydrocarbon receptor nuclear translocator
       9915 ARNT2; aryl hydrocarbon receptor nuclear translocator 2
       1387 CREBBP; CREB binding protein
       2033 EP300; E1A binding protein p300
       6513 SLC2A1; solute carrier family 2 member 1
       182 JAG1; jagged canonical Notch ligand 1
       3714 JAG2; jagged canonical Notch ligand 2
       10683 DLL3; delta like canonical Notch ligand 3
       28514 DLL1; delta like canonical Notch ligand 1
       54567 DLL4; delta like canonical Notch ligand 4
       4851 NOTCH1; notch receptor 1
       4853 NOTCH2; notch receptor 2
       4854 NOTCH3; notch receptor 3
       4855 NOTCH4; notch receptor 4
       3280 HES1; hes family bHLH transcription factor 1
       388585 HES5; hes family bHLH transcription factor 5
       26508 HEYL; hes related family bHLH transcription factor with YRPW motif like
       23462 HEY1; hes related family bHLH transcription factor with YRPW motif 1
       23493 HEY2; hes related family bHLH transcription factor with YRPW motif 2
       2324 FLT4; fms related receptor tyrosine kinase 4
       6469 SHH; sonic hedgehog signaling molecule
       5727 PTCH1; patched 1
       6608 SMO; smoothened, frizzled class receptor
       374654 KIF7; kinesin family member 7
       51684 SUFU; SUFU negative regulator of hedgehog signaling
       2735 GLI1; GLI family zinc finger 1
       2736 GLI2; GLI family zinc finger 2
       2737 GLI3; GLI family zinc finger 3
       650 BMP2; bone morphogenetic protein 2
       652 BMP4; bone morphogenetic protein 4
       64399 HHIP; hedgehog interacting protein
       8643 PTCH2; patched 2
       367 AR; androgen receptor
       3320 HSP90AA1; heat shock protein 90 alpha family class A member 1
       3326 HSP90AB1; heat shock protein 90 alpha family class B member 1
       7184 HSP90B1; heat shock protein 90 beta family member 1
       354 KLK3; kallikrein related peptidase 3
K06765 DCC; deleted in colorectal carcinoma
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K08733 APPL1; DCC-interacting protein 13 alpha
K05689 CDH1; cadherin 1, type 1, E-cadherin
K02105 CTNNB1; catenin beta 1
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K03209 WNT1; wingless-type MMTV integration site family, member 1
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00182 WNT2; wingless-type MMTV integration site family, member 2
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00312 WNT3; wingless-type MMTV integration site family, member 3
K00408 WNT4; wingless-type MMTV integration site family, member 4
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00444 WNT5; wingless-type MMTV integration site family, member 5
K00445 WNT6; wingless-type MMTV integration site family, member 6
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00572 WNT7; wingless-type MMTV integration site family, member 7
K00714 WNT8; wingless-type MMTV integration site family, member 8
K00714 WNT8; wingless-type MMTV integration site family, member 8
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01064 WNT9; wingless-type MMTV integration site family, member 9
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01357 WNT10; wingless-type MMTV integration site family, member 10
K01384 WNT11; wingless-type MMTV integration site family, member 11
K01558 WNT16; wingless-type MMTV integration site family, member 16
K02432 FZD1_7; frizzled 1/7
K02432 FZD1_7; frizzled 1/7
K02235 FZD2; frizzled 2
K02329 FZD3; frizzled 3
K02354 FZD4; frizzled 4
K02375 FZD5_8; frizzled 5/8
K02375 FZD5_8; frizzled 5/8
K02376 FZD6; frizzled 6
K02842 FZD9_10; frizzled 9/10
K02842 FZD9_10; frizzled 9/10
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K03068 LRP5_6; low density lipoprotein receptor-related protein 5/6
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K02353 DVL; segment polarity protein dishevelled
K03069 FRAT1; frequently rearranged in advanced T-cell lymphomas 1
K03096 FRAT2; frequently rearranged in advanced T-cell lymphomas 2
K01313 F2; coagulation factor II (thrombin) [EC:3.4.21.5]
K09821 AGT; angiotensinogen
K03914 F2R; coagulation factor II (thrombin) receptor
K04236 F2RL3; coagulation factor II (thrombin) receptor-like 3
K04289 LPAR1; lysophosphatidic acid receptor 1
K04291 LPAR2; lysophosphatidic acid receptor 2
K04294 LPAR3; lysophosphatidic acid receptor 3
K04275 LPAR4; lysophosphatidic acid receptor 4
K08390 LPAR5; lysophosphatidic acid receptor 5
K04273 LPAR6; lysophosphatidic acid receptor 6
K04166 AGTR1; angiotensin II receptor type 1
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K07532 ARHGEF12; Rho guanine nucleotide exchange factor 12
K12331 ARHGEF11; Rho guanine nucleotide exchange factor 11
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K19464 PLEKHG5; pleckstrin homology domain-containing family G member 5
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K10031 CXCL12; C-X-C motif chemokine 12
K04189 CXCR4; C-X-C chemokine receptor type 4
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04258 PTGER1; prostaglandin E receptor 1
K04259 PTGER2; prostaglandin E receptor 2
K04260 PTGER3; prostaglandin E receptor 3
K04261 PTGER4; prostaglandin E receptor 4
K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
K04537 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
K04540 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
K04543 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
K04544 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
K04547 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
K04548 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1
K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K06237 COL4A; collagen type IV alpha
K05637 LAMA1_2; laminin, alpha 1/2
K05637 LAMA1_2; laminin, alpha 1/2
K06240 LAMA3_5; laminin, alpha 3/5
K06240 LAMA3_5; laminin, alpha 3/5
K06241 LAMA4; laminin, alpha 4
K05636 LAMB1; laminin, beta 1
K06243 LAMB2; laminin, beta 2
K06244 LAMB3; laminin, beta 3
K06245 LAMB4; laminin, beta 4
K05635 LAMC1; laminin, gamma 1
K06246 LAMC2; laminin, gamma 2
K06247 LAMC3; laminin, gamma 3
K05717 FN1; fibronectin 1
K06481 ITGA2; integrin alpha 2
K06476 ITGA2B; integrin alpha 2B
K06482 ITGA3; integrin alpha 3
K06485 ITGA6; integrin alpha 6
K06487 ITGAV; integrin alpha V
K05719 ITGB1; integrin beta 1
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K09348 NKX3-1; homeobox protein Nkx-3.1
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K04735 RELA; transcription factor p65
K11987 PTGS2; prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1]
K13241 NOS2; nitric-oxide synthase, inducible [EC:1.14.13.39]
K02161 BCL2; apoptosis regulator Bcl-2
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K03172 TRAF1; TNF receptor-associated factor 1
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K03174 TRAF3; TNF receptor-associated factor 3
K09848 TRAF4; TNF receptor-associated factor 4
K09849 TRAF5; TNF receptor-associated factor 5
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K07201 FOXO1; forkhead box protein O1
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53; tumor protein p53
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K08878 BCR1; breakpoint cluster region protein [EC:2.7.11.1]
K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K04702 PIM1; proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1]
K08806 PIM2; proto-oncogene serine/threonine-protein kinase Pim-2 [EC:2.7.11.1]
K03898 KNG; kininogen
K16366 EDN1; endothelin-1
K03915 BDKRB1; bradykinin receptor B1
K03916 BDKRB2; bradykinin receptor B2
K04197 EDNRA; endothelin receptor type A
K04198 EDNRB; endothelin receptor type B
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K05429 IL2; interleukin 2
K04736 IL3; interleukin 3
K05430 IL4; interleukin 4
K05428 IL5; interleukin 5
K05405 IL6; interleukin 6
K05431 IL7; interleukin 7
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K05435 IL13; interleukin 13
K05433 IL15; interleukin 15
K05426 IL23A; interleukin 23 subunit alpha
K05437 EPO; erythropoietin
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K04687 IFNG; interferon gamma
K05068 IL2RA; interleukin 2 receptor alpha
K05069 IL2RB; interleukin 2 receptor beta
K05070 IL2RG; interleukin 2 receptor gamma
K04737 IL3RA; interleukin 3 receptor alpha
K05071 IL4R; interleukin 4 receptor
K04738 CSF2RB; cytokine receptor common subunit beta
K05067 IL5RA. CD125; interleukin 5 receptor alpha
K05055 IL6R; interleukin 6 receptor
K05060 IL6ST; interleukin 6 signal transducer
K05072 IL7R; interleukin 7 receptor
K05063 IL12RB1; interleukin 12 receptor beta-1
K05064 IL12RB2; interleukin 12 receptor beta-2
K05076 IL13RA1; interleukin 13 receptor alpha-1
K05074 IL15RA; interleukin 15 receptor alpha
K05065 IL23R; interleukin 23 receptor
K05079 EPOR; erythropoietin receptor
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K05132 IFNGR1; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K15420 EML4; echinoderm microtubule-associated protein-like 4
K05119 ALK; anaplastic lymphoma kinase [EC:2.7.10.1]
K04350 RASGRP1; RAS guanyl-releasing protein 1
K12361 RASGRP2; RAS guanyl-releasing protein 2
K12362 RASGRP3; RAS guanyl-releasing protein 3
K12363 RASGRP4; RAS guanyl-releasing protein 4
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K11222 STAT4; signal transducer and activator of transcription 4
K11225 STAT6; signal transducer and activator of transcription 6
K05448 VEGFA; vascular endothelial growth factor A
K16858 VEGFB; vascular endothelial growth factor B
K16859 PGF; placenta growth factor
K05449 VEGFC_D; vascular endothelial growth factor C/D
K05449 VEGFC_D; vascular endothelial growth factor C/D
K08774 TGFA; transforming growth factor, alpha
K04357 EGF; epidermal growth factor
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K05459 IGF1; insulin-like growth factor 1
K13769 IGF2; insulin-like growth factor 2
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K05461 KITLG; KIT ligand
K05091 KIT; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
K05454 FLT3LG; fms-related tyrosine kinase 3 ligand
K05092 FLT3; fms-related tyrosine kinase 3 [EC:2.7.10.1]
K05460 HGF; hepatocyte growth factor
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K18496 FGF1; fibroblast growth factor 1
K18497 FGF2; fibroblast growth factor 2
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K04358 FGF; fibroblast growth factor
K22603 FGF19; fibroblast growth factor 19
K22429 FGF21; fibroblast growth factor 21
K22428 FGF23; fibroblast growth factor 23
K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K05094 FGFR3; fibroblast growth factor receptor 3 [EC:2.7.10.1]
K05095 FGFR4; fibroblast growth factor receptor 4 [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K02678 ETS1; C-ets-1
K01388 MMP1; matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7]
K01398 MMP2; matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K10030 IL8; interleukin 8
K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
K04445 RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
K09288 CCDC6; coiled-coil domain-containing protein 6
K09289 NCOA4; nuclear receptor coactivator 4
K03176 NTRK1; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]
K09290 TPM3; tropomyosin 3
K09291 TPR; nucleoprotein TPR
K09292 TFG; protein TFG
K09850 RASSF1; Ras association domain-containing protein 1
K08015 RASSF5; Ras association domain-containing protein 5
K04411 STK4; serine/threonine kinase 4
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K08803 DAPK; death-associated protein kinase [EC:2.7.11.1]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K04375 ELK1; ETS domain-containing protein Elk-1
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K08773 RALBP1; RalA-binding protein 1
K04393 CDC42; cell division control protein 42
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K09293 PAX8; paired box protein 8
K08530 NR1C3; peroxisome proliferator-activated receptor gamma
K08524 RXRA; retinoid X receptor alpha
K08525 RXRB; retinoid X receptor beta
K08526 RXRG; retinoid X receptor gamma
K08528 RARB; retinoic acid receptor beta
K08550 ESR1; estrogen receptor alpha
K08551 ESR2; estrogen receptor beta
K09101 NCOA1; nuclear receptor coactivator 1 [EC:2.3.1.48]
K11256 NCOA3; nuclear receptor coactivator 3 [EC:2.3.1.48]
K04684 SP1; transcription factor Sp1
K04504 NR1C2; peroxisome proliferator-activated receptor delta
K10056 JUP; junction plakoglobin
K10055 ZBTB16; zinc finger and BTB domain-containing protein 16
K08527 RARA; retinoic acid receptor alpha
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K10054 PML; probable transcription factor PML
K08367 RUNX1; runt-related transcription factor 1
K10053 RUNX1T1; CBFA2/RNUX1 translocation partner 1
K09438 SPI1; transcription factor PU.1
K09055 CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
K05066 CSF2RA; granulocyte-macrophage colony-stimulating factor receptor alpha
K05061 CSF3R; granulocyte colony-stimulating factor receptor
K05090 CSF1R; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K04453 MAX; Max protein
K10500 ZBTB17; zinc finger and BTB domain-containing protein 17
K04685 CDKN2B; cyclin-dependent kinase inhibitor 2B
K02091 CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]
K10151 CCND2; G1/S-specific cyclin-D2
K10152 CCND3; G1/S-specific cyclin-D3
K02219 CKS1; cyclin-dependent kinase regulatory subunit CKS1
K02219 CKS1; cyclin-dependent kinase regulatory subunit CKS1
K03094 SKP1; S-phase kinase-associated protein 1
K03347 CUL1; cullin 1
K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K06618 RB1; retinoblastoma-associated protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
K22183 TERC; telomerase RNA component
K09455 MITF; microphthalmia-associated transcription factor
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K04462 MECOM; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
K04496 CTBP; C-terminal binding protein
K04496 CTBP; C-terminal binding protein
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K06067 HDAC1_2; histone deacetylase 1/2 [EC:3.5.1.98]
K08734 MLH1; DNA mismatch repair protein MLH1
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K08775 BRCA2; breast cancer 2 susceptibility protein
K04482 RAD51; DNA repair protein RAD51
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K10131 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
K10132 BBC3; Bcl-2-binding component 3
K16341 BCL2L11; Bcl-2-like protein 11
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K10456 KLHL19; kelch-like protein 19
K05638 NFE2L2; nuclear factor erythroid 2-related factor 2
K00510 HMOX1; heme oxygenase 1 [EC:1.14.14.18]
K00355 NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K22182 TXNRD; thioredoxin reductase (NADPH) [EC:1.8.1.9]
K03871 VHL; von Hippel-Lindau disease tumor supressor
K03872 ELOC; elongin-C
K03873 ELOB; elongin-B
K03870 CUL2; cullin 2
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K09592 EGLN; hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29]
K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
K08268 HIF1A; hypoxia-inducible factor 1 alpha
K09095 HIF2A; hypoxia-inducible factor 2 alpha
K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
K15589 ARNT2; aryl hydrocarbon receptor nuclear translocator 2
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K07299 SLC2A1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K06052 JAG1; jagged-1
K21635 JAG2; jagged-2
K06051 DLL; delta
K06051 DLL; delta
K06051 DLL; delta
K02599 NOTCH1; Notch 1
K20994 NOTCH2; Notch 2
K20995 NOTCH3; Notch 3
K20996 NOTCH4; Notch 4
K06054 HES1; hairy and enhancer of split 1
K06055 HES5; hairy and enhancer of split 5
K09091 HEY; hairy and enhancer of split related with YRPW motif
K09091 HEY; hairy and enhancer of split related with YRPW motif
K09091 HEY; hairy and enhancer of split related with YRPW motif
K05097 FLT4; FMS-like tyrosine kinase 4 [EC:2.7.10.1]
K11988 SHH; sonic hedgehog
K06225 PTCH1; patched 1
K06226 SMO; smoothened
K18806 KIF7; kinesin family member 7
K06229 SUFU; suppressor of fused
K16797 GLI1; zinc finger protein GLI1
K16798 GLI2; zinc finger protein GLI2
K06230 GLI3; zinc finger protein GLI3
K21283 BMP2; bone morphogenetic protein 2
K04662 BMP4; bone morphogenetic protein 4
K06231 HHIP; hedgehog interacting protein
K11101 PTCH2; patched 2
K08557 AR; androgen receptor
K04079 HSP90A; molecular chaperone HtpG
K04079 HSP90A; molecular chaperone HtpG
K09487 HSP90B; heat shock protein 90kDa beta
K01351 KLK3; semenogelase [EC:3.4.21.77]
     05202 Transcriptional misregulation in cancer [PATH:hsa05202]
     05206 MicroRNAs in cancer [PATH:hsa05206]
     05205 Proteoglycans in cancer [PATH:hsa05205]
     05204 Chemical carcinogenesis [PATH:hsa05204]
     05203 Viral carcinogenesis [PATH:hsa05203]
     05230 Central carbon metabolism in cancer [PATH:hsa05230]
     05231 Choline metabolism in cancer [PATH:hsa05231]
     05235 PD-L1 expression and PD-1 checkpoint pathway in cancer [PATH:hsa05235]
 
   09162 Cancer: specific types
     05210 Colorectal cancer [PATH:hsa05210]
       2932 GSK3B; glycogen synthase kinase 3 beta
       8312 AXIN1; axin 1
       8313 AXIN2; axin 2
       1499 CTNNB1; catenin beta 1
       324 APC; APC regulator of WNT signaling pathway
       10297 APC2; APC regulator of WNT signaling pathway 2
       6932 TCF7; transcription factor 7
       83439 TCF7L1; transcription factor 7 like 1
       6934 TCF7L2; transcription factor 7 like 2
       51176 LEF1; lymphoid enhancer binding factor 1
       332 BIRC5; baculoviral IAP repeat containing 5
       4609 MYC; MYC proto-oncogene, bHLH transcription factor
       595 CCND1; cyclin D1
       3845 KRAS; KRAS proto-oncogene, GTPase
       5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
       5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
       8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
       207 AKT1; AKT serine/threonine kinase 1
       208 AKT2; AKT serine/threonine kinase 2
       10000 AKT3; AKT serine/threonine kinase 3
       572 BAD; BCL2 associated agonist of cell death
       842 CASP9; caspase 9
       369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
       673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
       5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
       5604 MAP2K1; mitogen-activated protein kinase kinase 1
       5605 MAP2K2; mitogen-activated protein kinase kinase 2
       5594 MAPK1; mitogen-activated protein kinase 1
       5595 MAPK3; mitogen-activated protein kinase 3
       3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
       2353 FOS; Fos proto-oncogene, AP-1 transcription factor subunit
       5900 RALGDS; ral guanine nucleotide dissociation stimulator
       5898 RALA; RAS like proto-oncogene A
       5899 RALB; RAS like proto-oncogene B
       5879 RAC1; Rac family small GTPase 1
       5880 RAC2; Rac family small GTPase 2
       5881 RAC3; Rac family small GTPase 3
       387 RHOA; ras homolog family member A
       5599 MAPK8; mitogen-activated protein kinase 8
       5602 MAPK10; mitogen-activated protein kinase 10
       5601 MAPK9; mitogen-activated protein kinase 9
       1630 DCC; DCC netrin 1 receptor
       836 CASP3; caspase 3
       26060 APPL1; adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
       7040 TGFB1; transforming growth factor beta 1
       7042 TGFB2; transforming growth factor beta 2
       7043 TGFB3; transforming growth factor beta 3
       7046 TGFBR1; transforming growth factor beta receptor 1
       7048 TGFBR2; transforming growth factor beta receptor 2
       4087 SMAD2; SMAD family member 2
       4088 SMAD3; SMAD family member 3
       4089 SMAD4; SMAD family member 4
       4292 MLH1; mutL homolog 1
       4436 MSH2; mutS homolog 2
       4437 MSH3; mutS homolog 3
       2956 MSH6; mutS homolog 6
       581 BAX; BCL2 associated X, apoptosis regulator
       5366 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
       10018 BCL2L11; BCL2 like 11
       27113 BBC3; BCL2 binding component 3
       596 BCL2; BCL2 apoptosis regulator
       54205 CYCS; cytochrome c, somatic
       7157 TP53; tumor protein p53
       1026 CDKN1A; cyclin dependent kinase inhibitor 1A
       1647 GADD45A; growth arrest and DNA damage inducible alpha
       4616 GADD45B; growth arrest and DNA damage inducible beta
       10912 GADD45G; growth arrest and DNA damage inducible gamma
       578 BAK1; BCL2 antagonist/killer 1
       1643 DDB2; damage specific DNA binding protein 2
       51426 POLK; DNA polymerase kappa
       1950 EGF; epidermal growth factor
       7039 TGFA; transforming growth factor alpha
       2069 EREG; epiregulin
       374 AREG; amphiregulin
       1956 EGFR; epidermal growth factor receptor
       2885 GRB2; growth factor receptor bound protein 2
       6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
       6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
       3265 HRAS; HRas proto-oncogene, GTPase
       4893 NRAS; NRAS proto-oncogene, GTPase
       2475 MTOR; mechanistic target of rapamycin kinase
       6198 RPS6KB1; ribosomal protein S6 kinase B1
       6199 RPS6KB2; ribosomal protein S6 kinase B2
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K02157 AXIN1; axin 1
K04385 AXIN2; axin 2
K02105 CTNNB1; catenin beta 1
K02085 APC; adenomatosis polyposis coli protein
K02085 APC; adenomatosis polyposis coli protein
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K04377 MYC; Myc proto-oncogene protein
K04503 CCND1; G1/S-specific cyclin-D1
K07827 KRAS; GTPase KRas
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02158 BAD; Bcl-2-antagonist of cell death
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K04379 FOS; proto-oncogene protein c-fos
K08732 RALGDS; ral guanine nucleotide dissociation stimulator
K07834 RALA; Ras-related protein Ral-A
K07835 RALB; Ras-related protein Ral-B
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04513 RHOA; Ras homolog gene family, member A
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K06765 DCC; deleted in colorectal carcinoma
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K08733 APPL1; DCC-interacting protein 13 alpha
K13375 TGFB1; transforming growth factor beta-1
K13376 TGFB2; transforming growth factor beta-2
K13377 TGFB3; transforming growth factor beta-3
K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
K04388 TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]
K04500 SMAD2; mothers against decapentaplegic homolog 2
K23605 SMAD3; mothers against decapentaplegic homolog 3
K04501 SMAD4; mothers against decapentaplegic homolog 4
K08734 MLH1; DNA mismatch repair protein MLH1
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K02159 BAX; apoptosis regulator BAX
K10131 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
K16341 BCL2L11; Bcl-2-like protein 11
K10132 BBC3; Bcl-2-binding component 3
K02161 BCL2; apoptosis regulator Bcl-2
K08738 CYC; cytochrome c
K04451 TP53; tumor protein p53
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K04402 GADD45; growth arrest and DNA-damage-inducible protein
K14021 BAK; Bcl-2 homologous antagonist/killer
K10140 DDB2; DNA damage-binding protein 2
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K04357 EGF; epidermal growth factor
K08774 TGFA; transforming growth factor, alpha
K09784 EREG; epiregulin
K09782 AREG; amphiregulin
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K07828 NRAS; GTPase NRas
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
     05212 Pancreatic cancer [PATH:hsa05212]
     05225 Hepatocellular carcinoma [PATH:hsa05225]
     05226 Gastric cancer [PATH:hsa05226]
     05214 Glioma [PATH:hsa05214]
     05216 Thyroid cancer [PATH:hsa05216]
     05221 Acute myeloid leukemia [PATH:hsa05221]
     05220 Chronic myeloid leukemia [PATH:hsa05220]
     05217 Basal cell carcinoma [PATH:hsa05217]
     05218 Melanoma [PATH:hsa05218]
     05211 Renal cell carcinoma [PATH:hsa05211]
     05219 Bladder cancer [PATH:hsa05219]
     05215 Prostate cancer [PATH:hsa05215]
     05213 Endometrial cancer [PATH:hsa05213]
     05224 Breast cancer [PATH:hsa05224]
     05222 Small cell lung cancer [PATH:hsa05222]
     05223 Non-small cell lung cancer [PATH:hsa05223]
 
   09163 Immune disease
 
   09164 Neurodegenerative disease
 
   09165 Substance dependence
 
   09166 Cardiovascular disease
 
   09167 Endocrine and metabolic disease
 
   09171 Infectious disease: bacterial
 
   09172 Infectious disease: viral
 
   09174 Infectious disease: parasitic
 
   09175 Drug resistance: antimicrobial
 
   09176 Drug resistance: antineoplastic
     01521 EGFR tyrosine kinase inhibitor resistance [PATH:hsa01521]
     01524 Platinum drug resistance [PATH:hsa01524]
       1317 SLC31A1; solute carrier family 31 member 1
       540 ATP7B; ATPase copper transporting beta
       538 ATP7A; ATPase copper transporting alpha
       221357 GSTA5; glutathione S-transferase alpha 5
       2939 GSTA2; glutathione S-transferase alpha 2
       2941 GSTA4; glutathione S-transferase alpha 4
       119391 GSTO2; glutathione S-transferase omega 2
       2948 GSTM4; glutathione S-transferase mu 4
       2953 GSTT2; glutathione S-transferase theta 2 (gene/pseudogene)
       2952 GSTT1; glutathione S-transferase theta 1
       2947 GSTM3; glutathione S-transferase mu 3
       4257 MGST1; microsomal glutathione S-transferase 1
       4259 MGST3; microsomal glutathione S-transferase 3
       2944 GSTM1; glutathione S-transferase mu 1
       2949 GSTM5; glutathione S-transferase mu 5
       4258 MGST2; microsomal glutathione S-transferase 2
       2938 GSTA1; glutathione S-transferase alpha 1
       2946 GSTM2; glutathione S-transferase mu 2
       2940 GSTA3; glutathione S-transferase alpha 3
       9446 GSTO1; glutathione S-transferase omega 1
       653689 GSTT2B; glutathione S-transferase theta 2B
       2950 GSTP1; glutathione S-transferase pi 1
       1244 ABCC2; ATP binding cassette subfamily C member 2
       5429 POLH; DNA polymerase eta
       5980 REV3L; REV3 like, DNA directed polymerase zeta catalytic subunit
       4436 MSH2; mutS homolog 2
       4437 MSH3; mutS homolog 3
       2956 MSH6; mutS homolog 6
       4292 MLH1; mutL homolog 1
       7507 XPA; XPA, DNA damage recognition and repair factor
       2067 ERCC1; ERCC excision repair 1, endonuclease non-catalytic subunit
       7155 TOP2B; DNA topoisomerase II beta
       7153 TOP2A; DNA topoisomerase II alpha
       672 BRCA1; BRCA1 DNA repair associated
       472 ATM; ATM serine/threonine kinase
       7157 TP53; tumor protein p53
       1029 CDKN2A; cyclin dependent kinase inhibitor 2A
       4193 MDM2; MDM2 proto-oncogene
       355 FAS; Fas cell surface death receptor
       581 BAX; BCL2 associated X, apoptosis regulator
       578 BAK1; BCL2 antagonist/killer 1
       5366 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
       27113 BBC3; BCL2 binding component 3
       356 FASLG; Fas ligand
       8772 FADD; Fas associated via death domain
       841 CASP8; caspase 8
       836 CASP3; caspase 3
       637 BID; BH3 interacting domain death agonist
       329 BIRC2; baculoviral IAP repeat containing 2
       330 BIRC3; baculoviral IAP repeat containing 3
       331 XIAP; X-linked inhibitor of apoptosis
       332 BIRC5; baculoviral IAP repeat containing 5
       2064 ERBB2; erb-b2 receptor tyrosine kinase 2
       5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
       5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
       8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
       5170 PDPK1; 3-phosphoinositide dependent protein kinase 1
       207 AKT1; AKT serine/threonine kinase 1
       208 AKT2; AKT serine/threonine kinase 2
       10000 AKT3; AKT serine/threonine kinase 3
       1026 CDKN1A; cyclin dependent kinase inhibitor 1A
       4217 MAP3K5; mitogen-activated protein kinase kinase kinase 5
       5594 MAPK1; mitogen-activated protein kinase 1
       5595 MAPK3; mitogen-activated protein kinase 3
       572 BAD; BCL2 associated agonist of cell death
       598 BCL2L1; BCL2 like 1
       596 BCL2; BCL2 apoptosis regulator
       54205 CYCS; cytochrome c, somatic
       317 APAF1; apoptotic peptidase activating factor 1
       842 CASP9; caspase 9
K14686 SLC31A1; solute carrier family 31 (copper transporter), member 1
K17686 copA; P-type Cu+ transporter [EC:7.2.2.8]
K17686 copA; P-type Cu+ transporter [EC:7.2.2.8]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K00799 GST; glutathione S-transferase [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K05666 ABCC2; ATP-binding cassette, subfamily C (CFTR/MRP), member 2
K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K08734 MLH1; DNA mismatch repair protein MLH1
K10847 XPA; DNA-repair protein complementing XP-A cells
K10849 ERCC1; DNA excision repair protein ERCC-1
K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K04451 TP53; tumor protein p53
K06621 CDKN2A; cyclin-dependent kinase inhibitor 2A
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K10131 PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1
K10132 BBC3; Bcl-2-binding component 3
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04726 BID; BH3 interacting domain death agonist
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K08731 BIRC5; baculoviral IAP repeat-containing protein 5
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K04426 MAP3K5; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K02158 BAD; Bcl-2-antagonist of cell death
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator Bcl-2
K08738 CYC; cytochrome c
K02084 APAF1; apoptotic protease-activating factor
K04399 CASP9; caspase 9 [EC:3.4.22.62]
     01523 Antifolate resistance [PATH:hsa01523]
     01522 Endocrine resistance [PATH:hsa01522]
 
 09180 Brite Hierarchies
 
   09181 Protein families: metabolism
 
   09182 Protein families: genetic information processing
     03000 Transcription factors [BR:hsa03000]
     03021 Transcription machinery [BR:hsa03021]
     03019 Messenger RNA biogenesis [BR:hsa03019]
     03041 Spliceosome [BR:hsa03041]
     03011 Ribosome [BR:hsa03011]
     03009 Ribosome biogenesis [BR:hsa03009]
     03016 Transfer RNA biogenesis [BR:hsa03016]
     03012 Translation factors [BR:hsa03012]
     03110 Chaperones and folding catalysts [BR:hsa03110]
     04131 Membrane trafficking [BR:hsa04131]
     04121 Ubiquitin system [BR:hsa04121]
     03051 Proteasome [BR:hsa03051]
     03032 DNA replication proteins [BR:hsa03032]
     03036 Chromosome and associated proteins [BR:hsa03036]
     03400 DNA repair and recombination proteins [BR:hsa03400]
       4255 MGMT; O-6-methylguanine-DNA methyltransferase
       121642 ALKBH2; alkB homolog 2, alpha-ketoglutarate dependent dioxygenase
       221120 ALKBH3; alkB homolog 3, alpha-ketoglutarate dependent dioxygenase
       10973 ASCC3; activating signal cointegrator 1 complex subunit 3
       1407 CRY1; cryptochrome circadian regulator 1
       1408 CRY2; cryptochrome circadian regulator 2
       7374 UNG; uracil DNA glycosylase
       10309 CCNO; cyclin O
       6996 TDG; thymine DNA glycosylase
       4350 MPG; N-methylpurine DNA glycosylase
       23583 SMUG1; single-strand-selective monofunctional uracil-DNA glycosylase 1
       4595 MUTYH; mutY DNA glycosylase
       8930 MBD4; methyl-CpG binding domain 4, DNA glycosylase
       4968 OGG1; 8-oxoguanine DNA glycosylase
       79661 NEIL1; nei like DNA glycosylase 1
       252969 NEIL2; nei like DNA glycosylase 2
       55247 NEIL3; nei like DNA glycosylase 3
       4913 NTHL1; nth like DNA glycosylase 1
       328 APEX1; apurinic/apyrimidinic endodeoxyribonuclease 1
       27301 APEX2; apurinic/apyrimidinic endodeoxyribonuclease 2
       5424 POLD1; DNA polymerase delta 1, catalytic subunit
       5425 POLD2; DNA polymerase delta 2, accessory subunit
       10714 POLD3; DNA polymerase delta 3, accessory subunit
       57804 POLD4; DNA polymerase delta 4, accessory subunit
       5426 POLE; DNA polymerase epsilon, catalytic subunit
       5427 POLE2; DNA polymerase epsilon 2, accessory subunit
       54107 POLE3; DNA polymerase epsilon 3, accessory subunit
       56655 POLE4; DNA polymerase epsilon 4, accessory subunit
       5111 PCNA; proliferating cell nuclear antigen
       2237 FEN1; flap structure-specific endonuclease 1
       3978 LIG1; DNA ligase 1
       5423 POLB; DNA polymerase beta
       7515 XRCC1; X-ray repair cross complementing 1
       3980 LIG3; DNA ligase 3
       55775 TDP1; tyrosyl-DNA phosphodiesterase 1
       54840 APTX; aprataxin
       200558 APLF; aprataxin and PNKP like factor
       11284 PNKP; polynucleotide kinase 3'-phosphatase
       3146 HMGB1; high mobility group box 1
       27343 POLL; DNA polymerase lambda
       142 PARP1; poly(ADP-ribose) polymerase 1
       10038 PARP2; poly(ADP-ribose) polymerase 2
       10039 PARP3; poly(ADP-ribose) polymerase family member 3
       143 PARP4; poly(ADP-ribose) polymerase family member 4
       7508 XPC; XPC complex subunit, DNA damage recognition and repair factor
       5887 RAD23B; RAD23 homolog B, nucleotide excision repair protein
       5886 RAD23A; RAD23 homolog A, nucleotide excision repair protein
       1069 CETN2; centrin 2
       9978 RBX1; ring-box 1
       8450 CUL4B; cullin 4B
       8451 CUL4A; cullin 4A
       1642 DDB1; damage specific DNA binding protein 1
       1643 DDB2; damage specific DNA binding protein 2
       5430 POLR2A; RNA polymerase II subunit A
       5431 POLR2B; RNA polymerase II subunit B
       5432 POLR2C; RNA polymerase II subunit C
       5433 POLR2D; RNA polymerase II subunit D
       5434 POLR2E; RNA polymerase II, I and III subunit E
       5435 POLR2F; RNA polymerase II, I and III subunit F
       5436 POLR2G; RNA polymerase II subunit G
       5437 POLR2H; RNA polymerase II, I and III subunit H
       5438 POLR2I; RNA polymerase II subunit I
       5441 POLR2L; RNA polymerase II, I and III subunit L
       5439 POLR2J; RNA polymerase II subunit J
       548644 POLR2J3; RNA polymerase II subunit J3
       246721 POLR2J2; RNA polymerase II subunit J2
       5440 POLR2K; RNA polymerase II, I and III subunit K
       1161 ERCC8; ERCC excision repair 8, CSA ubiquitin ligase complex subunit
       2074 ERCC6; ERCC excision repair 6, chromatin remodeling factor
       57654 UVSSA; UV stimulated scaffold protein A
       2071 ERCC3; ERCC excision repair 3, TFIIH core complex helicase subunit
       2068 ERCC2; ERCC excision repair 2, TFIIH core complex helicase subunit
       2965 GTF2H1; general transcription factor IIH subunit 1
       2966 GTF2H2; general transcription factor IIH subunit 2
       730394 GTF2H2C_2; GTF2H2 family member C, copy 2
       728340 GTF2H2C; GTF2H2 family member C
       2967 GTF2H3; general transcription factor IIH subunit 3
       2968 GTF2H4; general transcription factor IIH subunit 4
       404672 GTF2H5; general transcription factor IIH subunit 5
       1022 CDK7; cyclin dependent kinase 7
       902 CCNH; cyclin H
       4331 MNAT1; MNAT1 component of CDK activating kinase
       6117 RPA1; replication protein A1
       6118 RPA2; replication protein A2
       6119 RPA3; replication protein A3
       29935 RPA4; replication protein A4
       7507 XPA; XPA, DNA damage recognition and repair factor
       2067 ERCC1; ERCC excision repair 1, endonuclease non-catalytic subunit
       2072 ERCC4; ERCC excision repair 4, endonuclease catalytic subunit
       2073 ERCC5; ERCC excision repair 5, endonuclease
       100533467 BIVM-ERCC5; BIVM-ERCC5 readthrough
       64210 MMS19; MMS19 homolog, cytosolic iron-sulfur assembly component
       8452 CUL3; cullin 3
       8065 CUL5; cullin 5
       6921 ELOC; elongin C
       6923 ELOB; elongin B
       51224 ELOA2; elongin A2
       6924 ELOA; elongin A
       4436 MSH2; mutS homolog 2
       4437 MSH3; mutS homolog 3
       2956 MSH6; mutS homolog 6
       4438 MSH4; mutS homolog 4
       4439 MSH5; mutS homolog 5
       5378 PMS1; PMS1 homolog 1, mismatch repair system component
       4292 MLH1; mutL homolog 1
       5395 PMS2; PMS1 homolog 2, mismatch repair system component
       27030 MLH3; mutL homolog 3
       5981 RFC1; replication factor C subunit 1
       5984 RFC4; replication factor C subunit 4
       5982 RFC2; replication factor C subunit 2
       5985 RFC5; replication factor C subunit 5
       5983 RFC3; replication factor C subunit 3
       9156 EXO1; exonuclease 1
       4361 MRE11; MRE11 homolog, double strand break repair nuclease
       10111 RAD50; RAD50 double strand break repair protein
       4683 NBN; nibrin
       672 BRCA1; BRCA1 DNA repair associated
       580 BARD1; BRCA1 associated RING domain 1
       84142 ABRAXAS1; abraxas 1, BRCA1 A complex subunit
       51720 UIMC1; ubiquitin interaction motif containing 1
       29086 BABAM1; BRISC and BRCA1 A complex member 1
       9577 BABAM2; BRISC and BRCA1 A complex member 2
       79184 BRCC3; BRCA1/BRCA2-containing complex subunit 3
       83990 BRIP1; BRCA1 interacting protein C-terminal helicase 1
       11073 TOPBP1; DNA topoisomerase II binding protein 1
       5932 RBBP8; RB binding protein 8, endonuclease
       675 BRCA2; BRCA2 DNA repair associated
       79728 PALB2; partner and localizer of BRCA2
       5888 RAD51; RAD51 recombinase
       5890 RAD51B; RAD51 paralog B
       5889 RAD51C; RAD51 paralog C
       5892 RAD51D; RAD51 paralog D
       7516 XRCC2; X-ray repair cross complementing 2
       7517 XRCC3; X-ray repair cross complementing 3
       11144 DMC1; DNA meiotic recombinase 1
       5893 RAD52; RAD52 homolog, DNA repair protein
       201299 RDM1; RAD52 motif containing 1
       8438 RAD54L; RAD54 like
       23132 RAD54L2; RAD54 like 2
       25788 RAD54B; RAD54 homolog B
       5965 RECQL; RecQ like helicase
       7486 WRN; WRN RecQ like helicase
       641 BLM; BLM RecQ like helicase
       9401 RECQL4; RecQ like helicase 4
       9400 RECQL5; RecQ like helicase 5
       7156 TOP3A; DNA topoisomerase III alpha
       8940 TOP3B; DNA topoisomerase III beta
       80010 RMI1; RecQ mediated genome instability 1
       116028 RMI2; RecQ mediated genome instability 2
       5531 PPP4C; protein phosphatase 4 catalytic subunit
       9989 PPP4R1; protein phosphatase 4 regulatory subunit 1
       151987 PPP4R2; protein phosphatase 4 regulatory subunit 2
       55671 PPP4R3A; protein phosphatase 4 regulatory subunit 3A
       57223 PPP4R3B; protein phosphatase 4 regulatory subunit 3B
       139420 PPP4R3C; protein phosphatase 4 regulatory subunit 3C
       57718 PPP4R4; protein phosphatase 4 regulatory subunit 4
       91056 AP5B1; adaptor related protein complex 5 subunit beta 1
       55745 AP5M1; adaptor related protein complex 5 subunit mu 1
       55317 AP5S1; adaptor related protein complex 5 subunit sigma 1
       9907 AP5Z1; adaptor related protein complex 5 subunit zeta 1
       23137 SMC5; structural maintenance of chromosomes 5
       79677 SMC6; structural maintenance of chromosomes 6
       151354 LRATD1; LRAT domain containing 1
       197370 NSMCE1; NSE1 homolog, SMC5-SMC6 complex component
       286053 NSMCE2; NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase
       56160 NSMCE3; NSE3 homolog, SMC5-SMC6 complex component
       54780 NSMCE4A; NSE4 homolog A, SMC5-SMC6 complex component
       493861 EID3; EP300 interacting inhibitor of differentiation 3
       10388 SYCP2; synaptonemal complex protein 2
       50511 SYCP3; synaptonemal complex protein 3
       146956 EME1; essential meiotic structure-specific endonuclease 1
       197342 EME2; essential meiotic structure-specific endonuclease subunit 2
       55218 EXD2; exonuclease 3'-5' domain containing 2
       164045 HFM1; helicase for meiosis 1
       80198 MUS81; MUS81 structure-specific endonuclease subunit
       7979 SEM1; SEM1 26S proteasome complex subunit
       23626 SPO11; SPO11 initiator of meiotic double stranded breaks
       548593 SLX1A; SLX1 homolog A, structure-specific endonuclease subunit
       79008 SLX1B; SLX1 homolog B, structure-specific endonuclease subunit
       84464 SLX4; SLX4 structure-specific endonuclease subunit
       348654 GEN1; GEN1 Holliday junction 5' flap endonuclease
       80208 SPG11; SPG11 vesicle trafficking associated, spatacsin
       23503 ZFYVE26; zinc finger FYVE-type containing 26
       10635 RAD51AP1; RAD51 associated protein 1
       10933 MORF4L1; mortality factor 4 like 1
       254528 MEIOB; meiosis specific with OB-fold
       84690 SPATA22; spermatogenesis associated 22
       25939 SAMHD1; SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
       63979 FIGNL1; fidgetin like 1
       23514 SPIDR; scaffold protein involved in DNA repair
       157638 LRATD2; LRAT domain containing 2
       221927 BRAT1; BRCA1 associated ATM activator 1
       755 CFAP410; cilia and flagella associated protein 410
       2547 XRCC6; X-ray repair cross complementing 6
       7520 XRCC5; X-ray repair cross complementing 5
       5591 PRKDC; protein kinase, DNA-activated, catalytic subunit
       3981 LIG4; DNA ligase 4
       7518 XRCC4; X-ray repair cross complementing 4
       79840 NHEJ1; non-homologous end joining factor 1
       27434 POLM; DNA polymerase mu
       1791 DNTT; DNA nucleotidylexotransferase
       64421 DCLRE1C; DNA cross-link repair 1C
       51567 TDP2; tyrosyl-DNA phosphodiesterase 2
       23347 SMCHD1; structural maintenance of chromosomes flexible hinge domain containing 1
       139221 PWWP3B; PWWP domain containing 3B
       84939 PWWP3A; PWWP domain containing 3A, DNA repair factor
       2175 FANCA; FA complementation group A
       2187 FANCB; FA complementation group B
       2176 FANCC; FA complementation group C
       2178 FANCE; FA complementation group E
       2188 FANCF; FA complementation group F
       2189 FANCG; FA complementation group G
       55120 FANCL; FA complementation group L
       57697 FANCM; FA complementation group M
       91442 FAAP24; FA core complex associated protein 24
       80233 FAAP100; FA core complex associated protein 100
       3280 HES1; hes family bHLH transcription factor 1
       378708 CENPS; centromere protein S
       100526739 CENPS-CORT; CENPS-CORT readthrough
       201254 CENPX; centromere protein X
       29089 UBE2T; ubiquitin conjugating enzyme E2 T
       2177 FANCD2; FA complementation group D2
       55215 FANCI; FA complementation group I
       22909 FAN1; FANCD2 and FANCI associated nuclease 1
       9894 TELO2; telomere maintenance 2
       7398 USP1; ubiquitin specific peptidase 1
       57599 WDR48; WD repeat domain 48
       5537 PPP6C; protein phosphatase 6 catalytic subunit
       22870 PPP6R1; protein phosphatase 6 regulatory subunit 1
       9701 PPP6R2; protein phosphatase 6 regulatory subunit 2
       55291 PPP6R3; protein phosphatase 6 regulatory subunit 3
       23243 ANKRD28; ankyrin repeat domain 28
       91526 ANKRD44; ankyrin repeat domain 44
       283373 ANKRD52; ankyrin repeat domain 52
       9025 RNF8; ring finger protein 8
       165918 RNF168; ring finger protein 168
       254225 RNF169; ring finger protein 169
       8924 HERC2; HECT and RLD domain containing E3 ubiquitin protein ligase 2
       55135 WRAP53; WD repeat containing antisense to TP53
       286262 TPRN; taperin
       5429 POLH; DNA polymerase eta
       11201 POLI; DNA polymerase iota
       51426 POLK; DNA polymerase kappa
       51455 REV1; REV1 DNA directed polymerase
       5980 REV3L; REV3 like, DNA directed polymerase zeta catalytic subunit
       353497 POLN; DNA polymerase nu
       7319 UBE2A; ubiquitin conjugating enzyme E2 A
       7320 UBE2B; ubiquitin conjugating enzyme E2 B
       56852 RAD18; RAD18 E3 ubiquitin protein ligase
       6596 HLTF; helicase like transcription factor
       7335 UBE2V1; ubiquitin conjugating enzyme E2 V1
       7336 UBE2V2; ubiquitin conjugating enzyme E2 V2
       389898 UBE2NL; ubiquitin conjugating enzyme E2 N like (gene/pseudogene)
       7334 UBE2N; ubiquitin conjugating enzyme E2 N
       79624 ARMT1; acidic residue methyltransferase 1
       83932 SPRTN; SprT-like N-terminal domain
       5883 RAD9A; RAD9 checkpoint clamp component A
       144715 RAD9B; RAD9 checkpoint clamp component B
       3364 HUS1; HUS1 checkpoint clamp component
       135458 HUS1B; HUS1 checkpoint clamp component B
       5810 RAD1; RAD1 checkpoint DNA exonuclease
       5884 RAD17; RAD17 checkpoint clamp loader component
       8914 TIMELESS; timeless circadian regulator
       54962 TIPIN; TIMELESS interacting protein
       9675 TTI1; TELO2 interacting protein 1
       80185 TTI2; TELO2 interacting protein 2
       7917 BAG6; BAG cochaperone 6
       8266 UBL4A; ubiquitin like 4A
       164153 UBL4B; ubiquitin like 4B
       51608 GET4; guided entry of tail-anchored proteins factor 4
       545 ATR; ATR serine/threonine kinase
       84126 ATRIP; ATR interacting protein
       472 ATM; ATM serine/threonine kinase
       7157 TP53; tumor protein p53
       1111 CHEK1; checkpoint kinase 1
       11200 CHEK2; checkpoint kinase 2
       993 CDC25A; cell division cycle 25A
       994 CDC25B; cell division cycle 25B
       995 CDC25C; cell division cycle 25C
       7534 YWHAZ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
       7529 YWHAB; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
       10971 YWHAQ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
       7533 YWHAH; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
       7532 YWHAG; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
       7531 YWHAE; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
       89797 NAV2; neuron navigator 2
       7465 WEE1; WEE1 G2 checkpoint kinase
       494551 WEE2; WEE2 oocyte meiosis inhibiting kinase
       5187 PER1; period circadian regulator 1
       8864 PER2; period circadian regulator 2
       8863 PER3; period circadian regulator 3
       9656 MDC1; mediator of DNA damage checkpoint 1
       5358 PLS3; plastin 3
       64782 AEN; apoptosis enhancing nuclease
       1263 PLK3; polo like kinase 3
       126520 PLK5; polo like kinase 5 (inactive)
       341676 NEK5; NIMA related kinase 5
       4750 NEK1; NIMA related kinase 1
       6787 NEK4; NIMA related kinase 4
       152110 NEK10; NIMA related kinase 10
       79858 NEK11; NIMA related kinase 11
       29980 DONSON; DNA replication fork stabilization factor DONSON
       163782 KANK4; KN motif and ankyrin repeat domains 4
       23189 KANK1; KN motif and ankyrin repeat domains 1
       256949 KANK3; KN motif and ankyrin repeat domains 3
       25959 KANK2; KN motif and ankyrin repeat domains 2
       100144748 KLLN; killin, p53 regulated DNA replication inhibitor
       91607 SLFN11; schlafen family member 11
       10721 POLQ; DNA polymerase theta
       10514 MYBBP1A; MYB binding protein 1a
       201973 PRIMPOL; primase and DNA directed polymerase
       11277 TREX1; three prime repair exonuclease 1
       11219 TREX2; three prime repair exonuclease 2
       9937 DCLRE1A; DNA cross-link repair 1A
       64858 DCLRE1B; DNA cross-link repair 1B
       64789 EXO5; exonuclease 5
       284131 ENDOV; endonuclease V
       126549 ANKLE1; ankyrin repeat and LEM domain containing 1
       113510 HELQ; helicase, POLQ like
       375748 ERCC6L2; ERCC excision repair 6 like 2
       27339 PRPF19; pre-mRNA processing factor 19
       988 CDC5L; cell division cycle 5 like
       10286 BCAS2; BCAS2 pre-mRNA processing factor
       5356 PLRG1; pleiotropic regulator 1
       55270 NUDT15; nudix hydrolase 15
       4521 NUDT1; nudix hydrolase 1
       79873 NUDT18; nudix hydrolase 18
       1854 DUT; deoxyuridine triphosphatase
       6240 RRM1; ribonucleotide reductase catalytic subunit M1
       50484 RRM2B; ribonucleotide reductase regulatory TP53 inducible subunit M2B
       6241 RRM2; ribonucleotide reductase regulatory subunit M2
       6742 SSBP1; single stranded DNA binding protein 1
K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
K10859 ALKBH2; DNA oxidative demethylase [EC:1.14.11.33]
K10860 ALKBH3; mRNA N1-methyladenine demethylase [EC:1.14.11.54]
K18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:3.6.4.12]
K02295 CRY; cryptochrome
K02295 CRY; cryptochrome
K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
K10861 UDG2; uracil-DNA glycosylase 2 [EC:3.2.2.-]
K20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]
K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]
K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
K10801 MBD4; methyl-CpG-binding domain protein 4 [EC:3.2.2.-]
K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
K10567 NEIL1; endonuclease VIII-like 1 [EC:3.2.2.- 4.2.99.18]
K10568 NEIL2; endonuclease VIII-like 2 [EC:3.2.2.- 4.2.99.18]
K10569 NEIL3; endonuclease VIII-like 3
K10773 NTH; endonuclease III [EC:4.2.99.18]
K10771 APEX1; AP endonuclease 1 [EC:4.2.99.18]
K10772 APEX2; AP endonuclease 2 [EC:4.2.99.18]
K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
K02328 POLD2; DNA polymerase delta subunit 2
K03504 POLD3; DNA polymerase delta subunit 3
K03505 POLD4; DNA polymerase delta subunit 4
K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
K04802 PCNA; proliferating cell nuclear antigen
K04799 FEN1; flap endonuclease-1 [EC:3.-.-.-]
K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
K10803 XRCC1; DNA-repair protein XRCC1
K10776 LIG3; DNA ligase 3 [EC:6.5.1.1]
K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]
K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
K13295 APLF; aprataxin and PNK-like factor [EC:4.2.99.18]
K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78]
K10802 HMGB1; high mobility group protein B1
K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]
K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
K10838 XPC; xeroderma pigmentosum group C-complementing protein
K10839 RAD23; UV excision repair protein RAD23
K10839 RAD23; UV excision repair protein RAD23
K10840 CETN2; centrin-2
K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
K10609 CUL4; cullin 4
K10609 CUL4; cullin 4
K10610 DDB1; DNA damage-binding protein 1
K10140 DDB2; DNA damage-binding protein 2
K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3
K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
K03013 RPB5; DNA-directed RNA polymerases I, II, and III subunit RPABC1
K03014 RPB6; DNA-directed RNA polymerases I, II, and III subunit RPABC2
K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
K03016 RPB8; DNA-directed RNA polymerases I, II, and III subunit RPABC3
K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9
K03007 RPB10; DNA-directed RNA polymerases I, II, and III subunit RPABC5
K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
K03009 RPB12; DNA-directed RNA polymerases I, II, and III subunit RPABC4
K10570 ERCC8; DNA excision repair protein ERCC-8
K10841 ERCC6; DNA excision repair protein ERCC-6
K23720 UVSSA; UV-stimulated scaffold protein A
K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:3.6.4.12]
K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:3.6.4.12]
K03141 TFIIH1; transcription initiation factor TFIIH subunit 1
K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
K03143 TFIIH3; transcription initiation factor TFIIH subunit 3
K03144 TFIIH4; transcription initiation factor TFIIH subunit 4
K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit
K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
K06634 CCNH; cyclin H
K10842 MNAT1; CDK-activating kinase assembly factor MAT1
K07466 RFA1; replication factor A1
K10739 RFA2; replication factor A2
K10740 RPA3; replication factor A3
K10741 RPA4; replication factor A4
K10847 XPA; DNA-repair protein complementing XP-A cells
K10849 ERCC1; DNA excision repair protein ERCC-1
K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
K10846 ERCC5; DNA excision repair protein ERCC-5
K10846 ERCC5; DNA excision repair protein ERCC-5
K15075 MET18; DNA repair/transcription protein MET18/MMS19
K03869 CUL3; cullin 3
K10612 CUL5; cullin 5
K03872 ELOC; elongin-C
K03873 ELOB; elongin-B
K15076 ELOA; elongin-A
K15076 ELOA; elongin-A
K08735 MSH2; DNA mismatch repair protein MSH2
K08736 MSH3; DNA mismatch repair protein MSH3
K08737 MSH6; DNA mismatch repair protein MSH6
K08740 MSH4; DNA mismatch repair protein MSH4
K08741 MSH5; DNA mismatch repair protein MSH5
K10864 PMS1; DNA mismatch repair protein PMS1
K08734 MLH1; DNA mismatch repair protein MLH1
K10858 PMS2; DNA mismatch repair protein PMS2
K08739 MLH3; DNA mismatch repair protein MLH3
K10754 RFC1; replication factor C subunit 1
K10755 RFC2_4; replication factor C subunit 2/4
K10755 RFC2_4; replication factor C subunit 2/4
K10756 RFC3_5; replication factor C subunit 3/5
K10756 RFC3_5; replication factor C subunit 3/5
K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
K10865 MRE11; double-strand break repair protein MRE11
K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
K10867 NBN; nibrin
K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
K10683 BARD1; BRCA1-associated RING domain protein 1
K20774 FAM175A; BRCA1-A complex subunit Abraxas
K20775 UIMC1; BRCA1-A complex subunit RAP80
K20776 BABAM; BRISC and BRCA1-A complex member 1
K12173 BRE; BRCA1-A complex subunit BRE
K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
K15362 BRIP1; fanconi anemia group J protein [EC:3.6.4.12]
K10728 TOPBP1; topoisomerase (DNA) II binding protein 1
K20773 RBBP8; DNA endonuclease RBBP8 [EC:3.1.-.-]
K08775 BRCA2; breast cancer 2 susceptibility protein
K10897 PALB2; partner and localizer of BRCA2
K04482 RAD51; DNA repair protein RAD51
K10869 RAD51L1; RAD51-like protein 1
K10870 RAD51L2; RAD51-like protein 2
K10871 RAD51L3; RAD51-like protein 3
K10879 XRCC2; DNA-repair protein XRCC2
K10880 XRCC3; DNA-repair protein XRCC3
K10872 DMC1; meiotic recombination protein DMC1
K10873 RAD52; DNA repair and recombination protein RAD52
K10874 RDM1; RAD52 motif-containing protein 1
K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:3.6.4.-]
K10876 RAD54L2; RAD54-like protein 2 [EC:3.6.4.12]
K10877 RAD54B; DNA repair and recombination protein RAD54B [EC:3.6.4.-]
K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:3.6.4.12]
K10900 WRN; werner syndrome ATP-dependent helicase [EC:3.6.4.12]
K10901 BLM; bloom syndrome protein [EC:3.6.4.12]
K10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:3.6.4.12]
K10902 RECQL5; ATP-dependent DNA helicase Q5 [EC:3.6.4.12]
K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
K10990 RMI1; RecQ-mediated genome instability protein 1
K15365 RMI2; RecQ-mediated genome instability protein 2
K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
K15424 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1
K15425 PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2
K17491 SMEK; protein phosphatase 4 regulatory subunit 3
K17491 SMEK; protein phosphatase 4 regulatory subunit 3
K17491 SMEK; protein phosphatase 4 regulatory subunit 3
K15426 PPP4R4; serine/threonine-protein phosphatase 4 regulatory subunit 4
K19022 AP5B1; AP-5 complex subunit beta-1
K19023 AP5M1; AP-5 complex subunit mu-1
K19024 AP5S1; AP-5 complex subunit sigma-1
K19025 AP5Z1; AP-5 complex subunit zeta-1
K22803 SMC5; structural maintenance of chromosomes protein 5
K22804 SMC6; structural maintenance of chromosomes protein 6
K22805 FAM84A; protein FAM84A
K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
K22823 NSMCE3; non-structural maintenance of chromosomes element 3
K22825 NSMCE4; non-structural maintenance of chromosomes element 4
K22826 EID3; EP300-interacting inhibitor of differentiation 3
K19529 SYCP2; synaptonemal complex protein 2
K19528 SYCP3; synaptonemal complex protein 3
K10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]
K10883 EME2; crossover junction endonuclease EME2
K20777 EXD2; exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1]
K15271 HFM1; ATP-dependent DNA helicase HFM1/MER3 [EC:3.6.4.12]
K08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]
K10881 SHFM1; 26 proteasome complex subunit DSS1
K10878 SPO11; meiotic recombination protein SPO11
K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]
K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]
K10484 BTBD12; structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
K15338 GEN1; flap endonuclease GEN [EC:3.1.-.-]
K19026 SPG11; spatacsin
K19027 ZFYVE26; zinc finger FYVE domain-containing protein 26
K20778 RAD51AP1; RAD51-associated protein 1
K11339 MORF4L1; mortality factor 4-like protein 1
K22420 MEIOB; meiosis-specific with OB domain-containing protein [EC:3.1.-.-]
K22421 SPATA22; spermatogenesis-associated protein 22
K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
K22766 FIGNL1; fidgetin-like protein 1 [EC:3.6.4.-]
K22806 SPIDR; DNA repair-scaffolding protein
K22810 FAM84B; protein FAM84B
K23112 BRAT1; BRCA1-associated ATM activator 1
K23456 CFAP410; cilla- and flagella-associated protein
K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1
K10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2
K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
K10777 LIG4; DNA ligase 4 [EC:6.5.1.1]
K10886 XRCC4; DNA-repair protein XRCC4
K10980 NHEJ1; non-homologous end-joining factor 1
K03513 POLM; DNA polymerase mu [EC:2.7.7.7]
K00977 DNTT; DNA nucleotidylexotransferase [EC:2.7.7.31]
K10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-]
K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]
K23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1
K23386 PWWP3; PWWP domain-containing DNA repair factor 3
K23386 PWWP3; PWWP domain-containing DNA repair factor 3
K10888 FANCA; fanconi anemia group A protein
K10889 FANCB; fanconi anemia group B protein
K10890 FANCC; fanconi anemia group C protein
K10892 FANCE; fanconi anemia group E protein
K10893 FANCF; fanconi anemia group F protein
K10894 FANCG; fanconi anemia group G protein
K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]
K10896 FANCM; fanconi anemia group M protein
K10898 FAAP24; fanconi anemia-associated protein
K10993 FAAP100; fanconi anemia core complex 100 kDa subunit
K06054 HES1; hairy and enhancer of split 1
K11511 APITD1; centromere protein S
K11511 APITD1; centromere protein S
K15360 STRA13; centromere protein X
K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]
K10891 FANCD2; fanconi anemia group D2 protein
K10895 FANCI; fanconi anemia group I protein
K15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]
K11137 TELO2; telomere length regulation protein
K11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]
K15361 WDR48; WD repeat-containing protein 48
K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]
K15499 PPP6R1; serine/threonine-protein phosphatase 6 regulatory subunit 1
K15500 PPP6R2; serine/threonine-protein phosphatase 6 regulatory subunit 2
K15501 PPP6R3; serine/threonine-protein phosphatase 6 regulatory subunit 3
K15502 ANKRD28; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A
K15503 ANKRD44; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B
K15504 ANKRD52; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C
K10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]
K20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31]
K20805 RNF169; E3 ubiquitin-protein ligase RNF169 [EC:2.3.2.31]
K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]
K23314 WRAP53; telomerase Cajal body protein 1
K24164 TPRN; taperin
K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
K03510 POLI; DNA polymerase iota [EC:2.7.7.7]
K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]
K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]
K16618 POLN; DNA polymerase nu [EC:2.7.7.7]
K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
K10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]
K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
K15711 SMARCA3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:3.6.4.- 2.3.2.27]
K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
K23114 ARMT1; protein-glutamate O-methyltransferase [EC:2.1.1.-]
K24051 SPRTN; SprT-like domain-contaning protein Spartan
K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]
K10995 RAD9B; cell cycle checkpoint control protein RAD9B
K10903 HUS1; HUS1 checkpoint protein
K10996 HUS1B; checkpoint protein HUS1B
K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
K06662 HRAD17; cell cycle checkpoint protein
K03155 TIMELESS; timeless
K10904 TIPIN; TIMELESS-interacting protein
K20403 TTI1; TELO2-interacting protein 1
K23115 TTI2; TELO2-interacting protein 2
K23390 BAG6; large proline-rich protein BAG6
K23388 UBL4; ubiquitin-like protein 4
K23388 UBL4; ubiquitin-like protein 4
K23387 GET4; golgi to ER traffic protein 4
K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
K10905 ATRIP; ATR interacting protein
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K04451 TP53; tumor protein p53
K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
K06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
K05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K16198 YWHAG_H; 14-3-3 protein gamma/eta
K06630 YWHAE; 14-3-3 protein epsilon
K19483 NAV2; neuron navigator 2 [EC:3.6.4.12]
K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
K21944 PER1; period circadian protein 1
K02633 PER2; period circadian protein 2
K21945 PER3; period circadian protein 3
K20780 MDC1; mediator of DNA damage checkpoint protein 1
K17336 PLS3; plastin-3
K18340 AEN; apoptosis-enhancing nuclease [EC:3.1.-.-]
K08862 PLK3; polo-like kinase 3 [EC:2.7.11.21]
K19596 PLK5; inactive serine/threonine-protein kinase PLK5
K08857 NEK1_4_5; NIMA (never in mitosis gene a)-related kinase 1/4/5 [EC:2.7.11.1]
K08857 NEK1_4_5; NIMA (never in mitosis gene a)-related kinase 1/4/5 [EC:2.7.11.1]
K08857 NEK1_4_5; NIMA (never in mitosis gene a)-related kinase 1/4/5 [EC:2.7.11.1]
K20879 NEK10; NIMA (never in mitosis gene a)-related kinase 10 [EC:2.7.11.1]
K20880 NEK11; NIMA (never in mitosis gene a)-related kinase 11 [EC:2.7.11.1]
K22422 DONSON; protein downstream neighbor of Son
K22808 KANK; KN motif and ankyrin repeat domain-containing protein
K22808 KANK; KN motif and ankyrin repeat domain-containing protein
K22808 KANK; KN motif and ankyrin repeat domain-containing protein
K22808 KANK; KN motif and ankyrin repeat domain-containing protein
K23389 KLLN; killin
K24458 SLFN11; schlafen family member 11 [EC:3.6.-.-]
K02349 POLQ; DNA polymerase theta [EC:2.7.7.7]
K02331 POL5; DNA polymerase phi [EC:2.7.7.7]
K22761 PRIMPOL; DNA-directed primase/polymerase protein [EC:2.7.7.102 2.7.7.7]
K10790 TREX1; three prime repair exonuclease 1 [EC:3.1.11.2]
K10791 TREX2; three prime repair exonuclease 2 [EC:3.1.11.2]
K15340 DCLRE1A; DNA cross-link repair 1A protein
K15341 DCLRE1B; DNA cross-link repair 1B protein [EC:3.1.-.-]
K17815 EXO5; exonuclease V [EC:3.1.-.-]
K21813 ENDOV; endonuclease V [EC:3.1.26.-]
K21411 ANKLE1; ankyrin repeat and LEM domain-containing protein 1
K19178 HELQ; POLQ-like helicase [EC:3.6.4.12]
K20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:3.6.4.-]
K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1
K12861 BCAS2; pre-mRNA-splicing factor SPF27
K12862 PLRG1; pleiotropic regulator 1
K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
K17816 NUDT1; 8-oxo-dGTP diphosphatase / 2-hydroxy-dATP diphosphatase [EC:3.6.1.55 3.6.1.56]
K17817 NUDT18; 8-oxo-dGDP phosphatase [EC:3.6.1.58]
K01520 dut; dUTP pyrophosphatase [EC:3.6.1.23]
K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K03111 ssb; single-strand DNA-binding protein
     03029 Mitochondrial biogenesis [BR:hsa03029]
 
   09183 Protein families: signaling and cellular processes
 
   09184 RNA family
 
 09190 Not Included in Pathway or Brite

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: January 18, 2021