KEGG Orthology (KO) - Homo sapiens (human)

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     KO
 09100 Metabolism
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
   09131 Membrane transport
 
   09132 Signal transduction
     02020 Two-component system
     04010 MAPK signaling pathway [PATH:hsa04010]
     04013 MAPK signaling pathway - fly
     04016 MAPK signaling pathway - plant
     04011 MAPK signaling pathway - yeast
     04012 ErbB signaling pathway [PATH:hsa04012]
     04014 Ras signaling pathway [PATH:hsa04014]
     04015 Rap1 signaling pathway [PATH:hsa04015]
     04310 Wnt signaling pathway [PATH:hsa04310]
     04330 Notch signaling pathway [PATH:hsa04330]
     04340 Hedgehog signaling pathway [PATH:hsa04340]
     04341 Hedgehog signaling pathway - fly
     04350 TGF-beta signaling pathway [PATH:hsa04350]
     04390 Hippo signaling pathway [PATH:hsa04390]
     04391 Hippo signaling pathway - fly
     04392 Hippo signaling pathway - multiple species [PATH:hsa04392]
     04370 VEGF signaling pathway [PATH:hsa04370]
     04371 Apelin signaling pathway [PATH:hsa04371]
     04630 JAK-STAT signaling pathway [PATH:hsa04630]
     04064 NF-kappa B signaling pathway [PATH:hsa04064]
     04668 TNF signaling pathway [PATH:hsa04668]
     04066 HIF-1 signaling pathway [PATH:hsa04066]
     04068 FoxO signaling pathway [PATH:hsa04068]
     04020 Calcium signaling pathway [PATH:hsa04020]
     04070 Phosphatidylinositol signaling system [PATH:hsa04070]
     04072 Phospholipase D signaling pathway [PATH:hsa04072]
     04071 Sphingolipid signaling pathway [PATH:hsa04071]
     04024 cAMP signaling pathway [PATH:hsa04024]
     04022 cGMP-PKG signaling pathway [PATH:hsa04022]
     04151 PI3K-Akt signaling pathway [PATH:hsa04151]
     04152 AMPK signaling pathway [PATH:hsa04152]
       6885 MAP3K7; mitogen-activated protein kinase kinase kinase 7
       6794 STK11; serine/threonine kinase 11
       51719 CAB39; calcium binding protein 39
       81617 CAB39L; calcium binding protein 39 like
       92335 STRADA; STE20 related adaptor alpha
       55437 STRADB; STE20 related adaptor beta
       3952 LEP; leptin
       3953 LEPR; leptin receptor
       10645 CAMKK2; calcium/calmodulin dependent protein kinase kinase 2
       148 ADRA1A; adrenoceptor alpha 1A
       9370 ADIPOQ; adiponectin, C1Q and collagen domain containing
       51094 ADIPOR1; adiponectin receptor 1
       79602 ADIPOR2; adiponectin receptor 2
       5562 PRKAA1; protein kinase AMP-activated catalytic subunit alpha 1
       5563 PRKAA2; protein kinase AMP-activated catalytic subunit alpha 2
       5564 PRKAB1; protein kinase AMP-activated non-catalytic subunit beta 1
       5565 PRKAB2; protein kinase AMP-activated non-catalytic subunit beta 2
       5571 PRKAG1; protein kinase AMP-activated non-catalytic subunit gamma 1
       53632 PRKAG3; protein kinase AMP-activated non-catalytic subunit gamma 3
       51422 PRKAG2; protein kinase AMP-activated non-catalytic subunit gamma 2
       5207 PFKFB1; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
       5208 PFKFB2; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
       5209 PFKFB3; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
       5210 PFKFB4; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
       2203 FBP1; fructose-bisphosphatase 1
       8789 FBP2; fructose-bisphosphatase 2
       5213 PFKM; phosphofructokinase, muscle
       5214 PFKP; phosphofructokinase, platelet
       5211 PFKL; phosphofructokinase, liver type
       3172 HNF4A; hepatocyte nuclear factor 4 alpha
       2538 G6PC1; glucose-6-phosphatase catalytic subunit 1
       57818 G6PC2; glucose-6-phosphatase catalytic subunit 2
       92579 G6PC3; glucose-6-phosphatase catalytic subunit 3
       5105 PCK1; phosphoenolpyruvate carboxykinase 1
       5106 PCK2; phosphoenolpyruvate carboxykinase 2, mitochondrial
       200186 CRTC2; CREB regulated transcription coactivator 2
       1385 CREB1; cAMP responsive element binding protein 1
       10488 CREB3; cAMP responsive element binding protein 3
       90993 CREB3L1; cAMP responsive element binding protein 3 like 1
       64764 CREB3L2; cAMP responsive element binding protein 3 like 2
       84699 CREB3L3; cAMP responsive element binding protein 3 like 3
       148327 CREB3L4; cAMP responsive element binding protein 3 like 4
       9586 CREB5; cAMP responsive element binding protein 5
       10891 PPARGC1A; PPARG coactivator 1 alpha
       1994 ELAVL1; ELAV like RNA binding protein 1
       595 CCND1; cyclin D1
       890 CCNA2; cyclin A2
       8900 CCNA1; cyclin A1
       29904 EEF2K; eukaryotic elongation factor 2 kinase
       1938 EEF2; eukaryotic translation elongation factor 2
       2308 FOXO1; forkhead box O1
       2309 FOXO3; forkhead box O3
       23411 SIRT1; sirtuin 1
       6517 SLC2A4; solute carrier family 2 member 4
       2998 GYS2; glycogen synthase 2
       2997 GYS1; glycogen synthase 1
       3991 LIPE; lipase E, hormone sensitive type
       3156 HMGCR; 3-hydroxy-3-methylglutaryl-CoA reductase
       6720 SREBF1; sterol regulatory element binding transcription factor 1
       2194 FASN; fatty acid synthase
       31 ACACA; acetyl-CoA carboxylase alpha
       6319 SCD; stearoyl-CoA desaturase
       79966 SCD5; stearoyl-CoA desaturase 5
       32 ACACB; acetyl-CoA carboxylase beta
       23417 MLYCD; malonyl-CoA decarboxylase
       1374 CPT1A; carnitine palmitoyltransferase 1A
       1375 CPT1B; carnitine palmitoyltransferase 1B
       126129 CPT1C; carnitine palmitoyltransferase 1C
       5515 PPP2CA; protein phosphatase 2 catalytic subunit alpha
       5516 PPP2CB; protein phosphatase 2 catalytic subunit beta
       5519 PPP2R1B; protein phosphatase 2 scaffold subunit Abeta
       5518 PPP2R1A; protein phosphatase 2 scaffold subunit Aalpha
       5520 PPP2R2A; protein phosphatase 2 regulatory subunit Balpha
       5521 PPP2R2B; protein phosphatase 2 regulatory subunit Bbeta
       5522 PPP2R2C; protein phosphatase 2 regulatory subunit Bgamma
       55844 PPP2R2D; protein phosphatase 2 regulatory subunit Bdelta
       28227 PPP2R3B; protein phosphatase 2 regulatory subunit B''beta
       55012 PPP2R3C; protein phosphatase 2 regulatory subunit B''gamma
       5523 PPP2R3A; protein phosphatase 2 regulatory subunit B''alpha
       5526 PPP2R5B; protein phosphatase 2 regulatory subunit B'beta
       5527 PPP2R5C; protein phosphatase 2 regulatory subunit B'gamma
       5528 PPP2R5D; protein phosphatase 2 regulatory subunit B'delta
       5529 PPP2R5E; protein phosphatase 2 regulatory subunit B'epsilon
       5525 PPP2R5A; protein phosphatase 2 regulatory subunit B'alpha
       23216 TBC1D1; TBC1 domain family member 1
       5862 RAB2A; RAB2A, member RAS oncogene family
       4218 RAB8A; RAB8A, member RAS oncogene family
       10890 RAB10; RAB10, member RAS oncogene family
       9230 RAB11B; RAB11B, member RAS oncogene family
       51552 RAB14; RAB14, member RAS oncogene family
       1080 CFTR; CF transmembrane conductance regulator
       948 CD36; CD36 molecule
       3479 IGF1; insulin like growth factor 1
       3480 IGF1R; insulin like growth factor 1 receptor
       3630 INS; insulin
       3643 INSR; insulin receptor
       3667 IRS1; insulin receptor substrate 1
       8660 IRS2; insulin receptor substrate 2
       8471 IRS4; insulin receptor substrate 4
       5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
       5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
       8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
       5170 PDPK1; 3-phosphoinositide dependent protein kinase 1
       207 AKT1; AKT serine/threonine kinase 1
       208 AKT2; AKT serine/threonine kinase 2
       10000 AKT3; AKT serine/threonine kinase 3
       7249 TSC2; TSC complex subunit 2
       7248 TSC1; TSC complex subunit 1
       6009 RHEB; Ras homolog, mTORC1 binding
       2475 MTOR; mechanistic target of rapamycin kinase
       57521 RPTOR; regulatory associated protein of MTOR complex 1
       84335 AKT1S1; AKT1 substrate 1
       6198 RPS6KB1; ribosomal protein S6 kinase B1
       6199 RPS6KB2; ribosomal protein S6 kinase B2
       1978 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
       5468 PPARG; peroxisome proliferator activated receptor gamma
       8408 ULK1; unc-51 like autophagy activating kinase 1
K04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K07298 STK11; serine/threonine-protein kinase 11 [EC:2.7.11.1]
K08272 CAB39; calcium binding protein 39
K08272 CAB39; calcium binding protein 39
K08271 STRADA; STE20-related kinase adapter protein alpha
K17532 STRADB; STE20-related kinase adapter protein beta
K05424 LEP; leptin
K05062 LEPR; leptin receptor
K07359 CAMKK2; calcium/calmodulin-dependent protein kinase kinase 2 [EC:2.7.11.17]
K04135 ADRA1A; adrenergic receptor alpha-1A
K07296 ADIPOQ; adiponectin
K07297 ADIPOR; adiponectin receptor
K07297 ADIPOR; adiponectin receptor
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K19028 PFKFB1; 6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 1 [EC:2.7.1.105 3.1.3.46]
K19029 PFKFB2; 6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 2 [EC:2.7.1.105 3.1.3.46]
K01103 PFKFB3; 6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 3 [EC:2.7.1.105 3.1.3.46]
K19030 PFKFB4; 6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 4 [EC:2.7.1.105 3.1.3.46]
K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
K07292 NR2A1; hepatocyte nuclear factor 4-alpha
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K16333 CRTC2; CREB-regulated transcription coactivator 2
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5; cyclic AMP-responsive element-binding protein 5
K07202 PPARGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
K13088 ELAVL1; ELAV-like protein 1
K04503 CCND1; G1/S-specific cyclin-D1
K06627 CCNA; cyclin-A
K06627 CCNA; cyclin-A
K08292 EEF2K; elongation factor 2 kinase [EC:2.7.11.20]
K03234 EEF2; elongation factor 2
K07201 FOXO1; forkhead box protein O1
K09408 FOXO3; forkhead box protein O3
K11411 SIRT1; NAD+-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K07191 SLC2A4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
K00693 GYS; glycogen synthase [EC:2.4.1.11]
K00693 GYS; glycogen synthase [EC:2.4.1.11]
K07188 LIPE; hormone-sensitive lipase [EC:3.1.1.79]
K00021 HMGCR; hydroxymethylglutaryl-CoA reductase (NADPH) [EC:1.1.1.34]
K07197 SREBP1; sterol regulatory element-binding transcription factor 1
K00665 FASN; fatty acid synthase, animal type [EC:2.3.1.85]
K11262 ACACA; acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
K00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
K01946 ACACB; acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K01578 MLYCD; malonyl-CoA decarboxylase [EC:4.1.1.9]
K08765 CPT1A; carnitine O-palmitoyltransferase 1, liver isoform [EC:2.3.1.21]
K19523 CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform [EC:2.3.1.21]
K19524 CPT1C; carnitine O-palmitoyltransferase 1, brain isoform [EC:2.3.1.21]
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K18341 TBC1D1; TBC1 domain family member 1
K07877 RAB2A; Ras-related protein Rab-2A
K07901 RAB8A; Ras-related protein Rab-8A
K07903 RAB10; Ras-related protein Rab-10
K07905 RAB11B; Ras-related protein Rab-11B
K07881 RAB14; Ras-related protein Rab-14
K05031 CFTR; cystic fibrosis transmembrane conductance regulator [EC:5.6.1.6]
K06259 CD36; CD36 antigen
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K04526 INS; insulin
K04527 INSR; insulin receptor [EC:2.7.10.1]
K16172 IRS1; insulin receptor substrate 1
K07187 IRS2; insulin receptor substrate 2
K17446 IRS4; insulin receptor substrate 4
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07207 TSC2; tuberous sclerosis 2
K07206 TSC1; tuberous sclerosis 1
K07208 RHEB; Ras homolog enriched in brain
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07204 RAPTOR; regulatory associated protein of mTOR
K16184 AKT1S1; proline-rich AKT1 substrate 1
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K08530 NR1C3; peroxisome proliferator-activated receptor gamma
K21357 ULK1; serine/threonine-protein kinase ULK1 [EC:2.7.11.1]
     04150 mTOR signaling pathway [PATH:hsa04150]
     04075 Plant hormone signal transduction
 
   09133 Signaling molecules and interaction
 
 09140 Cellular Processes
 
 09150 Organismal Systems
 
   09151 Immune system
 
   09152 Endocrine system
     04911 Insulin secretion [PATH:hsa04911]
     04910 Insulin signaling pathway [PATH:hsa04910]
     04922 Glucagon signaling pathway [PATH:hsa04922]
     04923 Regulation of lipolysis in adipocytes [PATH:hsa04923]
     04920 Adipocytokine signaling pathway [PATH:hsa04920]
       7124 TNF; tumor necrosis factor
       7132 TNFRSF1A; TNF receptor superfamily member 1A
       8717 TRADD; TNFRSF1A associated via death domain
       7133 TNFRSF1B; TNF receptor superfamily member 1B
       7186 TRAF2; TNF receptor associated factor 2
       2475 MTOR; mechanistic target of rapamycin kinase
       5599 MAPK8; mitogen-activated protein kinase 8
       5602 MAPK10; mitogen-activated protein kinase 10
       5601 MAPK9; mitogen-activated protein kinase 9
       1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
       3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
       8517 IKBKG; inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
       4792 NFKBIA; NFKB inhibitor alpha
       4793 NFKBIB; NFKB inhibitor beta
       4794 NFKBIE; NFKB inhibitor epsilon
       4790 NFKB1; nuclear factor kappa B subunit 1
       5970 RELA; RELA proto-oncogene, NF-kB subunit
       9021 SOCS3; suppressor of cytokine signaling 3
       3667 IRS1; insulin receptor substrate 1
       8660 IRS2; insulin receptor substrate 2
       8471 IRS4; insulin receptor substrate 4
       207 AKT1; AKT serine/threonine kinase 1
       208 AKT2; AKT serine/threonine kinase 2
       10000 AKT3; AKT serine/threonine kinase 3
       948 CD36; CD36 molecule
       23305 ACSL6; acyl-CoA synthetase long chain family member 6
       2182 ACSL4; acyl-CoA synthetase long chain family member 4
       2180 ACSL1; acyl-CoA synthetase long chain family member 1
       51703 ACSL5; acyl-CoA synthetase long chain family member 5
       2181 ACSL3; acyl-CoA synthetase long chain family member 3
       23205 ACSBG1; acyl-CoA synthetase bubblegum family member 1
       81616 ACSBG2; acyl-CoA synthetase bubblegum family member 2
       5588 PRKCQ; protein kinase C theta
       3952 LEP; leptin
       3953 LEPR; leptin receptor
       3717 JAK2; Janus kinase 2
       6774 STAT3; signal transducer and activator of transcription 3
       5443 POMC; proopiomelanocortin
       5562 PRKAA1; protein kinase AMP-activated catalytic subunit alpha 1
       5563 PRKAA2; protein kinase AMP-activated catalytic subunit alpha 2
       5564 PRKAB1; protein kinase AMP-activated non-catalytic subunit beta 1
       5565 PRKAB2; protein kinase AMP-activated non-catalytic subunit beta 2
       5571 PRKAG1; protein kinase AMP-activated non-catalytic subunit gamma 1
       53632 PRKAG3; protein kinase AMP-activated non-catalytic subunit gamma 3
       51422 PRKAG2; protein kinase AMP-activated non-catalytic subunit gamma 2
       181 AGRP; agouti related neuropeptide
       4852 NPY; neuropeptide Y
       10891 PPARGC1A; PPARG coactivator 1 alpha
       5105 PCK1; phosphoenolpyruvate carboxykinase 1
       5106 PCK2; phosphoenolpyruvate carboxykinase 2, mitochondrial
       2538 G6PC1; glucose-6-phosphatase catalytic subunit 1
       57818 G6PC2; glucose-6-phosphatase catalytic subunit 2
       92579 G6PC3; glucose-6-phosphatase catalytic subunit 3
       5781 PTPN11; protein tyrosine phosphatase non-receptor type 11
       5465 PPARA; peroxisome proliferator activated receptor alpha
       6256 RXRA; retinoid X receptor alpha
       6257 RXRB; retinoid X receptor beta
       6258 RXRG; retinoid X receptor gamma
       9370 ADIPOQ; adiponectin, C1Q and collagen domain containing
       51094 ADIPOR1; adiponectin receptor 1
       79602 ADIPOR2; adiponectin receptor 2
       6794 STK11; serine/threonine kinase 11
       10645 CAMKK2; calcium/calmodulin dependent protein kinase kinase 2
       32 ACACB; acetyl-CoA carboxylase beta
       1374 CPT1A; carnitine palmitoyltransferase 1A
       1375 CPT1B; carnitine palmitoyltransferase 1B
       126129 CPT1C; carnitine palmitoyltransferase 1C
       6513 SLC2A1; solute carrier family 2 member 1
       6517 SLC2A4; solute carrier family 2 member 4
K03156 TNF; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A; tumor necrosis factor receptor superfamily member 1A
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K05141 TNFRSF1B; tumor necrosis factor receptor superfamily member 1B
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02581 NFKBIB; NF-kappa-B inhibitor beta
K05872 NFKBIE; NF-kappa-B inhibitor epsilon
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04696 SOCS3; suppressor of cytokine signaling 3
K16172 IRS1; insulin receptor substrate 1
K07187 IRS2; insulin receptor substrate 2
K17446 IRS4; insulin receptor substrate 4
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K06259 CD36; CD36 antigen
K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
K15013 ACSBG; long-chain-fatty-acid--CoA ligase ACSBG [EC:6.2.1.3]
K15013 ACSBG; long-chain-fatty-acid--CoA ligase ACSBG [EC:6.2.1.3]
K18052 PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
K05424 LEP; leptin
K05062 LEPR; leptin receptor
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K04692 STAT3; signal transducer and activator of transcription 3
K05228 POMC; proopiomelanocortin
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K05231 AGRP; agouti related protein
K05232 NPY; neuropeptide Y
K07202 PPARGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K07293 PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]
K07294 NR1C1; peroxisome proliferator-activated receptor alpha
K08524 RXRA; retinoid X receptor alpha
K08525 RXRB; retinoid X receptor beta
K08526 RXRG; retinoid X receptor gamma
K07296 ADIPOQ; adiponectin
K07297 ADIPOR; adiponectin receptor
K07297 ADIPOR; adiponectin receptor
K07298 STK11; serine/threonine-protein kinase 11 [EC:2.7.11.1]
K07359 CAMKK2; calcium/calmodulin-dependent protein kinase kinase 2 [EC:2.7.11.17]
K01946 ACACB; acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K08765 CPT1A; carnitine O-palmitoyltransferase 1, liver isoform [EC:2.3.1.21]
K19523 CPT1B; carnitine O-palmitoyltransferase 1, muscle isoform [EC:2.3.1.21]
K19524 CPT1C; carnitine O-palmitoyltransferase 1, brain isoform [EC:2.3.1.21]
K07299 SLC2A1; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1
K07191 SLC2A4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
     03320 PPAR signaling pathway [PATH:hsa03320]
     04929 GnRH secretion [PATH:hsa04929]
     04912 GnRH signaling pathway [PATH:hsa04912]
     04913 Ovarian steroidogenesis [PATH:hsa04913]
     04915 Estrogen signaling pathway [PATH:hsa04915]
     04914 Progesterone-mediated oocyte maturation [PATH:hsa04914]
     04917 Prolactin signaling pathway [PATH:hsa04917]
     04921 Oxytocin signaling pathway [PATH:hsa04921]
     04926 Relaxin signaling pathway [PATH:hsa04926]
     04935 Growth hormone synthesis, secretion and action [PATH:hsa04935]
     04918 Thyroid hormone synthesis [PATH:hsa04918]
     04919 Thyroid hormone signaling pathway [PATH:hsa04919]
     04928 Parathyroid hormone synthesis, secretion and action [PATH:hsa04928]
     04916 Melanogenesis [PATH:hsa04916]
     04924 Renin secretion [PATH:hsa04924]
     04614 Renin-angiotensin system [PATH:hsa04614]
     04925 Aldosterone synthesis and secretion [PATH:hsa04925]
     04927 Cortisol synthesis and secretion [PATH:hsa04927]
 
   09153 Circulatory system
 
   09154 Digestive system
 
   09155 Excretory system
 
   09156 Nervous system
 
   09157 Sensory system
 
   09158 Development and regeneration
 
   09149 Aging
     04211 Longevity regulating pathway [PATH:hsa04211]
       3630 INS; insulin
       3643 INSR; insulin receptor
       3479 IGF1; insulin like growth factor 1
       3480 IGF1R; insulin like growth factor 1 receptor
       3667 IRS1; insulin receptor substrate 1
       8660 IRS2; insulin receptor substrate 2
       8471 IRS4; insulin receptor substrate 4
       3265 HRAS; HRas proto-oncogene, GTPase
       3845 KRAS; KRAS proto-oncogene, GTPase
       4893 NRAS; NRAS proto-oncogene, GTPase
       5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
       5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
       8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
       207 AKT1; AKT serine/threonine kinase 1
       208 AKT2; AKT serine/threonine kinase 2
       10000 AKT3; AKT serine/threonine kinase 3
       107 ADCY1; adenylate cyclase 1
       108 ADCY2; adenylate cyclase 2
       109 ADCY3; adenylate cyclase 3
       196883 ADCY4; adenylate cyclase 4
       111 ADCY5; adenylate cyclase 5
       112 ADCY6; adenylate cyclase 6
       113 ADCY7; adenylate cyclase 7
       114 ADCY8; adenylate cyclase 8
       115 ADCY9; adenylate cyclase 9
       5566 PRKACA; protein kinase cAMP-activated catalytic subunit alpha
       5567 PRKACB; protein kinase cAMP-activated catalytic subunit beta
       5568 PRKACG; protein kinase cAMP-activated catalytic subunit gamma
       1385 CREB1; cAMP responsive element binding protein 1
       1386 ATF2; activating transcription factor 2
       10488 CREB3; cAMP responsive element binding protein 3
       90993 CREB3L1; cAMP responsive element binding protein 3 like 1
       64764 CREB3L2; cAMP responsive element binding protein 3 like 2
       84699 CREB3L3; cAMP responsive element binding protein 3 like 3
       148327 CREB3L4; cAMP responsive element binding protein 3 like 4
       468 ATF4; activating transcription factor 4
       9586 CREB5; cAMP responsive element binding protein 5
       1388 ATF6B; activating transcription factor 6 beta
       10919 EHMT2; euchromatic histone lysine methyltransferase 2
       79813 EHMT1; euchromatic histone lysine methyltransferase 1
       2308 FOXO1; forkhead box O1
       2309 FOXO3; forkhead box O3
       6648 SOD2; superoxide dismutase 2
       847 CAT; catalase
       9474 ATG5; autophagy related 5
       9365 KL; klotho
       7248 TSC1; TSC complex subunit 1
       7249 TSC2; TSC complex subunit 2
       6009 RHEB; Ras homolog, mTORC1 binding
       2475 MTOR; mechanistic target of rapamycin kinase
       57521 RPTOR; regulatory associated protein of MTOR complex 1
       84335 AKT1S1; AKT1 substrate 1
       8408 ULK1; unc-51 like autophagy activating kinase 1
       9776 ATG13; autophagy related 13
       9821 RB1CC1; RB1 inducible coiled-coil 1
       60673 ATG101; autophagy related 101
       6198 RPS6KB1; ribosomal protein S6 kinase B1
       6199 RPS6KB2; ribosomal protein S6 kinase B2
       1978 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
       1977 EIF4E; eukaryotic translation initiation factor 4E
       9470 EIF4E2; eukaryotic translation initiation factor 4E family member 2
       253314 EIF4E1B; eukaryotic translation initiation factor 4E family member 1B
       9370 ADIPOQ; adiponectin, C1Q and collagen domain containing
       51094 ADIPOR1; adiponectin receptor 1
       79602 ADIPOR2; adiponectin receptor 2
       26060 APPL1; adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
       10645 CAMKK2; calcium/calmodulin dependent protein kinase kinase 2
       5562 PRKAA1; protein kinase AMP-activated catalytic subunit alpha 1
       5563 PRKAA2; protein kinase AMP-activated catalytic subunit alpha 2
       5564 PRKAB1; protein kinase AMP-activated non-catalytic subunit beta 1
       5565 PRKAB2; protein kinase AMP-activated non-catalytic subunit beta 2
       5571 PRKAG1; protein kinase AMP-activated non-catalytic subunit gamma 1
       53632 PRKAG3; protein kinase AMP-activated non-catalytic subunit gamma 3
       51422 PRKAG2; protein kinase AMP-activated non-catalytic subunit gamma 2
       23411 SIRT1; sirtuin 1
       581 BAX; BCL2 associated X, apoptosis regulator
       7157 TP53; tumor protein p53
       4790 NFKB1; nuclear factor kappa B subunit 1
       5970 RELA; RELA proto-oncogene, NF-kB subunit
       5468 PPARG; peroxisome proliferator activated receptor gamma
       10891 PPARGC1A; PPARG coactivator 1 alpha
       6794 STK11; serine/threonine kinase 11
       27244 SESN1; sestrin 1
       143686 SESN3; sestrin 3
       83667 SESN2; sestrin 2
       814 CAMK4; calcium/calmodulin dependent protein kinase IV
K04526 INS; insulin
K04527 INSR; insulin receptor [EC:2.7.10.1]
K05459 IGF1; insulin-like growth factor 1
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K16172 IRS1; insulin receptor substrate 1
K07187 IRS2; insulin receptor substrate 2
K17446 IRS4; insulin receptor substrate 4
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04450 ATF2; cyclic AMP-dependent transcription factor ATF-2
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K04374 ATF4; cyclic AMP-dependent transcription factor ATF-4
K09047 CREB5; cyclic AMP-responsive element-binding protein 5
K09049 ATF6B; cyclic AMP-dependent transcription factor ATF-6 beta
K11420 EHMT; [histone H3]-lysine9 N-trimethyltransferase EHMT [EC:2.1.1.355]
K11420 EHMT; [histone H3]-lysine9 N-trimethyltransferase EHMT [EC:2.1.1.355]
K07201 FOXO1; forkhead box protein O1
K09408 FOXO3; forkhead box protein O3
K04564 SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
K03781 katE; catalase [EC:1.11.1.6]
K08339 ATG5; autophagy-related protein 5
K14756 KL; klotho [EC:3.2.1.31]
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K07208 RHEB; Ras homolog enriched in brain
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07204 RAPTOR; regulatory associated protein of mTOR
K16184 AKT1S1; proline-rich AKT1 substrate 1
K21357 ULK1; serine/threonine-protein kinase ULK1 [EC:2.7.11.1]
K08331 ATG13; autophagy-related protein 13
K17589 RB1CC1; RB1-inducible coiled-coil protein 1
K19730 ATG101; autophagy-related protein 101
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K03259 EIF4E; translation initiation factor 4E
K03259 EIF4E; translation initiation factor 4E
K03259 EIF4E; translation initiation factor 4E
K07296 ADIPOQ; adiponectin
K07297 ADIPOR; adiponectin receptor
K07297 ADIPOR; adiponectin receptor
K08733 APPL1; DCC-interacting protein 13 alpha
K07359 CAMKK2; calcium/calmodulin-dependent protein kinase kinase 2 [EC:2.7.11.17]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K11411 SIRT1; NAD+-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]
K02159 BAX; apoptosis regulator BAX
K04451 TP53; tumor protein p53
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K08530 NR1C3; peroxisome proliferator-activated receptor gamma
K07202 PPARGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
K07298 STK11; serine/threonine-protein kinase 11 [EC:2.7.11.1]
K10141 SESN1_3; sestrin 1/3
K10141 SESN1_3; sestrin 1/3
K20394 SESN2; sestrin 2
K05869 CAMK4; calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17]
     04212 Longevity regulating pathway - worm
     04213 Longevity regulating pathway - multiple species [PATH:hsa04213]
 
   09159 Environmental adaptation
 
 09160 Human Diseases
 
   09161 Cancer: overview
 
   09162 Cancer: specific types
 
   09163 Immune disease
 
   09164 Neurodegenerative disease
 
   09165 Substance dependence
 
   09166 Cardiovascular disease
 
   09167 Endocrine and metabolic disease
     04930 Type II diabetes mellitus [PATH:hsa04930]
     04940 Type I diabetes mellitus [PATH:hsa04940]
     04950 Maturity onset diabetes of the young [PATH:hsa04950]
     04932 Non-alcoholic fatty liver disease [PATH:hsa04932]
       3569 IL6; interleukin 6
       3570 IL6R; interleukin 6 receptor
       9021 SOCS3; suppressor of cytokine signaling 3
       7124 TNF; tumor necrosis factor
       7132 TNFRSF1A; TNF receptor superfamily member 1A
       4790 NFKB1; nuclear factor kappa B subunit 1
       5970 RELA; RELA proto-oncogene, NF-kB subunit
       3630 INS; insulin
       3643 INSR; insulin receptor
       3667 IRS1; insulin receptor substrate 1
       8660 IRS2; insulin receptor substrate 2
       5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
       5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
       8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
       207 AKT1; AKT serine/threonine kinase 1
       208 AKT2; AKT serine/threonine kinase 2
       10000 AKT3; AKT serine/threonine kinase 3
       2931 GSK3A; glycogen synthase kinase 3 alpha
       2932 GSK3B; glycogen synthase kinase 3 beta
       10062 NR1H3; nuclear receptor subfamily 1 group H member 3
       6256 RXRA; retinoid X receptor alpha
       6720 SREBF1; sterol regulatory element binding transcription factor 1
       6945 MLX; MAX dimerization protein MLX
       22877 MLXIP; MLX interacting protein
       51085 MLXIPL; MLX interacting protein like
       5313 PKLR; pyruvate kinase L/R
       3952 LEP; leptin
       3953 LEPR; leptin receptor
       9370 ADIPOQ; adiponectin, C1Q and collagen domain containing
       51094 ADIPOR1; adiponectin receptor 1
       79602 ADIPOR2; adiponectin receptor 2
       5562 PRKAA1; protein kinase AMP-activated catalytic subunit alpha 1
       5563 PRKAA2; protein kinase AMP-activated catalytic subunit alpha 2
       5564 PRKAB1; protein kinase AMP-activated non-catalytic subunit beta 1
       5565 PRKAB2; protein kinase AMP-activated non-catalytic subunit beta 2
       5571 PRKAG1; protein kinase AMP-activated non-catalytic subunit gamma 1
       53632 PRKAG3; protein kinase AMP-activated non-catalytic subunit gamma 3
       51422 PRKAG2; protein kinase AMP-activated non-catalytic subunit gamma 2
       5465 PPARA; peroxisome proliferator activated receptor alpha
       998 CDC42; cell division cycle 42
       5879 RAC1; Rac family small GTPase 1
       4296 MAP3K11; mitogen-activated protein kinase kinase kinase 11
       5599 MAPK8; mitogen-activated protein kinase 8
       5602 MAPK10; mitogen-activated protein kinase 10
       5601 MAPK9; mitogen-activated protein kinase 9
       83737 ITCH; itchy E3 ubiquitin protein ligase
       2081 ERN1; endoplasmic reticulum to nucleus signaling 1
       7186 TRAF2; TNF receptor associated factor 2
       4217 MAP3K5; mitogen-activated protein kinase kinase kinase 5
       2353 FOS; Fos proto-oncogene, AP-1 transcription factor subunit
       3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
       3552 IL1A; interleukin 1 alpha
       3553 IL1B; interleukin 1 beta
       3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
       7494 XBP1; X-box binding protein 1
       1050 CEBPA; CCAAT enhancer binding protein alpha
       1571 CYP2E1; cytochrome P450 family 2 subfamily E member 1
       356 FASLG; Fas ligand
       3576 CXCL8; C-X-C motif chemokine ligand 8
       7040 TGFB1; transforming growth factor beta 1
       9451 EIF2AK3; eukaryotic translation initiation factor 2 alpha kinase 3
       1965 EIF2S1; eukaryotic translation initiation factor 2 subunit alpha
       468 ATF4; activating transcription factor 4
       1649 DDIT3; DNA damage inducible transcript 3
       10018 BCL2L11; BCL2 like 11
       581 BAX; BCL2 associated X, apoptosis regulator
       355 FAS; Fas cell surface death receptor
       841 CASP8; caspase 8
       637 BID; BH3 interacting domain death agonist
       54205 CYCS; cytochrome c, somatic
       836 CASP3; caspase 3
       840 CASP7; caspase 7
       4723 NDUFV1; NADH:ubiquinone oxidoreductase core subunit V1
       4729 NDUFV2; NADH:ubiquinone oxidoreductase core subunit V2
       4731 NDUFV3; NADH:ubiquinone oxidoreductase subunit V3
       4694 NDUFA1; NADH:ubiquinone oxidoreductase subunit A1
       4695 NDUFA2; NADH:ubiquinone oxidoreductase subunit A2
       4696 NDUFA3; NADH:ubiquinone oxidoreductase subunit A3
       4697 NDUFA4; NDUFA4 mitochondrial complex associated
       56901 NDUFA4L2; NDUFA4 mitochondrial complex associated like 2
       4698 NDUFA5; NADH:ubiquinone oxidoreductase subunit A5
       4700 NDUFA6; NADH:ubiquinone oxidoreductase subunit A6
       4701 NDUFA7; NADH:ubiquinone oxidoreductase subunit A7
       4702 NDUFA8; NADH:ubiquinone oxidoreductase subunit A8
       4704 NDUFA9; NADH:ubiquinone oxidoreductase subunit A9
       4705 NDUFA10; NADH:ubiquinone oxidoreductase subunit A10
       4706 NDUFAB1; NADH:ubiquinone oxidoreductase subunit AB1
       126328 NDUFA11; NADH:ubiquinone oxidoreductase subunit A11
       55967 NDUFA12; NADH:ubiquinone oxidoreductase subunit A12
       51079 NDUFA13; NADH:ubiquinone oxidoreductase subunit A13
       4707 NDUFB1; NADH:ubiquinone oxidoreductase subunit B1
       4708 NDUFB2; NADH:ubiquinone oxidoreductase subunit B2
       4709 NDUFB3; NADH:ubiquinone oxidoreductase subunit B3
       4710 NDUFB4; NADH:ubiquinone oxidoreductase subunit B4
       4711 NDUFB5; NADH:ubiquinone oxidoreductase subunit B5
       4712 NDUFB6; NADH:ubiquinone oxidoreductase subunit B6
       4713 NDUFB7; NADH:ubiquinone oxidoreductase subunit B7
       4714 NDUFB8; NADH:ubiquinone oxidoreductase subunit B8
       4715 NDUFB9; NADH:ubiquinone oxidoreductase subunit B9
       4716 NDUFB10; NADH:ubiquinone oxidoreductase subunit B10
       54539 NDUFB11; NADH:ubiquinone oxidoreductase subunit B11
       4719 NDUFS1; NADH:ubiquinone oxidoreductase core subunit S1
       4720 NDUFS2; NADH:ubiquinone oxidoreductase core subunit S2
       4722 NDUFS3; NADH:ubiquinone oxidoreductase core subunit S3
       4724 NDUFS4; NADH:ubiquinone oxidoreductase subunit S4
       4725 NDUFS5; NADH:ubiquinone oxidoreductase subunit S5
       4726 NDUFS6; NADH:ubiquinone oxidoreductase subunit S6
       374291 NDUFS7; NADH:ubiquinone oxidoreductase core subunit S7
       4728 NDUFS8; NADH:ubiquinone oxidoreductase core subunit S8
       4717 NDUFC1; NADH:ubiquinone oxidoreductase subunit C1
       4718 NDUFC2; NADH:ubiquinone oxidoreductase subunit C2
       100532726 NDUFC2-KCTD14; NDUFC2-KCTD14 readthrough
       6389 SDHA; succinate dehydrogenase complex flavoprotein subunit A
       6390 SDHB; succinate dehydrogenase complex iron sulfur subunit B
       6391 SDHC; succinate dehydrogenase complex subunit C
       6392 SDHD; succinate dehydrogenase complex subunit D
       7386 UQCRFS1; ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
       4519 CYTB; cytochrome b
       1537 CYC1; cytochrome c1
       7384 UQCRC1; ubiquinol-cytochrome c reductase core protein 1
       7385 UQCRC2; ubiquinol-cytochrome c reductase core protein 2
       7388 UQCRH; ubiquinol-cytochrome c reductase hinge protein
       440567 UQCRHL; ubiquinol-cytochrome c reductase hinge protein like
       7381 UQCRB; ubiquinol-cytochrome c reductase binding protein
       27089 UQCRQ; ubiquinol-cytochrome c reductase complex III subunit VII
       29796 UQCR10; ubiquinol-cytochrome c reductase, complex III subunit X
       10975 UQCR11; ubiquinol-cytochrome c reductase, complex III subunit XI
       4514 COX3; cytochrome c oxidase subunit III
       4512 COX1; cytochrome c oxidase subunit I
       4513 COX2; cytochrome c oxidase subunit II
       84701 COX4I2; cytochrome c oxidase subunit 4I2
       1327 COX4I1; cytochrome c oxidase subunit 4I1
       9377 COX5A; cytochrome c oxidase subunit 5A
       1329 COX5B; cytochrome c oxidase subunit 5B
       1337 COX6A1; cytochrome c oxidase subunit 6A1
       1339 COX6A2; cytochrome c oxidase subunit 6A2
       1340 COX6B1; cytochrome c oxidase subunit 6B1
       125965 COX6B2; cytochrome c oxidase subunit 6B2
       1345 COX6C; cytochrome c oxidase subunit 6C
       1346 COX7A1; cytochrome c oxidase subunit 7A1
       1347 COX7A2; cytochrome c oxidase subunit 7A2
       9167 COX7A2L; cytochrome c oxidase subunit 7A2 like
       1349 COX7B; cytochrome c oxidase subunit 7B
       170712 COX7B2; cytochrome c oxidase subunit 7B2
       1350 COX7C; cytochrome c oxidase subunit 7C
       341947 COX8C; cytochrome c oxidase subunit 8C
       1351 COX8A; cytochrome c oxidase subunit 8A
K05405 IL6; interleukin 6
K05055 IL6R; interleukin 6 receptor
K04696 SOCS3; suppressor of cytokine signaling 3
K03156 TNF; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A; tumor necrosis factor receptor superfamily member 1A
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04526 INS; insulin
K04527 INSR; insulin receptor [EC:2.7.10.1]
K16172 IRS1; insulin receptor substrate 1
K07187 IRS2; insulin receptor substrate 2
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K08822 GSK3A; glycogen synthase kinase 3 alpha [EC:2.7.11.26]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K08536 NR1H3; liver X receptor alpha
K08524 RXRA; retinoid X receptor alpha
K07197 SREBP1; sterol regulatory element-binding transcription factor 1
K09113 MLX; MAX-like protein X
K09113 MLX; MAX-like protein X
K09113 MLX; MAX-like protein X
K12406 PKLR; pyruvate kinase isozymes R/L [EC:2.7.1.40]
K05424 LEP; leptin
K05062 LEPR; leptin receptor
K07296 ADIPOQ; adiponectin
K07297 ADIPOR; adiponectin receptor
K07297 ADIPOR; adiponectin receptor
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K07294 NR1C1; peroxisome proliferator-activated receptor alpha
K04393 CDC42; cell division control protein 42
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K04419 MAP3K11; mitogen-activated protein kinase kinase kinase 11 [EC:2.7.11.25]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K05632 ITCH; E3 ubiquitin-protein ligase Itchy [EC:2.3.2.26]
K08852 ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K04426 MAP3K5; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K09027 XBP1; X box-binding protein 1
K09055 CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
K07415 CYP2E1; cytochrome P450 family 2 subfamily E1 [EC:1.14.14.-]
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K10030 IL8; interleukin 8
K13375 TGFB1; transforming growth factor beta-1
K08860 EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
K03237 EIF2S1; translation initiation factor 2 subunit 1
K04374 ATF4; cyclic AMP-dependent transcription factor ATF-4
K04452 DDIT3; DNA damage-inducible transcript 3
K16341 BCL2L11; Bcl-2-like protein 11
K02159 BAX; apoptosis regulator BAX
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04726 BID; BH3 interacting domain death agonist
K08738 CYC; cytochrome c
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K03942 NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2]
K03943 NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:7.1.1.2]
K03944 NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
K03945 NDUFA1; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 1
K03946 NDUFA2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2
K03947 NDUFA3; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 3
K03948 NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4
K03948 NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4
K03949 NDUFA5; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 5
K03950 NDUFA6; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6
K03951 NDUFA7; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7
K03952 NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 8
K03953 NDUFA9; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 9
K03954 NDUFA10; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10
K03955 NDUFAB1; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1, acyl-carrier protein
K03956 NDUFA11; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 11
K11352 NDUFA12; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 12
K11353 NDUFA13; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13
K03957 NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
K03958 NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
K03959 NDUFB3; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3
K03960 NDUFB4; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 4
K03961 NDUFB5; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5
K03962 NDUFB6; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6
K03963 NDUFB7; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7
K03964 NDUFB8; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8
K03965 NDUFB9; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9
K03966 NDUFB10; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10
K11351 NDUFB11; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11
K03934 NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:7.1.1.2]
K03935 NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:7.1.1.2]
K03936 NDUFS3; NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:7.1.1.2]
K03937 NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4
K03938 NDUFS5; NADH dehydrogenase (ubiquinone) Fe-S protein 5
K03939 NDUFS6; NADH dehydrogenase (ubiquinone) Fe-S protein 6
K03940 NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:7.1.1.2]
K03941 NDUFS8; NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:7.1.1.2]
K03967 NDUFC1; NADH dehydrogenase (ubiquinone) 1 subunit C1
K03968 NDUFC2; NADH dehydrogenase (ubiquinone) 1 subunit C2
K03968 NDUFC2; NADH dehydrogenase (ubiquinone) 1 subunit C2
K00234 SDHA; succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]
K00235 SDHB; succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1]
K00236 SDHC; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
K00237 SDHD; succinate dehydrogenase (ubiquinone) membrane anchor subunit
K00411 UQCRFS1; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit
K00413 CYC1; ubiquinol-cytochrome c reductase cytochrome c1 subunit
K00414 QCR1; ubiquinol-cytochrome c reductase core subunit 1
K00415 QCR2; ubiquinol-cytochrome c reductase core subunit 2
K00416 QCR6; ubiquinol-cytochrome c reductase subunit 6
K00416 QCR6; ubiquinol-cytochrome c reductase subunit 6
K00417 QCR7; ubiquinol-cytochrome c reductase subunit 7
K00418 QCR8; ubiquinol-cytochrome c reductase subunit 8
K00419 QCR9; ubiquinol-cytochrome c reductase subunit 9
K00420 QCR10; ubiquinol-cytochrome c reductase subunit 10
K02262 COX3; cytochrome c oxidase subunit 3
K02256 COX1; cytochrome c oxidase subunit 1 [EC:7.1.1.9]
K02261 COX2; cytochrome c oxidase subunit 2
K02263 COX4; cytochrome c oxidase subunit 4
K02263 COX4; cytochrome c oxidase subunit 4
K02264 COX5A; cytochrome c oxidase subunit 5a
K02265 COX5B; cytochrome c oxidase subunit 5b
K02266 COX6A; cytochrome c oxidase subunit 6a
K02266 COX6A; cytochrome c oxidase subunit 6a
K02267 COX6B; cytochrome c oxidase subunit 6b
K02267 COX6B; cytochrome c oxidase subunit 6b
K02268 COX6C; cytochrome c oxidase subunit 6c
K02270 COX7A; cytochrome c oxidase subunit 7a
K02270 COX7A; cytochrome c oxidase subunit 7a
K02270 COX7A; cytochrome c oxidase subunit 7a
K02271 COX7B; cytochrome c oxidase subunit 7b
K02271 COX7B; cytochrome c oxidase subunit 7b
K02272 COX7C; cytochrome c oxidase subunit 7c
K02273 COX8; cytochrome c oxidase subunit 8
K02273 COX8; cytochrome c oxidase subunit 8
     04931 Insulin resistance [PATH:hsa04931]
     04933 AGE-RAGE signaling pathway in diabetic complications [PATH:hsa04933]
     04934 Cushing syndrome [PATH:hsa04934]
 
   09171 Infectious disease: bacterial
 
   09172 Infectious disease: viral
 
   09174 Infectious disease: parasitic
 
   09175 Drug resistance: antimicrobial
 
   09176 Drug resistance: antineoplastic
 
 09180 Brite Hierarchies
 
 09190 Not Included in Pathway or Brite

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: January 25, 2021