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KO |
 09100 Metabolism
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09101 Carbohydrate metabolism
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00010 Glycolysis / Gluconeogenesis [PATH:hsa00010]
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 10327 AKR1A1; aldo-keto reductase family 1 member A1
124 ADH1A; alcohol dehydrogenase 1A (class I), alpha polypeptide
125 ADH1B; alcohol dehydrogenase 1B (class I), beta polypeptide
126 ADH1C; alcohol dehydrogenase 1C (class I), gamma polypeptide
127 ADH4; alcohol dehydrogenase 4 (class II), pi polypeptide
128 ADH5; alcohol dehydrogenase 5 (class III), chi polypeptide
130 ADH6; alcohol dehydrogenase 6 (class V)
130589 GALM; galactose mutarotase
131 ADH7; alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
160287 LDHAL6A; lactate dehydrogenase A like 6A
1737 DLAT; dihydrolipoamide S-acetyltransferase
1738 DLD; dihydrolipoamide dehydrogenase
2023 ENO1; enolase 1
2026 ENO2; enolase 2
2027 ENO3; enolase 3
217 ALDH2; aldehyde dehydrogenase 2 family member
218 ALDH3A1; aldehyde dehydrogenase 3 family member A1
219 ALDH1B1; aldehyde dehydrogenase 1 family member B1
2203 FBP1; fructose-bisphosphatase 1
221 ALDH3B1; aldehyde dehydrogenase 3 family member B1
222 ALDH3B2; aldehyde dehydrogenase 3 family member B2
223 ALDH9A1; aldehyde dehydrogenase 9 family member A1
224 ALDH3A2; aldehyde dehydrogenase 3 family member A2
226 ALDOA; aldolase, fructose-bisphosphate A
229 ALDOB; aldolase, fructose-bisphosphate B
230 ALDOC; aldolase, fructose-bisphosphate C
2538 G6PC1; glucose-6-phosphatase catalytic subunit 1
2597 GAPDH; glyceraldehyde-3-phosphate dehydrogenase
26330 GAPDHS; glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
2645 GCK; glucokinase
2821 GPI; glucose-6-phosphate isomerase
3098 HK1; hexokinase 1
3099 HK2; hexokinase 2
3101 HK3; hexokinase 3
387712 ENO4; enolase 4
3939 LDHA; lactate dehydrogenase A
3945 LDHB; lactate dehydrogenase B
3948 LDHC; lactate dehydrogenase C
441531 PGAM4; phosphoglycerate mutase family member 4
501 ALDH7A1; aldehyde dehydrogenase 7 family member A1
5105 PCK1; phosphoenolpyruvate carboxykinase 1
5106 PCK2; phosphoenolpyruvate carboxykinase 2, mitochondrial
5160 PDHA1; pyruvate dehydrogenase E1 subunit alpha 1
5161 PDHA2; pyruvate dehydrogenase E1 subunit alpha 2
5162 PDHB; pyruvate dehydrogenase E1 subunit beta
5211 PFKL; phosphofructokinase, liver type
5213 PFKM; phosphofructokinase, muscle
5214 PFKP; phosphofructokinase, platelet
5223 PGAM1; phosphoglycerate mutase 1
5224 PGAM2; phosphoglycerate mutase 2
5230 PGK1; phosphoglycerate kinase 1
5232 PGK2; phosphoglycerate kinase 2
5236 PGM1; phosphoglucomutase 1
5313 PKLR; pyruvate kinase L/R
5315 PKM; pyruvate kinase M1/2
55276 PGM2; phosphoglucomutase 2
55902 ACSS2; acyl-CoA synthetase short chain family member 2
57818 G6PC2; glucose-6-phosphatase catalytic subunit 2
669 BPGM; bisphosphoglycerate mutase
7167 TPI1; triosephosphate isomerase 1
80201 HKDC1; hexokinase domain containing 1
83440 ADPGK; ADP dependent glucokinase
84532 ACSS1; acyl-CoA synthetase short chain family member 1
8789 FBP2; fructose-bisphosphatase 2
92483 LDHAL6B; lactate dehydrogenase A like 6B
92579 G6PC3; glucose-6-phosphatase catalytic subunit 3
9562 MINPP1; multiple inositol-polyphosphate phosphatase 1
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K00002 AKR1A1; alcohol dehydrogenase (NADP+) [EC:1.1.1.2]
K13951 ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]
K13951 ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]
K13951 ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]
K13980 ADH4; alcohol dehydrogenase 4 [EC:1.1.1.1]
K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]
K13952 ADH6; alcohol dehydrogenase 6 [EC:1.1.1.1]
K01785 galM; aldose 1-epimerase [EC:5.1.3.3]
K13951 ADH1_7; alcohol dehydrogenase 1/7 [EC:1.1.1.1]
K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase) [EC:2.3.1.12]
K00382 DLD; dihydrolipoamide dehydrogenase [EC:1.8.1.4]
K01689 ENO; enolase [EC:4.2.1.11]
K01689 ENO; enolase [EC:4.2.1.11]
K01689 ENO; enolase [EC:4.2.1.11]
K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
K00129 ALDH3; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
K00129 ALDH3; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K00129 ALDH3; aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K00149 ALDH9A1; aldehyde dehydrogenase family 9 member A1 [EC:1.2.1.47 1.2.1.3]
K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12]
K10705 GAPDHS; glyceraldehyde-3-phosphate dehydrogenase, spermatogenic [EC:1.2.1.12]
K12407 GCK; glucokinase [EC:2.7.1.2]
K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
K00844 HK; hexokinase [EC:2.7.1.1]
K00844 HK; hexokinase [EC:2.7.1.1]
K00844 HK; hexokinase [EC:2.7.1.1]
K01689 ENO; enolase [EC:4.2.1.11]
K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
K14085 ALDH7A1; aldehyde dehydrogenase family 7 member A1 [EC:1.2.1.31 1.2.1.8 1.2.1.3]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K00161 PDHA; pyruvate dehydrogenase E1 component alpha subunit [EC:1.2.4.1]
K00161 PDHA; pyruvate dehydrogenase E1 component alpha subunit [EC:1.2.4.1]
K00162 PDHB; pyruvate dehydrogenase E1 component beta subunit [EC:1.2.4.1]
K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
K12406 PKLR; pyruvate kinase isozymes R/L [EC:2.7.1.40]
K00873 PK; pyruvate kinase [EC:2.7.1.40]
K15779 PGM2; phosphoglucomutase / phosphopentomutase [EC:5.4.2.2 5.4.2.7]
K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K01837 BPGM; bisphosphoglycerate/phosphoglycerate mutase [EC:5.4.2.4 5.4.2.11]
K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
K00844 HK; hexokinase [EC:2.7.1.1]
K08074 ADPGK; ADP-dependent glucokinase [EC:2.7.1.147]
K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K03103 MINPP1; multiple inositol-polyphosphate phosphatase / 2,3-bisphosphoglycerate 3-phosphatase [EC:3.1.3.62 3.1.3.80]
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 00020 Citrate cycle (TCA cycle) [PATH:hsa00020]
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00030 Pentose phosphate pathway [PATH:hsa00030]
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00040 Pentose and glucuronate interconversions [PATH:hsa00040]
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00051 Fructose and mannose metabolism [PATH:hsa00051]
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00052 Galactose metabolism [PATH:hsa00052]
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00053 Ascorbate and aldarate metabolism [PATH:hsa00053]
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00500 Starch and sucrose metabolism [PATH:hsa00500]
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00520 Amino sugar and nucleotide sugar metabolism [PATH:hsa00520]
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00620 Pyruvate metabolism [PATH:hsa00620]
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10873 ME3; malic enzyme 3
134526 ACOT12; acyl-CoA thioesterase 12
160287 LDHAL6A; lactate dehydrogenase A like 6A
1737 DLAT; dihydrolipoamide S-acetyltransferase
1738 DLD; dihydrolipoamide dehydrogenase
197257 LDHD; lactate dehydrogenase D
217 ALDH2; aldehyde dehydrogenase 2 family member
219 ALDH1B1; aldehyde dehydrogenase 1 family member B1
223 ALDH9A1; aldehyde dehydrogenase 9 family member A1
224 ALDH3A2; aldehyde dehydrogenase 3 family member A2
2271 FH; fumarate hydratase
2739 GLO1; glyoxalase I
3029 HAGH; hydroxyacylglutathione hydrolase
31 ACACA; acetyl-CoA carboxylase alpha
32 ACACB; acetyl-CoA carboxylase beta
38 ACAT1; acetyl-CoA acetyltransferase 1
39 ACAT2; acetyl-CoA acetyltransferase 2
3939 LDHA; lactate dehydrogenase A
3945 LDHB; lactate dehydrogenase B
3948 LDHC; lactate dehydrogenase C
4190 MDH1; malate dehydrogenase 1
4191 MDH2; malate dehydrogenase 2
4199 ME1; malic enzyme 1
4200 ME2; malic enzyme 2
501 ALDH7A1; aldehyde dehydrogenase 7 family member A1
5091 PC; pyruvate carboxylase
5105 PCK1; phosphoenolpyruvate carboxykinase 1
5106 PCK2; phosphoenolpyruvate carboxykinase 2, mitochondrial
5160 PDHA1; pyruvate dehydrogenase E1 subunit alpha 1
5161 PDHA2; pyruvate dehydrogenase E1 subunit alpha 2
5162 PDHB; pyruvate dehydrogenase E1 subunit beta
5313 PKLR; pyruvate kinase L/R
5315 PKM; pyruvate kinase M1/2
55902 ACSS2; acyl-CoA synthetase short chain family member 2
84532 ACSS1; acyl-CoA synthetase short chain family member 1
92483 LDHAL6B; lactate dehydrogenase A like 6B
9380 GRHPR; glyoxylate and hydroxypyruvate reductase
97 ACYP1; acylphosphatase 1
98 ACYP2; acylphosphatase 2
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K00029 E1.1.1.40; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40]
K01067 E3.1.2.1; acetyl-CoA hydrolase [EC:3.1.2.1]
K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase) [EC:2.3.1.12]
K00382 DLD; dihydrolipoamide dehydrogenase [EC:1.8.1.4]
K00102 LDHD; D-lactate dehydrogenase (cytochrome) [EC:1.1.2.4]
K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
K00149 ALDH9A1; aldehyde dehydrogenase family 9 member A1 [EC:1.2.1.47 1.2.1.3]
K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
K01759 GLO1; lactoylglutathione lyase [EC:4.4.1.5]
K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6]
K11262 ACACA; acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K01946 ACACB; acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
K00025 MDH1; malate dehydrogenase [EC:1.1.1.37]
K00026 MDH2; malate dehydrogenase [EC:1.1.1.37]
K00029 E1.1.1.40; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40]
K00027 ME2; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38]
K14085 ALDH7A1; aldehyde dehydrogenase family 7 member A1 [EC:1.2.1.31 1.2.1.8 1.2.1.3]
K01958 PC; pyruvate carboxylase [EC:6.4.1.1]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K00161 PDHA; pyruvate dehydrogenase E1 component alpha subunit [EC:1.2.4.1]
K00161 PDHA; pyruvate dehydrogenase E1 component alpha subunit [EC:1.2.4.1]
K00162 PDHB; pyruvate dehydrogenase E1 component beta subunit [EC:1.2.4.1]
K12406 PKLR; pyruvate kinase isozymes R/L [EC:2.7.1.40]
K00873 PK; pyruvate kinase [EC:2.7.1.40]
K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
K00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]
K00049 GRHPR; glyoxylate/hydroxypyruvate reductase [EC:1.1.1.79 1.1.1.81]
K01512 acyP; acylphosphatase [EC:3.6.1.7]
K01512 acyP; acylphosphatase [EC:3.6.1.7]
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00630 Glyoxylate and dicarboxylate metabolism [PATH:hsa00630]
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00640 Propanoate metabolism [PATH:hsa00640]
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00650 Butanoate metabolism [PATH:hsa00650]
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00660 C5-Branched dibasic acid metabolism
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00562 Inositol phosphate metabolism [PATH:hsa00562]
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09102 Energy metabolism
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09103 Lipid metabolism
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09104 Nucleotide metabolism
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00230 Purine metabolism [PATH:hsa00230]
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100 ADA; adenosine deaminase
100526794 NT5C1B-RDH14; NT5C1B-RDH14 readthrough
10201 NME6; NME/NM23 nucleoside diphosphate kinase 6
102157402 AK6; adenylate kinase 6
10606 PAICS; phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
107 ADCY1; adenylate cyclase 1
108 ADCY2; adenylate cyclase 2
10846 PDE10A; phosphodiesterase 10A
109 ADCY3; adenylate cyclase 3
111 ADCY5; adenylate cyclase 5
11164 NUDT5; nudix hydrolase 5
112 ADCY6; adenylate cyclase 6
113 ADCY7; adenylate cyclase 7
114 ADCY8; adenylate cyclase 8
115 ADCY9; adenylate cyclase 9
115024 NT5C3B; 5'-nucleotidase, cytosolic IIIB
122481 AK7; adenylate kinase 7
122622 ADSS1; adenylosuccinate synthase 1
124583 CANT1; calcium activated nucleotidase 1
131870 NUDT16; nudix hydrolase 16
132 ADK; adenosine kinase
158 ADSL; adenylosuccinate lyase
158067 AK8; adenylate kinase 8
159 ADSS2; adenylosuccinate synthase 2
1633 DCK; deoxycytidine kinase
1716 DGUOK; deoxyguanosine kinase
196883 ADCY4; adenylate cyclase 4
203 AK1; adenylate kinase 1
204 AK2; adenylate kinase 2
205 AK4; adenylate kinase 4
221264 AK9; adenylate kinase 9
221823 PRPS1L1; phosphoribosyl pyrophosphate synthetase 1 like 1
2272 FHIT; fragile histidine triad diadenosine triphosphatase
22875 ENPP4; ectonucleotide pyrophosphatase/phosphodiesterase 4
22978 NT5C2; 5'-nucleotidase, cytosolic II
2618 GART; phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
26289 AK5; adenylate kinase 5
270 AMPD1; adenosine monophosphate deaminase 1
271 AMPD2; adenosine monophosphate deaminase 2
27115 PDE7B; phosphodiesterase 7B
272 AMPD3; adenosine monophosphate deaminase 3
2766 GMPR; guanosine monophosphate reductase
2977 GUCY1A2; guanylate cyclase 1 soluble subunit alpha 2
2982 GUCY1A1; guanylate cyclase 1 soluble subunit alpha 1
2983 GUCY1B1; guanylate cyclase 1 soluble subunit beta 1
2984 GUCY2C; guanylate cyclase 2C
2986 GUCY2F; guanylate cyclase 2F, retinal
2987 GUK1; guanylate kinase 1
29922 NME7; NME/NM23 family member 7
3000 GUCY2D; guanylate cyclase 2D, retinal
30833 NT5C; 5', 3'-nucleotidase, cytosolic
318 NUDT2; nudix hydrolase 2
3251 HPRT1; hypoxanthine phosphoribosyltransferase 1
353 APRT; adenine phosphoribosyltransferase
3614 IMPDH1; inosine monophosphate dehydrogenase 1
3615 IMPDH2; inosine monophosphate dehydrogenase 2
3704 ITPA; inosine triphosphatase
374659 HDDC3; HD domain containing 3
377841 ENTPD8; ectonucleoside triphosphate diphosphohydrolase 8
390877 adenylate kinase isoenzyme 1-like
471 ATIC; 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
4830 NME1; NME/NM23 nucleoside diphosphate kinase 1
4831 NME2; NME/NM23 nucleoside diphosphate kinase 2
4832 NME3; NME/NM23 nucleoside diphosphate kinase 3
4833 NME4; NME/NM23 nucleoside diphosphate kinase 4
4860 PNP; purine nucleoside phosphorylase
4881 NPR1; natriuretic peptide receptor 1
4882 NPR2; natriuretic peptide receptor 2
4907 NT5E; 5'-nucleotidase ecto
50484 RRM2B; ribonucleotide reductase regulatory TP53 inducible subunit M2B
50808 AK3; adenylate kinase 3
50940 PDE11A; phosphodiesterase 11A
51251 NT5C3A; 5'-nucleotidase, cytosolic IIIA
51292 GMPR2; guanosine monophosphate reductase 2
5136 PDE1A; phosphodiesterase 1A
5137 PDE1C; phosphodiesterase 1C
5138 PDE2A; phosphodiesterase 2A
5139 PDE3A; phosphodiesterase 3A
5140 PDE3B; phosphodiesterase 3B
5141 PDE4A; phosphodiesterase 4A
5142 PDE4B; phosphodiesterase 4B
5143 PDE4C; phosphodiesterase 4C
5144 PDE4D; phosphodiesterase 4D
5145 PDE6A; phosphodiesterase 6A
5146 PDE6C; phosphodiesterase 6C
5147 PDE6D; phosphodiesterase 6D
5148 PDE6G; phosphodiesterase 6G
5149 PDE6H; phosphodiesterase 6H
5150 PDE7A; phosphodiesterase 7A
5151 PDE8A; phosphodiesterase 8A
5152 PDE9A; phosphodiesterase 9A
5153 PDE1B; phosphodiesterase 1B
5158 PDE6B; phosphodiesterase 6B
5167 ENPP1; ectonucleotide pyrophosphatase/phosphodiesterase 1
5169 ENPP3; ectonucleotide pyrophosphatase/phosphodiesterase 3
51816 ADA2; adenosine deaminase 2
5198 PFAS; phosphoribosylformylglycinamidine synthase
5236 PGM1; phosphoglucomutase 1
5313 PKLR; pyruvate kinase L/R
5315 PKM; pyruvate kinase M1/2
53343 NUDT9; nudix hydrolase 9
5471 PPAT; phosphoribosyl pyrophosphate amidotransferase
55276 PGM2; phosphoglucomutase 2
55811 ADCY10; adenylate cyclase 10
55821 ALLC; allantoicase
5631 PRPS1; phosphoribosyl pyrophosphate synthetase 1
5634 PRPS2; phosphoribosyl pyrophosphate synthetase 2
56953 NT5M; 5',3'-nucleotidase, mitochondrial
56985 ADPRM; ADP-ribose/CDP-alcohol diphosphatase, manganese dependent
58497 PRUNE1; prune exopolyphosphatase 1
6240 RRM1; ribonucleotide reductase catalytic subunit M1
6241 RRM2; ribonucleotide reductase regulatory subunit M2
646625 URAD; ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase
654364 NME1-NME2; NME1-NME2 readthrough
7498 XDH; xanthine dehydrogenase
84284 NTPCR; nucleoside-triphosphatase, cancer-related
84618 NT5C1A; 5'-nucleotidase, cytosolic IA
8622 PDE8B; phosphodiesterase 8B
8654 PDE5A; phosphodiesterase 5A
8833 GMPS; guanine monophosphate synthase
9060 PAPSS2; 3'-phosphoadenosine 5'-phosphosulfate synthase 2
9061 PAPSS1; 3'-phosphoadenosine 5'-phosphosulfate synthase 1
93034 NT5C1B; 5'-nucleotidase, cytosolic IB
953 ENTPD1; ectonucleoside triphosphate diphosphohydrolase 1
954 ENTPD2; ectonucleoside triphosphate diphosphohydrolase 2
955 ENTPD6; ectonucleoside triphosphate diphosphohydrolase 6
956 ENTPD3; ectonucleoside triphosphate diphosphohydrolase 3
957 ENTPD5; ectonucleoside triphosphate diphosphohydrolase 5 (inactive)
9583 ENTPD4; ectonucleoside triphosphate diphosphohydrolase 4
9615 GDA; guanine deaminase
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K01488 add; adenosine deaminase [EC:3.5.4.4]
K01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]
K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
K18532 AK6; adenylate kinase [EC:2.7.4.3]
K01587 PAICS; phosphoribosylaminoimidazole carboxylase / phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:4.1.1.21 6.3.2.6]
K08041 ADCY1; adenylate cyclase 1 [EC:4.6.1.1]
K08042 ADCY2; adenylate cyclase 2 [EC:4.6.1.1]
K18438 PDE10; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:3.1.4.17 3.1.4.35]
K08043 ADCY3; adenylate cyclase 3 [EC:4.6.1.1]
K08045 ADCY5; adenylate cyclase 5 [EC:4.6.1.1]
K13987 NUDT5; ADP-sugar pyrophosphatase / 8-oxo-dGDP phosphatase / ADP-D-ribose pyrophosphorylase [EC:3.6.1.13 3.6.1.58 2.7.7.96]
K08046 ADCY6; adenylate cyclase 6 [EC:4.6.1.1]
K08047 ADCY7; adenylate cyclase 7 [EC:4.6.1.1]
K08048 ADCY8; adenylate cyclase 8 [EC:4.6.1.1]
K08049 ADCY9; adenylate cyclase 9 [EC:4.6.1.1]
K24242 NT5C3; cytosolic 5'-nucleotidase 3 [EC:3.1.3.5 3.1.3.-]
K00939 adk; adenylate kinase [EC:2.7.4.3]
K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
K12304 CANT1; soluble calcium-activated nucleotidase 1 [EC:3.6.1.6]
K16855 NUDT16; U8 snoRNA-decapping enzyme [EC:3.6.1.62 3.6.1.64]
K00856 E2.7.1.20; adenosine kinase [EC:2.7.1.20]
K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
K00939 adk; adenylate kinase [EC:2.7.4.3]
K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
K00893 DCK; deoxycitidine kinase [EC:2.7.1.74]
K00904 DGUOK; deoxyguanosine kinase [EC:2.7.1.113]
K08044 ADCY4; adenylate cyclase 4 [EC:4.6.1.1]
K00939 adk; adenylate kinase [EC:2.7.4.3]
K00939 adk; adenylate kinase [EC:2.7.4.3]
K00939 adk; adenylate kinase [EC:2.7.4.3]
K18533 AK9; adenylate/nucleoside-diphosphate kinase [EC:2.7.4.3 2.7.4.6]
K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
K01522 FHIT; bis(5'-adenosyl)-triphosphatase [EC:3.6.1.29]
K18424 ENPP4; ectonucleotide pyrophosphatase/phosphodiesterase family member 4 [EC:3.6.1.29]
K01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]
K11787 GART; phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.4.13 2.1.2.2 6.3.3.1]
K00939 adk; adenylate kinase [EC:2.7.4.3]
K01490 AMPD; AMP deaminase [EC:3.5.4.6]
K01490 AMPD; AMP deaminase [EC:3.5.4.6]
K18436 PDE7; high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7 [EC:3.1.4.53]
K01490 AMPD; AMP deaminase [EC:3.5.4.6]
K00364 E1.7.1.7; GMP reductase [EC:1.7.1.7]
K12318 GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
K12318 GUCY1A; guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
K12319 GUCY1B; guanylate cyclase soluble subunit beta [EC:4.6.1.2]
K12320 GUCY2C; heat-stable enterotoxin receptor [EC:4.6.1.2]
K12322 GUCY2F; guanylate cyclase 2F [EC:4.6.1.2]
K00942 E2.7.4.8; guanylate kinase [EC:2.7.4.8]
K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
K12321 GUCY2D_E; guanylate cyclase 2D/E [EC:4.6.1.2]
K01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]
K01518 NUDT2; bis(5'-nucleosidyl)-tetraphosphatase [EC:3.6.1.17]
K00760 hprT; hypoxanthine phosphoribosyltransferase [EC:2.4.2.8]
K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
K01519 ITPA; inosine triphosphate pyrophosphatase [EC:3.6.1.-]
K21138 HDDC3; guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [EC:3.1.7.2]
K01510 ENTPD1_3_8; apyrase [EC:3.6.1.5]
K00939 adk; adenylate kinase [EC:2.7.4.3]
K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
K03783 punA; purine-nucleoside phosphorylase [EC:2.4.2.1]
K12323 ANPRA; atrial natriuretic peptide receptor A [EC:4.6.1.2]
K12324 ANPRB; atrial natriuretic peptide receptor B [EC:4.6.1.2]
K19970 NT5E; 5'-nucleotidase [EC:3.1.3.5]
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K00944 AK3; nucleoside-triphosphate--adenylate kinase [EC:2.7.4.10]
K13298 PDE11; dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11 [EC:3.1.4.17 3.1.4.35]
K24242 NT5C3; cytosolic 5'-nucleotidase 3 [EC:3.1.3.5 3.1.3.-]
K00364 E1.7.1.7; GMP reductase [EC:1.7.1.7]
K13755 PDE1; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase [EC:3.1.4.17]
K13755 PDE1; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase [EC:3.1.4.17]
K18283 PDE2A; cGMP-dependent 3',5'-cyclic phosphodiesterase [EC:3.1.4.17]
K19021 PDE3A; cGMP-inhibited 3',5'-cyclic phosphodiesterase A [EC:3.1.4.17]
K13296 PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B [EC:3.1.4.17]
K13293 PDE4; cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
K13293 PDE4; cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
K13293 PDE4; cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
K13293 PDE4; cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
K08718 PDE6A; rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha [EC:3.1.4.35]
K13757 PDE6C; cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' [EC:3.1.4.35]
K13758 PDE6D; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta
K13759 PDE6G; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma
K13760 PDE6H; retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma
K18436 PDE7; high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7 [EC:3.1.4.53]
K18437 PDE8; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:3.1.4.53]
K13761 PDE9; high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9 [EC:3.1.4.35]
K13755 PDE1; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase [EC:3.1.4.17]
K13756 PDE6B; rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta [EC:3.1.4.35]
K01513 ENPP1_3; ectonucleotide pyrophosphatase/phosphodiesterase family member 1/3 [EC:3.1.4.1 3.6.1.9]
K01513 ENPP1_3; ectonucleotide pyrophosphatase/phosphodiesterase family member 1/3 [EC:3.1.4.1 3.6.1.9]
K19572 CECR1; adenosine deaminase CECR1 [EC:3.5.4.4]
K01952 PFAS; phosphoribosylformylglycinamidine synthase [EC:6.3.5.3]
K01835 pgm; phosphoglucomutase [EC:5.4.2.2]
K12406 PKLR; pyruvate kinase isozymes R/L [EC:2.7.1.40]
K00873 PK; pyruvate kinase [EC:2.7.1.40]
K13988 NUDT9; ADP-ribose pyrophosphatase [EC:3.6.1.13]
K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
K15779 PGM2; phosphoglucomutase / phosphopentomutase [EC:5.4.2.2 5.4.2.7]
K11265 ADCY10; adenylate cyclase 10 [EC:4.6.1.1]
K01477 alc; allantoicase [EC:3.5.3.4]
K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
K01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]
K01517 ADPRM; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [EC:3.6.1.13 3.6.1.16 3.6.1.53]
K01514 PRUNE; exopolyphosphatase [EC:3.6.1.11]
K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
K13485 PRHOXNB; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [EC:4.1.1.97]
K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
K00106 XDH; xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2]
K06928 NTPCR; nucleoside-triphosphatase [EC:3.6.1.15]
K01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]
K18437 PDE8; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:3.1.4.53]
K13762 PDE5; cGMP-specific 3',5'-cyclic phosphodiesterase [EC:3.1.4.35]
K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
K13811 PAPSS; 3'-phosphoadenosine 5'-phosphosulfate synthase [EC:2.7.7.4 2.7.1.25]
K13811 PAPSS; 3'-phosphoadenosine 5'-phosphosulfate synthase [EC:2.7.7.4 2.7.1.25]
K01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]
K01510 ENTPD1_3_8; apyrase [EC:3.6.1.5]
K01509 ENTPD2; adenosinetriphosphatase [EC:3.6.1.-]
K01511 ENTPD5_6; ectonucleoside triphosphate diphosphohydrolase 5/6 [EC:3.6.1.6]
K01510 ENTPD1_3_8; apyrase [EC:3.6.1.5]
K01511 ENTPD5_6; ectonucleoside triphosphate diphosphohydrolase 5/6 [EC:3.6.1.6]
K12305 ENTPD4; ectonucleoside triphosphate diphosphohydrolase 4 [EC:3.6.1.6]
K01487 E3.5.4.3; guanine deaminase [EC:3.5.4.3]
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00240 Pyrimidine metabolism [PATH:hsa00240]
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09105 Amino acid metabolism
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09106 Metabolism of other amino acids
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09107 Glycan biosynthesis and metabolism
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09108 Metabolism of cofactors and vitamins
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09109 Metabolism of terpenoids and polyketides
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09110 Biosynthesis of other secondary metabolites
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09111 Xenobiotics biodegradation and metabolism
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09112 Not included in regular maps
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09120 Genetic Information Processing
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09130 Environmental Information Processing
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09140 Cellular Processes
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09150 Organismal Systems
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09151 Immune system
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09152 Endocrine system
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04911 Insulin secretion [PATH:hsa04911]
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04910 Insulin signaling pathway [PATH:hsa04910]
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10000 AKT3; AKT serine/threonine kinase 3
10211 FLOT1; flotillin 1
10580 SORBS1; sorbin and SH3 domain containing 1
10603 SH2B2; SH2B adaptor protein 2
10891 PPARGC1A; PPARG coactivator 1 alpha
122809 SOCS4; suppressor of cytokine signaling 4
1398 CRK; CRK proto-oncogene, adaptor protein
1399 CRKL; CRK like proto-oncogene, adaptor protein
163688 CALML6; calmodulin like 6
1977 EIF4E; eukaryotic translation initiation factor 4E
1978 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
2002 ELK1; ETS transcription factor ELK1
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
2194 FASN; fatty acid synthase
2203 FBP1; fructose-bisphosphatase 1
2308 FOXO1; forkhead box O1
2319 FLOT2; flotillin 2
23265 EXOC7; exocyst complex component 7
23433 RHOQ; ras homolog family member Q
2475 MTOR; mechanistic target of rapamycin kinase
253314 EIF4E1B; eukaryotic translation initiation factor 4E family member 1B
2538 G6PC1; glucose-6-phosphatase catalytic subunit 1
25759 SHC2; SHC adaptor protein 2
2645 GCK; glucokinase
2872 MKNK2; MAPK interacting serine/threonine kinase 2
2885 GRB2; growth factor receptor bound protein 2
2889 RAPGEF1; Rap guanine nucleotide exchange factor 1
2932 GSK3B; glycogen synthase kinase 3 beta
2997 GYS1; glycogen synthase 1
2998 GYS2; glycogen synthase 2
3098 HK1; hexokinase 1
3099 HK2; hexokinase 2
31 ACACA; acetyl-CoA carboxylase alpha
3101 HK3; hexokinase 3
32 ACACB; acetyl-CoA carboxylase beta
3265 HRAS; HRas proto-oncogene, GTPase
3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
3630 INS; insulin
3632 INPP5A; inositol polyphosphate-5-phosphatase A
3636 INPPL1; inositol polyphosphate phosphatase like 1
3643 INSR; insulin receptor
3667 IRS1; insulin receptor substrate 1
369 ARAF; A-Raf proto-oncogene, serine/threonine kinase
3845 KRAS; KRAS proto-oncogene, GTPase
3991 LIPE; lipase E, hormone sensitive type
399694 SHC4; SHC adaptor protein 4
4893 NRAS; NRAS proto-oncogene, GTPase
5105 PCK1; phosphoenolpyruvate carboxykinase 1
5106 PCK2; phosphoenolpyruvate carboxykinase 2, mitochondrial
5140 PDE3B; phosphodiesterase 3B
51422 PRKAG2; protein kinase AMP-activated non-catalytic subunit gamma 2
5170 PDPK1; 3-phosphoinositide dependent protein kinase 1
51806 CALML5; calmodulin like 5
5255 PHKA1; phosphorylase kinase regulatory subunit alpha 1
5256 PHKA2; phosphorylase kinase regulatory subunit alpha 2
5257 PHKB; phosphorylase kinase regulatory subunit beta
5260 PHKG1; phosphorylase kinase catalytic subunit gamma 1
5261 PHKG2; phosphorylase kinase catalytic subunit gamma 2
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
5313 PKLR; pyruvate kinase L/R
53358 SHC3; SHC adaptor protein 3
53632 PRKAG3; protein kinase AMP-activated non-catalytic subunit gamma 3
5499 PPP1CA; protein phosphatase 1 catalytic subunit alpha
5500 PPP1CB; protein phosphatase 1 catalytic subunit beta
5501 PPP1CC; protein phosphatase 1 catalytic subunit gamma
5506 PPP1R3A; protein phosphatase 1 regulatory subunit 3A
5507 PPP1R3C; protein phosphatase 1 regulatory subunit 3C
5509 PPP1R3D; protein phosphatase 1 regulatory subunit 3D
5562 PRKAA1; protein kinase AMP-activated catalytic subunit alpha 1
5563 PRKAA2; protein kinase AMP-activated catalytic subunit alpha 2
5564 PRKAB1; protein kinase AMP-activated non-catalytic subunit beta 1
5565 PRKAB2; protein kinase AMP-activated non-catalytic subunit beta 2
5566 PRKACA; protein kinase cAMP-activated catalytic subunit alpha
5567 PRKACB; protein kinase cAMP-activated catalytic subunit beta
5568 PRKACG; protein kinase cAMP-activated catalytic subunit gamma
5571 PRKAG1; protein kinase AMP-activated non-catalytic subunit gamma 1
5573 PRKAR1A; protein kinase cAMP-dependent type I regulatory subunit alpha
5575 PRKAR1B; protein kinase cAMP-dependent type I regulatory subunit beta
5576 PRKAR2A; protein kinase cAMP-dependent type II regulatory subunit alpha
5577 PRKAR2B; protein kinase cAMP-dependent type II regulatory subunit beta
5584 PRKCI; protein kinase C iota
5590 PRKCZ; protein kinase C zeta
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
5599 MAPK8; mitogen-activated protein kinase 8
5601 MAPK9; mitogen-activated protein kinase 9
5602 MAPK10; mitogen-activated protein kinase 10
5604 MAP2K1; mitogen-activated protein kinase kinase 1
5605 MAP2K2; mitogen-activated protein kinase kinase 2
572 BAD; BCL2 associated agonist of cell death
57521 RPTOR; regulatory associated protein of MTOR complex 1
5770 PTPN1; protein tyrosine phosphatase non-receptor type 1
57818 G6PC2; glucose-6-phosphatase catalytic subunit 2
5792 PTPRF; protein tyrosine phosphatase receptor type F
5834 PYGB; glycogen phosphorylase B
5836 PYGL; glycogen phosphorylase L
5837 PYGM; glycogen phosphorylase, muscle associated
5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
6009 RHEB; Ras homolog, mTORC1 binding
6194 RPS6; ribosomal protein S6
6198 RPS6KB1; ribosomal protein S6 kinase B1
6199 RPS6KB2; ribosomal protein S6 kinase B2
6464 SHC1; SHC adaptor protein 1
6517 SLC2A4; solute carrier family 2 member 4
6654 SOS1; SOS Ras/Rac guanine nucleotide exchange factor 1
6655 SOS2; SOS Ras/Rho guanine nucleotide exchange factor 2
6720 SREBF1; sterol regulatory element binding transcription factor 1
673 BRAF; B-Raf proto-oncogene, serine/threonine kinase
7248 TSC1; TSC complex subunit 1
7249 TSC2; TSC complex subunit 2
79660 PPP1R3B; protein phosphatase 1 regulatory subunit 3B
801 CALM1; calmodulin 1
80201 HKDC1; hexokinase domain containing 1
805 CALM2; calmodulin 2
808 CALM3; calmodulin 3
810 CALML3; calmodulin like 3
8471 IRS4; insulin receptor substrate 4
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
8569 MKNK1; MAPK interacting serine/threonine kinase 1
8651 SOCS1; suppressor of cytokine signaling 1
8660 IRS2; insulin receptor substrate 2
867 CBL; Cbl proto-oncogene
868 CBLB; Cbl proto-oncogene B
8789 FBP2; fructose-bisphosphatase 2
8835 SOCS2; suppressor of cytokine signaling 2
89801 PPP1R3F; protein phosphatase 1 regulatory subunit 3F
9021 SOCS3; suppressor of cytokine signaling 3
90673 PPP1R3E; protein phosphatase 1 regulatory subunit 3E
91860 CALML4; calmodulin like 4
92579 G6PC3; glucose-6-phosphatase catalytic subunit 3
9322 TRIP10; thyroid hormone receptor interactor 10
9470 EIF4E2; eukaryotic translation initiation factor 4E family member 2
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K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07192 FLOT; flotillin
K06086 SORBS1; sorbin and SH3 domain containing protein 1
K07193 SH2B; SH2B adapter protein 2
K07202 PPARGC1A; alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
K04697 SOCS4; suppressor of cytokine signaling 4
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K02183 CALM; calmodulin
K03259 EIF4E; translation initiation factor 4E
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
K04375 ELK1; ETS domain-containing protein Elk-1
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K00665 FASN; fatty acid synthase, animal type [EC:2.3.1.85]
K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
K07201 FOXO1; forkhead box protein O1
K07192 FLOT; flotillin
K07195 EXOC7; exocyst complex component 7
K07194 RHOQ; Ras homolog gene family, member Q
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K03259 EIF4E; translation initiation factor 4E
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K17447 SHC2; SHC-transforming protein 2
K12407 GCK; glucokinase [EC:2.7.1.2]
K04372 MKNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
K04364 GRB2; growth factor receptor-bound protein 2
K06277 RAPGEF1; Rap guanine nucleotide exchange factor 1
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K00693 GYS; glycogen synthase [EC:2.4.1.11]
K00693 GYS; glycogen synthase [EC:2.4.1.11]
K00844 HK; hexokinase [EC:2.7.1.1]
K00844 HK; hexokinase [EC:2.7.1.1]
K11262 ACACA; acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K00844 HK; hexokinase [EC:2.7.1.1]
K01946 ACACB; acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K02833 HRAS; GTPase HRas
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04526 INS; insulin
K01106 INPP5A; inositol polyphosphate 5-phosphatase INPP5A [EC:3.1.3.56]
K15909 SHIP2; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 [EC:3.1.3.86]
K04527 INSR; insulin receptor [EC:2.7.10.1]
K16172 IRS1; insulin receptor substrate 1
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K07827 KRAS; GTPase KRas
K07188 LIPE; hormone-sensitive lipase [EC:3.1.1.79]
K17449 SHC4; SHC-transforming protein 4
K07828 NRAS; GTPase NRas
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
K13296 PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B [EC:3.1.4.17]
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K02183 CALM; calmodulin
K07190 PHKA_B; phosphorylase kinase alpha/beta subunit
K07190 PHKA_B; phosphorylase kinase alpha/beta subunit
K07190 PHKA_B; phosphorylase kinase alpha/beta subunit
K00871 PHKG; phosphorylase kinase gamma subunit [EC:2.7.11.19]
K00871 PHKG; phosphorylase kinase gamma subunit [EC:2.7.11.19]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K12406 PKLR; pyruvate kinase isozymes R/L [EC:2.7.1.40]
K17448 SHC3; SHC-transforming protein 3
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
K07189 PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
K07189 PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
K07189 PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K04345 PKA; protein kinase A [EC:2.7.11.11]
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K04739 PRKAR; cAMP-dependent protein kinase regulator
K04739 PRKAR; cAMP-dependent protein kinase regulator
K04739 PRKAR; cAMP-dependent protein kinase regulator
K04739 PRKAR; cAMP-dependent protein kinase regulator
K06069 PRKCI; atypical protein kinase C iota type [EC:2.7.11.13]
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K02158 BAD; Bcl-2-antagonist of cell death
K07204 RAPTOR; regulatory associated protein of mTOR
K05696 PTPN1; tyrosine-protein phosphatase non-receptor type 1 [EC:3.1.3.48]
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K05695 PTPRF; receptor-type tyrosine-protein phosphatase F [EC:3.1.3.48]
K00688 PYG; glycogen phosphorylase [EC:2.4.1.1]
K00688 PYG; glycogen phosphorylase [EC:2.4.1.1]
K00688 PYG; glycogen phosphorylase [EC:2.4.1.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K07208 RHEB; Ras homolog enriched in brain
K02991 RP-S6e; small subunit ribosomal protein S6e
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K06279 SHC1; SHC-transforming protein 1
K07191 SLC2A4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K07197 SREBP1; sterol regulatory element-binding transcription factor 1
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K07206 TSC1; tuberous sclerosis 1
K07207 TSC2; tuberous sclerosis 2
K07189 PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
K02183 CALM; calmodulin
K00844 HK; hexokinase [EC:2.7.1.1]
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K02183 CALM; calmodulin
K17446 IRS4; insulin receptor substrate 4
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04372 MKNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
K04694 SOCS1; suppressor of cytokine signaling 1
K07187 IRS2; insulin receptor substrate 2
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K22517 CBLB; E3 ubiquitin-protein ligase CBL-B [EC:2.3.2.27]
K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
K04695 SOCS2; suppressor of cytokine signaling 2
K17453 PPP1R3F; protein phosphatase 1 regulatory subunit 3F
K04696 SOCS3; suppressor of cytokine signaling 3
K07189 PPP1R3; protein phosphatase 1 regulatory subunit 3A/B/C/D/E
K02183 CALM; calmodulin
K01084 G6PC; glucose-6-phosphatase [EC:3.1.3.9]
K07196 TRIP10; thyroid hormone receptor interactor 10
K03259 EIF4E; translation initiation factor 4E
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04922 Glucagon signaling pathway [PATH:hsa04922]
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04923 Regulation of lipolysis in adipocytes [PATH:hsa04923]
|
04920 Adipocytokine signaling pathway [PATH:hsa04920]
|
03320 PPAR signaling pathway [PATH:hsa03320]
|
04929 GnRH secretion [PATH:hsa04929]
|
04912 GnRH signaling pathway [PATH:hsa04912]
|
04913 Ovarian steroidogenesis [PATH:hsa04913]
|
04915 Estrogen signaling pathway [PATH:hsa04915]
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04914 Progesterone-mediated oocyte maturation [PATH:hsa04914]
|
04917 Prolactin signaling pathway [PATH:hsa04917]
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04921 Oxytocin signaling pathway [PATH:hsa04921]
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04926 Relaxin signaling pathway [PATH:hsa04926]
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04935 Growth hormone synthesis, secretion and action [PATH:hsa04935]
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04918 Thyroid hormone synthesis [PATH:hsa04918]
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04919 Thyroid hormone signaling pathway [PATH:hsa04919]
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04928 Parathyroid hormone synthesis, secretion and action [PATH:hsa04928]
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04916 Melanogenesis [PATH:hsa04916]
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04924 Renin secretion [PATH:hsa04924]
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04614 Renin-angiotensin system [PATH:hsa04614]
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04925 Aldosterone synthesis and secretion [PATH:hsa04925]
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04927 Cortisol synthesis and secretion [PATH:hsa04927]
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09153 Circulatory system
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09154 Digestive system
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09155 Excretory system
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09156 Nervous system
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09157 Sensory system
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09158 Development and regeneration
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09149 Aging
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09159 Environmental adaptation
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09160 Human Diseases
|
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09161 Cancer: overview
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09162 Cancer: specific types
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09163 Immune disease
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09164 Neurodegenerative disease
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09165 Substance dependence
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09166 Cardiovascular disease
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09167 Endocrine and metabolic disease
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04930 Type II diabetes mellitus [PATH:hsa04930]
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122809 SOCS4; suppressor of cytokine signaling 4
2475 MTOR; mechanistic target of rapamycin kinase
2645 GCK; glucokinase
3098 HK1; hexokinase 1
3099 HK2; hexokinase 2
3101 HK3; hexokinase 3
3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
3630 INS; insulin
3643 INSR; insulin receptor
3651 PDX1; pancreatic and duodenal homeobox 1
3667 IRS1; insulin receptor substrate 1
3767 KCNJ11; potassium inwardly rectifying channel subfamily J member 11
389692 MAFA; MAF bZIP transcription factor A
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
5313 PKLR; pyruvate kinase L/R
5315 PKM; pyruvate kinase M1/2
5580 PRKCD; protein kinase C delta
5581 PRKCE; protein kinase C epsilon
5590 PRKCZ; protein kinase C zeta
5594 MAPK1; mitogen-activated protein kinase 1
5595 MAPK3; mitogen-activated protein kinase 3
5599 MAPK8; mitogen-activated protein kinase 8
5601 MAPK9; mitogen-activated protein kinase 9
5602 MAPK10; mitogen-activated protein kinase 10
6514 SLC2A2; solute carrier family 2 member 2
6517 SLC2A4; solute carrier family 2 member 4
6833 ABCC8; ATP binding cassette subfamily C member 8
7124 TNF; tumor necrosis factor
773 CACNA1A; calcium voltage-gated channel subunit alpha1 A
774 CACNA1B; calcium voltage-gated channel subunit alpha1 B
775 CACNA1C; calcium voltage-gated channel subunit alpha1 C
776 CACNA1D; calcium voltage-gated channel subunit alpha1 D
777 CACNA1E; calcium voltage-gated channel subunit alpha1 E
80201 HKDC1; hexokinase domain containing 1
8471 IRS4; insulin receptor substrate 4
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
8651 SOCS1; suppressor of cytokine signaling 1
8660 IRS2; insulin receptor substrate 2
8835 SOCS2; suppressor of cytokine signaling 2
8913 CACNA1G; calcium voltage-gated channel subunit alpha1 G
9021 SOCS3; suppressor of cytokine signaling 3
9370 ADIPOQ; adiponectin, C1Q and collagen domain containing
|
K04697 SOCS4; suppressor of cytokine signaling 4
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K12407 GCK; glucokinase [EC:2.7.1.2]
K00844 HK; hexokinase [EC:2.7.1.1]
K00844 HK; hexokinase [EC:2.7.1.1]
K00844 HK; hexokinase [EC:2.7.1.1]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04526 INS; insulin
K04527 INSR; insulin receptor [EC:2.7.10.1]
K07594 IPF1; insulin promoter factor 1
K16172 IRS1; insulin receptor substrate 1
K05004 KCNJ11; potassium inwardly-rectifying channel subfamily J member 11
K07595 MAFA; transcription factor MAFA
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K12406 PKLR; pyruvate kinase isozymes R/L [EC:2.7.1.40]
K00873 PK; pyruvate kinase [EC:2.7.1.40]
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K07593 SLC2A2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
K07191 SLC2A4; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4
K05032 ABCC8; ATP-binding cassette subfamily C (CFTR/MRP) member 8
K03156 TNF; tumor necrosis factor superfamily, member 2
K04344 CACNA1A; voltage-dependent calcium channel P/Q type alpha-1A
K04849 CACNA1B; voltage-dependent calcium channel N type alpha-1B
K04850 CACNA1C; voltage-dependent calcium channel L type alpha-1C
K04851 CACNA1D; voltage-dependent calcium channel L type alpha-1D
K04852 CACNA1E; voltage-dependent calcium channel R type alpha-1E
K00844 HK; hexokinase [EC:2.7.1.1]
K17446 IRS4; insulin receptor substrate 4
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04694 SOCS1; suppressor of cytokine signaling 1
K07187 IRS2; insulin receptor substrate 2
K04695 SOCS2; suppressor of cytokine signaling 2
K04854 CACNA1G; voltage-dependent calcium channel T type alpha-1G
K04696 SOCS3; suppressor of cytokine signaling 3
K07296 ADIPOQ; adiponectin
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04940 Type I diabetes mellitus [PATH:hsa04940]
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04950 Maturity onset diabetes of the young [PATH:hsa04950]
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168620 BHLHA15; basic helix-loop-helix family member a15
222546 RFX6; regulatory factor X6
2494 NR5A2; nuclear receptor subfamily 5 group A member 2
2645 GCK; glucokinase
3087 HHEX; hematopoietically expressed homeobox
3110 MNX1; motor neuron and pancreas homeobox 1
3170 FOXA2; forkhead box A2
3171 FOXA3; forkhead box A3
3172 HNF4A; hepatocyte nuclear factor 4 alpha
3174 HNF4G; hepatocyte nuclear factor 4 gamma
3175 ONECUT1; one cut homeobox 1
3280 HES1; hes family bHLH transcription factor 1
3375 IAPP; islet amyloid polypeptide
3630 INS; insulin
3651 PDX1; pancreatic and duodenal homeobox 1
389692 MAFA; MAF bZIP transcription factor A
4760 NEUROD1; neuronal differentiation 1
4821 NKX2-2; NK2 homeobox 2
4825 NKX6-1; NK6 homeobox 1
50674 NEUROG3; neurogenin 3
5078 PAX4; paired box 4
5080 PAX6; paired box 6
5313 PKLR; pyruvate kinase L/R
6514 SLC2A2; solute carrier family 2 member 2
6927 HNF1A; HNF1 homeobox A
6928 HNF1B; HNF1 homeobox B
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K08040 BHLHB8; class B basic helix-loop-helix protein 8
K19521 RFX6; regulatory factor X 6
K08027 NR5A2; nuclear receptor subfamily 5 group A member 2
K12407 GCK; glucokinase [EC:2.7.1.2]
K08024 HHEX; homeobox protein HEX
K08025 HLXB9; homeobox protein HB9
K08035 FOXA2; forkhead box protein A2, hepatocyte nuclear factor 3-beta
K08038 FOXA3; forkhead box protein A3, hepatocyte nuclear factor 3-gamma
K07292 NR2A1; hepatocyte nuclear factor 4-alpha
K08037 NR2A2; hepatocyte nuclear factor 4-gamma
K08026 ONECUT1; one cut domain, family member 1 (hepatocyte nuclear factor 6)
K06054 HES1; hairy and enhancer of split 1
K08039 IAPP; islet amyloid polypeptide
K04526 INS; insulin
K07594 IPF1; insulin promoter factor 1
K07595 MAFA; transcription factor MAFA
K08033 NEUROD1; neurogenic differentiation factor 1
K08029 NKX2-2; homeobox protein Nkx-2.2
K08030 NKX6-1; homeobox protein Nkx-6.1
K08028 NEUROG3; neurogenin 3
K08032 PAX4; paired box protein 4
K08031 PAX6; paired box protein 6
K12406 PKLR; pyruvate kinase isozymes R/L [EC:2.7.1.40]
K07593 SLC2A2; MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 2
K08036 TCF1; transcription factor 1, hepatocyte nuclear factor 1-alpha
K08034 TCF2; transcription factor 2, hepatocyte nuclear factor 1-beta
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04932 Non-alcoholic fatty liver disease [PATH:hsa04932]
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10000 AKT3; AKT serine/threonine kinase 3
10018 BCL2L11; BCL2 like 11
100532726 NDUFC2-KCTD14; NDUFC2-KCTD14 readthrough
10062 NR1H3; nuclear receptor subfamily 1 group H member 3
1050 CEBPA; CCAAT enhancer binding protein alpha
10975 UQCR11; ubiquinol-cytochrome c reductase, complex III subunit XI
125965 COX6B2; cytochrome c oxidase subunit 6B2
126328 NDUFA11; NADH:ubiquinone oxidoreductase subunit A11
1327 COX4I1; cytochrome c oxidase subunit 4I1
1329 COX5B; cytochrome c oxidase subunit 5B
1337 COX6A1; cytochrome c oxidase subunit 6A1
1339 COX6A2; cytochrome c oxidase subunit 6A2
1340 COX6B1; cytochrome c oxidase subunit 6B1
1345 COX6C; cytochrome c oxidase subunit 6C
1346 COX7A1; cytochrome c oxidase subunit 7A1
1347 COX7A2; cytochrome c oxidase subunit 7A2
1349 COX7B; cytochrome c oxidase subunit 7B
1350 COX7C; cytochrome c oxidase subunit 7C
1351 COX8A; cytochrome c oxidase subunit 8A
1537 CYC1; cytochrome c1
1571 CYP2E1; cytochrome P450 family 2 subfamily E member 1
1649 DDIT3; DNA damage inducible transcript 3
170712 COX7B2; cytochrome c oxidase subunit 7B2
1965 EIF2S1; eukaryotic translation initiation factor 2 subunit alpha
207 AKT1; AKT serine/threonine kinase 1
208 AKT2; AKT serine/threonine kinase 2
2081 ERN1; endoplasmic reticulum to nucleus signaling 1
22877 MLXIP; MLX interacting protein
2353 FOS; Fos proto-oncogene, AP-1 transcription factor subunit
27089 UQCRQ; ubiquinol-cytochrome c reductase complex III subunit VII
2931 GSK3A; glycogen synthase kinase 3 alpha
2932 GSK3B; glycogen synthase kinase 3 beta
29796 UQCR10; ubiquinol-cytochrome c reductase, complex III subunit X
341947 COX8C; cytochrome c oxidase subunit 8C
355 FAS; Fas cell surface death receptor
3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
3552 IL1A; interleukin 1 alpha
3553 IL1B; interleukin 1 beta
356 FASLG; Fas ligand
3569 IL6; interleukin 6
3570 IL6R; interleukin 6 receptor
3576 CXCL8; C-X-C motif chemokine ligand 8
3630 INS; insulin
3643 INSR; insulin receptor
3667 IRS1; insulin receptor substrate 1
3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
374291 NDUFS7; NADH:ubiquinone oxidoreductase core subunit S7
3952 LEP; leptin
3953 LEPR; leptin receptor
4217 MAP3K5; mitogen-activated protein kinase kinase kinase 5
4296 MAP3K11; mitogen-activated protein kinase kinase kinase 11
440567 UQCRHL; ubiquinol-cytochrome c reductase hinge protein like
4512 COX1; cytochrome c oxidase subunit I
4513 COX2; cytochrome c oxidase subunit II
4514 COX3; cytochrome c oxidase subunit III
4519 CYTB; cytochrome b
468 ATF4; activating transcription factor 4
4694 NDUFA1; NADH:ubiquinone oxidoreductase subunit A1
4695 NDUFA2; NADH:ubiquinone oxidoreductase subunit A2
4696 NDUFA3; NADH:ubiquinone oxidoreductase subunit A3
4697 NDUFA4; NDUFA4 mitochondrial complex associated
4698 NDUFA5; NADH:ubiquinone oxidoreductase subunit A5
4700 NDUFA6; NADH:ubiquinone oxidoreductase subunit A6
4701 NDUFA7; NADH:ubiquinone oxidoreductase subunit A7
4702 NDUFA8; NADH:ubiquinone oxidoreductase subunit A8
4704 NDUFA9; NADH:ubiquinone oxidoreductase subunit A9
4705 NDUFA10; NADH:ubiquinone oxidoreductase subunit A10
4706 NDUFAB1; NADH:ubiquinone oxidoreductase subunit AB1
4707 NDUFB1; NADH:ubiquinone oxidoreductase subunit B1
4708 NDUFB2; NADH:ubiquinone oxidoreductase subunit B2
4709 NDUFB3; NADH:ubiquinone oxidoreductase subunit B3
4710 NDUFB4; NADH:ubiquinone oxidoreductase subunit B4
4711 NDUFB5; NADH:ubiquinone oxidoreductase subunit B5
4712 NDUFB6; NADH:ubiquinone oxidoreductase subunit B6
4713 NDUFB7; NADH:ubiquinone oxidoreductase subunit B7
4714 NDUFB8; NADH:ubiquinone oxidoreductase subunit B8
4715 NDUFB9; NADH:ubiquinone oxidoreductase subunit B9
4716 NDUFB10; NADH:ubiquinone oxidoreductase subunit B10
4717 NDUFC1; NADH:ubiquinone oxidoreductase subunit C1
4718 NDUFC2; NADH:ubiquinone oxidoreductase subunit C2
4719 NDUFS1; NADH:ubiquinone oxidoreductase core subunit S1
4720 NDUFS2; NADH:ubiquinone oxidoreductase core subunit S2
4722 NDUFS3; NADH:ubiquinone oxidoreductase core subunit S3
4723 NDUFV1; NADH:ubiquinone oxidoreductase core subunit V1
4724 NDUFS4; NADH:ubiquinone oxidoreductase subunit S4
4725 NDUFS5; NADH:ubiquinone oxidoreductase subunit S5
4726 NDUFS6; NADH:ubiquinone oxidoreductase subunit S6
4728 NDUFS8; NADH:ubiquinone oxidoreductase core subunit S8
4729 NDUFV2; NADH:ubiquinone oxidoreductase core subunit V2
4731 NDUFV3; NADH:ubiquinone oxidoreductase subunit V3
4790 NFKB1; nuclear factor kappa B subunit 1
51079 NDUFA13; NADH:ubiquinone oxidoreductase subunit A13
51085 MLXIPL; MLX interacting protein like
51094 ADIPOR1; adiponectin receptor 1
51422 PRKAG2; protein kinase AMP-activated non-catalytic subunit gamma 2
5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
5313 PKLR; pyruvate kinase L/R
53632 PRKAG3; protein kinase AMP-activated non-catalytic subunit gamma 3
54205 CYCS; cytochrome c, somatic
54539 NDUFB11; NADH:ubiquinone oxidoreductase subunit B11
5465 PPARA; peroxisome proliferator activated receptor alpha
5562 PRKAA1; protein kinase AMP-activated catalytic subunit alpha 1
5563 PRKAA2; protein kinase AMP-activated catalytic subunit alpha 2
5564 PRKAB1; protein kinase AMP-activated non-catalytic subunit beta 1
5565 PRKAB2; protein kinase AMP-activated non-catalytic subunit beta 2
5571 PRKAG1; protein kinase AMP-activated non-catalytic subunit gamma 1
55967 NDUFA12; NADH:ubiquinone oxidoreductase subunit A12
5599 MAPK8; mitogen-activated protein kinase 8
5601 MAPK9; mitogen-activated protein kinase 9
5602 MAPK10; mitogen-activated protein kinase 10
56901 NDUFA4L2; NDUFA4 mitochondrial complex associated like 2
581 BAX; BCL2 associated X, apoptosis regulator
5879 RAC1; Rac family small GTPase 1
5970 RELA; RELA proto-oncogene, NF-kB subunit
6256 RXRA; retinoid X receptor alpha
637 BID; BH3 interacting domain death agonist
6389 SDHA; succinate dehydrogenase complex flavoprotein subunit A
6390 SDHB; succinate dehydrogenase complex iron sulfur subunit B
6391 SDHC; succinate dehydrogenase complex subunit C
6392 SDHD; succinate dehydrogenase complex subunit D
6720 SREBF1; sterol regulatory element binding transcription factor 1
6945 MLX; MAX dimerization protein MLX
7040 TGFB1; transforming growth factor beta 1
7124 TNF; tumor necrosis factor
7132 TNFRSF1A; TNF receptor superfamily member 1A
7186 TRAF2; TNF receptor associated factor 2
7381 UQCRB; ubiquinol-cytochrome c reductase binding protein
7384 UQCRC1; ubiquinol-cytochrome c reductase core protein 1
7385 UQCRC2; ubiquinol-cytochrome c reductase core protein 2
7386 UQCRFS1; ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
7388 UQCRH; ubiquinol-cytochrome c reductase hinge protein
7494 XBP1; X-box binding protein 1
79602 ADIPOR2; adiponectin receptor 2
836 CASP3; caspase 3
83737 ITCH; itchy E3 ubiquitin protein ligase
840 CASP7; caspase 7
841 CASP8; caspase 8
84701 COX4I2; cytochrome c oxidase subunit 4I2
8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
8660 IRS2; insulin receptor substrate 2
9021 SOCS3; suppressor of cytokine signaling 3
9167 COX7A2L; cytochrome c oxidase subunit 7A2 like
9370 ADIPOQ; adiponectin, C1Q and collagen domain containing
9377 COX5A; cytochrome c oxidase subunit 5A
9451 EIF2AK3; eukaryotic translation initiation factor 2 alpha kinase 3
998 CDC42; cell division cycle 42
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K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K16341 BCL2L11; Bcl-2-like protein 11
K03968 NDUFC2; NADH dehydrogenase (ubiquinone) 1 subunit C2
K08536 NR1H3; liver X receptor alpha
K09055 CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha
K00420 QCR10; ubiquinol-cytochrome c reductase subunit 10
K02267 COX6B; cytochrome c oxidase subunit 6b
K03956 NDUFA11; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 11
K02263 COX4; cytochrome c oxidase subunit 4
K02265 COX5B; cytochrome c oxidase subunit 5b
K02266 COX6A; cytochrome c oxidase subunit 6a
K02266 COX6A; cytochrome c oxidase subunit 6a
K02267 COX6B; cytochrome c oxidase subunit 6b
K02268 COX6C; cytochrome c oxidase subunit 6c
K02270 COX7A; cytochrome c oxidase subunit 7a
K02270 COX7A; cytochrome c oxidase subunit 7a
K02271 COX7B; cytochrome c oxidase subunit 7b
K02272 COX7C; cytochrome c oxidase subunit 7c
K02273 COX8; cytochrome c oxidase subunit 8
K00413 CYC1; ubiquinol-cytochrome c reductase cytochrome c1 subunit
K07415 CYP2E1; cytochrome P450 family 2 subfamily E1 [EC:1.14.14.-]
K04452 DDIT3; DNA damage-inducible transcript 3
K02271 COX7B; cytochrome c oxidase subunit 7b
K03237 EIF2S1; translation initiation factor 2 subunit 1
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K08852 ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
K09113 MLX; MAX-like protein X
K04379 FOS; proto-oncogene protein c-fos
K00418 QCR8; ubiquinol-cytochrome c reductase subunit 8
K08822 GSK3A; glycogen synthase kinase 3 alpha [EC:2.7.11.26]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K00419 QCR9; ubiquinol-cytochrome c reductase subunit 9
K02273 COX8; cytochrome c oxidase subunit 8
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04383 IL1A; interleukin 1 alpha
K04519 IL1B; interleukin 1 beta
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K05405 IL6; interleukin 6
K05055 IL6R; interleukin 6 receptor
K10030 IL8; interleukin 8
K04526 INS; insulin
K04527 INSR; insulin receptor [EC:2.7.10.1]
K16172 IRS1; insulin receptor substrate 1
K04448 JUN; transcription factor AP-1
K03940 NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:7.1.1.2]
K05424 LEP; leptin
K05062 LEPR; leptin receptor
K04426 MAP3K5; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04419 MAP3K11; mitogen-activated protein kinase kinase kinase 11 [EC:2.7.11.25]
K00416 QCR6; ubiquinol-cytochrome c reductase subunit 6
K02256 COX1; cytochrome c oxidase subunit 1 [EC:7.1.1.9]
K02261 COX2; cytochrome c oxidase subunit 2
K02262 COX3; cytochrome c oxidase subunit 3
K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit
K04374 ATF4; cyclic AMP-dependent transcription factor ATF-4
K03945 NDUFA1; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 1
K03946 NDUFA2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2
K03947 NDUFA3; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 3
K03948 NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4
K03949 NDUFA5; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 5
K03950 NDUFA6; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6
K03951 NDUFA7; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7
K03952 NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 8
K03953 NDUFA9; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 9
K03954 NDUFA10; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10
K03955 NDUFAB1; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1, acyl-carrier protein
K03957 NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
K03958 NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
K03959 NDUFB3; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3
K03960 NDUFB4; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 4
K03961 NDUFB5; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5
K03962 NDUFB6; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6
K03963 NDUFB7; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7
K03964 NDUFB8; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8
K03965 NDUFB9; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9
K03966 NDUFB10; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10
K03967 NDUFC1; NADH dehydrogenase (ubiquinone) 1 subunit C1
K03968 NDUFC2; NADH dehydrogenase (ubiquinone) 1 subunit C2
K03934 NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:7.1.1.2]
K03935 NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:7.1.1.2]
K03936 NDUFS3; NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:7.1.1.2]
K03942 NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:7.1.1.2]
K03937 NDUFS4; NADH dehydrogenase (ubiquinone) Fe-S protein 4
K03938 NDUFS5; NADH dehydrogenase (ubiquinone) Fe-S protein 5
K03939 NDUFS6; NADH dehydrogenase (ubiquinone) Fe-S protein 6
K03941 NDUFS8; NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:7.1.1.2]
K03943 NDUFV2; NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:7.1.1.2]
K03944 NDUFV3; NADH dehydrogenase (ubiquinone) flavoprotein 3
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K11353 NDUFA13; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13
K09113 MLX; MAX-like protein X
K07297 ADIPOR; adiponectin receptor
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K12406 PKLR; pyruvate kinase isozymes R/L [EC:2.7.1.40]
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K08738 CYC; cytochrome c
K11351 NDUFB11; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11
K07294 NR1C1; peroxisome proliferator-activated receptor alpha
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07199 PRKAB; 5'-AMP-activated protein kinase, regulatory beta subunit
K07200 PRKAG; 5'-AMP-activated protein kinase, regulatory gamma subunit
K11352 NDUFA12; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 12
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K03948 NDUFA4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4
K02159 BAX; apoptosis regulator BAX
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K04735 RELA; transcription factor p65
K08524 RXRA; retinoid X receptor alpha
K04726 BID; BH3 interacting domain death agonist
K00234 SDHA; succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]
K00235 SDHB; succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1]
K00236 SDHC; succinate dehydrogenase (ubiquinone) cytochrome b560 subunit
K00237 SDHD; succinate dehydrogenase (ubiquinone) membrane anchor subunit
K07197 SREBP1; sterol regulatory element-binding transcription factor 1
K09113 MLX; MAX-like protein X
K13375 TGFB1; transforming growth factor beta-1
K03156 TNF; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A; tumor necrosis factor receptor superfamily member 1A
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K00417 QCR7; ubiquinol-cytochrome c reductase subunit 7
K00414 QCR1; ubiquinol-cytochrome c reductase core subunit 1
K00415 QCR2; ubiquinol-cytochrome c reductase core subunit 2
K00411 UQCRFS1; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
K00416 QCR6; ubiquinol-cytochrome c reductase subunit 6
K09027 XBP1; X box-binding protein 1
K07297 ADIPOR; adiponectin receptor
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K05632 ITCH; E3 ubiquitin-protein ligase Itchy [EC:2.3.2.26]
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K02263 COX4; cytochrome c oxidase subunit 4
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K07187 IRS2; insulin receptor substrate 2
K04696 SOCS3; suppressor of cytokine signaling 3
K02270 COX7A; cytochrome c oxidase subunit 7a
K07296 ADIPOQ; adiponectin
K02264 COX5A; cytochrome c oxidase subunit 5a
K08860 EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
K04393 CDC42; cell division control protein 42
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04931 Insulin resistance [PATH:hsa04931]
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04933 AGE-RAGE signaling pathway in diabetic complications [PATH:hsa04933]
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04934 Cushing syndrome [PATH:hsa04934]
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09171 Infectious disease: bacterial
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09172 Infectious disease: viral
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09174 Infectious disease: parasitic
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09175 Drug resistance: antimicrobial
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09176 Drug resistance: antineoplastic
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09180 Brite Hierarchies
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09190 Not Included in Pathway or Brite
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KEGG Orthology (KO) - Homo sapiens (human)