KEGG Orthology (KO) - Homo sapiens (human)

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     KO
 09100 Metabolism
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
 09140 Cellular Processes
 
 09150 Organismal Systems
 
 09160 Human Diseases
 
   09161 Cancer: overview
 
   09162 Cancer: specific types
 
   09163 Immune disease
 
   09164 Neurodegenerative disease
 
   09165 Substance dependence
 
   09166 Cardiovascular disease
 
   09167 Endocrine and metabolic disease
 
   09171 Infectious disease: bacterial
     05110 Vibrio cholerae infection [PATH:hsa05110]
     05120 Epithelial cell signaling in Helicobacter pylori infection [PATH:hsa05120]
     05130 Pathogenic Escherichia coli infection [PATH:hsa05130]
     05132 Salmonella infection [PATH:hsa05132]
       5420 PODXL; podocalyxin like
       5788 PTPRC; protein tyrosine phosphatase receptor type C
       5868 RAB5A; RAB5A, member RAS oncogene family
       5869 RAB5B; RAB5B, member RAS oncogene family
       5878 RAB5C; RAB5C, member RAS oncogene family
       5289 PIK3C3; phosphatidylinositol 3-kinase catalytic subunit type 3
       7879 RAB7A; RAB7A, member RAS oncogene family
       338382 RAB7B; RAB7B, member RAS oncogene family
       9842 PLEKHM1; pleckstrin homology and RUN domain containing M1
       55823 VPS11; VPS11 core subunit of CORVET and HOPS complexes
       64601 VPS16; VPS16 core subunit of CORVET and HOPS complexes
       57617 VPS18; VPS18 core subunit of CORVET and HOPS complexes
       65082 VPS33A; VPS33A core subunit of CORVET and HOPS complexes
       23339 VPS39; VPS39 subunit of HOPS complex
       27072 VPS41; VPS41 subunit of HOPS complex
       83547 RILP; Rab interacting lysosomal protein
       1778 DYNC1H1; dynein cytoplasmic 1 heavy chain 1
       79659 DYNC2H1; dynein cytoplasmic 2 heavy chain 1
       1780 DYNC1I1; dynein cytoplasmic 1 intermediate chain 1
       1781 DYNC1I2; dynein cytoplasmic 1 intermediate chain 2
       1783 DYNC1LI2; dynein cytoplasmic 1 light intermediate chain 2
       51143 DYNC1LI1; dynein cytoplasmic 1 light intermediate chain 1
       51626 DYNC2LI1; dynein cytoplasmic 2 light intermediate chain 1
       8655 DYNLL1; dynein light chain LC8-type 1
       140735 DYNLL2; dynein light chain LC8-type 2
       83658 DYNLRB1; dynein light chain roadblock-type 1
       83657 DYNLRB2; dynein light chain roadblock-type 2
       6993 DYNLT1; dynein light chain Tctex-type 1
       6990 DYNLT3; dynein light chain Tctex-type 3
       1639 DCTN1; dynactin subunit 1
       10540 DCTN2; dynactin subunit 2
       11258 DCTN3; dynactin subunit 3
       51164 DCTN4; dynactin subunit 4
       84516 DCTN5; dynactin subunit 5
       10671 DCTN6; dynactin subunit 6
       10121 ACTR1A; actin related protein 1A
       10120 ACTR1B; actin related protein 1B
       55860 ACTR10; actin related protein 10
       10376 TUBA1B; tubulin alpha 1b
       7277 TUBA4A; tubulin alpha 4a
       7278 TUBA3C; tubulin alpha 3c
       7846 TUBA1A; tubulin alpha 1a
       84790 TUBA1C; tubulin alpha 1c
       51807 TUBA8; tubulin alpha 8
       112714 TUBA3E; tubulin alpha 3e
       113457 TUBA3D; tubulin alpha 3d
       79861 TUBAL3; tubulin alpha like 3
       84617 TUBB6; tubulin beta 6 class V
       203068 TUBB; tubulin beta class I
       81027 TUBB1; tubulin beta 1 class VI
       7280 TUBB2A; tubulin beta 2A class IIa
       10381 TUBB3; tubulin beta 3 class III
       10382 TUBB4A; tubulin beta 4A class IVa
       347688 TUBB8; tubulin beta 8 class VIII
       347733 TUBB2B; tubulin beta 2B class IIb
       10383 TUBB4B; tubulin beta 4B class IVb
       79443 FYCO1; FYVE and coiled-coil domain autophagy adaptor 1
       127829 ARL8A; ADP ribosylation factor like GTPase 8A
       55207 ARL8B; ADP ribosylation factor like GTPase 8B
       23207 PLEKHM2; pleckstrin homology and RUN domain containing M2
       3798 KIF5A; kinesin family member 5A
       3799 KIF5B; kinesin family member 5B
       3800 KIF5C; kinesin family member 5C
       147700 KLC3; kinesin light chain 3
       3831 KLC1; kinesin light chain 1
       64837 KLC2; kinesin light chain 2
       89953 KLC4; kinesin light chain 4
       64746 ACBD3; acyl-CoA binding domain containing 3
       387 RHOA; ras homolog family member A
       4074 M6PR; mannose-6-phosphate receptor, cation dependent
       9367 RAB9A; RAB9A, member RAS oncogene family
       51209 RAB9B; RAB9B, member RAS oncogene family
       9648 GCC2; GRIP and coiled-coil domain containing 2
       8677 STX10; syntaxin 10
       345456 PFN3; profilin 3
       5216 PFN1; profilin 1
       5217 PFN2; profilin 2
       375189 PFN4; profilin family member 4
       2316 FLNA; filamin A
       2318 FLNC; filamin C
       2317 FLNB; filamin B
       23265 EXOC7; exocyst complex component 7
       10640 EXOC5; exocyst complex component 5
       60412 EXOC4; exocyst complex component 4
       55770 EXOC2; exocyst complex component 2
       5898 RALA; RAS like proto-oncogene A
       71 ACTG1; actin gamma 1
       60 ACTB; actin beta
       6281 S100A10; S100 calcium binding protein A10
       302 ANXA2; annexin A2
       79026 AHNAK; AHNAK nucleoprotein
       113146 AHNAK2; AHNAK nucleoprotein 2
       57381 RHOJ; ras homolog family member J
       26084 ARHGEF26; Rho guanine nucleotide exchange factor 26
       391 RHOG; ras homolog family member G
       9844 ELMO1; engulfment and cell motility 1
       63916 ELMO2; engulfment and cell motility 2
       9475 ROCK2; Rho associated coiled-coil containing protein kinase 2
       4633 MYL2; myosin light chain 2
       4636 MYL5; myosin light chain 5
       58498 MYL7; myosin light chain 7
       10398 MYL9; myosin light chain 9
       93408 MYL10; myosin light chain 10
       103910 MYL12B; myosin light chain 12B
       10627 MYL12A; myosin light chain 12A
       29895 MYLPF; myosin light chain, phosphorylatable, fast skeletal muscle
       29109 FHOD1; formin homology 2 domain containing 1
       998 CDC42; cell division cycle 42
       5879 RAC1; Rac family small GTPase 1
       10787 NCKAP1; NCK associated protein 1
       3071 NCKAP1L; NCK associated protein 1 like
       23191 CYFIP1; cytoplasmic FMR1 interacting protein 1
       26999 CYFIP2; cytoplasmic FMR1 interacting protein 2
       10006 ABI1; abl interactor 1
       55845 BRK1; BRICK1 subunit of SCAR/WAVE actin nucleating complex
       10810 WASF3; WASP family member 3
       10097 ACTR2; actin related protein 2
       57180 ACTR3B; actin related protein 3B
       653857 ACTR3C; actin related protein 3C
       10096 ACTR3; actin related protein 3
       10095 ARPC1B; actin related protein 2/3 complex subunit 1B
       10552 ARPC1A; actin related protein 2/3 complex subunit 1A
       10109 ARPC2; actin related protein 2/3 complex subunit 2
       10094 ARPC3; actin related protein 2/3 complex subunit 3
       10093 ARPC4; actin related protein 2/3 complex subunit 4
       10092 ARPC5; actin related protein 2/3 complex subunit 5
       81873 ARPC5L; actin related protein 2/3 complex subunit 5 like
       5058 PAK1; p21 (RAC1) activated kinase 1
       5063 PAK3; p21 (RAC1) activated kinase 3
       4646 MYO6; myosin VI
       5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       5294 PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
       5288 PIK3C2G; phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
       5286 PIK3C2A; phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha
       5287 PIK3C2B; phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
       9265 CYTH3; cytohesin 3
       27128 CYTH4; cytohesin 4
       9266 CYTH2; cytohesin 2
       9267 CYTH1; cytohesin 1
       382 ARF6; ADP ribosylation factor 6
       375 ARF1; ADP ribosylation factor 1
       112574 SNX18; sorting nexin 18
       257364 SNX33; sorting nexin 33
       51429 SNX9; sorting nexin 9
       8976 WASL; WASP like actin nucleation promoting factor
       1785 DNM2; dynamin 2
       10333 TLR6; toll like receptor 6
       7097 TLR2; toll like receptor 2
       114609 TIRAP; TIR domain containing adaptor protein
       4615 MYD88; MYD88 innate immune signal transduction adaptor
       929 CD14; CD14 molecule
       7099 TLR4; toll like receptor 4
       23643 LY96; lymphocyte antigen 96
       7100 TLR5; toll like receptor 5
       54106 TLR9; toll like receptor 9
       3654 IRAK1; interleukin 1 receptor associated kinase 1
       51135 IRAK4; interleukin 1 receptor associated kinase 4
       7189 TRAF6; TNF receptor associated factor 6
       6885 MAP3K7; mitogen-activated protein kinase kinase kinase 7
       10454 TAB1; TGF-beta activated kinase 1 (MAP3K7) binding protein 1
       23118 TAB2; TGF-beta activated kinase 1 (MAP3K7) binding protein 2
       257397 TAB3; TGF-beta activated kinase 1 (MAP3K7) binding protein 3
       8517 IKBKG; inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
       1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
       3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
       4792 NFKBIA; NFKB inhibitor alpha
       4790 NFKB1; nuclear factor kappa B subunit 1
       5970 RELA; RELA proto-oncogene, NF-kB subunit
       10392 NOD1; nucleotide binding oligomerization domain containing 1
       3320 HSP90AA1; heat shock protein 90 alpha family class A member 1
       3326 HSP90AB1; heat shock protein 90 alpha family class B member 1
       7184 HSP90B1; heat shock protein 90 beta family member 1
       8767 RIPK2; receptor interacting serine/threonine kinase 2
       1434 CSE1L; chromosome segregation 1 like
       3836 KPNA1; karyopherin subunit alpha 1
       3839 KPNA3; karyopherin subunit alpha 3
       3840 KPNA4; karyopherin subunit alpha 4
       6188 RPS3; ribosomal protein S3
       3265 HRAS; HRas proto-oncogene, GTPase
       5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
       5604 MAP2K1; mitogen-activated protein kinase kinase 1
       5605 MAP2K2; mitogen-activated protein kinase kinase 2
       5594 MAPK1; mitogen-activated protein kinase 1
       5595 MAPK3; mitogen-activated protein kinase 3
       5606 MAP2K3; mitogen-activated protein kinase kinase 3
       5608 MAP2K6; mitogen-activated protein kinase kinase 6
       5600 MAPK11; mitogen-activated protein kinase 11
       6300 MAPK12; mitogen-activated protein kinase 12
       5603 MAPK13; mitogen-activated protein kinase 13
       1432 MAPK14; mitogen-activated protein kinase 14
       6416 MAP2K4; mitogen-activated protein kinase kinase 4
       5609 MAP2K7; mitogen-activated protein kinase kinase 7
       5599 MAPK8; mitogen-activated protein kinase 8
       5602 MAPK10; mitogen-activated protein kinase 10
       5601 MAPK9; mitogen-activated protein kinase 9
       2353 FOS; Fos proto-oncogene, AP-1 transcription factor subunit
       3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
       7124 TNF; tumor necrosis factor
       3553 IL1B; interleukin 1 beta
       3569 IL6; interleukin 6
       3576 CXCL8; C-X-C motif chemokine ligand 8
       1499 CTNNB1; catenin beta 1
       6932 TCF7; transcription factor 7
       83439 TCF7L1; transcription factor 7 like 1
       6934 TCF7L2; transcription factor 7 like 2
       51176 LEF1; lymphoid enhancer binding factor 1
       4609 MYC; MYC proto-oncogene, bHLH transcription factor
       5585 PKN1; protein kinase N1
       26263 FBXO22; F-box protein 22
       6500 SKP1; S-phase kinase associated protein 1
       7132 TNFRSF1A; TNF receptor superfamily member 1A
       7186 TRAF2; TNF receptor associated factor 2
       8717 TRADD; TNFRSF1A associated via death domain
       329 BIRC2; baculoviral IAP repeat containing 2
       330 BIRC3; baculoviral IAP repeat containing 3
       8737 RIPK1; receptor interacting serine/threonine kinase 1
       2597 GAPDH; glyceraldehyde-3-phosphate dehydrogenase
       8743 TNFSF10; TNF superfamily member 10
       8797 TNFRSF10A; TNF receptor superfamily member 10a
       8795 TNFRSF10B; TNF receptor superfamily member 10b
       8772 FADD; Fas associated via death domain
       841 CASP8; caspase 8
       11035 RIPK3; receptor interacting serine/threonine kinase 3
       581 BAX; BCL2 associated X, apoptosis regulator
       578 BAK1; BCL2 antagonist/killer 1
       54205 CYCS; cytochrome c, somatic
       596 BCL2; BCL2 apoptosis regulator
       836 CASP3; caspase 3
       840 CASP7; caspase 7
       388 RHOB; ras homolog family member B
       399 RHOH; ras homolog family member H
       6237 RRAS; RAS related
       207 AKT1; AKT serine/threonine kinase 1
       208 AKT2; AKT serine/threonine kinase 2
       10000 AKT3; AKT serine/threonine kinase 3
       197259 MLKL; mixed lineage kinase domain like pseudokinase
       7295 TXN; thioredoxin
       25828 TXN2; thioredoxin 2
       114548 NLRP3; NLR family pyrin domain containing 3
       4671 NAIP; NLR family apoptosis inhibitory protein
       58484 NLRC4; NLR family CARD domain containing 4
       29108 PYCARD; PYD and CARD domain containing
       834 CASP1; caspase 1
       3606 IL18; interleukin 18
       837 CASP4; caspase 4
       838 CASP5; caspase 5
       79792 GSDMD; gasdermin D
K06817 PODXL; podocalyxin-like
K06478 PTPRC; receptor-type tyrosine-protein phosphatase C [EC:3.1.3.48]
K07887 RAB5A; Ras-related protein Rab-5A
K07888 RAB5B; Ras-related protein Rab-5B
K07889 RAB5C; Ras-related protein Rab-5C
K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
K07897 RAB7A; Ras-related protein Rab-7A
K07898 RAB7B; Ras-related protein Rab-7B
K23282 PLEKHM1; pleckstrin homology domain-containing family M member 1
K20179 VPS11; vacuolar protein sorting-associated protein 11
K20180 VPS16; vacuolar protein sorting-associated protein 16
K20181 VPS18; vacuolar protein sorting-associated protein 18
K20182 VPS33A; vacuolar protein sorting-associated protein 33A
K20183 VPS39; Vam6/Vps39-like protein vacuolar protein sorting-associated protein 39
K20184 VPS41; vacuolar protein sorting-associated protein 41
K13883 RILP; Rab-interacting lysosomal protein
K10413 DYNC1H; dynein heavy chain 1, cytosolic
K10414 DYNC2H; dynein heavy chain 2, cytosolic
K10415 DYNC1I; dynein intermediate chain, cytosolic
K10415 DYNC1I; dynein intermediate chain, cytosolic
K10416 DYNC1LI; dynein light intermediate chain 1, cytosolic
K10416 DYNC1LI; dynein light intermediate chain 1, cytosolic
K10417 DYNC2LI; dynein light intermediate chain 2, cytosolic
K10418 DYNLL; dynein light chain LC8-type
K10418 DYNLL; dynein light chain LC8-type
K10419 DYNLRB; dynein light chain roadblock-type
K10419 DYNLRB; dynein light chain roadblock-type
K10420 DYNLT; dynein light chain Tctex-type 1
K10420 DYNLT; dynein light chain Tctex-type 1
K04648 DCTN1; dynactin 1
K10424 DCTN2; dynactin 2
K10425 DCTN3; dynactin 3
K10426 DCTN4; dynactin 4
K10427 DCTN5; dynactin 5
K10428 DCTN6; dynactin 6
K16575 ACTR1; centractin
K16575 ACTR1; centractin
K16576 ACTR10; actin-related protein 10
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07374 TUBA; tubulin alpha
K07375 TUBB; tubulin beta
K07375 TUBB; tubulin beta
K07375 TUBB; tubulin beta
K07375 TUBB; tubulin beta
K07375 TUBB; tubulin beta
K07375 TUBB; tubulin beta
K07375 TUBB; tubulin beta
K07375 TUBB; tubulin beta
K07375 TUBB; tubulin beta
K21954 FYCO1; FYVE and coiled-coil domain-containing protein 1
K07955 ARL8; ADP-ribosylation factor-like protein 8
K07955 ARL8; ADP-ribosylation factor-like protein 8
K15348 PLEKHM2; pleckstrin homology domain-containing family M member 2
K10396 KIF5; kinesin family member 5
K10396 KIF5; kinesin family member 5
K10396 KIF5; kinesin family member 5
K10407 KLC; kinesin light chain
K10407 KLC; kinesin light chain
K10407 KLC; kinesin light chain
K10407 KLC; kinesin light chain
K23935 ACBD3; golgi resident protein GCP60
K04513 RHOA; Ras homolog gene family, member A
K10089 M6PR; cation-dependent mannose-6-phosphate receptor
K07899 RAB9A; Ras-related protein Rab-9A
K07900 RAB9B; Ras-related protein Rab-9B
K20282 GCC2; GRIP and coiled-coil domain-containing protein 2
K23937 STX10; syntaxin 10
K05759 PFN; profilin
K05759 PFN; profilin
K05759 PFN; profilin
K05759 PFN; profilin
K04437 FLNA; filamin
K04437 FLNA; filamin
K04437 FLNA; filamin
K07195 EXOC7; exocyst complex component 7
K19984 EXOC5; exocyst complex component 5
K06111 EXOC4; exocyst complex component 4
K17637 EXOC2; exocyst complex component 2
K07834 RALA; Ras-related protein Ral-A
K05692 ACTB_G1; actin beta/gamma 1
K05692 ACTB_G1; actin beta/gamma 1
K17274 S100A10; protein S100-A10
K17092 ANXA2; annexin A2
K23934 AHNAK; neuroblast differentiation-associated protein AHNAK
K23934 AHNAK; neuroblast differentiation-associated protein AHNAK
K07864 RHOJ; Ras homolog gene family, member J
K13744 ARHGEF26; Rho guanine nucleotide exchange factor 26
K07863 RHOG; Ras homolog gene family, member G
K12366 ELMO1; engulfment and cell motility protein 1
K18985 ELMO2; engulfment and cell motility protein 2
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K10351 MYL2; myosin regulatory light chain 2
K12753 MYL5; myosin regulatory light chain 5
K12754 MYL7; myosin regulatory light chain 7
K12755 MYL9; myosin regulatory light chain 9
K12756 MYL10; myosin regulatory light chain 10
K12757 MYL12; myosin regulatory light chain 12
K12757 MYL12; myosin regulatory light chain 12
K12758 MYLPF; fast skeletal myosin light chain 2
K23938 FHOD1; FH1/FH2 domain-containing protein 1
K04393 CDC42; cell division control protein 42
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K05750 NCKAP1; NCK-associated protein 1
K05750 NCKAP1; NCK-associated protein 1
K05749 CYFIP; cytoplasmic FMR1 interacting protein
K05749 CYFIP; cytoplasmic FMR1 interacting protein
K23649 ABI1; abl interactor 1
K05752 C3ORF10; chromosome 3 open reading frame 10
K06083 WASF3; WAS protein family, member 3
K17260 ACTR2; actin-related protein 2
K18584 ACTR3; actin-related protein 3
K18584 ACTR3; actin-related protein 3
K18584 ACTR3; actin-related protein 3
K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
K05758 ARPC2; actin related protein 2/3 complex, subunit 2
K05756 ARPC3; actin related protein 2/3 complex, subunit 3
K05755 ARPC4; actin related protein 2/3 complex, subunit 4
K05754 ARPC5; actin related protein 2/3 complex, subunit 5
K05754 ARPC5; actin related protein 2/3 complex, subunit 5
K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
K05733 PAK3; p21-activated kinase 3 [EC:2.7.11.1]
K10358 MYO6; myosin VI
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K21289 PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153]
K00923 PIK3C2; phosphatidylinositol-4-phosphate 3-kinase [EC:2.7.1.154]
K00923 PIK3C2; phosphatidylinositol-4-phosphate 3-kinase [EC:2.7.1.154]
K00923 PIK3C2; phosphatidylinositol-4-phosphate 3-kinase [EC:2.7.1.154]
K18441 CYTH; cytohesin
K18441 CYTH; cytohesin
K18441 CYTH; cytohesin
K18441 CYTH; cytohesin
K07941 ARF6; ADP-ribosylation factor 6
K07937 ARF1_2; ADP-ribosylation factor 1/2
K17923 SNX9_18_33; sorting nexin-9/18/33
K17923 SNX9_18_33; sorting nexin-9/18/33
K17923 SNX9_18_33; sorting nexin-9/18/33
K23612 WASL; neural Wiskott-Aldrich syndrome protein
K23484 DNM2; dynamin 2 [EC:3.6.5.5]
K10169 TLR6; toll-like receptor 6
K10159 TLR2; toll-like receptor 2
K05403 TIRAP; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04391 CD14; monocyte differentiation antigen CD14
K10160 TLR4; toll-like receptor 4
K05400 LY96; lymphocyte antigen 96
K10168 TLR5; toll-like receptor 5
K10161 TLR9; toll-like receptor 9
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04403 MAP3K7IP1; TAK1-binding protein 1
K04404 MAP3K7IP2; TAK1-binding protein 2
K12793 MAP3K7IP3; TAK1-binding protein 3
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K08727 NOD1; nucleotide-binding oligomerization domain-containing protein 1
K04079 HSP90A; molecular chaperone HtpG
K04079 HSP90A; molecular chaperone HtpG
K09487 HSP90B; heat shock protein 90kDa beta
K08846 RIPK2; receptor-interacting serine/threonine-protein kinase 2 [EC:2.7.11.1]
K18423 CSE1; exportin-2 (importin alpha re-exporter)
K23940 KPNA1; importin subunit alpha-5
K23583 KPNA3_4; importin subunit alpha-4/3
K23583 KPNA3_4; importin subunit alpha-4/3
K02985 RP-S3e; small subunit ribosomal protein S3e
K02833 HRAS; GTPase HRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04432 MAP2K3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04430 MAP2K4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K03156 TNF; tumor necrosis factor superfamily, member 2
K04519 IL1B; interleukin 1 beta
K05405 IL6; interleukin 6
K10030 IL8; interleukin 8
K02105 CTNNB1; catenin beta 1
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K04377 MYC; Myc proto-oncogene protein
K06071 PKN1; serine/threonine-protein kinase N1 [EC:2.7.11.13]
K10302 FBXO22; F-box protein 22
K03094 SKP1; S-phase kinase-associated protein 1
K03158 TNFRSF1A; tumor necrosis factor receptor superfamily member 1A
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K02861 RIPK1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12]
K04721 TNFSF10; tumor necrosis factor ligand superfamily member 10
K04722 TNFRSF10A_B; tumor necrosis factor receptor superfamily member 10A/B
K04722 TNFRSF10A_B; tumor necrosis factor receptor superfamily member 10A/B
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K08847 RIPK3; receptor-interacting serine/threonine-protein kinase 3 [EC:2.7.11.1]
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K08738 CYC; cytochrome c
K02161 BCL2; apoptosis regulator Bcl-2
K02187 CASP3; caspase 3 [EC:3.4.22.56]
K04397 CASP7; caspase 7 [EC:3.4.22.60]
K07856 RHOB; Ras homolog gene family, member B
K07873 RHOH; Ras homolog gene family, member H
K07829 RRAS; Ras-related protein R-Ras
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K08849 MLKL; mixed lineage kinase domain-like [EC:2.7.11.1]
K03671 trxA; thioredoxin 1
K03671 trxA; thioredoxin 1
K12800 NLRP3; NACHT, LRR and PYD domains-containing protein 3
K12807 NAIP; baculoviral IAP repeat-containing protein 1
K12805 NLRC4; NLR family CARD domain-containing protein 4
K12799 PYCARD; apoptosis-associated speck-like protein containing a CARD
K01370 CASP1; caspase 1 [EC:3.4.22.36]
K05482 IL18; interleukin 18
K04394 CASP4; caspase 4 [EC:3.4.22.57 3.4.22.64]
K04395 CASP5; caspase 5 [EC:3.4.22.58]
K20917 GSDMD; gasdermin-D
     05131 Shigellosis [PATH:hsa05131]
       960 CD44; CD44 molecule (Indian blood group)
       3678 ITGA5; integrin subunit alpha 5
       3688 ITGB1; integrin subunit beta 1
       6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase
       5747 PTK2; protein tyrosine kinase 2
       1398 CRK; CRK proto-oncogene, adaptor protein
       1399 CRKL; CRK like proto-oncogene, adaptor protein
       9564 BCAR1; BCAR1 scaffold protein, Cas family member
       2017 CTTN; cortactin
       3059 HCLS1; hematopoietic cell-specific Lyn substrate 1
       5829 PXN; paxillin
       9844 ELMO1; engulfment and cell motility 1
       63916 ELMO2; engulfment and cell motility 2
       1793 DOCK1; dedicator of cytokinesis 1
       5879 RAC1; Rac family small GTPase 1
       8936 WASF1; WASP family member 1
       10163 WASF2; WASP family member 2
       10097 ACTR2; actin related protein 2
       57180 ACTR3B; actin related protein 3B
       653857 ACTR3C; actin related protein 3C
       10096 ACTR3; actin related protein 3
       10095 ARPC1B; actin related protein 2/3 complex subunit 1B
       10552 ARPC1A; actin related protein 2/3 complex subunit 1A
       10109 ARPC2; actin related protein 2/3 complex subunit 2
       10094 ARPC3; actin related protein 2/3 complex subunit 3
       10093 ARPC4; actin related protein 2/3 complex subunit 4
       10092 ARPC5; actin related protein 2/3 complex subunit 5
       81873 ARPC5L; actin related protein 2/3 complex subunit 5 like
       71 ACTG1; actin gamma 1
       60 ACTB; actin beta
       387 RHOA; ras homolog family member A
       1729 DIAPH1; diaphanous related formin 1
       6093 ROCK1; Rho associated coiled-coil containing protein kinase 1
       9475 ROCK2; Rho associated coiled-coil containing protein kinase 2
       4633 MYL2; myosin light chain 2
       4636 MYL5; myosin light chain 5
       58498 MYL7; myosin light chain 7
       10398 MYL9; myosin light chain 9
       93408 MYL10; myosin light chain 10
       103910 MYL12B; myosin light chain 12B
       10627 MYL12A; myosin light chain 12A
       29895 MYLPF; myosin light chain, phosphorylatable, fast skeletal muscle
       87 ACTN1; actinin alpha 1
       81 ACTN4; actinin alpha 4
       3611 ILK; integrin linked kinase
       7094 TLN1; talin 1
       83660 TLN2; talin 2
       7414 VCL; vinculin
       998 CDC42; cell division cycle 42
       8976 WASL; WASP like actin nucleation promoting factor
       345456 PFN3; profilin 3
       5216 PFN1; profilin 1
       5217 PFN2; profilin 2
       375189 PFN4; profilin family member 4
       1956 EGFR; epidermal growth factor receptor
       5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
       5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
       8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
       9265 CYTH3; cytohesin 3
       27128 CYTH4; cytohesin 4
       9266 CYTH2; cytohesin 2
       9267 CYTH1; cytohesin 1
       382 ARF6; ADP ribosylation factor 6
       375 ARF1; ADP ribosylation factor 1
       207 AKT1; AKT serine/threonine kinase 1
       208 AKT2; AKT serine/threonine kinase 2
       10000 AKT3; AKT serine/threonine kinase 3
       2308 FOXO1; forkhead box O1
       2309 FOXO3; forkhead box O3
       4303 FOXO4; forkhead box O4
       100132074 FOXO6; forkhead box O6
       2931 GSK3A; glycogen synthase kinase 3 alpha
       2932 GSK3B; glycogen synthase kinase 3 beta
       6198 RPS6KB1; ribosomal protein S6 kinase B1
       6199 RPS6KB2; ribosomal protein S6 kinase B2
       4193 MDM2; MDM2 proto-oncogene
       23236 PLCB1; phospholipase C beta 1
       5330 PLCB2; phospholipase C beta 2
       5331 PLCB3; phospholipase C beta 3
       5332 PLCB4; phospholipase C beta 4
       5333 PLCD1; phospholipase C delta 1
       113026 PLCD3; phospholipase C delta 3
       84812 PLCD4; phospholipase C delta 4
       51196 PLCE1; phospholipase C epsilon 1
       5335 PLCG1; phospholipase C gamma 1
       5336 PLCG2; phospholipase C gamma 2
       89869 PLCZ1; phospholipase C zeta 1
       3708 ITPR1; inositol 1,4,5-trisphosphate receptor type 1
       3709 ITPR2; inositol 1,4,5-trisphosphate receptor type 2
       3710 ITPR3; inositol 1,4,5-trisphosphate receptor type 3
       831 CAST; calpastatin
       823 CAPN1; calpain 1
       824 CAPN2; calpain 2
       826 CAPNS1; calpain small subunit 1
       472 ATM; ATM serine/threonine kinase
       7157 TP53; tumor protein p53
       598 BCL2L1; BCL2 like 1
       596 BCL2; BCL2 apoptosis regulator
       3101 HK3; hexokinase 3
       3098 HK1; hexokinase 1
       3099 HK2; hexokinase 2
       80201 HKDC1; hexokinase domain containing 1
       7416 VDAC1; voltage dependent anion channel 1
       581 BAX; BCL2 associated X, apoptosis regulator
       54205 CYCS; cytochrome c, somatic
       664 BNIP3; BCL2 interacting protein 3
       5481 PPID; peptidylprolyl isomerase D
       837 CASP4; caspase 4
       3553 IL1B; interleukin 1 beta
       3606 IL18; interleukin 18
       7124 TNF; tumor necrosis factor
       7132 TNFRSF1A; TNF receptor superfamily member 1A
       8717 TRADD; TNFRSF1A associated via death domain
       7186 TRAF2; TNF receptor associated factor 2
       7188 TRAF5; TNF receptor associated factor 5
       8737 RIPK1; receptor interacting serine/threonine kinase 1
       6885 MAP3K7; mitogen-activated protein kinase kinase kinase 7
       10454 TAB1; TGF-beta activated kinase 1 (MAP3K7) binding protein 1
       23118 TAB2; TGF-beta activated kinase 1 (MAP3K7) binding protein 2
       257397 TAB3; TGF-beta activated kinase 1 (MAP3K7) binding protein 3
       8517 IKBKG; inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
       1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
       3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
       4792 NFKBIA; NFKB inhibitor alpha
       4793 NFKBIB; NFKB inhibitor beta
       4790 NFKB1; nuclear factor kappa B subunit 1
       5970 RELA; RELA proto-oncogene, NF-kB subunit
       3576 CXCL8; C-X-C motif chemokine ligand 8
       92610 TIFA; TRAF interacting protein with forkhead associated domain
       3554 IL1R1; interleukin 1 receptor type 1
       929 CD14; CD14 molecule
       7099 TLR4; toll like receptor 4
       7100 TLR5; toll like receptor 5
       7189 TRAF6; TNF receptor associated factor 6
       5580 PRKCD; protein kinase C delta
       5581 PRKCE; protein kinase C epsilon
       5588 PRKCQ; protein kinase C theta
       10892 MALT1; MALT1 paracaspase
       8915 BCL10; BCL10 immune signaling adaptor
       10392 NOD1; nucleotide binding oligomerization domain containing 1
       9181 ARHGEF2; Rho/Rac guanine nucleotide exchange factor 2
       8767 RIPK2; receptor interacting serine/threonine kinase 2
       5599 MAPK8; mitogen-activated protein kinase 8
       5602 MAPK10; mitogen-activated protein kinase 10
       5601 MAPK9; mitogen-activated protein kinase 9
       3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
       7335 UBE2V1; ubiquitin conjugating enzyme E2 V1
       7336 UBE2V2; ubiquitin conjugating enzyme E2 V2
       389898 UBE2NL; ubiquitin conjugating enzyme E2 N like (gene/pseudogene)
       7334 UBE2N; ubiquitin conjugating enzyme E2 N
       10616 RBCK1; RANBP2-type and C3HC4-type zinc finger containing 1
       55072 RNF31; ring finger protein 31
       81858 SHARPIN; SHANK associated RH domain interactor
       10318 TNIP1; TNFAIP3 interacting protein 1
       51619 UBE2D4; ubiquitin conjugating enzyme E2 D4 (putative)
       7321 UBE2D1; ubiquitin conjugating enzyme E2 D1
       7322 UBE2D2; ubiquitin conjugating enzyme E2 D2
       7323 UBE2D3; ubiquitin conjugating enzyme E2 D3
       9978 RBX1; ring-box 1
       8454 CUL1; cullin 1
       6500 SKP1; S-phase kinase associated protein 1
       8945 BTRC; beta-transducin repeat containing E3 ubiquitin protein ligase
       23291 FBXW11; F-box and WD repeat domain containing 11
       115004 CGAS; cyclic GMP-AMP synthase
       340061 STING1; stimulator of interferon response cGAMP interactor 1
       4615 MYD88; MYD88 innate immune signal transduction adaptor
       29110 TBK1; TANK binding kinase 1
       3661 IRF3; interferon regulatory factor 3
       3456 IFNB1; interferon beta 1
       7307 U2AF1; U2 small nuclear RNA auxiliary factor 1
       102724594 U2AF1L5; U2 small nuclear RNA auxiliary factor 1 like 5
       199746 U2AF1L4; U2 small nuclear RNA auxiliary factor 1 like 4
       6352 CCL5; C-C motif chemokine ligand 5
       1437 CSF2; colony stimulating factor 2
       5594 MAPK1; mitogen-activated protein kinase 1
       5595 MAPK3; mitogen-activated protein kinase 3
       5600 MAPK11; mitogen-activated protein kinase 11
       6300 MAPK12; mitogen-activated protein kinase 12
       5603 MAPK13; mitogen-activated protein kinase 13
       1432 MAPK14; mitogen-activated protein kinase 14
       9252 RPS6KA5; ribosomal protein S6 kinase A5
       440093 H3-5; H3.5 histone
       3021 H3-3B; H3.3 histone B
       8351 H3C4; H3 clustered histone 4
       8352 H3C3; H3 clustered histone 3
       8350 H3C1; H3 clustered histone 1
       3020 H3-3A; H3.3 histone A
       8290 H3-4; H3.4 histone
       126961 H3C14; H3 clustered histone 14
       333932 H3C15; H3 clustered histone 15
       653604 H3C13; H3 clustered histone 13
       8353 H3C6; H3 clustered histone 6
       8354 H3C11; H3 clustered histone 11
       8355 H3C8; H3 clustered histone 8
       8356 H3C12; H3 clustered histone 12
       8357 H3C10; H3 clustered histone 10
       8358 H3C2; H3 clustered histone 2
       8968 H3C7; H3 clustered histone 7
       11335 CBX3; chromobox 3
       8678 BECN1; beclin 1
       441925 BECN2; beclin 2
       22863 ATG14; autophagy related 14
       30849 PIK3R4; phosphoinositide-3-kinase regulatory subunit 4
       5289 PIK3C3; phosphatidylinositol 3-kinase catalytic subunit type 3
       10670 RRAGA; Ras related GTP binding A
       10325 RRAGB; Ras related GTP binding B
       64121 RRAGC; Ras related GTP binding C
       58528 RRAGD; Ras related GTP binding D
       2475 MTOR; mechanistic target of rapamycin kinase
       57521 RPTOR; regulatory associated protein of MTOR complex 1
       84335 AKT1S1; AKT1 substrate 1
       55054 ATG16L1; autophagy related 16 like 1
       9474 ATG5; autophagy related 5
       9140 ATG12; autophagy related 12
       11337 GABARAP; GABA type A receptor-associated protein
       23710 GABARAPL1; GABA type A receptor associated protein like 1
       11345 GABARAPL2; GABA type A receptor associated protein like 2
       718 C3; complement C3
       8878 SQSTM1; sequestosome 1
       10241 CALCOCO2; calcium binding and coiled-coil domain 2
       7311 UBA52; ubiquitin A-52 residue ribosomal protein fusion product 1
       6233 RPS27A; ribosomal protein S27a
       7314 UBB; ubiquitin B
       7316 UBC; ubiquitin C
       4735 SEPTIN2; septin 2
       10801 SEPTIN9; septin 9
       124404 SEPTIN12; septin 12
       55964 SEPTIN3; septin 3
       23157 SEPTIN6; septin 6
       55752 SEPTIN11; septin 11
       23176 SEPTIN8; septin 8
       989 SEPTIN7; septin 7
       26100 WIPI2; WD repeat domain, phosphoinositide interacting 2
       55062 WIPI1; WD repeat domain, phosphoinositide interacting 1
       25851 TECPR1; tectonin beta-propeller repeat containing 1
       23048 FNBP1; formin binding protein 1
       54874 FNBP1L; formin binding protein 1 like
       11146 GLMN; glomulin, FKBP associated protein
       114548 NLRP3; NLR family pyrin domain containing 3
       4671 NAIP; NLR family apoptosis inhibitory protein
       58484 NLRC4; NLR family CARD domain containing 4
       29108 PYCARD; PYD and CARD domain containing
       834 CASP1; caspase 1
K06256 CD44; CD44 antigen
K06484 ITGA5; integrin alpha 5
K05719 ITGB1; integrin beta 1
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K05726 BCAR1; breast cancer anti-estrogen resistance 1
K06106 CTTN; cortactin
K06106 CTTN; cortactin
K05760 PXN; paxillin
K12366 ELMO1; engulfment and cell motility protein 1
K18985 ELMO2; engulfment and cell motility protein 2
K13708 DOCK1; dedicator of cytokinesis protein 1
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K05753 WASF1; WAS protein family, member 1
K05748 WASF2; WAS protein family, member 2
K17260 ACTR2; actin-related protein 2
K18584 ACTR3; actin-related protein 3
K18584 ACTR3; actin-related protein 3
K18584 ACTR3; actin-related protein 3
K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
K05758 ARPC2; actin related protein 2/3 complex, subunit 2
K05756 ARPC3; actin related protein 2/3 complex, subunit 3
K05755 ARPC4; actin related protein 2/3 complex, subunit 4
K05754 ARPC5; actin related protein 2/3 complex, subunit 5
K05754 ARPC5; actin related protein 2/3 complex, subunit 5
K05692 ACTB_G1; actin beta/gamma 1
K05692 ACTB_G1; actin beta/gamma 1
K04513 RHOA; Ras homolog gene family, member A
K05740 DIAPH1; diaphanous 1
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K10351 MYL2; myosin regulatory light chain 2
K12753 MYL5; myosin regulatory light chain 5
K12754 MYL7; myosin regulatory light chain 7
K12755 MYL9; myosin regulatory light chain 9
K12756 MYL10; myosin regulatory light chain 10
K12757 MYL12; myosin regulatory light chain 12
K12757 MYL12; myosin regulatory light chain 12
K12758 MYLPF; fast skeletal myosin light chain 2
K05699 ACTN1_4; actinin alpha 1/4
K05699 ACTN1_4; actinin alpha 1/4
K06272 ILK; integrin-linked kinase [EC:2.7.11.1]
K06271 TLN; talin
K06271 TLN; talin
K05700 VCL; vinculin
K04393 CDC42; cell division control protein 42
K23612 WASL; neural Wiskott-Aldrich syndrome protein
K05759 PFN; profilin
K05759 PFN; profilin
K05759 PFN; profilin
K05759 PFN; profilin
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K18441 CYTH; cytohesin
K18441 CYTH; cytohesin
K18441 CYTH; cytohesin
K18441 CYTH; cytohesin
K07941 ARF6; ADP-ribosylation factor 6
K07937 ARF1_2; ADP-ribosylation factor 1/2
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K07201 FOXO1; forkhead box protein O1
K09408 FOXO3; forkhead box protein O3
K12358 FOXO4; forkhead box protein O4
K17847 FOXO6; forkhead box protein O6
K08822 GSK3A; glycogen synthase kinase 3 alpha [EC:2.7.11.26]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
K05860 PLCE; phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05859 PLCG2; phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K05861 PLCZ; phosphatidylinositol phospholipase C, zeta [EC:3.1.4.11]
K04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1
K04959 ITPR2; inositol 1,4,5-triphosphate receptor type 2
K04960 ITPR3; inositol 1,4,5-triphosphate receptor type 3
K04281 CAST; calpastatin
K01367 CAPN1; calpain-1 [EC:3.4.22.52]
K03853 CAPN2; calpain-2 [EC:3.4.22.53]
K08583 CAPNS1; calpain, small subunit 1
K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
K04451 TP53; tumor protein p53
K04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)
K02161 BCL2; apoptosis regulator Bcl-2
K00844 HK; hexokinase [EC:2.7.1.1]
K00844 HK; hexokinase [EC:2.7.1.1]
K00844 HK; hexokinase [EC:2.7.1.1]
K00844 HK; hexokinase [EC:2.7.1.1]
K05862 VDAC1; voltage-dependent anion channel protein 1
K02159 BAX; apoptosis regulator BAX
K08738 CYC; cytochrome c
K15464 BNIP3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
K05864 PPID; peptidyl-prolyl isomerase D [EC:5.2.1.8]
K04394 CASP4; caspase 4 [EC:3.4.22.57 3.4.22.64]
K04519 IL1B; interleukin 1 beta
K05482 IL18; interleukin 18
K03156 TNF; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A; tumor necrosis factor receptor superfamily member 1A
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K09849 TRAF5; TNF receptor-associated factor 5
K02861 RIPK1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K04403 MAP3K7IP1; TAK1-binding protein 1
K04404 MAP3K7IP2; TAK1-binding protein 2
K12793 MAP3K7IP3; TAK1-binding protein 3
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02581 NFKBIB; NF-kappa-B inhibitor beta
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K10030 IL8; interleukin 8
K23826 TIFA; TRAF-interacting protein with FHA domain-containing protein A
K04386 IL1R1; interleukin 1 receptor type I
K04391 CD14; monocyte differentiation antigen CD14
K10160 TLR4; toll-like receptor 4
K10168 TLR5; toll-like receptor 5
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
K18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
K18052 PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]
K07369 MALT1; mucosa-associated lymphoid tissue lymphoma translocation protein 1 [EC:3.4.22.-]
K07368 BCL10; B-cell CLL/lymphoma 10
K08727 NOD1; nucleotide-binding oligomerization domain-containing protein 1
K12791 ARHGEF2; Rho guanine nucleotide exchange factor 2
K08846 RIPK2; receptor-interacting serine/threonine-protein kinase 2 [EC:2.7.11.1]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04448 JUN; transcription factor AP-1
K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
K10630 RBCK1; RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.31]
K11974 RNF31; E3 ubiquitin-protein ligase RNF31 [EC:2.3.2.31]
K20894 SHARPIN; shank-associated RH domain-interacting protein
K23829 TNIP1; TNFAIP3-interacting protein 1
K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
K03868 RBX1; RING-box protein 1 [EC:2.3.2.32]
K03347 CUL1; cullin 1
K03094 SKP1; S-phase kinase-associated protein 1
K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
K17834 MB21D1; cyclic GMP-AMP synthase [EC:2.7.7.86]
K12654 TMEM173; transmembrane protein 173
K04729 MYD88; myeloid differentiation primary response protein MyD88
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K05411 IRF3; interferon regulatory factor 3
K05415 IFNB; interferon beta
K12836 U2AF1; splicing factor U2AF 35 kDa subunit
K12836 U2AF1; splicing factor U2AF 35 kDa subunit
K12836 U2AF1; splicing factor U2AF 35 kDa subunit
K12499 CCL5; C-C motif chemokine 5
K05427 CSF2; granulocyte-macrophage colony-stimulating factor
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04445 RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
K11253 H3; histone H3
K11253 H3; histone H3
K11253 H3; histone H3
K11253 H3; histone H3
K11253 H3; histone H3
K11253 H3; histone H3
K11253 H3; histone H3
K11253 H3; histone H3
K11253 H3; histone H3
K11253 H3; histone H3
K11253 H3; histone H3
K11253 H3; histone H3
K11253 H3; histone H3
K11253 H3; histone H3
K11253 H3; histone H3
K11253 H3; histone H3
K11253 H3; histone H3
K11586 CBX3; chromobox protein 3
K08334 BECN; beclin
K08334 BECN; beclin
K17889 ATG14L; beclin 1-associated autophagy-related key regulator
K08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
K16185 RRAGA_B; Ras-related GTP-binding protein A/B
K16185 RRAGA_B; Ras-related GTP-binding protein A/B
K16186 RRAGC_D; Ras-related GTP-binding protein C/D
K16186 RRAGC_D; Ras-related GTP-binding protein C/D
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K07204 RAPTOR; regulatory associated protein of mTOR
K16184 AKT1S1; proline-rich AKT1 substrate 1
K17890 ATG16L1; autophagy-related protein 16-1
K08339 ATG5; autophagy-related protein 5
K08336 ATG12; ubiquitin-like protein ATG12
K08341 GABARAP; GABA(A) receptor-associated protein
K08341 GABARAP; GABA(A) receptor-associated protein
K08341 GABARAP; GABA(A) receptor-associated protein
K03990 C3; complement component 3
K14381 SQSTM1; sequestosome 1
K21348 CALCOCO2; calcium-binding and coiled-coil domain-containing protein 2
K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
K04551 UBB; ubiquitin B
K08770 UBC; ubiquitin C
K16942 SEPT2; septin 2
K16938 SEPT3_9_12; septin 3/9/12
K16938 SEPT3_9_12; septin 3/9/12
K16938 SEPT3_9_12; septin 3/9/12
K16939 SEPT6_8_11; septin 6/8/11
K16939 SEPT6_8_11; septin 6/8/11
K16939 SEPT6_8_11; septin 6/8/11
K16944 SEPT7; septin 7
K17908 WIPI1_2; autophagy-related protein 18
K17908 WIPI1_2; autophagy-related protein 18
K17988 TECPR1; tectonin beta-propeller repeat-containing protein 1
K20121 FNBP1; formin-binding protein 1
K20121 FNBP1; formin-binding protein 1
K23345 GLMN; glomulin
K12800 NLRP3; NACHT, LRR and PYD domains-containing protein 3
K12807 NAIP; baculoviral IAP repeat-containing protein 1
K12805 NLRC4; NLR family CARD domain-containing protein 4
K12799 PYCARD; apoptosis-associated speck-like protein containing a CARD
K01370 CASP1; caspase 1 [EC:3.4.22.36]
     05135 Yersinia infection [PATH:hsa05135]
       2335 FN1; fibronectin 1
       3676 ITGA4; integrin subunit alpha 4
       3678 ITGA5; integrin subunit alpha 5
       3688 ITGB1; integrin subunit beta 1
       391 RHOG; ras homolog family member G
       6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase
       5747 PTK2; protein tyrosine kinase 2
       2185 PTK2B; protein tyrosine kinase 2 beta
       1398 CRK; CRK proto-oncogene, adaptor protein
       1399 CRKL; CRK like proto-oncogene, adaptor protein
       9564 BCAR1; BCAR1 scaffold protein, Cas family member
       9844 ELMO1; engulfment and cell motility 1
       63916 ELMO2; engulfment and cell motility 2
       1793 DOCK1; dedicator of cytokinesis 1
       102723407 IGH; immunoglobulin heavy variable 4-38-2-like
       2212 FCGR2A; Fc fragment of IgG receptor IIa
       5879 RAC1; Rac family small GTPase 1
       5880 RAC2; Rac family small GTPase 2
       5881 RAC3; Rac family small GTPase 3
       23396 PIP5K1C; phosphatidylinositol-4-phosphate 5-kinase type 1 gamma
       8394 PIP5K1A; phosphatidylinositol-4-phosphate 5-kinase type 1 alpha
       8395 PIP5K1B; phosphatidylinositol-4-phosphate 5-kinase type 1 beta
       382 ARF6; ADP ribosylation factor 6
       8976 WASL; WASP like actin nucleation promoting factor
       10097 ACTR2; actin related protein 2
       57180 ACTR3B; actin related protein 3B
       653857 ACTR3C; actin related protein 3C
       10096 ACTR3; actin related protein 3
       10095 ARPC1B; actin related protein 2/3 complex subunit 1B
       10552 ARPC1A; actin related protein 2/3 complex subunit 1A
       10109 ARPC2; actin related protein 2/3 complex subunit 2
       10094 ARPC3; actin related protein 2/3 complex subunit 3
       10093 ARPC4; actin related protein 2/3 complex subunit 4
       10092 ARPC5; actin related protein 2/3 complex subunit 5
       81873 ARPC5L; actin related protein 2/3 complex subunit 5 like
       71 ACTG1; actin gamma 1
       60 ACTB; actin beta
       147179 WIPF2; WAS/WASL interacting protein family member 2
       7456 WIPF1; WAS/WASL interacting protein family member 1
       644150 WIPF3; WAS/WASL interacting protein family member 3
       10458 BAIAP2; BAR/IMD domain containing adaptor protein 2
       10163 WASF2; WASP family member 2
       5829 PXN; paxillin
       9815 GIT2; GIT ArfGAP 2
       8874 ARHGEF7; Rho guanine nucleotide exchange factor 7
       998 CDC42; cell division cycle 42
       7454 WAS; WASP actin nucleation promoting factor
       2776 GNAQ; G protein subunit alpha q
       23365 ARHGEF12; Rho guanine nucleotide exchange factor 12
       9138 ARHGEF1; Rho guanine nucleotide exchange factor 1
       64283 ARHGEF28; Rho guanine nucleotide exchange factor 28
       387 RHOA; ras homolog family member A
       6093 ROCK1; Rho associated coiled-coil containing protein kinase 1
       9475 ROCK2; Rho associated coiled-coil containing protein kinase 2
       2533 FYB1; FYN binding protein 1
       8935 SKAP2; src kinase associated phosphoprotein 2
       114548 NLRP3; NLR family pyrin domain containing 3
       58484 NLRC4; NLR family CARD domain containing 4
       5585 PKN1; protein kinase N1
       5586 PKN2; protein kinase N2
       6197 RPS6KA3; ribosomal protein S6 kinase A3
       6195 RPS6KA1; ribosomal protein S6 kinase A1
       6196 RPS6KA2; ribosomal protein S6 kinase A2
       27330 RPS6KA6; ribosomal protein S6 kinase A6
       4210 MEFV; MEFV innate immuity regulator, pyrin
       3984 LIMK1; LIM domain kinase 1
       29108 PYCARD; PYD and CARD domain containing
       834 CASP1; caspase 1
       3606 IL18; interleukin 18
       3553 IL1B; interleukin 1 beta
       7099 TLR4; toll like receptor 4
       4615 MYD88; MYD88 innate immune signal transduction adaptor
       51135 IRAK4; interleukin 1 receptor associated kinase 4
       3654 IRAK1; interleukin 1 receptor associated kinase 1
       7189 TRAF6; TNF receptor associated factor 6
       7186 TRAF2; TNF receptor associated factor 2
       10454 TAB1; TGF-beta activated kinase 1 (MAP3K7) binding protein 1
       23118 TAB2; TGF-beta activated kinase 1 (MAP3K7) binding protein 2
       6885 MAP3K7; mitogen-activated protein kinase kinase kinase 7
       8517 IKBKG; inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
       1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
       3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
       4792 NFKBIA; NFKB inhibitor alpha
       4790 NFKB1; nuclear factor kappa B subunit 1
       5970 RELA; RELA proto-oncogene, NF-kB subunit
       5604 MAP2K1; mitogen-activated protein kinase kinase 1
       5605 MAP2K2; mitogen-activated protein kinase kinase 2
       5594 MAPK1; mitogen-activated protein kinase 1
       5595 MAPK3; mitogen-activated protein kinase 3
       5606 MAP2K3; mitogen-activated protein kinase kinase 3
       5608 MAP2K6; mitogen-activated protein kinase kinase 6
       5600 MAPK11; mitogen-activated protein kinase 11
       6300 MAPK12; mitogen-activated protein kinase 12
       5603 MAPK13; mitogen-activated protein kinase 13
       1432 MAPK14; mitogen-activated protein kinase 14
       6416 MAP2K4; mitogen-activated protein kinase kinase 4
       5609 MAP2K7; mitogen-activated protein kinase kinase 7
       5599 MAPK8; mitogen-activated protein kinase 8
       5602 MAPK10; mitogen-activated protein kinase 10
       5601 MAPK9; mitogen-activated protein kinase 9
       2353 FOS; Fos proto-oncogene, AP-1 transcription factor subunit
       3725 JUN; Jun proto-oncogene, AP-1 transcription factor subunit
       148022 TICAM1; toll like receptor adaptor molecule 1
       29110 TBK1; TANK binding kinase 1
       3661 IRF3; interferon regulatory factor 3
       7124 TNF; tumor necrosis factor
       3569 IL6; interleukin 6
       3576 CXCL8; C-X-C motif chemokine ligand 8
       3456 IFNB1; interferon beta 1
       5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
       5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
       8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
       207 AKT1; AKT serine/threonine kinase 1
       208 AKT2; AKT serine/threonine kinase 2
       10000 AKT3; AKT serine/threonine kinase 3
       2932 GSK3B; glycogen synthase kinase 3 beta
       6347 CCL2; C-C motif chemokine ligand 2
       920 CD4; CD4 molecule
       925 CD8A; CD8a molecule
       926 CD8B; CD8b molecule
       927 CD8B2; CD8b2 molecule
       3932 LCK; LCK proto-oncogene, Src family tyrosine kinase
       7535 ZAP70; zeta chain of T cell receptor associated protein kinase 70
       27040 LAT; linker for activation of T cells
       3937 LCP2; lymphocyte cytosolic protein 2
       10451 VAV3; vav guanine nucleotide exchange factor 3
       7409 VAV1; vav guanine nucleotide exchange factor 1
       7410 VAV2; vav guanine nucleotide exchange factor 2
       5335 PLCG1; phospholipase C gamma 1
       4772 NFATC1; nuclear factor of activated T cells 1
       4773 NFATC2; nuclear factor of activated T cells 2
       4775 NFATC3; nuclear factor of activated T cells 3
       3558 IL2; interleukin 2
       3586 IL10; interleukin 10
K05717 FN1; fibronectin 1
K06483 ITGA4; integrin alpha 4
K06484 ITGA5; integrin alpha 5
K05719 ITGB1; integrin beta 1
K07863 RHOG; Ras homolog gene family, member G
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K05871 PTK2B; focal adhesion kinase 2 [EC:2.7.10.2]
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K05726 BCAR1; breast cancer anti-estrogen resistance 1
K12366 ELMO1; engulfment and cell motility protein 1
K18985 ELMO2; engulfment and cell motility protein 2
K13708 DOCK1; dedicator of cytokinesis protein 1
K06856 IGH; immunoglobulin heavy chain
K06472 FCGR2A; low affinity immunoglobulin gamma Fc receptor II-a
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
K07941 ARF6; ADP-ribosylation factor 6
K23612 WASL; neural Wiskott-Aldrich syndrome protein
K17260 ACTR2; actin-related protein 2
K18584 ACTR3; actin-related protein 3
K18584 ACTR3; actin-related protein 3
K18584 ACTR3; actin-related protein 3
K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
K05758 ARPC2; actin related protein 2/3 complex, subunit 2
K05756 ARPC3; actin related protein 2/3 complex, subunit 3
K05755 ARPC4; actin related protein 2/3 complex, subunit 4
K05754 ARPC5; actin related protein 2/3 complex, subunit 5
K05754 ARPC5; actin related protein 2/3 complex, subunit 5
K05692 ACTB_G1; actin beta/gamma 1
K05692 ACTB_G1; actin beta/gamma 1
K19475 WIPF; WAS/WASL-interacting protein
K19475 WIPF; WAS/WASL-interacting protein
K19475 WIPF; WAS/WASL-interacting protein
K05627 BAIAP2; BAI1-associated protein 2
K05748 WASF2; WAS protein family, member 2
K05760 PXN; paxillin
K12487 GIT2; G protein-coupled receptor kinase interactor 2
K13710 ARHGEF7; Rho guanine nucleotide exchange factor 7
K04393 CDC42; cell division control protein 42
K05747 WAS; Wiskott-Aldrich syndrome protein
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K07532 ARHGEF12; Rho guanine nucleotide exchange factor 12
K12330 ARHGEF1; Rho guanine nucleotide exchange factor 1
K21072 ARHGEF28; A-kinase anchor protein 28
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K17698 FYB; FYN binding protein
K23471 SKAP2; src kinase-associated phosphoprotein 2
K12800 NLRP3; NACHT, LRR and PYD domains-containing protein 3
K12805 NLRC4; NLR family CARD domain-containing protein 4
K06071 PKN1; serine/threonine-protein kinase N1 [EC:2.7.11.13]
K23691 PKN2; serine/threonine-protein kinase N2 [EC:2.7.11.13]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
K12803 MEFV; pyrin
K05743 LIMK1; LIM domain kinase 1 [EC:2.7.11.1]
K12799 PYCARD; apoptosis-associated speck-like protein containing a CARD
K01370 CASP1; caspase 1 [EC:3.4.22.36]
K05482 IL18; interleukin 18
K04519 IL1B; interleukin 1 beta
K10160 TLR4; toll-like receptor 4
K04729 MYD88; myeloid differentiation primary response protein MyD88
K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K04403 MAP3K7IP1; TAK1-binding protein 1
K04404 MAP3K7IP2; TAK1-binding protein 2
K04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04432 MAP2K3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
K04433 MAP2K6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04430 MAP2K4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
K04431 MAP2K7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04379 FOS; proto-oncogene protein c-fos
K04448 JUN; transcription factor AP-1
K05842 TRIF; toll-like receptor adapter molecule 1
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K05411 IRF3; interferon regulatory factor 3
K03156 TNF; tumor necrosis factor superfamily, member 2
K05405 IL6; interleukin 6
K10030 IL8; interleukin 8
K05415 IFNB; interferon beta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K14624 CCL2; C-C motif chemokine 2
K06454 CD4; T-cell surface glycoprotein CD4
K06458 CD8A; T-cell surface glycoprotein CD8 alpha chain
K06459 CD8B; T-cell surface glycoprotein CD8 beta chain
K06459 CD8B; T-cell surface glycoprotein CD8 beta chain
K05856 LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
K07360 ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]
K07362 LAT; linker for activation of T cells
K07361 LCP2; lymphocyte cytosolic protein 2
K05730 VAV; guanine nucleotide exchange factor VAV
K05730 VAV; guanine nucleotide exchange factor VAV
K05730 VAV; guanine nucleotide exchange factor VAV
K01116 PLCG1; phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K04446 NFATC1; nuclear factor of activated T-cells, cytoplasmic 1
K17332 NFATC2; nuclear factor of activated T-cells, cytoplasmic 2
K17333 NFATC3; nuclear factor of activated T-cells, cytoplasmic 3
K05429 IL2; interleukin 2
K05443 IL10; interleukin 10
     05133 Pertussis [PATH:hsa05133]
     05134 Legionellosis [PATH:hsa05134]
     05150 Staphylococcus aureus infection [PATH:hsa05150]
     05152 Tuberculosis [PATH:hsa05152]
     05100 Bacterial invasion of epithelial cells [PATH:hsa05100]
       999 CDH1; cadherin 1
       1499 CTNNB1; catenin beta 1
       29119 CTNNA3; catenin alpha 3
       1495 CTNNA1; catenin alpha 1
       1496 CTNNA2; catenin alpha 2
       79658 ARHGAP10; Rho GTPase activating protein 10
       4233 MET; MET proto-oncogene, receptor tyrosine kinase
       2549 GAB1; GRB2 associated binding protein 1
       5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
       5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
       8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
       5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       1398 CRK; CRK proto-oncogene, adaptor protein
       1399 CRKL; CRK like proto-oncogene, adaptor protein
       1793 DOCK1; dedicator of cytokinesis 1
       998 CDC42; cell division cycle 42
       5879 RAC1; Rac family small GTPase 1
       8976 WASL; WASP like actin nucleation promoting factor
       8936 WASF1; WASP family member 1
       10163 WASF2; WASP family member 2
       10097 ACTR2; actin related protein 2
       57180 ACTR3B; actin related protein 3B
       653857 ACTR3C; actin related protein 3C
       10096 ACTR3; actin related protein 3
       10095 ARPC1B; actin related protein 2/3 complex subunit 1B
       10552 ARPC1A; actin related protein 2/3 complex subunit 1A
       10109 ARPC2; actin related protein 2/3 complex subunit 2
       10094 ARPC3; actin related protein 2/3 complex subunit 3
       10093 ARPC4; actin related protein 2/3 complex subunit 4
       10092 ARPC5; actin related protein 2/3 complex subunit 5
       81873 ARPC5L; actin related protein 2/3 complex subunit 5 like
       71 ACTG1; actin gamma 1
       60 ACTB; actin beta
       1731 SEPTIN1; septin 1
       4735 SEPTIN2; septin 2
       10801 SEPTIN9; septin 9
       124404 SEPTIN12; septin 12
       55964 SEPTIN3; septin 3
       23157 SEPTIN6; septin 6
       55752 SEPTIN11; septin 11
       23176 SEPTIN8; septin 8
       867 CBL; Cbl proto-oncogene
       6464 SHC1; SHC adaptor protein 1
       25759 SHC2; SHC adaptor protein 2
       53358 SHC3; SHC adaptor protein 3
       399694 SHC4; SHC adaptor protein 4
       23607 CD2AP; CD2 associated protein
       1759 DNM1; dynamin 1
       26052 DNM3; dynamin 3
       1785 DNM2; dynamin 2
       1211 CLTA; clathrin light chain A
       1212 CLTB; clathrin light chain B
       1213 CLTC; clathrin heavy chain
       8218 CLTCL1; clathrin heavy chain like 1
       857 CAV1; caveolin 1
       858 CAV2; caveolin 2
       859 CAV3; caveolin 3
       2017 CTTN; cortactin
       3059 HCLS1; hematopoietic cell-specific Lyn substrate 1
       6714 SRC; SRC proto-oncogene, non-receptor tyrosine kinase
       5747 PTK2; protein tyrosine kinase 2
       9564 BCAR1; BCAR1 scaffold protein, Cas family member
       5829 PXN; paxillin
       2335 FN1; fibronectin 1
       3678 ITGA5; integrin subunit alpha 5
       3688 ITGB1; integrin subunit beta 1
       3611 ILK; integrin linked kinase
       10459 MAD2L2; mitotic arrest deficient 2 like 2
       26084 ARHGEF26; Rho guanine nucleotide exchange factor 26
       391 RHOG; ras homolog family member G
       9844 ELMO1; engulfment and cell motility 1
       63916 ELMO2; engulfment and cell motility 2
       79767 ELMO3; engulfment and cell motility 3
       387 RHOA; ras homolog family member A
       7414 VCL; vinculin
K05689 CDH1; cadherin 1, type 1, E-cadherin
K02105 CTNNB1; catenin beta 1
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K05691 CTNNA; catenin alpha
K13736 ARHGAP10; Rho GTPase-activating protein 10
K05099 MET; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]
K09593 GAB1; GRB2-associated-binding protein 1
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K04438 CRK; C-crk adapter molecule crk
K04438 CRK; C-crk adapter molecule crk
K13708 DOCK1; dedicator of cytokinesis protein 1
K04393 CDC42; cell division control protein 42
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K23612 WASL; neural Wiskott-Aldrich syndrome protein
K05753 WASF1; WAS protein family, member 1
K05748 WASF2; WAS protein family, member 2
K17260 ACTR2; actin-related protein 2
K18584 ACTR3; actin-related protein 3
K18584 ACTR3; actin-related protein 3
K18584 ACTR3; actin-related protein 3
K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
K05758 ARPC2; actin related protein 2/3 complex, subunit 2
K05756 ARPC3; actin related protein 2/3 complex, subunit 3
K05755 ARPC4; actin related protein 2/3 complex, subunit 4
K05754 ARPC5; actin related protein 2/3 complex, subunit 5
K05754 ARPC5; actin related protein 2/3 complex, subunit 5
K05692 ACTB_G1; actin beta/gamma 1
K05692 ACTB_G1; actin beta/gamma 1
K13737 SEPT1; septin 1
K16942 SEPT2; septin 2
K16938 SEPT3_9_12; septin 3/9/12
K16938 SEPT3_9_12; septin 3/9/12
K16938 SEPT3_9_12; septin 3/9/12
K16939 SEPT6_8_11; septin 6/8/11
K16939 SEPT6_8_11; septin 6/8/11
K16939 SEPT6_8_11; septin 6/8/11
K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
K06279 SHC1; SHC-transforming protein 1
K17447 SHC2; SHC-transforming protein 2
K17448 SHC3; SHC-transforming protein 3
K17449 SHC4; SHC-transforming protein 4
K13738 CD2AP; CD2-associated protein
K01528 DNM1_3; dynamin 1/3 [EC:3.6.5.5]
K01528 DNM1_3; dynamin 1/3 [EC:3.6.5.5]
K23484 DNM2; dynamin 2 [EC:3.6.5.5]
K04644 CLTA; clathrin light chain A
K04645 CLTB; clathrin light chain B
K04646 CLTC; clathrin heavy chain
K04646 CLTC; clathrin heavy chain
K06278 CAV1; caveolin 1
K12958 CAV2; caveolin 2
K12959 CAV3; caveolin 3
K06106 CTTN; cortactin
K06106 CTTN; cortactin
K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
K05726 BCAR1; breast cancer anti-estrogen resistance 1
K05760 PXN; paxillin
K05717 FN1; fibronectin 1
K06484 ITGA5; integrin alpha 5
K05719 ITGB1; integrin beta 1
K06272 ILK; integrin-linked kinase [EC:2.7.11.1]
K13728 MAD2L2; mitotic spindle assembly checkpoint protein MAD2B
K13744 ARHGEF26; Rho guanine nucleotide exchange factor 26
K07863 RHOG; Ras homolog gene family, member G
K12366 ELMO1; engulfment and cell motility protein 1
K18985 ELMO2; engulfment and cell motility protein 2
K19241 ELMO3; engulfment and cell motility protein 3
K04513 RHOA; Ras homolog gene family, member A
K05700 VCL; vinculin
 
   09172 Infectious disease: viral
 
   09174 Infectious disease: parasitic
 
   09175 Drug resistance: antimicrobial
 
   09176 Drug resistance: antineoplastic
 
 09180 Brite Hierarchies
 
 09190 Not Included in Pathway or Brite

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: November 26, 2020