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KO |
 09100 Metabolism
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09120 Genetic Information Processing
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09130 Environmental Information Processing
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09140 Cellular Processes
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 09150 Organismal Systems
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09151 Immune system
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04640 Hematopoietic cell lineage [PATH:hsa04640]
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04610 Complement and coagulation cascades [PATH:hsa04610]
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04611 Platelet activation [PATH:hsa04611]
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04613 Neutrophil extracellular trap formation [PATH:hsa04613]
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04620 Toll-like receptor signaling pathway [PATH:hsa04620]
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 04624 Toll and Imd signaling pathway
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04621 NOD-like receptor signaling pathway [PATH:hsa04621]
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04622 RIG-I-like receptor signaling pathway [PATH:hsa04622]
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23586 DDX58; DExD/H-box helicase 58
64135 IFIH1; interferon induced with helicase C domain 1
57506 MAVS; mitochondrial antiviral signaling protein
79132 DHX58; DExH-box helicase 58
7187 TRAF3; TNF receptor associated factor 3
10010 TANK; TRAF family member associated NFKB activator
64343 AZI2; 5-azacytidine induced 2
9755 TBKBP1; TBK1 binding protein 1
8517 IKBKG; inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
29110 TBK1; TANK binding kinase 1
9641 IKBKE; inhibitor of nuclear factor kappa B kinase subunit epsilon
3661 IRF3; interferon regulatory factor 3
3665 IRF7; interferon regulatory factor 7
3439 IFNA1; interferon alpha 1
3440 IFNA2; interferon alpha 2
3441 IFNA4; interferon alpha 4
3442 IFNA5; interferon alpha 5
3443 IFNA6; interferon alpha 6
3444 IFNA7; interferon alpha 7
3445 IFNA8; interferon alpha 8
3446 IFNA10; interferon alpha 10
3447 IFNA13; interferon alpha 13
3448 IFNA14; interferon alpha 14
3449 IFNA16; interferon alpha 16
3451 IFNA17; interferon alpha 17
3452 IFNA21; interferon alpha 21
3456 IFNB1; interferon beta 1
3467 IFNW1; interferon omega 1
338376 IFNE; interferon epsilon
56832 IFNK; interferon kappa
8717 TRADD; TNFRSF1A associated via death domain
8772 FADD; Fas associated via death domain
8737 RIPK1; receptor interacting serine/threonine kinase 1
841 CASP8; caspase 8
843 CASP10; caspase 10
1147 CHUK; component of inhibitor of nuclear factor kappa B kinase complex
3551 IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta
4793 NFKBIB; NFKB inhibitor beta
4792 NFKBIA; NFKB inhibitor alpha
4790 NFKB1; nuclear factor kappa B subunit 1
5970 RELA; RELA proto-oncogene, NF-kB subunit
7186 TRAF2; TNF receptor associated factor 2
6885 MAP3K7; mitogen-activated protein kinase kinase kinase 7
7189 TRAF6; TNF receptor associated factor 6
4214 MAP3K1; mitogen-activated protein kinase kinase kinase 1
5599 MAPK8; mitogen-activated protein kinase 8
5602 MAPK10; mitogen-activated protein kinase 10
5601 MAPK9; mitogen-activated protein kinase 9
5600 MAPK11; mitogen-activated protein kinase 11
6300 MAPK12; mitogen-activated protein kinase 12
5603 MAPK13; mitogen-activated protein kinase 13
1432 MAPK14; mitogen-activated protein kinase 14
3576 CXCL8; C-X-C motif chemokine ligand 8
7124 TNF; tumor necrosis factor
3592 IL12A; interleukin 12A
3593 IL12B; interleukin 12B
3627 CXCL10; C-X-C motif chemokine ligand 10
7706 TRIM25; tripartite motif containing 25
1540 CYLD; CYLD lysine 63 deubiquitinase
54941 RNF125; ring finger protein 125
9636 ISG15; ISG15 ubiquitin like modifier
9474 ATG5; autophagy related 5
9140 ATG12; autophagy related 12
79671 NLRX1; NLR family member X1
340061 STING1; stimulator of interferon response cGAMP interactor 1
55593 OTUD5; OTU deubiquitinase 5
80143 SIKE1; suppressor of IKBKE 1
1654 DDX3X; DEAD-box helicase 3 X-linked
5300 PIN1; peptidylprolyl cis/trans isomerase, NIMA-interacting 1
26007 TKFC; triokinase and FMN cyclase
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K12646 DDX58; ATP-dependent RNA helicase DDX58 [EC:3.6.4.13]
K12647 IFIH1; interferon-induced helicase C domain-containing protein 1 [EC:3.6.4.13]
K12648 MAVS; mitochondrial antiviral-signaling protein
K12649 DHX58; ATP-dependent RNA helicase DHX58 [EC:3.6.4.13]
K03174 TRAF3; TNF receptor-associated factor 3
K12650 TANK; TRAF family member-associated NF-kappa-B activator
K12651 AZI2; 5-azacytidine-induced protein 2
K12652 TBKBP1; TANK-binding kinase 1-binding protein
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
K07211 IKBKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]
K05411 IRF3; interferon regulatory factor 3
K09447 IRF7; interferon regulatory factor 7
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K05440 IFNW; interferon omega
K05442 IFNE; interferon epsilon
K05441 IFNK; interferon kappa
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K02373 FADD; FAS-associated death domain protein
K02861 RIPK1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04400 CASP10; caspase 10 [EC:3.4.22.63]
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K02581 NFKBIB; NF-kappa-B inhibitor beta
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
K04416 MAP3K1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K10030 IL8; interleukin 8
K03156 TNF; tumor necrosis factor superfamily, member 2
K05406 IL12A; interleukin 12A
K05425 IL12B; interleukin 12B
K12671 CXCL10; C-X-C motif chemokine 10
K10652 TRIM25; tripartite motif-containing protein 25 [EC:2.3.2.27]
K08601 CYLD; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]
K12170 RNF125; E3 ubiquitin-protein ligase RNF125 [EC:2.3.2.27]
K12159 ISG15; ubiquitin cross-reactive protein
K08339 ATG5; autophagy-related protein 5
K08336 ATG12; ubiquitin-like protein ATG12
K12653 NLRX1; NLR family member X1
K12654 TMEM173; transmembrane protein 173
K12655 OTUD5; OTU domain-containing protein 5 [EC:3.4.19.12]
K12656 SIKE; suppressor of IKK-epsilon
K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:3.6.4.13]
K09578 PIN1; peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 [EC:5.2.1.8]
K00863 DAK; triose/dihydroxyacetone kinase / FAD-AMP lyase (cyclizing) [EC:2.7.1.28 2.7.1.29 4.6.1.15]
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04623 Cytosolic DNA-sensing pathway [PATH:hsa04623]
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04625 C-type lectin receptor signaling pathway [PATH:hsa04625]
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04650 Natural killer cell mediated cytotoxicity [PATH:hsa04650]
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04612 Antigen processing and presentation [PATH:hsa04612]
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04660 T cell receptor signaling pathway [PATH:hsa04660]
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04658 Th1 and Th2 cell differentiation [PATH:hsa04658]
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04659 Th17 cell differentiation [PATH:hsa04659]
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04657 IL-17 signaling pathway [PATH:hsa04657]
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04662 B cell receptor signaling pathway [PATH:hsa04662]
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04664 Fc epsilon RI signaling pathway [PATH:hsa04664]
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04666 Fc gamma R-mediated phagocytosis [PATH:hsa04666]
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04670 Leukocyte transendothelial migration [PATH:hsa04670]
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04672 Intestinal immune network for IgA production [PATH:hsa04672]
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04062 Chemokine signaling pathway [PATH:hsa04062]
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09152 Endocrine system
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09153 Circulatory system
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09154 Digestive system
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09155 Excretory system
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09156 Nervous system
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09157 Sensory system
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09158 Development and regeneration
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09149 Aging
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09159 Environmental adaptation
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09160 Human Diseases
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09180 Brite Hierarchies
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09190 Not Included in Pathway or Brite
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KEGG Orthology (KO) - Homo sapiens (human)