KEGG Orthology (KO) - Homo sapiens (human)

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     KO
 09100 Metabolism
 
   09101 Carbohydrate metabolism
 
   09102 Energy metabolism
 
   09103 Lipid metabolism
     00061 Fatty acid biosynthesis [PATH:hsa00061]
     00062 Fatty acid elongation [PATH:hsa00062]
     00071 Fatty acid degradation [PATH:hsa00071]
     00072 Synthesis and degradation of ketone bodies [PATH:hsa00072]
     00073 Cutin, suberine and wax biosynthesis
     00100 Steroid biosynthesis [PATH:hsa00100]
     00120 Primary bile acid biosynthesis [PATH:hsa00120]
     00121 Secondary bile acid biosynthesis
     00140 Steroid hormone biosynthesis [PATH:hsa00140]
     00561 Glycerolipid metabolism [PATH:hsa00561]
     00564 Glycerophospholipid metabolism [PATH:hsa00564]
     00565 Ether lipid metabolism [PATH:hsa00565]
     00600 Sphingolipid metabolism [PATH:hsa00600]
       10558 SPTLC1; serine palmitoyltransferase long chain base subunit 1
       9517 SPTLC2; serine palmitoyltransferase long chain base subunit 2
       55304 SPTLC3; serine palmitoyltransferase long chain base subunit 3
       2531 KDSR; 3-ketodihydrosphingosine reductase
       10715 CERS1; ceramide synthase 1
       29956 CERS2; ceramide synthase 2
       79603 CERS4; ceramide synthase 4
       204219 CERS3; ceramide synthase 3
       253782 CERS6; ceramide synthase 6
       91012 CERS5; ceramide synthase 5
       427 ASAH1; N-acylsphingosine amidohydrolase 1
       56624 ASAH2; N-acylsphingosine amidohydrolase 2
       340485 ACER2; alkaline ceramidase 2
       125981 ACER1; alkaline ceramidase 1
       55331 ACER3; alkaline ceramidase 3
       8560 DEGS1; delta 4-desaturase, sphingolipid 1
       123099 DEGS2; delta 4-desaturase, sphingolipid 2
       259230 SGMS1; sphingomyelin synthase 1
       166929 SGMS2; sphingomyelin synthase 2
       6609 SMPD1; sphingomyelin phosphodiesterase 1
       6610 SMPD2; sphingomyelin phosphodiesterase 2
       55512 SMPD3; sphingomyelin phosphodiesterase 3
       55627 SMPD4; sphingomyelin phosphodiesterase 4
       339221 ENPP7; ectonucleotide pyrophosphatase/phosphodiesterase 7
       64781 CERK; ceramide kinase
       8611 PLPP1; phospholipid phosphatase 1
       8613 PLPP3; phospholipid phosphatase 3
       8612 PLPP2; phospholipid phosphatase 2
       81537 SGPP1; sphingosine-1-phosphate phosphatase 1
       130367 SGPP2; sphingosine-1-phosphate phosphatase 2
       8877 SPHK1; sphingosine kinase 1
       56848 SPHK2; sphingosine kinase 2
       8879 SGPL1; sphingosine-1-phosphate lyase 1
       7357 UGCG; UDP-glucose ceramide glucosyltransferase
       2629 GBA; glucosylceramidase beta
       57704 GBA2; glucosylceramidase beta 2
       9331 B4GALT6; beta-1,4-galactosyltransferase 6
       2720 GLB1; galactosidase beta 1
       7368 UGT8; UDP glycosyltransferase 8
       2581 GALC; galactosylceramidase
       9514 GAL3ST1; galactose-3-O-sulfotransferase 1
       410 ARSA; arylsulfatase A
       4758 NEU1; neuraminidase 1
       10825 NEU3; neuraminidase 3
       129807 NEU4; neuraminidase 4
       4759 NEU2; neuraminidase 2
       2717 GLA; galactosidase alpha
       5660 PSAP; prosaposin
       768239 PSAPL1; prosaposin like 1
K00654 SPT; serine palmitoyltransferase [EC:2.3.1.50]
K00654 SPT; serine palmitoyltransferase [EC:2.3.1.50]
K00654 SPT; serine palmitoyltransferase [EC:2.3.1.50]
K04708 KDSR; 3-dehydrosphinganine reductase [EC:1.1.1.102]
K04710 CERS1; sphingoid base N-stearoyltransferase [EC:2.3.1.299]
K24621 CERS2_4; very-long-chain ceramide synthase [EC:2.3.1.297]
K24621 CERS2_4; very-long-chain ceramide synthase [EC:2.3.1.297]
K24622 CERS3; very-long-chain ceramide synthase / ultra-long-chain ceramide synthase [EC:2.3.1.297 2.3.1.298]
K23727 CERS5_6; sphingoid base N-palmitoyltransferase [EC:2.3.1.291]
K23727 CERS5_6; sphingoid base N-palmitoyltransferase [EC:2.3.1.291]
K12348 ASAH1; acid ceramidase [EC:3.5.1.23]
K12349 ASAH2; neutral ceramidase [EC:3.5.1.23]
K01441 ACER1_2; alkaline ceramidase [EC:3.5.1.23]
K01441 ACER1_2; alkaline ceramidase [EC:3.5.1.23]
K04711 ACER3; dihydroceramidase [EC:3.5.1.-]
K04712 DEGS; sphingolipid 4-desaturase/C4-monooxygenase [EC:1.14.19.17 1.14.18.5]
K04712 DEGS; sphingolipid 4-desaturase/C4-monooxygenase [EC:1.14.19.17 1.14.18.5]
K04714 SGMS; shingomyelin synthase [EC:2.7.8.27]
K04714 SGMS; shingomyelin synthase [EC:2.7.8.27]
K12350 SMPD1; sphingomyelin phosphodiesterase [EC:3.1.4.12]
K12351 SMPD2; sphingomyelin phosphodiesterase 2 [EC:3.1.4.12]
K12352 SMPD3; sphingomyelin phosphodiesterase 3 [EC:3.1.4.12]
K12353 SMPD4; sphingomyelin phosphodiesterase 4 [EC:3.1.4.12]
K12354 ENPP7; ectonucleotide pyrophosphatase/phosphodiesterase family member 7 [EC:3.1.4.12]
K04715 CERK; ceramide kinase [EC:2.7.1.138]
K01080 PLPP1_2_3; phosphatidate phosphatase [EC:3.1.3.4]
K01080 PLPP1_2_3; phosphatidate phosphatase [EC:3.1.3.4]
K01080 PLPP1_2_3; phosphatidate phosphatase [EC:3.1.3.4]
K04716 SGPP1; sphingosine-1-phosphate phosphatase 1 [EC:3.1.3.-]
K04717 SGPP2; sphingosine-1-phosphate phosphotase 2 [EC:3.1.3.-]
K04718 SPHK; sphingosine kinase [EC:2.7.1.91]
K04718 SPHK; sphingosine kinase [EC:2.7.1.91]
K01634 SGPL1; sphinganine-1-phosphate aldolase [EC:4.1.2.27]
K00720 UGCG; ceramide glucosyltransferase [EC:2.4.1.80]
K01201 GBA; glucosylceramidase [EC:3.2.1.45]
K17108 GBA2; non-lysosomal glucosylceramidase [EC:3.2.1.45]
K07553 B4GALT6; beta-1,4-galactosyltransferase 6 [EC:2.4.1.274]
K12309 GLB1; beta-galactosidase [EC:3.2.1.23]
K04628 CGT; ceramide galactosyltransferase [EC:2.4.1.47]
K01202 GALC; galactosylceramidase [EC:3.2.1.46]
K01019 GAL3ST1; galactosylceramide sulfotransferase [EC:2.8.2.11]
K01134 ARSA; arylsulfatase A [EC:3.1.6.8]
K01186 NEU1; sialidase-1 [EC:3.2.1.18]
K12357 NEU2_3_4; sialidase-2/3/4 [EC:3.2.1.18]
K12357 NEU2_3_4; sialidase-2/3/4 [EC:3.2.1.18]
K12357 NEU2_3_4; sialidase-2/3/4 [EC:3.2.1.18]
K01189 GLA; alpha-galactosidase [EC:3.2.1.22]
K12382 PSAP; saposin
K12382 PSAP; saposin
     00590 Arachidonic acid metabolism [PATH:hsa00590]
     00591 Linoleic acid metabolism [PATH:hsa00591]
     00592 alpha-Linolenic acid metabolism [PATH:hsa00592]
     01040 Biosynthesis of unsaturated fatty acids [PATH:hsa01040]
 
   09104 Nucleotide metabolism
 
   09105 Amino acid metabolism
 
   09106 Metabolism of other amino acids
 
   09107 Glycan biosynthesis and metabolism
 
   09108 Metabolism of cofactors and vitamins
 
   09109 Metabolism of terpenoids and polyketides
 
   09110 Biosynthesis of other secondary metabolites
 
   09111 Xenobiotics biodegradation and metabolism
 
   09112 Not included in regular maps
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
   09131 Membrane transport
 
   09132 Signal transduction
     02020 Two-component system
     04010 MAPK signaling pathway [PATH:hsa04010]
     04013 MAPK signaling pathway - fly
     04016 MAPK signaling pathway - plant
     04011 MAPK signaling pathway - yeast
     04012 ErbB signaling pathway [PATH:hsa04012]
     04014 Ras signaling pathway [PATH:hsa04014]
     04015 Rap1 signaling pathway [PATH:hsa04015]
     04310 Wnt signaling pathway [PATH:hsa04310]
     04330 Notch signaling pathway [PATH:hsa04330]
     04340 Hedgehog signaling pathway [PATH:hsa04340]
     04341 Hedgehog signaling pathway - fly
     04350 TGF-beta signaling pathway [PATH:hsa04350]
     04390 Hippo signaling pathway [PATH:hsa04390]
     04391 Hippo signaling pathway - fly
     04392 Hippo signaling pathway - multiple species [PATH:hsa04392]
     04370 VEGF signaling pathway [PATH:hsa04370]
     04371 Apelin signaling pathway [PATH:hsa04371]
     04630 JAK-STAT signaling pathway [PATH:hsa04630]
     04064 NF-kappa B signaling pathway [PATH:hsa04064]
     04668 TNF signaling pathway [PATH:hsa04668]
     04066 HIF-1 signaling pathway [PATH:hsa04066]
     04068 FoxO signaling pathway [PATH:hsa04068]
     04020 Calcium signaling pathway [PATH:hsa04020]
     04070 Phosphatidylinositol signaling system [PATH:hsa04070]
     04072 Phospholipase D signaling pathway [PATH:hsa04072]
     04071 Sphingolipid signaling pathway [PATH:hsa04071]
       10558 SPTLC1; serine palmitoyltransferase long chain base subunit 1
       9517 SPTLC2; serine palmitoyltransferase long chain base subunit 2
       55304 SPTLC3; serine palmitoyltransferase long chain base subunit 3
       10715 CERS1; ceramide synthase 1
       29956 CERS2; ceramide synthase 2
       79603 CERS4; ceramide synthase 4
       204219 CERS3; ceramide synthase 3
       253782 CERS6; ceramide synthase 6
       91012 CERS5; ceramide synthase 5
       8560 DEGS1; delta 4-desaturase, sphingolipid 1
       123099 DEGS2; delta 4-desaturase, sphingolipid 2
       6609 SMPD1; sphingomyelin phosphodiesterase 1
       259230 SGMS1; sphingomyelin synthase 1
       166929 SGMS2; sphingomyelin synthase 2
       7124 TNF; tumor necrosis factor
       7132 TNFRSF1A; TNF receptor superfamily member 1A
       8439 NSMAF; neutral sphingomyelinase activation associated factor
       6610 SMPD2; sphingomyelin phosphodiesterase 2
       427 ASAH1; N-acylsphingosine amidohydrolase 1
       56624 ASAH2; N-acylsphingosine amidohydrolase 2
       340485 ACER2; alkaline ceramidase 2
       125981 ACER1; alkaline ceramidase 1
       8717 TRADD; TNFRSF1A associated via death domain
       7186 TRAF2; TNF receptor associated factor 2
       1509 CTSD; cathepsin D
       637 BID; BH3 interacting domain death agonist
       581 BAX; BCL2 associated X, apoptosis regulator
       4217 MAP3K5; mitogen-activated protein kinase kinase kinase 5
       5599 MAPK8; mitogen-activated protein kinase 8
       5602 MAPK10; mitogen-activated protein kinase 10
       5601 MAPK9; mitogen-activated protein kinase 9
       5600 MAPK11; mitogen-activated protein kinase 11
       6300 MAPK12; mitogen-activated protein kinase 12
       5603 MAPK13; mitogen-activated protein kinase 13
       1432 MAPK14; mitogen-activated protein kinase 14
       5590 PRKCZ; protein kinase C zeta
       207 AKT1; AKT serine/threonine kinase 1
       208 AKT2; AKT serine/threonine kinase 2
       10000 AKT3; AKT serine/threonine kinase 3
       596 BCL2; BCL2 apoptosis regulator
       5515 PPP2CA; protein phosphatase 2 catalytic subunit alpha
       5516 PPP2CB; protein phosphatase 2 catalytic subunit beta
       5519 PPP2R1B; protein phosphatase 2 scaffold subunit Abeta
       5518 PPP2R1A; protein phosphatase 2 scaffold subunit Aalpha
       5520 PPP2R2A; protein phosphatase 2 regulatory subunit Balpha
       5521 PPP2R2B; protein phosphatase 2 regulatory subunit Bbeta
       5522 PPP2R2C; protein phosphatase 2 regulatory subunit Bgamma
       55844 PPP2R2D; protein phosphatase 2 regulatory subunit Bdelta
       28227 PPP2R3B; protein phosphatase 2 regulatory subunit B''beta
       55012 PPP2R3C; protein phosphatase 2 regulatory subunit B''gamma
       5523 PPP2R3A; protein phosphatase 2 regulatory subunit B''alpha
       5526 PPP2R5B; protein phosphatase 2 regulatory subunit B'beta
       5527 PPP2R5C; protein phosphatase 2 regulatory subunit B'gamma
       5528 PPP2R5D; protein phosphatase 2 regulatory subunit B'delta
       5529 PPP2R5E; protein phosphatase 2 regulatory subunit B'epsilon
       5525 PPP2R5A; protein phosphatase 2 regulatory subunit B'alpha
       7157 TP53; tumor protein p53
       2205 FCER1A; Fc fragment of IgE receptor Ia
       2206 MS4A2; membrane spanning 4-domains A2
       2207 FCER1G; Fc fragment of IgE receptor Ig
       2534 FYN; FYN proto-oncogene, Src family tyrosine kinase
       9846 GAB2; GRB2 associated binding protein 2
       5290 PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
       5293 PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
       5291 PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
       5295 PIK3R1; phosphoinositide-3-kinase regulatory subunit 1
       5296 PIK3R2; phosphoinositide-3-kinase regulatory subunit 2
       8503 PIK3R3; phosphoinositide-3-kinase regulatory subunit 3
       5337 PLD1; phospholipase D1
       5338 PLD2; phospholipase D2
       8877 SPHK1; sphingosine kinase 1
       56848 SPHK2; sphingosine kinase 2
       3827 KNG1; kininogen 1
       134 ADORA1; adenosine A1 receptor
       140 ADORA3; adenosine A3 receptor
       624 BDKRB2; bradykinin receptor B2
       4985 OPRD1; opioid receptor delta 1
       2770 GNAI1; G protein subunit alpha i1
       2773 GNAI3; G protein subunit alpha i3
       2771 GNAI2; G protein subunit alpha i2
       23236 PLCB1; phospholipase C beta 1
       5330 PLCB2; phospholipase C beta 2
       5331 PLCB3; phospholipase C beta 3
       5332 PLCB4; phospholipase C beta 4
       5581 PRKCE; protein kinase C epsilon
       5594 MAPK1; mitogen-activated protein kinase 1
       5595 MAPK3; mitogen-activated protein kinase 3
       81537 SGPP1; sphingosine-1-phosphate phosphatase 1
       130367 SGPP2; sphingosine-1-phosphate phosphatase 2
       4363 ABCC1; ATP binding cassette subfamily C member 1
       8879 SGPL1; sphingosine-1-phosphate lyase 1
       1901 S1PR1; sphingosine-1-phosphate receptor 1
       9294 S1PR2; sphingosine-1-phosphate receptor 2
       3265 HRAS; HRas proto-oncogene, GTPase
       3845 KRAS; KRAS proto-oncogene, GTPase
       4893 NRAS; NRAS proto-oncogene, GTPase
       5894 RAF1; Raf-1 proto-oncogene, serine/threonine kinase
       5604 MAP2K1; mitogen-activated protein kinase kinase 1
       5605 MAP2K2; mitogen-activated protein kinase kinase 2
       5170 PDPK1; 3-phosphoinositide dependent protein kinase 1
       4846 NOS3; nitric oxide synthase 3
       5879 RAC1; Rac family small GTPase 1
       5880 RAC2; Rac family small GTPase 2
       5881 RAC3; Rac family small GTPase 3
       1903 S1PR3; sphingosine-1-phosphate receptor 3
       2776 GNAQ; G protein subunit alpha q
       5578 PRKCA; protein kinase C alpha
       5579 PRKCB; protein kinase C beta
       5582 PRKCG; protein kinase C gamma
       8698 S1PR4; sphingosine-1-phosphate receptor 4
       53637 S1PR5; sphingosine-1-phosphate receptor 5
       2768 GNA12; G protein subunit alpha 12
       10672 GNA13; G protein subunit alpha 13
       387 RHOA; ras homolog family member A
       6093 ROCK1; Rho associated coiled-coil containing protein kinase 1
       9475 ROCK2; Rho associated coiled-coil containing protein kinase 2
       5728 PTEN; phosphatase and tensin homolog
       4790 NFKB1; nuclear factor kappa B subunit 1
       5970 RELA; RELA proto-oncogene, NF-kB subunit
K00654 SPT; serine palmitoyltransferase [EC:2.3.1.50]
K00654 SPT; serine palmitoyltransferase [EC:2.3.1.50]
K00654 SPT; serine palmitoyltransferase [EC:2.3.1.50]
K04710 CERS1; sphingoid base N-stearoyltransferase [EC:2.3.1.299]
K24621 CERS2_4; very-long-chain ceramide synthase [EC:2.3.1.297]
K24621 CERS2_4; very-long-chain ceramide synthase [EC:2.3.1.297]
K24622 CERS3; very-long-chain ceramide synthase / ultra-long-chain ceramide synthase [EC:2.3.1.297 2.3.1.298]
K23727 CERS5_6; sphingoid base N-palmitoyltransferase [EC:2.3.1.291]
K23727 CERS5_6; sphingoid base N-palmitoyltransferase [EC:2.3.1.291]
K04712 DEGS; sphingolipid 4-desaturase/C4-monooxygenase [EC:1.14.19.17 1.14.18.5]
K04712 DEGS; sphingolipid 4-desaturase/C4-monooxygenase [EC:1.14.19.17 1.14.18.5]
K12350 SMPD1; sphingomyelin phosphodiesterase [EC:3.1.4.12]
K04714 SGMS; shingomyelin synthase [EC:2.7.8.27]
K04714 SGMS; shingomyelin synthase [EC:2.7.8.27]
K03156 TNF; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A; tumor necrosis factor receptor superfamily member 1A
K18953 NSMAF; factor associated with neutral sphingomyelinase activation
K12351 SMPD2; sphingomyelin phosphodiesterase 2 [EC:3.1.4.12]
K12348 ASAH1; acid ceramidase [EC:3.5.1.23]
K12349 ASAH2; neutral ceramidase [EC:3.5.1.23]
K01441 ACER1_2; alkaline ceramidase [EC:3.5.1.23]
K01441 ACER1_2; alkaline ceramidase [EC:3.5.1.23]
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K01379 CTSD; cathepsin D [EC:3.4.23.5]
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K04426 MAP3K5; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K04441 P38; p38 MAP kinase [EC:2.7.11.24]
K18952 PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K02161 BCL2; apoptosis regulator Bcl-2
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
K04451 TP53; tumor protein p53
K08089 FCER1A; high affinity immunoglobulin epsilon receptor subunit alpha
K08090 MS4A2; high affinity immunoglobulin epsilon receptor subunit beta
K07983 FCER1G; high affinity immunoglobulin epsilon receptor subunit gamma
K05703 FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]
K08091 GAB2; GRB2-associated-binding protein 2
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
K04718 SPHK; sphingosine kinase [EC:2.7.1.91]
K04718 SPHK; sphingosine kinase [EC:2.7.1.91]
K03898 KNG; kininogen
K04265 ADORA1; adenosine receptor A1
K04268 ADORA3; adenosine receptor A3
K03916 BDKRB2; bradykinin receptor B2
K04213 OPRD1; delta-type opioid receptor
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05858 PLCB; phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04716 SGPP1; sphingosine-1-phosphate phosphatase 1 [EC:3.1.3.-]
K04717 SGPP2; sphingosine-1-phosphate phosphotase 2 [EC:3.1.3.-]
K05665 ABCC1; ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3]
K01634 SGPL1; sphinganine-1-phosphate aldolase [EC:4.1.2.27]
K04288 S1PR1; sphingosine 1-phosphate receptor 1
K04292 S1PR2; sphingosine 1-phosphate receptor 2
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K13242 NOS3; nitric-oxide synthase, endothelial [EC:1.14.13.39]
K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
K04290 S1PR3; sphingosine 1-phosphate receptor 3
K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
K19663 PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]
K04293 S1PR4; sphingosine 1-phosphate receptor 4
K04295 S1PR5; sphingosine 1-phosphate receptor 5
K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
K04513 RHOA; Ras homolog gene family, member A
K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
K17388 ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.1]
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
     04024 cAMP signaling pathway [PATH:hsa04024]
     04022 cGMP-PKG signaling pathway [PATH:hsa04022]
     04151 PI3K-Akt signaling pathway [PATH:hsa04151]
     04152 AMPK signaling pathway [PATH:hsa04152]
     04150 mTOR signaling pathway [PATH:hsa04150]
     04075 Plant hormone signal transduction
 
   09133 Signaling molecules and interaction
 
 09140 Cellular Processes
 
   09141 Transport and catabolism
     04144 Endocytosis [PATH:hsa04144]
     04145 Phagosome [PATH:hsa04145]
     04142 Lysosome [PATH:hsa04142]
       10312 TCIRG1; T cell immune regulator 1, ATPase H+ transporting V0 subunit a3
       23545 ATP6V0A2; ATPase H+ transporting V0 subunit a2
       50617 ATP6V0A4; ATPase H+ transporting V0 subunit a4
       535 ATP6V0A1; ATPase H+ transporting V0 subunit a1
       9114 ATP6V0D1; ATPase H+ transporting V0 subunit d1
       245972 ATP6V0D2; ATPase H+ transporting V0 subunit d2
       51606 ATP6V1H; ATPase H+ transporting V1 subunit H
       537 ATP6AP1; ATPase H+ transporting accessory protein 1
       527 ATP6V0C; ATPase H+ transporting V0 subunit c
       533 ATP6V0B; ATPase H+ transporting V0 subunit b
       5476 CTSA; cathepsin A
       1508 CTSB; cathepsin B
       1075 CTSC; cathepsin C
       1509 CTSD; cathepsin D
       1510 CTSE; cathepsin E
       8722 CTSF; cathepsin F
       1511 CTSG; cathepsin G
       1512 CTSH; cathepsin H
       1513 CTSK; cathepsin K
       1514 CTSL; cathepsin L
       1519 CTSO; cathepsin O
       1520 CTSS; cathepsin S
       1515 CTSV; cathepsin V
       1521 CTSW; cathepsin W
       1522 CTSZ; cathepsin Z
       9476 NAPSA; napsin A aspartic peptidase
       5641 LGMN; legumain
       1200 TPP1; tripeptidyl peptidase 1
       2717 GLA; galactosidase alpha
       2720 GLB1; galactosidase beta 1
       2548 GAA; glucosidase alpha, acid
       2629 GBA; glucosylceramidase beta
       3425 IDUA; alpha-L-iduronidase
       4668 NAGA; alpha-N-acetylgalactosaminidase
       4669 NAGLU; N-acetyl-alpha-glucosaminidase
       2581 GALC; galactosylceramidase
       2990 GUSB; glucuronidase beta
       2517 FUCA1; alpha-L-fucosidase 1
       2519 FUCA2; alpha-L-fucosidase 2
       3073 HEXA; hexosaminidase subunit alpha
       3074 HEXB; hexosaminidase subunit beta
       4126 MANBA; mannosidase beta
       4125 MAN2B1; mannosidase alpha class 2B member 1
       4758 NEU1; neuraminidase 1
       8692 HYAL2; hyaluronidase 2
       3373 HYAL1; hyaluronidase 1
       6677 SPAM1; sperm adhesion molecule 1
       23553 HYAL4; hyaluronidase 4
       8372 HYAL3; hyaluronidase 3
       410 ARSA; arylsulfatase A
       411 ARSB; arylsulfatase B
       22901 ARSG; arylsulfatase G
       2588 GALNS; galactosamine (N-acetyl)-6-sulfatase
       2799 GNS; glucosamine (N-acetyl)-6-sulfatase
       3423 IDS; iduronate 2-sulfatase
       6448 SGSH; N-sulfoglucosamine sulfohydrolase
       3988 LIPA; lipase A, lysosomal acid type
       23659 PLA2G15; phospholipase A2 group XV
       1777 DNASE2; deoxyribonuclease 2, lysosomal
       58511 DNASE2B; deoxyribonuclease 2 beta
       53 ACP2; acid phosphatase 2, lysosomal
       54 ACP5; acid phosphatase 5, tartrate resistant
       6609 SMPD1; sphingomyelin phosphodiesterase 1
       427 ASAH1; N-acylsphingosine amidohydrolase 1
       175 AGA; aspartylglucosaminidase
       5660 PSAP; prosaposin
       768239 PSAPL1; prosaposin like 1
       2760 GM2A; GM2 ganglioside activator
       5538 PPT1; palmitoyl-protein thioesterase 1
       9374 PPT2; palmitoyl-protein thioesterase 2
       3916 LAMP1; lysosomal associated membrane protein 1
       3920 LAMP2; lysosomal associated membrane protein 2
       27074 LAMP3; lysosomal associated membrane protein 3
       968 CD68; CD68 molecule
       967 CD63; CD63 molecule
       950 SCARB2; scavenger receptor class B member 2
       4864 NPC1; NPC intracellular cholesterol transporter 1
       10577 NPC2; NPC intracellular cholesterol transporter 2
       1497 CTNS; cystinosin, lysosomal cystine transporter
       26503 SLC17A5; solute carrier family 17 member 5
       6556 SLC11A1; solute carrier family 11 member 1
       4891 SLC11A2; solute carrier family 11 member 2
       55353 LAPTM4B; lysosomal protein transmembrane 4 beta
       7805 LAPTM5; lysosomal protein transmembrane 5
       9741 LAPTM4A; lysosomal protein transmembrane 4 alpha
       20 ABCA2; ATP binding cassette subfamily A member 2
       23457 ABCB9; ATP binding cassette subfamily B member 9
       8763 CD164; CD164 molecule
       9583 ENTPD4; ectonucleoside triphosphate diphosphohydrolase 4
       6272 SORT1; sortilin 1
       1201 CLN3; CLN3 lysosomal/endosomal transmembrane protein, battenin
       1203 CLN5; CLN5 intracellular trafficking protein
       256471 MFSD8; major facilitator superfamily domain containing 8
       138050 HGSNAT; heparan-alpha-glucosaminide N-acetyltransferase
       285362 SUMF1; sulfatase modifying factor 1
       79158 GNPTAB; N-acetylglucosamine-1-phosphate transferase subunits alpha and beta
       84572 GNPTG; N-acetylglucosamine-1-phosphate transferase subunit gamma
       51172 NAGPA; N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
       3482 IGF2R; insulin like growth factor 2 receptor
       4074 M6PR; mannose-6-phosphate receptor, cation dependent
       1211 CLTA; clathrin light chain A
       1212 CLTB; clathrin light chain B
       1213 CLTC; clathrin heavy chain
       8218 CLTCL1; clathrin heavy chain like 1
       164 AP1G1; adaptor related protein complex 1 subunit gamma 1
       8906 AP1G2; adaptor related protein complex 1 subunit gamma 2
       162 AP1B1; adaptor related protein complex 1 subunit beta 1
       8907 AP1M1; adaptor related protein complex 1 subunit mu 1
       10053 AP1M2; adaptor related protein complex 1 subunit mu 2
       1174 AP1S1; adaptor related protein complex 1 subunit sigma 1
       8905 AP1S2; adaptor related protein complex 1 subunit sigma 2
       130340 AP1S3; adaptor related protein complex 1 subunit sigma 3
       8943 AP3D1; adaptor related protein complex 3 subunit delta 1
       8120 AP3B2; adaptor related protein complex 3 subunit beta 2
       8546 AP3B1; adaptor related protein complex 3 subunit beta 1
       26985 AP3M1; adaptor related protein complex 3 subunit mu 1
       10947 AP3M2; adaptor related protein complex 3 subunit mu 2
       10239 AP3S2; adaptor related protein complex 3 subunit sigma 2
       1176 AP3S1; adaptor related protein complex 3 subunit sigma 1
       23431 AP4E1; adaptor related protein complex 4 subunit epsilon 1
       10717 AP4B1; adaptor related protein complex 4 subunit beta 1
       9179 AP4M1; adaptor related protein complex 4 subunit mu 1
       11154 AP4S1; adaptor related protein complex 4 subunit sigma 1
       23062 GGA2; golgi associated, gamma adaptin ear containing, ARF binding protein 2
       23163 GGA3; golgi associated, gamma adaptin ear containing, ARF binding protein 3
       26088 GGA1; golgi associated, gamma adaptin ear containing, ARF binding protein 1
       57192 MCOLN1; mucolipin TRP cation channel 1
       9516 LITAF; lipopolysaccharide induced TNF factor
K02154 ATPeV0A; V-type H+-transporting ATPase subunit a
K02154 ATPeV0A; V-type H+-transporting ATPase subunit a
K02154 ATPeV0A; V-type H+-transporting ATPase subunit a
K02154 ATPeV0A; V-type H+-transporting ATPase subunit a
K02146 ATPeV0D; V-type H+-transporting ATPase subunit d
K02146 ATPeV0D; V-type H+-transporting ATPase subunit d
K02144 ATPeV1H; V-type H+-transporting ATPase subunit H
K03662 ATPeVS1; V-type H+-transporting ATPase S1 subunit
K02155 ATPeV0C; V-type H+-transporting ATPase 16kDa proteolipid subunit
K03661 ATPeV0B; V-type H+-transporting ATPase 21kDa proteolipid subunit
K13289 CTSA; cathepsin A (carboxypeptidase C) [EC:3.4.16.5]
K01363 CTSB; cathepsin B [EC:3.4.22.1]
K01275 CTSC; cathepsin C [EC:3.4.14.1]
K01379 CTSD; cathepsin D [EC:3.4.23.5]
K01382 CTSE; cathepsin E [EC:3.4.23.34]
K01373 CTSF; cathepsin F [EC:3.4.22.41]
K01319 CTSG; cathepsin G [EC:3.4.21.20]
K01366 CTSH; cathepsin H [EC:3.4.22.16]
K01371 CTSK; cathepsin K [EC:3.4.22.38]
K01365 CTSL; cathepsin L [EC:3.4.22.15]
K01374 CTSO; cathepsin O [EC:3.4.22.42]
K01368 CTSS; cathepsin S [EC:3.4.22.27]
K01375 CTSL2; cathepsin V [EC:3.4.22.43]
K08569 CTSW; cathepsin W [EC:3.4.22.-]
K08568 CTSZ; cathepsin X [EC:3.4.18.1]
K08565 NAPSA; napsin-A [EC:3.4.23.-]
K01369 LGMN; legumain [EC:3.4.22.34]
K01279 TPP1; tripeptidyl-peptidase I [EC:3.4.14.9]
K01189 GLA; alpha-galactosidase [EC:3.2.1.22]
K12309 GLB1; beta-galactosidase [EC:3.2.1.23]
K12316 GAA; lysosomal alpha-glucosidase [EC:3.2.1.20]
K01201 GBA; glucosylceramidase [EC:3.2.1.45]
K01217 IDUA; L-iduronidase [EC:3.2.1.76]
K01204 NAGA; alpha-N-acetylgalactosaminidase [EC:3.2.1.49]
K01205 NAGLU; alpha-N-acetylglucosaminidase [EC:3.2.1.50]
K01202 GALC; galactosylceramidase [EC:3.2.1.46]
K01195 uidA; beta-glucuronidase [EC:3.2.1.31]
K01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]
K01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]
K12373 HEXA_B; hexosaminidase [EC:3.2.1.52]
K12373 HEXA_B; hexosaminidase [EC:3.2.1.52]
K01192 E3.2.1.25; beta-mannosidase [EC:3.2.1.25]
K12311 MAN2B1; lysosomal alpha-mannosidase [EC:3.2.1.24]
K01186 NEU1; sialidase-1 [EC:3.2.1.18]
K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35]
K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35]
K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35]
K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35]
K01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35]
K01134 ARSA; arylsulfatase A [EC:3.1.6.8]
K01135 ARSB; arylsulfatase B [EC:3.1.6.12]
K12381 ARSG; arylsulfatase G [EC:3.1.6.-]
K01132 GALNS; N-acetylgalactosamine-6-sulfatase [EC:3.1.6.4]
K01137 GNS; N-acetylglucosamine-6-sulfatase [EC:3.1.6.14]
K01136 IDS; iduronate 2-sulfatase [EC:3.1.6.13]
K01565 SGSH; N-sulfoglucosamine sulfohydrolase [EC:3.10.1.1]
K01052 LIPA; lysosomal acid lipase/cholesteryl ester hydrolase [EC:3.1.1.13]
K06129 LYPLA3; lysophospholipase III [EC:3.1.1.5]
K01158 DNASE2; deoxyribonuclease II [EC:3.1.22.1]
K01158 DNASE2; deoxyribonuclease II [EC:3.1.22.1]
K14410 ACP2; lysosomal acid phosphatase [EC:3.1.3.2]
K14379 ACP5; tartrate-resistant acid phosphatase type 5 [EC:3.1.3.2]
K12350 SMPD1; sphingomyelin phosphodiesterase [EC:3.1.4.12]
K12348 ASAH1; acid ceramidase [EC:3.5.1.23]
K01444 AGA; N4-(beta-N-acetylglucosaminyl)-L-asparaginase [EC:3.5.1.26]
K12382 PSAP; saposin
K12382 PSAP; saposin
K12383 GM2A; ganglioside GM2 activator
K01074 PPT; palmitoyl-protein thioesterase [EC:3.1.2.22]
K01074 PPT; palmitoyl-protein thioesterase [EC:3.1.2.22]
K06528 LAMP1_2; lysosomal-associated membrane protein 1/2
K06528 LAMP1_2; lysosomal-associated membrane protein 1/2
K06562 LAMP3; lysosomal-associated membrane protein 3
K06501 CD68; CD68 antigen
K06497 CD63; CD63 antigen
K12384 SCARB2; lysosome membrane protein 2
K12385 NPC1; Niemann-Pick C1 protein
K13443 NPC2; Niemann-Pick C2 protein
K12386 CTNS; cystinosin
K12301 SLC17A5; MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 5
K12347 SLC11A1; natural resistance-associated macrophage protein 1
K21398 SLC11A2; natural resistance-associated macrophage protein 2
K12387 LAPTM; lysosomal-associated transmembrane protein
K12387 LAPTM; lysosomal-associated transmembrane protein
K12387 LAPTM; lysosomal-associated transmembrane protein
K05642 ABCA2; ATP-binding cassette, subfamily A (ABC1), member 2
K05656 ABCB9; ATP-binding cassette, subfamily B (MDR/TAP), member 9
K06546 CD164; CD164 antigen
K12305 ENTPD4; ectonucleoside triphosphate diphosphohydrolase 4 [EC:3.6.1.6]
K12388 SORT1; sortilin
K12389 BTS; battenin
K12390 CLN5; ceroid-lipofuscinosis neuronal protein 5
K12307 MSFD8; MFS transporter, ceroid-lipofuscinosis neuronal protein 7
K10532 HGSNAT; heparan-alpha-glucosaminide N-acetyltransferase [EC:2.3.1.78]
K13444 SUMF1; formylglycine-generating enzyme [EC:1.8.3.7]
K08239 GNPTAB; UDP-N-acetylglucosamine-lysosomal-enzyme [EC:2.7.8.17]
K10087 GNPTG; N-acetylglucosamine-1-phosphate transferase, gamma subunit
K01125 NAGPA; N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase [EC:3.1.4.45]
K06564 IGF2R; insulin-like growth factor 2 receptor
K10089 M6PR; cation-dependent mannose-6-phosphate receptor
K04644 CLTA; clathrin light chain A
K04645 CLTB; clathrin light chain B
K04646 CLTC; clathrin heavy chain
K04646 CLTC; clathrin heavy chain
K12391 AP1G1; AP-1 complex subunit gamma-1
K12391 AP1G1; AP-1 complex subunit gamma-1
K12392 AP1B1; AP-1 complex subunit beta-1
K12393 AP1M; AP-1 complex subunit mu
K12393 AP1M; AP-1 complex subunit mu
K12394 AP1S1_2; AP-1 complex subunit sigma 1/2
K12394 AP1S1_2; AP-1 complex subunit sigma 1/2
K12395 AP1S3; AP-1 complex subunit sigma-3
K12396 AP3D; AP-3 complex subunit delta
K12397 AP3B; AP-3 complex subunit beta
K12397 AP3B; AP-3 complex subunit beta
K12398 AP3M; AP-3 complex subunit mu
K12398 AP3M; AP-3 complex subunit mu
K12399 AP3S; AP-3 complex subunit sigma
K12399 AP3S; AP-3 complex subunit sigma
K12400 AP4E1; AP-4 complex subunit epsilon-1
K12401 AP4B1; AP-4 complex subunit beta-1
K12402 AP4M1; AP-4 complex subunit mu-1
K12403 AP4S1; AP-4 complex subunit sigma-1
K12404 GGA; ADP-ribosylation factor-binding protein GGA
K12404 GGA; ADP-ribosylation factor-binding protein GGA
K12404 GGA; ADP-ribosylation factor-binding protein GGA
K04992 MCOLN1; mucolipin 1
K19363 LITAF; lipopolysaccharide-induced tumor necrosis factor-alpha factor
     04146 Peroxisome [PATH:hsa04146]
     04140 Autophagy - animal [PATH:hsa04140]
     04138 Autophagy - yeast
     04136 Autophagy - other [PATH:hsa04136]
     04137 Mitophagy - animal [PATH:hsa04137]
     04139 Mitophagy - yeast
 
   09143 Cell growth and death
     04110 Cell cycle [PATH:hsa04110]
     04111 Cell cycle - yeast
     04112 Cell cycle - Caulobacter
     04113 Meiosis - yeast
     04114 Oocyte meiosis [PATH:hsa04114]
     04210 Apoptosis [PATH:hsa04210]
     04214 Apoptosis - fly
     04215 Apoptosis - multiple species [PATH:hsa04215]
     04216 Ferroptosis [PATH:hsa04216]
     04217 Necroptosis [PATH:hsa04217]
       7124 TNF; tumor necrosis factor
       7132 TNFRSF1A; TNF receptor superfamily member 1A
       8717 TRADD; TNFRSF1A associated via death domain
       7186 TRAF2; TNF receptor associated factor 2
       7188 TRAF5; TNF receptor associated factor 5
       8737 RIPK1; receptor interacting serine/threonine kinase 1
       329 BIRC2; baculoviral IAP repeat containing 2
       330 BIRC3; baculoviral IAP repeat containing 3
       331 XIAP; X-linked inhibitor of apoptosis
       10616 RBCK1; RANBP2-type and C3HC4-type zinc finger containing 1
       55072 RNF31; ring finger protein 31
       81858 SHARPIN; SHANK associated RH domain interactor
       124044 SPATA2L; spermatogenesis associated 2 like
       9825 SPATA2; spermatogenesis associated 2
       1540 CYLD; CYLD lysine 63 deubiquitinase
       8772 FADD; Fas associated via death domain
       841 CASP8; caspase 8
       8837 CFLAR; CASP8 and FADD like apoptosis regulator
       11035 RIPK3; receptor interacting serine/threonine kinase 3
       1536 CYBB; cytochrome b-245 beta chain
       815 CAMK2A; calcium/calmodulin dependent protein kinase II alpha
       817 CAMK2D; calcium/calmodulin dependent protein kinase II delta
       816 CAMK2B; calcium/calmodulin dependent protein kinase II beta
       818 CAMK2G; calcium/calmodulin dependent protein kinase II gamma
       291 SLC25A4; solute carrier family 25 member 4
       292 SLC25A5; solute carrier family 25 member 5
       293 SLC25A6; solute carrier family 25 member 6
       83447 SLC25A31; solute carrier family 25 member 31
       5481 PPID; peptidylprolyl isomerase D
       7416 VDAC1; voltage dependent anion channel 1
       7417 VDAC2; voltage dependent anion channel 2
       7419 VDAC3; voltage dependent anion channel 3
       2747 GLUD2; glutamate dehydrogenase 2
       2746 GLUD1; glutamate dehydrogenase 1
       2752 GLUL; glutamate-ammonia ligase
       5836 PYGL; glycogen phosphorylase L
       5837 PYGM; glycogen phosphorylase, muscle associated
       5834 PYGB; glycogen phosphorylase B
       5599 MAPK8; mitogen-activated protein kinase 8
       5602 MAPK10; mitogen-activated protein kinase 10
       5601 MAPK9; mitogen-activated protein kinase 9
       2495 FTH1; ferritin heavy chain 1
       2512 FTL; ferritin light chain
       123745 PLA2G4E; phospholipase A2 group IVE
       5321 PLA2G4A; phospholipase A2 group IVA
       8681 JMJD7-PLA2G4B; JMJD7-PLA2G4B readthrough
       100137049 PLA2G4B; phospholipase A2 group IVB
       8605 PLA2G4C; phospholipase A2 group IVC
       283748 PLA2G4D; phospholipase A2 group IVD
       255189 PLA2G4F; phospholipase A2 group IVF
       246 ALOX15; arachidonate 15-lipoxygenase
       823 CAPN1; calpain 1
       824 CAPN2; calpain 2
       6609 SMPD1; sphingomyelin phosphodiesterase 1
       197259 MLKL; mixed lineage kinase domain like pseudokinase
       192111 PGAM5; PGAM family member 5, mitochondrial serine/threonine protein phosphatase
       10059 DNM1L; dynamin 1 like
       114548 NLRP3; NLR family pyrin domain containing 3
       29108 PYCARD; PYD and CARD domain containing
       834 CASP1; caspase 1
       3553 IL1B; interleukin 1 beta
       27243 CHMP2A; charged multivesicular body protein 2A
       25978 CHMP2B; charged multivesicular body protein 2B
       51652 CHMP3; charged multivesicular body protein 3
       100526767 RNF103-CHMP3; RNF103-CHMP3 readthrough
       92421 CHMP4C; charged multivesicular body protein 4C
       128866 CHMP4B; charged multivesicular body protein 4B
       29082 CHMP4A; charged multivesicular body protein 4A
       79643 CHMP6; charged multivesicular body protein 6
       9525 VPS4B; vacuolar protein sorting 4 homolog B
       27183 VPS4A; vacuolar protein sorting 4 homolog A
       57132 CHMP1B; charged multivesicular body protein 1B
       5119 CHMP1A; charged multivesicular body protein 1A
       51510 CHMP5; charged multivesicular body protein 5
       91782 CHMP7; charged multivesicular body protein 7
       54822 TRPM7; transient receptor potential cation channel subfamily M member 7
       3552 IL1A; interleukin 1 alpha
       90865 IL33; interleukin 33
       3146 HMGB1; high mobility group box 1
       8743 TNFSF10; TNF superfamily member 10
       8797 TNFRSF10A; TNF receptor superfamily member 10a
       8795 TNFRSF10B; TNF receptor superfamily member 10b
       356 FASLG; Fas ligand
       355 FAS; Fas cell surface death receptor
       11124 FAF1; Fas associated factor 1
       3439 IFNA1; interferon alpha 1
       3440 IFNA2; interferon alpha 2
       3441 IFNA4; interferon alpha 4
       3442 IFNA5; interferon alpha 5
       3443 IFNA6; interferon alpha 6
       3444 IFNA7; interferon alpha 7
       3445 IFNA8; interferon alpha 8
       3446 IFNA10; interferon alpha 10
       3447 IFNA13; interferon alpha 13
       3448 IFNA14; interferon alpha 14
       3449 IFNA16; interferon alpha 16
       3451 IFNA17; interferon alpha 17
       3452 IFNA21; interferon alpha 21
       3456 IFNB1; interferon beta 1
       3458 IFNG; interferon gamma
       3454 IFNAR1; interferon alpha and beta receptor subunit 1
       3455 IFNAR2; interferon alpha and beta receptor subunit 2
       3459 IFNGR1; interferon gamma receptor 1
       3460 IFNGR2; interferon gamma receptor 2
       3716 JAK1; Janus kinase 1
       3717 JAK2; Janus kinase 2
       3718 JAK3; Janus kinase 3
       7297 TYK2; tyrosine kinase 2
       6772 STAT1; signal transducer and activator of transcription 1
       6773 STAT2; signal transducer and activator of transcription 2
       6774 STAT3; signal transducer and activator of transcription 3
       6775 STAT4; signal transducer and activator of transcription 4
       6776 STAT5A; signal transducer and activator of transcription 5A
       6777 STAT5B; signal transducer and activator of transcription 5B
       6778 STAT6; signal transducer and activator of transcription 6
       10379 IRF9; interferon regulatory factor 9
       5610 EIF2AK2; eukaryotic translation initiation factor 2 alpha kinase 2
       7099 TLR4; toll like receptor 4
       353376 TICAM2; toll like receptor adaptor molecule 2
       148022 TICAM1; toll like receptor adaptor molecule 1
       7098 TLR3; toll like receptor 3
       81030 ZBP1; Z-DNA binding protein 1
       27005 USP21; ubiquitin specific peptidase 21
       8878 SQSTM1; sequestosome 1
       3320 HSP90AA1; heat shock protein 90 alpha family class A member 1
       3326 HSP90AB1; heat shock protein 90 alpha family class B member 1
       7128 TNFAIP3; TNF alpha induced protein 3
       142 PARP1; poly(ADP-ribose) polymerase 1
       637 BID; BH3 interacting domain death agonist
       581 BAX; BCL2 associated X, apoptosis regulator
       9131 AIFM1; apoptosis inducing factor mitochondria associated 1
       3014 H2AX; H2A.X variant histone
       8338 H2AC20; H2A clustered histone 20
       85235 H2AC12; H2A clustered histone 12
       221613 H2AC1; H2A clustered histone 1
       92815 H2AW; H2A.W histone
       83740 H2AB3; H2A.B variant histone 3
       3012 H2AC8; H2A clustered histone 8
       8335 H2AC4; H2A clustered histone 4
       55506 MACROH2A2; macroH2A.2 histone
       9555 MACROH2A1; macroH2A.1 histone
       723790 H2AC19; H2A clustered histone 19
       55766 H2AJ; H2A.J histone
       474382 H2AB1; H2A.B variant histone 1
       8336 H2AC17; H2A clustered histone 17
       8337 H2AC18; H2A clustered histone 18
       8969 H2AC11; H2A clustered histone 11
       317772 H2AC21; H2A clustered histone 21
       94239 H2AZ2; H2A.Z variant histone 2
       3013 H2AC7; H2A clustered histone 7
       3015 H2AZ1; H2A.Z variant histone 1
       8330 H2AC15; H2A clustered histone 15
       8334 H2AC6; H2A clustered histone 6
       8329 H2AC13; H2A clustered histone 13
       8331 H2AC14; H2A clustered histone 14
       8332 H2AC16; H2A clustered histone 16
       474381 H2AB2; H2A.B variant histone 2
       5478 PPIA; peptidylprolyl isomerase A
       596 BCL2; BCL2 apoptosis regulator
K03156 TNF; tumor necrosis factor superfamily, member 2
K03158 TNFRSF1A; tumor necrosis factor receptor superfamily member 1A
K03171 TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K09849 TRAF5; TNF receptor-associated factor 5
K02861 RIPK1; receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1]
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
K04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]
K10630 RBCK1; RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.31]
K11974 RNF31; E3 ubiquitin-protein ligase RNF31 [EC:2.3.2.31]
K20894 SHARPIN; shank-associated RH domain-interacting protein
K17595 SPATA2; spermatogenesis-associated protein 2
K17595 SPATA2; spermatogenesis-associated protein 2
K08601 CYLD; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]
K02373 FADD; FAS-associated death domain protein
K04398 CASP8; caspase 8 [EC:3.4.22.61]
K04724 CFLAR; CASP8 and FADD-like apoptosis regulator
K08847 RIPK3; receptor-interacting serine/threonine-protein kinase 3 [EC:2.7.11.1]
K21421 NOX2; NADPH oxidase 2 [EC:1.-.-.-]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31
K05864 PPID; peptidyl-prolyl isomerase D [EC:5.2.1.8]
K05862 VDAC1; voltage-dependent anion channel protein 1
K15040 VDAC2; voltage-dependent anion channel protein 2
K15041 VDAC3; voltage-dependent anion channel protein 3
K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
K01915 glnA; glutamine synthetase [EC:6.3.1.2]
K00688 PYG; glycogen phosphorylase [EC:2.4.1.1]
K00688 PYG; glycogen phosphorylase [EC:2.4.1.1]
K00688 PYG; glycogen phosphorylase [EC:2.4.1.1]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K00522 FTH1; ferritin heavy chain [EC:1.16.3.2]
K13625 FTL; ferritin light chain
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K16342 PLA2G4; cytosolic phospholipase A2 [EC:3.1.1.4]
K00460 ALOX15; arachidonate 15-lipoxygenase [EC:1.13.11.33]
K01367 CAPN1; calpain-1 [EC:3.4.22.52]
K03853 CAPN2; calpain-2 [EC:3.4.22.53]
K12350 SMPD1; sphingomyelin phosphodiesterase [EC:3.1.4.12]
K08849 MLKL; mixed lineage kinase domain-like [EC:2.7.11.1]
K15637 PGAM5; serine/threonine-protein phosphatase PGAM5 [EC:3.1.3.16]
K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
K12800 NLRP3; NACHT, LRR and PYD domains-containing protein 3
K12799 PYCARD; apoptosis-associated speck-like protein containing a CARD
K01370 CASP1; caspase 1 [EC:3.4.22.36]
K04519 IL1B; interleukin 1 beta
K12191 CHMP2A; charged multivesicular body protein 2A
K12192 CHMP2B; charged multivesicular body protein 2B
K12193 VPS24; charged multivesicular body protein 3
K12193 VPS24; charged multivesicular body protein 3
K12194 CHMP4; charged multivesicular body protein 4
K12194 CHMP4; charged multivesicular body protein 4
K12194 CHMP4; charged multivesicular body protein 4
K12195 CHMP6; charged multivesicular body protein 6
K12196 VPS4; vacuolar protein-sorting-associated protein 4
K12196 VPS4; vacuolar protein-sorting-associated protein 4
K12197 CHMP1; charged multivesicular body protein 1
K12197 CHMP1; charged multivesicular body protein 1
K12198 CHMP5; charged multivesicular body protein 5
K15053 CHMP7; charged multivesicular body protein 7
K04982 TRPM7; transient receptor potential cation channel subfamily M member 7 [EC:2.7.11.1]
K04383 IL1A; interleukin 1 alpha
K12967 IL33; interleukin 33
K10802 HMGB1; high mobility group protein B1
K04721 TNFSF10; tumor necrosis factor ligand superfamily member 10
K04722 TNFRSF10A_B; tumor necrosis factor receptor superfamily member 10A/B
K04722 TNFRSF10A_B; tumor necrosis factor receptor superfamily member 10A/B
K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6
K04390 TNFRSF6; tumor necrosis factor receptor superfamily member 6
K20703 FAF1; FAS-associated factor 1
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05414 IFNA; interferon alpha
K05415 IFNB; interferon beta
K04687 IFNG; interferon gamma
K05130 IFNAR1; interferon receptor 1
K05131 IFNAR2; interferon receptor 2
K05132 IFNGR1; interferon gamma receptor 1
K05133 IFNGR2; interferon gamma receptor 2
K11217 JAK1; Janus kinase 1 [EC:2.7.10.2]
K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
K11218 JAK3; Janus kinase 3 [EC:2.7.10.2]
K11219 TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]
K11220 STAT1; signal transducer and activator of transcription 1
K11221 STAT2; signal transducer and activator of transcription 2
K04692 STAT3; signal transducer and activator of transcription 3
K11222 STAT4; signal transducer and activator of transcription 4
K11223 STAT5A; signal transducer and activator of transcription 5A
K11224 STAT5B; signal transducer and activator of transcription 5B
K11225 STAT6; signal transducer and activator of transcription 6
K04693 IRF9; interferon regulatory factor 9
K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
K10160 TLR4; toll-like receptor 4
K05409 TIRP; TRIF-related adaptor molecule
K05842 TRIF; toll-like receptor adapter molecule 1
K05401 TLR3; toll-like receptor 3
K12965 ZBP1; Z-DNA binding protein 1
K21634 USP21; ubiquitin carboxyl-terminal hydrolase 21 [EC:3.4.19.12]
K14381 SQSTM1; sequestosome 1
K04079 HSP90A; molecular chaperone HtpG
K04079 HSP90A; molecular chaperone HtpG
K11859 TNFAIP3; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12]
K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
K04726 BID; BH3 interacting domain death agonist
K02159 BAX; apoptosis regulator BAX
K04727 AIFM1; apoptosis-inducing factor 1 [EC:1.-.-.-]
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K11251 H2A; histone H2A
K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]
K02161 BCL2; apoptosis regulator Bcl-2
     04115 p53 signaling pathway [PATH:hsa04115]
     04218 Cellular senescence [PATH:hsa04218]
 
   09144 Cellular community - eukaryotes
 
   09145 Cellular community - prokaryotes
 
   09142 Cell motility
 
 09150 Organismal Systems
 
 09160 Human Diseases
 
 09180 Brite Hierarchies
 
 09190 Not Included in Pathway or Brite

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: January 17, 2021