KEGG Orthology (KO) - Homo sapiens (human)

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     KO
 09100 Metabolism
 
 09120 Genetic Information Processing
 
   09121 Transcription
 
   09122 Translation
 
   09123 Folding, sorting and degradation
     03060 Protein export [PATH:hsa03060]
     04141 Protein processing in endoplasmic reticulum [PATH:hsa04141]
       29927 SEC61A1; SEC61 translocon subunit alpha 1
       55176 SEC61A2; SEC61 translocon subunit alpha 2
       10952 SEC61B; SEC61 translocon subunit beta
       23480 SEC61G; SEC61 translocon subunit gamma
       7095 SEC62; SEC62 homolog, preprotein translocation factor
       11231 SEC63; SEC63 homolog, protein translocation regulator
       6184 RPN1; ribophorin I
       6185 RPN2; ribophorin II
       1603 DAD1; defender against cell death 1
       7991 TUSC3; tumor suppressor candidate 3
       1650 DDOST; dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit
       3703 STT3A; STT3 oligosaccharyltransferase complex catalytic subunit A
       201595 STT3B; STT3 oligosaccharyltransferase complex catalytic subunit B
       7841 MOGS; mannosyl-oligosaccharide glucosidase
       10970 CKAP4; cytoskeleton associated protein 4
       6238 RRBP1; ribosome binding protein 1
       64374 SIL1; SIL1 nucleotide exchange factor
       10525 HYOU1; hypoxia up-regulated 1
       3309 HSPA5; heat shock protein family A (Hsp70) member 5
       51726 DNAJB11; DnaJ heat shock protein family (Hsp40) member B11
       64215 DNAJC1; DnaJ heat shock protein family (Hsp40) member C1
       5611 DNAJC3; DnaJ heat shock protein family (Hsp40) member C3
       54431 DNAJC10; DnaJ heat shock protein family (Hsp40) member C10
       7184 HSP90B1; heat shock protein 90 beta family member 1
       23193 GANAB; glucosidase II alpha subunit
       5589 PRKCSH; protein kinase C substrate 80K-H
       821 CANX; calnexin
       2923 PDIA3; protein disulfide isomerase family A member 3
       811 CALR; calreticulin
       10905 MAN1A2; mannosidase alpha class 1A member 2
       57134 MAN1C1; mannosidase alpha class 1C member 1
       4121 MAN1A1; mannosidase alpha class 1A member 1
       11253 MAN1B1; mannosidase alpha class 1B member 1
       10960 LMAN2; lectin, mannose binding 2
       3998 LMAN1; lectin, mannose binding 1
       79748 LMAN1L; lectin, mannose binding 1 like
       10113 PREB; prolactin regulatory element binding
       56681 SAR1A; secretion associated Ras related GTPase 1A
       51128 SAR1B; secretion associated Ras related GTPase 1B
       6396 SEC13; SEC13 homolog, nuclear pore and COPII coat complex component
       22872 SEC31A; SEC31 homolog A, COPII coat complex component
       25956 SEC31B; SEC31 homolog B, COPII coat complex component
       10483 SEC23B; SEC23 homolog B, COPII coat complex component
       10484 SEC23A; Sec23 homolog A, COPII coat complex component
       10427 SEC24B; SEC24 homolog B, COPII coat complex component
       10802 SEC24A; SEC24 homolog A, COPII coat complex component
       9632 SEC24C; SEC24 homolog C, COPII coat complex component
       9871 SEC24D; SEC24 homolog D, COPII coat complex component
       55757 UGGT2; UDP-glucose glycoprotein glucosyltransferase 2
       56886 UGGT1; UDP-glucose glycoprotein glucosyltransferase 1
       9695 EDEM1; ER degradation enhancing alpha-mannosidase like protein 1
       55741 EDEM2; ER degradation enhancing alpha-mannosidase like protein 2
       111089941 MMP24-AS1-EDEM2; MMP24-AS1-EDEM2 readthrough
       80267 EDEM3; ER degradation enhancing alpha-mannosidase like protein 3
       5034 P4HB; prolyl 4-hydroxylase subunit beta
       9601 PDIA4; protein disulfide isomerase family A member 4
       10130 PDIA6; protein disulfide isomerase family A member 6
       10961 ERP29; endoplasmic reticulum protein 29
       81567 TXNDC5; thioredoxin domain containing 5
       30001 ERO1A; endoplasmic reticulum oxidoreductase 1 alpha
       56605 ERO1B; endoplasmic reticulum oxidoreductase 1 beta
       10956 OS9; OS9 endoplasmic reticulum lectin
       27248 ERLEC1; endoplasmic reticulum lectin 1
       6745 SSR1; signal sequence receptor subunit 1
       6746 SSR2; signal sequence receptor subunit 2
       6747 SSR3; signal sequence receptor subunit 3
       6748 SSR4; signal sequence receptor subunit 4
       10134 BCAP31; B cell receptor associated protein 31
       23471 TRAM1; translocation associated membrane protein 1
       133022 TRAM1L1; translocation associated membrane protein 1 like 1
       79139 DERL1; derlin 1
       51009 DERL2; derlin 2
       91319 DERL3; derlin 3
       23190 UBXN4; UBX domain protein 4
       51035 UBXN1; UBX domain protein 1
       165324 UBXN2A; UBX domain protein 2A
       80700 UBXN6; UBX domain protein 6
       7993 UBXN8; UBX domain protein 8
       55968 NSFL1C; NSFL1 cofactor
       258010 SVIP; small VCP interacting protein
       7415 VCP; valosin containing protein
       55666 NPLOC4; NPL4 homolog, ubiquitin recognition factor
       7353 UFD1; ubiquitin recognition factor in ER associated degradation 1
       3312 HSPA8; heat shock protein family A (Hsp70) member 8
       3303 HSPA1A; heat shock protein family A (Hsp70) member 1A
       3306 HSPA2; heat shock protein family A (Hsp70) member 2
       3305 HSPA1L; heat shock protein family A (Hsp70) member 1 like
       3304 HSPA1B; heat shock protein family A (Hsp70) member 1B
       3310 HSPA6; heat shock protein family A (Hsp70) member 6
       3301 DNAJA1; DnaJ heat shock protein family (Hsp40) member A1
       10294 DNAJA2; DnaJ heat shock protein family (Hsp40) member A2
       3337 DNAJB1; DnaJ heat shock protein family (Hsp40) member B1
       3300 DNAJB2; DnaJ heat shock protein family (Hsp40) member B2
       54788 DNAJB12; DnaJ heat shock protein family (Hsp40) member B12
       80331 DNAJC5; DnaJ heat shock protein family (Hsp40) member C5
       85479 DNAJC5B; DnaJ heat shock protein family (Hsp40) member C5 beta
       285126 DNAJC5G; DnaJ heat shock protein family (Hsp40) member C5 gamma
       3320 HSP90AA1; heat shock protein 90 alpha family class A member 1
       3326 HSP90AB1; heat shock protein 90 alpha family class B member 1
       10808 HSPH1; heat shock protein family H (Hsp110) member 1
       22824 HSPA4L; heat shock protein family A (Hsp70) member 4 like
       573 BAG1; BAG cochaperone 1
       9532 BAG2; BAG cochaperone 2
       23640 HSPBP1; HSPA (Hsp70) binding protein 1
       1409 CRYAA; crystallin alpha A
       102724652 CRYAA2; crystallin alpha A2
       1410 CRYAB; crystallin alpha B
       55432 YOD1; YOD1 deubiquitinase
       9373 PLAA; phospholipase A2 activating protein
       5887 RAD23B; RAD23 homolog B, nucleotide excision repair protein
       5886 RAD23A; RAD23 homolog A, nucleotide excision repair protein
       29979 UBQLN1; ubiquilin 1
       29978 UBQLN2; ubiquilin 2
       50613 UBQLN3; ubiquilin 3
       56893 UBQLN4; ubiquilin 4
       55768 NGLY1; N-glycanase 1
       4287 ATXN3; ataxin 3
       92552 ATXN3L; ataxin 3 like
       10277 UBE4B; ubiquitination factor E4B
       27102 EIF2AK1; eukaryotic translation initiation factor 2 alpha kinase 1
       5610 EIF2AK2; eukaryotic translation initiation factor 2 alpha kinase 2
       9451 EIF2AK3; eukaryotic translation initiation factor 2 alpha kinase 3
       440275 EIF2AK4; eukaryotic translation initiation factor 2 alpha kinase 4
       1965 EIF2S1; eukaryotic translation initiation factor 2 subunit alpha
       4780 NFE2L2; nuclear factor, erythroid 2 like 2
       468 ATF4; activating transcription factor 4
       23645 PPP1R15A; protein phosphatase 1 regulatory subunit 15A
       1649 DDIT3; DNA damage inducible transcript 3
       596 BCL2; BCL2 apoptosis regulator
       22926 ATF6; activating transcription factor 6
       1388 ATF6B; activating transcription factor 6 beta
       7466 WFS1; wolframin ER transmembrane glycoprotein
       8720 MBTPS1; membrane bound transcription factor peptidase, site 1
       51360 MBTPS2; membrane bound transcription factor peptidase, site 2
       7494 XBP1; X-box binding protein 1
       2081 ERN1; endoplasmic reticulum to nucleus signaling 1
       7186 TRAF2; TNF receptor associated factor 2
       4217 MAP3K5; mitogen-activated protein kinase kinase kinase 5
       5609 MAP2K7; mitogen-activated protein kinase kinase 7
       5599 MAPK8; mitogen-activated protein kinase 8
       5602 MAPK10; mitogen-activated protein kinase 10
       5601 MAPK9; mitogen-activated protein kinase 9
       581 BAX; BCL2 associated X, apoptosis regulator
       578 BAK1; BCL2 antagonist/killer 1
       823 CAPN1; calpain 1
       824 CAPN2; calpain 2
       100506742 CASP12; caspase 12 (gene/pseudogene)
       10299 MARCHF6; membrane associated ring-CH-type finger 6
       51465 UBE2J1; ubiquitin conjugating enzyme E2 J1
       118424 UBE2J2; ubiquitin conjugating enzyme E2 J2
       7326 UBE2G1; ubiquitin conjugating enzyme E2 G1
       7327 UBE2G2; ubiquitin conjugating enzyme E2 G2
       84447 SYVN1; synoviolin 1
       6048 RNF5; ring finger protein 5
       91445 RNF185; ring finger protein 185
       55829 SELENOS; selenoprotein S
       6400 SEL1L; SEL1L adaptor subunit of ERAD E3 ubiquitin ligase
       80343 SEL1L2; SEL1L2 adaptor subunit of ERAD E3 ligase
       9709 HERPUD1; homocysteine inducible ER protein with ubiquitin like domain 1
       267 AMFR; autocrine motility factor receptor
       10273 STUB1; STIP1 homology and U-box containing protein 1
       51619 UBE2D4; ubiquitin conjugating enzyme E2 D4 (putative)
       7321 UBE2D1; ubiquitin conjugating enzyme E2 D1
       7322 UBE2D2; ubiquitin conjugating enzyme E2 D2
       7323 UBE2D3; ubiquitin conjugating enzyme E2 D3
       5071 PRKN; parkin RBR E3 ubiquitin protein ligase
       9978 RBX1; ring-box 1
       8454 CUL1; cullin 1
       6500 SKP1; S-phase kinase associated protein 1
       26232 FBXO2; F-box protein 2
       26270 FBXO6; F-box protein 6
K10956 SEC61A; protein transport protein SEC61 subunit alpha
K10956 SEC61A; protein transport protein SEC61 subunit alpha
K09481 SEC61B; protein transport protein SEC61 subunit beta
K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
K12275 SEC62; translocation protein SEC62
K09540 SEC63; translocation protein SEC63
K12666 OST1; oligosaccharyltransferase complex subunit alpha (ribophorin I)
K12667 SWP1; oligosaccharyltransferase complex subunit delta (ribophorin II)
K12668 OST2; oligosaccharyltransferase complex subunit epsilon
K12669 OST3; oligosaccharyltransferase complex subunit gamma
K12670 WBP1; oligosaccharyltransferase complex subunit beta
K07151 STT3; dolichyl-diphosphooligosaccharide---protein glycosyltransferase [EC:2.4.99.18]
K07151 STT3; dolichyl-diphosphooligosaccharide---protein glycosyltransferase [EC:2.4.99.18]
K01228 MOGS; mannosyl-oligosaccharide glucosidase [EC:3.2.1.106]
K13999 CKAP4; cytoskeleton-associated protein 4
K14000 RRBP1; ribosome-binding protein 1
K14001 SIL1; nucleotide exchange factor SIL1
K09486 HYOU1; hypoxia up-regulated 1
K09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
K09517 DNAJB11; DnaJ homolog subfamily B member 11
K09521 DNAJC1; DnaJ homolog subfamily C member 1
K09523 DNAJC3; DnaJ homolog subfamily C member 3
K09530 DNAJC10; DnaJ homolog subfamily C member 10 [EC:1.8.4.-]
K09487 HSP90B; heat shock protein 90kDa beta
K05546 GANAB; mannosyl-oligosaccharide alpha-1,3-glucosidase [EC:3.2.1.207]
K08288 PRKCSH; protein kinase C substrate 80K-H
K08054 CANX; calnexin
K08056 PDIA3; protein disulfide-isomerase A3 [EC:5.3.4.1]
K08057 CALR; calreticulin
K01230 MAN1A_C; mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]
K01230 MAN1A_C; mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]
K01230 MAN1A_C; mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]
K23741 MAN1B; endoplasmic reticulum Man9GlcNAc2 1,2-alpha-mannosidase [EC:3.2.1.209]
K10082 LMAN2; lectin, mannose-binding 2
K10080 LMAN1; lectin, mannose-binding 1
K10081 LMAN1L; lectin, mannose-binding 1-like
K14003 PREB; prolactin regulatory element-binding protein
K07953 SAR1; GTP-binding protein SAR1 [EC:3.6.5.-]
K07953 SAR1; GTP-binding protein SAR1 [EC:3.6.5.-]
K14004 SEC13; protein transport protein SEC13
K14005 SEC31; protein transport protein SEC31
K14005 SEC31; protein transport protein SEC31
K14006 SEC23; protein transport protein SEC23
K14006 SEC23; protein transport protein SEC23
K14007 SEC24; protein transport protein SEC24
K14007 SEC24; protein transport protein SEC24
K14007 SEC24; protein transport protein SEC24
K14007 SEC24; protein transport protein SEC24
K11718 HUGT; UDP-glucose:glycoprotein glucosyltransferase [EC:2.4.1.-]
K11718 HUGT; UDP-glucose:glycoprotein glucosyltransferase [EC:2.4.1.-]
K10084 EDEM1; ER degradation enhancer, mannosidase alpha-like 1
K10085 EDEM2; ER degradation enhancer, mannosidase alpha-like 2
K10085 EDEM2; ER degradation enhancer, mannosidase alpha-like 2
K10086 EDEM3; ER degradation enhancer, mannosidase alpha-like 3
K09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]
K09582 PDIA4; protein disulfide-isomerase A4 [EC:5.3.4.1]
K09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]
K09586 ERP29; endoplasmic reticulum protein 29
K13984 TXNDC5; thioredoxin domain-containing protein 5
K10950 ERO1L; ERO1-like protein alpha [EC:1.8.4.-]
K10976 ERO1LB; ERO1-like protein beta [EC:1.8.4.-]
K10088 OS9; protein OS-9
K14008 ERLEC1; endoplasmic reticulum lectin 1
K13249 SSR1; translocon-associated protein subunit alpha
K13250 SSR2; translocon-associated protein subunit beta
K13251 SSR3; translocon-associated protein subunit gamma
K04571 SSR4; translocon-associated protein subunit delta
K14009 BCAP31; B-cell receptor-associated protein 31
K14010 TRAM1; translocating chain-associated membrane protein 1
K14010 TRAM1; translocating chain-associated membrane protein 1
K11519 DERL1; Derlin-1
K13989 DERL2_3; Derlin-2/3
K13989 DERL2_3; Derlin-2/3
K24348 UBXN1_4; UBX domain-containing protein 1/4
K24348 UBXN1_4; UBX domain-containing protein 1/4
K24349 UBXN2A; UBX domain-containing protein 2A
K14011 UBXN6; UBX domain-containing protein 6
K24351 UBXN8; UBX domain-containing protein 8
K14012 NSFL1C; UBX domain-containing protein 1
K14014 SVIP; small VCP/p97-interacting protein
K13525 VCP; transitional endoplasmic reticulum ATPase
K14015 NPLOC4; nuclear protein localization protein 4 homolog
K14016 UFD1; ubiquitin fusion degradation protein 1
K03283 HSPA1s; heat shock 70kDa protein 1/2/6/8
K03283 HSPA1s; heat shock 70kDa protein 1/2/6/8
K03283 HSPA1s; heat shock 70kDa protein 1/2/6/8
K03283 HSPA1s; heat shock 70kDa protein 1/2/6/8
K03283 HSPA1s; heat shock 70kDa protein 1/2/6/8
K03283 HSPA1s; heat shock 70kDa protein 1/2/6/8
K09502 DNAJA1; DnaJ homolog subfamily A member 1
K09503 DNAJA2; DnaJ homolog subfamily A member 2
K09507 DNAJB1; DnaJ homolog subfamily B member 1
K09508 DNAJB2; DnaJ homolog subfamily B member 2
K09518 DNAJB12; DnaJ homolog subfamily B member 12
K09525 DNAJC5; DnaJ homolog subfamily C member 5
K09525 DNAJC5; DnaJ homolog subfamily C member 5
K09525 DNAJC5; DnaJ homolog subfamily C member 5
K04079 HSP90A; molecular chaperone HtpG
K04079 HSP90A; molecular chaperone HtpG
K09485 HSP110; heat shock protein 110kDa
K09485 HSP110; heat shock protein 110kDa
K09555 BAG1; BCL2-associated athanogene 1
K09556 BAG2; BCL2-associated athanogene 2
K09562 HSPBP1; hsp70-interacting protein
K09541 CRYAA; crystallin, alpha A
K09541 CRYAA; crystallin, alpha A
K09542 CRYAB; crystallin, alpha B
K13719 OTU1; ubiquitin thioesterase OTU1 [EC:3.1.2.-]
K14018 PLAA; phospholipase A-2-activating protein
K10839 RAD23; UV excision repair protein RAD23
K10839 RAD23; UV excision repair protein RAD23
K04523 UBQLN; ubiquilin
K04523 UBQLN; ubiquilin
K04523 UBQLN; ubiquilin
K04523 UBQLN; ubiquilin
K01456 E3.5.1.52; peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase [EC:3.5.1.52]
K11863 ATXN3; Ataxin-3 [EC:3.4.22.-]
K11863 ATXN3; Ataxin-3 [EC:3.4.22.-]
K10597 UBE4B; ubiquitin conjugation factor E4 B [EC:2.3.2.27]
K16194 EIF2AK1; eukaryotic translation initiation factor 2-alpha kinase 1 [EC:2.7.11.1]
K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
K08860 EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
K16196 EIF2AK4; eukaryotic translation initiation factor 2-alpha kinase 4 [EC:2.7.11.1]
K03237 EIF2S1; translation initiation factor 2 subunit 1
K05638 NFE2L2; nuclear factor erythroid 2-related factor 2
K04374 ATF4; cyclic AMP-dependent transcription factor ATF-4
K14019 PPP1R15A; protein phosphatase 1 regulatory subunit 15A
K04452 DDIT3; DNA damage-inducible transcript 3
K02161 BCL2; apoptosis regulator Bcl-2
K09054 ATF6A; cyclic AMP-dependent transcription factor ATF-6 alpha
K09049 ATF6B; cyclic AMP-dependent transcription factor ATF-6 beta
K14020 WFS1; wolfamin
K08653 MBTPS1; membrane-bound transcription factor site-1 protease [EC:3.4.21.112]
K07765 MBTPS2; S2P endopeptidase [EC:3.4.24.85]
K09027 XBP1; X box-binding protein 1
K08852 ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
K04426 MAP3K5; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
K04431 MAP2K7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
K02159 BAX; apoptosis regulator BAX
K14021 BAK; Bcl-2 homologous antagonist/killer
K01367 CAPN1; calpain-1 [EC:3.4.22.52]
K03853 CAPN2; calpain-2 [EC:3.4.22.53]
K04741 CASP12; caspase 12 [EC:3.4.22.-]
K10661 MARCH6; E3 ubiquitin-protein ligase MARCH6 [EC:2.3.2.27]
K10578 UBE2J1; ubiquitin-conjugating enzyme E2 J1 [EC:2.3.2.23]
K04554 UBE2J2; ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23]
K10575 UBE2G1; ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]
K04555 UBE2G2; ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]
K10601 SYVN1; E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27]
K10666 RNF5; E3 ubiquitin-protein ligase RNF5 [EC:2.3.2.27]
K10666 RNF5; E3 ubiquitin-protein ligase RNF5 [EC:2.3.2.27]
K14025 SELS; selenoprotein S
K14026 SEL1; SEL1 protein
K14026 SEL1; SEL1 protein
K14027 HERPUD1; homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein
K10636 AMFR; autocrine motility factor receptor [EC:2.3.2.27]
K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
K04556 PARK2; parkin [EC:2.3.2.31]
K03868 RBX1; RING-box protein 1 [EC:2.3.2.32]
K03347 CUL1; cullin 1
K03094 SKP1; S-phase kinase-associated protein 1
K10099 FBXO2; F-box protein 2
K10100 FBXO6; F-box protein 6
     04130 SNARE interactions in vesicular transport [PATH:hsa04130]
     04120 Ubiquitin mediated proteolysis [PATH:hsa04120]
     04122 Sulfur relay system [PATH:hsa04122]
     03050 Proteasome [PATH:hsa03050]
     03018 RNA degradation [PATH:hsa03018]
 
   09124 Replication and repair
 
 09130 Environmental Information Processing
 
 09140 Cellular Processes
 
 09150 Organismal Systems
 
 09160 Human Diseases
 
 09180 Brite Hierarchies
 
 09190 Not Included in Pathway or Brite

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: November 27, 2020